Six-axis four-subdividing interferometer comprising a six-axis light splitting system and an interference module which are sequentially arranged along the incident direction of polarization orthogonal double-frequency laser, wherein the six-axis light splitting system comprises five 45-degree plane beam splitters and four 45-degree full-reflecting mirrors.
An apparatus for testing the reflectivity of a material under test includes a rotating carriage, a light source, and a light detector. At least two sample units are mountable to the rotating carriage. Each sample unit includes a planar surface disposed under a portion of a hemispherical surface. The light source is mounted on a pivoting boom and generates light. The light detector is mounted to measure optical power of the light emitted from the light source and reflected from a selected one of the at least two sample units. The pivoting boom and the rotating carriage rotate through different angular positions to obtain reflectance signatures as a function of incident angles for the at least two sample units.
A method of analyzing chemical species in a solution, the method comprising: providing an electrochemical deposition apparatus comprising a first electrode (2) formed of an electrically conductive diamond material and a second electrode (4); locating the first electrode in contact with a solution (8) to be analyzed and the second electrode in electrical contact with the solution to be analyzed; applying a potential difference between the first and second electrodes (2, 4) such that current flows between the first and second electrodes through the solution to be analyzed and chemical species are electro-deposited from the solution onto the first electrode; applying a spectroscopic analysis technique to the electro-deposited chemical species (M1, M2, M3) on the first electrode to generate spectroscopic data about the electro-deposited chemical species on the first electrode; and using the spectroscopic data to determine the type of chemical species electro-deposited on the first electrode. The spectroscopic analysis technique, which can be based on X-rays, fluorescent X-rays or gamma rays, is used in combination with stripping voltammetric measurement performed on the first electrode. The spectroscopic data can also be used in-situ calibration data for calibrating the reference potential used voltammetric measurements.
An inspection apparatus comprising, a Rochon prism configured to branch the light transmitted through a half-wave plate, a first sensor and a second sensor for acquiring an optical image of a pattern of the sample, the branched light being incident to the first sensor and the second sensor, a light quantity acquisition unit configured to acquire a light quantity ratio (1:A) of the second sensor to the first sensor using the optical image, and to obtain an angle θ of the half-wave plate such that the light quantity ratio becomes A:1, an angle controller configured to receive information on the angle θ from the light quantity acquisition unit to control an angle of the half-wave plate, a light source controller configured to control a light quantity of the light source such that each of the light quantity values becomes a target value.
An optical characteristic measurement apparatus acquires a measurement value pertaining to an image characteristic of an optical system to be tested on a plurality of evaluation planes, and measures an optical characteristic, comprising a measurement value correction unit correcting a measurement value pertaining to a width or a light intensity of one of a line spread distribution and a point spread distribution of a beam, on the evaluation planes, wherein: in case where the measurement value pertains to the width, the image plane is regarded as an evaluation reference plane, and the measurement value correction unit outputs a corrected value; in case where the measurement value pertains to the light intensity, the image plane is regarded as an evaluation reference plane, and the measurement value correction unit also outputs a corrected value; and the optical characteristic of the optical system to be tested is measured based on the corrected value.
The disclosure provides a method and a system for detecting a fiber fault in a Passive Optical Network (PON). The system comprises an optical path detection device, a Wavelength Division Multiplexing (WDM) coupler, a wavelength selection coupler, a branch fiber selector and a wavelength selection router. The detection system is attached to an original PON system, without influencing the operation of the original system while performing the detection. With the disclosure, the problem of being unable to determine whether there is a fault in a branch fiber due to the loss of an optical path detection reflection signal is solved, the branch fiber with a fault can be quickly located and fixed, thus the operational and maintenance costs of an operator are reduced.
The invention relates to an electro-optical distance measuring device comprising a transmitting unit comprising a light source for emitting intensity-modulated optical radiation, a receiving unit for receiving a portion of the optical radiation, said portion being reflected from a target object, by means of a photosensitive electrical component and for converting it into an electrical reception signal. Furthermore comprising a conditioning unit for conditioning the reception signal comprising at least one amplifier stage, an analog-to-digital converter fox digitizing the conditioned reception signal, and an electronic evaluation unit, which is designed in such a way that a distance from the distance measuring device to the target object, can be determined on the basis of a signal propagation time with the aid of the digitized reception signal. According to the invention, in this case the amplifier stage is designed in such a way that it has a non-linear input-output characteristic.
An immersion lithographic apparatus is disclosed that includes a fluid supply system configured to supply a fluid, the fluid supply system having a chamber with a plurality of inlet holes in a first side wall and a plurality of outlet holes in a second side wall, the first side wall facing the second side wall, wherein the inlet holes direct fluid entering the chamber in a direction towards areas of the second side wall between the plurality of outlet holes.
Disclosed is a display device. The display device includes an upper substrate; a lower substrate having gate and data lines, with exposing a part of the lower surface of the upper substrate; a sealant for adhering the upper substrate to the lower substrate; a panel driver connected to the part of a lower surface of the upper substrate; a pad formed on the lower substrate, for applying a signal to the gate and data lines; and a connection part formed on the upper substrate, for connecting the pad and the panel driver. Accordingly, the thickness of the display device decreases, and a step height is not formed at a front surface of the display device, whereby the present invention can obtain an aesthetic design effect in that the front surface of the display device is shown as one structure.
A Liquid Crystal Display (LCD) module for preventing a hot spot that deteriorates an external appearance quality using existing components is provided. The LCD module includes an optical sheet disposed at an upper surface of a light guide plate, a Light Emitting Diode Flexible Printed Circuit Board (LED FPCB) on which an LED for emitting light to the light guide plate is mounted, and a double-sided tape having a portion protruding toward the optical sheet further than the LED FPCB and adhered to a mounting surface of the LED FPCB. Therefore, occurrence of a hot spot can be reduced without increasing components. Further, because a thickness increase of a local portion is unnecessary, a second failure such as panel lifting is not caused.
A display apparatus includes a display panel including a protective electrode and a ground pad that is applied with a ground voltage, a conductive member electrically connecting the ground pad and the protective electrode, a backlight unit providing light to the display panel, a bottom chassis accommodating the backlight unit, and at least one fixing member fixing a side portion of the display panel and a side portion of the bottom chassis to each other. The fixing member makes contact with the conductive member and the bottom chassis to electrically connect the conductive member and the bottom chassis.
The present invention provides a flat panel display device, which includes a backlight system and a display panel, the backlight system including a light source, a light homogenization mechanism, and a back frame; the back frame carries the light source and the light homogenization mechanism, the light homogenization mechanism guiding light from the light source to a light incidence surface of the display panel; the back frame includes primary assembling pieces and secondary assembling pieces; the primary assembling pieces are of a number of at least two, the at least two primary assembling pieces being joined to form a main frame structure of the back frame; the secondary assembling pieces are arranged inside the back frame and joined to the back frame; some of the primary assembling pieces and the secondary assembling pieces are of first density and first strength and others are of second density and second strength; the first density is greater than the second density and the first strength is greater than the second strength. The present invention also provides a stereoscopic display device and a plasma display device. The back frame mold of the present invention is of a simple structure and can reduce the expenditure of the back frame mold, and can also save the material used for back frame so as to lower down the cost of flat panel display device.
The embodiment of the invention discloses a liquid crystal display and a method of manufacturing the same. The liquid crystal display of the embodiment of the invention comprises an array substrate, a color filter substrate and a liquid crystal layer formed between the array substrate and the color filter substrate. The array substrate comprises a first substrate; a black matrix formed on the first substrate; and a thin film transistor (TFT) device formed on the black matrix. The TFT device is a top gate TFT device having a gate electrode formed on a side of the TFT device facing away the black matrix and an active layer made of a-Si. The color filter substrate comprises a second substrate; and a color filter layer formed on the second substrate. The color filter substrate does not include a black matrix.
Disclosed is LCD device and a method of manufacturing the same, which increases a margin between the channel width and length (W/L) of a thin film transistor having a multi-gate structure, wherein the device comprises a substrate where a plurality of pixel regions are defined by a data line and a gate line; an active layer formed at each of a plurality of pixel regions of the substrate; a gate electrode comprising a plurality of multi-patterns overlapping with the active layer with an insulation layer therebetween; and a data electrode electrically connected to the active layer, wherein the multi-patterns are formed in straight by compensating pattern distortion of an edge portion of a gate pattern, and formed with the gate pattern which is designed to comprise a plurality of compensation patterns.
A gradient index liquid crystal optical apparatus according to an embodiment includes: a first substrate having a first face; a second substrate having a second face opposed to the first face of the first substrate; a liquid crystal layer sandwiched between the first substrate and the second substrate; a plurality of first electrodes provided on the first face of the first substrate, and arranged along a first direction; a plurality of second electrodes provided on the first face of the first substrate to correspond to the first electrodes, the plurality of second electrodes being arranged along the first direction; a plurality of third electrodes provided on the first face of the first substrate and arranged along the first direction; and a fourth electrode provided on the second face of the second substrate.
A method for displaying a main image includes: populating a plurality of image entries in a video frame based on the main image; selecting an image entry specifying a first color; determining a compensation entry of a plurality of compensation entries in the video frame associated with the image entry; selecting a second color based on the first color; setting the compensation entry to the second color; and outputting the video frame with the image entry and the compensation entry for display on a display device.
A combination apparatus and an operating method thereof are provided. The combination apparatus includes a first device, a second device and a connecting mechanism. The first device includes a first display unit and a first image capturing unit, wherein a picture is captured by the first image capture unit and converted into an image signal for the first display unit to display. The second device includes a second display unit with resolution different from that of the first display unit and is capable of wirelessly controlling the first device. The connecting mechanism is configured to detachably fasten the first device and the second device. The operating method of the combination apparatus includes utilizing the first device and/or the second device to capture a picture; and utilizing the first display unit and/or the second display unit to display the picture.
A method of reducing light damage in a shutterless imaging device includes receiving a signal from a hardware device. The signal from the hardware devices is analyzed. In response to the analysis of the signal from the hardware device, a lens of the shutterless imaging device is adjusted. Adjusting the lens spreads out energy of far-field image light incident on an image sensor of the shutterless imaging device.
Described is a method and apparatus for unattended image capture that can identify subjects or faces within an image captured with an image sensor. The methods and apparatus may then score the image based, at least in part, on scores of detected subjects or faces in the image, scores of facial expressions, a focus score, exposure score, stability score, or audio score. If the score of the image is above a threshold, a snapshot image may be stored to a data store on the imaging device. If the score of the image is below a threshold, one or more audible prompts may be generated indicating that subjects should change positions, smile or remain more still during the image capture process.
A single-plate color imaging element where the color filter array includes a basic array pattern with first filters corresponding to a first color and second filters corresponding to a second color with contribution ratios for obtaining luminance signals lower than the first color, the basic array pattern is repeatedly arranged in a diagonal grid shape, one or more first filters are arranged in horizontal, vertical, upper right, and lower right directions of the color filter array, one or more second filters corresponding to each color of the second color are arranged in the upper right and lower right directions of the color filter array in the basic array pattern, and a proportion of the number of pixels of the first color corresponding to the first filters is greater than a proportion of the number of pixels of each color of the second color corresponding to the second filters.
Provided is an imaging device including an image sensor for outputting a high-sensitivity pixel signal from a long-time exposure pixel and a low-sensitivity pixel signal from a short-time exposure pixel; and a blooming correction processing unit for receiving the output pixel signal from the image sensor and executing blooming correction for the pixel signal. The blooming correction processing unit executes pixel value correction of the input pixel from the image sensor according to a difference between or a ratio of an input pixel value from the image sensor and an ideal pixel value not affected by blooming.
An image pickup apparatus capable of increasing the dynamic range and performing high-frame rate imaging. The image pickup apparatus includes a pixel section formed by arranging a plurality of pixels each including different types of pixels different in sensitivity to light, in a two-dimensional matrix form. Different types of ADCs perform analog-to-digital conversion of signals read out from the high-sensitivity pixels and low-sensitivity pixels in parallel and hold results in respective counter latch circuits. The pixel section has an interconnection layer including a plurality of interconnections for transferring the signals. One interconnection is used as a vertical read-out line for transferring signals from the low-sensitivity pixels, and another interconnection is used as a vertical read-out line for transferring signals from the high-sensitivity pixels.
In an image capturing apparatus, a subject image is converted into an image signal, which undergoes automatic correction processing including white balance correction processing, and further undergoes image quality change processing. A first evaluation value indicating a largest value of an R signal, a G signal, and a B signal of the image signal undergone the image quality change processing and a second evaluation value indicating a luminance of the image signal undergone the image quality change processing are detected. A control evaluation value is calculated using weighted average of the first evaluation value and the second evaluation value according to at least one of an amount of image quality changing effect due to the image quality change processing and a reliability of the automatic correction processing, and exposure control is performed based on the control evaluation value.
An apparatus may include an image sensor that contains a multiplicity of pixel elements to detect one or more images and a processor circuit coupled to the image sensor. The apparatus may include a white balance module for execution on the processor circuit to receive, based upon a detected image of the one or more images, for a plurality of pixel elements of the multiplicity of pixel elements, three of more gray level values for a respective three or more color channels, to determine grayness likelihood functions for the respective three or more color channels, the three or more grayness likelihood functions comprising a proportional contribution to grey pixels of the detected image from one or more gray levels for each respective color channel, and to determine a white balance gain for two or more color channels based upon the determined grayness likelihood functions. Other embodiments are described and claimed.
An image processing apparatus determines whether a second light source is present with respect to image data, generates, when it is determined that the second light source is present, first image data based on a first white balance correction value and second image data based on a second white balance correction value, and combines the first image data and the second image data according to a determined combination ratio.
An image processing apparatus divides image data captured while a flash light is not emitted into a plurality of areas, calculates color evaluation value for each of the divided areas. The apparatus divides image data captured while the flash light is emitted into a plurality of areas and to calculate color evaluation value for each of the divided areas. The apparatus determines a movement for each of the plurality of areas in accordance with the calculated color evaluation value and the calculated color evaluation value. The apparatus performs white balance processing into image data in accordance with the determined movement.
An apparatus for acquiring a face image using multiple cameras so as to identify a human being located at a remote site is disclosed. The apparatus for acquiring a face image using multiple cameras allows a PTZ camera to track an interest object from among objects detected/tracked by a fixed camera, and obtains an optimum face image for remote human identification from images generated by the PTZ camera. The apparatus for acquiring the face image using multiple cameras so as to identify a human located at a remote site includes a multi-camera control module for tracking an interest object being detected/tracked by a fixed camera through a Pan-Tilt-Zoom (PTZ) camera, and generating an image of the interest object; and a face-image acquisition module for acquiring a face image appropriate for identifying a face image of the remote human in the interest object image generated by the multi-camera control module.
Detecting a pattern in an image by receiving the image of a pattern and storing the image in a memory, where the pattern is composed of shapes that have geometrical properties that are invariant under near projective transforms. In some embodiments the process detects shapes in the image using the geometrical properties of the shapes, determines the alignment of the various shapes, and, corresponds or matches the shapes in the image with the shapes in the pattern. This pattern detection process may be used for calibration or distortion correction in optical devices.
This image capture device includes an image capturing section 100 which captures two images in mutually different exposure times, and an image processing section 220 which performs restoration processing on the images that have been captured by the image capturing section 100. The image processing section 220 includes a blur kernel determining section which determines a blur kernel that defines the camera-shake-induced motion blur of the image captured; and an image restoration section which generates the restored image. The blur kernel determining section changes the size of the blur kernel according to the exposure time in which the image is captured.
Method comprising the steps of: choosing a set of calibration colors within said scene, measuring each calibration color of said set such as to get a set of XYZ to represent each calibration color in the given colorimetric color space, by using said image capture device, capturing calibration colors such as to get a set of Raw RGB values to represent each calibration color, estimating a parametric color transform such that any set of Raw RGB values corresponding to a calibration color is transformed into a set of XYZ values corresponding to the same calibration color, building a color calibration transform by the concatenation of the parametric color transform with an output color transform.
A biological observation apparatus is configured as follows. Namely, the biological observation apparatus includes a marker attached to a living body in order to detect the vibration of the living body, a high-sensitivity camera which forms an observation image of the living body, a high-speed camera which forms an image of light from the marker, and an optical system including a first BA which prevents the light from the marker from entering the high-sensitivity camera.
A method of rendering views for a multi-view display device (100) is disclosed. The multi-view display device (100) comprises a number of display means (104, 110) for displaying respective views in mutually different directions relative to the multi-view display device (100). The method comprises: computing a first motion vector field on basis of a first input image of a time sequence of input images and a second input image of the time sequence of input images; computing a first motion compensated intermediate image on basis of the first motion vector field, the first input image and/or the second input image; and providing the first motion compensated intermediate image to a first one of the number of display means (104, 110).
An image display apparatus and a method for operating the same are disclosed herein. The image display apparatus may include a display to display a 3D image having a left-eye image and a right-eye image, a sensor to detect positions of a first viewing device and a second viewing device for viewing the 3D image, and a controller configured control a perceived view of the 3D image viewed through the viewing devices. The perceived view of the 3D image may be changed based on a position of the viewing devices or the user relative to the display.
A digital display interface (40) connects a first audio-visual device (10) to a second audio-visual device (20). Stereoscopic image data is transmitter over the display interface (40). Components of stereoscopic image data are multiplexed and inserted into an image data carrying element. An existing deep color mode can be re-used for this purpose. Signaling information to help identify or decode the stereoscopic image data is carried in auxiliary data carrying elements. Stereoscopic image data can be distributed between image data carrying data elements and auxiliary data carrying data elements. Auxiliary data carrying elements can be transmitted in horizontal or vertical blanking periods, and can comprise HDMI Data Island Packets. Stereoscopic image data can be sent over an auxiliary data channel. The auxiliary data channel can form part of the same cable as is used to carry a primary channel of the display interface, a separate cable, or a wireless link.
A method and computing system for receiving an indication of a first user participating in a videoconference. A determination is made concerning whether bandwidth compression is preferable for the first user of the videoconference. If bandwidth compression is preferable for the first user of the videoconference: an unprocessed video stream associated with the first user is processed to generate a reduced bandwidth video stream, and the reduced bandwidth video stream is provided to a video encoder. Processing the unprocessed video stream includes performing an edge detection procedure on the unprocessed video stream.
A method and apparatus for widening a viewing angle in a video conferencing system are provided. The apparatus for widening a viewing angle in a video conferencing system includes: generating reference data from images of a video conference participant captured by a camera included in the video conferencing system; generating movement data based on the video conference participant's movements sensed by the camera; extracting a first control parameter by comparing the reference data with the movement data; transmitting the first control parameter to the other end of the conference; receiving a second control parameter generated at the other end of the conference; and controlling the camera by the second control parameter.
An approach for splitting a communication data stream into an audio data stream and a video data stream, anchoring the audio data stream at an anchor point within a network, and bypassing anchoring of the video data stream at the anchor point within the network to reduce a processing load at the anchor point.
A printer apparatus includes a printer body including an opening part that has a protruding part, a support part including a rotary shaft and rotatably attached to the printer body to rotate about the rotary shaft, a platen unit provided in the support part, and a shaft bearing including a projecting part and rotatably supports the platen roller. The opening part receives the shaft bearing. In a state where the platen unit is installed in the printer body, the projecting part and the protruding part contact each other. In a case of removing the platen unit from the printer body, the shaft bearing and the support part rotate in a same direction.
Device to reproduce images or graphical patterns in general on large surfaces, comprising at least a printing system (14) mobile in at least one direction with respect to a support frame (12)>> an optical viewing system (100) associated with the support frame (12) and able to recognize the position of the portion of image already executed, and to recognize possible reference signs affixed in the step when said portion of image was executed, in order to allow the correct positioning of the device so as to execute the adjacent portion of image that has to be executed next.
A first sub-pixel, a second sub-pixel and a third sub-pixel of a pixel are utilized to display a first white image, then a first brightness of the first sub-pixel and a first brightness of the second sub-pixel are measured. The first sub-pixel, the second sub-pixel and a fourth sub-pixel of the pixel are utilized to display a second white image, then a second brightness of the first sub-pixel and a second brightness of the second sub-pixel are measured. How image data should be displayed is determined according to whether the first brightness of the first sub-pixel is greater than the second brightness of the first sub-pixel, whether the first brightness of the second sub-pixel is greater than the second brightness of the second sub-pixel, and whether a chromaticity coordinate of the image data is within a chromaticity range capable of being displayed by the first, second and third sub-pixels.
The present invention relates to an organic light emitting diode display device capable of sensing driving current of each pixel with a simple configuration to compensate for a luminance deviation between pixels and a pixel current sensing method thereof. The organic light emitting diode display device includes a display panel including 2N (N being a natural number) pixels that share a reference line though which a reference signal is supplied and are respectively connected to 2N data lines through which data signals are applied, and a data driver for driving the 2N pixels sharing the reference line in a time division manner through the data lines, sensing currents of the time-division-driven 2N pixels as voltages through the shared reference line and outputting the sensed currents, in a sensing mode.
Methods and systems for color grading video content are presented. A component (e.g. a frame, a shot and/or a scene) of the video content is designated to be a master component and one or more other components of the video content are designated to be slave components, each slave component associated with the master component. A master component color grading operation is performed to the master component. For each one of the slave components, the master component color grading operation is performed to the slave component and a slave color grading operation that is specific to the one of the slave components is also performed. Metadata, which form part of the video content, are created to provide indicators on to whether components of the video are designated as master or slave components.
A technique to enable information sharing among agents within different cache coherency domains. In one embodiment, a graphics device may use one or more caches used by one or more processing cores to store or read information, which may be accessed by one or more processing cores in a manner that does not affect programming and coherency rules pertaining to the graphics device.
A system, method and computer readable medium for converting paper documents to electronic documents and sending the electronic documents to at least one destination, involves receipt from a remote server of user interface information which provides a user interface for enabling the user to designate a destination of the electronic document, local display of the user interface in accordance with the user interface information, and dissemination of a destination as designated by the user via the displayed user interface.
In an embodiment, a processor that includes multiple cores may implement a power/performance-efficient stop mechanism for power gating. One or more first cores of the multiple cores may have a higher latency stop than one or more second cores of the multiple cores. The power control mechanism may permit continued dispatching of work to the second cores until the first cores have stopped. The power control mechanism may prevent dispatch of additional work once the first cores have stopped, and may power gate the processing in response to the stopping of the second cores. Stopping a core may include one or more of: requesting a context switch from the core or preventing additional work from being dispatched to the core and permitting current work to complete normally. In an embodiment, the processor may be a graphics processing unit (GPU).
Systems and methods are provided for drawing shapes with minimal user interaction. A drawing area is displayed, and a shape selection component comprising a set of shape selection regions is displayed. Each shape selection region is associated with a shape that can be drawn, and includes a selection component for selecting the shape, and a drawing component for initiating a drawing of the shape. First data indicative of a selection of a first selection component of a first shape selection region from the set of shape selection regions is received. Second data is received that is indicative of a selection of a first drawing component of the first shape selection region. A representation of a first shape associated with the first shape selection region on the drawing area is drawn, in response to the first data and the second data, wherein the representation can be manipulated.
A computer-readable recording medium storing an information display program for causing a computer to execute a process, the process includes: identifying a first component related to a first character string extracted, referring to a first storage unit that stores a plurality of components constituting the article and character strings that individually represent the plurality of components; obtaining first location information related to the first component from a second storage unit that stores pieces of location information corresponding to the plurality of components in the article; determining an eye direction when a shape of the article is displayed; determining second location information of the first component in the shape of the article related to the eye direction, based on the first location information and the eye direction; and displaying the first character string based on the second location information.
Visually representing a composite graph of image functions includes providing a visual representation of a composite graph for an image, the visual representation including first items corresponding to respective image functions, and second items corresponding to containers for image functions, the image to be rendered by performing the image functions in an order defined by the composite graph. The user selects an expansion mode for presenting contents of a first container, each of the containers having a first expansion mode wherein the contents are displayed generally adjacent the visual representation, and a second expansion mode where the contents are displayed generally within the visual representation. A modified visual representation of the composite graph is provided in response to the input, wherein the modified visual representation maintains the order of the image functions defined by the composite graph and has the first container expanded according to the selected expansion mode.
Provided are a method and apparatus for processing a graphic stream. The method may include determining whether a graphic picture is reproducible as a three-dimensional (3D) image by assigning different depth values according to graphic objects or by assigning the same depth value to the graphic picture, using 3D capability information.
3D image data can be modified based on user preference data received from a user. The user preference data may be received at a first device and used to adjust 3D image data generated by the first device for presentation by a display device, or the first device may receive the user preference data and transmit it to a display device such that the display device may adjust the 3D image data based on the user preference data. The 3D image data may be adjusted based on user preference data to support presentation of 3D imagery on the display device in a manner desired by a user. 3D user viewing preferences may include an amount of pop-out effect in images, a stereo baseline of images, a depth range of images, a spatial distribution of images, a degree of depth sharpness in images, or specification of a user's dominant eye.
A method, system, apparatus, article of manufacture, and computer-program product provides the ability to generate a cross section for a roadway infrastructure model. A cutting plane line is drawn on the roadway infrastructure model at an arbitrary location. Portions of the roadway infrastructure model that intersect the cutting plane line are determined. Solids are created at the intersections. A cross section is formed by slicing the one or more solids based on the cutting plane line. The cross section is displayed.
A level shifter circuit, wherein a first and a second transistor circuit are connected serially, a third and a fourth transistor circuit are connected serially; a first input voltage is applied to the second transistor circuit and a second input voltage is applied to the fourth transistor circuit; an input terminal of the first transistor circuit is connected to an output terminal of the third and the fourth transistor circuits, and an input terminal of the third transistor circuit is connected to an output terminal of the first and the second transistor circuits; two transistor circuits of at least one side of two transistor circuits of a first fixed power source side and two transistor circuits of a second fixed power source side are configured of double gate transistors; and the level shifter circuit has a switch element for applying a voltage to a common connection node.
The present invention relates to a display device that measures display characteristics (such as luminance or chromaticity) associated with a display panel. The display device of the present invention has a light sensor (5) provided at a position allowing outgoing light from a screen (1a) of a liquid crystal panel (1), which serves as the display panel, and extraneous light reflected on the screen (1a) to enter the light sensor (5). Since the light sensor (5) is provided at the position, it is possible to measure the characteristics of the display panel and also the characteristics of the extraneous ambient light reflected on the screen. Thus, it is possible to accurately adjust the display characteristics based on the measurement results.
An optical touch display panel includes a plurality of light-sensing touch units and a position detecting circuit. Each light-sensing touch unit includes a light-sensing component, a storage capacitor, a signal reading component, and a charging component. The light-sensing component senses a light source to generate a sensing signal. The storage capacitor is connected electrically to the light-sensing component for storing the sensing signal. The signal reading component is connected electrically to the storage capacitor for reading a voltage of the storage capacitor to generate a reading signal. The charging signal is connected electrically to the storage capacitor for charging the storage capacitor to reset an electric charge record of the storage capacitor. The position detecting circuit is connected electrically to the light-sensing touch units for detecting a touch point on the optical touch display panel according to a reading signal output by each of the light-sensing touch units.
A power-saving sensing module includes a light source, a first and a second sensor, a first and a second detection unit, and a controller. The first sensor detects a touch of an external object to generate a first sensing signal corresponding to the touch. The first detection unit generates a touch signal corresponding to the first sensing signal. The second sensor senses a second sensing signal corresponding to the external object in response to the light ray. When the touch signal is greater than a touch threshold value, the second detection unit outputs a displacement signal corresponding to the second sensing signal. The controller outputs a control signal in response to the touch signal of the first detection unit and the touch threshold value, so that the second detection unit operates at a dormant state or a sensing state in response to the control signal.
A multi-display system that uses back lights and light guides of an electronically addressable display to provide position-unique signals that both uniquely identify positions on a given display, but also uniquely identify displays within a multi-display system.
A processing system for capacitance sensing includes a sensor module and a determination module. The sensor module includes sensor circuitry coupled to sensor electrodes, the sensor module configured to generate sensing signals received with the sensor electrodes. The determination module is connected to the sensor electrodes and configured to obtain, for a predetermined timeframe, a profile from the sensing signals, obtain, for the predetermined timeframe, a noise statistic, and calculate, for the predetermined timeframe, a data signal statistic for the predetermined timeframe using the profile. The determination module is further configured to calculate a signal to noise ratio (SNR) by dividing the data signal statistic by the noise statistic. When the SNR satisfies a predetermined detection threshold, an input object is detected in a sensing region of the capacitance sensing input device.
A user interface enabling a user to operate without viewing a screen is generated. An input apparatus 10 according to the present invention includes a touch sensor 103 configured to detect an input position of a touch input, a load detection unit 105 configured to detect a pressure load applied on a touch face of the touch sensor 103, and a control unit 104 configured to, when the load detection unit 105 detects a pressure load satisfying a predetermined standard load, control to generate a virtual user interface having a home position key arranged at the input position.
A portable device and method of manufacturing a display device includes a display panel having a glass substrate and a polarizer adhered to the glass substrate, a touch panel which is made of resin material and adhered to the polarizer of the display panel by a first adhesive material, and a front window which is made of glass and adhered to the touch panel by a second adhesive material. One of the first adhesive material and the second adhesive material is an adhesive sheet, and an other of the first adhesive material and the second adhesive material is an ultraviolet-curing adhesive material.
A portable terminal operates while switching first mode for generating, based on a value indicating a degree of contact output by a touchpad, a value indicating degree of the contact for each contacted area and second mode for generating, based on the output value, a value by performing adjustment such that temporal change amount of the value indicating the degree is equal to or less than a predetermined value. When a value of one contacted area generated in the second mode equals or exceeds the first threshold, the portable terminal switches to the first mode, and when a value of one contacted area generated in the first mode falls below the second threshold, the portable terminal switches to the second mode. The portable terminal determines, as a target area to which processing to be performed is allocated, one contacted area having a value that equals or exceeds the first threshold.
The present invention introduces a 3D computer cursor that helps the user to interact with 3D computer applications in an intuitive manner. Said 3D computer cursor enables the user to easily manipulate a plurality of windows, objects, or the like to be moved or rotated in three dimensions on the computer display serving a variety of desktop and web-based applications.
