US11136655B2
The present invention provides a heat-resistant alloy and a reaction tube having excellent oxidation resistance, excellent mechanical properties such as tensile ductility, and weldability. A heat-resistant alloy of the present invention comprises, in terms of % by mass, C: 0.35% to 0.7%, Si: more than 0% and 1.5% or less, Mn: more than 0% and 2.0% or less, Cr: 22.0% to 40.0%, Ni: 25.0% to 48.3%, Al: 1.5% to 4.5%, Ti: 0.01% to 0.6%, and the balance being Fe and inevitable impurities, wherein when Pa=−11.1+28.1×C+29.2×Si−0.25×Ni−45.6×Ti, and Ya=−13.75×Al+63.75, Pa
US11136653B2
The present invention relates to a steel material for pressure vessels, offshore structures and the like and, more specifically, to a high-strength steel material having excellent low-temperature strain aging impact properties and a method for manufacturing same.
US11136652B2
An aluminum alloy material comprises: Si: less than 0.2 mass %, Fe: 0.1 to 0.3 mass %, Cu: 1.0 to 2.5 mass %, Mn: 1.0 to 1.6 mass %, and Mg: 0.1 to 1.0 mass %, the balance being Al and incidental impurities. A number density of Al—Mn compound having a circle equivalent diameter of not less than 0.1 μm is not less than 1.0×105 mm−2, and a number density of Al2Cu having a circle equivalent diameter of not less than 0.1 μm is not more than 1.0×105 mm−2.
US11136649B2
A method of casting an article includes forming a melt comprising copper, introducing manganese into the melt to produce a copper-manganese alloy, and casting the copper-manganese alloy in a mold to form the article. The carbon and oxygen contents of the copper-manganese alloy are controlled in order to control the formation of graphite, manganese carbide, and/or manganese oxide particles within the article. Copper-manganese alloys containing carbon are also provided, as well as articles made therefrom in cast or wrought form.
US11136647B2
A method for generating alkali metal in a zero oxidation state includes reacting an alkali metal compound having a —S-M substituent, where M is an alkali metal and S is sulfur, with gold in a zero oxidation state to release the alkali metal in the zero oxidation state. For example, an alkali metal alkylthiolate can be reacted with a gold in a zero oxidation state to release the alkali metal in the zero oxidation state. As another example, an alkali metal sulfide can be reacted with gold in a zero oxidation state to release the alkali metal in the zero oxidation state. The alkali metal may be used in various applications including vapor cells, magnetometers, and magnetic field measurement systems.
US11136640B2
In a heat treatment method for obtaining a bearing ring for an annular roller bearing whose thickness changes in an axial direction, the heat treatment method includes (A) applying a quenching process to a work which is annular, made of high carbon chromium bearing steel, and having a thickness changing in an axial direction, (B) applying a tempering process to the work which is quenched to entirely soak the work in cooling liquid and inductively heat the work in a state that the work is soaked in the cooling liquid, and (C) applying a finishing process to the work which is tempered.
US11136630B2
This disclosure concerns methods and compositions for identifying cotton plants that have a reniform nematode resistance trait. Some embodiments concern molecular markers to identify, select, and/or construct reniform nematode resistant plants and germplasm, or to identify and counter-select relatively susceptible plants. This disclosure also concerns cotton plants comprising a reniform nematode resistance trait that are generated by methods utilizing at least one marker described herein.
US11136629B2
This application describes methods and compositions for detecting and treating vimentin-associated neoplasia. Differential methylation of the vimentin nucleotide sequences has been observed in vimentin-associated neoplasia such as neoplasia of the upper or lower gastrointestinal tract, pancreas, and/or bladder.
US11136627B2
The present invention features a method and kit for isolating microvesicles or extracting microvesicle nucleic acids from a biological sample by using a control particle. The present invention provides control particles that are viruses or virus-like particles, such as bacteriophages, that contain control nucleic acids that can be detected to assess the accuracy, reliability, and efficiency of the microvesicle isolation or nucleic acid extraction steps. The methods described herein may further comprise the analysis of the presence, absence, or level of at least one biomarker associated with a disease or medical condition for diagnosing, prognosing, or monitoring the disease or medical condition.
US11136626B2
This invention provides gene expression profiles useful for diagnosing lacunar stroke and for distinguishing lacunar stroke from non-lacunar stroke.
US11136616B2
Disclosed are compositions and methods for the preparation of RNA libraries for sequencing, gene expression profiling, microarray and other uses and for simplification of the library preparation process. The disclosure provides blocking oligonucleotides which bind to byproduct nucleic acid molecules formed during the ligation of adapters to nucleic acid segments prior to sequencing and inhibit or block amplification of the byproduct nucleic acid molecules in subsequent amplification reactions. Methods for library preparation using blocking oligonucleotides are also provided.
US11136609B2
An object of the present invention is to provide a separation agent for separating a human serum-derived IgG polyclonal antibody. This object is achieved by a separation agent for separating a human serum-derived IgG polyclonal antibody, the separation agent including: a carrier; and a single-chain antibody which has a dissociation constant for a human serum-derived IgG polyclonal antibody of not more than 3.0×10−8 M and which binds to the surface of the carrier via a chemical bond.
US11136606B2
The present invention relates to a method for producing a food product comprising hydrolysed starch, as well as to products obtainable by the method. The method has the advantage of reducing the amount of sugar (i.e. maltose) produced by hydrolysis as compared to conventional methods of starch hydrolysis and present the additional advantage of providing good processability for the food product.
US11136604B2
The present invention relates to a method for producing chiral β-nitro alcohol compounds. The invention relates in particular to an (R)-selective cupin-nitroaldolase, which enantioselectively can catalyze the Henry reaction, wherein an aldehyde or ketone compound is converted to the corresponding β-nitro alcohol compound in the presence of a nitroalkane compound and a cupin-nitroaldolase.
US11136600B2
The present invention relates to a eukaryotic cell that is genetically modified comprising one or more heterologous gene encoding: a) D-glucose-6-phosphate dehydrogenase and/or b) 6-phosphogluconate dehydrogenase; and/or c) glucose dehydrogenase, gluconolactonase and gluconate kinase, wherein a), b) and glucose dehydrogenase in c) are NAD+ dependent.
