Invention Grant
US08828397B2 Anti-PSGL-1 antibodies and methods of inducing cell death of an activated T cell
有权
抗PSGL-1抗体和诱导活化的T细胞的细胞死亡的方法
- Patent Title: Anti-PSGL-1 antibodies and methods of inducing cell death of an activated T cell
- Patent Title (中): 抗PSGL-1抗体和诱导活化的T细胞的细胞死亡的方法
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Application No.: US13616801Application Date: 2012-09-14
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Publication No.: US08828397B2Publication Date: 2014-09-09
- Inventor: Rong-Hwa Lin , Chung Nan Chang , Pei-Jiun Chen , Chiu-Chen Huang
- Applicant: Rong-Hwa Lin , Chung Nan Chang , Pei-Jiun Chen , Chiu-Chen Huang
- Applicant Address: NL Alkmaar
- Assignee: AbGenomics Cooperatief U.A.
- Current Assignee: AbGenomics Cooperatief U.A.
- Current Assignee Address: NL Alkmaar
- Agency: Wolf, Greenfield & Sacks, P.C.
- Main IPC: A61K39/395
- IPC: A61K39/395 ; C07K16/28 ; C07K16/46
Abstract:
Immunoglobulin chains or antibodies having light or heavy chain complementarity determining regions of antibodies that bind to P-Selectin Glycoprotein Ligand-1. Also disclosed are methods of inducing death of an activated T-cell and of modulating a T cell-mediated immune response in a subject.
Public/Granted literature
- US20130101587A1 ANTI-PSGL-1 ANTIBODIES Public/Granted day:2013-04-25
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