Invention Grant
US08828699B2 Eukaryotic amadoriase, gene and recombinant DNA for the eukaryotic amadoriase, and process for production of the eukaryotic amadoriase
有权
真核阿马道里酶，真核阿马道里酶的基因和重组DNA，以及生产真核阿马道里酶的方法
- Patent Title: Eukaryotic amadoriase, gene and recombinant DNA for the eukaryotic amadoriase, and process for production of the eukaryotic amadoriase
- Patent Title (中): 真核阿马道里酶，真核阿马道里酶的基因和重组DNA，以及生产真核阿马道里酶的方法
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Application No.: US12985858Application Date: 2011-02-14
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Publication No.: US08828699B2Publication Date: 2014-09-09
- Inventor: Kozo Hirokawa , Atsushi Ichiyanagi
- Applicant: Kozo Hirokawa , Atsushi Ichiyanagi
- Applicant Address: JP Noda-Shi, Chiba
- Assignee: Kikkoman Corporation
- Current Assignee: Kikkoman Corporation
- Current Assignee Address: JP Noda-Shi, Chiba
- Agency: Andrews Kurth LLP
- Agent Ping Wang
- Priority: JP2006-120363 20060425
- Main IPC: C12N9/06
- IPC: C12N9/06 ; C12N9/02 ; C12N1/20 ; C12N15/00 ; C12P21/06 ; C12P19/34 ; C07H21/04
Abstract:
Disclosed are: a eukaryotic amadoriase which is prepared by introducing a mutation into DNA encoding a eukaryotic amadoriase derived from a microorganism belonging to the genus Coniochaeta or Eupenicillium so as to introduce a substitution into a specific amino acid residue in the eukaryotic amadoriase, thereby overcoming the defect associated with thermal stability; a gene or recombinant DNA for the eukaryotic amadoriase; and a process for production of a eukaryotic amadoriase having excellent thermal stability.
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