US11136599B2
Disclosed herein are engineered cleavage half-domains; fusion polypeptides comprising these engineered cleavage half-domains; polynucleotides encoding the engineered cleavage half-domains and fusion proteins; and cells comprising said polynucleotides and/or fusion proteins. Also described are methods of using these polypeptides and polynucleotides, for example for targeted cleavage of a genomic sequence.
US11136583B2
This document provides methods and materials involved in treating cancer. For example, methods and materials for using an inhibitor of UFM1 activity or expression and/or an inhibitor of UFL1 activity or expression to reduce a cancer cell's ability to carry out a DDR, thereby increasing the sensitivity of cancer cells to treatment with a DNA damaging therapy such as radiation or chemotherapy, are provided.
US11136577B2
The present embodiments provide methods, compounds, and compositions useful for inhibiting PMP22 expression and for treating, preventing, or ameliorating a disease associated with PMP22.
US11136575B2
The present invention relates to a library of particles, the library displaying a plurality of different T cell receptors (TCRs), wherein the plurality of TCRs consists essentially of TCRs comprising an alpha chain comprising an alpha chain variable domain and a beta chain comprising a beta chain variable domain and the library comprises more than one TRAV gene product and/or more than one TRBV gene product, wherein the beta chain variable domain does not comprise one or more of a TRBV5-1, 5-3, 5-4, 5-5, 5-6, 5-7 or 5-8 gene product and wherein the plurality of TCRs do not consist essentially of TCRs comprising a TRAV12-2 gene product from a natural repertoire and a TRBV6 gene product from a natural repertoire and TCRs comprising a TRAV21 gene product from a natural repertoire and a TRBV6 gene product from a natural repertoire.
US11136574B2
Disclosed are methods, components, compositions, and kits for preparing and identifying engineered E. coli ribosomes. The E. coli ribosomes may be prepared and identified under a set of defined conditions, such as in the presences of antibiotics, in order to obtain an engineered ribosome that is resistant to the antibiotic.
US11136572B2
The present disclosure provides compositions of matter, methods and instruments for editing nucleic acids in live yeast cells.
US11136565B2
Provided herein are modified Archaeal family B polymerases derived from the Archaeal microorganism Pyrococcus abyssi that exhibit improved incorporation of nucleotide analogues utilized in DNA sequencing.
US11136564B2
The invention relates to modified polymerase enzymes which exhibit improved incorporation of nucleotide analogues bearing substituents at the 3′ position of the sugar moiety that are larger in size than the naturally occurring 3′ hydroxyl group. Also described are methods of using the polymerases to incorporate nucleotides into polynucleotides, particularly in the context of DNA sequencing.
US11136562B2
The present disclosure provides conditionally active, heterodimeric polypeptides. The conditionally active, heterodimeric polypeptides are active in the presence of a dimerizing agent that induces dimerization of the polypeptides of the heterodimer. A conditionally active, heterodimeric polypeptide of the present disclosure is useful in a variety of research and treatment methods, which are also provided.
US11136561B2
The invention relates to a polypeptide for the enzymatic detoxification of zearalenone, said polypeptide being a monooxygenase which converts the keto group in position 7 of zearalenone into an ester group, the monooxygenase in particular being an amino acid sequence selected from the group comprising sequence ID No. 1, 2 and 3 or a functional variant thereof. The functional variant and at least one of the amino acid sequences has a sequence identity of at least 60%, preferably at least 70%, more preferably at least 80% and most preferably 90%.
US11136556B2
The present invention provides various improved systems and methods for obtaining, generating, culturing, and handling cells, such as stem cells (including induced pluripotent stem cells or iPSCs) and differentiated cells, as well as cells and cell panels produced using such systems and methods, and uses of such cells and cell panels.
US11136554B2
The present invention provides methods of reprogramming cells, for example, directly reprogramming a somatic cell of a first cell type into a somatic cell of a second cell type, are described herein. In particular, the present invention generally relates to methods for reprogramming a cell of an endoderm origin to a cell having pancreatic β-cell characteristics. The present invention also relates to an isolated population comprising reprogrammed cells, compositions and their use in the treatment of diabetes mellitus. In particular, the present invention relates to reprogramming a cell of an endoderm origin to a cell having pancreatic β-cell characteristics by increasing the protein expression of at least one transcription factor selected from Pdx1, Ngn3 or MafA in the cell of endoderm origin to reprogram the cell of an endoderm cell to a cell which exhibits at least one or at least two characteristics of an endogenous pancreatic β-cell.
US11136547B2
Provided is a method for inducing mesoderm, comprising a step of bringing pluripotent stem cells into contact with bone morphogenetic protein 4 (BMP4) or CHIR for at least 3 days.
US11136543B1
A compact device for measuring incubation of living cells with molecules attached to superparamagnetic nanoparticles consisting of iron cores by magnetizing the nanoparticles with an external pulsed field, measuring the time dependence of decaying magnetic fields of the nanoparticles as they attach to the cells by a magnetic sensor, extracting number of attached nanoparticles per cell and rate of incubation by mathematical analysis of the magnetic field emitted by the incubating cells versus time.
US11136542B2
A perfusion bioreactor and a method for using the perfusion bioreactor for performing a continuous cell culture are disclosed. The perfusion bioreactor includes an outer vessel having a housing with a gas permeable membrane, an opening and a cavity; an inner vessel within the cavity; and a lid to cover the opening. A porous membrane within the cavity divides the cavity into inner and outer compartments. A fresh media port extends through the outer vessel or the at least one lid to receive a fresh media tube that has an end located in the inner compartment. A spent media port extends through the outer vessel or the at least one lid to receive a spent media tube that has an end located in the outer compartment. A mixer is within the inner compartment, and the porous membrane is attached to an opening within the inner vessel.
