Balloon catheter with flexible electrode assemblies
    1.
    发明授权
    Balloon catheter with flexible electrode assemblies 有权
    气球导管,带柔性电极组件

    公开(公告)号:US09060756B2

    公开(公告)日:2015-06-23

    申请号:US13413533

    申请日:2012-03-06

    Abstract: In some implementations, a method of ablating body tissue includes (a) locating an inflatable balloon portion of a cryotherapy balloon catheter at a treatment site internal to a patient's body, and inflating the inflatable balloon portion; (b) employing electrodes that are disposed on an expandable surface of the inflatable balloon portion to electrically characterize body tissue at the treatment site; (c) ablating the body tissue by supplying a cryotherapy agent to the inflatable balloon portion to cool the body tissue to a therapeutic temperature; (d) employing the electrodes to determine whether the ablating caused desired electrical changes in the body tissue; and (e) repeating (c) and (d) when it is determined that the ablating did not cause the desired electrical changes.

    Abstract translation: 在一些实施方案中,消融身体组织的方法包括(a)将冷冻治疗气囊导管的可充气球囊部分定位在患者身体内部的治疗部位处,并使可膨胀气囊部分膨胀; (b)使用设置在所述可膨胀气囊部分的可膨胀表面上的电极来电性地表征所述治疗部位的身体组织; (c)通过向所述可充气球囊部分供应冷冻治疗剂来将所述身体组织冷却至治疗温度来烧蚀所述身体组织; (d)使用电极来确定烧蚀是否引起人体组织中所需的电变化; 和(e)重复(c)和(d)当确定烧蚀不引起所需的电气变化时。

    Method for retrieving data stored in a database
    3.
    发明授权
    Method for retrieving data stored in a database 失效
    检索存储在数据库中的数据的方法

    公开(公告)号:US08588729B2

    公开(公告)日:2013-11-19

    申请号:US12493905

    申请日:2009-06-29

    Applicant: David Lawrence

    Inventor: David Lawrence

    CPC classification number: G06Q30/08 G06Q40/04

    Abstract: The invention provides a computer-implemented municipal bond trading system having a capability to conduct a private electronic auction of bid wanteds between a central brokers' broker and multiple prospective remote bidders and to maintain a reference database of accurate bond lot descriptions and identifications, notably, CUSIP (trademark) numbers.

    Abstract translation: 本发明提供了一种计算机实现的市政债券交易系统,其具有进行中央经纪人和多个潜在远程投标人之间出价投标的私人电子拍卖的能力,并保持准确的债券批次描述和标识的参考数据库, CUSIP(商标)号码。

    Automated account risk management
    4.
    发明授权
    Automated account risk management 有权
    自动账户风险管理

    公开(公告)号:US08527400B2

    公开(公告)日:2013-09-03

    申请号:US09812628

    申请日:2001-03-20

    Applicant: David Lawrence

    Inventor: David Lawrence

    CPC classification number: G06Q40/02 G06Q40/025 G06Q40/08

    Abstract: A computerized system and method for structuring risk management and assist a financial institution quantify financial, legal, regulatory and reputational risk associated with opening accounts related to management of financial assets and investments and facilitate analysis and quantification of risk. An automated account opening risk management system receives information quantifying factors relating to financial, legal, regulatory and/or reputational risk. The information is utilized to generate a risk quotient or other rating based upon a weighting algorithm applied to the criteria. The risk quotient is indicative of risk associated with an account. The quotient can be monitored on account opening, periodically or during a transaction. A log or other stored history can be created to help mitigate adverse effects relating to a problematic account by demonstrating to regulatory bodies, shareholders, news media and other interested parties that corporate governance is being addressed through tangible risk management processes.

    Abstract translation: 构建风险管理和协助金融机构的计算机化系统和方法,量化与开立与金融资产和投资管理有关的账户相关的财务,法律,监管和声誉风险,并促进风险分析和量化。 自动开户风险管理系统接收与金融,法律,监管和/或声誉风险相关的信息量化因素。 该信息用于基于应用于标准的加权算法来生成风险商或其他评级。 风险商指示与账户相关的风险。 可以在开户时定期或交易期间监测商。 可以创建日志或其他存储历史记录,以通过向监管机构,股东,新闻媒体和其他有关方面展示公司治理正在通过有形的风险管理流程来解决与有问题的帐户有关的不利影响。

    Providing cryotherapy with a balloon catheter having a non-uniform thermal profile
    5.
    发明授权
    Providing cryotherapy with a balloon catheter having a non-uniform thermal profile 有权
    用具有不均匀热分布的球囊导管进行冷冻治疗

    公开(公告)号:US08465481B2

    公开(公告)日:2013-06-18

    申请号:US12580572

    申请日:2009-10-16

    Abstract: A cryotherapy catheter can include an elongate member and an inflatable balloon portion at a distal end of the elongate member. The inflatable balloon portion can have an external surface and an interior chamber, and the external surface can include a cooling region and a thermally insulated region. The interior chamber can be configured to receive during a cryotherapy procedure a cryogenic agent for extracting heat from body tissue that is in contact with the cooling region. A thermal profiling component can be disposed in the interior chamber and configured to thermally insulate the thermally insulated region from the cryogenic agent to minimize heat extraction by the cryogenic agent from body tissue that is in contact with the thermally insulated region.

