Invention Grant
- Patent Title: Dihydroethidine analogues and uses thereof
- Patent Title (中): 二氢乙啶类似物及其用途
-
Application No.: US13516783Application Date: 2010-12-16
-
Publication No.: US09035057B2Publication Date: 2015-05-19
- Inventor: Robert H. Mach , Mark Mintun , Wenhua Chu , Laura Dugan
- Applicant: Robert H. Mach , Mark Mintun , Wenhua Chu , Laura Dugan
- Applicant Address: US MO Saint Louis
- Assignee: Washington University
- Current Assignee: Washington University
- Current Assignee Address: US MO Saint Louis
- Agency: Zackson Law LLC
- Agent Saul L. Zackson
- International Application: PCT/US2010/060735 WO 20101216
- International Announcement: WO2011/084585 WO 20110714
- Main IPC: C07D401/12
- IPC: C07D401/12 ; C07D221/12
Abstract:
Tracers for imaging distribution of reactive oxygen species (ROS) are disclosed. The tracers include radiolabeled dihydroethidine (DHE) analogues. Further disclosed are uses of the compounds, including methods of imaging tissue distribution of ROS in vivo by positron emission tomography (PET). Methods of synthesizing the compounds are also disclosed.
Public/Granted literature
- US20130079522A1 DIHYDROETHIDINE ANALOGUES AND USES THEREOF Public/Granted day:2013-03-28
Information query