US11136541B2
According to the invention, there is provided a parallel bioreactor system, comprising: an oscillator for generating oscillating motion; a plurality of culture vessels mounted on the oscillator, wherein each culture vessel is provided with an inner cavity, the inner cavity comprises a cylindrical portion at the upper part and an inverted truncated conical bottom at the lower part, a cross section of the cylindrical portion is consistent with the cross section of the top of the inverted truncated conical bottom, and the bottom of the cylindrical portion is joined with the top of the inverted truncated conical bottom; disposable culture bags arranged in the inner cavities of the culture vessels and used for accommodating culture solution, wherein each disposable culture bag is provided with a multifunctional cover plate, and the multifunctional cover plate is connected to the top of the culture bag to seal the culture bag, and is provided with a plurality of connection holes leading to interior of the disposable culture bag; and a control system, wherein the control system controls the oscillating motion of the oscillator and parameters of the culture solution in the disposable culture bags.
US11136532B2
The present invention relates to a hand dishwashing detergent composition including a surfactant system and at least one triblock co-polymer of Formula (I): (EO)x-(PO)y-(EO)x wherein each x is independently on average between about 1 and about 40, and y is on average between about 1 and about 15.
US11136530B2
A washing agent, preferably a liquid washing agent, which contains at least one amine oxide together with at least one sugar surfactant. For example, at least one glucamide, preferably a fatty acid-N-alkyl glucamide, and/or at least one alkyl polyglycoside, having improved cleaning performance, in particular against fat-containing stains. The invention also relates to methods for washing textiles using the described washing agents and to the uses thereof.
US11136528B2
A method of reacting castor oil and an alkoxylated glycerin via a transesterification reaction to produce an estolide of castor oil alkoxylate. Compositions comprising an estolide of castor oil alkoxylate and uses thereof.
US11136514B2
The process and apparatus enables purification of a recycle hydrogen gas stream from hydroprocessing biorenewable feedstocks. The recycle gas stream is fed to a methanator reactor to hydrogenate carbon monoxide in the gas stream to water and methane. Other acid gases can be removed by scrubbing preferably upstream of the methanator. Removal of carbon monoxide omits the need for a hydrogen purge stream to avoid carbon monoxide accumulation and enables use of the hydrogen for a downstream hydroisomerization reaction.
US11136509B2
Methods and systems for manufacturing lubrication oils are disclosed. In one embodiment, a method for manufacturing a lubrication oil includes the steps of receiving into an adsorber unit an unconverted oil (UCO) feedstock comprising five and six ring polynuclear aromatic (PNA) compounds and contacting the UCO feedstock with an adsorbent to remove PNA compounds, thereby forming a treated UCO feedstock with a low concentration of five and six ring PNAs.
US11136507B2
A continuous feeding process and device for waste flexible polymer material; wherein the process continuously feeds waste flexible polymer material into a subsequent pyrolysis apparatus following compression, cutting and dispersion; the waste flexible polymer material is pre-treated during compression, cutting and dispersion to achieve continuous sealing feeding, while pyrolysis oil gas preheats and self-lubricates the device; the device used includes a feeding apparatus, a material dispersion apparatus and a screw feeder; the material is compressed, cut and dispersed in the feeding apparatus and the material dispersion apparatus, and then falls into the screw feeder, being preheated and thermally sealed by the pyrolysis oil-gas in the screw feeder; by using such a process, waste flexible polymer material from various sources may be continuously fed for pyrolysis, fully using the temperature of an oil-gas generated in a pyrolysis machine for preheating and device lubrication.
US11136506B2
A polymer having excellent liquid crystal alignment and electrical properties and thus is suitable for use as a liquid crystal alignment agent, a liquid crystal alignment agent including the same, a liquid crystal alignment film formed from the liquid crystal alignment agent, and a liquid crystal display device including the liquid crystal alignment film are provided.
US11136500B2
An object of the present invention is to provide a luminescent particle having an emission maximum wavelength in a long wavelength range of 680 nm or longer and exhibiting a high quantum yield; and a compound having an emission maximum wavelength in a long wavelength range of 680 nm or longer and exhibiting a high quantum yield in the particles. According to the present invention, provided is a luminescent particle containing at least one kind of compound represented by Formula (1) (definitions of substituents in the formula are as set forth in the description) and a particle.
US11136499B2
The invention relates to an aqueous composition comprising a suspension of ZnO particles and a polymer stabiliser containing carboxylic acid functions and carboxylic acid salt functions.
US11136492B2
The invention is directed to polymers that self-crosslink at acidic pH or can be crosslinked by phenolic agents in brine. Such polymers have lower viscosity and can be pumped deep into reservoirs, where they will cross link in situ, thus increasing their viscosity and/or form a gel and blocking thief zones. Methods of making and using such polymers are also provided.
US11136489B2
A cement composition for use in a well that penetrates a subterranean formation comprising: hydrated lime; a silicate; and water, wherein the composition is substantially free of a hydraulic cement. A method of treating a subterranean formation comprising: introducing the cement composition into the subterranean formation; and allowing the cement composition to set.
US11136488B1
The present invention relates to the technical field of oil and gas drilling, and discloses a biodiesel-based constant rheological property drilling fluid containing intelligent temperature responsive polymer, which contains two or more of the following components which are stored in admixture or separately: base oil biodiesel, aqueous phase, emulsifier, organic soil, constant rheological property flow pattern modifier, hydrolysis inhibitor, filtrate reducer and weighting material; the constant rheological property flow pattern modifier is an intelligent temperature responsive polymer, and the polymer contains structural units provided by bis-hydroxyethyl bis-hydroxypropyl stearyl ammonium chloride, ethylene bis-stearamide and dimerized fatty acid. The drilling fluid provided by the present invention has excellent environmental protection property and degradability, and has conventional rheological property, weak gel structure and fluid loss property which are equivalent to those of the conventional oil-based drilling fluid, and also has excellent temperature resistance, CaO compatibility and constant rheological property.
US11136482B2
The invention provides a composition comprising 1,1-difluoroethene (R-1132a), difluoromethane (R-32), 2,3,3,3-tetra-fluoropropene (R-1234yf), optionally carbon dioxide (CO2, R-744), and, optionally, 1,1,2-trifluoroethene (R-1123).
