Invention Grant
- Patent Title: Genes differentially expressed in breast cancer
- Patent Title (中): 在乳腺癌中差异表达的基因
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Application No.: US11450251Application Date: 2006-06-08
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Publication No.: US08236928B2Publication Date: 2012-08-07
- Inventor: Joerg Kaufmann , Greg Harrowe , Christoph Reinhard , Sanmao Kang
- Applicant: Joerg Kaufmann , Greg Harrowe , Christoph Reinhard , Sanmao Kang
- Applicant Address: US CA Emeryville
- Assignee: Novartis Vaccines and Diagnostics, Inc.
- Current Assignee: Novartis Vaccines and Diagnostics, Inc.
- Current Assignee Address: US CA Emeryville
- Agent Mei Hong; Patricia Tsao
- Main IPC: C07K14/00
- IPC: C07K14/00 ; C07K17/00 ; C12P19/42 ; C12P29/00
Abstract:
A polynucleotide sequence as shown in SEQ ID NO:1 is associated with metastatic potential of cancer cells, especially breast cancer cells. Methods are provided for determining the risk of metastasis of a tumor, by determining whether a tissue sample from a tumor expresses a polypeptide or mRNA encoded by a polynucleotide as shown in SEQ ID NO:1. Also provided are therapeutic methods and compositions.
Public/Granted literature
- US20060216748A1 Genes differentially expressed in breast cancer Public/Granted day:2006-09-28
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