US08829103B2
A composite material includes: carbon fibers having an average fiber length of more than about 10 mm and about 100 mm or less; and a thermoplastic resin. The carbon fibers are substantially two-dimensionally-randomly oriented. The composite material includes a carbon fiber bundle (A) in a ratio of more than 0 volume % and less than about 30 volume % to a total volume of the carbon fibers, the carbon fiber bundle (A) including the carbon fibers of a critical single fiber number defined by formula (1) or more. An average number (N) of the carbon fibers in the carbon fiber bundle (A) satisfies formula (2). Critical single fiber number=600/D (1) 1.0×104/D2
US08829101B2
A windmill blade which comprises reinforcing fibers in a toughened resin matrix. The resin matrix is made from a composition which comprises (a) one or more epoxy resins and/or one or more epoxy vinyl ester resins, (b) one or more reactive diluents, and (c) at least one amphiphilic block copolymer. The amphiphilic block copolymer comprises at least two different polyether blocks and is present in the composition in an amount of from about 0.5% to about 10% by volume, based on the total volume of the matrix composition.
US08829098B2
The present invention provides a polylactic acid resin composition, containing a polylactic acid resin and a metal hydrate surface-treated with at least one silane coupling agent selected from an amino-silane coupling agent, a mercapto-silane coupling agent and an isocyanate-silane coupling agent, wherein the content of an alkali metal component in the metal hydrate is not more than 0.2% by mass and a polylactic acid resin molded article produced by molding the polylactic acid resin composition.
US08829097B2
PLA-containing materials, and building components containing such materials, include: polylactic acid (PLA); one or more inorganic pigments; and one or more stabilizers that includes one or more carbodiimide groups.
US08829089B1
A xerographic fuser member that contains a composition comprising a mixture of a polyimide and a neutralized amine alcohol phosphate.
US08829088B1
A xerographic fuser member that contains a composition of a polyimide and an alcohol phosphate.
US08829086B2
Disclosed is a glass fiber-reinforced polycarbonate flame-retardant resin composition which comprises (A) 50 to 75% by weight of polycarbonate having a melt index of 22 g/10 min or more (300° C., 1.2 kg), (B) 3 to 15% by weight of a rubber-modified styrene-based graft copolymer, (C) 3 to 10% by weight of a bulk copolymer of an aromatic vinyl compound and a vinyl cyan compound, (D) 1 to 10% by weight of an ethylene acrylate-based copolymer, (E) 10 to 25% by weight of glass fiber, and (F) 5 to 20% by weight of an aromatic phosphate ester-based compound, and thus advantageously exhibits superior flowability, flame retardancy, hardness, impact resistance and appearance qualities.
US08829082B2
A self-healing capsule may contain a self-healing agent, a polymer shell encapsulating the self-healing agent, and at least one functional group orthogonal to the surface of the polymer shell. This self-healing capsule may be covalently bonded into a polymeric material by the orthogonal functional group. The self-healing capsules may be formed through microencapsulation.
US08829080B2
Disclosed is a coating agent characterized by comprising: a core-shell-type resin particles (A) each having a shell layer and a core layer; a compound (B) having at least one selected from the group consisting of a hydrolysable silyl group and a silanol group and also having an epoxy group; and an aqueous medium, wherein the shell layer comprises (a1) a urethane resin with 2000 to 5500 mmol/kg of an aliphatic cyclic structure and at least one selected from the group consisting of a carboxyl group and a carboxylate group and the core layer comprises (a2) a vinyl polymer having a basic nitrogen-atom-containing group. Further disclosed are a coating agent for a plastic base material and a coating agent for a metallic base material.
US08829072B2
The invention provides a polymer based material comprising a water binding agent present in an amount sufficient to chemically and/or physically absorb and/or adsorb water to prevent degradation of the polymer. The invention also provides a polymer based material comprising a plasticizer or organic solvent as well as a multi-component material or composite including materials encompassing a second polymer and/or an active agent. The invention further provides a pharmaceutical composition comprising the aforesaid polymer based material, which can be used for treatment of bone, cartilage and/or periodontal defects.
US08829060B2
A membrane comprising a blend of a sulfonated poly(aryl ether) and a phenol compound along with methods for making and using the same. Many additional embodiments are described including applications for such membranes.
US08829059B2
Disclosed herein are methanol production processes that include a sweep-based membrane separation step using a membrane that is selective to carbon dioxide over hydrogen. Using the processes of the invention, the efficiency of methanol production from syngas is increased by reducing the compression requirements of the process and/or improving the methanol product yield. In certain embodiments, a hydrogen-rich stream is generated; this hydrogen-rich stream can be sent for other uses. An additional benefit is that the processes of the invention may debottleneck existing methanol plants if more syngas or carbon dioxide is available, allowing for feed of imported carbon dioxide into the synthesis loop. This is a way of sequestering carbon dioxide.
US08829053B2
An antimicrobial composition with synergistic biocidal activity is described which comprises at least one antimicrobial polymeric biguanide and at least one antimicrobial vicinal diol, said vicinal diol comprises at least one monoalkyl glycol, monoalkyl glycerol, or monoacyl glycerol, to diminish or eliminate biofilm communities. Such synergistic interaction is effective in wound treatment, particularly for chronic wounds, burns and battlefield-induced wounds, as well as for disinfecting non-biological surfaces. The antimicrobial composition can also be prepared as viscous solutions or as gels. The antimicrobial composition may be added to a substrate and dried, such as to a catheter, or to a foam, or to a fiber wound dressing, or coated as a viscous solution or gel upon such devices, to provide controlled release antimicrobial activity.
US08829052B2
This invention concerns N-(2-arylamino)aryl sulfonamides, which are inhibitors of MEK and are useful in treatment of cancer and other hyperproliferative diseases.
US08829049B2
The use of cubebin, dibenzylbutyrolactolic lignan, its semi-synthetic and synthetic derivatives for the treatment of erectile dysfunction is shown and disclosed.
US08829044B2
The present invention relates to a stabilized vitamin C derivative with a peptide molecule linked to vitamin C or a pharmaceutically acceptable salt thereof, a method of preparing the same, and a composition containing the same.
US08829043B2
The invention relates to (among other things) oligomer-cannabinoid conjugates and related compounds. A conjugate of the invention, when administered by any of a number of administration routes, exhibits advantages over previously administered un-conjugated cannabinoid compounds.
US08829036B2
Disclosed are compounds of the formula I or a stereoisomer, tautomer, or pharmaceutically acceptable salt or solvate thereof, wherein each variable in Formula 1 are as defined in the specification; and pharmaceutical compositions comprising the compounds of formula I. Also disclosed are methods of inhibiting aspartyl protease, and in particular, the methods of treating cardiovascular diseases, cognitive and neurodegenerative diseases, and the methods of inhibiting of Human Immunodeficiency Virus, plasmepins, cathepsin D and protozoal enzymes. Also disclosed are methods of treating cognitive or neurodegenerative diseases using the compounds of formula I in combination with a cholinesterase inhibitor or a muscarinic m1 agonist or m2 antagonist.
US08829029B2
The present invention relates to compounds of the formula (I) wherein R1, R2, X and n are as defined in the specification as dual modulators of the serotonin 5-HT2a and dopamine D3 receptors, their manufacture, pharmaceutical compositions containing them and their use for the treatment of psychotic disorders, as well as other diseases such as depression and anxiety, drug dependence, dementias and memory impairment.
US08829006B2
The present invention relates to new CGRP-antagonists of general formula I wherein U, V, X, Y, R1, R2, R3 and R4 are defined as mentioned in the description, the tautomers thereof, the isomers thereof, the diastereomers thereof, the enantiomers thereof, the hydrates thereof, the mixtures thereof and the salts thereof as well as the hydrates of the salts, particularly the physiologically acceptable salts thereof with inorganic or organic acids or bases, medicaments containing these compounds, the use thereof and processes for the preparation thereof.
US08829001B2
The present invention relates to a novel piperazine derivative represented by Formula I having an activity for regulating dopamine D3 receptor, stereoisomers thereof, pharmaceutically acceptable salts or solvates, and a pharmaceutical composition comprising the compound, a process for preparing the same, and use thereof in the prevention or treatment of a disease associated with central nervous system dysfunction, such as Parkinson's disease, schizophrenia, drug addiction and relapse, as well as kidney protection and immunoregulation, or as a tool for researching D3R function or diseases associated with D3R dysfunction.
US08829000B2
The invention discloses quinoxaline derivatives or salts thereof having PDE9-inhibiting activity and being useful as treating agent of dysuria and the like, which are represented by the formula (I) in the formula, R1 and R2 each independently stands for hydrogen, halogen, alkyl, alkoxy, acyl, amino and the like, R3 stands for alkyl, aryl, saturated carbocyclic group, saturated heterocyclic group, acyl and the like, R4 stands for hydrogen, hydroxy, alkyl or amino, R5 and R8 each independently stands for hydrogen, halogen, alkyl, alkenyl, alkoxy, cyano or nitro, R6 and R7 each independently stands for hydrogen, halogen, alkyl, alkenyl, alkynyl, alkoxy, cyano, amino, carbocyclic group, heterocyclic group, COR9 or SO2R9, R9 stands for hydrogen, hydroxy, alkyl, amino, pyrrolidin-1-yl, piperidin-1-yl, pyperazin-1-yl or the like, X stands for S or O, and A1, A2 and A3 each independently stands for N or C.
US08828987B2
The invention relates pyridine amide derivative of Formula (I) or a pharmaceutically acceptable salt thereof, wherein R1 and R2 are independently hydrogen, linear o branched (C1-C3)alkyl or joined together they form a cyclopropyl ring; R is independently selected from the group consisting of halogens and trifluoromethyl and p is 1, 2 or 3; A is C or N; E is a group of formula (B) or (C), wherein B is C(O)OH, C(O)O(C1-C3)alkyl, and C is selected from the group consisting of formula (I) m is 1,2 or 3, n is 0 or 1, W is —O—, —O(C1-C3 alkyl)-; —(C1-C3 alkyl)O—; —C(O)—; —C(═N—O(C1-C3 alkyl))-; —NH— or —NH(C1-C3alkyl)-; Ar is phenyl, optionally substituted with one or more substituents selected from the group consisting of halogen, trifluoromethyl, trifluoromethoxy, methyl, —NH(C1-C3alkyl)-; —N(C1-C3alkyl)(C1-C3alkyl)-, a from 5 to 7 membered heterocyclic ring containing one nitrogen atom which is covalently bonded to Ar and optionally containing one or two heteroatoms selected from N, O and S; and a 5- or 6-membered heteroaromatic ring containing 1 to 3 heteroatoms selected from S, O e N, such heteroaromatic ring being substituted with one or two substituents selected from the group consisting of (C1-C3)alkyl, (C3-C5)cycloalkyloxy, (C1-C3)alkylcarbonyl. The compounds of the invention could be used for manufacturing a medicament for the treatment of pathologies which require the use of an antagonist of the EP4 receptor, such as the treatment of acute and chronic pain, inflammatory pain, osteoarthritis, inflammation-associated disorder as arthritis, rheumatoid arthritis, cancer, endometriosis and migraine.
US08828985B2
This invention relates to novel compounds of the Formula (I) pharmaceutically acceptable salts thereof, and pharmaceutical compositions thereof, which are useful for the therapeutic treatment of diseases associated with the modulation or inhibition of 11β-HSD1 in mammals. The invention further relates to pharmaceutical compositions of the novel compounds of the Formula (I) and methods for their use in the reduction or control of the production of cortisol in a cell or the inhibition of the conversion of cortisone to cortisol in a cell.
US08828978B2
The presently described technology provides compositions comprising aryl carboxylic acids chemically conjugated to hydrocodone (morphinan-6-one, 4,5-alpha-epoxy-3-methoxy-17-methyl) to form novel prodrugs/compositions of hydrocodone, including benzoates and heteroaryl carboxylic acids, which have a decreased potential for abuse of hydrocodone. The present technology also provides methods of treating patients, pharmaceutical kits and methods of synthesizing conjugates of the present technology.
US08828975B2
A phosphate-containing nanoparticle delivery vehicle includes a nanoparticle, an active ingredient, and a phosphodiester moiety connecting the nanoparticle and the active ingredient and forms a prodrug. The nanoparticle delivery vehicle achieves the function of increasing hydrophilicity of the active ingredient and specificity against tumor cells. Advantages of the nanoparticle material include biocompatibility, magnetism and/or controllable drug release.
US08828974B2
The present invention relates to a series of substituted 3-aminopropane phosphinic acid derivatives of formula I: wherein R, R1, P1, P2 and P3 are as defined herein. The compounds of this invention are useful in treating a variety of diseases including but not limited to depression, anxiety, certain psychiatric symptoms, cognitive impairment and schizophrenia.
US08828970B2
A method comprising administering an oligosaccharide composition to an organism having a gastrointestinal system to affect the production of GHG produced by the organism allowing for a reduction of the GHG produced by the organism while optimizing the health, feed intake, and protein synthesis of the organism so that management of the organism may realize the synergistic effects of maximizing both typical organism commodity-type concerns (e.g., size and production metrics) and atypical organism commodity-type concerns (e.g., carbon credit trading/monetization). A gas-reducing composition comprising soluble extractable material from a lignocellulosic source. A method of producing a composition, comprising providing a lignocellulosic source; extracting soluble materials from the lignocellulosic source to produce soluble extractable material; and processing the soluble extractable material to yield a gas-reducing composition, wherein the gas-reducing composition comprises hemicellulose and exhibits gas-reducing activity.
US08828962B2
No antiviral regimen has been consistently successful in treating H5N1 virus infection. We demonstrate that a group of highly effective siRNAs targeting different H5N1 viral genes shares a unique motif, GGAGU/ACUCC. We further demonstrate that the effectiveness of siRNAs containing this motif is not sequence specific. The results suggested that the structure of the unique motif is critical in determining the potency of siRNA-mediated protective effects against viral infection and this potent in vivo protection is associated with early productions of β-defensin and IL-6 induced by the motif. Provided are methods and prophylactic and therapeutic agents useful against other viral infections in addition to the H5N1 influenza virus.
US08828957B2
Provided are methods of generating an immune response to an antigen. The method comprises priming an individual by administering an expression vector encoding the antigen. The vectors comprises a transcription unit encoding a secretable fusion protein, the fusion protein containing an antigen and CD40 ligand. Administration of a fusion protein containing the antigen and CD40 ligand is used to enhance the immune response above that obtained by vector administration alone. The invention methods may be used to generate an immune response against cancer expressing a tumor antigen such as a mucin or human papilloma viral tumor antigen and to generate an immune response against an infectious agent. Also provided is a method for simultaneously producing the expression vector and the fusion protein.
US08828939B2
The present invention relates to modified cDNA sequences coding for vitamin K-dependent polypeptides, in particular human Factor VII, human Factor VIIa, human Factor IX and human protein C and their derivatives with improved stability and extended plasma half life, recombinant expression vectors containing such cDNA sequences, host cells transformed with such recombinant expression vectors, recombinant polypeptides and derivatives which do have biological activities of the unmodified wild type protein but having improved stability and processes for the manufacture of such recombinant proteins and their derivatives. The invention also covers a transfer vector for use in human gene therapy, which comprises such modified DNA sequences.
US08828937B2
The present invention is directed to an isolated peptide comprising or consisting of an amino acid sequence with an amino acid identity of at least 90% compared to mature human BMP2 with SEQ ID No. 1, characterized in that said amino acid sequence comprises at least two amino acid substitutions characterized in that a first amino acid substitution occurs at a position corresponding to N59, S88, E94, V99, K101 and/or N102 of SEQ ID No. 1 and to uses thereof.