US11136473B2
It is an object of the present invention to provide a coating film capable of realizing satisfactory sliding properties in addition to water- and oil-repellent properties and wear resistance evaluated by a static contact angle, and a coating composition for obtaining the coating film.
The present invention is directed to a fluorine-containing coating film which has a root mean square roughness of less than 3.5 nm and has a perfluoropolyether structure. It is preferred that the coating film has a polysiloxane backbone and further has a structure in which a fluoroalkyl group is directly bonded to a silicon atom of the polysiloxane backbone, and that a sliding angle of 6 μL of a water droplet is 24.3° or less, or a speed of 20 μL of a water droplet sliding on a coating film inclined at 32° is 0.1 cm/second or more.
US11136465B2
An aqueous coating composition having good freeze-thaw stability and providing coatings with good stain resistance.
US11136450B2
The invention relates to the use of chopped fibers in thermoplastic composite compounds, and in particular to thermoplastic fluoropolymer compounds. The fluoropolymer matrix contains thermoplastic fluoropolymers that have been grafted with a carboxylic polar functionality, such as KYNAR ADX® polymer from Arkema. The chopped fiber—grafted fluoropolymer composite has increased tensile and flexural strength compared to fluoropolymer compounds that contain no grafted carboxylic grafted fluoropolymer.
US11136445B2
A compact camera module that contains a generally planar base on which is mounted a lens barrel is provided. The base, barrel, or both are molded from a polymer composition that includes a thermotropic liquid crystalline polymer and a plurality of mineral fibers (also known as “whisker”). The mineral fibers have a median width of from about 1 to about 35 micrometers and constitute from about 5 wt % to about 60 wt % of the polymer composition.
US11136443B2
The invention relates to multi-layer thermoplastic composites, and in particular composites having fluoropolymer in the outer layer and a thermoplastic substrate layer. The fluoropolymer outer layer may either be a layer comprising a majority, and preferably 100 percent fluoropolymer, or may be a blend of a thermoplastic matrix with fluoropolymer at a level of from 5 to 60 weight percent, based on the total weight of all polymers. Especially useful thermoplastic matrices include acrylic polymers, and styrenic polymers, especially styrenic copolymers such as acrylonitrile/styrene/acrylate (ASA), acrylonitrile/butadiene/styrene (ABS) and styrene/acrylonitrile (SAN). While the fluoropolymer may be any fluoropolymer, thermoplastic fluoropolymers, such as polymers and copolymers of polyvinylidene fluoride are especially useful. The improved flame retardant composite of the invention is especially useful in cap layers over plastic substrates, such as for flame-retardant plastic decking, railings, posts, fencing, siding, roofing, and window profiles.
US11136441B2
A polymer film comprising polyvinyl acetal and a laminated glass manufactured using the same are provided. At least one surface of the polymer film has a void volume (Vv) value at a material ratio of 10% ranging from 2 μm3/μm2 to 18 μm3/μm2, wherein the void volume (Vv) and material ratio are defined in accordance with ISO 25178-2:2012.
US11136432B2
The present invention relates to (i) a method of producing a conductive polymer, comprising polymerizing at least one of compounds (A1) represented by the formula (1) disclosed in the specification in the presence of a compound (B) having sulfo group; (ii) a method of producing a conductive polymer, comprising polymerizing at least one compound selected from a group consisting of at least one compound (A2) represented by the formula (2); and (iii) a method of producing a conductive polymer, comprising copolymerizing at least one compound (A1) and at least one compound selected from a group consisting of at least one compound (A2). The method of the present invention is a method for producing a one-liquid type conductive polymer in which it is possible to easily adjust the solvent affinity, the solubility, and other such aspects of performance according to the purpose.
US11136431B2
The disclosed technology relates to an article, such as a hose, tube, sheet, film, or filament made from a crystalline thermoplastic polyurethane composition, wherein the crystalline thermoplastic polyurethane composition comprises the reaction product of a polyisocyanate component, a polyester polyol component, optionally a chain extender component, and optionally a catalyst. The article is produced by melt or extrusion processes.
US11136429B2
A method of making a polymer having the structure (I): wherein L is a linking group, R is a hydrocarbon group or a substituted-hydrocarbon group, and x is 2 or more, preferably from 2 to 100, more preferably from 2 to 50; and wherein each {Q} is an identical polymer block or contains a plurality of polymer blocks. The method comprises reacting a di-halo initiator with a selected monomer one or more times and then reacting the resulting moiety with a dithiol compound of the structure HS—R—SH.
US11136423B2
To provide a modified polytetrafluoroethylene which is excellent in the moldability by paste extrusion and the mechanical property of the molded article. A modified polytetrafluoroethylene fine powder which is a fine powder of a non-melt-moldable modified polytetrafluoroethylene, characterized in that the modified polytetrafluoroethylene comprises units derived from tetrafluoroethylene, units derived from a perfluoroalkyl vinyl ether represented by CF2═CFO—CnF2n+1 (wherein n is an integer of from 1 to 6), and units derived from a perfluoroalkylethylene represented by CH2═CH—CmF2m+1 (wherein m is an integer of from 3 to 6), and that the content of the units derived from the perfluoroalkyl vinyl ether is from 0.1 to 0.25 mass % and the content of the units derived from a perfluoroalkylethylene is from 0.001 to 0.1 mass %, based on all monomer units in the modified polytetrafluoroethylene.
US11136421B2
Provided in the present invention is a solid catalyst component for use in olefin polymerisation, comprising Mg, Ti, a halogen, and at least one electron donor, the electron donor being a 2-substituted amino-phenyl ester compound selected from general formula (I). Also disclosed in the present invention are a catalyst comprising the solid catalyst component, and an application for the catalyst in olefin polymerisation, particularly in propylene polymerization. Also provided in the present invention is a high activity catalyst, said catalyst being able to obtain polypropylene of high isotacticity and wide molecular weight distribution, and not requiring an external electron donor to obtain high isotacticity polypropylene; during polymerization, Al/Ti and Al/Si are reduced, the polymerization time is lengthened, and high activity can still be maintained, suitable for producing low-ash polymers.
