公开(公告)号：US08597187B2

公开(公告)日：2013-12-03

申请号：US12484971

申请日：2009-06-15

Applicant: Richard Lee Nuccitelli ,  Pamela Nuccitelli ,  Suman Narsing ,  Brian Athos ,  Saleh Sheikh

Inventor： Richard Lee Nuccitelli ,  Pamela Nuccitelli ,  Suman Narsing ,  Brian Athos ,  Saleh Sheikh

IPC: A61B5/103

CPC classification number: A61B5/442 ,  A61B5/0051 ,  A61B5/053 ,  A61B5/063 ,  A61B5/6843 ,  A61B5/6844 ,  A61B5/6886

Abstract: The present invention provides a hand-held, noninvasive diagnostic device for measuring the electric fields in mammalian skin and other epithelial structures. The device includes an outer housing that contacts the skin, providing stability and allowing the device to move along with minor movement of the skin. Recessed within the outer housing is a probe that acts as a sensor to measure the electric field in the skin through an aperture in the bottom surface of the outer housing. By applying a series of known voltages while the probe is vibrating, the skin's local surface potential can be measured and the lateral electric field can be calculated from the spatial distribution of surface potential measurements. Active feedback is used to maintain a constant distance between the probe and the skin surface.

Abstract translation: 本发明提供了用于测量哺乳动物皮肤和其它上皮结构中的电场的手持式无创诊断装置。 该装置包括接触皮肤的外壳，提供稳定性并允许装置随着皮肤的轻微移动而移动。 嵌入在外壳内部的探头是用作传感器的探针，用于通过外壳底面的孔来测量皮肤中的电场。 通过在探头振动时应用一系列已知的电压，可以测量皮肤的局部表面电位，并可以从表面电位测量的空间分布计算横向电场。 主动反馈用于保持探头与皮肤表面之间的恒定距离。

公开(公告)号：US20100016686A1

公开(公告)日：2010-01-21

申请号：US12484971

申请日：2009-06-15

Applicant: Richard Lee NUCCITELLI ,  Pamela NUCCITELLI ,  Suman NARSING ,  Brian ATHOS ,  Saleh SHEIKH

Inventor： Richard Lee NUCCITELLI ,  Pamela NUCCITELLI ,  Suman NARSING ,  Brian ATHOS ,  Saleh SHEIKH

IPC: A61B5/04

CPC classification number: A61B5/442 ,  A61B5/0051 ,  A61B5/053 ,  A61B5/063 ,  A61B5/6843 ,  A61B5/6844 ,  A61B5/6886

Abstract: The present invention provides a hand-held, noninvasive diagnostic device for measuring the electric fields in mammalian skin and other epithelial structures. The device includes an outer housing that contacts the skin, providing stability and allowing the device to move along with minor movement of the skin. Recessed within the outer housing is a probe that acts as a sensor to measure the electric field in the skin through an aperture in the bottom surface of the outer housing. By applying a series of known voltages while the probe is vibrating, the skin's local surface potential can be measured and the lateral electric field can be calculated from the spatial distribution of surface potential measurements. Active feedback is used to maintain a constant distance between the probe and the skin surface.

Abstract translation: 本发明提供了用于测量哺乳动物皮肤和其它上皮结构中的电场的手持式无创诊断装置。 该装置包括接触皮肤的外壳，提供稳定性并允许装置随着皮肤的轻微移动而移动。 嵌入在外壳内部的探头是用作传感器的探针，用于通过外壳底面的孔来测量皮肤中的电场。 通过在探头振动时应用一系列已知的电压，可以测量皮肤的局部表面电位，并可以从表面电位测量的空间分布计算横向电场。 主动反馈用于保持探头与皮肤表面之间的恒定距离。

