Invention Grant
- Patent Title: Dual modulators of 5HT2A and D3 receptors
- Patent Title (中): 5HT2A和D3受体的双重调节剂
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Application No.: US13772390Application Date: 2013-02-21
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Publication No.: US08829029B2Publication Date: 2014-09-09
- Inventor: Luca Gobbi , Georg Jaeschke , Olivier Roche , Rosa Maria Rodriguez Sarmiento , Lucinda Steward
- Applicant: Hoffmann-La Roche Inc.
- Applicant Address: US NJ Nutley
- Assignee: Hoffmann-La Roche Inc.
- Current Assignee: Hoffmann-La Roche Inc.
- Current Assignee Address: US NJ Nutley
- Main IPC: A61K31/445
- IPC: A61K31/445 ; C07D413/04

Abstract:
The present invention relates to compounds of the formula (I) wherein R1, R2, X and n are as defined in the specification as dual modulators of the serotonin 5-HT2a and dopamine D3 receptors, their manufacture, pharmaceutical compositions containing them and their use for the treatment of psychotic disorders, as well as other diseases such as depression and anxiety, drug dependence, dementias and memory impairment.
Public/Granted literature
- US20130165432A1 Dual Modulators of 5HT2A and D3 Receptors Public/Granted day:2013-06-27
Information query
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