Imaging systems and methods thereof

    公开(公告)号:US11185295B2

    公开(公告)日:2021-11-30

    申请号:US16845909

    申请日:2020-04-10

    Inventor: Tao Feng Hongdi Li

    Abstract: An imaging system includes a collimator assembly, a detector assembly and a control device. The collimator assembly is configured to collimate photons emitted from an imaged subject. The collimator assembly includes a plurality of slit-plates, each of the plurality slit-plates including one or more slits configured to collimate the photons in a first direction, and a plurality of slats parallel to a transverse plane of the imaging system. The detector assembly is configured to generate signals based on the collimated photons. The control device is configured to place the plurality of slit-plates in a plurality of locations to provide a plurality of fields of view of the imaging system.

    System and method for determining an activity map and an attenuation map

    公开(公告)号:US10438378B2

    公开(公告)日:2019-10-08

    申请号:US15686157

    申请日:2017-08-25

    Abstract: The present disclosure relates to systems and methods for determining a target activity map and a target attenuation map for producing a PET image. The systems may execute the methods to acquire, based on a PET system, a first dataset relating to coincidence events with TOF information, and a second dataset relating to single events. The systems may also execute the methods to determine a target activity map and a target attenuation map based on the first dataset and the second dataset through a plurality of iterations. The systems may further execute the methods to generate the PET image based on the target activity map and the target attenuation map.

    Devices, systems and methods for determining depth of interaction in positron emission tomography detectors

    公开(公告)号:US11409010B2

    公开(公告)日:2022-08-09

    申请号:US17181770

    申请日:2021-02-22

    Abstract: Methods and systems for detecting a three-dimensional position of a scintillation event converting a radiation into a light. For example, a system includes a crystal array including a plurality of crystal elements, a light sensor array including a plurality of light sensors, a first crystal pair of the plurality of crystal pairs corresponds to a first light sensor pair of the plurality of light sensor pairs; a second crystal pair of the plurality of crystal pairs corresponds to a second light sensor pair of the plurality of light sensor pairs; and a third crystal pair of the plurality of crystal pairs corresponds to the first light sensor pair and the second light sensor pair such that a scintillation event in the third crystal pair is detected by both the first light sensor pair and the second light sensor pair.

    System and method for detecting organ motion

    公开(公告)号:US10307116B2

    公开(公告)日:2019-06-04

    申请号:US15439898

    申请日:2017-02-22

    Abstract: A system and method of imaging a patient are provided. The system may include an acquisition configured to obtain a PET dataset relating to a target organ of a patient. The system may also include a processing module configured to determine a reference point of the target organ, divide the PET dataset into a plurality of data frames, and determine a motion signal of the target organ based on a plurality of first statistical parameters and a plurality of second statistical parameters. The processing module may further sort the PET dataset into a plurality of bins based on the motion signal.

    Methods and systems for emission computed tomography image reconstruction

    公开(公告)号:US10255694B2

    公开(公告)日:2019-04-09

    申请号:US15386048

    申请日:2016-12-21

    Abstract: The present disclosure relates to systems and methods for reconstructing an Emission Computed Tomography (ECT) image. The systems, having at least one machine each of which has at least one processor and storage, may perform the methods to obtain ECT projection data, the ECT projection data corresponding to a plurality of voxels; determine a plurality of gate numbers for the plurality of voxels, the plurality of gate numbers relating to motion information of the plurality of voxels; and reconstruct an ECT image based on the ECT projection data and the plurality of gate numbers.

    Systems and methods for determining kinetic parameters in dynamic positron emission tomography imaging

    公开(公告)号:US11172903B2

    公开(公告)日:2021-11-16

    申请号:US16052366

    申请日:2018-08-01

    Abstract: A method for imaging may include directing a PET scanner to perform scans of a subject injected with a tracer during a first time period. The method may also include generating PET images by reconstructing the PET data that are generated by the PET scanner based on the scans of the subject. The method may also include determining a first portion of a blood input function of the tracer in the subject based on the PET images. The method may also include determining an integral of a second portion of the blood input function based on a kinetic model, the PET data, and the first portion of the blood input function. The method may also include determining kinetic parameters of the kinetic model based on the PET data, the first portion of the blood input function, and the integral of the second portion of the blood input function.

    Systems and methods for determining plasma input function used in positron emission tomography imaging

    公开(公告)号:US11200669B2

    公开(公告)日:2021-12-14

    申请号:US16687845

    申请日:2019-11-19

    Inventor: Tao Feng Hongdi Li

    Abstract: The present disclosure provides a system and method for image generation. The method may include obtaining a first image acquired by an imaging device. The first image may include a representation of a blood vessel of a subject based on a tracer. The method may further include obtaining a blood vessel model configured to provide one or more constraints regarding one or more characteristics of the blood vessel. The method may further include generating a second image including a representation of the blood vessel based on the blood vessel model and the first image. An image resolution of the second image may be higher than an image resolution of the first image. The presentation of the blood vessel in the second image may satisfy at least one of the one or more constraints.

    Devices, systems and methods for determining depth of interaction in Positron Emission Tomography detectors

    公开(公告)号:US10962661B2

    公开(公告)日:2021-03-30

    申请号:US16528363

    申请日:2019-07-31

    Abstract: Methods and systems for detecting a three-dimensional position of a scintillation event converting a radiation into a light. For example, a system includes a crystal array including a plurality of crystal elements arranged at least along a first direction and a second direction, the plurality of crystal elements extending along a third direction between a first end and a second end, the plurality of crystal elements being configured to receive the radiation entered from the second end; wherein: the plurality of crystal elements is arranged into a plurality of crystal pairs; each of the plurality of crystal pairs optically coupled to one light bridge at the first end extending and bridging light along the first direction; each of the plurality of crystal pairs is optically coupled for the light in the second direction with at least a neighboring crystal pair only through two light tunnels.

    Systems and methods for positron emission tomography image reconstruction

    公开(公告)号:US10690782B2

    公开(公告)日:2020-06-23

    申请号:US15721783

    申请日:2017-09-30

    Abstract: The disclosure relates to PET imaging systems and methods. The systems may execute the methods to obtain an anatomical image of a subject acquired when the subject remains in a breath-hold status; obtain PET data of the subject, the PET data corresponding to a respiration signal with a plurality of respiratory phases of the subject, the respiratory phases including a first respiratory phase and a second respiratory phase; gate the PET data; reconstruct a plurality of gated PET images, the plurality of gated PET images including a first gated PET image corresponding to the first respiratory phase and a second gated PET image corresponding to the second respiratory phase; determine a first motion vector field between the first gated PET image and the second gated PET image; determine a second motion vector field between the anatomical image and the second gated PET image; and reconstruct an attenuation corrected PET image.

    Methods and systems for emission computed tomography image reconstruction

    公开(公告)号:US10360724B2

    公开(公告)日:2019-07-23

    申请号:US15618425

    申请日:2017-06-09

    Abstract: The present disclosure relates to a method and system for reconstructing an Emission Computed Tomography (ECT) image based on locally adaptive gating. ECT projection data relating to a subject may be obtained. The ECT projection data may correspond to a plurality of voxels in a reconstructed image domain. The ECT projection data may be divided into a plurality of frames. A plurality of intermediate images may be reconstructed according to the plurality of frames. A plurality of motion amplitudes of the plurality of voxels may be obtained based on the plurality of intermediate images. A plurality of gate numbers may be determined for the plurality of voxels based on the plurality of motion amplitudes of the plurality of voxels. A plurality of ECT images may be reconstructed based on the ECT projection data and the plurality of gate numbers.

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