US08828936B2
The present disclosure is generally related to methods of using the secretory protein SCGB3A2 for promoting lung development and treating lung disease. Some embodiments are, for example, methods for treating and inhibiting the development of neonatal respiratory distress. Other embodiments are methods of promoting lung development in damaged or diseased lungs. Also disclosed are methods for inhibiting lung damage due to anti-cancer agents.
US08828928B2
The inventions provided herein relate to amphiphilic peptides and particles comprising the amphiphilic peptides. Such amphiphilic peptides and particles described herein can be used as a delivery system, e.g., for therapeutic or diagnostic purposes, or as cell penetration vehicles or cell transfection agents.
US08828927B2
The present invention provides compositions for the therapeutic and/or cosmetic treatment of Elastin comprising tissues. Therapeutic and cosmetic compositions comprising an elastin digest stimulate the endogenous production of Elastin and appear to enhance the elasticity of the skin and provide an external supply of peptide precursors of Elastin that penetrate into the tissue to which it is applied. The present invention describes compositions containing an elastin digest derived from proteolytic digestion of insoluble elastin derived from mammalian ligaments with a protein digesting composition, such as proteinase K. The elastin digest is a mixture of elastin peptides wherein the elastin peptide mixture comprises peptides of the sequence GXXPG, wherein X represents one of the natural amino acids. The elastin digest of the present invention may also comprise epitopes of cytokines, growth factors and di-peptides. Methods of using these elastin digest comprising compositions for treating tissues in need of increased elasticity and or Elastin are described.
US08828919B2
A cleaning compound for cleaning surfaces that includes at least one container, with each container including a peroxide and/or an alkaline reactant therein. The alkaline reactant is selected to raise the pH of the cleaning compound into the alkaline range when the peroxide and the alkaline reactant are mixed together. The cleaning compound may be a liquid or dry compound, which is applied to the surface to be cleaned.
US08828916B2
The present invention relates to a process for preparing nonylated diphenylamines which improves nonene usage by recycling and reusing stripped nonene from an earlier process. The process comprising consecutive recycle of recovered nonene is conducted at a sequential two step temperature reaction, namely a more severe temperature followed by a lower temperature. The product prepared by this process is a useful antioxidant for lubricating oil compositions.
US08828914B2
A method of controlling or arresting the rate of depolymerization of a polymer composition during a biocide treatment by controlling the pH of the composition, and use of such methods in oilfield applications.
US08828907B2
The present invention relates to novel active compound combinations comprising, firstly, at least one known compound of the formula (I) in which R1 and A have the meanings given in the description and, secondly, at least one further known active compound from the class of the chitin synthesis inhibitors, the molting hormone agonists or other classes, which combinations are highly suitable for controlling animal pests such as insects and unwanted acarids.
US08828898B2
A glass plate made of soda lime silica glass containing at least MgO, CaO, Na2O and Al2O3 produced by a float process or a downdraw method, wherein [MgO] is at least 4.5%, [MgO]/[CaO] is larger than 1, and Q=([MgO]/[CaO])×([CaO]+[Na2O]−[Al2O3]) is at least 20, wherein [MgO] is the content of MgO, [CaO] is the content of CaO, [Na2O] is the content of Na2O, and [Al2O3] is the content of Al2O3 (each being as represented by mass percentage based on oxide) and a process for the glass plate.
US08828897B2
The invention relates to an alumino-silicate glass which has a thermal expansion coefficient in the range of 8 to 10×10−6/K in a temperature range of 20 to 300° C., a transformation temperature Tg in a range of 580° C. to 640° C., and a processing temperature VA in a range of 1065° C. to 1140° C. and which can therefore be used as an alternative for soda lime glasses. An object of the invention is also the use of the inventive glasses in applications where a high temperature stability of the glasses is advantageous, in particular as substrate glass, superstrate glass and/or cover glass in the field of semiconductor technology, preferably for Cd—Te or for CIS or CIGS photovoltaic applications and for other applications in solar technology.
US08828890B2
Provided is a method of depositing a cyclic thin film that can provide excellent film properties and step coverage. The method comprises the steps of forming a silicon thin film by repeating a silicon deposition step for depositing silicon on a substrate by injecting a silicon precursor into a chamber into which the substrate is loaded and a first purge step for removing a non-reacted silicon precursor and a reacted byproduct from the chamber; and forming the insulating film including silicon from the silicon thin film by forming a plasma atmosphere into the chamber.
US08828883B2
Apparatuses and methods for processing substrates are disclosed. A processing apparatus includes a chamber for generating a plasma therein, an electrode associated with the chamber, and a signal generator coupled to the electrode. The signal generator applies a DC pulse to the electrode with sufficient amplitude and sufficient duty cycle of an on-time and an off-time to cause events within the chamber. A plasma is generated from a gas in the chamber responsive to the amplitude of the DC pulse. Energetic ions are generated by accelerating ions of the plasma toward a substrate in the chamber in response to the amplitude of the DC pulse during the on-time. Some of the energetic ions are neutralized to energetic neutrals in response to the DC pulse during the off-time. Some of the energetic neutrals impact the substrate with sufficient energy to cause a chemical reaction on the substrate.
US08828875B1
Provided is a method of planarizing a semiconductor device. A dielectric layer is formed over a substrate. A plurality of openings is formed in the dielectric layer. The openings have varying distribution densities. The openings are filled with a metal material. A first chemical-mechanical-polishing (CMP) process is performed to remove portions of the metal material over the dielectric layer. Thereafter, a sacrificial layer is formed over the dielectric layer and the metal material. The sacrificial layer has a planar surface. The sacrificial layer is formed through one of: a spin-on process or a flowable chemical vapor deposition (FCVD) process. A second CMP process is then performed to remove the sacrificial layer and portions of the dielectric layer and the metal material therebelow. The second CMP process uses a slurry configured to have a substantially similar polishing selectivity between the sacrificial layer, the dielectric layer, and the metal material.
US08828870B2
A metal interconnect structure and a method of manufacturing the metal interconnect structure. Manganese (Mn) is incorporated into a copper (Cu) interconnect structure in order to modify the microstructure to achieve bamboo-style grain boundaries in sub-90 nm technologies. Preferably, bamboo grains are separated at distances less than the “Blech” length so that copper (Cu) diffusion through grain boundaries is avoided. The added Mn also triggers the growth of Cu grains down to the bottom surface of the metal line so that a true bamboo microstructure reaching to the bottom surface is formed and the Cu diffusion mechanism along grain boundaries oriented along the length of the metal line is eliminated.
US08828859B2
A microcrystalline semiconductor film is formed over a substrate using a plasma CVD apparatus which includes a reaction chamber in such a manner that a deposition gas and hydrogen are supplied to the reaction chamber in which the substrate is set between a first electrode and a second electrode; and plasma is generated in the reaction chamber by supplying high-frequency power to the first electrode. Note that the plasma density in a region overlapping with an end portion of the substrate in a region where the plasma is generated is set to be higher than that in a region which is positioned more on the inside than the region overlapping with the end portion of the substrate, so that the microcrystalline semiconductor film is formed over a region which is positioned more on the inside than the end portion of the substrate.
US08828858B2
Interlayer dielectric gap fill processes are enhanced by forming gate spacers with a tapered profile. Embodiments include forming a gate electrode on a substrate, depositing a spacer material over the gate electrode and substrate, the spacer layer having a first surface nearest the gate electrode and substrate, a second surface furthest from the gate electrode and substrate, and a continuously increasing etch rate from the first surface to the second surface, and etching the spacer layer to form a spacer on each side of the gate electrode. Embodiments further include forming the spacer layer by depositing a spacer material and continuously decreasing the density of the spacer material during deposition or depositing a carbon-containing spacer material and causing a gradient of carbon content in the spacer layer.
US08828856B2
Provided is a TFT substrate (10) on which vapor-deposited sections are to be formed by use of a vapor deposition device (50) which includes a vapor deposition source (85) having injection holes (86); and a vapor deposition mask (81) having opening (82) through which vapor deposition particles are deposited to form the vapor-deposited sections. The TFT substrate (10) includes pixels two-dimensionally arranged in a pixel region (AG); and wires (14) electrically connected to the respective pixels. The vapor-deposited sections (Q) are formed with gaps (X) therebetween, and the wires (14) having respective terminals that are disposed in the gaps (X).
US08828852B2
Systems and methods for producing high quantum efficiency silicon devices. A silicon MBE has a preparation chamber that provides for cleaning silicon surfaces using an oxygen plasma to remove impurities and a gaseous (dry) NH3+NF3 room temperature oxide removal process that leaves the silicon surface hydrogen terminated. Silicon wafers up to 8 inches in diameter have devices that can be fabricated using the cleaning procedures and MBE processing, including delta doping.
US08828845B2
Provided is a method of fabricating an oxide thin film device using laser lift-off and an oxide thin film device fabricated by the same. The method includes: forming an oxide thin film on a growth substrate; bonding a temporary substrate on the oxide thin film; irradiating laser onto the growth substrate to separate the oxide thin film on which the temporary substrate has been bonded from the growth substrate; bonding a device substrate on the oxide thin film on which the temporary substrate has been bonded; and forming an upper electrode film on the oxide thin film. Therefore, it is possible to overcome problems caused by a defective layer by transferring an oxide thin film transferred on a polymer-based temporary substrate onto a device substrate, without using an interface on which a defective layer formed due to oxygen diffusion upon laser lift-off is formed.
US08828838B2
An integrated circuit device and methods of manufacturing the same are disclosed. In an example, integrated circuit device includes a capacitor having a doped region disposed in a semiconductor substrate, a dielectric layer disposed over the doped region, and an electrode disposed over the dielectric layer. At least one post feature embedded in the electrode.
US08828829B2
A method for fabricating a semiconductor device includes forming a plurality of bit line structures over a substrate, forming contact holes between the bit line structures, forming sacrificial spacers on sidewalls of the contact holes, forming first plugs recessed inside the contact holes, forming air gaps by removing the sacrificial spacers, forming conductive capping layers capping the first plugs and the air gaps, and forming second plugs over the conductive capping layers.
US08828823B2
A semiconductor device and method for fabricating a semiconductor device is disclosed. An exemplary semiconductor device includes a substrate including a fin structure including one or more fins disposed on the substrate. The semiconductor device further includes a dielectric layer disposed on a central portion of the fin structure and traversing each of the one or more fins. The semiconductor device further includes a work function metal disposed on the dielectric layer and traversing each of the one or more fins. The semiconductor device further includes a strained material disposed on the work function metal and interposed between each of the one or more fins. The semiconductor device further includes a signal metal disposed on the work function metal and on the strained material and traversing each of the one or more fins.
US08828818B1
Methods of fabricating integrated circuit device with fin transistors having different threshold voltages are provided. The methods may include forming first and second semiconductor fins including first and second semiconductor materials, respectively, and covering at least one among the first and second semiconductor fins with a mask. The methods may further include depositing a compound semiconductor layer including the first and second semiconductor materials directly onto sidewalls of the first and second semiconductor fins not covered by the mask and oxidizing the compound semiconductor layer. The oxidization process oxidizes the first semiconductor material within the compound semiconductor layer while driving the second semiconductor material within the compound semiconductor layer into the sidewalls of the first and second semiconductor fins not covered by the mask.
US08828813B2
The present disclosure relates to a device and method for strain inducing or high mobility channel replacement in a semiconductor device. The semiconductor device is configured to control current from a source to a drain through a channel region by use of a gate. A strain inducing or high mobility layer produced in the channel region between the source and drain can result in better device performance compared to Si, faster devices, faster data transmission, and is fully compatible with the current semiconductor manufacturing infrastructure.
US08828808B2
A photoelectric conversion apparatus includes: an active matrix-type TFT array substrate on which photoelectric conversion elements and thin film transistors are arranged in a matrix shape, wherein the photoelectric conversion element connects with a drain electrode via a contact hole opened through a first interlayer insulation film provided above the thin film transistor, wherein a data line and a bias line are connected with the source electrode and the photoelectric conversion element via respective contact holes opened through the second interlayer insulation, and wherein at least a part of the photoelectric conversion element is fixed to have a shape different from a normal pixel between pixels adjacent to each other in an extending direction of the gate line, and an electrical connection between the photoelectric conversion element and the data line is cut off in the transistor of the pixel having the different shape.
US08828792B2
Disclosed herein are methods for assembling nanostructures. The assembling methods include contacting the plurality of nanostructures to a substrate having one or more discontinuities. At least a portion of the plurality of nanostructures assemble adjacent to the discontinuity, the assembled nanostructures including at least one nanostructure having a bridging, molecule. Devices, such as field-effect transistors, are also disclosed.
US08828782B2
Processes for making a solar cell by depositing various layers of components on a substrate and converting the components into a thin film photovoltaic absorber material. Processes of this disclosure can be used to control the stoichiometry of metal atoms in making a solar cell for targeting a particular concentration and providing a gradient of metal atom concentration. A selenium layer can be used in annealing a thin film photovoltaic absorber material.
US08828777B2
The present invention discloses a wafer level image sensor packaging structure and a manufacturing method of the same. The manufacturing method includes the following steps: providing a silicon wafer, dicing the silicon wafer, providing a plurality of transparent lids, fabricating a plurality of semi-finished products, performing a packaging process, mounting solder balls, and cutting an encapsulant between the semi-finished products. The manufacturing method of the invention has the advantage of being straightforward, uncomplicated, and cost-saving. Thus, the wafer level image sensor package structure is lightweight, thin, and compact. To prevent the image sensor chip from cracking on impact during handling, the encapsulant will be arranged on the lateral sides of the semi-finished products during the packaging process.
US08828774B2
Herein disclosed is a method of forming a thermoelectric material having an optimized stoichiometry, the method comprising: reacting a precursor material including a population of nanocrystals with a first ionic solution and a second ionic solution to form a reacted mixture.
US08828766B2
A light-emitting device and a method of fabricating the same, in which the light emission characteristics of the light-emitting device in the UV range are maximized such that a high-efficiency light-emitting device can be produced at low cost. For this, the method includes the step of forming a zinc oxide light-emitting layer on a base substrate, the zinc oxide light-emitting layer including zinc oxide doped with a dopant; and activating the dopant by rapidly heat-treating the zinc oxide light-emitting layer, so that light emission in an ultraviolet range is increased.
US08828742B2
A method of manufacturing a magnetoresistive effect element includes forming a first electrode above a substrate, forming a metal layer of a metal material above the first electrode, forming a first magnetic layer above the metal layer, forming a tunnel insulating film above the first magnetic layer, forming a second magnetic layer above the tunnel insulating film, forming a second electrode layer above the second magnetic layer, patterning the second electrode layer, patterning the second magnetic layer, the tunnel insulating film, the first magnetic layer and the metal layer, while depositing sputtered particles of the metal film on side walls of the second magnetic layer, the tunnel insulating film, the first magnetic layer and the metal layer to form a sidewall metal layer, and oxidizing the sidewall metal layer to form an insulative sidewall metal oxide layer.
US08828739B2
Rapid lateral flow immunoassays have an extensive history of use in both the clinical and home settings. These devices are used to test for a variety of analytes, such as drugs of abuse, hormones, proteins, urine or plasma components and the like. The present invention provides an improved procedural control that indicates to the test user that at least a portion of the applied sample has passed through the test result zone of the test strip, and optionally that the test is complete and the test results may be read.