US11136420B2
Provided is a method of producing a water-absorbent resin comprising a step of polymerizing a water-soluble ethylenically unsaturated monomer in the presence of an internal-crosslinking agent, and a step of performing post-crosslinking, wherein: the step of polymerizing comprises one or more polymerization steps; all the polymerization steps are performed in the presence of both one or more azo based compounds and peroxides so that the both are coexistent in the all steps; in each polymerization step, a proportion of the azo compounds is 40-95 mass % relative to an amount of the azo compounds and the peroxides; the water-absorbent resin has a water-absorption capacity of physiological saline under a load of 4.14 kPa at 120 minutes passed from the start of water absorption of 20 ml/g or more; and the degree of swelling under a load at 30 minutes is 70%.
US11136419B2
A high pressure, free radical polymerization process to form an ethylene-based polymer, the process comprising at least the following step: polymerizing a reaction mixture comprising ethylene, using a polymerization system comprising the following: (A) a reactor configuration comprising at least one reactor that comprises at least two reaction zones, a first reaction zone (reaction zone 1) and an ith reaction zone (where i≥2); wherein the ith reaction zone is the last reaction zone, and wherein i is the total number of reaction zones; (B) at least two ethylene-based feed streams, a first ethylene-based feed stream and an nth ethylene-based feed stream, wherein the first ethylene-based feed stream is sent to the first reaction zone, and the nth ethylene-based feed stream is the last ethylene based feed stream sent to the reactor configuration; wherein n≤i; and RZn/RZ1 does not equal 1.0, where RZ1=mole fraction of make-up ethylene in the first ethylene-based feed stream to the first reaction zone; where RZn=mole fraction of make-up ethylene in the last ethylene-based feed stream sent to the reactor configuration; (C) a control system to control the percentage of the make-up ethylene in the first ethylene-based feed stream, and the percentage of the make-up ethylene in the nth ethylene-based feed stream; and wherein at least one reaction zone receives a CTA make-up feed stream comprising an alpha-olefin, and wherein the alpha-olefin has a chain transfer activity constant (Cs) value ≤0.10, and wherein the chain transfer activity constant (Cs) is measured at 1360 atm, 130° C.
US11136414B2
The present application discloses regioselectively substituted cellulose esters, films made from the regioselectively substituted cellulose esters and methods for making the same. The regioselectively substituted cellulose esters are synthesized using trifluoroacetic anhydride and cellulose with various acyl donors or acyl donor precursors.
US11136413B2
The present invention belongs to the field of tumor therapy and molecular immunology, and relates to a PDL-1 antibody, a pharmaceutical composition thereof and use thereof. In particular, the present invention relates to a PDL-1 monoclonal antibody or an antigen-binding fragment thereof, wherein the monoclonal antibody has a heavy chain variable region comprising CDRs as set forth in SEQ ID NOs: 15-17; and/or has a light chain variable region comprising CDRs as set forth in SEQ ID NOs: 18-20. The monoclonal antibody of the present invention can bind to PDL-1 specifically, and specifically remove immunosuppressive function of PDL-1 and activate T lymphocytes.
US11136412B2
Disclosed is an antibody which binds to a symmetrically dimethylated arginine analyte that can be used to detect a symmetrically dimethylated arginine analyte in a sample, such as in a homogeneous enzyme immunoassay method.
US11136397B2
The present invention relates to therapeutic combinations and methods for treating cancers using combination therapy.
US11136389B2
The disclosure provides compositions and methods for the treatment of ocular conditions associated with angiogenesis comprising administering an antibody that targets a tyrosine phosphatase inhibitor in a subject.
US11136382B2
The present invention provides an antibody or antibody fragment thereof for a targeted cytomembrane voltage-gated sodium channel α subunit Nav1.9. The specific binding target is a S3-4 ring of a voltage sensor paddle of a domain II of the voltage-gated sodium channel α subunit. The antibody or antibody fragment thereof is able to inactivate a voltage sensor valve, to make sodium ions unable to enter nerve cells normally, thereby achieving the effect of treating and relieving pains.
US11136377B2
In certain embodiments, this present invention provides antibodies and Fc fusion proteins with enhanced pharmacokinetics, such as biotinylated antibodies or biotinylated Fc fusion polypeptides.
US11136361B2
[Problem to be Solved] The object of the present invention is to develop a method of regulating a target RNA.
[Solution] There is provided a fusion protein comprising a functional domain which improves the protein expression level from mRNA and a PPR protein which can bind to a target mRNA in an RNA base-selective or RNA base sequence-specific manner.
US11136356B2
Immunogens comprising a recombinant HIV-1 Env ectodomain trimer stabilized in a prefusion closed conformation and methods of their use and production are disclosed. In several embodiments, the immunogen can be used to elicit an immune response to HIV-1 in a subject.
US11136352B2
The present invention relates to peptides, nucleic acids and cells for use in immunotherapeutic methods. In particular, the present invention relates to the immunotherapy of cancer. The present invention furthermore relates to tumor-associated cytotoxic T cell (CTL) peptide epitopes, alone or in combination with other tumor-associated peptides that serve as active pharmaceutical ingredients of vaccine compositions that stimulate anti-tumor immune responses. The present invention relates to 30 peptide sequences and their variants derived from HLA class I and class II molecules of human tumor cells that can be used in vaccine compositions for eliciting anti-tumor immune responses.
US11136348B2
Compounds of formula I are disclosed. The compounds are useful for promoting skeletal muscle hypertrophy or treating skeletal muscle atrophy.
US11136346B2
To provide a chiral reagent or a salt thereof.
The chiral reagent has following chemical formula (I). In the formula (I), G1 and G2 are independently a hydrogen atom, a nitro group (—NO2), a halogen atom, a cyano group (—CN), a group of formula (II) or (III), or both G1 and G2 taken together to form a group of formula (IV).
US11136344B2
A purification agent which includes a compound having a betaine structure, and which is for a sugar chain having a length equal to or longer than that of a monosaccharide or for a glycopeptide having a sugar chain having a length equal to or longer than that of a monosaccharide.
