Invention Grant
- Patent Title: Nucleotide sequence exclusion enrichment by droplet sorting (NEEDLS)
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Application No.: US15317050Application Date: 2015-06-11
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Publication No.: US10704080B2Publication Date: 2020-07-07
- Inventor: Marie Just Mikkelsen , Thomas Kvist
- Applicant: Samplix ApS
- Applicant Address: DK Herlev
- Assignee: Samplix ApS
- Current Assignee: Samplix ApS
- Current Assignee Address: DK Herlev
- Agency: Casimir Jones, S.C.
- Agent Lisa V. Mueller
- Priority: com.zzzhc.datahub.patent.etl.us.BibliographicData$PriorityClaim@63e49d60
- International Application: PCT/EP2015/063076 WO 20150611
- International Announcement: WO2015/189336 WO 20151217
- Main IPC: C12Q1/68
- IPC: C12Q1/68 ; C07H21/00 ; C12Q1/6806 ; C12Q1/6848 ; C12Q1/686
Abstract:
The present invention pertains to an in vitro method in which a targeted DNA molecule containing a DNA sequence of interest is enriched by a) general amplification of DNA molecules in a multiple of droplets each containing less than 0.5 target DNA molecule on average (404), b) specific detection of the target DNA molecule in each of the droplets (405), and c) physically selecting droplets containing target DNA molecules (406).
Public/Granted literature
- US20170211127A1 NUCLEOTIDE SEQUENCE EXCLUSION ENRICHMENT BY DROPLET SORTING (NEEDLS) Public/Granted day:2017-07-27
Information query