US08828736B2
We have developed an microelectroporation device that combines microarrays of oligonucleotides, microfluidic channels, and electroporation for cell transfection and high-throughput screening applications (e.g. RNA interference screens). Microarrays allow the deposition of thousands of different oligonucleotides in microscopic spots. Microfluidic channels and microwells enable efficient loading of cells into the device and prevent cross-contamination between different oligonucleotides spots. Electroporation allows optimal transfection of nucleic acids into cells (especially hard-to-transfect cells such as primary cells) by minimizing cell death while maximizing transfection efficiency. This invention has the advantage of a higher throughput and lower cost, while preventing cross-contamination compared to conventional screening technologies. Moreover, this device does not require bulky robotic liquid handling equipment and is inherently safer given that it is a closed system.
US08828732B2
The method of labeling a sugar chain from a biological sample employs a single reaction vessel for the sequential performance of the following steps of (a) isolating a sugar chain from a sample using a sugar-trapping substance; (b) washing the sugar-trapping substance having the sugar chains trapped thereon; (c) releasing the sugar chain from the sugar-trapping substance; and (d) labeling the released sugar chain with UV/visible or fluorescent compound having an amino group forming a stable labeled sugar in fewer steps than a conventional ion exchange based technique.
US08828730B2
Disclosed is a method for measuring thrombin generation in a whole blood sample. The whole blood sample may be applied forthwith, without prior processing. The blood cells and blood plasma in the whole blood sample are separated by (lateral) flow migration. Also disclosed is an assembly of a sample support and a device dedicated to measure thrombin generation in a whole blood sample. Advantageously, the sample support comprises a separator medium allowing separation of whole blood into blood cells and blood plasma by means of (lateral) flow migration.
US08828725B2
A culture medium is used for culturing neural cells. Each neural cell includes a neural cell body and at least one neurite branched from the neural cell body. The culture medium includes a substrate and a carbon nanotube structure located on the substrate. The carbon nanotube structure includes a number of carbon nanotube wires spaced apart from each other. A distance between adjacent carbon nanotube wires is greater than or equal to diameters of the neural cell bodies. The carbon nanotube wires are capable of guiding extending directions of the neurites.
US08828721B1
The present invention provides a method of inducing myelination of isolated motoneurons by preparing a non-biological substrate having thereon a covalently attached monolayer of DETA; depositing isolated motoneurons on the substrate in a defined serum-free medium; plating isolated Schwann cells cultured in the defined serum-free medium onto the motoneurons, thereby initiating a co-culture; and passaging the co-culture as necessary into fresh, defined serum-free medium supplemented with L-ascorbic acid at least until the motoneurons form Nodes of Ranvier indicative of myelination. The invention also includes a method of testing for new drugs effective in demyelinating diseases. Additionally, cellular products provided by the invention include an isolated motoneurons myelinated or remyelinated in vitro according to the methods disclosed.
US08828718B2
The present invention relates to a gene transfer vector (GTV) and in particular to an integrating gene transfer vector (IGTV), which comprises at least one genetic insulator element (GIE), wherein the each comprises at least two copies of an element selected from the group consisting of: a CTF binding site; a first CTCF binding site and a second CTCF binding site, wherein the first and the second CTCF binding sites are derived from the regulatory sequences of different genes.
US08828715B2
A method for characterizing particle adhesion in microfluidic bifurcations and junctions comprises at least one idealized bifurcation or junction. Multiple bifurcations and/or junctions can be combined on a single microfluidic chip to create microfluidic networks configured for assays specifically to characterize particle interactions at junctions or to screen particles for desired interactions with microfluidic bifurcations and/or junctions.
US08828699B2
Disclosed are: a eukaryotic amadoriase which is prepared by introducing a mutation into DNA encoding a eukaryotic amadoriase derived from a microorganism belonging to the genus Coniochaeta or Eupenicillium so as to introduce a substitution into a specific amino acid residue in the eukaryotic amadoriase, thereby overcoming the defect associated with thermal stability; a gene or recombinant DNA for the eukaryotic amadoriase; and a process for production of a eukaryotic amadoriase having excellent thermal stability.
US08828688B2
Compositions and methods for amplifying selected polynucleotides, including DNA and RNA, particularly in multiplex amplification reactions using common primers amplification. Generally, methods of the invention employ multiple steps such as template-specific hybridization, a linear amplification, partial degradation of nucleic acid, and ligation. At the end of the process the sequences of selected polynucleotides are flanked by the common sequences which can be used for exponential amplification using common primers. In some aspects the polynucleotides are associated with a barcode and the presence of the barcode is detected to measure the amount of the polynucleotide.
US08828686B2
The invention relates to mammalian PAI-I ligands and modulators. In particular, the invention relates to polypeptides, polypeptide compositions and polynucleotides that encode polypeptides that are ligands and/or modulators of PAI-I. The invention also relates to polyligands that are homopolyligands or heteropolyligands that modulate PAI-I activity. The invention also relates to ligands and polyligands localized to a region of a cell. The invention also relates to localization tethers and promoter sequences that can be used to provide spatial control of the PAI-I ligands and polyligands. The invention also relates to inducible gene switches that can be used to provide temporal control of the PAI-I ligands and polyligands. The invention also relates to methods of treating or preventing atherosclerosis. The invention also relates to methods of treating or preventing fibrosis.
US08828685B2
Isolated monomelic aminoacyl-tRNA synthetase polypeptides and polynucleotides having non-canonical biological activities are provided, as well as compositions and methods related thereto.
US08828679B2
Disclosed is a method for detecting a biological signal of a three-dimensional cell culture construct. The method for detecting a biological signal of a three-dimensional cell culture construct includes: providing a three-dimensional cell culture construct that contains at least two cell layers laminated to each other and a sensor particle capable of detecting a biological signal; and observing the sensor particle optically. Preferably, the three-dimensional cell culture construct contains an extracellular matrix including a combination of a protein or polymer having an RGD sequence and a protein or polymer that interacts with the protein or polymer having the RGD sequence, or a combination of a protein or polymer that is positively charged and a protein or polymer that is negatively charged.
US08828672B2
PARylated proteins are enriched by treating cell lysates comprising PARylated proteins and DNA/RNA with an endonuclease that cleaves the DNA/RNA but not the PAR; and separating the PARylated proteins from the cleaved DNA/RNA. PARylation sites are labeled by eluting PARylated proteins from a PAR-affinity substrate with a nucleophilic amine exchange reactant, wherein the reactant labels PARylation sites of the proteins. Specific binding agents are identified by screening compounds for specific binding to a PARylated protein disclosed herein; and identifying one of the compounds as a specific binder of the protein. Antibodies which specifically bind PARylation sites are also disclosed.
US08828664B2
Sample preparation processes for in situ RNA or DNA analysis, methods and compositions therefor are provided. Processes provided herein allow DNA or RNA analysis to be carried out in the same tube or on an aliquot of the prepared sample without centrifugation or extraction. The preparation process can be carried out at room temperature in as little as seven minutes and is amenable to high throughput processing using manual or robotic platforms.
US08828655B2
A method is provided for conducting a droplet-based enzymatic assay, e.g., for diagnostic purposes. On a droplet actuator, a droplet comprising an enzyme of interest is provided along with a droplet comprising a substrate which is potentially modified in the presence of the enzyme. Droplet operations are executed to combine the enzyme and substrate droplets on the droplet actuator, thereby yielding an assay droplet on the droplet actuator. Detecting modification of the substrate by the enzyme in the assay droplet occurs on the droplet actuator. Modified substrate preparations for conducting such enzymatic assays are also provided.
US08828654B2
A receptacle having a plurality of interconnected chambers arranged to permit multiple process steps or processes to be performed independently or simultaneously. The receptacles are manufactured to separate liquid from dried reagents and to maintain the stability of the dried reagents. An immiscible liquid, such as an oil, is included to control loading of process materials, facilitate mixing and reconstitution of dried reagents, limit evaporation, control heating of reaction materials, concentrate solid support materials to prevent clogging of fluid connections, provide minimum volumes for fluid transfers, and to prevent process materials from sticking to chamber surfaces. The receptacles can be adapted for use in systems having a processing instrument that includes an actuator system for selectively moving fluid substances between chambers and a detector. The actuator system can be arranged to concentrate an analyte present in a sample. The detector can be used to detect an optical signal emitted by the contents of the receptacle.
US08828650B2
A method for making a retarder includes: (a) forming a photocurable layer on a substrate, the photocurable layer including at least one photocurable prepolymer that has a plurality of reactive functional groups and a functional group equivalent weight ranging from 70 to 700 g/mol; (b) covering partially the photocurable layer using a patterned mask; (c) exposing the photocurable layer through the patterned mask; (d) removing the patterned mask; (e) exposing the photocurable layer to cure second regions of the photocurable layer so as to form a microstructure; (f) forming an alignment layer on the microstructure; (g) forming a liquid crystal layer on the alignment layer; and (h) curing the liquid crystal layer.
US08828645B2
There is disclosed a negative resist composition comprising at least: (A) a base polymer that is alkaline-soluble and is made alkaline-insoluble by action of an acid; (B) an acid generator; and (C) a basic component, wherein the base polymer at least contains a polymer including repeating units represented by the following general formula (1) and general formula (2) and having a weight average molecular weight of 1,000 to 10,000. There can be a negative resist composition hardly causing a bridge in forming a pattern and providing a high resolution and a patterning process using the same.
US08828641B2
A chemically amplified resist composition comprising a base polymer, an acid generator, and a basic compound of thiomorpholine dioxide structure has many advantages including a high contrast of alkaline dissolution rate before and after exposure, a good pattern profile after exposure, minimized roughness, and a wide focus margin. The resist composition which may be positive or negative is useful for the fabrication of VLSI and photomasks.
US08828640B2
This invention relates to a photo-curing polysiloxane composition including a polysiloxane, a quinonediazidesulfonic acid ester, a methylene alkoxyaryl-containing compound as a curing agent, and a solvent for dispersing the polysiloxane, the quinonediazidesulfonic acid ester, and the methylene alkoxyaryl-containing compound. This invention also provides a protecting film made from the photo-curing polysiloxane composition, and an element containing the protecting film.
US08828639B2
The invention provides a toner that is capable of low-temperature fixing even in high-speed electrophotographic processes while keeping the cleaning performance when used at high temperatures and the high-temperature storage stability. This toner having toner particles, each of which contains a binder resin and a colorant is characterized in that the temperature of Tp [° C.] when the loss elastic modulus obtained by dynamic viscoelastic measurements on the toner exhibits a maximum value in the temperature range from at least 30° C. to not more than 200° C., is from at least 40° C. to not more than 55° C., and in that, with G″(Tp) [Pa] being this maximum value, G″(Tp+15) [Pa] being the loss elastic modulus at the temperature of Tp+15 [° C.], and G″(Tp+30) [Pa] being the loss elastic modulus at the temperature of Tp+30 [° C.], G″(Tp), G″(Tp+15), and G″(Tp+30) satisfy prescribed relationships.
US08828638B2
A two-component developer including a yellow toner and a carrier, the yellow toner including at least one of C. I. Pigment Yellow 155 or C. I. Pigment Yellow 185, and an azo pigment, the carrier including a first resin, magnetic particles dispersed in the first resin, and elements of Cu, Zn, Ni and Mn each in an amount of from 0 to about 2,000 ppm.
US08828637B2
Toner particles are provided which may include a core and a shell, one or both of which may include a polyester gel. The gel in the shell and/or core may prevent a crystalline resin in the core from migrating to the toner surface.
US08828621B2
A fuel cell module may include a membrane electrode assembly, two gas diffusion layers, two current collectors, two sealing members, a fluid flow plate assembly. The fluid flow plate assembly may include a first manifold, a second manifold, and a fluid flow channel. The membrane electrode assembly may include at least one membrane for fuel cell reactions. The two gas diffusion layers may be respectively coupled with two opposite sides of the membrane electrode assembly. The two current collectors respectively coupled with the two gas diffusion layers, and the two sealing members respectively coupled with the two current collectors. The fluid flow plate assembly may be coupled with the membrane electrode assembly at a first side of the two opposite sides of the membrane electrode assembly, with at least a corresponding one of the two gas diffusion layers, at least a corresponding one of the two current collectors, and at least a corresponding one of the two sealing members coupled between the fluid flow plate assembly and the first side of the membrane electrode.
US08828614B2
The present invention provides a fuel cell hybrid system having a multi-stack structure, which maintains the voltage of a fuel cell at a level lower than that of an electricity storage means (supercapacitor) during regenerative braking so that the fuel cell does not unnecessarily charge the electricity storage means, thereby increasing the amount of recovered energy and improving fuel efficiency.
US08828606B2
A positive electrode active material includes: a complex oxide particle containing at least lithium and one or plural transition metals; and a coating layer provided in at least a part of the complex oxide particle, wherein the coating layer contains at least one element M which is different from the principal transition metal constituting the complex oxide particle and which is selected among elements belonging to the Groups 2 to 13, and at least one element X selected among phosphorus (P), silicon (Si) and germanium (Ge), and the element M and the element X show different distribution from each other in the coating layer.
US08828603B2
A secondary battery includes: an electrolytic solution; a positive electrode; and a negative electrode, at least one of the positive electrode, the negative electrode, and the electrolytic solution containing an alkyl carbonate represented by the following formula (1) R—O—C(═O)—O—X (1) wherein R is a linear alkyl group or halogenated alkyl group having a carbon number of from 8 to 20, or a branched alkyl group or halogenated alkyl group having a carbon number of from 8 to 20 in a main chain thereof; and X is an alkali metal element.
US08828597B2
A non-aqueous electrolyte battery comprising: a battery case containing aluminum; a positive electrode terminal attached to the battery case; and a negative electrode terminal attached to the battery case and insulated from the battery case, wherein the positive electrode terminal and the battery case are connected through a resistor having resistance of 1Ω to 1 MΩ. Otherwise, A non-aqueous electrolyte battery comprising: a battery case containing iron; a negative electrode terminal attached to the battery case; and a positive electrode terminal attached to the battery case and insulated from the battery case, wherein the negative electrode terminal and the battery case are connected through a resistor having resistance of 1Ω to 1 MΩ.
US08828596B2
A secondary battery, including an electrode assembly including a first electrode, a second electrode, and a first electrode tab and a second electrode tab connected to the first electrode and the second electrode, respectively; a case including a receiving part that receives the electrode assembly, the case having an open side; a cap plate sealing the open side of the case; and a first electrode terminal and a second electrode terminal passing through the cap plate, the first electrode terminal being connected to the first electrode tab, the second electrode terminal being connected to the second electrode tab, the first electrode terminal including a first terminal, a lower terminal plate provided at a top end of the first terminal, and an upper terminal plate provided at a top end of the lower terminal plate, the first electrode tab being connected to a bottom end of the first terminal.
US08828594B2
A battery pack that includes a bare cell, a bottom case and a resin part disposed on a lower surface of the bare cell. The bottom case has a number of holes. The resin part is disposed on a surface of the bare cell affixing the bottom case to the bare cell. Further, a number of protrusions is provided and composed of the same material as the resin part in which each protrusion corresponds to a hole. The protrusions and the holes have a circular, tetragonal or polygonal cross sectional shape in which upon thermal compression of the protrusions the bottom case is solidly coupled to the resin part.