US11136339B2
Disclosed are a dihydroartemisinin dimer derivative, a pharmaceutical composition, and an application thereof. The derivative is an artemisinin dimer used for drugs treating or preventing malaria caused by plasmodium, drugs treating autoimmune diseases such as lupus erythematosus, and anti-tumour drugs, which is a pharmaceutical composition prepared from the dihydroartemisinin dimer derivative and a pharmaceutically acceptable carrier.
US11136338B2
The present invention relates to compounds of formulae I and H, or pharmaceutically acceptable salts or esters thereof. Further aspects of the invention relate to pharmaceutical compositions and therapeutic uses of said compounds in the treatment of diseases of uncontrolled cell growth, proliferation and/or survival, inappropriate cellular immune responses, inappropriate cellular inflammatory responses, or neurodegenerative disorders, preferably tauopathies, even more preferably. Alzheimer's disease.
US11136334B2
The present disclosure relates to solid forms of 3-(5-Fluorobenzofuran-3-yl)-4-(5-methyl-5H-[1,3]dioxolo[4,5-f]indol-7-yl)pyrrole-2,5-dione, processes for preparation thereof, pharmaceutical compositions thereof, and uses thereof in treating disease.
US11136325B2
The present invention relates to pyrrolopyrimidine compounds according to Formula I and their use in the prophylaxis and/or treatment of pain, inflammatory conditions, cardiovascular diseases, neurodegenerative diseases, neurological diseases, complications of type I diabetes, cancer and/or fibrotic diseases. In a particular aspect, the present compounds are ASK inhibitors, particularly ASK1 inhibitors. The present invention also provides methods for the production of a compound of the invention, pharmaceutical compositions comprising a compound of the invention, the use of the compounds in the prophylaxis and/or treatment of pain, inflammatory conditions, cardiovascular diseases, neurodegenerative diseases, neurological diseases, complications of type I diabetes, cancer and/or fibrotic diseases.
US11136324B2
An amide derivative inhibitor and a preparation method and an application thereof. Specifically relating to the compound shown in general formula (I), a preparation method for same, a pharmaceutical composition comprising said compound, and an application of same as an ASK inhibitor for the treatment of neurodegenerative disease, cardiovascular disease, inflammation, autoimmune and metabolic disease, each of the substituents in the general formula (I) being as defined in the description.
US11136323B2
Disclosed is a compound of Formula (I), or a stereoisomer thereof or a pharmaceutically acceptable salt thereof and pharmaceutical compositions comprising thereof. Also disclosed is a method of treating PI3Kδ related disorders or diseases by using the compound disclosed herein.
US11136318B2
The present disclosure relates to the preparation of methyl 2-(1H-indole-3-carbonyl)thiazole-4-carboxylate (ITE) and related compounds with high yield, purity, and scalability. The processes apply the use of a Weinreb amide intermediate as a scaffold for the preparation of ITE and structural analogs.
US11136312B2
The present disclosure describes novel compounds that are somatostatin receptor type 4 agonists.
US11136309B2
Provided are compounds having metalloenzyme modulating activity, and methods of treating diseases, disorders or symptoms thereof mediated by such metalloenzymes.
US11136304B2
The present disclosure relates to salts of (R)-1-(8-fluoroisochroman-1-yl)-N-methylmethanamine, crystalline forms thereof, and methods of preparation thereof, which are useful in the treatment of CNS disorders.
US11136296B2
The present application relates to novel substituted N-arylethyl-2-arylquinoline-4-carboxamide derivatives, to processes for preparation thereof, to the use thereof alone or in combinations for treatment and/or prevention of diseases, and to the use thereof for production of medicaments for treatment and/or prevention of diseases, especially for treatment and/or prevention of fibrotic and inflammatory disorders.
US11136290B2
Provided is a compound of Formula (I): wherein the variable groups are defined herein.
US11136286B2
[Problems to be solved] The present invention provides a novel diamine compound which allows for the synthesis of a polyimide compound having a high solubility in an organic solvent and a high melt moldability.
[Solution] The diamine compound according to the present invention is characterized by being represented by the following general formula (1): (wherein R1 to R8 are each independently selected from the group consisting of a hydrogen atom, a fluorine atom, a substituted or unsubstituted alkyl group, and a substituted or unsubstituted aromatic group; and at least one of R1 to R8 is a substituted or unsubstituted aromatic group).
US11136285B2
The present invention relates to a process for the continuous production of nitrobenzene by the nitration of benzene with nitric acid and sulphuric acid under adiabatic conditions, not the entire production plant being shut down during a production stop, but the production plant being entirely or at least partly operated in recirculation mode. The invention further relates to a plant for producing nitrobenzene and to a method for operating a plant for producing nitrobenzene.
US11136284B2
Provided is a hydrogenation method of a phthalate compound. According to the present invention, stereoselectivity of the hydrogenation reaction may be increased, and thus the content of a cis isomer in a product may be increased. As a result, quality of the hydrogenation product as a plasticizer may be improved.
US11136273B2
The present invention discloses liquid compositions that include an active compound, water, and means for inhibiting crystal formation or precipitation of the active compound in the liquid composition.
US11136272B2
The present disclosure is related to a method of producing a fired ceramic article. The method may include: heating a ceramic green body in a kiln, and controlling oxygen concentration in the kiln such that the oxygen concentration swings during the heating of the ceramic green body.
US11136270B2
A composite tile is comprised of coal dust and a pre-ceramic polymer that are mixed together and pyrolyzed to form a ceramic composite. For example, a chemical reaction during pyrolysis chemically converts at least a portion of the coal dust and pre-ceramic polymer to a fire proof ceramic composite suitable for use as a roofing tile either as pyrolyzed or as post-treated to seal cracks and pores formed during pyrolysis.
US11136266B2
The disclosure relates to embodiments of a thixotropic, non-cementitious, thermal grout and applications or methods of use of the grout related to horizontal directional drilling, trenchless technology, trenching, and installation of pipe, conduits, ducts, utility lines, and other product lines which may, e.g., be in trenches, underground, or under obstacles, such as a body of water or roadways.
