The invention provides a mobile phone application power consumption detection method and device. The method comprises the steps that a fully charged mobile phone and a fully charged computer are connected through a USB; in a charge cancellation mode, before an application to be tested is installed in the mobile phone, a first power value after running in a first preset time period is acquired andstored in the computer; the fully charged mobile phone and the fully charged computer are connected through the USB; in a charge cancellation mode, before the application to be tested is installed inthe mobile phone, a second power value after running in a second preset time period is acquired and stored in the computer; and the power consumption of the application to be tested is determined according to the first power value and the second power value. According to the technical scheme, the efficiency and accuracy of power consumption detection of the mobile phone application are improved, and the power consumption detection cost is reduced.