US08828584B2
A lithium-ion rechargeable battery module having a plurality of lithium-ion battery cells, arranged that battery cells located at an high temperature portion of the module are electrically connected in parallel with battery cells located at a low temperature portion of the module. The battery cells at the high temperature portion have a higher electric resistance at 20° C. and a better high-temperature storage characteristic at 50° C. than those of the battery cells located at the low temperature portion.
US08828574B2
Provided are lithium sulfur battery cells that use water as an electrolyte solvent. In various embodiments the water solvent enhances one or more of the following cell attributes: energy density, power density and cycle life. Significant cost reduction can also be realized by using an aqueous electrolyte in combination with a sulfur cathode. For instance, in applications where cost per Watt-Hour (Wh) is paramount, such as grid storage and traction applications, the use of an aqueous electrolyte in combination with inexpensive sulfur as the cathode active material can be a key enabler for the utility and automotive industries, providing a cost effective and compact solution for load leveling, electric vehicles and renewable energy storage.
US08828569B2
Disclosed is a battery can for a storage battery, provided with a safety valve having a first and a second score groove portion is provided to inner and outer surface of can bottom, can body, or can lid. The first and the second score groove portion face each other, and have a first and a second score groove bottom portion, which have a radius of curvature R, respectively. The R is more than 0.20 mm and less than 1.20 mm, and a distance between the bottom portions is 0.045 to 0.150 mm. The portion, which has the safety valve, is constituted by a plated steel sheet having a steel sheet portion of C content is less than 0.040 mass %, S content is less than 0.020 mass %, and tensile strength TS is less than 400 MPa, and a plate layer formed on a surface of the steel sheet portion.
US08828567B2
A microbial power generation device includes an anode chamber which maintains a microbe and which is supplied with influent which includes an electron donor, a cathode chamber supplied with an electron acceptor, a nonconductive membrane having a first face and an opposing second face and arranged between the anode chamber and the cathode chamber, a first electro-conductive support material having a rough surface which has asperity spreading close to the first face of the nonconductive membrane, and formed by a porous material having approximately the same shape as the interior of the anode chamber, and arranged within the anode chamber, and a second electro-conductive support material having a rough surface which has asperity spreading close to the second face of the nonconductive membrane.
US08828563B2
A cutting tool for metal material processing has a hard metal body and a multi-layer coating applied to the hard metal body in at least one surface area. The multi-layer coating includes the following, sequentially in direction from the hard metal body to the surface of the cutting tool: at least one layer TiCx1Ny1, where x1+y1=1, x1≧0, y1>0; at least one layer TiCx2Ny2Oz2, where x2+y2+z2=1, 0≦z2≦0.03 and 0.5≦x2≦0.85; at least one layer TiN, or TiCx31Ny31, where 0.2≦x31≦0.8 and x31+y31=1, or TiNy32Bv32, where 0.0001≦v32≦0.05 and y32+v32=1; at least one layer: TiNy41Bv41Oz41, where y41+v41+z41=1 and 0.0001≦v41≦0.05 and 0.01≦z41≦0.6, or TiCx42Ny42Oz42, where x42+y42+z42=1 and 0≦y42≦0.5 and 0.01≦z42≦0.6; and at least one outer layer κ-Al2O3. The at least one layer TiCx2Ny2Oz2 has a texture in the direction having a texture coefficient TC(311)=1.3.
US08828562B2
The present invention provides hard coating film which excels conventional surface coating layer in wear resistance, has lower frictional coefficient and better slideability, a material coated with the hard coating film, a die for cold plastic working, and a method for forming the hard coating film. The hard coating film according to the present invention is a hard coating film comprising (NbxM1−x)y(BaCbN1−a−b)1−y, where 0.2≦x≦1.0 Equation (1) 0≦a≦0.3 Equation (2) 0≦1−a−b≦0.5 Equation (3) 0.5≦b=1 Equation (4) 0.4≦1−y≦0.9 Equation (5) [however, M denotes at least one species of elements belonging to Groups 4a, 5a, and 6a and Si and Al; x, 1−x, a, b, and 1−a−b represent respectively the atomic ratio of Nb, M, B, C and N; and y and 1−y represent respectively the ratio of (NbxM1−x) and (BaCbN1−a−b).]
US08828551B2
The general field of the invention is that of airbags. The invention relates to a process for improving the tear strength and the combing strength of coated fabrics intended for uses in the field of inflatable bags, using a silicone composition comprising an additive consisting of a polyorganosiloxane resin (V) and a calcium carbonate. After coating the composition onto the fabric supports and curing, the coated supports not only have optimum adhesion and crease resistance properties, but also have good properties in terms of combing strength and tear strength.
US08828547B2
A composition, preferably a halogen-free, flame retardant composition, comprising in weight percent based on the weight of the composition: A. 1 to 90% TPU polymer, B. 1 to 90% polyolefin polymer, preferably a polar polyolefin polymer, C. 1 to 60% phosphorus-based, intumescent flame retardant, D. 0.5 to 25% liquid phosphate modifier, e.g., bis-phenol-A-polyphosphate, and E. Optional additives and/or fillers. The compositions exhibit excellent strain and scratch whitening performance in combination with excellent burn performance, good flexibility and tensile properties, and good fabrication extrusion characteristics including improved surface smoothness.
US08828542B2
Nanoparticles can include a core linked to a polymerizable moiety that can be polymerized, cross-linked or cured. The polymerizable nanoparticles can be included in a composition for a polymerization, cross-linking or curing reaction in an amount and disposition sufficient for inhibiting or preventing volume shrinkage during polymerization, cross-linking or curing reaction. Also, the nanoparticles can be included with monomers, dendrimers, oligomers or polymers in the compositions that can be reacted to form a polymerized, cross-linked or cured product.
US08828535B2
Provided is a cover tape that has a small range of stripping strength and generates little static electricity when stripped at a high speed. The cover tape according to the present invention comprises at least a substrate layer, an intermediate layer, a charge transfer layer, and a heat seal layer, characterized in that (A) the charge transfer layer containing an acid-modified polyolefin resin and a conductive agent, and (B) the heat seal layer containing (a) a thermoplastic resin component composed of an acrylic resin, and (b) a styrene-conjugated diene copolymer or a hydrogenated resin thereof, the mass ratio of the two components ((a)/(b)) being 20/80 to 80/20.
US08828528B2
A barrier film includes a base which is formed of a plastic film having a first surface and a second surface opposed to the first surface, a first barrier layer which is formed on the first surface by an atomic layer deposition method and is made of an inorganic material having a water vapor barrier property; and a second barrier layer which is formed on the second surface by an atomic layer deposition method and is made of an inorganic material having a water vapor barrier property.
US08828523B2
A method for manufacturing graphene using light capable of transferring and patterning graphene, and graphene manufactured using the method are disclosed. The method includes forming a graphene layer on a catalyst metal layer, attaching a support layer losing adhesion by light on the graphene layer, removing the catalyst metal layer, disposing a substrate on the graphene layer, and separating the support layer from the graphene layer by irradiating light to the support layer.
US08828520B2
As discussed herein, there is presented an apparatus comprising micro-posts. The apparatus includes a substrate having a planar surface, a plurality of micro-posts located on the planar surface, wherein each micro-post has a base portion on the planar surface and a post portion located on a top surface of the corresponding base portion, and wherein side surfaces of the base portions intersect the planar surface at oblique angles.
US08828519B2
A composition includes polymer and dispersed infrared-reflective clusters of titanium dioxide primary particles. The titanium dioxide primary particles are cemented together with precipitated silica and/or alumina to form clusters. The titanium dioxide primary particles have an average particle diameter in the range of from about 0.15 to about 0.35 micron, while the clusters of titanium dioxide primary particles have an average cluster diameter in the range of from about 0.38 to about 5 microns and a geometric standard deviation (GSD) in the range of from about 1.55 to about 2.5.
US08828517B2
A three-dimensional thin film solar cell (3-D TFSC) substrate having enhanced mechanical strength, light trapping, and metal modulation coverage properties. The substrate includes a plurality of unit cells, which may or may not be different. Unit cells are defined as a small self-contained geometrical pattern which may be repeated. Each unit cell structure includes a wall enclosing a trench. Further, the unit cell includes an aperture having an aperture diameter. A pre-determined variation in wall thickness, wall height, and aperture diameter among unit cells across the substrate produces specific advantages.
US08828513B2
An energy absorbing system has an inner tube and an outer tube that are stitched together. The inner tube contains a set of fibers oriented in a first direction and the outer tube has a second set of fibers oriented in a direction different from the first direction. Preferably these orientations are equal and opposite to each other. The inner tube may be hollow, but preferably has a cellular core. The outer tube may be spaced apart from the inner tube to create an annular cavity that is filled with a cellular material.
US08828511B2
The invention relates to a hollow glass article having, for a thickness of 5 mm, an overall light transmission greater than or equal to 70%, said overall light transmission being calculated by taking into consideration the illuminant C as defined by the ISO/CIE 10526 standard and the CIE 1931 standard colorimetric observer as defined by the ISO/CIE 10527 standard, and a filtering power greater than or equal to 65%, especially 70%, said filtering power being defined as being equal to the value of 100% reduced by the arithmetic mean of the transmission between 330 and 450 nm, said article having a chemical composition of soda-lime-silica type, which comprises the following optical absorbent agents in a content that varies within the weight limits defined below: Fe2O3 (total iron) 0.01 to 0.15% TiO2 0.5 to 3% Sulfides (S2−) 0.0010 to 0.0050%.
US08828510B2
A package with self-forming insulating walls includes a tray for supporting a food item, a flap joined to the tray along a fold line, and an insulating microwave material overlying at least a portion of the tray and at least a portion of the flap. The insulating microwave material may be joined to the flap. The insulating microwave material may include a microwave energy interactive material supported on a first polymer film layer, a moisture-containing layer joined to the microwave energy interactive material, and a second polymer film layer joined to the moisture-containing layer in a predetermined pattern, thereby defining a plurality of expandable cells between the moisture-containing layer and the second polymer film layer.
US08828497B2
A method for providing a metallic coat covering a surface is disclosed, which comprises: (i) applying an electrically conductive two component binder on said surface; (ii) electrostatic spraying a metal powder on the binder applied in step (i); wherein the metal powder comprises metal particles with an average diameter less than 80 micron.
US08828494B2
Disclosed are methods of treating a metal to improve the metal's corrosion resistance. In one such method, the method is carried out by applying, to the surface of the metal, a coating which includes magnesium powder and a UV-curable or other radiation-curable binder. In another such method, the method is carried out by applying, to the surface of the metal, a coating which includes magnesium powder and an inorganic binder. In another such method, a coating that includes a magnesium alloy powder and a binder is applied to the surface of the metal. The magnesium alloy powder is selected such that it has a corrosion potential that is from about 0.01 volt to about 1.5 volt more negative than the metal's corrosion potential. Also disclosed are methods of treating a ferrous metals and magnesium alloys to improve the corrosion resistance of these materials.
US08828493B2
Methods are disclosed for forming a layered structure comprising a self-assembled material. An initial patterned photoresist layer is treated photochemically, thermally, and/or chemically to form a treated patterned photoresist layer comprising a non-crosslinked treated photoresist. The treated photoresist is insoluble in an organic solvent suitable for casting a material capable of self-assembly. A solution comprising the material capable of self-assembly dissolved in the organic solvent is casted on the treated layer, and the organic solvent is removed. The casted material is allowed to self-assemble with optional heating and/or annealing, thereby forming the layered structure comprising the self-assembled material. The treated photoresist can be removed using an aqueous base and/or a second organic solvent.
US08828492B2
A method for making a coated article wherein the method includes the following steps: providing a substrate; and depositing an aluminum oxynitride coating layer from a gaseous mixture. The gaseous mixture contains the following components: 30.0-65.0 volume percent nitrogen, 0.7-1.3 volume percent aluminum tri-chloride; 1.0-2.0 volume percent ammonia, 0.1-1.5 carbon dioxide, 1.5-4.5 volume percent hydrogen chloride, optional components of carbon monoxide and/or argon, and hydrogen as the balance.
US08828485B2
We disclose novel metallic nanoparticles coated with a thin protective carbon shell, and three-dimensional nano-metallic sponges; methods of preparation of the nanoparticles; and uses for these novel materials, including wood preservation, strengthening of polymer and fiber/polymer building materials, and catalysis.
US08828482B1
A disk for a hard disk drive is provided. The disk comprises a substrate comprising aluminum, and a coating layer disposed over the substrate. The coating layer comprises an alloy of Ni, X1 and X2, wherein X1 comprises one or more elements selected from the group consisting of Ag, Au, B, Cr, Cu, Ga, In, Mn, Mo, Nb, Pb, Sb, Se, Sn, Te, W, Zn and Zr, and wherein X2 comprises either B or P, and wherein X1 and X2 do not comprise the same elements.
US08828477B2
A deposition mask and a display unit and method of manufacturing same are provided. A red continuous organic layer, a green continuous organic layer, and a blue continuous organic layer are provided over two or more lines of a matrix configuration of organic light emitting devices in common. A film thickness distribution in the extensional direction of the red, green and blue continuous organic layer is dissolved, and an aperture ratio can be improved by just that much.
US08828473B2
Suggested are substance mixtures, containing (a) at least one starch derivative and (b) at least one bitter principle and optionally (c) stabilizers, characterized in that components (a) and (b) are present in a weight ratio of from 1000:1 to 1:1.
US08828470B2
A food or beverage composition suitable for human consumption includes an aqueous suspension such as cow's milk that has been supplemented and homogenized with an omega-3 fatty acid-containing supplementation oil, in which a supplementation oil includes one part by weight of an EPA/DHA fatty acid-containing enriching oil that has been combined and diluted with at least one part by weight of an oxidative stabilization oil, such as a low linoleic acid/high oleic acid-containing oxidative stabilization oil. As a result, the rate of oxidation of EPA/DHA fatty acids added to the aqueous suspension via the supplementation oil can be reduced at least two-fold or even much more compared to the rate of oxidation of an equal quantity of the same EPA/DHA fatty acid-containing enriching oil homogenized into the same aqueous suspension without having been first combined and diluted with the oxidative stabilization oil.
US08828469B2
An individual alkamide and/or a mixture having two or more different alkamides, is disclosed for changing, masking or reducing the unpleasant flavor impression of an unpleasant-tasting substance or mixture of substances. The alkamide can be trans-pellitorine; cis-pellitorine; 2Z,4Z- or 2Z,4E-decadienoic acid-N-isobutylamide; 2E,4E-decadienoic acid-N-([2S]-2-methylbutyl)amide; 2E,4E-decadienoic acid-N-([2R]-2-methylbutylamide); 2E,4Z-decadienoic acid-N-(2-methylbutyl)amide; achilleamide; sarmentine; 2E- or 3E-decenoic acid-N-isobutylamide; 3E-nonenoic acid-N-isobutylamide; spilanthol; homospilanthol; 2E,6Z,8E-decatrienoic acid-N-([2R]-2-methylbutyl)amide; 2E- or 2Z-decen-4-oic acid-N-isobutylamide; α-sanshool; α-hydroxysanshool; γ-hydroxysanshool; γ-hydroxysanshool; γ-hydroxyisosanshool; γ-dehydrosanshool; γ-sanshool; bungeanool; isobungeanool; dihydrobungeanool; or tetrahydrobungeanool, or combinations thereof.
US08828463B2
Packaging of bananas in containers, for example polyethylene bags, having designed permeabilities to oxygen, carbon dioxide, and ethylene. The bags preferably include a gas-permeable membrane comprising (1) a microporous film, and (2) a polymeric coating on the microporous film. The containers enable storage and/or ripening of bananas under controlled conditions. Using the new containers, bananas can be ripened while they are being transported, or in conventional ripening rooms without opening the containers in which they have been transported, or after they have left a ripening room. In addition, bananas can be preserved in a satisfactory ripened state for longer periods of time.