A method, including receiving, by a computer executing a non-tactile three dimensional (3D) user interface, a set of multiple 3D coordinates representing a gesture by a hand positioned within a field of view of a sensing device coupled to the computer, the gesture including a first motion in a first direction along a selected axis in space, followed by a second motion in a second direction, opposite to the first direction, along the selected axis. Upon detecting completion of the gesture, the non-tactile 3D user interface is transitioned from a first state to a second state.
An accelerometer and a magnetometer of a mobile computing device are operable to provide a first input and a second input, respectively, to an orientation module that uses signals to determine a spatial orientation of the mobile computing device. The orientation module receives the first input from the accelerometer and the second input from the magnetometer; determines two or more angles of incidence relative to two or more planes; determines a relative accuracy of the first input and the second input in predicting device orientation at the two or more angles of incidence; assigns weightings to the first input and a second weighting to the second input based on the relative accuracy of the first input and the relative accuracy of the second input; and determines an orientation of the mobile computing device based on the first weighting of the first input and the second weighting of the second input.
There is provided an input device, including: a base; an operation portion; and an oscillatory wave motor including a stator and a rotor, the rotor thrusting the stator, the oscillatory wave motor providing haptic feedback to an operator via the operation portion. Displacement of one of the stator and the rotor from the base in an axial direction is allowed, displacement of the one of the stator and the rotor in a rotational direction is restricted, and the operation portion includes the other one of the stator and the rotor.
An apparatus, and an associated method, forms a user interface permitting input of input instructions to an electronic device. Input commands are evidence by tactile input forces applied to a force receiving surface. Force sensing elements are positioned to sense indications of the tactile input force. The force sensing element is caused to exhibit a selected input parameter value through application of a selected force thereto by application of a tightening torque to a fastener positioned in proximity to the force sensing element.
An organic light emitting display, and an image modification method may include an analog to digital image signal processor configured to output present digital image data, a frame data analysis unit electrically coupled to the image signal processor, the frame data analysis unit configured to receive the present digital image data and a present data summation value, and to output a new data summation value, a light emission time supply unit electrically coupled to the frame data analysis unit and configured to supply a light emission time in accordance with the new data summation value, and a light emission control driver electrically coupled to the light emission time supply unit and configured to output a light emission signal in accordance with the light emission time output from the light emission time supply unit.
The present disclosure relates to a metamaterial for diverging an electromagnetic wave, which comprises at least one metamaterial sheet layer. Refractive indices of the metamaterial sheet layer are distributed in a circular form with a center of the metamaterial sheet layer, and the refractive indices remain unchanged at a same radius and increase gradually with the radius. The present disclosure changes electromagnetic parameters at each point of the metamaterial through punching or by attaching man-made microstructures so that the electromagnetic wave can be diverged after passing through the metamaterial. The metamaterial of the present disclosure features a simple manufacturing process and a low cost, and is easy to be implemented. Moreover, the metamaterial of the present disclosure has small dimensions and does not occupy a large space, so it is easy to miniaturize apparatuses made of the metamaterial of the present disclosure.
There is provided an antenna pattern frame including: a radiator comprising an antenna pattern portion transmitting and receiving a signal and a connection terminal portion allowing the signal to be transmitted to and received from a circuit board of an electronic device; and a radiator frame manufactured by injection molding on the radiator, allowing the antenna pattern portion to be embedded in a case of the electronic device, and supporting the radiator. The radiator frame includes a hydraulic recess introducing a resin material to a mold for manufacturing a case of the electronic device in which the radiator is embedded through injection molding, so that the radiator frame contacts the mold by injection pressure.
An antenna implementation comprises an electromagnetic lens and at least one electromagnetically shielding member. The electromagnetic lens is adapted to guide at least one electromagnetic signal by means of at least a variation in permittivity. The at least one electromagnetically shielding member encapsulates the electromagnetic lens partially so as to direct at least one electromagnetic signal propagating through the electromagnetic lens. The at least one electromagnetically shielding member can advantageously be part of an enclosure; said enclosure encapsulates partially the electromagnetic lens. The antenna can further comprise antenna transmission means that contain wave guides. Said waveguides can advantageously be incorporated into the enclosure. The antenna is particularly suited for implementations using Substrate Integrated Waveguide techniques. SIW techniques allow miniaturization of the antenna and offer the advantage of low energy consumption as may be required in portable devices.
A five-band Bluetooth built-in antenna and its mobile communication terminal provide bandwidth for communication. A built-in antenna comprises an antenna radiation unit and a first slot, a second slot and a third slot. Slots are added to approach a center frequency of a low-frequency branch part of the antenna so that the antenna generates resonance, so the low-frequency bandwidth of the antenna is increased. A high-frequency part of the antenna generates resonance by means of capacitive coupling.
Devices, systems, and methods for sending positional information from transmitters/beacons are disclosed. In one implementation a transmitter generates a range block including a ranging signal and a hybrid block including positioning data, and sends the range block and hybrid block in predefined slots in a transmit frame. A receiver in a user device receives signals from a plurality of transmitters and generates position/location information using trilateration and measured altitude information in comparison with transmitter altitude information.
A rover processor determines position of a rover based upon the interaction between multiple antennas located at the rover and multiple antennas located at a base. The rover antennas may include a rover master antenna having a phase center located at the centroid of the antennas patterns of at least two auxiliary rover antennas. The rover processor may determine the position of the rover master antenna based upon the relative positions of at least two rover antennas (e.g., the rover master antenna and at least one rover auxiliary antenna, or at least two rover auxiliary antennas) with respect to at least two antennas of a base transceiver.
Assisted-GPS for a portable biometric monitoring device is provided. The portable biometric monitoring device may obtain updated ephemeris data from an associated secondary device via a short-range, low-power communication protocol. The secondary device may be a computing device such as a smartphone, tablet, or laptop. Various rules may control when the ephemeris data is updated. The ephemeris data may be used in the calculation of the global position of the portable biometric monitoring device. Additionally, the portable biometric monitoring device may communicate downloaded position fixing data to the associated secondary device. The associated secondary device may then calculate the global position from the position fixing data.
Provided is a technique capable of suppressing the deterioration in azimuth resolution and distance resolution in even a modulated and transmitted or received signal or a signal reflected by an object and varied in intensity when acquiring waveform information. A measurement device comprise: a plurality of sensors which receive waves propagating through a space; and a sampling timing calculation means which obtains, on the basis of the relative positions of the sensors and the velocities of the waves, the difference between the arrival times of the waves received by the respective sensors and calculates, for each sensor, sampling timing for acquiring the waveform information relating to the waves, on the basis of the difference between the arrival times.
The architecture includes a passive radar using opportunistic transmitters and a plurality of active radars that cooperate in the form of a coalition to assure the surveillance of an area of space. The passive radar and the active radars that form the architecture include means for exchanging information and the passive radar is configured to adopt two alternate operating modes: (i) a “watching” mode in which the passive radar carries out surveillance of the area of space concerned and generates detection information, and (ii) an “on-demand data feed” mode in which the passive radar executes at the request of one or more active radars an object search in a given sector of the area under surveillance or an analysis of certain characteristics of the signal received in a given sector.
An apparatus includes a first circuit and a second circuit. The first circuit may be configured to generate a reduced representation of an input sequence of characters by replacing a repetition of a sequence of one or more characters by a code representing the repetition of the sequence of one or more characters. The second circuit may be configured to generate a compressed representation of the input sequence of characters in response to the reduced representation of the input sequence of characters. The second circuit is generally configured to recognize the code representing the repetition of the sequence of one or more characters and take into account the repetition of the sequence of one or more characters during a compression operation.
A power safety system is configured to provide power information in an aircraft. The power safety system includes a power safety instrument having a power required indicator and a power available indicator, each being located on a display. A position of the power required indicator and the power available indicator represent the power available and power required to perform a hover flight maneuver. The power safety system may be operated in a flight planning mode or in a current flight mode. The power safety system uses at least one sensor to measure variables having an effect on the power required and the power available.
A method and system for activity monitoring of a user are disclosed. In a first aspect, the method comprises calibrating posture by the user to determine a calibration vector. The method includes validating the calibration vector by comparing an anteroposterior axis to a threshold, wherein activity of the user is monitored using the validated calibration vector. In a second aspect, a wireless sensor device comprises a processor and a memory device coupled to the processor, wherein the memory device includes an application that, when executed by the processor, causes the processor to receive a posture calibration request from the user and to determine a calibration vector based on the received request. The application, when executed by the processor, further causes the processor to validate the calibration vector by comparing an anteroposterior axis to a threshold, wherein activity of the user is monitored using the validated calibration vector.
A real time telemetry system is disclosed for use with a drilling system including a rotary valve 28 controlling the supply of drilling fluid or mud to a downhole tool. The system comprises receiving data to be transmitted, encoding the data as a duration, and controlling the rotation the rotary valve 28 such that the rotary valve 28 is rotated for the said duration at a predetermined rotary speed to cause the formation of pressure fluctuations or waves in the drilling fluid or mud.
A method, device and/or a system of centralized management and emergency allocation of deployed defibrillators each having associated communication modules. A central server may process a message from a communication module associated with a defibrillator, and then analyze a photograph and/or a video of a defibrillator display to compare it to a set of expected visual markers using a pixel algorithm of a pixel analysis module. The central server may then determine the operational status of the defibrillator such as whether it is in a nonfunctional status. The central server may then send alerts to the communication module and notifications to the an organization owning or leasing the defibrillator. The central server may also send alerts to the communication module based on a nearby emergency call, provide geospatial mapping of defibrillators to improve deployment efficiency and/or establish bi-directional communication between the operator of the defibrillator and a medical professional.
A device that causes a driver not to feel passive task-related fatigue by performing interaction with the driver at a time when the driver feeling passive task-related fatigue, thereby promoting safe driving. In particular, phrase “the interaction with the driver” refers to a series of operations viewing quiz data or beat sequence data to the driver, receiving a response, and visually, acoustically, and tactilely informing a result according to the response, and a control of each component for the operation.
Methods and systems for monitoring a well-being of a target are disclosed. In a method embodiment, data representing a process electric potential signal is received by a computer system. The process electric potential signal may be generated at least in part by one or more electric potential sensors in response to the detection of a change in an electric field of a target spaced apart from the one or more electric potential sensors. The method may further include identifying, using the computer system and based at least in part on the data electronically received by the computer system, a recurring pattern in the received data. The method may also include determining, using the computer system and based at least in part on the received data, whether a deviation from the recurring pattern transgresses a threshold. The deviation may comprise a subset of the data electronically received by the computer system.
Computer-based systems and computer-implemented methods are described for monitoring medication events for an individual. Computer-based systems include systems for monitoring medication events relating to an individual, including: circuitry for analyzing data for an identifier of a first medication event for an individual; circuitry for analyzing the data for at least one attribute of an individual; circuitry for analyzing the data for at least one attribute relating to a medication during the first medication event; circuitry for analyzing the data for at least one feature of visual information and at least one feature of non-visual information relating to the individual during the first medication event; circuitry for analyzing the received data for a time associated with the first medication event; circuitry for determining a compliance likelihood for the first medication event based on the analyses of the received data; and circuitry for indicating the determined compliance likelihood.
An intruder barrier is provided that includes multiple generally parallel transparent slats acting as burglar bars with at least some, and preferably all, of the transparent slats having associated therewith a conductive path extending at least from a first end region of a slat to a second end region thereof. The conductive path is capable of conducting electricity or electromagnetic radiation along the length of the slat and is associated with an output to an alarm system that may be configured to trigger an alarm when the conductive characteristic of a slat is terminated by virtue of the slat being at least partially severed, broken, or removed from its operative position. Typically the transparent slats are secured to a fixed surrounding frame of an opening window. The invention in a further embodiment includes transparent slats for use in such an intruder barrier. The invention in a further embodiment includes a laterally collapsible latticed intruder barrier comprising multiple transparent slats interconnected with each other and having such conductive paths.
A load control system controls an electrical load provided in a space and comprises a load control device and one or more occupancy sensors. The load control device controls the load in response to the wireless control signals received from the occupancy sensors. Each occupancy sensor transmits an occupied control signal to the load control device in response to detecting an occupancy condition in the space and a vacant control signal to the load control device in response to detecting a vacancy condition. The load control device turns on the load in response to receiving the occupied control signal from at least one of the occupancy sensors, and turns off the load in response to receiving vacant control signals from both of the occupancy sensors. The load control device is operable to determine that no wireless control signals have been received from the occupancy sensors for the length of a predetermined timeout period and to subsequently turn off the load.
A peer to peer surveillance architecture comprising a plurality of independent nodes for capturing, analyzing, storing, and viewing surveillance information is disclosed. The surveillance architecture has no central controller or single point of failure because of the peer to peer or independent relationship between its nodes. Generally, surveillance information of various types is captured by one or more capture nodes and transmitted to or one or more viewing, content storage, or server nodes for display, analysis, storage, or a combination thereof. Server nodes may provide authentication services to validate user or device credentials prior to granting access to surveillance information. In one or more embodiments, specialized video compression hardware is provided to allow high quality video surveillance information to be transmitted across low bandwidth connections. Compression may also be performed on other types of surveillance information.
In a method for controlling a car using a car key, a selected function is received from a function menu displayed on an operation interface of a display device of the car key. System data about the car is acquired from a management unit of the car, and devices of the car are controlled using the management unit, according to the selected function. The system data about the car or status of the devices of the car is displayed on the operation interface of the display device.
An approach warning system includes at least one marking module and a warning module. The at least one marking module comprises a marking module transmission unit configured to emit electromagnetic signals, and a motion detector configured to detect a motion. The at least one marking module is configured to emit presence signals as the electromagnetic signals when a motion is detected. The warning module comprises a reception unit configured to receive the electromagnetic signals emitted by the at least one marking module, and an output device configured to emit an approach warning. The warning module is configured to emit the approach warning via the output device dependent on a reception of the presence signals emitted by the at least one marking module.
A method and a device for driver information, according to which a warning is produced on the basis of the lane information which indicates crossing of the lane edge. Upon branching of a roadway line, the particular outer lines are used as lane edge markings as the basis for the lane departure warning.
A vehicular exterior rearview mirror system includes an exterior rearview mirror assembly having a mirror reflective element that is fixedly attached at a mirror back plate. The mirror back plate includes an indicator structure that has a passageway that extends from the back plate at an angle relative to the portion of the back plate. At least one baffle is disposed within the passageway and is angled at the angle relative to the portion of the back plate. An indicator is mounted at an end portion of the passageway, and light emitted by the indicator passes through the passageway and through the mirror reflective element via an opening in the back plate. When the indicator is activated, light passing through the passageway and emanating from the mirror reflective element is at least partially shielded from direct view by the driver of the vehicle by the at least one baffle.
A communication power line status detecting method and a system using the method provided by the present disclosure is suitable for used in a transmission device and a receiving device which are connected by a communication power line. The transmission device transmits a communication indicator signal through the communication power line. When the receiving device receives the communication indicator signal from the communication power line, it converts the communication indicator signal into a time domain in order to analyze the signal reflection and transmission status of the communication indicator signal when it is transmitted via the communication power line, and to generate a line status information corresponding to the communication power line.
A method for collision avoidance in a multi-reader environment comprising a plurality of Radio Frequency Identification (RFID) interrogators, the method comprises each of the plurality of interrogators entering a quiet state during which none of the interrogators transmits, each of the plurality of interrogators selecting a transmit time after the quiet period during which each of the interrogator will attempt to transmit, each of the plurality of interrogators monitoring their associated receive path, an interrogator of the plurality of interrogators transmitting an instruction during its selected transmit time indicating the beginning of a session when the interrogator does not detect data on its receive path prior to its select transmit time, the interrogator comparing its receive path to its transmit path when it transmits the instruction, the interrogator returning to the quiet state when the receive path does not match the transmit path, and the interrogator completing the session when the receive path matches the transmit path.
Embodiments of the present invention provide novel techniques for creating a high speed transformer such as a pulse transformer. In particular, a secondary coil of the high speed transformer may include a single turn. The use of a single turn secondary coil simplifies the design and manufacture of the transformer and aids in more efficient inspections. Further, the single turn secondary coil transformer may reduce the number of vias used to interconnect the components of the transformer. Additionally, the embodiments described herein may significantly improve voltage isolation by single turn coils, and eliminate vias between board layers.
A magnetic device is provided. The magnetic device includes a magnetic core and a conductive winding inductively coupled to the magnetic core. The conductive winding includes a first terminal segment, a second terminal segment, and an inductive segment electrically coupled in series therebetween. The first terminal segment includes a current sensing element.
A linear actuator includes a first tube, a second tube inserted into the first tube to be free to slide, a rod fixed at one end of the rod to the first tube, a rod guide provided on the other end of the rod so as to slide relative to the second tube, a plurality of permanent magnets held by the rod, a holder that is fitted into the second tube and holds a plurality of coils, a first chamber defined between one end of the holder and an end portion of the first tube, and a second chamber defined between the other end of the holder and the rod guide. An insertion hole which connects the first chamber to the second chamber and through which the rod passes is formed in the holder. A connecting groove that connects the first chamber to the second chamber is formed in the second tube to extend in an axial direction.
In a multilayer band pass filter, via-electrodes and strip electrodes define inductors of LC parallel resonators in four stages. A capacitor electrode and a ground electrode define a capacitor of a first-stage LC parallel resonator. A capacitor electrode and the ground electrode define a capacitor of a fourth-stage LC parallel resonator. Capacitor electrodes define a second-stage LC parallel resonator. Capacitor electrodes define a third-stage LC parallel resonator. Among four or more of the LC parallel resonators, the coupling between certain LC parallel resonators is easily defined, and the attenuation characteristic of a filter is definable with a high degree of freedom.
A transmission line is provided in which a first portion of the transmission line is configured to be connected to a source, and a second portion of the transmission line is configured to be connected to a load. A capacitive element is coupled to the transmission line and is configured to compensate for an impedance difference between the load and at least one of the source or the transmission line, at a frequency within a frequency bandwidth of the load. A difference between an internal capacitance of the first portion of the transmission line and the second portion of the transmission line substantially matches the capacitance of the capacitive element.
A balun including a first conductor winding, a first inductor, a second inductor, a third inductor, and a fourth inductor. The first conductor winding has a figure eight shape including a first loop and a second loop. The first inductor and the second inductor substantially surround the first loop. The third inductor and the fourth inductor substantially surround the second loop.
A vibration element includes a piezoelectric substrate including a vibrating section and a thick section having a thickness larger than that of the vibrating section. The thick section includes a first thick section provided along a first outer edge of the vibrating section, a second thick section provided along a second outer edge, and a third thick section provided along another first outer edge. An inclined outer edge section that intersects with each of an X axis and a Z′ axis is provided in a tip section of the piezoelectric substrate.
A ring-oscillator-based on-chip sensor (OCS) includes a substrate having a semiconductor surface upon which the OCS is formed. The OCS includes an odd number of digital logic stages formed in and on the semiconductor surface including a first stage and a last stage each including at least one NOR gate including a first gate stack and/or a NAND gate including a second gate stack. A feedback connection is from an output of the last stage to an input of the first stage. At least one discharge path including at least a first p-channel metal-oxide semiconductor (PMOS) device is coupled between the first gate stack and a ground pad, and/or at least one charge path including at least a first n-channel metal-oxide semiconductor (NMOS) device is coupled between the second gate stack a power supply pad.
A variable gain amplifier (100) includes a transistor (110), an FB impedance section (120), a source impedance section (130), a drain impedance section (140), a gain controller (150), and a frequency characteristic controller (160). The gain controller (150) varies impedance of one of the FB impedance section (140), the source impedance section (130), and the drain impedance section (140), and outputs a gain control signal. The frequency characteristic controller (160) varies the impedance of different impedance section, based on the gain control signal.
Embodiments include systems and methods for accurately controlling gain of a high-speed variable-gain amplifier (VGA) without adversely impacting bandwidth performance. Embodiments include a VGA with a variable resistor, for which resistance is a function of a control level. A gain calibration system controls the control level by using a gain control feedback subsystem to sample outputs of a duplicate VGA, which includes a duplicate variable resistor. The sampled duplicate outputs are compared to a target gain generated by a reference generator. The control level can be fed back to control the gain of the duplicate VGA until the target gain is reached. The control level can also be fed to the actual VGA to control its gain. By performing gain control on the duplicate VGA without interfering with the output signal path of the actual VGA, the actual VGA's gain can be accurately controlled without impacting its bandwidth.
A gate drive circuit is disclosed that charges the gate of a switching transistor to a voltage that is high enough to turn the switching transistor fully on and then prevent the charge from flowing back into the gate drive circuit. The gate drive circuit works with a ground rectifier switch by providing a fully differential connection of the switching transistor and its capacitor and resistor in parallel with the antenna.
A thermal controller for driving a gate control unit of a gate-driven semiconductor switching device, the thermal controller comprising a junction temperature estimation module for generating an estimated junction temperature for the switching device, a gate voltage control module for modifying a gate voltage of the switching device, a switching frequency control module for modifying a switching frequency of the switching device, and a duty cycle control module for modifying the duty cycle of the switching device. In use, the thermal controller is adapted to activate one of the gate voltage control module, switching frequency control module and duty cycle control module dependent upon the estimated junction temperature in order to maintain the actual junction temperature below a pre-determined limit.
A method and apparatus for single port modulation of a phase locked loop frequency modulator includes a phase locked loop with a voltage controlled oscillator (VCO) and a integer loop for multiplying up the output of the VCO which is divided by a fractional-N modulator and divider in the feedback control. The integer loop enables the use of a high frequency reference oscillator that allows a closed loop response of the phase locked loop having a bandwidth that is wider than the modulation bandwidth.
Embodiments described herein provide approaches for improving a standard cell connection for circuit routing. Specifically, provided is an IC device having a plurality of cells, a first metal layer (M1) pin coupled to a contact bar extending from a first cell of the plurality of cells, and a second metal layer (M2) wire coupled to the contact bar, wherein the contact bar extends across at least one power rail. By extending the contact bar into an open area between the plurality of cells to couple the M1 pin and the M2 wire, routing efficiency and chip scaling are improved.
A method and apparatus that controls the clock of a digital circuit, and therefore power consumption, without substantially comprising performance is provided. The apparatus may include monitoring the utilization of a First in First Out (FIFO) buffer. For example in a systems and methods according to the invention, clock speed may be reduced when the FIFO is relatively empty and increased when the FIFO is relatively full. The clock speed may be controlled by a phase locked loop, a clock divider, a clock masking device or a combination of more than one of these methods. Power reduction may also be obtained by controlling the clocking of different stages of a pipelined device. One or more aspects of the inventions may be implemented in combination with other aspects of the invention to further reduce power use.
A transceiver includes a transmitter and receiver that form a series current path between two power-supply nodes. Powering both the transmitter and receiver with the same supply current saves power. The transmitter functions as a resistive load for the receiver, and thus performs useful work with power that would otherwise be dissipated as waste heat.
A system and method for in-process yield evaluation and correction in an array type of device are provided. The system and method include measuring electrical resistance between individual GATE lines, DATA lines, a DATA bus I/O pad, and a GATE bus I/O pad; and analyzing the measured electrical resistance to identify at least one of the following: GATE line open defects, GATE line bridge defects, DATA line open defects, DATA line bridge defects, and interlayer shunt defects.
A digital communications test system and method for testing a plurality of devices under test (DUTs) in which multiple sets of a single vector signal analyzer (VSA) and single vector signal generator (VSG) can be used together to perform error vector magnitude (EVM) measurements for one or more DUTs in parallel, including one or more of composite, switched and multiple input multiple output (MIMO) EVM measurements. This allows N pairs of a VSA and VSG to test N DUTs with N×N MIMO in substantially the sane time as a single VSA and VSG pair can test a single DUT, thereby allowing a substantial increase in testing throughput as compared to that possible with only a single VSA and VSG set.
In one embodiment, a method comprises driving one or more drive electrodes formed on a substrate with one or more drive signals. A wiper comprising at least one arm is driven to a predetermined voltage. The wiper is electrically insulated from a plurality of sense electrodes formed on the substrate. For each sense electrode of the plurality of sense electrodes, a charge stored by the sense electrode is detected. A processor determines a position of the wiper based on the detected charges stored by the plurality of sense electrodes.
A device and a method for the capacitive detection of an object which is preferably arranged behind a flat article that is transparent to electromagnetic radiation or a wall, including a sensor incorporating sensor electrodes for the detection of the object, preferably for the detection of relative movements between the sensor and the flat article or a finger, where a control circuit serves for the control of the sensor electrodes and for the evaluation of the output signals of the sensor, and, due to the fact that the sensor comprises at least one sensor electrode which is surrounded by at least one further electrode, the surrounding further electrode is connected to the sensor electrode by the control circuit in such a manner that, in the event of a change of the potential of the sensor electrode, the potential of the surrounding further electrode is regulated in the opposite sense to the sensor electrode in such a way that the sensor electrode remains at a pre-determined or pre-definable potential, such that there is produced a capacitive sensor which does not react to tilting or small changes in the spacing from the surface.
The present disclosure is directed to a voltage-to-current sensing circuit having a bias terminal configured to receive a reference voltage, an offset terminal configured to receive an offset current, and an operational amplifier configured to output a low voltage signal. The device includes a first amplifier having first and second high voltage inputs configured to receive a first voltage difference across a sense component on a high voltage line and to generate a first current, a second amplifier having first and second low voltage inputs configured to receive a second voltage difference between the bias terminal and the offset terminal and to generate a second current, a summing circuit configured to provide an intermediate voltage corresponding to a sum of the first and the second currents, and a low-voltage transistor coupled to an output of the amplifier and controlled by the intermediate voltage to generate the output current.
Circuits and processes for detecting a peak value of an input signal are disclosed. In one example, a peak detector circuit may sample a line sense signal, determine the peak value of the line sense signal during a search window, and output a peak detection signal representative of the determined peak value. In a first mode, the peak detector circuit may cause the peak detection signal to be representative of the determined peak value from an immediately preceding search window. In a second mode, the peak detector circuit may cause the peak detection signal to follow the sampled line sense signal. The peak detector circuit may operate in the second mode in response to the sample of the line sense signal being greater than a peak value of the line sense signal from an immediately preceding search window by more than a threshold amount.
Circuits and methods to compensate leakage current of a LDO are disclosed. The compensation is achieved by a temperature dependent sink current generation, which has a nearly zero current consumption increase of about 50 nA at room temperature and starts sink current at temperatures about above 85 to 100 degrees Celsius, which is corresponding to a range of temperature wherein leakage currents come into account.
Temperature characteristics of battery cells are detected. In accordance with one or more embodiments, an intercept frequency is detected for each battery cell, at which frequency an imaginary part of a plot of impedance values of the battery cell exhibits a zero crossing. The impedance values correspond to current injected into the cell. A temperature of the cell is determined based upon the detected intercept frequency for the cell and stored data that models operation of the cell. Various approaches are implemented with different types of circuits coupled to detect the impedance values of the respective cells.
A boost converter control apparatus for controlling a motor drive system which is provided with a boost converter disposed between an electric power converter and a direct current power supply, the boost converter boosting a direct current voltage of the direct current power supply and supplying it to the electric power converter, is provided with: an operating device provided with a proportional element, an integral element and a derivative element, the derivative element being configured as a bandpass filter, the operating device calculating a PID controlled variable corresponding to an electric current command value of the boost converter for maintaining an output voltage of the boost converter at a command value of an inter-terminal voltage VH of a smoothing condenser; and a controlling device which is configured to control the output voltage of the boost converter on the basis of the calculated PID controlled variable.
The dynamic system is part of a dynamic apparatus having at least one photovoltaic generator, at least one battery and at least one device for controlling the dynamic apparatus. The method for controlling the dynamic system on the basis of sunlight involves electrically isolating the photovoltaic generator from the battery, reading the short circuit current of the isolated photovoltaic generator, determining a numerical value based on the short circuit current, said numerical value corresponding to the reading of the short circuit current, and comparing the numerical value determined with at least one reference threshold value. When the numerical value determined corresponds to a value range limited by at least one such reference threshold value, the dynamic system is controlled so as to thereon confer a configuration corresponding to the value range.
A brushless motor driving apparatus that rotates and drives a brushless motor, which has a plurality of coils, by switching energization modes corresponding to phases of the brushless motor, sequentially switches the energization modes based on a non-energized phase voltage and a voltage threshold. Also, the brushless motor driving apparatus regulates an upper threshold for energization amount based on the voltage threshold and a change in the non-energized phase voltage at timing of switching the energization mode.
A motor-drive circuit includes a detection circuit to detect a reverse current to flow in a direction from a first sink-side transistor to a second source-side transistor or in a direction from a second sink-side transistor to a first source-side transistor, a disable circuit to disable a detection output of the detection circuit during a predetermined time period from a start of detection of the reverse current performed by the detection circuit, a first inhibit circuit to inhibit synchronous rectification according to a detection output of the detection circuit when the predetermined time period has elapsed from a start of detection of the reverse current performed by the detection circuit, and a second inhibit circuit.
A control apparatus for a three-phase AC motor includes a current sensor and a current estimation section. The current sensor detects current flowing through one phase of the motor. The current estimation section repeats dq transformation and inverse dq transformation in a predetermined cycle. In the dq transformation, a d-axis current estimation value and a q-axis current estimation value in a rotating coordinate system of the AC motor are calculated based on the detected current and a previous current estimation value of another phase of the AC motor. In the inverse dq transformation, a present current estimation value of the other phase to be obtained at a time of angle advance of one period of the cycle is calculated based on smoothed values of the d-axis current estimation value and the q-axis current estimation value.
A portable lighting device, such as a flashlight, with a mechanical power switch and multiple operating modes is provided. The mechanical power switch is disposed in series with the controller for the lighting device and acts as the user interface to the controller to change modes of operation. Because the mechanical power switch is in series with the controller, the portable lighting device does not consume battery power when the mechanical switch is open. A state machine coupled to the controller is polled by the controller each time it is powered up to determine the operational mode of the lighting device.
An LED driving apparatus is provided. The apparatus includes an LED Portion 10, a charging/discharging capacitor 111, a capacitor charging and discharging paths, and a capacitor charging constant current portion 110. The LED driving portion 3 controls a current in the LED portion 10. The capacitor 111 is connected in parallel to the LED portion 10. The charging and discharging paths are connected to the capacitor whereby charging and discharging the capacitor, respectively. The constant current portion 110 is connected on the charging path and controls a charging current so that the capacitor is charged at a constant current. When rectified voltage applied to the LED portion becomes high, the capacitor is charged with the charging current through the charging path. When the voltage becomes low, the capacitor is discharged at a discharging current through the discharging path so that the discharging current is applied to the LED portion.