公开(公告)号：US20090281411A1

公开(公告)日：2009-11-12

申请号：US12117598

申请日：2008-05-08

Applicant: Richard Nuccitelli ,  Pamela Nuccitelli ,  Shr-Kai Liau ,  Uwe F. Pliquett ,  Changyi Li ,  Suman Narsing ,  Brian Athos ,  Saleh Sheikh

Inventor： Richard Nuccitelli ,  Pamela Nuccitelli ,  Shr-Kai Liau ,  Uwe F. Pliquett ,  Changyi Li ,  Suman Narsing ,  Brian Athos ,  Saleh Sheikh

IPC: A61B5/05

CPC classification number: A61B5/444 ,  A61B5/0051 ,  A61B5/04 ,  A61B5/442 ,  A61B5/6844 ,  A61B2560/04 ,  A61B2562/0214

Abstract: The present invention provides a hand-held, noninvasive diagnostic device for measuring the electric fields in mammalian skin and other epithelial structures. The device includes an outer housing that contacts the skin, providing stability and allowing the device to move along with minor movement of the skin. Recessed within the outer housing is a probe that acts as a sensor to measure the electric field in the skin through an aperture in the bottom surface of the outer housing. By applying a series of known voltages while the probe is vibrating, the skin's local surface potential can be measured and the lateral electric field can be calculated from the spatial distribution of surface potential measurements. Active feedback is used to maintain a constant distance between the probe and the skin surface.

Abstract translation: 本发明提供了用于测量哺乳动物皮肤和其它上皮结构中的电场的手持式无创诊断装置。 该装置包括接触皮肤的外壳，提供稳定性并允许装置随着皮肤的轻微移动而移动。 嵌入在外壳内部的探头是用作传感器的探针，用于通过外壳底面的孔来测量皮肤中的电场。 通过在探头振动时应用一系列已知的电压，可以测量皮肤的局部表面电位，并可以从表面电位测量的空间分布计算横向电场。 主动反馈用于保持探头与皮肤表面之间的恒定距离。

公开(公告)号：US08694088B2

公开(公告)日：2014-04-08

申请号：US12117598

申请日：2008-05-08

Applicant: Richard Nuccitelli ,  Pamela Nuccitelli ,  Shr-Kai Liau ,  Uwe F. Pliquett ,  Changyi Li ,  Suman Narsing ,  Brian Athos ,  Saleh Sheikh

Inventor： Richard Nuccitelli ,  Pamela Nuccitelli ,  Shr-Kai Liau ,  Uwe F. Pliquett ,  Changyi Li ,  Suman Narsing ,  Brian Athos ,  Saleh Sheikh

IPC: A61B5/00

CPC classification number: A61B5/444 ,  A61B5/0051 ,  A61B5/04 ,  A61B5/442 ,  A61B5/6844 ,  A61B2560/04 ,  A61B2562/0214

Abstract: The present invention provides a hand-held, noninvasive diagnostic device for measuring the electric fields in mammalian skin and other epithelial structures. The device includes an outer housing that contacts the skin, providing stability and allowing the device to move along with minor movement of the skin. Recessed within the outer housing is a probe that acts as a sensor to measure the electric field in the skin through an aperture in the bottom surface of the outer housing. By applying a series of known voltages while the probe is vibrating, the skin's local surface potential can be measured and the lateral electric field can be calculated from the spatial distribution of surface potential measurements. Active feedback is used to maintain a constant distance between the probe and the skin surface.

Abstract translation: 本发明提供了用于测量哺乳动物皮肤和其它上皮结构中的电场的手持式无创诊断装置。 该装置包括接触皮肤的外壳，提供稳定性并允许装置随着皮肤的轻微移动而移动。 嵌入在外壳内部的探头是用作传感器的探针，用于通过外壳底面的孔来测量皮肤中的电场。 通过在探头振动时应用一系列已知的电压，可以测量皮肤的局部表面电位，并可以从表面电位测量的空间分布计算横向电场。 主动反馈用于保持探头与皮肤表面之间的恒定距离。