公开(公告)号：US09382549B2

公开(公告)日：2016-07-05

申请号：US13757536

申请日：2013-02-01

Applicant: DOW AGROSCIENCES LLC

Inventor： Justin M Lira ,  Robert Cicchillo ,  Carla N Yerkes ,  Andrew E Robinson

IPC: C12N15/82 ,  A01H5/10 ,  C07K14/415 ,  C12N9/96 ,  C12N9/10

CPC classification number: C12N9/1092 ,  A01N57/20 ,  C07K14/415 ,  C07K2319/08 ,  C12N9/0069 ,  C12N9/0071 ,  C12N9/1085 ,  C12N9/96 ,  C12N15/62 ,  C12N15/8205 ,  C12N15/8209 ,  C12N15/8214 ,  C12N15/8221 ,  C12N15/8241 ,  C12N15/8245 ,  C12N15/8247 ,  C12N15/8274 ,  C12N15/8275 ,  C12N15/8281 ,  C12N15/8283 ,  C12N15/8286 ,  C12Y113/00 ,  C12Y114/11 ,  C12Y205/01019 ,  Y02A40/162

Abstract: The present disclosure relates to certain polypeptides derived from prokaryotic DGT enzymes, and nucleic acids useful in encoding the same, for example, novel polypeptides involved in metabolism of N-(phosphonomethyl) glycine, and nucleic acids encoding such polypeptides. In some examples, such a polypeptide confers (or increases) tolerance to glyphosate in a plant cell wherein the polypeptide is heterologously expressed, for example, without adversely affecting the binding of EPSP synthase with its natural substrate, phosphoenolpyruvate (PEP).

Abstract translation: 本公开内容涉及衍生自原核DGT酶的某些多肽，以及可用于编码它们的核酸，例如涉及N-（膦酰基甲基）甘氨酸代谢的新型多肽和编码此类多肽的核酸。 在一些实例中，这样的多肽赋予（或增加）在植物细胞中对草甘膦的耐受性，其中多肽被异源表达，例如不会不利地影响EPSP合酶与其天然底物磷酸烯醇丙酮酸（PEP）的结合。

公开(公告)号：US09493781B2

公开(公告)日：2016-11-15

申请号：US13757613

申请日：2013-02-01

Applicant: DOW AGROSCIENCES LLC

Inventor： Justin M Lira ,  Robert Cicchillo ,  Carla N Yerkes ,  Andrew E Robinson

IPC: C12N15/82 ,  C07K14/415 ,  C12N9/96 ,  C12N9/10

CPC classification number: C12N9/1092 ,  A01N57/20 ,  C07K14/415 ,  C07K2319/08 ,  C12N9/0069 ,  C12N9/0071 ,  C12N9/1085 ,  C12N9/96 ,  C12N15/62 ,  C12N15/8205 ,  C12N15/8209 ,  C12N15/8214 ,  C12N15/8221 ,  C12N15/8241 ,  C12N15/8245 ,  C12N15/8247 ,  C12N15/8274 ,  C12N15/8275 ,  C12N15/8281 ,  C12N15/8283 ,  C12N15/8286 ,  C12Y113/00 ,  C12Y114/11 ,  C12Y205/01019 ,  Y02A40/162

Abstract: This disclosure concerns compositions and methods for targeting peptides, polypeptides, and proteins to plastids of plastid-containing cells. In some embodiments, the disclosure concerns chloroplast transit peptides that may direct a polypeptide to a plastid, and nucleic acid molecules encoding the same. In some embodiments, the disclosure concerns methods for producing a transgenic plant material (e.g., a transgenic plant) comprising a chloroplast transit peptide, as well as plant materials produced by such methods, and plant commodity products produced therefrom.

Abstract translation: 本公开涉及将肽，多肽和蛋白质靶向含质体细胞的质体的组合物和方法。 在一些实施方案中，本公开涉及可将多肽引导至质体的叶绿体转运肽以及编码其的核酸分子。 在一些实施方案中，本公开涉及用于生产包含叶绿体转运肽的转基因植物材料（例如，转基因植物）的方法以及由这些方法生产的植物材料以及由其生产的植物商品。

公开(公告)号：US09506077B2

公开(公告)日：2016-11-29

申请号：US13757639

申请日：2013-02-01

Applicant: DOW AGROSCIENCES LLC

Inventor： Justin M Lira ,  Robert Cicchillo ,  Carla N Yerkes ,  Andrew E Robinson

IPC: C12N15/82 ,  C07K14/415 ,  C12N9/96 ,  C12N9/10

CPC classification number: C12N9/1092 ,  A01N57/20 ,  C07K14/415 ,  C07K2319/08 ,  C12N9/0069 ,  C12N9/0071 ,  C12N9/1085 ,  C12N9/96 ,  C12N15/62 ,  C12N15/8205 ,  C12N15/8209 ,  C12N15/8214 ,  C12N15/8221 ,  C12N15/8241 ,  C12N15/8245 ,  C12N15/8247 ,  C12N15/8274 ,  C12N15/8275 ,  C12N15/8281 ,  C12N15/8283 ,  C12N15/8286 ,  C12Y113/00 ,  C12Y114/11 ,  C12Y205/01019 ,  Y02A40/162

Abstract: This disclosure concerns compositions and methods for targeting peptides, polypeptides, and proteins to plastids of plastid-containing cells. In some embodiments, the disclosure concerns chloroplast transit peptides that may direct a polypeptide to a plastid, and nucleic acid molecules encoding the same. In some embodiments, the disclosure concerns methods for producing a transgenic plant material (e.g., a transgenic plant) comprising a chloroplast transit peptide, as well as plant materials produced by such methods, and plant commodity products produced therefrom.

Abstract translation: 本公开涉及将肽，多肽和蛋白质靶向含质体细胞的质体的组合物和方法。 在一些实施方案中，本公开涉及可将多肽引导至质体的叶绿体转运肽以及编码其的核酸分子。 在一些实施方案中，本公开涉及用于生产包含叶绿体转运肽的转基因植物材料（例如，转基因植物）的方法以及由这些方法生产的植物材料以及由其生产的植物商品。

公开(公告)号：US10577619B2

公开(公告)日：2020-03-03

申请号：US15198740

申请日：2016-06-30

Applicant: Dow AgroSciences LLC

Inventor： Justin M. Lira ,  Robert Cicchillo ,  Carla N Yerkes ,  Andrew E Robinson

IPC: C12N15/82 ,  C07K14/415 ,  A01N57/20 ,  C12N9/02 ,  C12N9/10 ,  C12N9/96 ,  C12N15/62

Abstract: The present disclosure relates to certain polypeptides derived from prokaryotic DGT enzymes, and nucleic acids useful in encoding the same.