Invention Grant
- Patent Title: Highly efficient synthesis of long RNA using reverse direction approach
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Application No.: US15068807Application Date: 2016-03-14
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Publication No.: US10167308B2Publication Date: 2019-01-01
- Inventor: Suresh C Srivastava , Naveen P Srivastava
- Applicant: ChemGenes Corporation
- Applicant Address: US MA Wilmington
- Assignee: ChemGenes Corporation
- Current Assignee: ChemGenes Corporation
- Current Assignee Address: US MA Wilmington
- Agency: Harvest IP Law LLP
- Main IPC: C07H1/00
- IPC: C07H1/00 ; C07H21/02 ; C12Q1/6806 ; C07H21/00
Abstract:
The present invention relates to novel process of reverse 5′→3′ directed synthesis of RNA oligomers in the range of about 100-mer to about 200-mer has been developed and disclosed. Using that method demonstrated high quality RNA synthesis with coupling efficiency approaching 99%.
Public/Granted literature
- US20160200759A1 HIGHLY EFFICIENT SYNTHESIS OF LONG RNA USING REVERSE DIRECTION APPROACH Public/Granted day:2016-07-14
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