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公开(公告)号：US07419498B2
公开(公告)日：2008-09-02
申请号：US10944512
申请日：2004-09-17
Applicant: Steven Opolski , Sean Forde
Inventor： Steven Opolski , Sean Forde
CPC classification number: A61B17/0057 , A61B17/12022 , A61B17/12122 , A61B17/12131 , A61B2017/00473 , A61B2017/00575 , A61B2017/00592 , A61B2017/00606 , A61B2017/00623 , A61B2017/0472 , A61B2017/0475
Abstract: A medical delivery system for delivering or retrieving a medical implant. In one embodiment, the medical delivery system includes a tube having a lumen; an implant; and a suture releasably joined to the implant, the suture comprising a first end, a second end, and a releasable knot, wherein tension applied to the first end of the suture collapses at least a portion of the implant for introduction into the tubular lumen and tension applied to the second end of the suture releases the implant.
Abstract translation: 用于输送或取回医用植入物的医疗输送系统。 在一个实施例中，医疗输送系统包括具有内腔的管; 植入物 以及可释放地接合到植入物的缝合线，缝合线包括第一端，第二端和可释放结，其中施加到缝合线的第一端的张力塌陷至少一部分植入物以引入管状管腔， 施加到缝合线第二端的张力释放植入物。
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公开(公告)号：US20070167981A1
公开(公告)日：2007-07-19
申请号：US11644373
申请日：2006-12-21
Applicant: Steven Opolski , Sean Forde , Stephanie Kladakis , David Callaghan
Inventor： Steven Opolski , Sean Forde , Stephanie Kladakis , David Callaghan
IPC: A61B17/08
CPC classification number: A61B17/1215 , A61B17/0057 , A61B2017/00004 , A61B2017/00575 , A61B2017/00592 , A61B2017/00606 , A61B2017/00619 , A61B2017/00623
Abstract: Devices and techniques for modifying and maintaining a configuration of an occlusion device for the closure of physical anomalies, such as an atrial septal defect, a patent foramen ovale (PFO), and other septal and vascular defects are described. The devices and techniques relate particularly to, but are not limited to, modifying and maintaining a configuration of a PFO occluder made from a polymer tube. The proximal portion of a catch member may be provided with one or more protrusions, or arms, or bump or other raised element for securing the occluder in a partial or fully deployed configuration, either temporarily or permanently.
Abstract translation: 描述了用于修改和保持用于闭合物理异常的闭塞装置的构造的装置和技术，例如房间隔缺损，卵圆孔卵孔（PFO）以及其它间隔和血管缺陷。 所述装置和技术特别涉及但不限于修改和维持由聚合物管制成的PFO封堵器的构造。 捕获构件的近侧部分可以设置有一个或多个突起，或臂或凸起或其它凸起元件，用于将闭塞器临时或永久地部分地或完全展开的构造固定。
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公开(公告)号：US07232421B1
公开(公告)日：2007-06-19
申请号：US09743726
申请日：2000-05-12
Applicant: Richard A. Gambale , Chirag B. Shah , Michael F. Weiser , Stephen J. Forcucci , Sean Forde
Inventor： Richard A. Gambale , Chirag B. Shah , Michael F. Weiser , Stephen J. Forcucci , Sean Forde
IPC: A61M31/00
CPC classification number: A61M37/0069 , A61B17/3468 , A61B2017/00247 , A61B2018/00392
Abstract: The present invention provides a system for delivering a therapeutic agent into tissue in combination with an implant device (2). Preferably the therapeutic substance is contained within a pellet form (14) that is deliverable into the interior of the device (2) after it has been implanted. In a preferred embodiment the implant device (2) comprises a flexible coiled spring body, the coils (4) of which have the proper diameter and spacing to contain the pellet (14) within the interior of the device (2) to contact the therapeutic agent. In treatment of ischemic tissue such as that of the myocardium of the heart, the mechanical irritation of the tissue caused by the implanted device (2) can help to provide an angiogenic effect. Additionally, the cavity (18) provided by the interior of the device (2) permits blood to pool around the pellet (14) and mix with the therapeutic agent. Several delivery systems have provided for delivering the implant and pellet (14) sequentially or simultaneously.