A ballast circuit adapted for converting an input alternating current (AC) mains power received at input terminals to an output alternating current (AC) to supply a load, e.g. a gas discharge lamp. The output terminals of the ballast connect to the load in parallel with another ballast circuit. The ballast circuit is configured to supply the output AC current to the load in parallel with an AC current output of the other ballast circuit. A synchronization module attached at the output is adapted for synchronizing the output alternating current (AC) of the ballast circuit with the AC current output of the other ballast circuit. The synchronization module is configured to synchronize phase of the output alternating current with phase of the AC current output of the other ballast circuit.
A three-stage power adjustable Light Emitting Diode bulb includes a first resistance and a second resistance which is electrically connected to the first resistance in parallel. The first resistance and the second resistance are connected to a rectifier. Multiple Light Emitting Diode units and a limiting resistance are connected between the positive and negative poles of the rectifier. The Light Emitting Diode units each have multiple Light Emitting Diodes. The electric energy consumption of the Light Emitting Diode bulb is reduced and the life of use of the Light Emitting Diode bulb is prolonged. The resistance value of the first and second resistance can be adjusted to have different luminous powers.
A hybrid plasma reactor includes a reactor body having a plasma discharge space, a gas inlet, and a gas outlet; a hybrid plasma source including an inductive antenna inductively coupled to plasma formed in the plasma discharge space and a primary winding coil transformer coupled to the plasma and wound in a magnetic core; and an alternating switching power supply for supplying plasma generation power to the inductive antenna and the primary winding coil. The hybrid plasma reactor induces a plasma discharge using the inductively coupled plasma source and the transformer coupled plasma source, so that it has a wide operational area from a low pressure area to a high pressure area.
The object of the presently disclosed embodiment is to improve heat dissipation and an overall cooling efficiency to raise a peak oscillation output. To achieve the object, there is provided a coaxial magnetron having the following configuration: Around a cathode, vanes and an anode cylinder form an anode resonant cavity, and a cylindrical side body forms an outer cavity. An input side structure having an input part and an upper structure are joined to both ends of the cylindrical side body. One end of the anode cylinder is joined to the input side structure. A groove (or step) for adjusting the distance between the structures and at the both ends is provided, and the groove is joined to the other end of the anode cylinder.
The organic light emitting display device includes an organic light emitting display panel and a data driver, wherein the organic light emitting display panel includes an active region which includes pixel driving TFTs for embodying an image and organic luminescent elements respectively connected with the pixel driving TFTs to emit light, a GIP region which includes a gate driver formed with a plurality of gate driving TFTs for respectively driving gate lines of the active region, a GND region formed between the GIP region and the active region to be formed with a base voltage line for supplying base voltage to the organic luminescent elements of the active region, and a sealant region formed with a sealant for attaching an upper substrate to a lower substrate, and wherein the GND region includes out-gassing blocking holes.
A spark plug includes an insulator having an axial hole, a metal terminal member having an insert portion and a depression formation zone existing on the insert portion and having depressions, and a metallic shell. The spark plug satisfies the following conditions: (1) the insert portion has a length H of 35 mm or more; (2) the depression formation zone has a length F of 13 mm or more; (3) the insert portion has a smooth surface zone on its outer circumferential surface; (4) the ratio (A/B) between diameter A of a forward end of the insert portion and inside diameter B of the insulator measured at the forward end satisfies the relational expression 0.9≦A/B≦0.98; and (5) Vickers hardness of the insert portion measured at the center of a cross section of the insert portion is 150 Hv or more to 350 Hv or less.
An acoustic wave device includes: a substrate; a functional element that is located on the substrate and excites acoustic waves; a side wall portion that is made of a metal and is located on the substrate so as to surround the functional element; a metal plate that is located above the functional element and the side wall portion, and seals the functional element so that a space is formed above the functional element; and a terminal that is located on the substrate and further out than the side wall portion, and is electrically connected to the functional element.
The electrical energy generating system of the present invention comprises a piece of alignment Buckypaper, an energy generator, a thin deposition and two contacts. The alignment Buckypaper is a thin sheet made from an aggregate of carbon nanotubes. The thin deposition is formed on at least one surface of the alignment Buckypaper by electrolysis to form a semimetal material. A contact is connected with the upper surface of the alignment Buckypaper and the other contact is connected with the lower surface of the alignment Buckypaper. In use, the energy generated by the generator is inputted to the alignment Buckypaper. The energy then ionizes the molecules contained in the alignment Buckypaper. The positive charges move to the upper contact and the negative charges move to the lower contact. Such electrical energy may then be fed to a load connected with the two contacts to do work on the load.
A sensor assembly including one or more capacitive micromachined ultrasonic transducer (CMUT) microarray modules which are provided with a number of individual transducers. The microarray modules are arranged to simulate or orient individual transducers in a hyperbolic paraboloid geometry. The transducers/sensor are arranged in a rectangular or square matrix and are activatable individually, selectively or collectively to emit and received reflected beam signals at a frequency of between about 100 to 170 Hz.
An energy converting device having an eccentric rotor includes a fixed portion and an eccentric rotor. This fixed portion has a central axis, an outer frame, and several fixed coil portions. The eccentric rotor has a bearing, a rotatory shaft, an eccentric arm, an eccentric shaft portion, a supporting plate, an inner annular magnetic portion, and an outer annular magnetic portion. The inner magnetic portion and the outer magnetic portion are concentric and aligned with the eccentric shaft portion. The eccentric shaft portion is offset from the rotary shaft. When the rotary shaft of the eccentric rotor rotates, these fixed coil portions cut through the inner magnetic portion and the outer magnetic portion repeatedly, so magnetic flux passing through the coils alternates accordingly to generate electromotive force. Conversely, it can be used as an electric motor. In addition, it can be integrated with a cycloidal speed reducer to form a motor with speed reduction and torque augmentation capability. The integrated cycloidal motor is compact, does not need a shaft coupler to transmit power from a motor to the reducer, and therefore may operate more smoothly.
A motor has a plurality of permanent magnet pieces aligned is such a manner as to surround an armature core and a magnetic-flux guide ring disposed between the permanent magnet pieces and the armature core for introducing a magnetic flux from the permanent magnet pieces to the armature core. The magnetic-flux guide ring has a confronting portion confronting each of the magnet pieces, an aperture formed in the confronting portion, and a connecting portion connecting adjacent two confronting portions. The aperture is formed in such a manner as to confront a boundary of adjacent magnet pieces.
The present invention provides an auxiliary excitation winding set to be installed at the rotary part of the electric machine (104) composed of a rotary part of the permanent magnetic electric machine or a rotary part of the reluctance electric machine of the switched DC brushless electric machine (1000), and an electric conductive annular brush device (107) is served as an interface for transmitting the electric power, thereby inputting the excitation electric power to the auxiliary excitation winding set; and through controlling the value and the polarity of excitation voltage and current, the magnetic pole of the rotary part of magnet-motive electric machine (104) of the switched DC brushless electric machine (1000) can be performed with the excitation effect of auxiliary excitation or differential excitation or auxiliary compound excitation or differential compound excitation.
It is possible to provide a vibrator configured so as to prevent the leakage of an adhesive out from between a frame and a diaphragm member and a portable information terminal having the vibrator. The vibrator includes: frame 11; diaphragm member 12 vibratably bonded to frame 11; and adhesive 21 used to bond the frame to the diaphragm member. To store adhesive 21, the vibrator further includes gap 22 which is formed between surfaces of frame 11 and diaphragm member 12 facing each other at bonded part 20 where frame 11 is bonded to diaphragm member 12 with adhesive 21, and the gap being used.
At least a rotor fixing portion and a bearing fitting portion are combined to form a hollow rotary shaft. The rotor of a rotary motor portion is fixed on the rotor fixing portion. A thrust radial bearing is fitted on the outer periphery of the bearing fitting portion and a screw nut is fitted to the bearing fitting portion. The rotor fixing portion and the bearing fitting portion are coupled with screw member(s) which are inserted into the hollow rotary shaft from one axial end of the hollow rotary shaft and axially extend inside the bearing fitting portion and the rotor fixing portion. A flange portion of the screw nut is fixed on an abutment portion of the bearing fitting portion in abutment with an end surface of an inner race of the thrust radial bearing that is located on the one axial end side.
A yoke of a motor has a bottom and an open end and accommodates an armature. An end bracket substantially closes the open end of the yoke. A connector portion, which bulges outward of the yoke, and a cutout portion are formed in the circumferential wall of the end bracket. A pair of feed members is provided to extend from the interior of the end bracket to the connector portion through the cutout portion. The end bracket has an accommodation recess for accommodating the noise suppression element at a position corresponding to the cutout portion. Each feed member has an accommodation recess corresponding portion, which corresponds to the accommodation recess, and a cutout portion corresponding portion, which corresponds to the cutout portion. The distance between the accommodation recess corresponding portions of the feed members is greater than the distance between the cutout portion corresponding portions.
An electric machine having a rectifier assembly placed within a rotating shaft of the electric machine to convert the AC output of the electric machine to DC prior to transmission of the electricity from the electric machine.
Embodiments of the subject invention relate to a method and apparatus for providing an electrical energy system. A specific embodiment can incorporate at least one energy harvesting module (H-module), at least one energy storage module (S-module), and at least one power electronic circuit module (C-module). The various modules can be integrated into a standard battery configuration. Specific embodiments pertain to a reconfigurable energy system with modules that can be disconnected and reconnected into different shapes and configurations.
An output converter includes a DCDC conversion section, a secondary side voltage/current monitoring section detecting a power from the DCDC conversion section, a maximum operation point control section determining what voltage is to be set by the DCDC conversion section so that the power detected by the secondary side voltage/current monitoring section is maximum, a DCDC short-circuit switch via which a current from a module bypasses the DCDC conversion section to outside, a primary side voltage/current monitoring section measuring the current from the module, a module short-circuit switch switching between a state where a secondary side cathode and a secondary side anode are short-circuited and a state where they are not short-circuited, the maximum operation point control section causing the DCDC short-circuit switch and the module short-circuit switch to switch.
Electrical power is dynamically managed among one or more power sources and one or more loads. A plurality of monitor nodes is connected to an input terminal connected to each source, and to an output terminal connected to each load. A plurality of electrical power storage cells is connected among the input and output terminals, each cell being capable of storing power from at least one of the sources and being capable of discharging stored power to at least one of the loads. A plurality of controllable switches is connected to the cells. A programmed controller dynamically monitors operating conditions at the monitor nodes during operation of each source and each load, and selectively dynamically controls the switches to interconnect the cells in different circuit topologies in response to the monitored operating conditions.
An ECU is mounted on a vehicle equipped with a converter that can boost a voltage of a power storage device storing electric power for obtaining driving force to output the boosted voltage to a drive load device. The ECU starts boosting at the converter upon satisfaction of at least any of a first condition that a boost request signal Req is received (that is, an output voltage request value of the converter exceeds a voltage Vb of the power storage device) and a second condition that output electric power P of the power storage device is higher than a value obtained by subtracting charge electric power ΔP transiently occurring at the start of boosting from rated electric power Wout (that is, it is predicted that output electric power P will exceed rated electric power Wout in response to the start of boosting).
A system and method for powering an air-drop device is presented. One configuration of the system includes an energy capture device, a generator and an electrical logic unit. The energy capture device converts the movement air passing by the air-drop tail device into kinetic energy. The generator converts that kinetic energy into electrical energy and the electrical logic unit can then be powered by the electrical energy allowing it to perform at least a portion of a mission.
The invention relates to a method for manufacturing a semiconductor substrate, in particular, a semiconductor-on-insulator substrate by providing a donor substrate and a handle substrate, forming a pattern of one or more doped regions typically inside the handle substrate, and then attaching such as by molecular bonding the donor substrate and the handle substrate to obtain a donor-handle compound.
A semiconductor device has a field effect transistor (FET), a mounting member, an output matching circuit board, a relay board, and first and second bonding wire. The FET includes plural cell regions arranged dispersedly and plural drain terminal electrodes connected to each cell region. The output matching circuit board is provided between an output conductive part and the FET, and has a first insulating substrate and a conductive part. A relay board is provided between the output matching circuit board and the FET. The relay board includes a second insulating substrate having a permittivity lower than a permittivity of the second insulating substrate of the output matching circuit board, and which has a relay conductive part on an upper surface of the second insulating substrate.
In a method for forming a packaging structure, a metal pad is formed on a semiconductor substrate, and a first polymer insulating layer is formed over the semiconductor substrate. An opening passing through the first polymer insulating layer is formed to expose a portion of the metal pad. A copper-containing material is deposited in the opening and over the first polymer insulating layer, thereby forming a copper-containing layer having a first thickness and a first width over the first polymer insulating layer. A conductive bump having a second width is formed over the copper-containing layer, in which the second width is smaller than the first width. An exposed portion of the copper-containing layer is etched using the conductive bump as a mask until the exposed portion is reduced to a second thickness, thereby forming a monolithic copper-containing structure.
A die stack comprises a first integrated circuit (IC) die having at least a first device comprising a first source, a first drain and a first gate electrode above a first channel region between the first source and the first drain. A second IC die has at least a second device comprising a second source, a second drain and a second gate electrode above a second channel region between the second source and the second drain. The second gate electrode is connected to the first gate electrode by a path including a first through substrate via (TSV), the second drain connected to the first source by a path including a second TSV.
A substrate with integrated passive devices and method of manufacturing the same are presented. The substrate may include through silicon vias, at least one redistribution layer having a 1st passive device pattern and stacked vias, and an under bump metal layer having a 2nd passive device pattern.
A semiconductor device includes a semiconductor chip, a wiring formed on the semiconductor chip, a passivation film coating the wiring and having an opening for partially exposing the wiring from the passivation film an interposing film formed on a portion of the wiring and facing the opening, and a post bump raisedly formed on the interposing film and with a peripheral edge portion thereof protruding away from the opening more than a peripheral edge of the interposing film in a direction parallel to a surface of the passivation film.
A semiconductor device that improves the heat cycle resistance and power cycle resistance of a power module. An electrode member in which copper posts are formed in a plurality of perforations cut in a support made of a ceramic material is soldered onto a side of an IGBT where an emitter electrode is formed. By soldering the copper posts onto the electrode, heat generated in the IGBT is transferred to the electrode member and is radiated. In addition, even if a material of which the IGBT is made and copper differ in thermal expansivity, stress on a soldered interface is reduced and distortion is reduced. This suppresses the appearance of a crack. As a result, the heat cycle resistance and power cycle resistance of a power module can be improved.
An integrated circuit device is provided. The integrated circuit device includes a die having a first surface and a second surface opposite the first surface. The die has at least one circuit element positioned on its first surface. At least one micro-channel is defined in the second surface of the die. The integrated circuit device includes a cooling substrate attached to the second surface of the die. At least one fluid routing channel is defined in the cooling substrate. The at least one fluid routing channel is connected to the at least one micro-channel defined in the die. Additionally, the cooling substrate has at least one valve positioned within the at least one fluid routing channel. The at least one valve is configured to autonomously regulate a flow rate of a cooling fluid flowing through the at least one fluid routing channel.
A power semiconductor module and a power semiconductor module assembly, which includes a plurality of power semiconductor modules, are disclosed. The power semiconductor module includes an electrically conducting base plate, an electrically conducting top plate, arranged in parallel to the base plate and spaced apart from the base plate, at least one power semiconductor device, which is arranged on the base plate in a space formed between the base plate and the top plate, and at least one presspin, which is arranged in the space formed between the base plate and the top plate to provide contact between the semiconductor device and the top plate. A metallic protection plate can be provided at an inner face of the top plate facing towards the base plate, wherein the material of the protection plate has a melting temperature higher than the melting temperature of the top plate.
An embodiment of this invention uses a massive parallel interconnect fabric (MPIF) at the flipped interface of a core die substrate (having the core logic blocks) and a context die (used for in circuit programming/context/customization of the core die substrate), to produce ASIC-like density and FPGA-like flexibility/programmability, while reducing the time and cost for development and going from prototyping to production, reducing cost per die, reducing or eliminating NRE, and increasing performance. Other embodiments of this invention enable debugging complex SoC through large contact points provided through the MPIF, provide for multi-platform functionality, and enable incorporating FGPA core in ASIC platform through the MPIF. Various examples are also given for different implementations.
The present embodiments provide surface mount devices and/or systems. In some embodiments, the surface mount devices comprise a casing having a recess formed extending at least partially into said casing; and first and second leads each of which is at least partially encased by said casing and each of which has a portion exposed through said recess, wherein at least one of said first and second leads has one or more size reduction features in its said exposed portion that reduces the surface area to provide an increased surface bonding area to said casing around said lead.
An organic light emitting device comprises a first substrate; a thin film transistor layer provided on the first substrate; a light emitting diode layer provided on the thin film transistor layer; and a passivation layer provided on the light emitting diode layer, the passivation layer including a first inorganic insulating film and a second inorganic insulating film, wherein a content of H contained in the first inorganic insulating film is smaller than that of H contained in the second inorganic insulating film.
There is provided a method of processing a surface of a group III nitride crystal, that includes the steps of: polishing a surface of a group III nitride crystal with a polishing slurry containing abrasive grains; and thereafter polishing the surface of the group III nitride crystal with a polishing liquid at least once, and each step of polishing with the polishing liquid employs a basic polishing liquid or an acidic polishing liquid as the polishing liquid. The step of polishing with the basic or acidic polishing liquid allows removal of impurity such as abrasive grains remaining on the surface of the group III nitride crystal after it is polished with the slurry containing the abrasive grains.
A Micro-Electro-Mechanical Systems (MEMS) device includes a first substrate with a first surface and a second surface, the first substrate including a base layer, a moveable beam disposed on the base layer, at least one metal layer, and one or more standoffs disposed on the base layer such that one or more metal layers are situated on the top surface of the one or more standoffs. The MEMS device further includes a second substrate including one or more metal layers bonded to the one or more standoffs resulting in an electrical connection between at least a portion of the one or more metal layers of the second substrate and one or more of the at least one electrode on the bottom surface and the at least one electrode on the top surface.
Some novel features pertain to a first example provides a semiconductor device that includes a printed circuit board (PCB), asset of solder balls and a die. The PCB includes a first metal layer. The set of solder balls is coupled to the PCB. The die is coupled to the PCB through the set of solder balls. The die includes a second metal layer and a third metal layer. The first metal layer of the PCB, the set of solder balls, the second and third metal layers of the die are configured to operate as an inductor in the semiconductor device. In some implementations, the die further includes a passivation layer. The passivation layer is positioned between the second metal layer and the third metal layer. In some implementations, the second metal layer is positioned between the passivation layer and the set of solder balls.
Pitch multiplied and non-pitch multiplied features of an integrated circuit, e.g., features in the array, interface and periphery areas of the integrated circuit, are formed by processing a substrate through a mask. A photoresist layer is patterned to simultaneously define mask elements in the array, interface and periphery areas. The pattern is transferred to an amorphous carbon layer. Spacers are formed on the sidewalls of the patterned amorphous carbon layer. Protective material is deposited and patterned to expose mask elements in the array region and in parts of the interface or periphery areas. Exposed amorphous carbon is removed, leaving free-standing spacers in the array region. The protective material is removed, leaving a pattern of pitch multiplied spacers in the array region and non-pitch multiplied mask elements in the interface and periphery areas. The pattern is transferred to a hard mask layer, through which the substrate is etched.
A technology for a vertical semiconductor device having a RESURF structure, which is capable of preventing the drop of the withstand voltage when the adhesion of external electric charges occurs is provided. The vertical semiconductor device disclosed in the present specification has a cell region and a non-cell region disposed outside the cell region. This vertical semiconductor device has a diffusion layer disposed in at least part of the non-cell region. When the vertical semiconductor device is viewed in a plane, the diffusion layer has an impurity surface density higher than that satisfying a RESURF condition at an end part close to the cell region, and an impurity surface density lower than that satisfying the RESURF condition at an end part far from the cell region. When the vertical semiconductor device is viewed in a plane, a region in the diffusion layer that has the impurity surface density higher than that satisfying the RESURF condition has a greater mean gradient of the impurity surface density than a region in the diffusion layer that has the impurity surface density lower than that satisfying the RESURF condition.
A semiconductor device includes a semiconductor layer and a Schottky electrode, a Schottky junction being formed between the semiconductor layer and the Schottky electrode. The Schottky electrode includes a metal part containing a metal, a Schottky junction being formed between the semiconductor layer and the metal part; and a nitride part around the metal part, the nitride part containing a nitride of the metal, and a Schottky junction being formed between the semiconductor layer and the nitride part.
According to one embodiment, a semiconductor memory device comprises a cell transistor includes a first gate electrode buried in a semiconductor substrate and a first diffusion layer and a second diffusion layer formed to sandwich the first gate electrode, a first lower electrode formed on the first diffusion layer, a magnetoresistive element formed on the first lower electrode to store data according to a change in a magnetization state and connected to a bit line located above, a second lower electrode formed on the second diffusion layer, and a first contact formed on the second lower electrode and connected to a source line located above. A contact area between the second lower electrode and the second diffusion layer is larger than a contact area between the first contact and the second lower electrode.
A physical quantity detection device includes a glass substrate, a substrate including a physical quantity detection part and bonded to a first surface of the glass substrate with a hermetically sealed space being formed inside the substrate, and a function membrane formed on a second surface of the glass substrate opposite to the first surface. The function membrane prevents the second surface of the glass substrate from coming into contact with moisture in the atmosphere.
Disclosed herein is a micro electro mechanical systems (MEMS) device including: a mass body; a first fixed part provided at an outer side of the mass body; and a first flexible part having one end connected to a distal end of the mass body and the other end connected to the first fixed part, wherein the mass body is rotatably connected to the first flexible part.
A semiconductor device includes a fin-shaped silicon layer on a silicon substrate and a first insulating film around the fin-shaped silicon layer. A pillar-shaped silicon layer resides on the fin-shaped silicon layer. A gate electrode and gate insulating film surround the pillar-shaped silicon layer and a gate line is connected to the gate electrode and extends in a direction orthogonally intersecting the fin-shaped silicon layer. A first diffusion layer resides in an upper portion of the pillar-shaped silicon layer and a second diffusion layer resides in an upper portion of the fin-shaped silicon layer and a lower portion of the pillar-shaped silicon layer. A first silicide resides in an upper portion of the first diffusion layer and a second silicide resides in an upper portion of the second diffusion layer. A contact and metal wire are on the second silicide, and a metal wire is on the first contact.
A method of fabricating an electronic device includes the following steps. At least one first set and at least one second set of nanowires and pads are etched in an SOI layer of an SOI wafer. A first gate stack is formed that surrounds at least a portion of each of the first set of nanowires that serves as a channel region of a capacitor device. A second gate stack is formed that surrounds at least a portion of each of the second set of nanowires that serves as a channel region of a FET device. Source and drain regions of the FET device are selectively doped. A first silicide is formed on the source and drain regions of the capacitor device that extends at least to an edge of the first gate stack. A second silicide is formed on the source and drain regions of the FET device.
An aspect of the present embodiment, there is provided a semiconductor device includes a high-voltage element, the high-voltage element including a substrate, a first semiconductor region with a first conductive type on the substrate, an insulating isolation film on the substrate, a second semiconductor region with a second conductive type, the second semiconductor region being provided between the first semiconductor region and the insulating isolation film, a drain region with the second conductive type provided on a surface of the second semiconductor region, an impurity concentration of the drain region being higher than an impurity concentration of the second semiconductor region, a source region with the second conductive type provided on a surface of the first semiconductor, the source region being separated from the drain region, a floating drain region with the second conductive type provided on the surface of the first semiconductor region between the second semiconductor region and the source region, a first gate electrode above the first semiconductor region between the drain region and the floating drain region, a second gate electrode above the first semiconductor region between the source region and the floating drain region, a gate insulator provided between the first gate electrode and the surface of the first semiconductor region, the first gate electrode and the surface of the second semiconductor region, and the second gate electrode and the surface of the first semiconductor region, a portion of the second semiconductor region being placed under the first gate electrode through the gate insulator to be overlapped with the first gate electrode, a drain electrode on the drain region, and a source electrode on the source region.
An integrated circuit includes a high-voltage well having a first doping type, a first doped region and a second doped region embedded in the high-voltage well, the first and second doped regions having a second doping type and spaced apart by a channel in the high-voltage well, source/drain regions formed in the first doped region and in the second doped region, each of the source/drain regions having the second doping type and more heavily doped than the first and second doped regions, first isolation regions spaced apart from each of the source/drain regions, and resistance protection oxide forming a ring surrounding each of the source/drain regions.
A semiconductor device includes a logic circuit and an active element circuit. The logic circuit is provided with semiconductor elements formed in a semiconductor substrate. The active element circuit is provided with transistors formed using semiconductor layers formed over a diffusion insulating film formed above a semiconductor substrate. The active element circuit is controlled by the logic circuit.
A semiconductor device having a p base region and an n+ emitter region that come into contact with an emitter electrode and are selectively provided in a surface layer of an n− drift layer. A gate electrode is provided on a portion of the front surface of the n− drift layer which is interposed between the n+ emitter regions, with a gate insulating film interposed therebetween. In some exemplary embodiments, an n+ buffer layer and a p collector layer which have a higher impurity concentration than the n− drift layer are sequentially provided on a surface of the n− drift layer opposite to the front surface on which the n+ emitter region is provided. The impurity concentration of the n+ buffer layer is equal to or greater than 7×1016 cm−3 and equal to or less than 7×1017 cm−3. Accordingly, it is possible to obtain high field decay resistance.
A device includes, within a layer of silicon on insulator, a central semiconductor zone including a central region having a first type of conductivity, two intermediate regions having a second type of conductivity opposite to that of the first one, respectively disposed on either side of and in contact with the central region in order to form two PN junctions, two semiconductor end zones respectively disposed on either side of the central zone, each end zone comprising two end regions of opposite types of conductivity, in contact with the adjacent intermediate region, the two end regions of each end zone being mutually connected electrically in order to form the two terminals of the device.
Disclosed is a light emitting device and a method of manufacturing the same. The light emitting device includes a body, a first electrode installed in the body and a second electrode separated from the first electrode, a light emitting chip formed on one of the first and second electrodes, and electrically connected to the first and second electrodes, and a protective cap projecting between the first and second electrodes.
An object is to provide a light-emitting module in which a light-emitting element suffering a short-circuit failure does not cause wasteful electric power consumption. Another object is to provide a light-emitting panel in which a light-emitting element suffering a short-circuit failure does not allow the reliability of an adjacent light-emitting element to lower. Focusing on heat generated by a light-emitting element suffering a short-circuit failure, provided is a structure in which electric power is supplied to a light-emitting element through a positive temperature coefficient thermistor (PTC thermistor) thermally coupled with the light-emitting element.
An LED component includes, according to a first embodiment, a monolithic substrate, an array of LED chips disposed on a surface of the substrate, and an optical lens overlying the LED chips and having a lens base attached to the substrate, where the LED chips are positioned to provide a peak emission shifted from a perpendicular centerline of the lens base. The LED component includes, according to a second embodiment, a monolithic substrate, an array of LED chips disposed on a surface of the substrate, and an array of optical lenses, each optical lens overlying at least one of the LED chips and having a lens base attached to the substrate, where at least one of the LED chips is positioned to provide a peak emission shifted from a perpendicular centerline of the respective lens base.
A multi-chip light emitting device (LED) uses a low-cost carrier structure that facilitates the use of substrates that are optimized to support the devices that require a substrate. Depending upon the type of LED elements used, some of the LED elements may be mounted on the carrier structure, rather than on the more expensive ceramic substrate. In like manner, other devices, such as sensors and control elements, may be mounted on the carrier structure as well. Because the carrier and substrate structures are formed independent of the encapsulation and other after-formation processes, these structures can be tested prior to encapsulation, thereby avoiding the cost of these processes being applied to inoperative structures.
According to one embodiment, a semiconductor device includes a substrate, a first semiconductor region, a second semiconductor region, a first electrode, a first electrode and a conducting section. The substrate includes a conductive region and has a first surface. The first semiconductor region is provided on the first surface side of the substrate and includes AlXGa1-XN (0≦X≦1). The second semiconductor region is provided on a side opposite to the substrate of the first semiconductor region and includes AlYGa1-YN (0≦Y≦1, X≦Y). The first electrode is provided on a side opposite to the first semiconductor region of the second semiconductor region and ohmically connects to the second semiconductor region. The conducting section electrically connects between the first electrode and the conductive region.
A semiconductor device includes a GaN FET with an overvoltage clamping component electrically coupled to a drain node of the GaN FET and coupled in series to a voltage dropping component. The voltage dropping component is electrically coupled to a terminal which provides an off-state bias for the GaN FET. The overvoltage clamping component conducts insignificant current when a voltage at the drain node of the GaN FET is less than the breakdown voltage of the GaN FET and conducts significant current when the voltage rises above a safe voltage limit. The voltage dropping component is configured to provide a voltage drop which increases as current from the overvoltage clamping component increases. The semiconductor device is configured to turn on the GaN FET when the voltage drop across the voltage dropping component reaches a threshold value.
An object of the present invention is to provide an electrooptical device having high operation performance and reliability, and a method of manufacturing the electrooptical device.Lov region 207 is disposed in n-channel TFT 302 that comprises a driver circuit, and a TFT structure which is resistant to hot carriers is realized. Loff regions 217 to 220 are disposed in n-channel TFT 304 that comprises a pixel section, and a TFT structure of low off current is realized. An input-output signal wiring 305 and gate wiring 306 are formed by laminating a first wiring and a second wiring having lower resistivity than the first wiring, and wiring resistivity is steeply reduced.
A thin film transistor (TFT) using an oxide semiconductor as an active layer, a method of manufacturing the TFT, and a flat panel display device having the TFT include a gate electrode formed on a substrate; an active layer made of an oxide semiconductor and insulated from the gate electrode by a gate insulating layer; source and drain electrodes coupled to the active layer; and an interfacial stability layer formed on one or both surfaces of the active layer. In the TFT, the interfacial stability layer is formed of an oxide having a band gap of 3.0 to 8.0 eV. Since the interfacial stability layer has the same characteristic as a gate insulating layer and a passivation layer, chemically high interface stability is maintained. Since the interfacial stability layer has a band gap equal to or greater than that of the active layer, charge trapping is physically prevented.
