Invention Grant
US08236300B2 In vivo and ex vivo gene transfer into renal tissue using gutless adenovirus vectors
有权
使用无菌腺病毒载体将体内和离体基因转移到肾组织中
- Patent Title: In vivo and ex vivo gene transfer into renal tissue using gutless adenovirus vectors
- Patent Title (中): 使用无菌腺病毒载体将体内和离体基因转移到肾组织中
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Application No.: US13023322Application Date: 2011-02-08
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Publication No.: US08236300B2Publication Date: 2012-08-07
- Inventor: Lakshman R. Sehgal , Jonathan Wong
- Applicant: Lakshman R. Sehgal , Jonathan Wong
- Applicant Address: US IL Chicago
- Assignee: Biovec, LLC
- Current Assignee: Biovec, LLC
- Current Assignee Address: US IL Chicago
- Agency: Andrews Kurth, LLP
- Agent Ping Wang, Esq.
- Main IPC: A01K63/00
- IPC: A01K63/00 ; A61K39/325 ; C07H21/04
Abstract:
A method for treating a renal disease in a subject is disclosed. The method includes administering into a kidney of the subject with an effective amount of a gutless adenoviral vector containing a polynucleotide encoding a therapeutic agent. The gutless adenoviral vector contains the nucleotide sequence of SEQ ID NO:13 or SEQ ID NO:15 and expresses the therapeutic agent in a kidney tissue of the subject.
Public/Granted literature
- US20110196023A1 IN VIVO AND EX VIVO GENE TRANSFER INTO RENAL TISSUE USING GUTLESS ADENOVIRUS VECTORS Public/Granted day:2011-08-11
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