Abstract translation: 本发明提供了一种用于将治疗剂与植入装置（2）组合递送到组织中的系统。 优选地，治疗物质包含在颗粒形式（14）中，其在植入之后可输送到装置（2）的内部。 在优选实施例中，植入装置（2）包括柔性螺旋弹簧体，其线圈（4）具有适当的直径和间隔，以在装置（2）内部容纳颗粒（14）以接触治疗 代理商 在诸如心脏心肌的缺血组织的治疗中，由植入装置（2）引起的组织的机械刺激可以有助于提供血管生成作用。 此外，由装置（2）的内部提供的空腔（18）允许血液围绕丸粒（14）聚集并与治疗剂混合。 已经提供了几个递送系统来顺序地或同时地递送植入物和颗粒（14）。
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公开(公告)号：US20070066864A1
公开(公告)日：2007-03-22
申请号：US11516144
申请日：2006-09-06
Applicant: Sean Forde
Inventor： Sean Forde
IPC: A61F5/00
CPC classification number: A61B18/00 , A61B17/12022 , A61B18/1492 , A61B18/1815 , A61B18/22 , A61B18/24 , A61B2017/00575 , A61B2018/00291 , A61B2018/00351 , A61B2018/1861
Abstract: The invention generally relates to devices and methods for treating cardiac tissue, including percutaneous closure of cardiac openings such as a patent foramen ovale (PFO) and obliteration of the cardiac cul-de-sacs. The invention includes a device having at least one elongated member. The elongated member has a first material and a second material interwoven with at least a portion of the first material. The second material is capable of transferring energy to tissue in need of treatment.
Abstract translation: 本发明一般涉及用于治疗心脏组织的装置和方法，包括心脏开放的经皮闭合，例如卵圆孔（PFO）和闭塞心脏死囊。 本发明包括具有至少一个细长构件的装置。 细长构件具有与第一材料的至少一部分交织的第一材料和第二材料。 第二种材料能够将能量转移到需要治疗的组织中。
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公开(公告)号：US20050004558A1
公开(公告)日：2005-01-06
申请号：US10899368
申请日：2004-07-26
Applicant: Richard Gambale , Stephen Forcucci , Michael Weiser , Richard Choh , Sean Forde
Inventor： Richard Gambale , Stephen Forcucci , Michael Weiser , Richard Choh , Sean Forde
CPC classification number: A61F2/94 , A61F2/2493 , A61F2230/0091 , A61F2250/0067
Abstract: Implants and associated delivery systems for promoting angiogenesis in ischemic tissue are provided. The implants may be delivered percutaneously, thoracically or surgically and are particularly well suited for implantation into the myocardium of the heart. The implants are configured to be flexible so that they compress and expand with corresponding movement of the surrounding tissue into which they are implanted. The flow of blood into the implant and pooling of the blood in and around the implant leads to thrombosis and fibrin growth, a healing process that leads to angiogenesis in the tissue surrounding the implant. Additionally, the implants may contain an angiogenic substance or a thrombus of blood, preloaded or injected after implantation to aid in initiating angiogenesis.