In a sophisticated semiconductor device, FINFET elements may be provided with individually accessible semiconductor fins which may be connected to a controllable interconnect structure for appropriately adjusting the transistor configuration, for instance with respect to current drive capability, replacing defective semiconductor fins and the like. Consequently, different transistor configurations may be obtained on the basis of a standard transistor cell architecture, which may result in increased production yield of highly complex manufacturing strategies in forming non-planar transistor devices.
A thin film transistor includes a semiconductor layer disposed on a base substrate and including an oxide semiconductor material, a source electrode and a drain electrode, which respectively extend from opposing ends of the semiconductor layer, a plurality of low carrier concentration areas respectively disposed between the source electrode and the semiconductor layer and between the drain electrode and the semiconductor layer, a gate insulating layer disposed on the semiconductor layer, and a gate electrode disposed on the gate insulating layer.
Organic EL device comprising: anode and cathode disposed to face each other with gap therebetween; functional layer that contains organic material and is disposed between the anode and the cathode; and hole injection layer that has function to inject holes into the functional layer and is disposed between the anode and the functional layer, wherein the hole injection layer is mixture layer containing first oxide and second oxide. The first oxide is p-type metal oxide, the composition of the second oxide contains element that is thermally stable in both first state where the element has the maximum valence and second state where the element has valence smaller than the maximum valence, the element being more thermally stable in the second state than in the first state. The element contained in the composition of the second oxide in the hole injection layer is in the first state.
A method and structure for stabilizing an array of micro devices is disclosed. A stabilization layer includes an array of stabilization cavities and array of stabilization posts. Each stabilization cavity includes sidewalls surrounding a stabilization post. The array of micro devices is on the array of stabilization posts. Each micro device in the array of micro devices includes a bottom surface that is wider than a corresponding stabilization post directly underneath the bottom surface.
A method for fabricating a semiconductor device includes forming an impurity layer over a first conductive layer; forming a first metal oxide layer over the impurity layer, wherein the first metal oxide layer includes oxygen at a lower ratio than a stoichiometric ratio; diffusing an impurity from the impurity layer into the first metal oxide layer to form a first doped metal oxide layer; forming a second metal oxide layer over the first doped metal oxide layer; and forming a second conductive layer over the second metal oxide layer.
The present invention is directed to a mobile radiation system that comprises a mobile radiation device coupled to a control unit; a radiation blocker having an adaptor opening for receiving said mobile radiation device when said mobile radiation device is in a seated position on said radiation blocker; and a mobile carrier comprising a first compartment for housing said radiation blocker, a second compartment for housing said control unit, and one or more carrier motion devices. The adaptor opening can dimensionally fit the mobile radiation device to block radiations from the mobile radiation device when said mobile radiation device is in the seated position. The mobile radiation device can produce radiation having peak radiation wavelength in a range of from 250 nm to 450 nm and can have a peak irradiation power in a range of from 0.5 W/cm2 to 10 W/cm2.
A radiation image imaging apparatus includes: a sensor board in which a plurality of photoelectric conversion elements are arranged two-dimensionally; and a scintillator which converts an incident radiation into light and irradiates the light onto the photoelectric conversion elements, and a protection layer having an anti-static function is provided between the sensor board and the scintillator, and an anti-static layer having conductivity or an anti-static function is provided on a surface of the sensor board, the surface being opposite with a side facing the scintillator.
A human body sensing device comprises: an infrared sensor which detects a human body; a rotatable group of lenses having a plurality of lenses arranged around the sensor, the lenses being configured to: generate unit sensing zones defined by a sensing distance extending radially outwardly from the group and a small width extending in a rotation direction of the group; and form a plurality of alternating layers of a regional sensing zone including one or more than one of the unit sensing zones and a non-sensing zone not including any of the unit sensing zones, in a rotation direction of the group; a rotary drive which rotates the group; a rotation position sensor which detects a rotation position of the group; and a recognizer which recognizes the location and/or movement of a human body based on the output level indicated by the infrared sensor and the rotation position.
An ion guiding device is disclosed comprising a first ion guide which is conjoined with a second ion guide. Ions are urged across a radial pseudo-potential barrier which separates the two guiding regions by a DC potential gradient. Ions may be transferred from an ion guide which has a relatively large cross-sectional profile to an ion guide which has a relatively small cross-sectional profile in order to improve the subsequent ion confinement of the ions.
Systems and methods are provided for determining a property, e.g., density, of a geological formation based on Einstein's theory of gravitation. A gravitational potential difference is determined between two positions of the geological formation by measuring a frequency shift of a radiation travelling from a source to an absorber of a differential gravimeter. The gravitational potential difference determined can be converted to a density of the geological formation, e.g., based on a concentric spherical shell model. The systems can be a part of a downhole tool.
An optical communication module includes a lens unit and an optical-electrical converter. The optical-electrical converter includes a circuit board and the lens unit is fixed on the circuit board. The lens unit has an extension portion, and the extension portion extends outwards from the lens unit and is parallel to the circuit board. Glue is located between the extension portion and the circuit board to secure the lens unit on the circuit board.
In an imaging device, one end of a capacitive element is connected to a second input terminal to which a reference signal Ramp is applied, and the other end of the capacitive element is connected to a voltage source during a reset operation and to a voltage source after the reset operation through a switching element. As a result, the voltage of the second input terminal is changed such that a voltage difference between the first input terminal and the second input terminal becomes a voltage guaranteeing a comparison operation after the reset operation.
In a method and device for machining material, an unfocused beam of laser radiation is focused and directed at the material surface, creating an interface of laser radiation and material to be machined. The beam waist, which results from the focusing the laser radiation, is held in the region of the interface of laser radiation and material. The spacing of the beam waist from the upper or lower side of the interface in the axial direction corresponds at most to triple the value of the penetration depth of the interface into the material. The focusing is effected such that components of the laser radiation are made divergent not just in the propagation direction downstream of the beam waist but also in the beam waist itself and/or also in the propagation direction upstream of the beam waist.
A laser processing device (100) comprises a laser light source (101) for emitting a laser light (L) and a laser light source controller (102) for controlling the pulse width of the laser light (L) and irradiates an object to be processed (1) with the laser light (L) while locating a converging point (P) within the object (1), so as to form a modified region along a line to cut (5) of the object (1) and generate a fracture extending in a thickness direction of the object (1) from the modified region as the modified region is formed. In the laser processing device (100), the laser light source controller (102) changes the pulse width of the laser light (L) according to a data table in which the fracture length, the thickness of the object (1), and the pulse width of the laser light (L) are associated with each other. That is, the pulse width is changed according to the fracture length generated from the modified region. Therefore, the laser processing device (100) can generate a fracture having a desirable length from the modified region.
Disclosed is a method for connecting a core wire of a wire rod covered with an insulating coating and pulled out from a coil component with a substrate by irradiating a laser beam, the method comprising the steps of: (a) forming a bond part between the wire rod and the substrate, the bond part being made of a material having a high optical absorptance for laser beam; and (b) irradiating a laser beam on an area to be connected under a state that at least one of the wire rod and the substrate is being pulled toward the other.
A welding method for welding workpieces made of highly heat-resistant superalloys is provided. The method includes generating a heat input zone on the workpiece surface by means of a heat source, feeding welding filler material into the heat input zone by means of a feeding device, and generating a relative motion between the heat source and the feeding device on one hand and the workpiece surface on the other hand by means of a conveying device. Furthermore, according to the welding method, the mass feed rate is ≦350 mg/min.
An optical robotic sorting method and apparatus for identifying and sorting a product is provided. In the preferred embodiment, the method comprises the steps of illuminating the product with a light source, imaging the product using at least one imaging device, analyzing the image, and activating a robotic sorter to sort the product.
A multi-directional tilt switch includes a housing inner surface defining a chamber, a housing outer surface opposite to the housing inner surface, a plurality of slots extending through the housing inner and outer surfaces, and a plurality of conductive terminals each including an insert portion inserted in a corresponding slot, a contact portion extending into the chamber, and a first connecting surface exposed from the housing outer surface. A conductive body is accommodated movably in the chamber between a first position, where the conductive body bridges two contact portions, and a second position, where the conductive body does not bridge any two contact portions.
The present invention provides a transparent conductive substrate comprising: a transparent substrate, and a conductive pattern provided on the transparent substrate, wherein the conductive pattern comprises line breakage portions performing electric breakage, and a pattern of a broken line formed when the line breakage portions are connected comprises an irregular pattern shape. The present invention can minimize a moiré phenomenon and a diffraction phenomenon by external light by performing line breakage of a regular or irregular conductive pattern by using the irregular pattern.
The present invention relates to circuit boards and, more specifically, circuit boards with vias (i.e. via holes) exhibiting reduced via capacitance. In one embodiment, the present invention provides a circuit board comprising a first electrically conductive trace, a second electrically conductive trace, a via hole including electrically conductive material thereon, and a coupling element that electrically connects the first trace to the second trace. The coupling element comprises a segment of the via hole that bridges the first trace and the second trace, wherein the via hole segment is a remainder of the via hole after removal of a portion of the via hole.
Disclosed herein is a circuit board including: a core layer including a via hole; a metal film covering an inner wall of the via hole; a circuit pattern connected to the metal film on the core layer; and a plug surrounded by the metal film in the via hole and having a thickness thinner than a thickness of the core layer.
A cover assembly for a floor box includes a base with a central opening and a cover pivotally connected to the base by a hinge member. The hinge member has a hinge body with a first end pivotally connected to the base for pivoting with respect to the base and second end pivotally connected to the cover for pivoting with respect to the cover. A tab extends from the second end of the hinge body to contact a bottom surface of the cover to limit pivoting movement of the cover with respect to the hinge body. A slide surface is provided on the base that contacts an end of the cover during pivoting movement of the cover to prevent wear on a gasket with the opening of the base.
[Problem] To provide a photovoltaic device capable of generating power whether day or night, without affecting the appearance of a structure or reducing lighting or other functions, and able to inhibit rises in room temperature by converting thermal radiation into electrical energy.[Means to Solve Problems] Provide a photoelectric conversion element 3 with a photovoltaic device 1 on structural members 2a-2d facing the outside of a house or other structure. Power generated by the photoelectric conversion element 3 is extracted via a power extraction unit 4. The power conversion element 3 includes a semiconductor layer 11, conductive layer 20, a metal nanostructure 30 having multiple periodic structures 33, a first electrode 41 and a second electrode 42. The first and second electrodes 41, 42 are separated in the direction of the surface of the photoelectric conversion element 1 with the terminals 71, 81 of the power extraction unit 4 respectively connected.
A keyboard musical instrument, including: a key; a board; a first member formed of a material different from a material of the board; a first acoustic transducer configured to vibrate the board in accordance with a drive signal supplied thereto; and a second acoustic transducer configured to vibrate the first member in accordance with a drive signal supplied thereto.
A novel maize variety designated PH18PF and seed, plants and plant parts thereof. Methods for producing a maize plant that comprise crossing maize variety PH18PF with another maize plant. Methods for producing a maize plant containing in its genetic material one or more traits introgressed into PH18PF through backcross conversion and/or transformation, and to the maize seed, plant and plant part produced thereby. Hybrid maize seed, plant or plant part produced by crossing the variety PH18PF or a locus conversion of PH18PF with another maize variety.
A novel maize variety designated X08D387 and seed, plants and plant parts thereof, produced by crossing Pioneer Hi-Bred International, Inc. proprietary inbred maize varieties. Methods for producing a maize plant that comprises crossing hybrid maize variety X08D387 with another maize plant. Methods for producing a maize plant containing in its genetic material one or more traits introgressed into X08D387 through backcross conversion and/or transformation, and to the maize seed, plant and plant part produced thereby. This invention relates to the maize variety X08D387, the seed, the plant produced from the seed, and variants, mutants, and minor modifications of maize variety X08D387. This invention further relates to methods for producing maize varieties derived from maize variety X08D387.
A novel soybean variety, designated XR31L13 is provided. Also provided are the seeds of soybean variety XR31L13, cells from soybean variety XR31L13, plants of soybean XR31L13, and plant parts of soybean variety XR31L13. Methods provided include producing a soybean plant by crossing soybean variety XR31L13 with another soybean plant, methods for introgressing a transgenic trait, a mutant trait, and/or a native trait into soybean variety XR31L13, methods for producing other soybean varieties or plant parts derived from soybean variety XR31L13, and methods of characterizing soybean variety XR31L13. Soybean seed, cells, plants, germplasm, breeding lines, varieties, and plant parts produced by these methods and/or derived from soybean variety XR31L13 are further provided.
The cotton variety ST 4145LLB2 is disclosed. The invention relates to seeds, plants, plant cells, plant tissue, harvested products and cotton lint as well as to hybrid cotton plants and seeds obtained by repeatedly crossing plants of variety ST 4145LLB2 with other plants. The invention also relates to plants and varieties produced by the method of essential derivation from plants of ST 4145LLB2 and to plants of ST 4145LLB2 reproduced by vegetative methods, including but not limited to tissue culture of regenerable cells or tissue from ST 4145LLB2.
Novel herbicide-resistant sunflower plants designated as MUT31 and herbicide-resistant descendents thereof are provided. The MUT31 sunflower plants and the herbicide-resistant descendents thereof comprise increased resistance to at least one imidazolinone herbicide, when compared to wild-type sunflower plants. Methods for controlling weeds in the vicinity of these herbicide-resistant sunflower plants and methods for increasing the herbicide-resistance of a sunflower plant are also provided.
The invention relates to polynucleotides encoding a modified HaHB4 transcription factor and polynucleotides encoding functionally active fragments and variants of a modified HaHB4 transcription factor as well as vectors and host cells containing these polynucleotides and the polypeptides encoded by these polynucleotides. The invention also encompasses transgenic host cells, plants, seed, pollen, and plant parts containing the polypeptides and/or polynucleotides of the invention. The invention further encompasses methods of producing transgenic host cells, plants, seed, pollen, and plant parts and the processed plant products produced from these transgenic hosts.
A wound dressing including a hydrophilic layer and a hydrophobic layer is described. The hydrophilic layer absorbs exudate from a wound and the hydrophobic layer absorbs the exudate from the hydrophilic layer and traps the exudate. Because the hydrophilic layer is used adjacent to the wound, the exudate is readily absorbed thereby reducing the risk of maceration and infection of the wound tissue by the exudate. The hydrophobic layer receives the absorbed exudate from the hydrophilic layer and traps the exudate through an interaction that in turn prevents lateral diffusion of the exudate through the bandage to healthy portions of the skin. The hydrophilic and hydrophobic layers are fabricated from polymer fibers that can be spun to include components that facilitate wound healing, such as poly(hexamethylene biguanide) and/or hyaluronic acid.
A process for reforming a hydrocarbon stream is presented. The process involves splitting a naphtha feedstream to at least two feedstreams and partially processing each feedstream in separate reactors. The processing includes passing the light stream to a combination hydrogenation/dehydrogenation reactor. The process reduces the energy by reducing the endothermic properties of intermediate reformed process streams.
This specification discloses an operational continuous process to convert lignin as found in ligno-cellulosic biomass before or after converting at least some of the carbohydrates. The continuous process has been demonstrated to create a slurry comprised of lignin, raise the slurry comprised of lignin to ultra-high pressure, deoxygenate the lignin in a lignin conversion reactor over a catalyst which is not a fixed bed without producing char. The conversion products of the carbohydrates or lignin can be further processed into polyester intermediates for use in polyester preforms and bottles.
A hydrocarbon conversion process comprises contacting a renewable feedstock under hydroprocessing conditions with a bulk catalyst to form oleochemicals such as fatty alcohols, esters, and normal paraffins. Advantageously, the reaction conditions can be selected to directly convert the renewable feedstock to the desired product(s).
The present invention relates to a method for the hydroxylation of phenols and phenol ethers by means of hydrogen peroxide. The invention specifically relates to a method for the hydroxylation of phenol by means of the hydrogen peroxide. The method of the invention for the hydroxylation of a phenol or phenol ether by means of reacting said phenol or phenol ether with the hydrogen peroxide in the presence of an acid catalyst is characterized in that it includes mixing a phenol or phenol ether with a hydrogen peroxide solution in a mixing device under conditions enabling the conversion rate of the hydrogen peroxide to be minimized, and in that said reaction mixture is then placed in a piston flow reactor where the reaction leading to the production of the hydroxylated material takes place, the acid catalyst being fed into the mixing device and/or into the piston flow reactor.
A method for producing a phenylphosphonic acid metal salt composition, including reacting a phenylphosphonic acid compound (a) with a metal salt, metal oxide or metal hydroxide (b) that is present in an amount beyond the equivalent, the phenylphosphonic acid metal salt composition containing phenylphosphonic acid metal salt, and a surplus amount of the metal salt, the metal oxide or the surplus metal hydroxide (b). A crystal nucleating agent comprises the phenylphosphonic acid metal salt composition produced by the method.
A process for conversion of aliphatic bicyclic amines to aliphatic diamines including contacting one or more bicyclic amines selected from the group consisting of 3-azabicyclo[3.3.1]nonane and azabicyclo[3.3.1]non-2-ene with ammonia and hydrogen, and alcohols in the presence of heterogeneous metal based catalyst systems, a metal selected from the group consisting of Co, Ni, Ru, Fe, Cu, Re, Pd, and their oxides at a temperature from 140° C. to 200° C. and a pressure from 1540 to 1735 psig for at least one hour reactor systems; forming a product mixture comprising aliphatic diamine(s), bicyclic amine(s), ammonia, hydrogen, and alcohol(s); removing said product mixture from the reactor system; removing at least some of the ammonia, hydrogen, water, alcohols, bicyclic amines from said product mixture; thereby separating the aliphatic diamines from said product mixture.
Processes are disclosed for the conversion of 1,6-hexanediol to adipic acid employing a chemocatalytic reaction in which 1,6-hexanediol is reacted with oxygen in the presence of particular heterogeneous catalysts including at least one of platinum or gold. The metals are preferably provided on a support selected from the group of titania, stabilized titania, zirconia, stabilized zirconia, silica or mixtures thereof, most preferably zirconia stabilized with tungsten. The reaction with oxygen is carried out at a temperature from about 100° C. to about 300° C. and at a partial pressure of oxygen from about 50 psig to about 2000 psig.
The present invention provides aryl ketone compounds and compositions containing them which facilitate the delivery of active agents. The aryl ketone compounds have the formula or a salt thereof, where n=1 to 9, and R1 to R5 are independently hydrogen, C1 to C4 alkyl, C1 to C4 alkoxy, C2 to C4 alkenyl, halogen, hydroxyl, —NH—C(O)—CH3, or —O—C6H5.
The esterfication of hypophosphorous acid is followed by reaction with another molecule of alcohol under the action of a nickel catalyst to provide a green method for the preparation of H-phosphonate diesters. This method avoids the need for any stoichiometric chlorine unlike those based on phosphorous trichloride.
Substrates, surfaces, assemblies, kits, compositions, and methods are provided for forming touch screens and other appliance surfaces exhibiting good hydrophobicity, oleophobicity, and abrasion resistance. Methods are provided for increasing a population density of hydroxyl groups on a touch surface of a touch screen substrate without affecting the compressive strength of the back surface. The treated touch surface of the substrate can then be coated with a coating that includes an organo-metallic and/or silane, for example, a fluorosilane such as a perfluoropolyether alkoxysilane. A substrate can retain its compressive resistance to breakage by impact applied to the touch surface while minimizing any decrease in compressive strength against impact against the touch surface. Examples of such substrates include touch screens for mobile and desktop electronic devices, components of 3D display devices, and components for electrowetting display devices.
A description is given of N-(1,2,5-oxadiazol-3-yl)pyridinecarboxamides of the general formula (I) as herbicides. R in this formula (I) stands for radicals such as hydrogen, organic radicals, and other radicals such as halogen. W stands for a substituted pyridyl radical.
This invention relates to novel compounds which are inhibitors of the Rearranged during Transfection (RET) kinase, to pharmaceutical compositions containing them, to processes for their preparation, and to their use in therapy, alone or in combination, for the normalization of gastrointestinal sensitivity, motility and/or secretion and/or abdominal disorders or diseases and/or treatment related to diseases related to RET dysfunction or where modulation of RET activity may have therapeutic benefit including but not limited to all classifications of irritable bowel syndrome (IBS) including diarrhea-predominant, constipation-predominant or alternating stool pattern, functional bloating, functional constipation, functional diarrhea, unspecified functional bowel disorder, functional abdominal pain syndrome, chronic idiopathic constipation, functional esophageal disorders, functional gastroduodenal disorders, functional anorectal pain, inflammatory bowel disease, proliferative diseases such as non-small cell lung cancer, hepatocellular carcinoma, colorectal cancer, medullary thyroid cancer, follicular thyroid cancer, anaplastic thyroid cancer, papillary thyroid cancer, brain tumors, peritoneal cavity cancer, solid tumors, other lung cancer, head and neck cancer, gliomas, neuroblastomas, Von Hippel-Lindau Syndrome and kidney tumors, breast cancer, fallopian tube cancer, ovarian cancer, transitional cell cancer, prostate cancer, cancer of the esophagus and gastroesophageal junction, biliary cancer, adenocarcinoma, and any malignancy with increased RET kinase activity.
A process for preparing the compound of the following formula (E): wherein Bn represents a benzyl group, and tBu represents a tert-butyl group, the process including: (a) subjecting the following compound (B) to trifluoroacetylation, wherein tBu represents a tert-butyl group to produce the following compound (C): wherein tBu represents a tert-butyl group, and TFA represents a trifluoroacetyl group; (b) reacting the compound (C) with benzyloxyamine in the presence of a hydroxyl group activating agent to produce the following compound (D): wherein Bn represents a benzyl group, tBu represents a tert-butyl group, and TFA represents a trifluoroacetyl group; and (c) subjecting the compound (D) to detrifluoroacetylation.
Tracers for imaging distribution of reactive oxygen species (ROS) are disclosed. The tracers include radiolabeled dihydroethidine (DHE) analogues. Further disclosed are uses of the compounds, including methods of imaging tissue distribution of ROS in vivo by positron emission tomography (PET). Methods of synthesizing the compounds are also disclosed.
The present invention relates to processes and intermediates for preparing compounds useful as inhibitors of ATR kinase, such as aminopyrazine-isoxazole derivatives and related molecules. The present invention also relates to compounds useful as inhibitors of ATR protein kinase. The invention relates to pharmaceutically acceptable compositions comprising the compounds of this invention; methods of treating of various diseases, disorders, and conditions using the compounds of this invention; processes for preparing the compounds of this invention; intermediates for the preparation of the compounds of this invention; and solid forms of the compounds of this invention.The compounds of this invention have formula I or II: wherein the variables are as defined herein.
Disclosed herein are methods and reagents for determining the responsiveness of cancer to an epidermal growth factor receptor (EGFR) targeting treatment. The detection of these mutations will allow for the administration of gefitinib, erlotinib and other tyrosine kinase inhibitors to those patients most likely to respond to the drug.
The present invention relates functional ligands to target molecules, particularly to functional nucleic acids and modifications thereof, and to methods for simultaneously generating, for example, numerous different functional biomolecules, particularly to methods for generating numerous different functional nucleic acids against multiple target molecules simultaneously. The present invention further relates to functional ligands which bind with affinity to target molecules. The present invention further relates to methods for generating, for example, functional biomolecules, particularly to functional nucleic acids, that bind with functional activity to another biomolecule, such as a receptor molecule. More than one or multiple targets as used herein may generally include different types of targets, and/or may also include a multitude of a singular type of targets at different conditions, such as, for example, temperature, pH, chemical environment, and/or any other appropriate conditions.
To provide a diagnostic and therapeutic medicament, a bombesin analog peptide antagonist conjugate is provided which has general Formula (I), wherein A is a metal chelator comprising at least one radionuclide metal, B is a spacer linked to N-terminal of C or a covalent bond and C is a bombesin analog peptide antagonist having a sequence as claimed, where further x is an integer from 1 to 3 and n is an integer from 1 to 6. [A-(B)n]x—C (I)
A polymer composition for solar cell and flexible electronics devices, where the polymer is a p-type conducting polymer. The p-type polymer comprises a benzothiadiazole acceptor and indeno-fluorene donor. Further, a solar cell and flexible electronic device article may be made from the polymer.
The present invention relates to a new process for preparing condensation resins, constructed formally from urea, formaldehyde, and CH-acidic aldehydes.
Polyisocyanate-based polymers are formed by curing a reaction mixture containing at least one polyisocyanate and at least one isocyanate-reactive compound having at least two isocyanate-reactive groups in the presence of a copper catalyst that contains at least one copper atom associated with a polydentate ligand that contains at least one nitrogen-containing complexing site.
Alkoxylation products, their preparation, compositions comprising these alkoxylation products, and the use thereof as or for producing adhesives and sealants.
A curable composition comprises (a) at least one polyorganosiloxane, fluorinated polyorganosiloxane, or combination thereof comprising reactive silane functionality comprising at least two hydroxysilyl moieties; (b) at least one polyorganosiloxane, fluorinated polyorganosiloxane, or combination thereof comprising reactive silane functionality comprising at least two hydrosilyl moieties; and (c) at least one photoactivatable composition comprising at least one organoborate salt selected from tetraarylborate, triarylorganoborate, diaryldiorganoborate, and aryltriorganoborate salts (and combinations thereof) of at least one base selected from amidines, guanidines, phosphazenes, proazaphosphatranes, and combinations thereof; wherein at least one of the components (a) and (b) has an average reactive silane functionality of at least three.
Disclosed are molecular and polymeric compounds having desirable properties as semiconducting materials. Such compounds can exhibit desirable electronic properties and possess processing advantages including solution-processability and/or good stability.
In a process for producing polyethylene having a molecular weight of at least 3×105 g/mol as determined by ASTM 4020, ethylene is contacted under polymerization conditions with a slurry of a catalyst composition in at least one hydrocarbon. The catalyst composition comprises a Group 4 metal complex of a phenolate ether ligand and the slurry includes from about 5 to less than 40 ppm per liter of a compound effective to increase the conductivity of said at least one hydrocarbon.
The present invention relates to a production method for efficiently obtaining an acrylic acid-based polymer having a narrow molecular mass distribution and a low molecular mass, without using a large amount of chain transfer agent. A method for continuously producing an acrylic acid-based polymer obtained by continuously polymerizing a monomer having acrylic acid as an essential component, characterized in that a liquid feed pump applies a mechanical load of 0.5 to 2.5 kJ/L to the liquid discharged from the outlet of a reactor. An acrylic acid-based polymer having fewer high-molecular-mass components, excellent dispersion and other properties, and a low molecular mass is thereby obtained.
A polymer reactor-blend comprising at least a first component having a polydispersity index of greater than about 20 and is present in an amount of from about 1 wt. % to about 99 wt. % based on the total weight of the polymer and a second component having a polydispersity index of less than about 20 and is present in an amount of from about 1 wt. % to about 99 wt. % based on the total weight of the polymer wherein a molecular weight distribution of the second component lies within a molecular weight distribution of the first component.
The invention relates to radiation curable coating systems on the basis of aqueous polyurethane dispersions, to a method for the production thereof, to the use of the coating systems as paints and/or adhesives, and to objects and substrates provided with said paints and/or adhesives.
Disclosed is an aqueous polyurethane dispersion obtained by dispersing in water a reaction product obtained by reacting a reaction mixture comprising at least one organic, aliphatic, cycloaliphatic or aromatic di, tri or poryisocyanate, at least one isocyanate reactive polycarbonate diol, triol or polyol, at least one compound comprising at least one isocyanate reactive group and at least one free radically polymerizable unsaturated group, and at least one compound comprising at least one isocyanate reactive group and at least one at least dispersing active group, and optionally at least one compound comprising at least two isocyanate reactive groups and having a molecular weight of less than 1000 g/mol.
After a cyclopentadiene compound and a vinyl aromatic compound are thermally polymerized, the obtained copolymer is subjected to a hydrogenation reaction to form a hydrogenated product. After most of the hydrogenation solvent is separated by a solvent evaporation tank from the hydrogenated product, an additive separately prepared by dissolving an antioxidant is added to the hydrogenated product to form a mixture. While the hydrogenation solvent is a naphthenic solvent, the additive is prepared by dissolving the antioxidant in an aromatic additive solvent having the same carbon atoms as those of the hydrogenation solvent. Then, the low-molecular-weight component as well as the remaining hydrogenation solution and the additive solvent are separated by a thin-film evaporator from the mixture. The obtained molten resin is pelletized to produce hydrogenated petroleum resin pellets. The time for uniformly blending the antioxidant can be shortened.
Composite material that contain epoxy resin which is toughened and strengthened with thermoplastic materials and a blend of insoluble particles. The uncured matrix resins include an epoxy resin component, a soluble thermoplastic component, a curing agent and an insoluble particulate component composed of elastic particles and rigid particles. The uncured resin matrix is combined with a fibrous reinforcement and cured/molded to form composite materials that may be used for structural applications, such as primary structures in aircraft.
Polyamide molding materials for transparent molding parts. The materials comprise transparent copolyamides that contain: (A) 40 to 100 wt % of at least one transparent copolyamide with a glass transition temperature (Tg) of at least 80° C. and not more than 150° C., composed of at least two diamines that are different from each other, wherein the at least two diamines are a mixture of (a) 50 to 90 mol % bis-(4-amino-3-methylcyclohexyl)methane (MACM) and/or bis-(4-amino-3-ethylcyclohexyl)methane (EACM) and/or bis-(4-amino-3,5-dimethylcyclohexyl)methane (TMACM) and b) 10 to 50 mol % aliphatic diamine having 9 to 14 carbon atoms, in particular decandiamine, particularly preferably at least 20 mol % decandiamine, each relative to the total amount of diamines, and of one or more aliphatic dicarboxylic acids, having 6 to 36 carbon atoms, (B) 0 to 60 wt % of at least one further polymer, (C) 0 to 10 wt % of additives, the sum of the components (A), (B) and (C) totaling 100% by weight.
Formaldehyde-free binder compositions are described that include an aldehyde or ketone, a nitrogen-containing salt of an inorganic acid, and an acidic compound. The acidic compound may be an organic acid, such as maleic acid or citric acid among others. The acidic compound is supplied in quantities that lower the pH of the binder composition to about 5 or less. The binder compositions may be used in methods of binding fiberglass and the resulting fiberglass products have an improved tensile strength due to the addition of the acidic compound.