    Abstract translation: 冷冻治疗导管可以包括在细长构件的远端处的细长构件和可充气气囊部分。 可膨胀气囊部分可以具有外表面和内室,并且外表面可以包括冷却区域和绝热区域。 内部腔室可以被配置为在冷冻治疗过程期间接收用于从与冷却区域接触的身体组织提取热量的低温剂。 热成型部件可以设置在内部腔室中并且构造成使热绝缘区域与低温剂热绝缘,以最小化来自与绝热区域接触的身体组织的低温剂的热提取。

    Proprietary Risk Management Clearinghouse
    6.
    发明申请
    Proprietary Risk Management Clearinghouse 审中-公开
    专有风险管理信息交换机构

    公开(公告)号:US20120265675A1

    公开(公告)日:2012-10-18

    申请号:US13530681

    申请日:2012-06-22

    Applicant: David Lawrence

    Inventor: David Lawrence

    CPC classification number: G06Q40/08 G06Q20/10 G06Q40/12

    Abstract: A computerized risk management method and system for facilitating analysis and quantification of risk associated with a risk subject on a proprietary basis. A proprietary risk management system combines gathered information with information received from a source such as an automated risk management clearinghouse system and maintains a database to relate risk variables and calculate a measurement of risk. The measurement, which can be a risk quotient or other rating based upon a weighted algorithm applied to the risk variables, is indicative of risk associated with the risk subject. Actions commensurate with a risk quotient can be presented to a user to facilitate management of risk associated with a particular entity or transaction or other transaction. A stored history can be created to mitigate adverse effects relating to a problematic transaction.

    Abstract translation: 一种计算机化的风险管理方法和系统,用于便于在专有的基础上分析和量化与风险主体相关的风险。 专有的风险管理系统将收集的信息与来自诸如自动化风险管理交换所系统等来源的信息相结合,并维护一个数据库来关联风险变量并计算风险度量。 可以是基于应用于风险变量的加权算法的风险商或其他评级的测量值表示与风险对象相关的风险。 可以向用户呈现与风险商相称的操作,以便于管理与特定实体或交易或其他交易相关联的风险。 可以创建存储的历史记录,以减轻与有问题的交易相关的不利影响。

    Public offering risk management
    7.
    发明授权
    Public offering risk management 有权
    公开发行风险管理

    公开(公告)号:US08126800B2

    公开(公告)日:2012-02-28

    申请号:US10801238

    申请日:2004-03-15

    Applicant: David Lawrence

    Inventor: David Lawrence

    CPC classification number: G06Q40/04 G06Q40/00 G06Q40/06 G06Q40/08

    Abstract: The present invention provides an auction system that allows IPO sales to be offered in an open and transparent manner, wherein, a certain percentage (up to 100%) of shares in an IPO can be offered to qualified bidders at a “buy now” pre-auction price, set by an issuer and/or underwriter. Investors can be allowed to “bid some shares out of the auction process” and thus guarantee those investors' allocation while also allowing bidders to participate in an open auction for other shares. Shares of stock to be offered in an IPO can include a subset of pre-auction price shares and a subset of auction price shares. The pre-auction price shares are offered to pre-auction bidders at a pre-auction price, and auction shares are generally sold to the highest bidder. Pre-auction sales can serve as a catalyst for generating enthusiasm for an associated IPO auction.

    Abstract translation: 本发明提供一种拍卖系统,其允许以公开和透明的方式提供上市销售,其中,可以以“现在购买”预先向合格的投标者提供上市的一定百分比(高达100%)的股份 - 发行人和/或承销商设定的价格。 可以允许投资者“从拍卖过程中出价”,从而保证投资者的分配,同时允许投标人参与其他股票的公开竞价。 在IPO上提供股票的股票可以包括拍卖前价格份额的一部分和拍卖价格份额的一部分。 拍卖前拍卖价格以拍卖前拍卖价格提供给拍卖前投标人,拍卖股一般卖给最高出价者。 拍卖前的拍卖可以作为促成相关IPO拍卖的热情的催化剂。

    Ecology valve fuel return system operable in fluid isolation during gas turbine engine shut-down
    8.
    发明授权
    Ecology valve fuel return system operable in fluid isolation during gas turbine engine shut-down 有权
    在燃气涡轮发动机关闭期间可在液体隔离中操作的生态阀燃料返回系统

    公开(公告)号:US08122699B2

    公开(公告)日:2012-02-28

    申请号:US12327480

    申请日:2008-12-03

    CPC classification number: F02C7/232 F02C7/236 F02C9/26 F05D2220/50 F05D2260/85

    Abstract: An ecology valve (EV) fuel return system includes a housing assembly, an ecology valve, and a fuel routing assembly. The ecology valve includes an EV piston slidably disposed within the housing assembly for movement between a fuel storage position and a fuel return position, a fuel storage chamber defined by the EV piston and the housing assembly, and an EV control chamber defined by the EV piston and the housing assembly. The fuel routing assembly, which is fluidly coupled to the EV control chamber and to the fuel storage chamber, is configured to route fuel: (i) from the fuel storage chamber to a fuel supply system when a gas turbine engine (GTE) is in a start-up mode, and (ii) from the first fuel manifold and from the EV control chamber to the fuel storage chamber when the GTE is in a shut-down mode.