US08828455B2
Disclosed are cosmetic toner formulations and methods for their use comprising botanical plant extracts and a cosmetic vehicle.
US08828454B2
The present invention concerns a base characterized in that it is prepared by the following steps: (a) partial bio-hydrolysis of raw materials rich in precursors, and (b) thermal reaction steps of the resulting product from (a). Said base can be prepared with a further step, which is a subsequent or simultaneous fermentation of the resulting product from step (a).
US08828453B2
Aspects of the invention relate to compositions comprising passiflora extracts that may improve neurological and behavioral symptoms associated with Pervasive Developmental Disorders.
US08828451B2
Most human tumors find ways to resist anticancer drug monotherapy. Akt is considered a likely peptide providing such monotherapy drug resistance. Data indicates that Akt chemoresistance is induced in a p53-dependent manner and that inhibition of Akt may be an effective means of overcoming chemoresistance in cancer cells expressing wild-type p53. Breast, ovarian, lung cancer and leukemia cells lines were treated with combinations of Akt activation inhibitor Triciribine (TCN) or Triciribine phosphate (TCNP) and chemotherapeutic drugs to determine the efficiency of combination therapy. Additionally, cells were introduced into xenograft models to determine in vivo effects of combination treatment. Combining TCN or TCNP with other anticancer drugs overcame cytotoxic or treatment resistance. Thus, TCN and TCNP are shown to broaden the spectrum of human tumors that can be effectively treated.
US08828450B2
The present invention relates to a composition for use against one or more pathogens, comprising at least one antagonistic micro-organism and at least one salt and/or derivatives thereof as defined in claim 1. The present invention further relates to said composition for use as biopesticide.
US08828448B2
The invention provides an improved method of producing a natural, acellular matrix scaffold for subsequent use in tissue-engineered replacement of tissues such as the bladder. Decellularization is carried out on an expanded or distended bladder and the product retains the strength and compliance of natural material. The invention also provides use of the matrix scaffolds as wound healing material and to investigate tissue structure and function in vitro.
US08828447B2
The present invention relates to processes for the isolation of a phospholipid and for producing a polyunsaturated, long-chain fatty acids (PUFA)-enriched fraction from a fish oil comprising the steps of —providing a fish oil containing lipids and phospholipids; —mixing the fish oil with a polar solvent; —centrifuging the mixture of the fish oil and the polar solvent to separate a polar fraction from a lipid fraction; —isolating a phospholipid from the polar fraction or isolating a PUFA-enriched fraction from the polar fraction. The fish oil may be provided by —extracting a fish material with an extractant solvent; —removing the extractant solvent to provide the fish oil; —optionally subjecting the fish oil to a solid-liquid separation. The isolated phospholipids and PUFA's may be used as additives for functional foods, as a dietary supplement and for pharmaceutical application.
US08828432B2
Controlled release, discrete, solid particles which contain an encapsulated and/or embedded component such as a heat sensitive or readily oxidizable pharmaceutically, biologically, or nutritionally active component are continuously produced without substantial destruction of the matrix material or encapsulant. A release-rate controlling component is incorporated into the matrix to control the rate of release of the encapsulant from the particles. The additional component may be a hydrophobic component or a high water binding capacity component for extending the release time. The plasticizable matrix material, such as starch, is admixed with at least one plasticizer, such as water, and at least one release-rate controlling component under low shear mixing conditions to plasticize the plasticizable material without substantially destroying the at least one plasticizable material and to obtain a substantially homogeneous plasticized mass. The plasticizer content is substantially reduced and the temperature of the plasticized mass are substantially reduced prior to admixing the plasticized mass with the encapsulant to avoid substantial destruction of the encapsulant and to obtain a formable, extrudable mixture. The mixture is extruded through a die without substantial or essentially no expansion and cut into discrete, relatively dense particles. Release properties may also be controlled by precoating the encapsulant and/or coating the extrudate particles with a film-forming component.
US08828429B2
The present invention relates to a controlled release capsule preparation for oral administration, which contains (i) a granule containing a physiologically active substance which is a compound represented by the formula: wherein n is an integer of 1 to 3, and Ar is an aromatic ring optionally having substituent(s), or a salt thereof, and a hydrophilic polymer, and coated with an enteric coating agent and the like, and (ii) a fluidizer. According to the present invention, a controlled release composition for oral administration of an imidazole derivative, which has steroid C17,20-lyase inhibiting activity and which has remarkably improved sustainability of the blood concentration, is provided.
US08828417B2
For an implantable device intended for use in the human body an in-vivo colonization with autologous cells is often desired. The devices, especially prosthetic devices like implant tissues, grafts, shunts, vessels, organs or a part of organs are commonly derived from animal or human origin and comprise a collagen-based tissue matrix. The invention proposes a coating deposited on a surface of the device and comprising the matrix protein CCN1 as an extracellular matrix-associated protein mediating cell adhesion or cell migration.
US08828409B2
A method for immunizing a human or animal against pneumococcal infections, comprising by administering a vaccine comprising a purified recombinant caseinolytic protease P (ClpP) protein of S. pneumoniae in an immunologically effective amount to the human or animal.
US08828406B2
Described herein are chimeric influenza virus gene segments and nucleic acid sequences encoding such chimeric influenza virus gene segments. A chimeric influenza virus gene segment described herein comprises packaging signals found in the non-coding and coding regions of one type of influenza virus gene segment and an open reading frame of a different type of influenza virus gene segment or fragment thereof. Also described herein are recombinant influenza viruses comprising two or more chimeric influenza virus gene segments and the use of such viruses in the prevention and/or treatment of influenza virus disease.
US08828397B2
Immunoglobulin chains or antibodies having light or heavy chain complementarity determining regions of antibodies that bind to P-Selectin Glycoprotein Ligand-1. Also disclosed are methods of inducing death of an activated T-cell and of modulating a T cell-mediated immune response in a subject.
US08828394B2
This invention relates to methods of treating IgE mediated disorders such as allergy and asthma based on activating surface-bound IgD molecules on basophils. The invention also relates to methods of making IgD, as well as methods of screening for antimicrobial agents from IgD-activated basophils.
US08828390B2
The present invention is directed to Nogo-A antagonists useful for the control of blood glucose or blood insulin levels in a subject and related use and formulation thereof. In particular, the invention is directed to Nogo-A antagonists useful for the prevention, repression or treatment insulin secretion deficiency and related methods and pharmaceutical formulations. In particular, the invention relates to Nogo-A antagonists useful in the treatment of diabetes mellitus.
US08828370B2
Disclosed is a hair conditioning composition comprising: (a) a cationic surfactant; (b) a high melting point fatty compound; and (c) an aqueous carrier; wherein the cationic surfactant, the high melting point fatty compound, and the aqueous carrier form a gel matrix; wherein the composition has from about 90% to about 100% of a conversion rate of the high melting point fatty compound to the gel matrix; and wherein the composition has a yield point of about 33 Pa or more. Also disclosed is a method of manufacturing of hair conditioning composition. The compositions of the present invention, and the compositions made by the method of the present invention, provide improved conditioning benefits, especially, improved wet conditioning benefits after rinsing and improved dry conditioning, while maintaining wet conditioning benefit before rinsing.
US08828367B2
Antiperspirant compositions for personal body care are produced as a non-aerosol, stick, soft solid, cream, gel, non-sprayable suspension, non-sprayable solution, or impregnated on a substrate and include at least one antiperspirant, at least one oil as a carrier, said oil being liquid in normal conditions, 0-7 percent by weight of free water relative to the weight of the composition, and at least one selected alkyl-modified polyether.
US08828366B2
The present invention is directed to a cosmetic composition that is moisturizing, hydrating, refreshing and long wearing, and has an unique texture and feel comprising a cellulosic gelling agent, an oil-soluble polar modified polymer, and water.
US08828359B2
Embodiments of the invention relate to particles of active substances, methods for preparing the particles, formulations containing the particles, and metered dose inhalers containing such particles or formulations. In one embodiment, a composition of an aerosol formulation is provided and contains a particulate active substance of non-micronized, solid particles having a mass median aerodynamic diameter of less than 10 μm suspended in a hydrofluorocarbon fluid vehicle at a concentration within a range from about 0.2% w/v to about 5% w/v. The aerosol formulation exhibits a flocculation volume of about 85% or greater about 1 minute after mixing the particulate active substance and the hydrofluorocarbon fluid vehicle. The particulate active substance contains an alkaloid ergotamine, pharmaceutically acceptable salts thereof, analogs thereof, or derivatives thereof. In some examples, the alkaloid ergotamine contains dihydroergotamine, such as dihydroergotamine mesylate and the hydrofluorocarbon fluid vehicle contains HFA 134a, HFA 227ea, or mixtures thereof.
US08828356B2
Although it can be farnesylated, the mutant lamin A protein expressed in Hutchinson Gilford Progeria Syndrome (HGPS) cannot be defarnesylated because the characteristic mutation causes deletion of a cleavage site necessary for binding the protease ZMPSTE24 and effecting defarnesylation. The result is an aberrant farnesylated protein (called “progerin”) that alters normal lamin A function as a dominant negative, as well as assuming its own aberrant function through its association with the nuclear membrane. The retention of farnesylation, and potentially other abnormal properties of progerin and other abnormal lamin gene protein products, produces disease. Farnesyltransferase inhibitors (FTIs) (both direct effectors and indirect inhibitors) will inhibit the formation of progerin, cause a decrease in lamin A protein, and/or an increase prelamin A protein. Decreasing the amount of aberrant protein improves cellular effects caused by and progerin expression. Similarly, treatment with FTIs should improve disease status in progeria and other laminopathies. In addition, elements of atherosclerosis and aging in non-laminopathy individuals will improve after treatment with farnesyltransferase inhibitors.
US08828350B2
A system and method are provided for recovering a re-usable grade of sulphur hexafluoride (SF6) from a potentially contaminated gas source. The system includes extraction vessels connected to the potentially contaminated gas source. A first cryogenic means reduces the temperature of the extraction vessel to a temperature below the phase transition of SF6 causing a pressure differential which causes the potentially contaminated gas to enter the extraction vessels. The SF6 turns to liquid and/or solid form in the extraction vessel. Non-condensed contaminant gas is evacuated from the extraction vessels. Recovery vessels are connected to the extraction vessel. A second cryogenic means is used to reduce the temperature of the recovery vessels. Raising the temperature of the extraction vessels creates a pressure differential which causes a re-usable grade of SF6 to enter the recovery vessels.
US08828335B2
Fluid-based no-moving part logic devices are constructed from complex sequences of micro- and nanofluidic channels, on-demand bubble/droplet modulators and generators for programming the devices, and micro- and nanofluidic droplet/bubble memory elements for storage and retrieval of biological or chemical elements. The input sequence of bubbles/droplets encodes information, with the output being another sequence of bubbles/droplets or on-chip chemical synthesis. For performing a set of reactions/tasks or process control, the modulators can be used to program the device by producing a precisely timed sequence of bubbles/droplets, resulting in a cascade of logic operations within the micro- or nanofluidic channel sequence, utilizing the generated droplets/bubbles as a control. The devices are based on the principle of minimum energy interfaces formed between the two fluid phases enclosed inside precise channel geometries. Various devices, including logic gates, non-volatile bistable memory, ring oscillators, bubble synchronizers, analysis chips, and printers have been designed.
US08828333B2
A method is provided for producing a microfluidic system on a polymer surface, wherein at least one portion of the polymer surface is irradiated by laser light in a targeted fashion for the spatially-resolved modification of the wettability of the portion of the polymer surface by a liquid sample.
US08828332B2
A microfluidic capsule (1) comprises a top lid (100), a middle piece (200) and a bottom piece (300) to be assembled to enclose a microfluidic substrate (400) for analysis of cells and biochemical reactions. The middle piece (200) comprises support structures in the form of support pillars (250) and walls (240) around a central light window (220) to provide mechanical support and prevent tension-induced structural deformations. When fully assembled, light windows (120, 220, 230) in the top lid (100), middle piece (200) and bottom piece (300) allows inspection of biological and/or biochemical samples positioned in the enclosed microfluidic substrate (400).
US08828330B2
The present disclosure provides a sensor port configured to receive a plurality of analyte sensors having different sizes, shapes and/or electrode configurations. Also provided are analyte meters, analyte monitoring devices and/or systems and drug delivery devices and/or systems utilizing the disclosed sensor ports.
US08828329B2
An improved electronic diagnostic device for detecting the presence of an analyte in a fluid sample comprises a casing having a display, a test strip mounted in the casing, a processor mounted in the casing, and a first sensor mounted in the casing and operatively coupled to the processor. The processor is configured to receive a signal from the first sensor when the device is exposed to ambient light thereby causing the device to become activated. The device includes a light shield that exerts pressure across a width of the test strip to prevent fluid channeling along the length of the test strip. The processor is configured to present an early positive test result reading when a measured value exceeds a predetermined early reading threshold value at any time after a predetermined early testing time period.
US08828328B1
Apparatuses for and methods of nano-material powder preservation and dispersion in liquid, capture, and treatments are disclosed. The applications of the present disclosure ensure powder accountability of the nano-materials preventing the nano material from dispersing into the air. The method of treating a nano-material comprises receiving a nano-material and mixing/dispersing the nano-material with a fluid in a vessel until the nano-material is sealed by the fluid. The apparatus for treating a nano-material comprises a hermetically sealable vessel containing a nano-material and a fluid, wherein the fluid is configured to increase the isolation between particles of the nano-material.
US08828321B2
A reactor comprises a main body having a flow path substrate and a crystal substrate chemically bonded to the flow path substrate to form a flow path for running a sample to be measured and a reactor tank connected to the flow path. An adsorption film is disposed in the reactor tank for adsorbing a specific substance contained in the sample to be measured. A measuring device measures a physical quantity of the specific substance contained in the sample and adsorbed by the adsorption film.
US08828314B2
The invention relates to a special hot-dip plating alloy for a coating on the surface of a titanium alloy part, wherein the hot-dip plating alloy contains the following components by mass percentage: 8-24% of Si, 1.2-3.1% of Zn, 0.02-0.5% of RE, 0.5-3.2% of Mg, 0.05-1% of Fe, 0.05-0.5% of Cu, 1.0-2.0% of Mn, 0.5-2.0% of Cr, 0.02-0.5% of Zr, 1-2% of nano-oxide particle reinforcing agent and the balance of Al and inevitable impurities, and the nano-oxide particle reinforcing agent is selected from one or two of TiO2 and CeO2. The adoption of the hot-dip plating alloy produced by the invention can form the coating which has corrosion resistance and good wear resistance, and is well metallurgically bonded with a matrix on the surface of the titanium alloy.
US08828305B2
Methods for fabricating a polymeric stent with improved fracture toughness including radial expansion of a polymer tube and fabricating a stent from the expanded tube are disclosed. The polymer tube is disposed within a mold and may be heated with radiation. The heated tube radially expands within the mold.
US08828301B2
An in-mold labeling system includes a molding apparatus having a first mold half and a second mold half that opposes the first mold half, the mold halves defining at least one mold cavity contained within a cavity wall. The in-mold labeling system further comprises a polymeric label receptor fixed to at least a portion of the cavity wall of the at least one mold cavity. The polymeric label receptor has a tacky contact face facing the inside of the at least one mold cavity when the molding apparatus is in the closed position. During a molding process, the tacky contact face of the polymeric label receptor receives a mold-side face of a label. The label is held in position against the tacky contact face during the molding process by surface tension between the mold-side face of the label and the tacky contact face of the polymeric label receptor.