A rubber composition for the manufacture of tires, based on a blend of at least one diene elastomer chosen from natural rubber and synthetic polyisoprene and of one or more diene elastomers chosen from the group consisting of polybutadienes, butadiene copolymers and isoprene copolymers, on one or more reinforcing fillers and on a vulcanization system, the said vulcanization system comprising one or more thiazoline compounds of formula:
The invention relates to an epoxidized composition and a process for producing the same. The epoxidized composition is useful as a plasticizer for thermoplastics such as polyvinyl chloride (PVC) and other polymers. The process includes forming a blend containing one or more fatty acid esters and one or more bio-based oils; and epoxidizing the blend to form the epoxidized composition. This process has several advantages over a process of forming a blend of already epoxidized fatty acid esters and epoxidized bio-based oils.
In order to provide a rubber composition in which dispersibility of silica is improved and in which a viscosity of an unvulcanized rubber is lowered and a heat build-up improving effect of a vulcanized rubber is well exerted, and a tire prepared by using the rubber composition, the rubber composition is endowed with a constitution in which 100 parts by mass of at least one rubber component selected from natural rubber and/or diene base synthetic rubbers are compounded with 55 to 200 parts by mass of silica and 0.5 to 15 parts by mass of at least one of alkanolamines represented by the following Formula (I): [in Formula (I), R1 represents an alkyl group or an alkenyl group having 1 to 24 carbon atoms, and the above alkyl group and alkenyl group may be any of a linear group, a branched group and a cyclic group; m and n represent an average addition molar number, and m and n are numerical values which represent m+n=1 to 20].
A composition for making polymeric fiber membranes, for use in non-cryogenic separation of gases, substantially improves product flow, with only a small decrease in the recovery ratio. The composition is a spin dope including tetrabromo bis-phenol A polycarbonate (TBBA-PC) and tetrabromo bishydroxyphenylfluorene polycarbonate (TBBHPF-PC), in proportions, by weight, ranging (in percent) from about 60/40 to 40/60, and n-methyl pyrrolidinone (NMP) and triethylene glycol (TEG), wherein the ratio of the amounts of NMP to TEG, by weight, is in the range of about 1.6-2.5. The spin dope is used to make hollow fibers for use in gas-separation membrane modules.
Generally, compositions and methods of producing dimensionally stable three dimensional objects using an additive build up process. Specifically, materials combinable in an additive build up process using a materials printer for the production of stable three dimensional molds useful in the production of molded or formed parts.
Provided is a polymer material having superior water wettability and lubricity, and enabling persistence of the same by allowing the surfactant to be retained by the polymer material so as not to be gradually released. The present invention is directed to a polymer material including:[I] a polymer having a constitutional unit derived from (A) a polymerizable compound having an acryloyloxy group and not having a silicon atom; and [II] a surfactant. The content of the surfactant [II] is preferably 0.05% by mass or greater and 1% by mass or less. The surfactant [II] is preferably a nonionic surfactant having a polyoxyethylene group.
Polyurethane foams are made using a biuret-modified MDI and/or PMDI as the isocyanate component. The isocyanate is characterized by having a high content of biuret-containing oligomers and, preferably, a low proportion (if any) of biuret-urea oligomers. Flexible, resilient foams made using this biuret-modified isocyanate perform well on flammability tests such as the UNI 9175 CS. E. RF4 test, even without added flame retardants.
A method for making polyethylene aerogels, including high molecular weight aerogels, commences by in a hydrocarbon solvent (e.g., toluene or benzene) in which polyethylene is insoluble at room temperature, adding polyethylene to the solvent heated to a temperature at which said polyethylene is soluble to form a reaction mixture. A free-radical catalyst is added to the reaction mixture and the reaction mixture is held until the desired gelation of the polyethylene has been achieved. The reaction mixture is cooled to about room temperature; and the hydrocarbon solvent is replaced with a gas (e.g., CO2 or air) to form the polyethylene aerogel. Optionally, the cooled reaction mixture can be contacted with an anti-solvent for polyethylene to replace the hydrocarbon solvent with the anti-solvent. Silica aerogel particles can be encapsulated in polyethylene aerogel by adding the particles to the polyethylene gelation reaction mixture.
Compounds, compositions, and methods comprising a polyamine compound are described, which may be used to kill, disperse, treat, reduce biofilms, and/or inhibit or substantially prevent biofilm formation. In certain aspects, the present invention relates to compounds, compositions, and methods comprising polyamine compounds that have antimicrobial or dispersing activity against a variety of bacterial strains capable of forming biofilms.
Provision of an N-acyl basic amino acid dispersion superior in dispersibility. The present invention provides a production method of an N-acyl basic amino acid dispersion having a pH of 2 to 12, comprising (1) a step of dissolving an N-acyl basic amino acid in a base solution, and (2) a step of mixing the obtained N-acyl basic amino acid solution with one or more equivalents of an acid relative to the base.
A stable liquid pharmaceutical formulation contains an N-phenylpyrazole derivative, a crystallization inhibitor/viscolizer, and a solvent/co-solvent system including a glycol ether solvent and at least one mono alkyl ester co-solvent; an improved topical veterinary applicator system; and the use of the formulation for the prevention and treatment of infestations with fleas and ticks.
The present invention relates to certain compositions of a 5-HT2A serotonin receptor modulator and methods for their preparation. The compositions disclosed herein are useful for increasing slow wave sleep, improving sleep consolidation, improving sleep maintenance and improving sleep quality, and for treating insomnia and related sleep disorders, dyssomnias, parasomnias and nonrestorative sleep and the like. The compositions disclosed herein are further useful for treating platelet aggregation, coronary artery disease, myocardial infarction, transient ischemic attack, angina, stroke, atrial fibrillation, thrombosis, asthma or symptoms thereof, agitation or symptoms thereof, behavioral disorders, drug induced psychosis, excitative psychosis, Gilles de la Tourette's syndrome, manic disorder, organic or NOS psychosis, psychotic disorders, psychosis, acute schizophrenia, chronic schizophrenia, NOS schizophrenia and related disorders, diabetic-related disorders and progressive multifocal leukoencephalopathy and the like.
Compounds of formula (I), combinations and uses thereof for disease therapy, or a pharmaceutically acceptable salt, solvate or polymorph thereof, including all tautomers and stereoisomers thereof wherein: R1 represents and R2, R3, R4, R5, R6, X1, X2, X3, X4, Y and Z are as defined throughout the description and the claims.
Provided is a compound represented by the formula (1): wherein R1 and R2 are each independently a hydrogen atom or a straight chain alkyl group having a carbon number of 1-3, R3 is a hydrogen atom, an alkyl group having a carbon number of 1-4, an alkoxyalkyl group, an aryl group, a halogen atom or a haloalkyl group, or a pharmaceutically acceptable salt thereof, which has, unlike known PGI2 analogs, a selective EP4 agonist action, and a medicament containing the compound, which is useful for the prophylaxis and/or treatment of immune diseases, diseases of the digestive tract, cardiovascular diseases, cardiac diseases, respiratory diseases, neurological diseases, ophthalmic diseases, renal diseases, hepatic diseases, bone diseases, skin diseases and the like.
Antimicrobial compositions based on the synergistic combination of 2-methyl-3-isothiazolone and selected commercial microbicides where the compositions are substantially free of halogenated 3-isothiazolone, are disclosed. Particularly preferred are combinations of 2-methyl-3-isothiazolone together with benzoic acid, citric acid, sorbic acid, 1,2-dibromo-2,4-dicyanobutane, 1,3-dimethylol-5,5-dimethylhydantoin, phenoxyethanol, benzyl alcohol, zinc pyrithione or climbazole, that provide enhanced microbicidal efficacy at a combined active ingredient level lower than that of the combined individual 3-isothiazolone and commercial microbicide effective use levels.
Inhibitors of the soluble epoxide hydrolase (sEH) are provided that incorporate multiple pharmacophores and are useful in the treatment of diseases. In some embodiments, the present invention provides a method for monitoring the activity of a soluble epoxide hydrolase, the method including contacting the soluble epoxide hydrolase with an amount of a compound of the present invention sufficient to produce a detectable change in the fluorescence of the soluble epoxide hydrolase by interacting with one or more tryptophan residues present in the catalytic site of said sEH.
The present invention relates to substituted heterocyclic derivative compounds, compositions comprising said compounds, and the use of said compounds and compositions for epigenetic regulation by inhibition of bromodomain-mediated recognition of acetyl lysine regions of proteins, such as histones. Said compositions and methods are useful for the treatment of cancer and neoplastic disease.
Novel aryl, heteroaryl, and non-aromatic heterocyle substituted tetrahydroisoquinolines are described in the present invention. These compounds are used in the treatment of various neurological and physiological disorders. Methods of making these compounds are also described in the present invention.
There are provided certain bicyclic heterocyclic compounds that act as M1 muscarinic receptor modulators. Compositions containing these compounds and their use are also disclosed.
A method administers quaternary ammonium anti-cholinergic muscarinic receptor antagonists in combination with acetyl-cholinesterase inhibitors to treat either cognitive impairment or acute delirium. This therapy results in a modification of a cognitive disorder or disease, namely a slow down in the disease progression. In one preferred embodiment, the disease is dementia with Lewy Bodies. New formulations for quaternary ammonium anti-cholinergic muscarinic receptor antagonists are also disclosed.
Compounds of formula (I): wherein R1, R2, R3, R4, R7, R6, R7, R8, R9, A, X and Y as defined herein are provided as useful for the treatment of cancer or for the manufacture of anti-cancer agents.
The present invention relates to certain DPP-4 inhibitors for treating and/or preventing oxidative stress, vascular stress and/or endothelial dysfunction as well as to the use of such DPP-4 inhibitors in treatment and/or prevention of diabetic or non-diabetic patients, including patient groups at risk of cardiovascular and/or renal disease.
The disclosure generally relates to compounds of formula I, including compositions and methods for treating human immunodeficiency virus (HIV) infection. The disclosure provides novel inhibitors of HIV, pharmaceutical compositions containing such compounds, and methods for using these compounds in the treatment of HIV infection.
Compounds I and II, as well as prodrugs, hydrates, solvates, N-oxides, salts and pharmaceutical compositions containing them, are useful for treating vitiligo. In certain embodiments, the compounds are provided in topical compositions.
The invention provides (i) a method of treating metabolic syndrome in an animal, (ii) a method of suppressing the appetite of an animal, (iii) a method of treating obesity in an animal, (iv) a method of reducing the weight of an animal in need thereof, (v) a method of reducing a blood lipid level in an animal in need thereof, (vi) a method of treating non-alcoholic steatohepatitis in an animal, and (vii) a method of inhibiting adipogenesis. The methods comprise administering an effective amount of an active ingredient, wherein the active ingredient comprises a diketopiperazine, a prodrug of a diketopiperazine or a pharmaceutically-acceptable salt of either of them to the animal. The invention also provides a kit comprising a container holding a diketopiperazine, a prodrug of a diketopiperazine or a pharmaceutically-acceptable salt of either of them; and instructions for administration. The diketopiperazines have the formula given in the application.
Novel heterocyclic compounds having the Formula I: wherein A, B, D, E, G, K, L, M, Q, T, X, Y and Z are as defined herein, which exhibit a dopamine receptor (preferably a D4 receptor) agonistic activity, and/or a PDE5 inhibitory activity, processes of preparing same, pharmaceutical compositions containing same and uses thereof in the treatment of sexual disorders such as decreased libido, orgasm disorder and erectile dysfunction are disclosed.
The present invention embraces Niemann-Pick C1-like 1 protein antagonists and agents that inhibit hepatic virus infection for use in the prevention and treatment of a hepatic virus infection.
Disclosed is a pharmaceutical composition containing a compound represented by the general formula (I) below or a pharmacologically acceptable salt thereof, while having improved dissolvability. Specifically disclosed is a pharmaceutical composition containing (A) a compound represented by the general formula (I) below or a pharmacologically acceptable salt thereof, and (B) a low-substituted hydroxypropyl cellulose.
Methods and compositions for the prevention and treatment of liver damage or disease in a subject in need thereof are provided. The methods involve providing the sulfated oxysterol 25-hydroxycholesterol-3-sulfate (25HC3S) to the subject e.g. by 1) administering 25HC3S to the subject; or 2) overexpressing, in the subject, the hydroxysterol sulfotransferase enzyme SULT2B1b, which catalyzes the sulfation of 25-hydroxycholesterol (25HC) to form 25HC3S.
The present invention relates to compounds of Formula (I), methods for preparing these compounds, compositions, intermediates and derivatives thereof and for treating a condition including but not limited to ankylosing spondylitis, artherosclerosis, arthritis (such as rheumatoid arthritis, infectious arthritis, childhood arthritis, psoriatic arthritis, reactive arthritis), bone-related diseases (including those related to bone formation), breast cancer (including those unresponsive to anti-estrogen therapy), cardiovascular disorders, cartilage-related disease (such as cartilage injury/loss, cartilage degeneration, and those related to cartilage formation), chondrodysplasia, chondrosarcoma, chronic back injury, chronic bronchitis, chronic inflammatory airway disease, chronic obstructive pulmonary disease, diabetes, disorders of energy homeostasis, gout, pseudogout, lipid disorders, metabolic syndrome, multiple myeloma, obesity, osteoarthritis, osteogenesis imperfecta, osteolytic bone metastasis, osteomalacia, osteoporosis, Paget's disease, periodontal disease, polymyalgia rheumatica, Reiter's syndrome, repetitive stress injury, hyperglycemia, elevated blood glucose level, and insulin resistance.
The present invention relates to a process of synthesis of α-sialyl oligosaccharides and in particular of 6′-sialyllactose and its salts comprising a step of coupling by Koenigs-Knorr reaction under conditions that allow its use on an industrial scale.
The present invention concerns a TCTP antagonist, in particular a nucleic acid targeting an m RNA encoding Translationally-Controlled Tumor Protein (TCTP), wherein said nucleic acid is capable of reducing the amount of TCTP in cells, for use in the treatment or prevention of hormone-independent cancer or chemo-resistant cancer, such as an androgen-independent prostate cancer.
The invention provides for peptides from syndecan 4 and methods of use therefor. These peptides can inhibit α6β4 integrin interaction with EGFR, thereby preventing tumor cell growth and tissue invasion.
The invention meets the needs above by providing a surfactant system, mixture or blend that can be used as a part of a soaking composition. The surfactant system is capable of forming emulsions with, and thus removing, oily and greasy stains. In a preferred embodiment the surfactant compositions of the invention can remove non-trans fat and fatty acid stains. The invention involves foaming soaking compositions that have some or part of the anionic surfactant present in the same replaced with an extended chain anionic surfactant.
Capture compounds and collections thereof and methods using the compounds for the analysis of biomolecules are provided. In particular, collections, compounds and methods are provided for analyzing complex protein mixtures, such as the proteome. The compounds are multifunctional reagents that provide for the separation and isolation of complex protein mixtures. Automated systems for performing the methods also are provided.
The present invention provides a method for post-emergence selective crabgrass control by applying a composition comprising a first herbicide and a second herbicide in which the first herbicide is 2,4-dinitro-N3,N3-dipropyl-6-(trifluoromethyl)-1,3-benzenediamine and the second herbicide is N-[2,4-dichloro-5-[4-(difluoromethyl)-4,5-dihydro-3-methyl-5-oxo-1H-1,2,4-triazol-1-yl]phenyl]methanesulfonamide to a locus where one to two leaf growth stage crabgrass is present.
The present invention relates to methods and compositions for supplementing the soil/diet of plants in order to enhance plant growth, yield, hardening, as well as the recovery of plants which undergo transplantation. The present invention provides ribose and other pentose sugars and their derivatives, alone or in combination with other carbohydrates, electrolytes, minerals, enzymes, micronutrients, macronutrients, or other ingredients to enhance plant growth, yield, hardening, and aid in the recovery during and following transplantation.
Provided are an adsorptive carbon which can effectively adsorb vivotoxins such as advanced glycation end products (AGEs), and an adsorbent containing the adsorptive carbon as an active ingredient. The adsorptive carbon according to the present invention has a total pore volume of 0.10 to 1.0 mL/g, an average pore diameter of 1.0 to 2.0 nm, and an absorbance of an infrared absorption band at 1650-1800 cm−1 of no less than 0.005.
The present invention relates to a catalyst composition for conversion of vegetable oils to hydrocarbon products in the diesel boiling range, comprising a porous support; Group III A or VA element in the range of 1-10 wt %; Group VI B elements in the range of 1 to 20 wt %; Group VIII B elements in range of 0.01 to 10 wt %. The present invention further provides the process for preparing the catalyst composition for conversion of vegetable oils to hydrocarbon products in the diesel boiling range. The present invention also provides the process for conversion of vegetable oils to hydrocarbon products in the diesel boiling range using the catalyst composition or discarded refinery spent hydro-treating catalyst.
A structure may include a plurality of first fiber bundles, a plurality of second fiber bundles, and a plurality of connecting threads. The first fiber bundles may extend substantially parallel to each other. The second fiber bundles may extend substantially parallel to each other and substantially perpendicular to the first fiber bundles. The connecting threads may engage the first fiber bundles and the second fiber bundles such that at least one of the connecting threads is continuously wrapped around each of the first fiber bundles in a helical pattern. The at least one of the connecting threads may extend across a width of each of the second fiber bundles, and may thereby secure the second fiber bundles to each of the first fiber bundles. The first and second fiber bundles may be embedded in a construction material and adapted to reinforce the construction material.
A method of etching a substrate by plasma via a mask having a predetermined pattern at back of a silicon layer of the substrate, a semiconductor device being formed at front of which supported by a support substrate, includes a main etching step in which plasma is generated by supplying a process gas including a mixed gas whose flow ratio of fluorine compound gas, oxygen gas and silicon fluoride gas is 2:1:1.5 or a process gas including a mixed gas in which at least the ratio of one of the oxygen gas and the silicon fluoride gas, using the fluorine compound gas as a standard, is larger than the above ratio, and the substrate is etched by the plasma; and an over etching step in which the substrate is further etched by plasma while applying a high frequency for bias whose frequency is less than or equal to 400 kHz.
A method of forming a semiconductor device includes first preliminary holes over an etch target, the first preliminary holes arranged as a plurality of rows in a first direction, forming dielectric patterns each filling one of the first preliminary holes, sequentially forming a barrier layer and a sacrificial layer on the dielectric patterns, forming etch control patterns between the dielectric patterns, forming second preliminary holes by etching the sacrificial layer, each of the second preliminary holes being in a region defined by at least three dielectric patterns adjacent to each other, and etching the etch target layer corresponding to positions of the first and second preliminary holes to form contact holes.
A method for manufacturing a sloped structure is disclosed. The method includes the steps of: (a) forming a sacrificial film above a substrate; (b) forming a first film above the sacrificial film; (c) forming a second film having a first portion connected to the substrate, a second portion connected to the first film, and a third portion positioned between the first portion and the second portion; (d) removing the sacrificial film; and (e) bending the third portion of the second film after the step (d), thereby sloping the first film with respect to the substrate.
Disclosed are metal-containing precursors having the formula Compound (I) wherein: —M is a metal selected from Ni, Co, Mn, Pd; and —each of R-1, R2, R3, R4, R5, R6, R7, R8, R9, and R10 are independently selected from H; a C1-C4 linear, branched, or cyclic alkyl group; a C1-C4 linear, branched, or cyclic alkylsilyl group (mono, bis, or tris alkyl); a C1-C4 linear, branched, or cyclic alkylamino group; or a C1-C4 linear, branched, or cyclic fluoroalkyl group. Also disclosed are methods of synthesizing and using the disclosed metal-containing precursors to deposit metal-containing films on a substrate via a vapor deposition process.
Embodiments of the present invention provide a method of forming contact structure for transistor. The method includes providing a semiconductor substrate having a first and a second gate structure of a first and a second transistor formed on top thereof, the first and second gate structures being embedded in a first inter-layer-dielectric (ILD) layer; epitaxially forming a first semiconductor region between the first and second gate structures inside the first ILD layer; epitaxially forming a second semiconductor region on top of the first semiconductor region, the second semiconductor region being inside a second ILD layer on top of the first ILD layer and having a width wider than a width of the first semiconductor region; and forming a silicide in a top portion of the second semiconductor region.
A micro device transfer head array and method of forming a micro device transfer array from an SOI substrate are described. In an embodiment, the micro device transfer head array includes a base substrate and a patterned silicon layer over the base substrate. The patterned silicon layer may include a silicon interconnect and an array of silicon electrodes electrically connected with the silicon interconnect. Each silicon electrode includes a mesa structure protruding above the silicon interconnect. A dielectric layer covers a top surface of each mesa structure.
A method for performing silicidation of gate electrodes includes providing a semiconductor device having first and second transistors with first and second gate electrodes formed on a semiconductor substrate, forming an oxide layer on the first and second gate electrodes and the semiconductor substrate, forming a cover layer on the oxide layer, and back etching the cover layer to expose portions of the oxide layer above the first and second gate electrodes while maintaining a portion of the cover layer between the first and second gate electrodes. Furthermore, the exposed portions of the oxide layer are removed from the first and second gate electrodes to expose upper portions of the first and second gate electrodes, while maintaining a portion of the oxide layer between the first and second gate electrodes, and a silicidation of the exposed upper portions of the first and second gate electrodes is performed.
Approaches for enabling epitaxial growth of silicon fins in a device (e.g., a fin field effect transistor device (FinFET)) are provided. Specifically, approaches are provided for forming a set of silicon fins for a FinFET device, the FinFET device comprising: a set of gate structures formed over a substrate, each of the set of gate structures including a capping layer and a set of spacers; an oxide fill formed over the set of gate structures; a set of openings formed in the device by removing the capping layer and the set of spacers from one or more of the set of gate structures; a silicon material epitaxially grown within the set of openings in the device and then planarized; and wherein the oxide fill is etched to expose the silicon material and form the set of fins.
A method for direct bonding between a first element and a second element, including at least the following steps: deposition of at least one first porous layer on at least one face of the first element, where the first porous layer is compressible, production of at least one bonding layer on the first porous layer, rigid connection by direct bonding of the second element with the first bonding layer.
A semiconductor structure is located in a recess of a substrate. The semiconductor structure includes a liner, a silicon rich layer and a filling material. The liner is located on the surface of the recess. The silicon rich layer is located on the liner. The filling material is located on the silicon rich layer and fills the recess. Furthermore, a semiconductor process forming said semiconductor structure is also provided.
A method of fabricating a fin-like field-effect transistor (FinFET) device is disclosed. A plurality of mandrel features are formed on a substrate. First spacers are formed along sidewalls of the mandrel feature and second spacers are along sidewalls of the first spacers. Two back-to-back adjacent second spacers separate by a gap in a first region and merge together in a second region of the substrate. A dielectric feature is formed in the gap and a dielectric mesa is formed in a third region of the substrate. A first subset of the first spacer is removed in a first cut. Fins and trenches are formed by etching the substrate using the first spacer and the dielectric feature as an etch mask.
A method includes etching a semiconductor substrate to form a recess in the semiconductor substrate, and reacting a surface layer of the semiconductor substrate to generate a reacted layer. The surface layer of the semiconductor substrate is in the recess. The reacted layer is then removed. An epitaxy is performed to grow a semiconductor material in the recess.
Disclosed herein is a method for fabricating a silicon nanowire field effect transistor based on a wet etching. The method includes defining an active region; depositing a silicon oxide film as a hard mask, forming a pattern of a source and a drain and a fine bar connecting the source and the drain; transferring the pattern on the hard mask to a silicon substrate by performing etching process for the silicon substrate; performing ion implanting; etching the silicon substrate by wet etching, so that the silicon fine bar connecting the source and the drain is suspended; reducing the silicon fine bar to a nano size to form a silicon nanowire; depositing a polysilicon film; forming a polysilicon gate line acrossing the silicon nanowire by electron beam lithography and forming a structure of nanowire-all-around; forming a silicon oxide sidewall at both sides of the polysilicon gate line, by depositing a silicon oxide film and subsequently etching the silicon oxide film; forming the source and the drain by using ion implantation and high temperature annealing, so that the silicon nanowire field effect transistor is finally fabricated. The method is compatible with a conventional integrated circuit fabrication technology. The fabrication process is simple and convenient, and has a short cycle.
Integrated circuit devices including Fin field effect transistors (finFETs) and methods of forming those devices are provided. The methods may include forming a fin on a substrate and forming a gate line on the fin. The method may also include forming a first recess in the fin having a first width and a first depth and forming a second recess in the first recess having a second width that is less than the first width and having a second depth that is greater than the first depth. The method may further include forming a source/drain region in the first and second recesses.
A thin film transistor, a thin film transistor array panel including the same, and a method of manufacturing the same are provided, wherein the thin film transistor includes a channel region including an oxide semiconductor, a source region and a drain region connected to the channel region and facing each other at both sides with respect to the channel region, an insulating layer positioned on the channel region, and a gate electrode positioned on the insulating layer, wherein an edge boundary of the gate electrode and an edge boundary of the channel region are substantially aligned.
Precursors for use in depositing antimony-containing films on substrates such as wafers or other microelectronic device substrates, as well as associated processes of making and using such precursors, and source packages of such precursors. The precursors are useful for deposition of Ge2Sb2Te5 chalcogenide thin films in the manufacture of nonvolatile Phase Change Memory (PCM) or for the manufacturing of thermoelectric devices, by deposition techniques such as chemical vapor deposition (CVD) and atomic layer deposition (ALD).
Embodiments of the present invention include a method. The method includes heating a layer stack. The layer stack includes a first layer comprising cadmium and tin, a metal layer disposed over the first layer, and a window layer disposed over the metal layer. Heating the stack includes transforming at least a portion of the first layer from an amorphous phase to a crystalline phase. Heating may be performed using any of various configurations, such as, for example, heating an individual stack, or using a face-to-face configuration of multiple stacks. The stack may be used for fabricating a photovoltaic device.
An embodiment of the invention provides a chip package, which includes: a substrate having an upper surface and a lower surface; a passivation layer located overlying the upper surface of the substrate; a plurality of conducting pad structures disposed overlying the upper surface of the substrate, wherein at least portions of upper surfaces of the conducting pad structures are exposed; a plurality of openings extending from the upper surface towards the lower surface of the substrate; and a plurality of movable bulks located between the openings and connected with the substrate, respectively, wherein each of the movable bulks is electrically connected to one of the conducting pad structures.
Disclosed is a light-emitting device comprising a light-emitting element (10) composed of a gallium nitride compound semiconductor having an emission peak wavelength of not less than 430 nm; a molded body (40) provided with a recessed portion having a bottom surface on which the light-emitting element (10) is mounted and a lateral surface; and a sealing member (50) containing an epoxy resin including a triazine derivative epoxy resin, or a silicon-containing resin. The molded body (40) is obtained by using a cured product of a thermosetting epoxy resin composition essentially containing an epoxy resin including a triazine derivative epoxy resin, and has a reflectance of not less than 70% at the wavelengths of not less than 430 nm.
Some embodiments provide methods, process, systems and apparatus for use in testing multi-axis Micro Electro Mechanical Systems (MEMS) devices. In some embodiments, methods of testing are provided, comprising: selecting, according to a test specification and a test program, at least a first MEMS device on a substrate comprising a plurality of MEMS formed relative to the substrate and applying one or more electrical probes to the first MEMS device; providing power to the first MEMS device through the one or more electrical probes; measuring output signals of the first MEMS device; applying a force to the first MEMS device using a force actuator; measuring a set of output signals of the first MEMS device based on the applied force; and processing test data and generating output test results according to the test specification and test program.
Methods and systems for selectively capturing analytes, such as cells, e.g., circulating tumor cells (CTCs), from fluid samples are disclosed. The methods include contacting the sample with an analyte binding moiety that selectively binds to the analytes; optionally separating first components of the sample including a majority of the analytes bound to the binding moieties from second components of the sample using size-based separation, e.g., in a microfluidic channel; adding to the first components of the sample a plurality of binding agents under conditions that enable a plurality of the binding agents to be linked to the analyte binding moieties to form multivalent tagging agents bound to the analyte; passing the first components of the sample past a surface to which is attached a plurality of capture agents that selectively bind to the binding agents; and capturing the analytes by providing conditions that enable the multivalent tagging agents bound to the analytes to bind to one or more of the capture agents.
A method for analyzing the liquefied petroleum gas includes the following steps. Provide a sample of the liquefied petroleum gas, and one main component group of the liquefied petroleum gas includes at least one sub component group. Analyze the sample of the liquefied petroleum gas so as to obtain a first measured THC corresponding to the main component group and a second measured THC corresponding to the sub component group. Obtain a regressed THC according to the second measured THC and a predetermined relationship of THC. Obtain a result of THC according to the first measured THC, the regressed THC, and a predetermined range of THC. The predetermined range of THC corresponds to the main component group. The device for analyzing the liquefied petroleum gas includes an inlet, a multiposition valve, a first column, a second column, an analyzing apparatus, and a computing unit.
The invention relates to the quantitative measurement of steroidal compounds by mass spectrometry. In a particular aspect, the invention relates to methods for quantitative measurement of steroidal compounds from multiple samples by mass spectrometry.
An object of the present invention is to provide an artificial tissue construct that has means for transporting nutrients, oxygen, waste products, or the like and is viable in vivo. The present invention relates to a tissue construct formed in vitro, which comprises a vascular layer, a basal membrane layer, and a tissue-forming cell layer.
Disclosed are systems and methods for coupling translation of a target gene to a detectable response gene. A version of the invention includes a translation-coupling cassette. The translation-coupling cassette includes a target gene, a response gene, a response-gene translation control element, and a secondary structure-forming sequence that reversibly forms a secondary structure masking the response-gene translation control element. Masking of the response-gene translation control element inhibits translation of the response gene. Full translation of the target gene results in unfolding of the secondary structure and consequent translation of the response gene. Translation of the target gene is determined by detecting presence of the response-gene protein product. The invention further includes RNA transcripts of the translation-coupling cassettes, vectors comprising the translation-coupling cassettes, hosts comprising the translation-coupling cassettes, methods of using the translation-coupling cassettes, and gene products produced with the translation-coupling cassettes.
A device is provided for use with a tissue penetrating system and/or a metering device for measuring analyte levels. The device comprises a cartridge and a plurality of analyte detecting members mounted on the cartridge. The cartridge may have a radial disc shape. The cartridge may also be sized to fit within the metering device. The analyte detecting members may be optical system using fluorescence lifetime to determine analyte levels. In one embodiment, the device may also include a fluid spreader positioned over at least a portion of the analyte detecting member to urge fluid toward one of the detecting members. A plurality of analyte detecting members may be used. Each analyte detecting member may be a low volume device.