    Abstract translation: 生态阀(EV)燃料回收系统包括壳体组件,生态阀和燃料路线组件。 生态阀包括可滑动地设置在壳体组件内用于在燃料储存位置和燃料返回位置之间运动的EV活塞,由EV活塞和壳体组件限定的燃料储存室以及由EV活塞限定的EV控制室 和壳体组件。 流体耦合到EV控制室和燃料储存室的燃料路由组件被构造成在燃气涡轮发动机(GTE)处于燃料涡轮发动机(GTE)时将燃料(i)从燃料储存室路向燃料供应系统 启动模式,以及(ii)当GTE处于关闭模式时,从第一燃料歧管和从EV控制室到燃料存储室。

    BOND ISSUE RISK MANAGEMENT
    9.
    发明申请
    BOND ISSUE RISK MANAGEMENT 审中-公开
    债券发行风险管理

    公开(公告)号:US20110302075A1

    公开(公告)日:2011-12-08

    申请号:US13209632

    申请日:2011-08-15

    Applicant: David Lawrence

    Inventor: David Lawrence

    Abstract: The present invention provides an auction system that allows bond issue sales to be offered in an open and transparent manner, wherein, a certain percentage (up to 100%) of bonds in a bond issue can be offered to qualified bidders at a “buy now” pre-auction price, set by an issuer and/or lead manager. Investors can be allowed to “bid some bonds out of the auction process” and thus guarantee their allocation and also allow bidders to participate in an open auction for other bonds. Bonds to be offered in a bond issue can include a subset of pre-auction price bonds and a subset of auction price bonds. The pre-auction price bonds are offered to pre-auction bidders at a pre-auction price, and auction bonds are generally sold to the highest bidder. Pre-auction sales can serve as a catalyst for generating enthusiasm for an associated bond issue auction.

    Abstract translation: 本发明提供了一种允许以公开和透明的方式提供债券发行销售的拍卖系统,其中可以以“立即购买”的方式向合格的投标人提供债券发行中的一定百分比(高达100%)的债券 “拍卖前价格由发行人和/或主管经理设定。 投资者可以“投标拍卖过程中的一些债券”,从而保证其分配,并允许投标人参与其他债券的公开拍卖。 在债券发行中提供的债券可以包括拍卖前价格债券的一部分和拍卖价格债券的子集。 预拍卖价格债券以拍卖前价格提供给拍卖前投标人,拍卖债券通常以最高出价者出售。 拍卖前拍卖可以作为促成相关债券拍卖的热情的催化剂。

    Hedge fund risk management
    10.
    发明授权
    Hedge fund risk management 有权
    对冲基金风险管理

    公开(公告)号:US08069105B2

    公开(公告)日:2011-11-29

    申请号:US10464168

    申请日:2003-06-17

    Applicant: David Lawrence

    Inventor: David Lawrence

    Abstract: A computerized method and system for managing risk associated with a Hedge Fund is disclosed. Information relating to Hedge Funds is gathered and stored as data in preparation for a risk inquiry search relating to a Hedge Fund. Documents and sources of information can also be stored. A subscriber, such as a Financial Institution, can submit a Hedge Fund descriptor for which a risk inquiry search can be performed. The risk assessment or inquiry search can include data retrieved resultant to augmented retrieval methods. Scrubbed data as well as augmented data can be transmitted from a risk management clearinghouse to a subscriber or to a proprietary risk system utilized by a subscriber, such as a risk management system maintained in-house. Risk inquiry searches can be automated and made a part of standard operating procedure for any transaction conducted by the subscriber in which a Hedge Fund is involved.

    Abstract translation: 披露了一种用于管理与对冲基金有关的风险的计算机化方法和系统。 收集和存储与对冲基金相关的信息,作为数据,准备与对冲基金相关的风险查询。 文件和信息来源也可以存储。 诸如金融机构的订户可以提交对冲基金描述符,可以对其进行风险查询搜索。 风险评估或查询搜索可以包括数据检索结果以增强检索方法。 洗涤数据以及增强数据可以从风险管理清算站传送到用户或用户所使用的专有风险系统,例如内部维护的风险管理系统。 风险查询搜索可以自动化,并作为涉及对冲基金的用户进行的任何交易的标准操作程序的一部分。

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