US08828299B2
Method of injection molding a plastics component includes providing a first mold member with a mold cavity, defined by an internal surface, and a second mold member with an external surface complementary to the mold cavity shape. Either the internal or external surface carry an elongate formation with an elongate apex. Then, the second mold member is advanced into the mold cavity such that the apex is spaced from the opposed one of the internal surface and the external surface by a predetermined distance and the internal surface of the first mold member and the external surface of the second mold member together define a mold space. Molten polyolefin material is then injected into the mold space to substantially fill it. The predetermined distance is so dimensioned that the polyolefin material does not completely fill the space between the apex and the opposed surface and the slit is thus formed.
US08828298B2
A method and system for patterning a substrate are provided. A template is formed by applying a precursor material to a patterned master substrate and curing or solidifying the precursor material. The template is detached from the master substrate using a carrier having a curved surface. The template is coated with a patterning material, and is then detached from the carrier and applied to the substrate to be patterned. The template is then dissolved without affecting the patterning material, and the patterning material may thereafter be finished to develop the pattern. In an alternate embodiment, the patterning material may be applied to the substrate and then imprinted using the template.
US08828289B2
Two-component or multi-component fixing mortar, based on a free-radical-hardening unsaturated reactive resin, for embedding anchoring means in mortar in holes or crevices, which fixing mortar includes silanes which may or may not have reactive groups capable of participating in the polymerization with a synthetic resin based on free-radical-hardening unsaturated reactive resins but do in any case have Si-bonded hydrolysable groups, and, physically separate therefrom, a hardener.
US08828288B2
Disclosed are porous, low density nanoclay composites that exhibit highly homogeneous microcellular morphology and methods for forming the nanocomposites. The nanocomposites include a three-dimensional matrix having a non-lamellar, generally isotropic cellular structure with little or no macroscopic pores. The nanocomposites also include a gel that may be a noncovalently cross-linked, thermoreversible gel. The nanocomposites may include a binder and/or fibrous reinforcement materials. The nanocomposites may be formed according to a freeze-drying process in which ice crystal growth is controlled to prevent formation of macroscopic pores in the composite materials.
US08828283B2
An optical component and a method of producing the same, which optical component is obtained by photopolymerizing a photopolymerizable composition so as to comprise a matrix and numerous columnar structure bodies oriented in one direction within the matrix, wherein the columnar structure bodies differ in refractive index from the matrix and are arrayed in a lattice in the plane perpendicular to said orientation direction to have a highly arrayed structure whose refractive index periodically changes on the order of 80 nm to 1,000 micrometer. The optical component according to the invention is imparted with a structure whose refractive index periodically changes with high regularity on the order of about 80 nm to 1,000 micrometer and, owing to this property, is usable in optical sheet, optical film and other ordinary optical applications.
US08828273B2
Disclosed is a concentrated cooling water additive that is substantially non-corrosive within a pH range of 2-12 and contains polymeric dispersant(s) and aromatic azole(s) that exhibits improved stability, possibly as a result of the interaction of the hydrophobic groups in the dispersant polymer and the aromatic azole(s). This improved stability allows for both reduced corrosivity of the formula and reduced manufacturing costs. Benefits of the disclosed formulations include improved safety for handling and shipment, more concentrated formulations available in liquid form, reduced shipping costs and storage space, reduced heat of neutralization during product manufacture, reduced costs of manufacture due to removal of need for caustic or acid addition and reduced environmental compliance costs associated with washing and waste handling step.
US08828268B2
The present invention pertains to the field of thermosetting or thermoset polymers mainly used as materials, coatings or adhesives. The invention more specifically relates to the use of specific molecules having associative groups including a nitrogen heterocycle as a hardener or co-hardener of thermosetting polymers.
US08828266B2
A CMP slurry composition includes metal oxide particles, a diisocyanate compound, and deionized water. The CMP slurry composition is capable of selectively controlling polishing speed of a wafer surface having a convex portion and a concave portion, such that primary polishing and secondary polishing can be performed rapidly while stopping polishing of the nitride layer upon the secondary polishing.
US08828264B2
A magnetic sheet containing a binder, a magnetic powder, and a fire retardant, wherein the fire retardant contains at least one of a silicon atom-containing melamine cyanurate and a carboxylic acid amide-containing melamine cyanurate.
US08828260B2
A substrate processing method for forming a space extending along a predetermined line in a silicon substrate includes a first step of converging a laser light which is an elliptically-polarized light having an ellipticity other than 1 at the substrate so as to form a plurality of modified spots within the substrate along the line and produce a modified region including the modified spots, and a second step of anisotropically etching the substrate so as to advance an etching selectively along the modified region and form the space in the substrate. In the first step, the light is converged at the substrate such that a moving direction of the light with respect to the substrate and a direction of polarization of the light form an angle of 45° or greater therebetween, and the modified spots are made align in one row along the line.
US08828247B2
Provided is a method of manufacturing a circuit which includes: (a) providing a substrate made of a conductive material; (b) etching a first surface of the substrate excluding a region in which at least one via is to be formed; (c) etching a region of the etched first surface of the substrate in which an insulated portion of a first circuit is to be formed; (d) stacking a first insulation layer in spaces formed by the etching performed in operations (b) and (c); and (e) grinding a second surface of the substrate to expose the first insulation layer outward along with the first circuit, thereby forming a circuit board.
US08828236B2
A light weight oriented net or netting assembly is provided for oil capture and containment. The netting assembly is made by biaxially stretching or orienting starting materials to form a pattern of oriented strands and integral junctions that, while being light in weight, is also strong enough to be used to capture and remove oil from contaminated water without an outer stabilizing jacket. The assembly is preferably made from oriented polypropylene netting that is folded, gathered, bunched and/or otherwise layered upon itself on the order of 16-64 times and then crimped in one or more locations to secure the netting layers in a bow tie or tubular configuration that forms net cavities and an open cell structure to capture and contain oil that has been dispersed in water. Oil in the netting assembly can then be removed, such as by pressing or other removal process, after which the netting assembly may be reused.
US08828234B2
A device is provided for chromatographic separations comprising a manifold comprising a plurality of connectors for connecting to one or more chromatographic separation columns and/or feed or extraction tubing. At least one central duct is formed between at least two connectors forming an inlet and an outlet respectively. The central duct comprises a closable duct valve; and a plurality of branch ducts branching from the central duct to a branch connector. The branch duct comprises a closable branch valve, wherein at least one branch duct is positioned between the inlet and the central duct valve and wherein at least one branch duct is positioned between the outlet and the central duct valve. The device is arranged for carrying out single-column and (continuous) multicolumn chromatographic separations. This allows the purification of biopharmaceutical products without having to develop, demonstrate and validate cleaning procedures for the valves.
US08828218B2
This invention provides methods for multi-stage hydroprocessing treatment of FCC naphthas for improving the overall production quantity of naphtha boiling-range materials during naphtha production for low sulfur gasolines. Of particular benefit of the present processes is the selective treating of cat naphthas to remove gums instead of undercutting the overall naphtha pool by lowering the end cutpoints of the cat naphtha fraction. This maximizes the amount of refinery cat naphtha that can be directed to the gasoline blending pool while eliminating existing processing problems in hydrodesulfurization units. The processes disclosed herein have the additional benefit of minimizing octane losses in the increased naphtha pool volume.
US08828217B2
Diesel fuel is produced from a feedstock that is at least partially biocomponent in origin. A feedstock is treated in a reactor including one or more hydrotreating zones having a continuous gas phase. The liquid effluent from the hydrotreating zones is then hydroprocessed in a hydroprocessing zone having a continuous liquid phase, such as a hydroprocessing zone in the same reactor. The hydroprocessing zone can be operated under effective catalytic dewaxing conditions.
US08828209B2
This invention discloses a highly efficient method, system and apparatus for nucleic acid analysis, including sequencing (both automated re-sequencing and de-novo sequencing). The system is capable of sequencing DNA sizes ranging from fragments to mammalian size genomes having mouse draft quality at a much reduced cost. The system comprises a massive parallel capillary electrophoretic separation using two-dimensional monolith multi-capillary arrays (2D-MMCA). Sequence identification can be performed using fluorescent or otherwise labeled dideoxynucleotide-terminated DNA extension product generated by gel matrix-, or beads-, or substrate tethered-, or otherwise immobilized colonies of single template molecules. Cost reduction is a significant advantage over currently known methods because of: (i) using massively parallel sub-nanoliter volume reactions; and (ii) employing 2D-MMCAs that increase the throughput of the CE separation and detection by at least two orders of magnitude compared to the commercial high-throughput DNA machines.
US08828208B2
An apparatus for sensing of an interaction of a molecular entity with a membrane protein in a lipid bilayer comprises an array of sensor elements (21) arranged to output an electrical signal that is dependant on occurrences of the interaction. A detection circuit (3) comprised detection channels (30) capable of amplifying an electrical signal from a sensor element. More sensor elements (21) are provided than detection channels (30), and detection channels (30) are selectively connected to sensor elements (21) that have acceptable quality of performance in that a lipid bilayer is formed and that an acceptable number of membrane proteins are inserted, on the basis of the amplified electrical signals that are output from the detection channels. This improves the efficiency of utilization of the detection channels, due to inefficiency in the utilization of the sensor elements, resulting in a reduction in the cost of the apparatus and the ability to perform sensing using relatively small samples.
US08828197B2
A jig for connecting a part to a body for an on-line painting process may include a plastic adaptor and a metal hanger. The plastic adaptor may be configured to be connected to a part to be painted, and the metal hanger may be removably connectable to the plastic adaptor. The metal hanger may be configured to be connected to a body to be painted.
US08828191B2
A method and apparatus for pyrolytic destruction of polymer products including whole vehicle vulcanised rubber tires is disclosed. The apparatus 111 has a reaction chamber 153 into which a tire can be placed, and immersed for pyrolytic decomposition in a molten alloy of zinc with a minor proportion of aluminium. The apparatus 111 has a heated reservoir 155 in which the alloy is maintained in a molten state, and from where it can be transferred to the reaction chamber 153 to immerse the tire. Fluid hydrocarbon byproducts are drawn off for condensation and recovery, and solid zinc sulphides are also recovered. Where steel belted tires are processed, carbon and steel residues are also recovered.
US08828186B2
A method of peeling an electronic component. The method includes a step of, when the electronic component is adhered onto a first main surface of a tape member, bringing a bellowphragm into contact with a second main surface, which is the other main surface of the tape member; and a step of, after the bellowphragm is brought into contact with the second main face, deforming the bellowphragm and the tape member by supplying a fluid to the bellowphragm to thereby peel the electronic component from the tape member.
US08828184B2
A plasma processing apparatus includes a plasma processing chamber, a process monitor which monitors a condition in the plasma processing chamber, an actuator which controls a parameter constituting a plasma processing condition, N+1 correction amount calculating units which calculate a correction amount of a manipulated variable on the basis of a difference between a process monitor value monitored by the process monitor and a desired value of the process monitor and a correlation between the process monitor value and a manipulated variable, which is the parameter, the correlation having been acquired in advance, and N manipulated variable adding units that add a manipulated variable having a priority level next to an N-th manipulated variable. The N-th manipulated variable adding unit defines a correction amount calculated by the N+1-th correction amount calculating unit as the correction amount of an N+1-th manipulated variable.
US08828178B2
A sealing device which comprises a slinger fixedly fitted to the rotary side member, a core member fixedly fitted to the stationary side member, and an elastic sealing member fixed to the core member and having a seal lip which elastically and slidably contacts the slinger. The slinger comprises a fitting cylindrical portion to be fitted into the rotary side member, a brim portion extending its radial direction at one end of its outside relative to a sealed portion of the fitting cylindrical portion, and a rotary side fixing member fixed to the brim portion. Further, the slinger is made in such a manner that an adhesive layer is formed on its whole surface including a contacting side surface where the seal lip contacts by applying adhesive agent thereon, then the fixing member is integrally fixed thereto, thereafter the adhesive layer is partially removed only in the contacting side surface.
US08828166B2
The invention relates to a method for ultrasound welding of two bag foils to a spout, wherein at a first method step, a lateral edge of a bag foil abutting the spout is welded to the spout with a first oscillating structure, at a second method step, the lateral edge of the second bag foil abutting the opposite side of the spout is welded to the spout with a second oscillating structure, and at a third method step, the lateral edges of the two bag foils located next to the spout are welded to each other with a third oscillating structure.
US08828164B2
A chamber includes a sealed connection assembly sliding inside a translation plane, having two rigid parts, one of which comprises a groove. A planar seal and at least one O-ring seal are positioned in the groove, with the O-ring seal under the planar seal. An active surface of the planar seal, which projects above the groove, is compressed against a planar bearing surface of the other rigid part. The chamber can be used in a device for applying a plastic film onto a spectacle lens, in order to move the lens inside a variable-pressure space.
US08828152B2
A substrate includes an iron-nickel alloy core or a cobalt-nickel ferrous alloy core, a chromium conversion coating on at least a portion of the core, and an insulating coating on the chromium conversion coating. A method of making a substrate includes: providing an iron-nickel alloy core or a cobalt-nickel ferrous alloy core, applying a chromium conversion coating on at least a portion of the core, and applying an insulating coating on the chromium conversion coating.
US08828140B2
A nitride crystal is characterized in that, in connection with plane spacing of arbitrary specific parallel crystal lattice planes of the nitride crystal obtained from X-ray diffraction measurement performed with variation of X-ray penetration depth from a surface of the crystal while X-ray diffraction conditions of the specific parallel crystal lattice planes are satisfied, a uniform distortion at a surface layer of the crystal represented by a value of |d1−d2|/d2 obtained from the plane spacing d1 at the X-ray penetration depth of 0.3 μm and the plane spacing d2 at the X-ray penetration depth of 5 μm is equal to or lower than 2.1×10−3. The above configuration provides the nitride crystal having a crystal surface layer that is evaluated directly and reliably without breaking the crystal so that it can be used in a preferred fashion as a substrate for a semiconductor device as well as the nitride crystal substrate, an epilayer-containing nitride crystal substrate, a semiconductor device and a method of manufacturing the same.
US08828139B2
Methods of manufacturing a sapphire seed for growing a crystal having reduced dislocation density. The present invention provides a method of manufacturing a sapphire seed formed by a sapphire single crystal and used for growing another sapphire single crystal on a (0001) face as a crystal growing surface, the method comprising: preparing a sapphire seed whose side face forms a crystal face within a {1-100} face±10 °, and whose shape is processed so as to include a hexagonal prism or a triangle prism; and applying a predetermined thermal treatment to said sapphire seed.
US08828134B2
A method for protecting an entity from the effects of an explosion or from the effects of contact with a projectile by covering at least a part of the entity in a barrier which includes a cross-linked water gel.
US08828128B1
A system and method for controlling the humidity of an indoor space is disclosed. The system features a desiccant wheel which rotates sequentially through a plurality of distinct process air streams in order to optimize desiccant moisture adsorption at the process side of the desiccant wheel. This moisture is then deposited on the regeneration side of the wheel upstream of a cooling coil, increasing the dew point of the air entering the coil. The latent capacity and operational temperature of the coiling coil will be increased as a result, thus enhancing the dehumidification performance of the cooling coil and the overall efficiency of the system.