In one embodiment, the invention is to a sample metering device, comprising a sample holding chamber oriented between a sample entry port and a sample isolation unit and having a diluent introduction port disposed therebetween for introduction of a diluent into the sample holding chamber. The volume within the sample holding chamber between the diluent introduction port and the sample isolation unit defines a metered volume of a sample for analysis. In another embodiment, the invention is to an apparatus and method for rapid determination of analytes in liquid samples by various assays including immunoassays incorporating a sample dilution feature, preferably suitable for low range sample dilution, and preferably capable of being used in the point-of-care diagnostic field.
This disclosure provides compositions and methods for culturing microorganisms. The disclosure includes mixtures of different microorganisms, especially mixtures of cyanobacteria with fermentative microorganisms. For example, methods and compositions related to co-cultures of yeast and cyanobacteria are provided. Also provided are feedstocks derived from cyanobacteria as well as methods of making such feedstocks and methods of culturing microorganisms in such feedstocks.
The present disclosure identifies methods and compositions for modifying photoautotrophic organisms as hosts, such that the organisms efficiently produce alkanes, and in particular the use of such organisms for the commercial production of alkanes and related molecules. Other materials, methods, and compositions are also described.
This invention relates to novel α-galactosidases for the enzymatic removal of the immunodominant monosaccharides on blood products and tissues. Specifically this invention provides a novel family of α3 glycosidases, used for the enzymatic removal of type B antigens from blood group B and AB reactive blood products, and the Galili antigen from non-human animal tissues, thereby converting these to non-immunogenic cells and tissues suitable for transplantation.
Compositions and methods are provided for enzymes with altered properties that involve a systematic approach to mutagenesis and a screening assay that permits selection of the desired proteins. Embodiments of the method are particularly suited for modifying specific properties of restriction endonucleases such as star activity. The compositions includes restriction endonucleases with reduced star activity as defined by an overall fidelity index improvement factor.
The present invention relates to recombinant bacteria and the uses thereof, particularly for the production of ethanol. The invention also relates to methods for the production of such bacteria, as well as to nucleic acid constructs suitable for such production. The invention specifically relates to bacteria lacking a functional LDH gene and/or containing a recombinant nucleic acid encoding a PDC and ADH. The bacteria of this invention may be produced from any stress-resistant bacteria.
The present invention provides a method for the biological production of glycolic acid from a fermentable carbon source in a microorganism. In one aspect of the present invention, a process for the conversion of glucose to glycolic acid is achieved by the use of a recombinant organism comprising a host E. coli transformed i) to attenuate the glyoxylate consuming pathways to other compounds than glycolate ii) to use an NADPH glyoxylate reductase to convert glyoxylate to glycolate iii) to attenuate the level of all the glycolate metabolizing enzymes and iv) increase the flux in the glyoxylate pathway. In another aspect of the present invention, the process for the production of glycolic acid from a fermentable carbon source, using a recombinant E. coli, is improved by increasing the NADPH availability in the cells. Optionally the glycolic acid produced can be purified through a step of polymerization to at least glycolic acid dimers and recovered by depolymerization from glycolic acid dimers, oligomers and/or polymers.
The invention provides novel methods for making or modifying oils, e.g., plant animal or microbial oils, such as vegetable oils or related compounds, that are low in a particular fatty acid(s), for example, low linoleic oils, linolenic oils, low palmitic oils, low stearic oils or oils low in a combination thereof.
The present invention relates to bio-engineered multi-enzyme complexes having synergistic enzyme activity comprising xylanases and optionally further comprising additional carbohydrate active enzymes. Such complexes are advantageous for degrading recalcitrant cellulosic biomass.
The present invention relates to a method for determining contaminations in a cell culture sample comprising the steps of: a) contacting a sample of a cell culture suspected to comprise contaminations with a composition comprising oligonucleotides under conditions which allow for amplification of polynucleotides, wherein said oligonucleotides comprise oligonucleotides of at least three different groups of oligonucleotides, and b) determining the contaminations based on the amplified polynucleotides obtained by using the oligonucleotide groups of step (a). Moreover, the invention relates to a composition comprising an oligonucleotide mixture. Further encompassed by the present invention is a composition comprising a probe oligonucleotide mixture. Finally, the present invention also relates to kits comprising said oligonucleotide mixtures.
Systems and methods are provided for enhancing the integration of processes for recovering products from algae-derived biomass. The enhanced process integration allows for increased use of input streams and other reagents that are derived from renewable sources. This increases the overall renewable character of the products extracted from the algae-derived biomass. The process integration can include exchange of input streams or energy between an algae processing system and a system for processing non-algal biomass. One example of improving process integration is using oxygenates that are generated in a renewable manner as a reagent for enhancing the algae processing system.
An apparatus, system, and method for magnetic separation of cells are disclosed. By combining inkjet printing technology and magnetic labeling of cells, accurate cell counts are obtained using an optical microscope. Mouse CD4+ lymphocytes are attached to micron sized magnetic beads and printed through a modified, commercial inkjet printer. The labeled cells are then attached to a glass slide covering a permanent magnet. Cell counts can be obtained by use of regular and inverted optical microscopes and imaging software. The magnetically-labeled beads are collected for evaluation on a modified polymer coupon that is placed in front of a permanent magnet and the unlabeled cells fall into an excess container. Flow cytometry results verify the presence of the CD4+ protein on the LBRM-33 lymphocytes membrane. Protein-specific attachment of magnetic microspheres to the lymphocytes is utilized for sorting CD4+ lymphocytes.
In one aspect, the invention provides methods and compositions for the expression of small RNA molecules within a cell using a retroviral vector (FIG. 1A). Small interfering RNA (siRNA) can be expressed using the methods of the invention within a cell. In a further aspect, the invention provides methods for producing siRNA encoding lentivirus where the siRNA activity may interfere with the lentiviral life cycle. In yet a further aspect, the invention provides methods for expression of a small RNA molecule within a cell, such as an siRNA capable of downregulating CCR5, wherein expression of the small RNA molecule is relatively non-cytotoxic to the cell. The invention also includes small RNA molecules, such as an siRNA capable of downregulating CCR5, that are relatively non-cytotoxic to cells.
The invention relates to a method of isolating and analyzing an analyte using an analytical apparatus which comprises modules of different types, wherein any one module of one type has a specific, pre-defined timing for carrying out its workflow.
The RH blood group antigens derive from two genes, RHD and RHCE, that are located at chromosomal position 1p34.1-1p36. In whites, a “cde” haplotype with a deletion of the whole RHD gene occurs with a frequency of about 40%. The relative position of the two RH genes and the location of the RHD deletion was previously unknown. A model for the RH locus was developed using RHD- and RHCE-related nucleotide sequences deposited in nucleotide sequence databases along with PCR and nucleotide sequencing. The open reading frames of both RH genes had opposite orientations. The 3′ ends of the genes faced each other and were separated by about 30,000 base pairs (bp) that contained the SMP1 gene. The RHD gene was flanked by two DNA segments, dubbed Rhesus boxes, that had about 9,000 bp length, 98.6% homology, and identical orientation. The Rhesus box contained the RHD deletion occurring within a stretch of 1,463 bp of identity. A PCR-SSP and a PCR-RFLP for specific detection of the RHD deletion was devised. The molecular structure of the RH gene locus explains mechanisms for generating RHD/RHCE hybrid alleles and the RHD deletion. Specific detection of the RHD negative genotype is now possible. The utility of the RHD PCR is limited by the incomplete knowledge of presumably rare RHD positive alleles in D negative. 1068 serologically RhD-negative samples were checked by PCR-SSP for the presence of RHD specific nucleotide sequences. 48 Samples were positive and were then assigned to specific PCR patterns or distinct RHD alleles. Seven PCR patterns were identified, three of which were not described previously, and four new RHD alleles that were RhD-negative because of nonsense or splice mutations. Another three new haplotypes represented a Del phenotype. Three samples were mislabeled weak D or partial D. The sensitivity of current RHD PCR methods exceeded routine serology. As the molecular background of D-negative alleles causing false-positive RHD PCR in whites is more heterogeneous than anticipated, improvements in test specificity will critically depend on detecting RhD-negative RHD positive alleles.
A resin composition for forming an optical waveguide brings together excellent bending resistance, a low refractive index, and low tackiness suitable for a roll-to-roll (R-to-R) process as a material for forming an optical waveguide, in particular, a material for forming a clad layer. The resin composition for forming an optical waveguide to be used in formation of an optical waveguide includes a polyvinyl acetal compound having a structural unit represented by the following general formula (1) as a main component: in the formula (1), R represents an alkyl group having 1 to 3 carbon atoms, and k, m, and n represent ratios of respective repeating units in a main chain and each represent an integer of 1 or more.
The present invention relates to a photosensitive composition including an acrylate-based compound having an adamantyl structure. It is possible to manufacture an organic thin film that is easily stripped without decreasing the strength of the thin film by using the photosensitive composition.
A resist composition including a base component (A) which exhibits changed solubility in an alkali developing solution under action of acid and an acid-generator component (B) which generates acid upon exposure, the acid-generator component (B) including an acid generator (B1) consisting of a compound represented by general formula (b1-1) shown below: wherein RX represents a hydrocarbon group which may have a substituent exclusive of a nitrogen atom; each of Q2 and Q3 independently represents a single bond or a divalent linkage group; Y1 represents an alkylene group or fluorinated alkyl group of 1 to 4 carbon atoms; and Z+ represents an organic cation exclusive of an ion represented by general formula (w-1).
Provided is a two-component developer containing: a magnetic carrier obtained by coating a magnetic core with a resin; and toner, in which: the magnetic core contains at least a ferrite component and at least one kind of an oxide selected from the group consisting of SiO2 and Al2O3; the content of the oxide is 4.0 mass % or more and 40.0 mass % or less with respect to the magnetic core; the magnetic core has a specific resistance of 5.0×104 Ω·cm or more and 5.0×108 Ω·cm or less at the time of the application of 1,000 V/cm; the magnetic carrier has an intensity of magnetization in 79.6 kA/m of 40.0 Am2/kg or more and 65.0 Am2/kg or less, and a residual magnetization after the application of an external magnetic field of 79.6 kA/m of 3.0 Am2/kg or less; and the toner has a weight-average particle diameter (D4) of 3.0 μm or more and 10.0 μm or less and an average circularity of 0.940 or more and 0.990 or less.
Provided is fuel cell system capable of eliminating any failure caused by freezing of a discharge valve during a low temperature while preventing an increase in size of the system. A fuel cell system is provided, the system including: a fuel cell; a diluter that dilutes a fuel-off gas discharged from the fuel cell with an oxidant-off gas discharged from the fuel cell to discharge the resulting gas to the outside; a fuel-off gas flow path that connects the fuel cell and the diluter; and a discharge valve that is provided to the fuel-off gas flow path to discharge a fuel-off gas flowing through the fuel-off gas flow path to the outside during a valve opening operation. In the fuel cell system, the discharge valve is integrally attached to the diluter.
The present disclosure discloses an organosilicon polymer, a solid electrolyte comprising the organosilicon polymer, and a corresponding solid-state lithium-ion battery. The organosilicon polymer of the present disclosure is a polymer compound comprising both an inorganic backbone-chain structure and an organic side-chain structure, and has the characteristics of both the organic polymer and the inorganic polymer as well as many unique properties. Therefore, the solid electrolyte formed by the organosilicon polymer and the solid-state lithium-ion battery thereof have many good characteristics including a good lithium-ion-conduction capability, better resistance to high temperatures, a wider range of operating temperatures, and better thermal stability.
Disclosed is a positive active material for a lithium secondary battery. The positive active material includes a lithium molybdenum oxide having an X-ray diffraction (XRD) pattern with peaks at 11.5±2°, 21±2°, 38±2°, and 64±2° 2-theta (2θ) and represented by Formula 1: LixMoO3, where 1
A method for extracting ions from an active material for use in a battery electrode includes mixing the active material and an activating compound to form a mixture. The mixture is annealed such that an amount of ions is extracted from the active material, an amount of oxygen is liberated from the active material, and an activated active material is formed. Embodiments of the invention include the activated active material, the electrode, and the primary and secondary batteries formed from such activated active materials.
A battery charger includes a battery attachment section configured to have a rechargeable battery releasably attached thereto. The battery attachment section includes a flat attachment surface having a width corresponding to a width of a bottom surface of a case of the battery to be charged and a length greater than a length of the bottom surface of the case of the battery to be charged; a plurality of locking hooks provided on the attachment surface; a charger terminal configured to contact a terminal of the battery to be charged, the charger terminal including a plurality of plate-shaped contact pieces configured to be inserted into engaging grooves of the battery to be charged; and an attachment projection adjacent to the attachment surface and configured to secure the battery to the charger.
A battery pack is provided. The battery pack has a base plate and a peripheral side wall extending upwardly from the base plate. The peripheral side wall has first and second side portions disposed at first and second ends, respectively, of the base plate. The battery pack further includes a plurality of battery modules disposed on the base plate between the first and second ends of the base plate along a longitudinal axis of the base plate. The battery pack further includes a first mounting bracket coupled to the first side portion of the peripheral side wall. The battery pack further includes a second mounting bracket having a plate portion, an extension portion extending outwardly from the plate portion, and an elastomeric member disposed on the extension portion.
A battery pack having at least one battery with two electrical contacts in which a parallel circuit comprising a first and a second resistor is arranged between a first contact and a first pole, the first resistor switches off at a first temperature, the second resistor switches off at a second temperature, the first temperature is higher than the second temperature, and the first resistor has a higher current carrying capability than the second resistor. The circuit serves as fuse protection for the battery against overheating both when the battery is charging and when the battery is discharging.
Disclosed is an apparatus and method for preventing deformation of a plastic battery pack case for a vehicle, in which the side of the battery pack case is subjected to reverse deformation to absorb the deformation occurring after compression molding and to ensure the dimensions of a mounting portion of various components including battery packs, thereby ensuring an internal space of the battery pack case. To this end, the present invention provides an apparatus for preventing deformation of a plastic battery pack case for a vehicle, the apparatus including: a base having a case insertion space; a fixing portion for fixing a battery pack case inserted into the case insertion space; and a deformation producing portion inserted into the battery pack case and preventing the case from being deformed by pressing the inside of the case to be reversely deformed in the lateral direction.
A battery storing device may include: a case member having a positive terminal and a negative terminal and configured to store a battery therein; a positive pole coil spring in contact with a positive electrode of the battery; a negative pole coil spring in contact with a negative electrode of the battery; and a first support comprising a sidewall support section having an elastic force that is able to fix the battery while absorbing a size difference of the battery allowed according to a standard, and configured to support a sidewall of the battery.
A vehicle battery pack container is provided. The container includes a base member, a peripheral wall coupled to the base member, and a cover member coupled to the peripheral wall. The container further includes a venting device having a venting housing and a flow diverter member disposed within an interior region of the venting housing. The venting housing is coupled to the base member and is in fluid communication with an aperture in the base member. The venting housing has a tubular portion and a first end portion having a plurality of apertures extending therethrough. The flow diverter member has a central shaft, a first flow diverter plate, and a second flow diverter plate.
A light-emitting element material including an ionic iridium complex in which a 2,6-bis(2-picolinyl)pyridine structure is coordinated to iridium is provided. Alternatively, a light-emitting element material including an ionic iridium complex represented by the following structural formula (1) is provided. In addition, a light-emitting element including the light-emitting element material is provided.
A method for passivating a metallic surface, by treating the surface with a basic aqueous composition comprising one polymer comprising acidic groups, a cationic crosslinker and a volatile basic compound, allows a durable passivation of fragile metal surfaces.
Disclosed herein is a hard film containing boron and carbon, wherein the hard film includes a plurality of concave portions and a plurality of convex portions formed on a surface of the hard film, and wherein carbon concentration in the concave portion is higher than that in the convex portion and boron concentration in the convex portion is higher than that in the concave portion. Further, disclosed herein is a method of manufacturing a sliding part having a hard film containing boron and carbon disposed over a substrate; wherein the hard film is manufactured by using at least one of an unbalanced magnetron sputtering method or a high power pulsed magnetron sputtering method, both sputtering methods using a target containing at least one of elements of silicon, chromium, titanium, and tungsten and a boron carbide target.
A core-pin assembly composed of a primary core-pin and at least one secondary core-pin. The primary core-pin has a primary core-pin body defining at least one element for coupling with a mating end of at least one secondary core-pin. The secondary core-pin has a mating end and a secondary core-pin body. The mating end is configured to fit with the element defined in the primary core-pin body such that the primary core-pin and the secondary core-pin(s) reversibly join together to form a branching structure. The assembly may further include at least one tertiary core-pin and the secondary core-pin body may define at least one element for coupling with a mating end of at least one tertiary core-pin. The mating end of the tertiary core pin is configured to fit with the secondary core-pin body such that the primary core-pin, secondary and tertiary core-pin(s) reversibly join together forming a branching structure.
An apparatus for filling joints in precast concrete structures includes a core that has exceptionally low creep and conforms to ASTM D 1752 made of controlled particle size composites of recycled cellular rubber and plastic materials in the form of a rectangular slab. Holes are drilled through a central area and countersink recesses are formed around the holes. An outer coating of a thermoplastic polyurethane/polyurea elastomer system of a thickness of 0.075 inch covers the slab and countersink recesses. The coated core is abrasion and UV resistant while having the creep characteristics needed to make a dam expansion joint filler.
The adhesive film includes a film-like adhesive layer, a light release separator and a heavy release separator that are laminated on either side of the adhesive layer, and a carrier film further laminated on the heavy release separator. The outer edges of the light release separator and the carrier film forming the outer layer extend outward beyond the outer edge of the adhesive layer and the heavy release separator forming the inner layer. The outer edge sections of the adhesive layer are thereby protected. The outer edge section of the carrier film is gripped and released first, after which the outer edge section of the light release separator is gripped and released, and finally the heavy release separator is released, thereby allowing each separator and the carrier film to be reliably and easily released in the prescribed order.
The present disclosure relates to methods and systems for synthesis of bridged-hydropentacene, hydroanthracene and hydrotetracene from the precursor compounds pentacene derivatives, tetracene derivatives, and anthracene derivatives. The invention further relates to methods and systems for forming thin films for use in electrically conductive assemblies, such as semiconductors or photovoltaic devices.
The present invention aims to provide techniques for preparing matte coated printing papers having high opacity and brightness as well as improved brightness variation at low basis weight with good runnability.According to the present invention, a process for preparing a matte coated printing paper having a basis weight of 60 to 90 g/m2, a brightness of 75% or more, and an opacity of 95% or more is provided, comprising applying a coating solution containing calcium carbonate by curtain coating on a base paper having a brightness of 45 to 70% made from a raw material pulp containing a total of 50% or more of deinked pulp and/or mechanical pulp.
A method of dispensing adhesive onto a stretched elastic strand includes applying a first volume of adhesive onto a first portion of the elastic strand, applying a second volume of adhesive onto a second portion of the elastic strand, and applying a third volume of adhesive onto a third portion of the elastic strand. The second volume is less than the first and third volumes. When the elastic strand is adhered to a substrate to form a personal disposable hygiene product, the first and third portions of the elastic strand define opposing ends of the elastic strand, which are adhered with a larger amount of adhesive to resist creep at the opposing ends. The reduction of adhesive in the second or central portion between the opposing ends significantly reduces the adhesive add on in the personal disposable hygiene product.
A silver salt-containing layer containing a silver salt and provided on a support is exposed and developed to form a metal silver portion and a light-transmitting portion, and then the metal silver portion is further subjected to physical development and/or plating to form a conductive metal portion consisting of the metal silver portion carrying conductive metal particles. A method for producing a light-transmitting electromagnetic wave-shielding film which enables production of an electromagnetic wave-shielding material simultaneously having high EMI-shielding property and high transparency in a fine line pattern and also enables mass production of such films at a low cost, and a light-transmitting electromagnetic wave-shielding film obtained by the production method and free from the problem of moire are provided.
A process for preparing an extract of Momordica charantia, including: a) preparing crude juice; b) filtering to obtain filtered juice; c) modifying pH; d) allowing the pH modified juice to stabilize; e) neutralizing the stabilized juice; f) allowing the neutralized juice to stand for 20-30 minutes; g) rechecking the pH level; and h) drying the juice to obtain the extract. The process said above is simple, cost effective, which does not employ any harmful organic solvents and which enhances the potency of the constituents. A simple and potent formulation showing anti-diabetic activity comprising active constituents of Momordica charantia is also provided.
The present invention provides methods of administering a Dendrobium polyphenol in an amount effective to lower blood sugar, treat hepatic disease, obesity or diabetes. Exemplary hepatic disease includes fibrosis, fatty liver and hepatitis. Moreover, the Dendrobium polyphenol is extracted from the plants of the genus Dendrobium.
Bioactive agrichemical concentrates and compositions having improved bioactivity comprising combinations of acid solutions and conventional bioactive agrichemical actives or formulations.
The present invention relates to the use of pharmaceutically acceptable zinc salts, preferably water soluble zinc salts alone or optionally, in combination with one or more of a protein pump inhibitor (PPI), H2 blocker, anti-H. pylori antibiotic/antimicrobial, cytoprotective agent or a combination agent as otherwise described herein for providing fast action with optional long duration effect in reducing gastric acid secretion, raising the pH of the stomach during resting phase as well as decreasing the duration of stomach acid release during a secretagogue phase and for treating conditions including gastroesophageal reflux disease (GERD), non-erosive reflux disease (NERD), Zollinger-Ellison syndrome (ZE disease), ulcer disease, and gastric cancer, as well as preventing or reducing the likelihood of ulcer disease. In addition, the present methods are useful for treating patients who are non-responsive to proton pump inhibitors (PPI) and as an alternative to traditional therapies or conditions which are caused by rapid and complete inhibition of secretagogue induced acid secretion. The present invention also relates to the use of one or more water soluble zinc salts, administered in combination with a therapeutic compound or agent (second therapeutic agent) which may be delivered orally with enhanced bioavailability (compared to compounds which are administered in the absence of water soluble zinc salts) or other favorable benefits. In addition, therapeutic agents which exhibit sensitivity to low pH may be advantageously orally administered in combination with an effective amount of at least one water soluble zinc salt. Compositions according to the present invention exhibit greater bioavailability of the active agent when formulated in combination with a water soluble zinc salt in oral dosage form than when administered with the water soluble zinc salt.
This invention relates to biocompatible, biodegradable thermoplastic polyurethane or polyurethane/ureas comprising isocyanate, polyol and a conventional chain extender and/or a chain extender having a hydrolysable linking group and their use in tissue engineering and repair applications, particularly as stents and stent coating.
The instant invention is drawn to a hepatocyte targeted composition comprising insulin associated with a lipid construct comprising an amphipathic lipid and an extended amphipathic lipid that targets the construct to a receptor displayed by an hepatocyte. The composition can comprise a mixture of free insulin and insulin associated with the complex. The composition can be modified to protect insulin and the complex from degradation. The invention also includes methods for the manufacture of the composition and loading insulin into the composition and recycling various components of the composition. Methods of treating individuals inflicted with diabetes.
A transdermal delivery system is provided where the drug delivery rates, onset and profiles of at least one active agent are controlled by selectively manipulating the monomeric make up of an acrylic-based polymer in the transdermal drug delivery system. The drug carrier composition may be comprised of (a) one or more acrylic-based polymers having one or more different monomers selected from the group consisting of hard and soft monomers; (b) one or more silicone-based polymers; and (c) one or more active agents where the device provides a desired solubility for the active agent and controls drug delivery rates, onset and profiles of at least one active agent.
Articles comprising one or more calcium salts are provided. The articles can contain one or more calcium salts in an amount effective to reduce the production of TSST-1 by at least about 50% when measured by the Shake Flask Method. In certain embodiments, the one or more calcium salts can be substantially non-lethal to Staphylococcus aureus when measured by the Shake Flask Method, and/or to Lactobacillus crispatus, Lactobacillus gasseri, and/or Lactobacillus iners when measured by the Maximum Tolerated Dose Test.
Biostable, multipurpose, microbicidal intravaginal devices in the form of rings, ringed-meshes, sponges, or diaphragms for use by women and condoms for use by male partners are provided, wherein each of the devices contains a drug effective in treating a particular vaginal infection, while further exhibiting at least one additional function selected from the group dealing with non-hormonal contraception, management of sexually transmitted diseases, viral infections, and retroviral infections as well as the treatment of cervical cancer.
A method and device for local delivery of water-soluble or water-insoluble therapeutic agents to the surface of a normal or diseased body lumen is disclosed. An expandable structure of a medical disposable device, such as a balloon of a balloon catheter, is coated with an amphiphilic polymer coating comprising a therapeutic agent and an amphiphilic polymer or co-polymer. The medical disposable device is inserted into a body lumen, and expanded to contact the amphiphilic polymer coating against the body lumen. The total solubility of the polymer or co-polymer in vivo prevents any embolic hazard associated with the amphiphilic polymer coating.
An apparatus (or a biogenerator) is disclosed which utilizes the electrochemical polarization of epithelial cells to generate electricity. The apparatus employs living cells to convert chemical energy into electricity. The biogenerator is capable of supplying electricity to other devices continuously for extended periods of time. Because the apparatus may be made sufficiently small for implantation into the body of an animal or a human, such an apparatus is particularly useful for powering devices that require implantation into the host body.
The present invention relates to a drug carrier composition comprising i) one or more biodegradable hydrating ceramics ii) one or more expandable agents, and iii) sorbed aqueous medium which in solid form has a ruptured structure. The function of the expandable agent is to create a ruptured structure in the solidified composition, either a foam-like structure or a disintegrated structure where it is split into a large number of parts, particles, units, granules or pieces, so as to obtain an enlarged apparent surface area that is exposed to degradation or erosion upon administration. Suitable substances to obtain this surface enlarging effect are gas-forming agents or swelling agents, gelling agents or disintegrants, here referred to as expandable agents. The expandable agents may be bioresorbable or non-bioresorbable.
The invention is directed toward porous composites for application to a bone defect site to promote new bone growth. The inventive porous composites comprise a biocompatible polymer and a plurality of particles of bone-derived material, inorganic material, bone substitute material or composite material. In certain embodiments, the porous composites are prepared using a method that includes a supercritical fluid (e.g., supercritical carbon dioxide) treatment. The invention also discloses methods of using these composites as bone void fillers.
A polymeric composition capable of releasing nitric oxide and modulating biological responses comprises a biocompatible polymer and S-nitrosated thiol bonded to the biocompatible polymer. The polymeric composition can have a thiol conversion of at least 40%. The polymeric composition can also have a nitric oxide recovery of at least 40% when under thermal decomposition conditions.
Disclosed herein are mesocapsules that include agriculturally active ingredients. These mesocapsules are comprised of a polyurea shell and include hydrophilic groups on their surfaces and have a volume-average diameter of about 500 nm or less and some of them have a volume-average diameter on the order of about 300 nm or less. These mesocapsules are suited for delivering active ingredients that are not very soluble in water. Methods for making these mesocapsules include interfacial polycondensation reactions carried out in the presence of surfactants and other methods in which all or most of the surfactant is replaced by adding amino acids to the aqueous phase of the interfacial reaction mixture before forming the final emulsion.
In the present invention, the applicants describe methods and compositions of treating damaged cardiovascular elements and cardiovascular conditions including hypotension, atherosclerotic lesions, vulnerable plaque, and acute myocardial infarct. The applicants demonstrate the ability of a biomembrane sealing agent to accumulate on the walls of damaged blood vessels and help improving mean arterial pressure following tissue injury. The applicants describe the use of formulations comprising at least one biomembrane sealing agent and one bioactive agent for prophylactic treatment such as they could be administered concurrently to an invasive therapeutic intervention or after the insult (i.e. post-injury or post-surgery). Alternatively, these methods and compositions could be used to reduce the severity of cardiovascular diseases after onset.
The present invention relates to oncolytic adenoviruses having therapeutic applications. Recombinant chimeric adenoviruses, and methods to produce them are provided. The chimeric adenoviruses of the invention comprise nucleic acid sequences derived from adenoviral serotypes classified within the subgroups B through F and demonstrate an enhanced therapeutic index.
The invention relates to methods for controlling the glycosylation of a RAGE fusion protein. The invention also relates to compositions comprising an amount of a RAGE fusion protein where at least 0.5% of the amount of the RAGE fusion protein is aglycosylated and wherein no more than 53.2% of the amount of the RAGE fusion protein is aglycosylated.
The invention provides improved agents and methods for treatment of diseases associated with synucleinopathic diseases, including Lewy bodies of alpha-synuclein in the brain of a patient. Such methods entail administering agents that induce a beneficial immunogenic response against the Lewy body. The methods are particularly useful for prophylactic and therapeutic treatment of Parkinson's disease.
The present invention provides methods of preparing an antibody- or antibody fragment-targeted cationic immunoliposome or polymer complex comprising (a) preparing an antibody or antibody fragment; (b) mixing said antibody or antibody fragment with a cationic liposome to form a cationic immunoliposome or with a cationic polymer to form a polyplex; and (c) mixing said cationic immunoliposome or said polyplex with a therapeutic or diagnostic agent to form said antibody- or antibody fragment-targeted cationic immunoliposome or polymer complex. The present invention also provides cationic immunoliposome or polymer complexes produced by such methods and compositions comprising such complexes. The present invention also provides methods for treating various diseases and disorders, including cancers, by administering the complexes and compositions of the invention to a patient.
The described invention provides pharmaceutical compositions for treating an infarct area injury and methods of treating or repairing the infarct area injury in a revascularized subject in the aftermath of an acute myocardial infarction resulting from a natural disease process by administering to the subject parenterally through a catheter a sterile pharmaceutical composition containing a therapeutically effective amount of a nonexpanded sterile isolated chemotactic hematopoietic stem cell product as a first therapeutic agent and optionally a therapeutically effective amount of at least one compatible second therapeutic agent. The infarct area-improving amount of the sterile isolated chemotactic hematopoietic stem cell product comprises an enriched population of isolated autologous CD34+ cells containing a subpopulation of potent cells expressing CXCR-4 and having CXCR-4-mediated chemotactic activity such that the enriched population of isolated autologous CD34+ hematopoietic stem cells provides at least 0.5×106 potent CD34+ cells expressing CXCR-4 and having CXCR-4 mediated chemotactic activity.