US11136264B2
A chemically strengthened glass obtained by chemically strengthening a lithium-containing aluminosilicate glass, when representing a sheet thickness of the chemically strengthened glass by t (μm) and an internal stress at a depth×(μm) from a surface of the chemically strengthened glass by σ(x) (MPa), has a value of a ratio C=rE/rElimit being greater than or equal to 0.7 and less than 1.0 where rE (kJ/m2) is calculated from Expression (3) described above and rElimit=16×t/1000+3.
US11136260B2
The invention relates to a radiopaque glass having a refractive index nd of 1.480 to 1.561, this glass, apart from impurities at most, being free from SrO and PbO. The glass is based on the SiO2, Al2O3 and B2O3 system. The radiopacity can be adjusted using Cs2O in particular in combination with BaO and/or SnO2 optionally in conjunction with fluorine. The glass may be used in particular as dental glass or as optical glass.
US11136256B2
A sensor system to provide data for use to control manufacture of an optical fiber in microgravity including a diameter sensor to monitor a diameter of a fiber drawn from a preform material, a tension sensor to monitor tension of the fiber as the fiber is pulled from the preform material to a storage device and a controller in communication with at least one of the diameter sensor and the tension sensor to evaluate sensor data to determine at least one of a speed and rate at which the fiber is pulled from the preform material.
US11136253B1
The present disclosure provides a microbiological treatment system including a hydration system and microbiological degradation systems. The hydration system may include a gas-liquid mixing chamber, a gas inlet, a gas outlet, a liquid inlet, and a liquid outlet, the latter four being fluidly coupled to the chamber. The gas inlet is configured to introduce an ethylene oxide exhaust gas into the chamber to mix with an aqueous solution to form an ethylene oxide exhaust liquor. The liquid outlet is configured to discharge the ethylene oxide exhaust liquor. Each microbiological degradation system may include a degradation chamber containing degradation bacteria including one of anaerobic bacteria, facultative bacteria, or aerobic bacteria. The degradation chambers of the microbiological degradation systems may be in fluid communication sequentially in a predetermined degradation sequence, with the most upstream in the degradation sequence having a liquid inlet in fluid communication with the liquid outlet.
US11136251B2
The present disclosure provides compositions, methods, and devices for sensing, detecting, and/or selectively capturing phosphate from water. An exemplary method includes: contacting a ligand or a rare earth metal complex of a ligand as described herein with an aqueous phosphate-containing medium at a pH of 5 to 12 under conditions sufficient to bind phosphate (e.g., reversibly bind phosphate). In certain embodiments, the method further includes releasing the bound phosphate by contacting the bound phosphate complex with an aqueous medium at a pH of 0 to 4 under conditions sufficient to release the bound phosphate.
US11136250B2
The invention relates to a simplified modular reactor, where the method of purifying swimming pool waters can be carried out in an integral manner, where said method may comprise simultaneously applying the techniques of: oxidation-disinfection, ultraviolet radiation, and pH adjustment on the water to be treated.
US11136249B1
Provided herein are compositions and methods useful for the treatment of wastewater comprising colloidal impurities. In certain aspects and embodiments, the compositions and methods include a natural deep eutectic solvent (NADES) coagulant including a hydrogen bond acceptor and a hydrogen bond donor, wherein the NADES is a liquid at room temperature.
US11136245B2
Some embodiments include a method comprising: flowing a molten salt out of a molten salt reactor at a first temperature, heating the molten salt reactor to a second temperature above the melding point of the second salt mixture causing the second salt mixture to melt; flowing the second salt mixture out of the molten salt reactor; flowing a third salt mixture into the molten salt reactor; and cooling the molten salt reactor from the second temperature to a third temperature causing the third salt mixture to solidify on the interior surface of the housing. In some embodiments, the molten salt may include a first salt mixture comprising at least uranium. In some embodiments, the first temperature is a temperature above the melting point of the first salt mixture.
US11136237B2
A device for suppressing stray radiation includes a Micro-ElectroMechanical System (MEMS) sensor module and a conductive cage structure. The conductive cage structure may enclose the MEMS sensor module in order to suppress penetration of stray electromagnetic radiation with a stray wavelength λo into the conductive cage structure, and the conductive cage structure may be arranged to be thermally insulated from the MEMS sensor module. The device may also include a connecting line. The connecting line may be connected to the MEMS sensor module and fed through the conductive cage structure by a capacitive element.
US11136234B2
The present disclosure integrates an actuated tilting rehabilitation table, video tracking of the patient arm and opposite shoulder, a low-friction forearm support with grasping force sensing, remote data transmission and additional weighing means, one or more large displays, a computer and a plurality of simulation exercises, such as video games. The patient can be monitored by a local or remote clinician. The table tilts in order to increase exercise difficulty due to gravity loading on the patient's arm and shoulder. In one embodiment, the actuated tilting table tilts in four degrees of freedom.
US11136218B2
A method for fastening a rail of an elevator system to a bearing element fixed in an elevator shaft utilizes a clamp set having a clamp and a spacer. The clamp is arranged on a side part of a rail foot arranged on the bearing element whereby the clamp connects to the bearing element in a fastening zone of the clamp and a contact zone of the clamp is situated on a bearing side on an upper face of the side part. The spacer defines a mounting distance between the contact zone and the bearing side such that the clamp is partly elastically and plastically deformed in the fastening zone when connected. The spacer is then at least partially removed so that a distance between the contact zone and the bearing side is reduced.
US11136216B2
A portable hose winding machine includes a power head including a motor in a motor housing, with the motor having an output shaft and a bar coupled to the motor housing. The bar further includes an aperture or other fixtures such as a fairlead through which a hose is guided while being spooled up on a driven shaft.
Spooling is driven by a rod axially parallel to and radially spaced apart from a driven spool shaft, and a protective plate shields the user's hands from errant spinning hose end fixtures.