Abstract translation: 提供了用于促进缺血组织中血管生成的植入物和相关递送系统。 植入物可以经皮，胸部或手术递送，并且特别适合于植入心脏的心肌。 植入物被构造成具有柔性的，使得它们随着植入其中的周围组织的相应运动而压缩和扩张。 血液进入植入物的流动以及血液在植入物中和周围的汇集导致血栓形成和纤维蛋白生长，这是导致植入物周围组织血管生成的愈合过程。 此外，植入物可能含有血管生成物质或血栓，预先加载或在植入后注射以帮助起始血管发生。
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Patent Agency Ranking
公开(公告)号：US20170333104A1
公开(公告)日：2017-11-23
申请号：US15158698
申请日：2016-05-19
Applicant: Sean Forde , Sean Arthur McDermott , Brian Hanley
Inventor： Sean Forde , Sean Arthur McDermott , Brian Hanley
CPC classification number: A61B18/02 , A61B2017/00469 , A61B2017/00477 , A61B2018/00166 , A61B2018/00172 , A61B2018/00196 , A61B2018/00541 , A61B2018/00738 , A61B2018/00982 , A61B2018/0212 , A61B2090/034 , A61B2090/062 , A61B2090/0811
Abstract: The present disclosure pertains to devices and methods for diagnosis and treatment of biological tissue in which the tissue is accessed by a catheter through a working channel of an endoscope and in which the degree of extension of a distal tip of the catheter beyond a distal tip of the endoscope is controlled.
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公开(公告)号：US20100312236A1
公开(公告)日：2010-12-09
申请号：US12856654
申请日：2010-08-15
Applicant: Sean Forde , James Scutti , David J. Callaghan , Eric Glaser , Carol Devellian , Steven Opolski
Inventor： Sean Forde , James Scutti , David J. Callaghan , Eric Glaser , Carol Devellian , Steven Opolski
CPC classification number: A61B18/1492 , A61B2017/00575 , A61B2017/00592 , A61B2017/00606 , A61B2018/00351 , A61B2018/1435
Abstract: The present invention provides systems and methods for occluding or closing a patent foramen ovale of a patient (PFO). The invention includes a catheter carrying an energy delivery element. The catheter introduces the energy delivery element into the patent foramen ovale of a patient's heart. Once appropriately positioned, the energy delivery element applies energy, such as radiofrequency energy, to the tissues surrounding the patent foramen ovale. The application of energy causes the tissues to join together, occluding the patent foramen ovale. The energy delivery element may be removable or permanently implanted in the patent foramen ovale.
Abstract translation: 本发明提供了用于闭塞或闭合患者（PFO）的卵孔专利的系统和方法。 本发明包括承载能量输送元件的导管。 导管将能量递送元件引入患者心脏的卵孔中。 一旦适当定位，能量传递元件将能量（例如射频能量）施加到卵孔卵孔周围的组织。 能量的应用导致组织结合在一起，阻塞卵巢卵泡的专利。 能量输送元件可以是可移除的或永久地植入卵孔的专利。
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公开(公告)号：US07473260B2
公开(公告)日：2009-01-06
申请号：US10862939
申请日：2004-06-08
Applicant: Steven Opolski , Sean Forde
Inventor： Steven Opolski , Sean Forde
IPC: A61B17/04
CPC classification number: A61B17/0467 , A61B17/0469 , A61B17/320016 , A61B2017/00292 , A61B2017/00575 , A61B2017/00606 , A61B2017/00623 , A61B2017/2905
Abstract: An apparatus for cutting a suture. In one embodiment the suture cutting apparatus includes a distal cutting end and a proximal control end. The apparatus also includes a first tube defining a lumen, and a second tube located and movable within the lumen of the first tube. The second tube defines a lumen and includes a lever arm pivotably attached at the distal cutting end of the apparatus. The lever arm has a cutting edge that is held away from the longitudinal axis of the second tube when the lever arm is located within the first tube, and is biased toward the longitudinal axis of second tube when the lever arm is outside of the first tube.