New pyridin-2(1H)-one derivatives having the chemical structure of formula (I) are disclosed; as well as process for their preparation, pharmaceutical compositions comprising them and their use in therapy as inhibitors of Janus Kinases (JAK).
The invention relates to a high SPF sunscreen composition. There is a problem of achieving high SPF while keeping the total amount of sunscreens in the compositions relatively low. It is desirable, that the enhanced SPF benefit could be achieved through synergistic interaction of commonly used ingredients, thereby the present applicants have been working on solving this problem and have surprisingly found that cosmetic compositions comprising dibenzoylmethane or its derivative in combination with an oil soluble UV-B sunscreen when incorporated in a sunscreen composition along with a non-ionic surfactant of a select class meeting certain HLB requirements, provide the enhanced SPF benefits when applied on the substrate of interest.
8-Hydroxy-quinoline derivatives and 8-ethers, 8-esters, 8-carbonates, 8-acyloxymethyl, 8-phosphates, (phosphoryloxy)methyl, and 8-carbamates derivatives thereof are described that exhibit iron chelation, neuroprotective, neurorestorative, apoptotic and/or selective MAO-AB inhibitory activities.
In one aspect, the invention relates to a method for identifying a drug candidate with activity as a neuroprotective agent. The method includes determining whether a compound reduces ATF4 activity; and identifying the compound that reduces ATF4 activity as a drug candidate.
An object the invention is to provide a phosphorus pentafluoride producing process wherein phosphorus pentafluoride is separated/extracted from a pentavalent phosphorus compound or a solution thereof, or a composition obtained by allowing the pentavalent phosphorus compound or the solution thereof to react with hydrogen fluoride, thereby producing phosphorus pentafluoride; and a phosphate hexafluoride producing process wherein the resultant phosphorus pentafluoride is used as raw material to produce a phosphate hexafluoride high in purity. The present invention relates to a process for producing phosphorus pentafluoride, wherein a carrier gas is brought into contact with either of the following one: a pentavalent phosphorus compound, a solution thereof, or a solution in which a composition obtained by allowing the pentavalent phosphorus compound or the solution thereof to react with hydrogen fluoride is dissolved, thereby a phosphorus pentafluoride is extracted into the career gas.
A method for extending the service life of a Collective Protection (CP) filter includes: providing at least one CP filter comprising a filter bed; and passing an airstream through a guard bed configured to protect the filter bed by removing one or more of airborne contaminants and battlefield contaminants. An apparatus for extending the service life of a CP filter includes: a CP filter comprising a filter bed; and a guard bed configured to protect the filter bed by removing one or more of airborne contaminants and battlefield contaminants.
Described are catalyst compositions, catalytic articles, exhaust gas treatment systems and methods that utilize the catalytic articles. The catalyst composition comprises a washcoat including a zeolite, refractory metal oxide support particles, and a platinum group metal supported on the refractory metal oxide support particles. Greater than 90% of the refractory metal oxide particles supporting PGM have a particle size greater than 1 μm and a d50 less than 40 microns.
A high-throughput system for processing biological material that comprises: a tray that supports a functionally-closed fluid path subsystem comprising, a vessel for containing and enabling the biological material to separate into two or more distinct submaterials; one or more receptacles to receive one or more of the submaterials from the vessel; a filtration device; a conduit through which one or more submaterials are transported between at least the vessel and the filtration device; and a first engagement structure; a processing unit comprising, a pumping device for moving one or more of the submaterials between at least the vessel and the filtration device via the conduit; a second engagement structure corresponding to the first engagement structure; a locking mechanism for at least temporarily holding the tray in a fixed position relative to the processing unit; a control device that automatically starts and stops the pumping device in response to one or more commands.
The present application provides apparatus and methods for determining the density of a fluid sample. In particular, it provides a sensor device which can be loaded with a fluid sample such as blood, and which further comprises at least one oscillating beam member or resonator. Exposure of the blood sample to clotting agents allows a clotting reaction to commence. The device allows the density of the sample fluid to be monitored with reference to the oscillation of the vibrating beam member, thus allowing the monitoring of the clotting of the fluid sample.
A system and method are disclosed in which particles sorted by a flow cytometer may be deposited directly into a deposition layer formed on the surface of an optical disc, and information regarding measurements made of the particle, as well as the storage location of the particle, can be written to the recording layer of the optical disc.
The invention provides a device and a method for flow cytometric fractionation of particles contained in a fluid stream, wherein sections of the fluid stream, especially droplets if the fluid stream is a droplet stream, are irradiated with a laser. The laser disposed for the irradiation of the sections of the fluid stream can have a wavelength which is absorbed by the fluid and can have a sufficient radiation duration and radiation intensity to deflect sections of the fluid stream.
A method of forming a component (30) by isostatic pressing, the method comprising: providing a canister (4) suitable for isostatic pressing, the canister comprising first and second membranes (14, 16) which, in use, are disposed within the canister (4); the first and second membranes (14, 16) defining a component cavity (24) disposed between the first and second membranes (14, 16), a first tool cavity (26) disposed between the first membrane (14) and an adjacent wall (10) of the canister (4), and a second tool cavity (28) disposed between the second membrane (16) and another adjacent wall (12) of the canister (4); filling the component cavity (24) with the component powder for forming the component (30); filling the first and second tool cavities (26, 28) with a second tool powder; and isostatically pressing the canister (4) to form the component (30).
Devices and methods for high-throughput manufacture of concentrically layered nanoscale and microscale fibers by electrospinning are disclosed. The devices include a hollow tube having a lengthwise slit through which a core material can flow, and can be configured to permit introduction of sheath material at multiple sites of Taylor cone formation formation.
A liquid container includes a brim forming a mouth opening into a product receiving chamber formed in a cup. A lid is coupled to the rim to close the mouth of the cup.
In accordance with this invention a binder composition for treating particulate material to form a solid aggregate matrix is prepared by providing a urea formaldehyde precondensate; a polar solvent; additional urea; an acid or salt thereof, the acid or salt thereof being selected such as to render the pH of the binder composition to a value from 2.0 to 5.3; providing a sugar; providing a binding promoter for enhancing the binding between the binder composition and the particulate material; and mixing the above so as to form a binder composition. The binder composition is mixed with particulate material and allowed to set into a solid aggregate matrix over a period of longer than 30 minutes from being mixed with the said particulate material.
The invention relates to a method for producing implants and components by direct shaping. The method includes the steps of producing a mold for the implants or components to be produced, making allowances for changes in geometry occurring during after-treatment after the implants or components are removed from the mold, and, providing partial areas of the mold with a structured surface for transferring this structure to the surfaces of the implants or components. In the method, raw material is introduced into the mold and, after remaining in the mold for a certain period of time, the hardened raw material is then removed from the mold to allow the implants or components to take on the structured surface of the mold as well as its geometry. The demolded implants or components are finally subjected to any after-treatment that may be necessary.
This disclosure relates to a method of preparing polyamide particles. The method include spray drying a solution containing a polyamide to form polyamide particles having an average diameter of between about 0.5 μm and about 10 μm and at least about 85% of the polyamide particles having a diameter distribution of no more than about 1.5 μm.
A method for making optical connections with optical waveguides includes mounting the optical waveguides or a device comprising the optical waveguides, on a component carrier. A partial region of the optical waveguides is embedded in a volume of resist material. Positions of the optical waveguides to be connected are detected with reference to a coordinate system using a measuring system. Favorable, three-dimensional geometries are determined for optical waveguide structures for connecting the optical waveguides to each other at predetermined connecting locations and the optical waveguide structure geometries are converted to a machine-readable dataset. The optical waveguide geometries in the volume of the resist material are three-dimensionally structured using a direct-writing lithography device operating on the basis of the machine-readable dataset. The structured resist material is treated using physical or chemical methods to form at least one optical waveguide structure having ends connected to predetermined connecting locations of the optical waveguides.
Described herein are compounds generally comprising an indeno[2′,3′:3,4]naptho[1,2-b]pyran structure. Such compounds may be useful for their photochromic properties, and be used in certain photochromic compositions. Such compositions may further comprise other photochromic compositions and/or materials. Additionally, such compounds and/or compositions may be suitable for preparing certain photochromic articles. Also described herein are methods for preparing certain photochromic compounds, compositions, and articles.
An electron emission source includes nano-sized acicular materials and a cracked portion formed in at least one portion of the electron emission source. The acicular materials are exposed between inner walls of the cracked portion. A method for preparing the electron emission source, a field emission device including the electron emission source, and a composition for forming the electron emission source are also provided in the present invention.
A feedstock for injection molding includes a ceramic filler that is sinterable to produce a ceramic with a positive temperature coefficient of electrical resistance, a matrix for binding the ceramic filler, the matrix having a melting point lower than a melting point of the ceramic filler, and metallic impurities. A content of the metallic impurities in the feedstock is lower than 10 ppm.
A process to convert light hydrocarbons such as natural gas to a liquid or liquids. Vacuum pressure swing adsorption (VPSA) is used to produce a stream of relatively high purity oxygen. The relatively high purity oxygen is reacted with light hydrocarbons and steam in an autothermal reformer in order to produce synthesis gas. The synthesis gas is thereafter converted to a hydrocarbon liquid or liquids via a Fischer Tropsch or related reaction.
Disclosed is a halogen silicate luminescent material having a chemical structural formula of (N1−a−bEuaMnb)10Si6O21Cl2 with xM nanoparticles, and the preparation method thereof, where M is at least one of Ag, Au, Pt and Pd, N is an alkaline earth metal and specifically at least one of Mg, Ca, Sr and Ba, 0
Disclosed is a pressurized hollow fiber membrane module that exhibits improved durability without deterioration in packing density and permeation flux. The pressurized hollow fiber membrane module includes a composite hollow fiber membrane comprising a tubular braid woven by yarns and a polymer film on the outer surface of the tubular braid. At least one of the yarns comprises a small-fineness filament and a medium-fineness filament. The small-fineness filament comprises first monofilaments having a fineness of 0.01 to 0.4 denier, the medium-fineness filament comprises second monofilaments having a fineness higher than 0.4 and lower than 3, and a ratio of thickness of the tubular braid to outer diameter thereof is 15 to 35%.
An apparatus for providing magnetic fluid treatment is described. The apparatus includes a serial coupling of conduit segments forming a conduit. At least two of the conduit segments are constructed of a magnetically conductive material and at least one of the conduit segments is constructed of a non-magnetically conductive material and positioned in between the conduit segments constructed of the magnetically conductive material to establish a non-magnetically conductive region. At least one electrical conductor encircles at least a section of the outer surface of the serial coupling of conduit segments. Energizing the electrical conductor establishes a magnetic field having lines of flux directed along a flow path of the conduit and concentrated in the non-magnetically conductive region of the conduit.
A method and device for the cleaning of spiral wound membranes. In the device two or more spiral wound membranes are included in series in pressure tubes. The membranes are cleaned by longitudinal rinsing with water, in which a well-dissolvable gas has been dissolved. In the device for the purification of an aqueous fluid with spiral wound membranes, the membranes can be longitudinal rinsed with water, in which a well-dissolvable gas has been dissolved. As gas that is well-dissolvable preferably CO2 gas or a mixture of gasses is used.
An electrochemical test sensor for detecting the concentration of an analyte in a fluid sample. The electrochemical test sensor includes a housing that has a first end and a second opposing end. The housing includes an opening at the first end to receive a fluid test sample. An electrode assembly includes a substrate, a working electrode, a counter electrode and a reagent. The substrate has a first surface and an opposing second surface. The working electrode is disposed on the first surface of the substrate, and the counter electrode is disposed on the second surface of the substrate. The electrode assembly is positioned within the housing to define a reaction channel. The electrochemical test sensor may be used with a removable lancet mechanism or integrated within a lancet mechanism to form one integral unit.
An electrode assembly for capillary electrophoresis (CE) comprises a manifold (310), a connector (305) a sheath (300), and a seal (325). A capillary tube (100) passes through the manifold, the connector, the sheath, and the seal, stopping just beyond the end of the sheath. The sheath is fillable with water (330) or another fluid that cools the capillary tube in the vicinity of the electrode, thereby preventing degradation of a sample due to heat. The sheath may be metal or plastic with a metal sleeve electrode on its exterior. The sheath is sufficiently strong to penetrate a rubber or other pierceable cap on a vial. The manifold and connector incorporate an air path (605, 312, 307) so that when the electrode is fully inserted into a vial, the contents (650) of the vial are at atmospheric pressure (or another applied pressure or vacuum).
A method for reducing the coking time in the oven area near the door or end wall and for improving coke quality and situation of emissions by compensating for radiation losses through coke oven chamber doors and end walls is described. This compensation is accomplished by varying the height of the coal cake in the environment of the frontal coke oven chamber doors. The variation is achieved both by increasing or decreasing the coal cake over part of the length or over the entire length of the coke oven chamber door. The reduction in the height of the coal cake can be generated by omission of coal or coal compacts, the increase in height can be accomplished by stacking of coal and pressing or adding of coal compacts, with it also being envisaged to omit the pressing cycle so as to obtain a recess with a lower coal cake density which also has less heat radiation.
The present invention relates to a method of producing an edging-fold bond. For this purpose use is made more particularly of high-viscosity adhesives. The method features reduced bubble formation within the edging fold and also within the sealant (where present) that seals the edging-fold seam. More particularly the adhesive comprises spacers which further reinforce this effect.
Methods for manufacturing laminated membranes for MEAs, such methods comprising (i) providing a substrate, a catalyst ink fluid, and a first membrane fluid; (ii) providing a second membrane fluid; (iii) simultaneously coating the catalyst ink fluid onto the substrate, the first membrane fluid onto the catalyst ink fluid, and the second membrane fluid onto the first membrane fluid; and (iv) applying a reinforcement layer (such as ePTFE) and allowing for full imbibement. The second membrane fluid (i) consists of alcohol or (ii) is an alcohol-rich fluid comprising polymer electrolyte.
The pyrotechnic smoke kit for generating a smoke screen comprises a mixture of a light-metal powder as the metallic reduction agent; potassium nitrate and, optionally, potassium perchlorate as the main oxidation agent; at least one carbonate as an additional auxiliary oxidation agent; substances splitting off nitrogen as combustion moderators and at least one sublimable and/or evaporable non-toxic smoke-forming substance. A stabilizer from the group of aliphatic and/or aromatic dicarboxylic acids is added to the mixture of the smoke kit to stabilize the smoke kit. Due to this, the formation of gaseous ammonia in the smoke kit can be prevented.
A method for manufacturing an Ni base alloy pipe stock comprises piercing and rolling a billet by use of Mannesmann piercing and rolling mill. The pipe stock has controlled amounts of C, Si, Mn, P, S, Cr, Ni, Mo, W, Cu, Al, N, with the balance being Fe. With the method, the following equations are satisfied, wherein values of TGBm, Psr and Pσ represented by the following equations (1) to (3) being not more than 1300, not more than 200 and not less than 0, respectively TGBm=1380−5000P−100S−4400C (1), PsrNi+10(Mo+0.5W)+100N (2), Pσ=(Ni−50)+10(N−0.1)−2(Cr−25)−5(Mo+0.5W−6)+12 (3), wherein each element symbol in the equations represents mass % of the element concerned.
A low alloy steel ingot contains from 0.15 to 0.30% of C, from 0.03 to 0.2% of Si, from 0.5 to 2.0% of Mn, from 0.1 to 1.3% of Ni, from 1.5 to 3.5% of Cr, from 0.1 to 1.0% of Mo, and more than 0.15 to 0.35% of V, and optionally Ni, with a balance being Fe and unavoidable impurities. Performing quality heat treatment including a quenching step and a tempering step to the low alloy steel ingot to obtain a material, which has a grain size number of from 3 to 7 and is free from pro-eutectoid ferrite in a metallographic structure thereof, and which has a tensile strength of from 760 to 860 MPa and a fracture appearance transition temperature of not higher than 40° C.
A composition to decommission firearms is presented. The composition comprises a monomer, a quantity of calcium chloride; and sulfur-containing compound. The sulfur containing compound includes sodium persulfate and/or sodium thiosulfate.
A manufacturing method for a composite steel part including manufacturing a first steel part by preparing an intermediate product in which an extra portion is added, and heating the intermediate product to an austenitizing temperature in a carburizing atmosphere to form a carburized layer, cooling the intermediate product at a rate less than a cooling rate at which martensitic transformation is caused and in which the intermediate product is cooled to a temperature equal to or less than a temperature at which structure transformation due to the cooling is completed, heating the intermediate product to an austenitizing range by high-density energy and thereafter cooled at a rate equal to or more than the cooling rate at which martensitic transformation is caused to form a carburized quenched portion, cutting the extra portion of the intermediate product, and welding the first steel part and the second steel part to each other.
A dishwasher having a washing compartment; an air-guiding channel to generate an airflow; and a sorption drying system to dry items to be washed. The sorption drying system has a sorption compartment with reversibly dehydratable sorption material and the sorption compartment is connected to the washing compartment by the air-guiding channel. The reversibly dehydratable sorption material in the sorption compartment is layered in form of a sorption unit that has an inlet cross-sectional area such that the substantially identical respective air volume flow value that is applied to each entry point of the inlet cross-sectional area.
Embodiments of the present disclosure include cleaning processes, closed loop cleaning machines, and methods of cleaning an article. The cleaning process includes contacting a surface of an article with a cleaning composition in a cleaning chamber, where the cleaning composition includes at least about 85 percent by weight organic solvents, based on total weight of the cleaning composition, and where at least about 5 percent by weight of the organic solvents is propylene glycol, based on total weight of the organic solvents, to clean the surface of the article, collecting the cleaning composition including contaminants, and recovering the cleaning composition via distillation, where a distillation apparatus removes the contaminants from the cleaning composition and is connected to the cleaning chamber by a process stream.
A method of fabricating a hybrid orientation substrate is described. A silicon substrate with a first orientation having a silicon layer with a second orientation directly thereon is provided, and then a stress layer is formed on the silicon layer. A trench is formed between a first portion and a second portion of the silicon layer through the stress layer and into the substrate. The first portion of the silicon layer is amorphized. A SPE process is performed to recrystallize the amorphized first portion of the silicon layer to be a recrystallized layer with the first orientation. An annealing process is performed at a temperature lower than 1200° C. to convert a surface layer of the second portion of the silicon layer to a strained layer. The trench is filled with an insulating material after the SPE process or the annealing process, and the stress layer is removed.
The method includes subjecting the pozzolans in crushed state to a high energetic mechanical processing by grinding in a grinding equipment, whereby the pozzolan particles receive mechanical impulses, and the grinding is carried out for a predetermined time resulting in a compressive strength of a 2 inch side cube of mortar having 80% Portland cement and 20% natural pozzolan in a ratio of 1:2.75 to standard sand and in addition water required to obtain a flow of the mortar according to American standard ASTM C 109, which has been properly compacted under vibration and hardened at +20° C. in sealed condition, which after 28 days is ≧75% of the compressive strength of a 2 inch side cube, treated as the cube, of a mortar having a ratio of Portland cement:sand of 1:2.75 and water corresponding to 48.5% of the weight of Portland cement.
Additives may be used to lower the set up point for bitumen thereby allowing it to be transported from place to place more easily. Additives useful for lowering the set up point of bitumen include alkylphenol formaldehyde resins and oxyalkylated alkylphenol formaldehyde resins; amines and esters; solvents; and combinations thereof.
A method and apparatus are described for swing adsorption processes. The method includes obtaining different plates, wherein the plates have gaseous openings and a utility fluid opening. Then, the gaseous openings are substantially oriented along a common axis for gaseous openings and the plates are diffusion bonded. Once diffusion bonded, the gaseous openings within the module are wash coated with an adsorbent material.
A fast gas chromatograph (GC) method and device for obtaining fast gas chromatography analysis, in which a capillary gas chromatography column is inserted into a resistively heated metal tube located mostly outside a heated oven, which serves as a heated transferline to a flexible column that enters a resistively heated metal tube from a gas chromatograph injector and exits into a gas chromatograph detector. The resistively heated metal tube of the fast GC device has an internal diameter that is over twice the external diameter of the GC column so as to enable the insertion of several capillary GC column loops. The process of column insertion into or removal from the heated tube is aided by touching it with an ultrasound vibrating device that remarkably reduces the friction during column insertion into the metal tube heater.
In a method for producing a reduced iron pellet, when a powder formed article including iron oxide and carbon is heated and reduced in a rotary hearth furnace, a formed article produced using a raw material, in which an average diameter of the iron oxide is 50 microns or less and a ratio of carbon monoxide to carbon dioxide in a reduction zone is from 0.3 to 1, is reduced at a temperature of 1400° C. or less, thereby producing a reduced iron pellet in which a metallization ratio of iron is 50 to 85% and a ratio of residual carbon is 2% or less.
A method for making a metal-based nano-composite material is disclosed. In the method, a semi-solid state metal-based material is provided. The semi-solid state metal-based material is stirred and nano-sized reinforcements are added into the semi-solid state metal-based material to obtain a semi-solid state mixture. The semi-solid state mixture is heated to a temperature above a liquidus temperature of the metal-based material, to achieve a liquid-metal-nano-sized reinforcement mixture. The liquid-metal-nano-sized reinforcement mixture is ultrasonically processed at a temperature above the liquidus temperature by conducting ultrasonic vibrations to the liquid-metal-nano-sized reinforcement mixture along different directions at the same time.
An elbow prosthesis can include a capitellar implant that has an articulating head and a stem. The articulating head can have a first substantially hemispherical portion and a second portion that collectively extend between lateral and medial sides of the articulating head and are separated by a plane. The first and second portions can generally extend between the lateral and medial sides. The second portion can generally have an attachment lobe that extends on the lateral side and that defines a passage therethrough. The passage can extend at least partially on the second portion.
Implantable assemblies/devices and methods are provided for manipulating energy transferred by members defining an articulating anatomical joint, wherein the members collectively define a path of motion. Assemblies/devices are provided with a first component configured to be attached to a first anatomical member of the anatomical joint, a second component configured to be attached to a second anatomical member of the anatomical joint; and a tension member joining the first and second components. The tension member is placed under tension to absorb energy transferred by the anatomical members when the first component is attached to the first anatomical member and the second component is attached to the second anatomical member and a distance between locations of attachment of the first and second components becomes smaller then an implant-defined distance between the locations.
An implant for therapeutically separating bones of a joint has two endplates each having an opening through the endplate, and at least one ramped surface on a side opposite a bone engaging side. A frame is slideably connected to the endplates to enable the endplates to move relative to each other at an angle with respect to the longitudinal axis of the implant, in sliding connection with the frame. An actuator screw is rotatably connected to the frame. A carriage forms an open area aligned with the openings in the endplates. The openings in the endplates pass through the carriage to form an unimpeded passage from bone to bone of the joint. The carriage has ramps which mate with the ramped surfaces of the endplates, wherein when the carriage is moved by rotation of the actuator screw, the endplates move closer or farther apart.
A bone infusion apparatus for interbody grafts includes a container; a retainer, the retainer including a recess for receiving therein bone graft material; and a lid including a plunger assembly. A method of preparing bone including cadaver bone for use in cervical fusion includes: placing cadaver bone combined with bone collected from a patient into a recess of the retainer; placing the retainer in the container; filling the container with a liquid; attaching a lid the container; depressing a plunger of the lid such that a press head advances toward the retainer causing a dynamic pressure to act on the cadaver bone combined with the bone collected from the patient; suctioning the liquid from the container; removing the combined bone from the retainer; and placing the combined bone removed from the container into a vertebral interspace of the patient.
The present invention generally relates to a method of using a matrix as a barrier for unwanted cell attachment and bone formation in unwanted areas of the human body during implant procedures. More specifically, a growth-inhibiting matrix may be used to prevent migration of osteo-inductive agents or bone tissue from an intervertebral disc space through the outer bands of annulus fibrosis that abuts the spinal tissue, canal, and other surrounding areas.
This equipment includes at least one U-shaped clip (1) whose lateral branches (10) have sections and widths such that they may be inserted in the vertebral bodies (100) of two vertebrae by impaction on the intermediate branch (11) of the clip (1), so as to rest along the cortical bones of the vertebral bodies, and whose intermediate branch (11) is deformable in such a way as to allow a reduction of the distance between the lateral branches (10); the intermediate branch, before implantation, has a length such that one of the lateral branches (10) may be positioned slightly above the cortical bone forming the plate of the subjacent vertebra while the other lateral branch (10) may be positioned slightly below the cortical bone forming the plate of the subjacent vertebra, and has, after deformation, a length such that the two lateral branches (10) may be brought closer to each other.
In accordance with certain embodiments of the present disclosure, a process of forming a prosthetic device is provided. The process includes forming a dispersion of polymeric nanofibers, a fiberizing polymer, and a solvent, the dispersion having a viscosity of at least about 50,000 cPs. A tubular frame is positioned over a tubular polymeric structure. Nanofibers from the dispersion are electrospun onto the tubular frame to form a prosthetic device. The prosthetic device is heated.
Dynamic colorectal PDT methods, devices and photosensitizer compositions to treat abnormal cell growth in anal tissue such as perianal and intra-anal intraepithelial neoplasia grade III are presented. Dynamic colorectal PDT method comprises the steps of administering topically, intravenously or orally a photosensitizer composition; irradiating; monitoring treatment parameters before, during and/or after irradiation. Photosensitizer composition comprises Temoporfin and excipients/carriers, appropriate for the application method. An applicator is provided for colorectal PDT treatments enhancing irradiation delivery and monitoring treatment parameters. Preferably, applicator is made of a material, used to monitor the fluence rate simultaneously while doing optical spectroscopy. Measurement probe devices are provided for monitoring PDT treatment parameters in-vivo. A device for colorectal PDT treatment is also provided, comprising laser radiation source operating at about 400 and 800 nm; excitation laser radiation source operating at about 650 nm for fluorescence measurements; multichannel dosimetry device; long pass filter; waveguides and measurement probes.
A spinal fixation titanium alloy rod fixes a plurality of spinal-fixing screws embedded and fixed in vertebrae of a human body. The rod is cylindrically shaped, has a sufficient length for coupling with the spinal-fixing screws, and has a diameter adjusted to 4 to 7 mm. In the titanium alloy constituting the rod, Nb content is 25 to 35 percent by weight, Ta content is such that the Nb content +0.8×Ta content ranges from 36 to 45 percent by weight, Zr content is 3 to 6 percent by weight, and the remainder is Ti and unavoidable impurities, excluding vanadium. The titanium alloy is manufactured by swaging processing at a cross-sectional reduction rate of at least 90%, and aging the swaged titanium alloy by heating at a temperature of 600 to 800K, preferably 700 to 800K, for 43.2 ks to 604.8 ks.
A forceps includes an end effector assembly having first and second jaw members. Each of the jaw members includes a proximal flange extending therefrom. Each of the proximal flanges defines a bifurcated configuration having first and second spaced-apart flange components. The first flange component of the first jaw member is configured to pivotably engage the second flange component of the second jaw member via a first protrusion-aperture coupling. The first flange component of the second jaw member is configured to pivotably engage the second flange component of the first jaw member via a second protrusion-aperture coupling different from the first protrusion-aperture coupling. One or both of the jaw members is pivotable relative to the other about the first and second protrusion-aperture couplings between a spaced-apart position and an approximated position for grasping tissue therebetween.
A retrieval portion is attached to an implantable device to facilitate retrieval of the implantable device in the unlikely event of embolization. The retrieval portion may comprise one or more loops, or a plurality of extensions. Methods of retrieving an implantable device are disclosed. Various adapters are disclosed for use with a conventional snare for grasping an implantable device.
A vascular implant formed of a compressible foam material has a compressed configuration from which it is expansible into a configuration substantially conforming to the shape and size of a vascular site to be embolized. Preferably, the implant is formed of a hydrophilic, macroporous foam material, having an initial configuration of a scaled-down model of the vascular site, from which it is compressible into the compressed configuration. The implant is made by scanning the vascular site to create a digitized scan data set; using the scan data set to create a three-dimensional digitized virtual model of the vascular site; using the virtual model to create a scaled-down physical mold of the vascular site; and using the mold to create a vascular implant in the form of a scaled-down model of the vascular site. To embolize a vascular site, the implant is compressed and passed through a microcatheter, the distal end of which has been passed into a vascular site. Upon entering the vascular site, the implant expands in situ substantially to fill the vascular site. A retention element is contained within the microcatheter and has a distal end detachably connected to the implant. A flexible, tubular deployment element is used to pass the implant and the retention element through the microcatheter, and then to separate the implant from the retention element when the implant has been passed out of the microcatheter and into the vascular site.
A system for closing an aperture in a biological tissue includes an implant deployment device having at least one frame arm. At least one clip is connected to the at least one frame arm and configured to releasably retain a surgical implant to the frame arm. A lock bar including at least one spring member is disposed on the at least one frame arm and is configured to bias the clips towards a closed position.
A threading device assembly for use in plastic surgery that includes a threading rod and a removable suture assembly secured to the threading rod. The threading rod includes an elongated tube with first and second opposite ends and a reduced diameter portion defined therein, and a translucent light guide extending through the elongated tube. The light guide allows light to be transmitted through the material comprising the light guide from one end of the tube to the other. The removable suture assembly includes a cuff positioned in and at least partially around the reduced diameter portion of the elongated tube, and a suture secured to the cuff.
The present invention relates to a method for determining the region of the body in which an anatomical part of the body is situated, said method including the following steps: anatomical point data is provided which includes information concerning a spatial pattern of positions of patient landmarks of a part of a patient's body which corresponds to the anatomical part of the body; landmark data is provided which includes information concerning a spatial pattern of positions of model landmarks of a model of the anatomical part of a patient's body; wherein, assuming that the patient landmarks represent the same landmarks as the model landmarks, the region of the body in which the part of the patient's body is situated is determined on the basis of the landmark data and the anatomical point data.
A tissue retrieval system can include a tissue retrieval bag with an elongate profile. The tissue retrieval bag can have a relatively large volume, but be rollable to a stowed configuration to fit in a relatively small diameter introducer. The tissue retrieval system can include one or more support arms coupled to the tissue retrieval bag, the support arms biased to position the tissue retrieval bag in an access position once deployed from the introducer. A tissue retrieval system can have a hybrid tissue retrieval bag including material properties that vary along the depth of the bag from an open end to a closed end. A tissue retrieval bag can be used in conjunction with an introducer, or as a stand alone tissue retrieval bag.
