Invention Grant
- Patent Title: Methods for characterizing DNA sequence composition in a genome
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Application No.: US16598341Application Date: 2019-10-10
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Publication No.: US10941436B2Publication Date: 2021-03-09
- Inventor: Mary Beatty , Kevin Hayes , Jenna Hoffman , Haining Lin , Gina Marie Zastrow-Hayes
- Applicant: PIONEER HI-BRED INTERNATIONAL, INC.
- Applicant Address: US IA Johnston
- Assignee: PIONEER HI-BRED INTERNATIONAL, INC.
- Current Assignee: PIONEER HI-BRED INTERNATIONAL, INC.
- Current Assignee Address: US IA Johnston
- Main IPC: C12P19/34
- IPC: C12P19/34 ; C12Q1/6806 ; C12Q1/6869 ; C12Q1/6895
Abstract:
Methods for the high-throughput analysis of transgenic events are herein disclosed. The methods use libraries of sheared genomic DNA ligated to specialized adapters and pooled for sequence analysis and comparison to known genomic and insert sequence. The method finds use in detecting characterizing insertion site, transgene integrity, and transgene copy number.
Public/Granted literature
- US20200032320A1 METHODS FOR CHARACTERIZING DNA SEQUENCE COMPOSITION IN A GENOME Public/Granted day:2020-01-30
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