Abstract translation: 一种用于切割缝合线的装置。 在一个实施例中，缝合线切割设备包括远端切割端和近端控制端。 该装置还包括限定内腔的第一管和位于第一管的内腔内且可移动的第二管。 第二管限定内腔并且包括可枢转地附接在装置的远端切割端处的杠杆臂。 杠杆臂具有当杆臂位于第一管内时远离第二管的纵向轴线保持的切割边缘，并且当杠杆臂位于第一管的外部时被朝向第二管的纵向轴线偏压 。
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公开(公告)号：US20050060019A1
公开(公告)日：2005-03-17
申请号：US10951735
申请日：2004-09-28
Applicant: Richard Gambale , Stephen Forcucci , Michael Weiser , Sean Forde
Inventor： Richard Gambale , Stephen Forcucci , Michael Weiser , Sean Forde
CPC classification number: A61F2/88 , A61F2/06 , A61F2/2493 , A61F2220/0016 , A61F2250/0067
Abstract: The present invention provides a system (178) for delivering a therapeutic agent in combination with an implantable device (2) to maximize a therapeutic benefit offered by each. Preferably, the therapeutic agent is contained within a solid matrix form such as a pellet or gel to facilitate its handling and to regulate its rate of dissipation into the tissue after delivery. The implant device (2) is specially configured to receive and retain the matrix but permit blood to interact with the matrix so that the agent can be released to the blood in and around the device and the surrounding tissue. A delivery system (178) comprises an implant delivery device having an obturator (180) capable of piercing the tissue and an agent matrix delivery device (210) to place a matrix form, such as a pellet, into the interior of the implant (2) after it has been implanted. Preferably, the implant delivery device (180) and the matrix delivery device (210) are contained in one apparatus to facilitate delivery of the pellet into the embedded implant. The present invention is useful for treating tissue in any area of the body, especially ischemic tissue experiencing reduced blood flow. The present devices and methods are especially useful for treatment of ischemia of the myocardium. In treatment of the myocardium, the present implant device and matrix combination may be delivered surgically through the epicardium of the heart.
Abstract translation: 本发明提供了一种用于将治疗剂与可植入装置（2）组合递送以最大化由每个提供的治疗益处的系统（178）。 优选地，治疗剂包含在固体基质形式例如丸粒或凝胶中，以促进其处理并调节其在分娩后向组织中的耗散速率。 植入装置（2）被特别地构造成接收和保持基质，但允许血液与基质相互作用，使得试剂可以释放到装置周围的组织和周围的组织中和周围。 递送系统（178）包括植入物递送装置，其具有能够刺穿组织的闭孔器（180）和药剂矩阵输送装置（210），以将诸如颗粒的矩阵形式放置在植入物（2）的内部 ）植入后。 优选地，植入物递送装置（180）和基质递送装置（210）被包含在一个装置中以便于将颗粒递送到嵌入的植入物中。 本发明可用于治疗身体的任何区域中的组织，特别是经历血流减少的缺血组织。 本发明的装置和方法对于治疗心肌缺血特别有用。 在心肌的治疗中，本发明的植入装置和基质组合可以通过心脏的心外膜手术递送。
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公开(公告)号：US09259267B2
公开(公告)日：2016-02-16
申请号：US11516144
申请日：2006-09-06
Applicant: Sean Forde
Inventor： Sean Forde
CPC classification number: A61B18/00 , A61B17/12022 , A61B18/1492 , A61B18/1815 , A61B18/22 , A61B18/24 , A61B2017/00575 , A61B2018/00291 , A61B2018/00351 , A61B2018/1861
Abstract: The invention generally relates to devices and methods for treating cardiac tissue, including percutaneous closure of cardiac openings such as a patent foramen ovale (PFO) and obliteration of the cardiac cul-de-sacs. The invention includes a device having at least one elongated member. The elongated member has a first material and a second material interwoven with at least a portion of the first material. The second material is capable of transferring energy to tissue in need of treatment.
Abstract translation: 本发明一般涉及用于治疗心脏组织的装置和方法，包括心脏开放的经皮闭合，例如卵圆孔（PFO）和闭塞心脏死囊。 本发明包括具有至少一个细长构件的装置。 细长构件具有与第一材料的至少一部分交织的第一材料和第二材料。 第二种材料能够将能量转移到需要治疗的组织中。
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