A surgical cutting guide is described which can guide a cutting implement to cut in a pair of planes at a defined relative orientation. The cutting guide comprises a first plate defining a first cutting plane, a second plate defining a second cutting plane at an angle to the first cutting plane; and a base member to which both the first plate and the second plate are attached. The first and second cutting planes intersect each other at a line of intersection and both the first plate and the second plate extend beyond the line of intersection.
An instrument for controlled delivery of a device to a target area near a defect of a bone is provided. The instrument comprises a guide frame having a plurality of device portals, each portal defining a trajectory. The guide frame further includes visual markers for aligning the guide frame to an anatomical landmark on the bone to be treated. The instrument also includes a holder for releasable attachment with the guide frame. Each device portal is configured to provide accurate and controlled delivery of the device to the target area. In one example, the markers are radiopaque, and are visualized through fluoroscopy. A method of using the instrument is also provided.
A treatment system includes a seal member, a maintaining member and a control section, and is configured to exert energy to a living tissue to treat the living tissue. The seal member is configured to join a sealed region which seals desirable regions of at least two living tissues when the energy is exerted to the sealed region. The maintaining member is configured to maintain the living tissues in the vicinity of the sealed region being brought into contact with each other when the energy is exerted to the living tissues. The control section is configured to offset energy output timings of the seal member and the maintaining member.
A laparoscopic liver resection device is described. The device combines the Radiofrequency Ablation (RFA) technology with a cutting mechanism, a blood-flow sensor and a flexible actuation mechanism to simultaneously coagulate and cut the liver tissue and detect the presence of blood flow to confirm avascularity. The present invention eliminates the risk of excess bleeding due to cutting too deep and reduces recovery time and the time spent on re-coagulation of coagulated areas, thereby shortening duration of surgery. Also embodiments prevent excess ablation by stopping ablation activity on the target tissue as soon as insufficient or no blood flow in the target tissue is detected. Thus a closed loop control for a bloodless tissue/organ division method is provided.
Embodiments of the disclosure include devices and systems for using an end effector. In an embodiment, a medical device may include an articulation section. The articulation section may be operatively associated with an elongate articulation member configured to move the articulation section, wherein the articulation section can be configured to receive part of a conductive member. The medical device may also include an end effector. The end effector may include an electrode and a non-conductive section encasing a junction between the electrode and the conductive member, wherein the non-conductive section can be moveably coupled to the articulation section and can be fixedly coupled to the elongate articulation member.
According to some embodiments, a method of treating a subject having diabetes or symptoms associated with diabetes is provided. The method includes delivering a neuromodulation catheter within a vessel (e.g., hepatic artery) having surrounding nerves that innervate the liver (e.g., sympathetic nerves of the hepatic plexus). The method may also include modulating (e.g., disrupting, ablating, stimulating) the nerves by mechanical compression, energy delivery, or fluid delivery.
A skin graft applicator with a handle member and a roller member is described for use in applying a skin graft to a patient. The skin graft applicator has a manipulator pad for positioning the skin graft, and a roller member for forcing air and fluid from underneath the skin graft ensuring the proper bond between graft and tissue.
A device for the treatment of pneumothorax especially in neonates, which facilitates the simple one-hand introduction of a catheter-sheathed stylet through the chest wall and which contains a one-way valve outside the chest for the stat evacuation of the intrathoracic air or fluid. The device is capable of secure fixation to the chest wall until deemed no longer needed at which point it is quickly removable. The thoracic cavity is entered by a stylet which is surrounded by a catheter, the catheter lumen continuous with that of a lumenized dome which communicates with at least one upper port and one-way valving. One port is configured to allow Luer-Lok suction in the event of pleural effusion or hemothorax.
A catheter for insertion into a vascular system of a patient and for directing fluid flow includes a catheter body having a longitudinal axis and longitudinally spaced proximal and distal catheter ends with an intermediate catheter portion defined therebetween. An intermediate catheter outlet in the catheter body is located in the intermediate catheter portion and is spaced longitudinally from the proximal and distal catheter ends. A first lumen is defined within the catheter body and has longitudinally spaced proximal and distal first lumen ends with a reversing bend located therebetween, the first lumen providing fluid communication between the proximal catheter end and the intermediate catheter outlet. The reversing bend is located longitudinally between the intermediate catheter outlet and the distal catheter end. The reversing bend directs fluid flow to turn approximately 180° as the fluid flows through the first lumen. A method of using the catheter is also described.
A device for delivering fluid to a user includes a housing, a drive motor assembly in the housing, a force sensor, and an electronics module. The drive motor assembly regulates delivery of fluid by actuating a piston of a fluid reservoir, and the force sensor generates output levels in response to force imparted thereto during, for example, fluid delivery operations. The electronics module processes the output levels of the force sensor to assess the operating health of the force sensor, to check for occlusions in the fluid delivery path, and to monitor the seating status of the fluid reservoir.
Absorbent articles having a liquid permeable topsheet, a liquid impermeable backsheet, and an absorbent core disposed between said topsheet and said backsheet are disclosed. The absorbent articles include a thermoplastic elastomer joined to or disposed in a stretch zone on at least one component or region of the absorbent article to impart an elastic resistance that provides sizing or shaping capabilities to the article. The absorbent article can be in the form of diapers, pull-on diapers, training pants, sanitary napkins, wipes, bibs, incontinence briefs or inserts.
The present invention provide with a diaper sheath comprising: an inner and outer panel, each of said inner and outer panels having front and back portion connected by an intermediate portion, said front portion of the inner panel having an opening; and a front flap attached to said front portion of said inner panel, and said opening is covered by said front flap. The diaper of the present invention is much easier and convenient to adjust the insert from the opening at the front portion. With the flap at the front portion, parents can choose to use a biodegradable pad to insert in the flap and lay on the top of the inner panel.
Absorbent articles such as disposable diapers and disposable pant like garments are disclosed. In particular, absorbent articles such as disposable diapers and pants having an improved barrier cuff structure for improved fit are described. The placement of a barrier cuff structure having a tackdown point near the waistband of the article tends to “pull down” the waistband and may cause sagging. Intermediate tackdown bonds are disclosed to achieve the containment benefits of a barrier cuff structure without sacrificing fit characteristics of the article. The intermediate tackdown may be intermediate one or both of the longitudinal ends of the barrier cuff strip and the lateral side edges of the strip. Additionally, the relationship of forces, angles, and design characteristics of aspects of the articles and sagging are disclosed.
An eye treatment system for performing an ocular surgical procedure contains an eye treatment probe or handpiece, a treatment console, an eye treatment cassette, and a pump formed by the engagement of the treatment cassette with the treatment console. The handpiece is configured to provide at least irrigation fluid to, and aspiration of fluid from, a subject eye. The treatment console comprises a controller configured to control the eye treatment probe. The eye treatment cassette engages the treatment console to couple the eye treatment probe with the treatment console. The pump comprises a pump head having a plurality of projections disposed to rotate about an axis, a ramp disposed near the rotating projections, and a resilient channel configured to transfer fluid when engaged by the ramp and the plurality of projections. The ramp is configured to reduce pressure fluctuations with the eye during a surgical procedure and comprises and entrance portion, a central portion, and an exit portion. The entrance portion has an arcuate extent over which the projections close the channel as the head rotates. The central portion has an arcuate extent over which the channel is sealed by the projections as the head rotates. The exit portion has an arcuate extent over which the projections open the channel as the head rotates. The ramp is configured such that the arcuate extent of the entrance portion is unequal to the arcuate extent of the exit portion.
A flow control device includes a connector defining a first receiving formation for receiving a first conduit, a second receiving formation for receiving a second conduit and a cross member separating the first receiving formation and the second receiving formation. An orifice plate is received in the cross member to control flow of fluid, in use, through the conduits received in the first and the second receiving formations of the connector, the orifice plate defining at least one substantially frustoconical orifice.
A medicament delivery device has a housing and a sleeve; a shield within and protruding from the housing; a container having a delivery member, a chamber containing a medicament, and a piston; a drive mechanism having a spring and a plunger rod in contact with the piston; and a container holder having a first locking device releasably connected to a corresponding locking device on the sleeve for holding the holder in an initial state against the drive mechanism and a second locking device surrounded by the sleeve and releasably connected to a corresponding locking device on the plunger rod for protecting the piston from force from the drive mechanism until the holder has moved a certain predetermined distance. The shield releases the first locking device when the shield is pressed against a medicament delivery site, whereby the drive mechanism forces the holder the certain predetermined distance.
Ports for accessing a vessels within a patient include passageways that can guide needles or other access devices directly into the vessels. The ports can be implanted subcutaneously within a patient. Some ports may be used in the creation and use of vascular access buttonholes.
An enteral feeding device having an improved base adapted to be deployed outside the human body and a tube which is adapted to be deployed within a lumen or cavity of the body by insertion through a stoma from outside the body is disclosed. The base of the device has a recess directly surrounding at least a portion of the proximal end of the tube to permit increase air flow and minimize contact with the tissue immediately surrounding the stoma to facilitate tissue wellness and reduce patient side effects due to moisture build-up, skin irritation and granulation of the stoma tissue.
Air-in-line sensor systems and methods of using same are provided. In a general embodiment, the present disclosure provides an adapter including first and second cylindrical portions defining a fluid flow channel, the first cylindrical portion comprising two adjacent wedge-shaped protrusions. Each wedge-shaped protrusion is infrared transmittive and defines an outer surface and an inner surface. In another embodiment, an air-in-line sensor device includes a tube and an infrared reflective sensor having an infrared light emitter and an infrared light detector. The infrared light emitter and the infrared light detector are positioned at or near an adapter so that an infrared light can be transmitted to the adapter and at least a portion of the infrared light reflected off the adapter can be detected by the infrared light detector.
An access port assembly having an attachable catheter allows for inserting a guidewire into the catheter to aid in the placement of the integral catheter while still attached to the access port assembly. A method is described for placing an access port fixedly attached to a catheter into a patient using a guidewire inserted into the catheter.
[Problem]Disclosed is a shunt valve for treatment of hydrocephalus such that the flow rate of cerebrospinal fluid drained from the brain ventricles can be freely regulated without drastically changing the intraventricular pressure when the pressure thereof becomes abnormal after a transplant.[Means to Solve the Problem]A shunt valve for treatment of hydrocephalus which regulates the drainage amount of cerebrospinal fluid from the ventricles, and comprises a cured plastic substrate for stabilizing in a prescribed position, an inflow connector formed in a cylindrical shape to which a rear end of a ventricular catheter is connected, a first valve pressure variable device which regulates an increase and decrease in the flow rate of the cerebrospinal fluid with a first on-off valve according to changes in the intraventricular pressure and is capable of changing the opening and closing pressure into a plurality of levels, a second valve pressure variable device which regulates the increase and decrease of the flow rate of the cerebrospinal fluid with a second on-off valve according to changes in the fluid pressure of the cerebrospinal fluid drained from an outflow channel of the first valve pressure variable device and is capable of changing the opening and closing pressure into a plurality of levels, and an outflow connector formed in a cylindrical shape to which a rear end of a peritoneal catheter is connected.
A pneumatic compression garment includes a flexible member for placement on a limb of a human body. A bladder in the flexible member defines an inflatable chamber. The bladder has an opening through which the inflatable chamber is inflated. A port mounted on the bladder has an air inlet adapted for communication with a source of pressurized air and an air outlet in communication with the inflatable chamber via the opening in the bladder. Pressurized air is delivered from into the inflatable chamber for inflating the inflatable chamber and thereby applying a compression force to the limb when the flexible member is in place on the limb. An air diverter affixed to an inside surface of a first sheet of the bladder and configured to divert air entering the inflatable chamber from directly impinging against an inside surface of a second sheet of the bladder.
A goniometer has three potentiometers with axes of rotation that intersect at a point for measuring angular range of motion of an anatomy, such as of the spine or jointed appendages. The intersecting axes facilitate calculation of angle based on potentiometer output and allow the rotations on each of the three axes to be measured independently and simultaneously without mechanical or electrical cross talk. The angular measurements may be recorded on a computer for analysis and playback and may be continuously captured over a range of motion. The captured data may be compared to samples from the same person or others to aid in assessment of function.
Systems and methods for delivering and/or receiving a substance or substances, such as blood, from subjects. In one embodiment, devices and methods for receiving blood from a subject employ devices including a substance transfer component (such as one or more microneedles), and a storage chamber having an internal pressure less than atmospheric pressure prior to receiving blood. In certain embodiments, substances may be received from and/or delivered to the subject with relatively little pain. The pain may be assessed, for example, using pain scales such as the WONG BAKER FACES Pain Scale. The device may be self-contained, applied to the skin, and activated to receive blood from the subject. The device, or a portion thereof, may be processed to determine the blood and/or an analyte within the blood using sensors or agents in the device or an external apparatus. Other aspects of the present invention are directed at other devices for receiving bodily fluids kits involving such devices, methods of making such devices, methods of using such devices, and the like.
The present invention relates to a sampling instrument adapted for taking a sample in situ and in vivo or taking a sample ex vivo of a target tissue or body structure, in a maximum quantity of less than 10−6 g, the instrument comprising an elongated active member (10) with a distal operative end (11) having at least one retaining surface (12) arranged for contacting directly the target tissue or body structure, capturing and retaining molecules of the target tissue or body structure thereto.
An optical coherent tomographic image forming apparatus includes: a first switch for instructing rotation of the optical deflection unit at a first speed; a second switch for instructing rotation of the optical deflection unit at a second speed which is higher than the first speed; and a driving controller which drives the optical deflection unit rotationally at the first speed in case of detecting instruction operation of the first switch and which changes the rotation speed of the optical deflection unit to the second speed, in case of detecting instruction operation of the second switch, under the condition that the optical deflection unit rotates at the first speed when the second switch is instructionally operated.
High-frequency ultrasound imaging can be performed with greater quality and suppressed grating lobes by using methods and systems for effectively reducing the temporal length of transmit grating lobe signals in received ultrasound echoes. Systems and methods are provided for improved high-frequency ultrasound imaging. In various aspects, the method of shortening the time domain of grating lobe signals comprises splitting an array of N transmit elements into K sub-apertures. In further aspects, the grating lobes are suppressed by performing signal processing of the shortened grating lobe signals. In certain aspects, the signal processing method comprises weighting the samples by a calculated phase coherence factor.
A mitral valve is detected in transthoracic echocardiography. The ultrasound transducer is positioned against the chest of the patient rather than being inserted within the patient. While data acquired from such scanning may be noisier or have less resolution, the mitral valve may still be automatically detected. Using both B-mode data representing tissue as well as flow data representing the regurgitant jet, the mitral valve may be detected automatically with a machine-learnt classifier. A series of classifiers may be used, such as determining a position and orientation of a valve region with one classifier, determining a regurgitant orifice with another classifier, and locating mitral valve anatomy with a third classifier. One or more features for some of the classifiers may be calculated based on the orientation of the valve region.
The invention concerns a device for treatment of an organ or tissue of a living being. The device comprises at least one treatment transducer for emission of ultrasound waves, preferably high intensity focused ultrasound (HIFU) waves, focusable on a focal point within or on the surface of said organ or tissue, as well as means for rotating said treatment transducer around an axis which intersects said focal point. The device further comprises synchronization means for synchronizing the rotation of the treatment transducer with at least the emission of ultrasound waves from said treatment transducer and/or an additional imaging transducer.
An apparatus for accessing the lumen of a vessel includes a handle providing a controller for operating the apparatus, an image capturing instrument secured to the handle, a display secured to the handle, wherein images captured by the image capturing instrument are displayed on the display, and a robotic platform coupled to the handle. The robotic platform includes a body, a first motor coupled to the body, wherein the first motor adjust the robotic platform to achieve a target insertion depth, and a cartridge carrier pivotally coupled to the body, wherein the robotic platform is adjustable to achieve the target insertion depth. The apparatus also includes a disposable cartridge attached to the cartridge carrier. The disposable cartridge includes a needle slideably coupled to the disposable cartridge, wherein the needle slides to extend to the target insertion depth, and a sheath slideably coupled to the disposable cartridge, wherein the sheath slides to extend to the target insertion depth.
A portable ultrasound imaging system is provided. The system includes a probe for acquiring ultrasound image data. A memory stores the acquired ultrasound image data. A processor generates an image based on the stored ultrasound image data. A presentation layer is provided for remotely accessing the generated image to display the generated image at a remote location.
A surgical access port is provided for insertion through an incision formed in a body wall of a patient. The surgical access port generally includes a sleeve assembly having a folding assembly provided at a proximal end of the sleeve assembly. The sleeve assembly includes a flexible sleeve and a flexible distal ring provided at a distal end of the flexible sleeve. A proximal end of the sleeve assembly includes a pocket formed in the sleeve material. The folding assembly is located in the pocket and generally includes a proximal ring and one or more ring knobs rotatably mounted on the proximal ring. Locking structure, in the form of a ratchet and pawl mechanism, may be provided to secure the ring knobs in position relative to the proximal ring.
A system for treating neurological conditions by low-frequency time varying electrical stimulation includes an electrical device for applying such low-frequency energy, in a range below approximately 10 Hz, to the patient's brain tissue. An implantable embodiment applies direct electrical stimulation to electrodes implanted in or on the patient's brain, while a non-invasive embodiment causes a magnetic field to induce electrical currents in the patient's brain.
A combined magnetic and irradiating device for therapeutic purposes applies infrared rays and magnetic force. The device includes a shell designed to be gripped by a user, including an outer surface shaped by at least three flat areas, and an inner bore-hole formed inside the shell for receiving first and second magnets in close connection with each other. Both magnets have north and south pole surfaces and an axis, respectively, aligned with each other, and said north pole surface of the first magnet is exposed on a surface of the shell. Windows having an inner rim are arranged on each flat area of the shell. Said close connection is established between the south pole surface of the first magnet and north pole surface of the second magnet. At least one infrared radiating tablet is fixed in said window and abutted against said rim by a clamp placed inside said bore-hole.
A radiotherapy treatment plan for irradiation of an object to be irradiated is determined. The object to be irradiated includes a number of irradiation areas and the object to be irradiated is irradiated with a number of beams from different directions. The method includes determining a number of total dose conditions. One of the number of total dose conditions is assigned to a respective one of the number of irradiation areas. The method further includes determining a number of single beam dose conditions. One of the single dose conditions is assigned to a respective one of the number of beams and a respective one of the number of irradiation areas. The method also includes determining irradiation parameters for the number of beams as a function of the number of total dose conditions and the number of single beam dose conditions.
Folding mandrel, device and method for manufacturing glued sleeves. The invention relates to a folding mandrel for a device for manufacturing glued sleeves, in particular paper sleeves for the manufacture of paper cups, where the folding mandrel is provided for winding of a plane segment and is so dimensioned that in the wound-on state of the segment an overlap containing adhesive is obtained. In accordance with the invention, the folding mandrel is provided with at least one recess for receiving any adhesive escaping from the overlap.
A torque transmission arrangement for a motor vehicle has a drive element (4) and at least one output element connected to one another via a transmission (6) and a shift clutch arrangement (8). The shift clutch arrangement (8) has an actuator (40) that moves a first clutch element (32) axially in the direction of a second clutch element (34) via a displacement element (42, 44) in such a way that a positive connection can be produced between the drive element (4) and the output element. The first clutch element (32) bears via an axial bearing arrangement (50) against the displacement element (42, 44) as seen in the axial direction. The axial bearing arrangement (50) has a rolling bearing (58) and a bearing disk element (62) directed toward the first clutch element (32).
An electric drive module for use in electric vehicles includes an electric traction motor, a geared reduction unit driven by the electric motor, a differential unit interconnecting a pair of axleshafts to a pair of wheels, and a disconnect mechanism for selectively coupling and uncoupling the geared reduction unit and the differential unit. The disconnect mechanism is configured to normally couple the geared reduction unit to the differential unit. The disconnect mechanism uncouples the geared reduction unit from the differential unit to prevent peak torque transients and torque reversals between the electric motor and the wheels.
A secondary assembly drive of an internal combustion engine and a method for operating same are provided. The secondary assembly drive includes: a first drive wheel (1) which can be rotatably connected to a crank shaft (CR) of the internal combustion engine, an electric machine which can be operated either as a generator (AL) of as a motor (M) and a second drive wheel (2) which can be rotatably connected to the electric machine (AL, M), an air-conditioning compressor (A/C) and a third drive wheel (3) which can be rotatably connected to the air-conditioning compressor, a traction element (4) which rotates infinitely and which wraps around the drive wheels, and an actuable clutch (7) for disconnecting the drive of the electric machine and of the air-conditioning compressor from the crankshaft when necessary. In addition, the air-conditioning compressor is designed for operation in both rotational directions, and a reversal of the rotational direction between the generator operating mode and the motor operating mode of the electric machine is provided.
An isolating decoupler comprising a shaft, a pulley journalled to the shaft, a torsion spring engaged with the pulley, a wrap spring frictionally engageable with the shaft, the torsion spring and wrap spring connected in series such that each is torsionally loaded in a winding direction, the wrap spring comprising a variable cross-section having a first cross sectional dimension and a second cross sectional dimension, and the wrap spring temporarily releasable from the shaft in an overtorque condition by contact with the pulley urging the wrap spring in an unwinding direction.
An exemplary golf club head can comprise a body comprising a hosel bore defining a hosel bore axis and an adjustable sleeve comprising a plurality of longitudinal splines that engage with the body within the hosel bore such that the sleeve is configured to be secured within the hosel bore in a plurality of discrete rotational positions relative to the hosel bore axis. The sleeve can further comprise a shaft bore defining a shaft bore axis that forms a sleeve angle with the hosel bore axis when the sleeve is secured within the hosel bore. The square loft angle of the golf club head can be adjusted by changing the rotational position of the sleeve within the hosel bore. The club head can further comprise an adjustable sole piece that can be locked on the sole at a plurality of discrete positions to adjust face angle.
A gaming system is disclosed having a gaming terminal including at least one input device and at least one display device and a network coupled to the gaming terminal. At least one memory device stores assets of a wagering game. The assets include a first asset and a second asset. The second asset is capable of replacing the first asset. The memory device stores a rule set ranking a level of importance of the assets. Instructions are stored that, when executed by the at least one processor, cause the gaming system to negotiate between the gaming terminal and the network to select either the first asset or the second asset. The selection is made according to the level of importance of the first and second assets in the stored rule set. The wagering game with the selected asset is then displayed.
A gaming machine with more gaming excitement is provided. The gaming machine includes a cabinet; a lamp body provided on a front surface of the cabinet; a sensor configured to detect a player's gesture with respect to the lamp body; an image display panel configured to execute an effect in sync with the gesture; and a controller used to start a game, the controller starting the detection of the player's gesture by the sensor at a timing corresponding to the state of the game, and while the player's gesture is being detected, executing the effect by the upper image display panel in sync with the detected player's gesture.
A method, apparatus, article of manufacture, and a memory structure for providing a payout to a player is disclosed. An ATM or ATM-like device is used to cash out of and cash into gaming devices with the player's fingerprint used to securely transfer the cash-in or cash-out data between the gaming device and the ATM. An embodiment is disclosed in which the information is passed between the ATM and the gaming device via a token.
A gaming system, gaming device, and gaming method including a symbol generator, where a number of awards available to the player in a single activation of the symbol generator and/or which awards are available to a player in a single activation of the symbol generator are based on an occurrence of one or more triggering events.
A system and method manages an electronic gaming environment. The gaming environment includes at least one gaming device. The system includes a database and a computer coupled to the database. The database stores system and user account data for at least one user and establishes a default language for the system. The computer is networked to the device. A user interface, associated with either the computer or the gaming device identifies a user, interacts with the user, and provides access to the system as a function of the identity of the user. The user interface is displayed in (a) in a preferred language of the identified user or (b) in the default language of the system if no preferred language is specified.
A method and gaming machine for playing a game with area and numerical winning thresholds. The method and machine present a plurality of distinct elements which are grouped into a plurality of subsets whereby a player can select both a sub-plurality of elements and at least one subset. A set of random elements is selected from the set of elements which also determines at least one random subset. The set of random elements is compared to the sub-plurality of player selected elements and the player selected subset to the random subset. A player is rewarded if the set of random elements and the set of player selected elements have a pre-determined minimum number of common elements and/or if the plurality of player selected subsets and the plurality of random subsets have a second, pre-determined minimum number of common subsets.
An embodiment includes a first space, a second space, a first damper, a second damper, and a third damper. The first space is connected to a cold space, having cold air reside therein to send to the cold space. The second space has return air reside therein, as it is discharged from a hot space. The first damper has an opening adjusted under control of a controller to take in outdoor air to the first space, and is operable to have an open state in an emergency with a server being supplied with power. The second damper has an opening adjusted under control of the controller to discharge return air in the second space, outside thereof, and is operable to have an open state in the emergency. The third damper has an opening adjusted under control of the controller to recirculate return air in the second space to the first space.
A deboning system for an arm part of bone-in meat includes: a clamp; at least one forearm-bone incision making device; an olecranon incision making device; and a forearm-bone separation device, wherein the at least one forearm-bone incision making device includes a robot arm and a forearm cutter attached to the robot arm, and the olecranon incision making device includes a pair of olecranon cutters.
A knife sharpener having an angled bolster for providing predetermined sharpening angles with respect to the sharpening surface is provided. The angled bolster of the knife sharpener preferably includes two different angled surfaces for establishing at least two different predetermined sharpening angles for a cutting implement to be sharpened. The angled bolster is configured to set up the knife sharpening angle at predetermined angles with respect to the sharpening surface.
A tool is disclosed for selective honing of the outer diameter of a cylinder using an abrasive belt in semi-circular contact upon the outer-diameter of a cylindrical work-piece to perform a similar function to honing the inner-diameter of a hollow cylinder. The belt is retained within the tool body by U-shaped restraint arms, and a slot in the tool body. A clamp block retains the ends of the belt which exit the slot. Springs on the arms, and contact of the block on the outside of the tool body, force the belt into a triangular shape inside the body. A cylindrical work-piece inserted within the triangular shaped belt causes the belt to deform into three semi-circular areas of contact between the belt and work-piece. When the work-piece is rotated, the belt abrades material from the work-piece.
Headgear that can be converted into another object, comprising a figurine provided with a hollow base which, in at least one configuration, defines an object including a volume for receiving an element. In a second configuration, the hollow base can be turned partially inside out to form a second object including another reception volume and, in a third configuration, the hollow base can be turned fully inside out to form a third object.
In a connector terminal connected to an electric wire in which a conductor is covered with an outer cover, the terminal includes a barrel portion that is exposed from the outer cover and is to be crimped to the conductor coated with a covering, and an electrical connection portion electrically connected to a mating terminal, wherein a trench or a projection that is provided along a direction perpendicular to an axis of the electric wire are formed in an inner surface of the barrel portion, and a depth of the trench or a projecting dimension of the projection is made smaller than a covering thickness of the covering.
Electrical terminals and methods of manufacturing the same are disclosed. An example terminal is disclosed that comprises a housing and a wire clamp positioned within the housing to secure a wire in electrical contact with a connector pin, the connector pin extending out a bottom surface of the housing to be electrically connected to a printed circuit board, the housing is to have one or more feet to separate the bottom surface of the housing from the printed circuit board.
A rail-based fastening structure for terminal blocks includes a fastening clip, a positioning rail and a bus body. The fastening clip has a base plate and two side plates each extending upward from the base plate and having an engaging hook. The positioning rail includes a bottom plate and two tracks extending upward and then outward from two opposite sides of the bottom plate, so that the bottom plate and the tracks define a valley. The bottom plate has an opening. The bus body deposited in the valley has a slot and two shoulder portions. The shoulder portions are positioned at two sides of the slot and extend toward the slot. The fastening clip is inserted into the opening through the slot so that the engaging hooks engage with the shoulder portions, respectively. Thereby, the rail-based fastening structure allows quick and convenient mounting/dismounting operation, low manufacturing costs and firm installation.
There is provided a connector capable of reliably preventing a short circuit without causing increase in cost. The connector includes a terminal which is joined to an electric wire, a housing which accommodates a terminal joint part which is a joint portion of the electric wire and the terminal, a sealing member which is made of a resilient material having waterproof and insulation properties to seal between the housing and the terminal joint part, and a shield member which covers the housing and the electric wire near the terminal joint part, wherein the sealing member is formed integrally with an electric wire protecting part which extends along the electric wire to cover the electric wire, and the electric wire protecting part is interposed between the electric wire and the shield member.
A pressing terminal includes an outer conductive member having a shield outer tube; an inner conductive member; and a dielectric member. The dielectric member includes a protruding portion fitted into the shield outer tube so that a signal line pressing portion of the inner conductive member is situated at a pressing tool insertion opening portion. The dielectric member is inserted into a shield outer tube with the protruding portion thereof sliding against the shield outer tube. A terminal pressing device includes an anvil unit and a crimper unit. Upon attaching the signal wire, a claw portion of a signal line crimper of the crimper unit is inserted into a claw insertion groove portion of a signal line anvil of the anvil unit. A terminal pressing anvil portion of the signal line anvil is ushered to a terminal pressing anvil insertion portion of the signal line crimper.
A clamping apparatus includes a base, a vertical support member coupled to the base, and a head member coupled to the vertical support member. The head member is configured to receive and engage a portion of a coaxial cable. Additionally, the base is configured to engage through a through hole or slot arranged through a substrate and provide electrical communication between a portion of the coaxial cable and the substrate.
A coaxial cable connector is provided, the connector includes: a connector body, a coupling member, a post having an post collar having a forward facing surface, a conductive grounding member operationally positioned axially forward of said forward facing surface of said post collar; whereby the coupling member, grounding member and post provide at least one grounding pathway.
Contact pads on structures such as printed circuits may be coupled to each other using printed circuit connectors such as board-to-board connectors. A printed circuit connector may have interlocking metal frame structures. The metal frame structures may be soldered to traces on the printed circuits. Rectangular openings in the metal frame structures may receive a rectangular contact array structure that is separate from the metal frame structures. The contact array structure may include a dielectric carrier structure and an array of conductive contacts. The dielectric carrier structure may align the contacts with respect to pads on the printed circuits to which the metal frame structures are soldered. The contacts may be formed from metal spring structures or conductive elastomeric structures that are compressed between respective printed circuit contact pads when the metal frame structures of a printed circuit connector are attached to each other.