An image pickup apparatus capable of increasing the dynamic range and performing high-frame rate imaging. The image pickup apparatus includes a pixel section formed by arranging a plurality of pixels each including different types of pixels different in sensitivity to light, in a two-dimensional matrix form. Different types of ADCs perform analog-to-digital conversion of signals read out from the high-sensitivity pixels and low-sensitivity pixels in parallel and hold results in respective counter latch circuits. The pixel section has an interconnection layer including a plurality of interconnections for transferring the signals. One interconnection is used as a vertical read-out line for transferring signals from the low-sensitivity pixels, and another interconnection is used as a vertical read-out line for transferring signals from the high-sensitivity pixels.