US08828123B2
An air cleaner includes a housing and an air filter element. An endcap of the air filter element provides a removable cover for the housing. The endcap includes removal, insertion, orientation, and retention structure and methods for same. A clamping arrangement is provided with minimal space requirements.
US08828119B2
A membrane cartridge is manufactured by repeatedly folding and joining two strips of membrane to form a cross-pleated cartridge with a stack of openings or fluid passageways configured in an alternating cross-flow arrangement. The cartridge can be modified for other flow configurations including co-flow and counter-flow arrangements. Methods for manufacturing such cross-pleated membrane cartridges, as well as apparatus used in the manufacturing process are described. Cross-pleated membrane cartridges comprising water-permeable membranes can be used in a variety of applications, including in heat and water vapor exchangers. In particular they can be incorporated into energy recovery ventilators (ERVs) for exchanging heat and water vapor between air streams being directed into and out of buildings.
US08828118B2
A pressure swing adsorption (PSA) system using two or more valves for controlling the flow of gases entering or exiting a bed of adsorbents is disclosed, where the two or more valves are opened sequentially (i.e., in at least two actions separated by a delay in time). The sequential opening of the valves may increase the degree to which adsorbed species are purged from the bed, and also facilitates more rapid execution of certain time steps of the PSA cycle, thus increasing adsorbent productivity The sequential opening of the valves may also allow for verification of valve operation by measuring either the absolute value, the slope (derivative) or the rate of change of derivative of the pressure, either in the adsorbent bed, in the downstream manifold, or in a volume of gas held in a buffer vessel.
US08828115B2
An air filter element is provided with an anti-crown support grid on a clean side of the filter media. The support grid includes one or more elongated mounting members provided along periphery portions of the grid and at least one support rib spanning between and secured at opposing ends to the mounting members. The mounting members are embedded within a peripheral seal frame. The support grid may include at least one alignment feature sized, configured and positioned to be receivable into a complimentary feature of a housing so as to positionally lock the filter element and the housing.
US08828112B2
A gas-particulate filter canister includes a filter canister body and first and second canister end caps secured to opposing ends of the filter canister body. First and second filter cartridges are supported within the filter canister body for filtering a gas in series. The filter cartridges can be standalone units which are built independently and are installed into the filter canister body. The filter cartridges can be concentrically arranged and can include a particulate filter cartridge and a gas filter cartridge.
US08828103B2
Process for the preparation of electrodes from a porous material making it possible to obtain electrodes that are useful in electrochemical systems and that have at least one of the following properties: a high capacity in mAh/gram, a high capacity in mAh/liter, a good capacity for cycling, a low rate of self discharge, and a good environmental tolerance.
US08828101B2
An agent that is capable of improving dye fastness is provided. The agent includes a compound that includes at least one functional group capable of forming at least one interaction or at least one bond with a fiber or a dye molecule. Also, a method for using the agents to improve dye fastness and a dyed article including the agent are provided.
US08828097B2
A method for forming an industrial textile product by spiral winding an array of machine direction (MD) yarns to form a system having a defined width, and then connecting the MD yarns in the cross machine (CD) direction with resin. This method is a replacement for conventional weaving or knitting of substrates which can be used as forming, press or dryer fabrics in papermaking, and other industrial applications. Devices for forming the product are also described.
US08828086B2
An orthopaedic knee prosthesis includes a femoral component having a condyle surface. The condyle surface is defined by one or more radii of curvatures, which are controlled to reduce or delay the onset of anterior translation of the femoral component relative to a tibial bearing.
US08828080B2
A method and system for repairing a defect area in a surface of a joint include providing a mold having a first surface and a second surface, positioning the mold within the joint such that at least part of the mold first surface overlies the defect area, and depositing a repair material under the mold first surface within the defect area to create a repaired site within the joint.
US08828078B2
A method for endovascularly replacing a patient's heart valve including the following steps: endovascularly delivering an anchor and a replacement valve supported within the anchor to a vicinity of the heart valve in a collapsed delivery configuration, the anchor having grasping elements adapted to grasp tissue in a vicinity of the heart valve; expanding the anchor, thereby rotating the grasping elements; and grasping the tissue with the rotating grasping elements.
US08828077B2
The present invention provides a method of fabricating a drug delivery stent. In one embodiment, the method involves forming a stent pattern in a flat sheet, where the stent pattern includes reservoirs, generating a flat map of the reservoirs, filling the reservoirs with a composition based on the flat map, and then forming the filled stent pattern into a tubular shape and joining the sides. In another embodiment, the method involves forming a stent pattern in a flat sheet, generating a flat map of discrete portions of the stent pattern that are desirable locations for coating, coating the discrete portions with a composition based on the flat map, and then forming the coated stent pattern into a tubular shape and joining the sides. The invention provides advantages over current methods and drug-delivery stents in that it is faster, more accurate and more cost-efficient manufacturing process for fabricating drug delivery stents, that improves quality and consistency of drug delivery within and across batches of stents, and that permits automated a process of quality control. This method also allows for differential coating on the two surfaces of the stent struts, whereby the two sides are coated with different drugs and/or polymer combinations, or only one side of the strut is coated.
US08828065B2
A bone screw and a method for manufacturing the same includes a screw thread configuration having one or more grooves cut into a leading face of the thread, a trailing face of the thread, and/or the shaft between the threads. Other implementations include the incorporation of facets into the one or more grooves. The implementation of the one or more grooves increases the surface are of the orthopedic screw and functions to increase in anchoring the bone screw within the bone once inserted therein, and thereby reduce the possibility for the screw backing out after insertion.
US08828054B2
A method for securing a first object to a second object, the method comprising providing a suture and a plurality of cleats slidably mounted on the suture; passing one end of the suture and a first cleat through the first object and the second object; tensioning the suture so as to secure the suture to the first cleat; passing a subsequent portion of the suture and a second cleat through the first object and the second object; and tensioning the suture so as to secure the suture to the second cleat.
US08828052B2
An anchor for securing suture to tissue, the anchor comprising: an elongated body having a distal end and a proximal end, the distal end having a distal slot extending proximally into the elongated body, and the proximal end having a proximal slot extending distally into the body; the distal slot comprising a wide section and a narrow section, wherein the wide section has a width such that the suture is slidably accommodated therein and the narrow section has a width such that the suture is bound therein, and further wherein the wide section is disposed distally of the narrow section.
US08828043B2
An implantable liner device for preventing formation of blood clots in a left atrium of a patient's heart. The liner device includes a liner body configured, in some embodiments, to cover a portion of an interior surface of the left atrium, the liner body forming a first opening sized for placement about pulmonary vein ostiums of the left atrium and a second opening for fluid alignment with a mitral valve of the left atrium. The liner body can self-expandable from a collapsed state appropriate for percutaneous delivery to the atrium to an expanded state, with the expanded state having a shape appropriate for covering the portion of the interior surface of the left atrium. The liner body can have a cap-like shape, and can be formed of mesh, fabric, braided material, and biological material such as tissue.
US08828039B2
The invention relates to a pricking device (1) for taking a blood sample, comprising a movable holding device (5) for pricking means (4), means (12) for driving the movable holding device and a release device (19) for releasing the pricking movement (13) of the pricking means. When the release device has been manually actuated, the movable holding device can be axially moved by a spring force of a drive spring (9) of the drive means (12), and a tensing device (22) for tensing the drive spring. Said tensing device comprises a tensing mechanism (23) comprising means (24) for axially stopping the movable holding device during the tensing of the drive spring and means (25) for working during the tensing of the drive spring enabling said pricking device to be comfortable to use even when being used several times.
US08828025B2
Methods and devices for providing a minimally-invasive placement of a mechanical structure for reducing the volume of a hollow body organ. Anchors may be secured within the hollow body organ and then cinched together using a tensioning member to form a stricture within the hollow body organ. In another embodiment a tensioning member may be threaded along the hollow body organ and then cinched to reduce the volume. The strictures may be placed anywhere within the hollow body organ, and more than one stricture may be formed within the hollow body organ.
US08828021B2
A robotic catheter system is provided. The catheter system includes a housing, and the housing has a sidewall and a longitudinal axis. The catheter system includes a recess formed in the sidewall of the housing and a drive mechanism supported by the housing. The drive mechanism is configured to impart movement to a catheter device. The catheter system includes a first channel configured to receive a catheter device, and the first channel has a opening located within the recess.
US08828020B2
A femoral sizing instrument for use in a knee joint replacement procedure has a housing which includes formations (4) by which it can be located relative to the femoral posterior condyles. A cortex arm (14) has a tip (16) for engaging the anterior cortex of the femur and a sulcus arm (20) has a tip (24) for engaging the sulcus. Each of the cortex and sulcus arms can be adjusted relative to the housing to adjust the distance between its tip and the posterior condyles measured generally parallel to the anterior posterior axis. The instrument includes at least one scale (13,23,27,25) for indicating the positions of the tips of the cortex and sulcus arms relative to the posterior condyles.
US08828014B2
An axial height adjustable, revision cutting in the shape of a final distal femur implant component. The revision guide includes a rod adapted for intimate contact within an intramedullary canal of a femur, and includes a threaded passageway. The revision cutting guide is adapted for removable attachment to a distal portion of the femur. A vernier-bolt is rotatably positioned through the shaped body of the revision cutting guide so as to be adjustably received within the threaded passageway thereby providing for movement of the shaped body of the revision cutting guide relative to the distal portion of the femur.
US08828012B2
An apparatus and method are provided for aligning an extramedullary femoral cut guide by referencing the anterior cortex of a femur. An anterior cortex referencing extramedullary femoral cut guide is provided to guide an osteotomy device to prepare the femur to receive a prosthesis. An alignment gauge is included in the cut guide to determine proper and improper alignment of the cut guide with respect to the anterior cortex of the femur.
US08828003B2
A method of milling a calcar region of the femur. The method includes using a miller assembly including a cutter and a frame. The frame has a longitudinal axis and a cutter mount for mounting the cutter at a first angle with respect to the longitudinal axis of the frame. The cutter mount extends at the first angle from the longitudinal axis of the frame and receives a portion of the cutter and maintain the received cutter oriented at the first angle during rotation. The frame includes a handle that forms a portion of a drive joint for coupling the frame to a drill. The handle is coupled to the drill and the miller assembly is inserted into the femur such that the cutter is located in the calcar region. The drill is then operated, causing the cutter to rotate and mill bone in the calcar region.
US08828001B2
A minimally invasive and particularly small apparatus for drilling into bone and for providing for delivery of medical treatment is provided. The directional drilling apparatus includes a miniature shaft, a bit, first shaft-mounted thrust ring, second shaft-mounted thrust ring, a tubing jacket surrounding the shaft and intermediate the first and second shaft-mounted thrust rings, and a guide tube encapsulating the tubing jacket. As a result, a hole, targeted towards a cancerous lesion within the bone, is possible. After removal of the shaft and the tubing jacket, treatment may be introduced through the particularly small passage created by the directional drilling apparatus or through the passage via a capillary inserted through at least a portion of the guide tube and the passage, which guide tube may include a hypodermic needle.
US08827999B2
A polymeric external fixator element, such as a rod or a pin or a clamp, has at least one contacting surface. At least one of the contacting surfaces of the element responsible to establish connection between the element and a different external fixator element is provided with a rough ablated structure. The clamping can be improved if one of the polymeric elements comprise fibers having fiber parts protruding above the surface.
US08827998B2
A fixation clamp for use in an external fixation system for holding bone fragments adjacent to each other with the help of fixation elements, has of at least one clamping assembly having at least one reception provided by means of grooves to accommodate a fixation element along the longitudinal axis of the reception. At least one locking element extends through the clamping assemblies for blocking the position of the clamping assemblies in a defined angular position. The clamping assembly comprises a first jaw and a second jaw which are in contact with each other via respective contact surfaces. The clamping assembly comprises at least two orientation devices that extend from and/or into said contact surfaces which at least two orientation devices serve to orient the first jaw with respect to the second jaw.
US08827997B2
A fixation clamp for use in an external fixation system for holding bone fragments adjacent to each other with the help of fixation elements has at least one clamping assembly having a pair of jaws with at least two different size grooves to accommodate a bone fixation element such as a pin or rod. An alternate clamping assembly has at least three grooves wherein at least two of the grooves have a different size adapted to accommodate a correspondingly sized bone fixation element such as a bone pin. The longitudinal axes of the grooves define a polygon. The jaw pairs can be rotated about a central longitudinal axis to present different size reception cavities towards the pins or rocks depending on their diameter.
US08827981B2
Methods and devices for augmenting bone, such as in performing vertebroplasty are disclosed. A bone cement injection needle is provided, having a laterally deflectable distal end. The distal end may be provided with a cavity creation element, such as an inflatable balloon. Systems are also disclosed, including the steerable injection needle, introducer and stylet. The system may additionally include a cement delivery gun, one-time use disposable cement cartridges and a cement mixing chamber. Methods are also disclosed.
US08827975B2
The present invention relates to an intravaginal tampon for feminine hygiene includes a generally cylindrical absorbent pledget and a withdrawal element operatively connected to the generally cylindrical pledget proximate to the withdrawal end thereof. The absorbent pledget includes a mass of fibers compressed into a self sustaining shape and a sheet-like fluid-permeable cover substantially enclosing the mass of fibers. The absorbent pledget has formed thereon or therein a plurality of detached groove forms. At least two of said detached groove forms each has a length, measured along the groove, that is at least 150% of the length of the pledget; each has a major axis having a generally longitudinal orientation; and each has a turn proximate to at least one of the insertion end and the withdrawal end.
US08827973B2
A reduced-pressure medical treatment system for treating a tissue site on a patient includes a medical drape that has an holographically-formed polymer dispersed liquid crystal (H-PDLC) device that changes visual appearance when experiencing strain. The change in visual appearance of the H-PDLC device allows identification of the existence of strain and may allow a quantitative assessment of the range of stress involved. In other aspects, a dressing conduit connector, canister, and reduced-pressure interface use a holographically-formed polymer dispersed liquid crystal (H-PDLC) device to help determine the existence and perhaps the amount of stress experienced. Other systems, methods, and devices are presented.
US08827970B2
The end of the elongated tubular element of the appliance that is designed to be inserted into a body cavity is formed entirely of soft, compliant material. That end carries an inflatable balloon made of non-expandable material, formed in the fully inflated shape, to prevent overexpansion. The balloon is inflated to a predetermined low pressure level to prevent pressure necrosis in the adjacent tissue. A method and apparatus for introducing the soft end of the appliance into the body cavity are also provided. The introducer apparatus includes rigid core surrounded by a soft, compliant sleeve. The sleeve extends beyond the rigid core to form an invertable section. The soft end of the appliance is situated adjacent the apparatus, the balloon is wrapped around the apparatus, and the sleeve section is inverted over the appliance, compressing the balloon and forming a soft, rounded insertion tip. The unit is then introduced into the body cavity. After the appliance is separated from the apparatus, the apparatus is withdrawn.
US08827961B2
A safety needle for automatically covering a tip of a needle following removal of the needle from a patient is provided. The safety needle includes an injection device and a packing sleeve. The injection device has an initial position and an intermediate position. The packing sleeve has a generally hollow body surrounding at least a portion of the injection device in the initial position and the intermediate position. The hollow body includes at least one track having an activation leg and a releasing leg. The at least one track is configured to slidingly engage with at least one member of the injection device to move the injection device to the intermediate position. The packing sleeve is removable from the injection device only when the injection device is in the intermediate position.
