The invention relates to sound speaker boxes, particularly to an electro-acoustic transformation quadruple-wave fused low-pitch speaker box. The quadruple-wave fused low-pitch speaker box comprises two box bodies, which are nested from inside to outside and are independent from each other; each box body is provided with a sound guide pipe and a sound outlet, which are communicated with the ambient atmosphere and conduct sound airflows between the ambient atmosphere and the box body; the second box body is arranged inside the first box body, the four box plates of the second box body are provided with four groups of loudspeakers electrically connected with an audio frequency amplifier, the loudspeakers produce sound in the same phase; the loudspeakers on the opposite box plates are symmetrically arranged. According to the quadruple-wave fused low-pitch speaker box, driven by the audio frequency amplifier, the vibrating diaphragms of the four groups of opposite loudspeakers vibrate to produce four groups of opposite acoustic wave airflows; the four groups of opposite acoustic wave airflows are fused through the two box bodies to form unified acoustic waves, the two sound guide pipes and the two sound outlets issue low-frequency acoustic waves, so that the low-frequency acoustic waves can be strengthened substantially, and the size and the weight of the speaker box can be reduced.