US08827960B2
A catheter anchoring system, apparatus and method for securing a catheter to a patient's skin, having two flexible side members and a cross-member therebetween to which a retaining assembly is mounted. The retaining assembly may hold a catheter hub at an angle for patient comfort. Gripping tabs secure to each retaining assembly side are gripped while advancing a cannula guide needle into the patient's vein and while attaching the catheter hub to a medical accessory, such as intravenous (I.V.) tubing, for increased patient comfort, reduction of the risk in contamination and patient infection, and to more easily and quickly start an I.V.
US08827944B2
A novel ventricular catheter designed to reduce CSF shunt obstruction is disclosed comprising a tip using a membrane without any opening and capable of filtering the CSF. When the CSF flows through the membrane, neither tissue (choroid plexus, blood cells, tumor cells, suctioned ependymal tissue) nor proteins can break through the membrane, making this ventricular catheter capable of preventing obstruction from tissue invasion but also preventing clogging from protein precipitation, coagulation or flocculation along the downstream shunt system.
US08827938B2
A massage machine includes a seat portion, a backrest portion and a rocking mechanism center where the backrest portion reclines at a back portion side of the seat portion about a reclining center. The rocking mechanism portion swings the backrest portion and the seat portion about a rocking center, and the rocking center is apart or different from the reclining center.
US08827931B2
The present invention provides a hospital bed including a force sensor or scale apparatus configured to detect the weight of a patient.
US08827929B2
An apparatus for measuring distensibility of a vessel, lumen or sphincter includes a balloon catheter having a balloon located adjacent a distal end of a catheter for inserting in, for example, the sphincter, the distensibility of which is to be determined. The balloon is inflated to respective first and second pressures to distend the sphincter to respective first and second transverse cross-sectional areas which are measured. The first and second pressures are selected so that the relationship between the pressure and the cross-sectional area of the sphincter is linear. The distensibility of the sphincter is determined as a distensibility index, which is the value of c from the equation of a line y=mx+c containing the values of the first and second pressures and areas, where x represents pressure and y represents area.
US08827926B2
A guide wire includes an elongated wire body and a radiopaque part capable of forming an X-ray image and located at the distal end portion of the wire body. The radiopaque part has a radiopaque member and a resin coating layer. The radiopaque member is composed of a metallic material capable of forming an X-ray image and arranged outside the wire body and in the lengthwise direction of the wire body. The resin coating layer covers the radiopaque member and at least part of coating layer contains a radiopaque material capable of forming an X-ray image. The radiopaque part is divided into a first radiopaque region, a second radiopaque region, and a third radiopaque region which are sequentially arranged from the distal end in the lengthwise direction of the wire body.
US08827924B2
A diagnostic method and apparatus for detecting at least one change in a urinary parameter indicative of a body malfunction, the method comprising at least semi-continuously monitoring in real time at least one of a sodium level, an oxygen level, a potassium level, and combinations thereof in the urine of a catheterized patient; whereby at least one parameter is monitored so as to detect one or more changes in the at least one parameter to reflect at least one of a fluid state, an electrolyte balance, a kidney state, a kidney perfusion and an organ perfusion in the patient, indicative of the body malfunction in the patient, in which the monitoring is preferably performed through electrodes that are arranged perpendicularly to the flow of urine through a patient's catheter system.
US08827923B2
A sampling device adapted for transcervical sampling of biological materials from a pregnant patient comprising: an elongate insertion tube (4) having a first end (5) adapted for insertion through the external orifice (external os) of said patient's cervix and a second end (6) including a handle means (7) for manipulating said tube; a measuring means for determining the position of said first end of said tube within said cervix, wherein said first end (5) includes a sampling head (9, 14) adapted to collect biological material including cells, mucus and biological fluids, and wherein said measuring means is adapted to determine the extent of insertion and transcervical position of said first end to optimise the transcervical sampling site.
US08827920B2
The present invention relates to a telemedical stethoscope, which automatically diagnoses a disease, and records visually and auditorily, and stores the stethoscope data on a screen. The present invention enhances primary diagnosis and treatment effect for a patient by transmitting/receiving the data to/from a doctor at a medical center and by receiving a telemedicine service. In addition, the present invention transmits the data to a health management program so as to be used for personal healthcare and disease prognosis decision of a patient.
US08827918B2
A ballistocardiogram-based personal authentication method includes detecting ballistocardiogram training signals of persons to be registered, extracting training features from the detected ballistocardiogram training signals, generating training data for personal authentication based on the extracted training features, detecting ballistocardiogram authentication signals of persons to be authenticated, and comparing the ballistocardiogram authentication signals and the training data to determine whether or not to perform the personal authentication of the persons to be authenticated. Thereby, the personal authentication method can perform personal authentication according to feature of a ballistocardiogram of each individual.
US08827915B1
A system and method (1000) for an interactive game is disclosed herein. The system (1000) preferably includes monitoring device (20) monitoring the vital signs of a user, an interface (1115), a game console (1010) and an accessory (1020). The monitoring device (20) is preferably an article (25) having an optical sensor (30) and a circuitry assembly (35), and a pair of straps (26a and 26b). The monitoring device (20) preferably provides for the display of the following information about the user: pulse rate; blood oxygenation levels; calories expended by the user of a pre-set time period; target zones of activity; time; distance traveled; and/or dynamic blood pressure. The article (25) is preferably a band worn on a user's wrist, arm or ankle.
US08827910B2
A catheter includes a flexible tubing having a proximal end and a distal end. The catheter also includes an electrode assembly attached to the distal end of the flexible tubing and including a first magnet therein. The electrode assembly including an electrically conductive tip electrode and an electrically nonconductive coupler which is connected between the tip electrode and the distal end of the flexible tubing. The electrically conductive tip electrode comprises a hollow elongated tip electrode including a sidewall provided with one or more elongated gaps extending through the sidewall. The one or more elongated gaps providing flexibility in the sidewall for bending movement of the tip electrode relative to a longitudinal axis of the catheter body. The first magnet is responsive to an external magnetic field to selectively position and guide the electrode assembly within a body of a patient.
US08827907B2
A system for producing an ultrasound image comprises a scan head having a transducer capable of generating ultrasound energy at a frequency of at least 20 megahertz (MHz), and a processor for receiving ultrasound energy and for generating an ultrasound image at a frame rate of at least 15 frames per second (fps).
US08827893B2
A slotted cannula for endoscopic surgical procedures is disclosed. The slotted cannula has a tubular body having a distal end, a proximate end, an open slot extending longitudinally from the beginning of the proximate end to the proximity of the distal end, and a pair of wings integrally formed on the proximate end. The tubular body is made from a transparent material and has an inner diameter large enough to accommodate an endoscope.
US08827887B2
A needle guard is used when suturing the cuff of an attachment ring to the heart. The needle guard is disposed in the attachment ring to prevent other parts of the attachment ring from being punctured by a suturing needle. The needle guard can include one or more grooves to inhibit relative movement between the needle guard and the attachment ring during suturing. The needle guard is removed upon completion of suturing and to allow insertion into attachment ring of an inflow conduit of a heart assist device. An articulated clamp is used to compress the attachment ring into engagement with the inflow conduit. The attachment include an annular rib that grabs the inflow conduit.
US08827886B2
A method, apparatus and a system for thermally-assisted pulsed electromagnetic field stimulation for treatment of osteoarthritis are disclosed. In one embodiment, the system comprises a multi-coil applicator adapted for positioning near or around of the treated joint, a pulse generator functionally coupled to the applicator, a power supply, and a feedback loop for stabilizing the temperature of the joint. The feedback loop includes a heating element, a temperature sensor and an electronic controller for maintaining the temperature of the joint in the range of 38 to 42 degree C. At elevated temperatures the healing effect of PEMF stimulation on the cartilage is maximized and overall efficiency of the treatment is improved. To produce a high electric field, the coils of the applicator are made with a low number of turns, for example less than 5 turns, and are spatially arranged to cover the whole joint without “dead” zones.
US08827884B2
An oncology therapy method comprises implanting a radioactive seed (10, 20, 30, 40, 50) in an oncology subject (S). In some embodiments the radioactive seed comprises a radioactive material (12, 32, 33, 42) including at least one radioisotope disposed in a biodegradable host (14, 24, 25, 44) configured to biodegrade over a therapy time period when implanted in the oncology subject. In some embodiments the radioactive seed is implanted in soft tissue of an oncology subject (S), and the radioactive seed comprises a radioactive material (12, 32, 33, 42) including at least one radioisotope disposed in a host material (14, 24, 25, 44) having softness comparable with or softer than the soft tissue into which the radioactive seed is implanted.
US08827875B2
An apparatus including first, second, third, and fourth vertical members, a first top horizontal member which joins a top of the first and a top of the second vertical members, a second top horizontal member which joins a top of the third and a top of the fourth vertical members, and a third top horizontal member which joins a top of the first top horizontal member and a top of the second top horizontal member. The first, second, third, and fourth vertical members, and the first, second, and third top horizontal members form a cage structure. The apparatus may also include first and second dumbbell holder members adjustably fixed to the cage structure. The apparatus may also include devices for suspending a first and a second dumbbell from the cage structure.
US08827872B2
The subject matter discloses a bicycle device capable of functioning as an upright bicycle and a recumbent bicycle using one seat. The bicycle device according may comprise a seat, a body, a wheel operated by the user of the exercising device and a directing rod connecting the body and the seat. Such that movement of the directing rod allows positioning the seat in front position used for upright bicycle and rear position used for recumbent bicycle.
US08827870B2
An exercise guidance system and method dynamically adjusts an exercise route for meeting a fitness objective based upon a comparison of the route and actual received exercise metrics on an exercise device.
US08827868B2
A method of cooling a multi-speed dual-clutch transmission (DCT) that is paired with an internal combustion engine in a vehicle includes detecting operation of the vehicle. The method also includes sensing an increase in temperature of a subsystem of the DCT while the vehicle is operating. The method also includes selecting a remedial action in response to the sensed temperature. The method aditionally includes activating the selected remedial action such that the temperature of the subsystem is reduced.
US08827851B2
To provide a power transmission belt and a method of producing the same that allows lightweight elements to be produced at low cost and allows the durability to be sufficiently ensured, the power transmission belt includes a plurality of elements each having both side end surface portions, a rocking edge portion rockably engaged with either one of a pair of other elements neighboring the element, and a concave-convex engagement portion engageable with the pair of other elements, in which each of the elements has a plate-like portion, a first convex portion projecting from one surface of the plate-like portion, and a second convex portion projecting from the one surface of the plate-like portion in a spaced relationship with the first convex portion to constitute the rocking edge portion, and each of the elements is engaged with the pair of other elements so as to press against one another by the first convex portion and the second convex portion.
US08827847B2
A training aid (10) provides real-time biometric feedback for swung or linearly accelerated implements where the feedback is provided above a user adjustable threshold. The training aid (10) includes a two-part housing (12) and mounting means for releasably mounting the housing to an implement. A battery (16) is located in the housing (12) with a buzzer (22) connected to the battery (16) through an electrical circuit. A force activated switch (14) in the electrical circuit is activated to energize the buzzer (22) to sound in response to displacement of the training aid. The force activated switch (14) has a force threshold at which the force activated switch (14) is activated to energize the buzzer (22) to sound. The force activated switch (14) is configured so that the force threshold is user adjustable.
US08827845B1
The Frisbee disc golf practice tower includes a plurality of vertically stacked baskets that collect Frisbee discs that are thrown into a front opening of each basket, and which are used as a means of practicing Frisbee golf putting or in connection with a game. The baskets are formed from a plurality of tubular components that connect, and from which netting spans along each basket at a rear surface, side surfaces, and a bottom surface. A top basket includes a backboard that enables a bank shot to be made therein. The tubular construction of the practice tower can collapse between uses, and arise from base members that secure the practice tower upon different ground surfaces.
US08827844B2
A training apparatus for use in training football basic technique is disclosed, comprising one opening on each side of the apparatus being adapted to entrance angles for at least one rail guiding a ball in a loop from one opening to the other, and a wall adjustable in height as well as sideways is fixed between said openings, where both openings for the ball can be used as entrance/exit and vice versa.
US08827842B2
A golf equipment fitting system that uses advanced technology to not only objectively identify the optimum equipment for the golfer, but to also identify and help correct swing flaws so that the golfer can achieve optimum performance on the golf course. Thus, in one embodiment, golf fitting includes collecting data related to the golfer's swing and determining if the golfer's swing technique should be modified based at least in part on the collected swing data. When it is determined that the golfer's swing technique should be modified, then providing swing instruction to the golfer. When, however, it is determined that the golfer's swing technique is fine, then collecting data related to how the golfer's swing launches a golf ball. Finally, golf equipment, e.g., golf clubs, can be specified based on the collected swing data and launch data.
US08827840B2
A multi-piece solid golf ball composed of a solid core having an inner core layer and an outer core layer encased by a cover including at least an inner cover layer and an outer cover layer. The inner core layer has a JIS-C cross-sectional hardness of from 60 to 83 at any single point on a cross-section, and has a cross-sectional hardness difference between any two points on the cross-section of within ±5. The ball has specific relationships between the hardness of the inner core layer 1 mm inside a boundary between the inner core layer and the outer core layer, the hardness of the outer core layer 1 mm outside the boundary, and the surface hardness of the outer core layer. And, the outer cover layer has the specific Shore D hardness, which is lower than that of the inner cover layer.
US08827833B2
There is provided a golf club head capable of reliably preventing a backspin rate from varying in rainfall. A plurality of fine grooves are formed on a face surface 2. When observing a cross-sectional surface perpendicular to the face surface 2 involving a vertical line passing through the center G of gravity of the golf club head 1 with the golf club head 1 set at preset loft and lie angles, an average width of the fine grooves 4 in the cross-sectional surface is 100 μm or less and an average pitch thereof in the cross-sectional surface is 100 μm or less. Hence, the discharge of water can be accelerated by a capillary phenomenon, making it possible to reliably prevent a backspin rate of a golf ball from varying in rainfall.
US08827831B2
A hollow golf club incorporating a stress reducing feature including at least a toe located stress reducing feature or a heel located stress reducing feature at least partially located on the skirt of the golf club head. The location and size of the stress reducing feature and their relationship to one another play a significant role in selectively increasing deflection of the face.
US08827812B2
To provide a game device that is capable, in a match in which a player character group including operating characters of a plurality of game players and one or more teammate character competes with an opponent character or an opponent character group opposing the player character group, of improving diversity of combination of the characters belonging to the player character group while suppressing increase of data amount. An operating character obtaining unit (30) obtains the player data on an operating player of each game player. A teammate character obtaining unit (32) obtains the player data on a teammate player of each game player. A game execution unit (36) carries out a game in which an operating team takes part in a soccer match with an opponent team, based on the player data on the respective operating players and that on the respective teammate players.
US08827809B2
A game apparatus acquires operation data from an input device at least including a gyroscope, wherein the operation data at least contains angular rate data from the gyroscope. The game apparatus sets a predetermined reference position in a predetermined plane when a player inputs a predetermined instruction, and then calculates a coordinate point based on the angular rate data, wherein the coordinate point represents a position in the predetermined plane relative to the reference position. A game process is performed based on the coordinate point.
US08827807B2
Systems and methods include determining a hardware configuration in accordance with the detection of the presence or absence of hardware modules on a wagering game machine. Various services are selected base on the hardware configuration, where the service selected provides an interface to a wagering game. The services provide an abstraction of various functions provided by various hardware platforms upon which the wagering game may execute, and take into account differences in the platforms.