US11136207B2
A dust capture and reclamation system for a rubber conveyor belt having a housing for mounting over a portion of the rubber conveyor belt, a plurality of idler roller assemblies, a plurality of return roller assemblies, a trough for mounting under the rubber conveyor belt to catch granular material falling from the rubber conveyor belt, the trough having an inside surface, a mechanism for moving granular material along the inside surface to a collection point, a first access panel through one side for accessing an idler roller, and a second access panel through one of the pair of opposed side walls for accessing a return roller assembly.
US11136203B2
A material diverter for separating bulk goods includes a housing containing an inlet and at least two outlets, as well a guide element located between the inlet and the outlets that is pivotable about a pivot bearing in order to guide the material flow to one of the outlets. The material diverter further includes a pivot drive for pivoting the guide element, in order to align it between the inlet and one of the outlets. The housing includes a door that can be moved on the housing or removed therefrom. A first bearing element in the pivot bearing is located on the housing, and a second bearing element in the pivot bearing is located on the door. The guide element is received in the first and/or second bearing element such that it can be removed therefrom to facilitate servicing and cleaning of the material diverter and the guide element.
US11136199B2
The present invention relates a device (1) for producing batches (2) of products (3) from a plurality of products (3), said batches having a predefined configuration for palletizing in layers carried out downstream, said device comprising an upstream conveyor (4) which extends in a first conveying direction (6) and on which the products (3) are aligned in a row (5), a downstream receiving surface (7) intended to receive said batches, and a moving means (8) intended to transfer the products (3) brought by the upstream conveyor (4) to the downstream receiving surface (7). The moving means (8) comprises a main rail (9) and a plurality of shuttles (10) that are movable independently of one another and travel on said rail (9), each shuttle being intended to receive at least one product (3) on its upper surface. The present invention also relates an installation comprising this device and a corresponding method.
US11136186B2
Various embodiments of a trash can assembly (e.g., a receptacle configured to receive refuse, recycleable materials, or otherwise), and related methods, are provided. Some embodiments of the trash can assembly include a body component and a lid configured to move between an open position and a closed position. In some variants, the lid can be moved between the open and closed positions by a power operated driving mechanism, such as a motor and/or other drivetrain components. In certain embodiments, the trash can assembly includes a clutch mechanism to facilitate manual operation of the lid while inhibiting or preventing damage to the motor and/or other drivetrain components.
US11136185B2
This patent pertains to secondary containment systems. One implementation includes a support assembly that includes an elongate post member and a stabilization plate. In one instance, a stabilization plate is mounted on the elongate post member to reduce movement of the elongate post member when the stabilization plate is embedded in the ground. Another implementation includes a panel splice assembly including reinforcing members that secure overlapping, corrugated panels.
US11136184B2
A novel method for manufacturing a cubicle flexible intermediate bulk container is disclosed. At least two opposing sidewalls of the cubicle FIBC has a lower portion and an upper portion, both of which are formed of a combination of sheet material cut in rectangular and trapezoidal geometries.
US11136174B2
A container lid assembly includes a movable lid, a ratchet ring, a rotary symbol ring, an inner cover, and an annular housing. Once coupled to a container, the container lid assembly can automatically and accurately record the number of times for which it has been opened, thereby reminding the user of whether the contents of the container (e.g., medicine) have been used, lest the user miss a dose of the medicine or retake the medicine unnecessarily. The container lid assembly also allows a plurality of containers to be connected in series to facilitate carrying and management.
US11136162B2
A container formed from at least one blank of sheet material includes a tray, a cover configured to close the tray, and a locking device. The tray includes a tray front panel. The cover includes a cover front panel that extends downwardly from a front edge of a cover top panel. The cover front panel is configured to be positioned in an at-least partially overlapping arrangement with the tray front panel when the cover is closed. The locking device includes a locking tab hingedly attached to the cover top panel and struck in part from the cover top panel and in part from the cover front panel. The locking device also includes a locking recess struck from an upper edge of the tray front panel. The locking device is configured such that the locking tab can be pressed down into the locking recess to selectively secure the cover to the tray in a closed and locked configuration.
US11136160B2
The need for a bottom dispensing package comprising a base having an orifice comprising a slit-valve, which is less prone to leakage, even when a lower viscosity product is comprised in the container, is met by providing the container with a more elastic resiliently squeezable container.
US11136156B1
Aspects described herein include an apparatus for retaining a collapsible tote. The apparatus includes a wall member and one or more engagement members projecting from one or more surfaces of the wall member. The one or more engagement members are arranged and dimensioned to removably engage respective portions of the collapsible tote, suspending the collapsible tote beside a first surface of the one or more surfaces. The wall member is inclined such that, when the collapsible tote is suspended beside the first surface, the collapsible tote is gravitationally urged toward an uncollapsed configuration.
US11136142B2
A retractable runway edge sheave for use in an aircraft arresting system. The arresting system functions to extend a cable across a runway for capture by a tailhook of an aircraft. The retractable runway edge sheave is designed to raise and lower the cable. The disclosed system may also feature a ramping system.
US11136141B2
The disclosed embodiments relate to methods and systems for avoiding a collision between an aircraft on the ground and an obstacle using a three-dimensional visual indication of the area or plane of winglets on the wingtips of the aircraft. The method includes receiving a video image from a camera positioned in one of the winglets, the video image representing a field of view through which the winglet of the aircraft will pass along a present heading of the aircraft. Next a processor determines a three-dimensional area or plane within the field of view through which the winglet of the aircraft will pass. An overlay is displayed within the field of view to assist the pilot in avoiding collisions with obstacles.
US11136132B2
Composite airfoils of the present disclosure comprise a root section including a first surface. The airfoils comprise an intermediate section having a first surface and coupled with the root section at a first end. The airfoils comprise a tip section having a first surface and coupled at a first end with a second end of the intermediate section. The airfoils comprise a conductive material layer adjacent at least one of the first surface of the root section, the first surface of the intermediate section, and the first surface of the tip section. The conductive material comprises a first polymer, a second polymer, and a sulfonic acid.
US11136130B2
An environmental control system of an aircraft includes a ram air circuit including a ram air shell having at least one heat exchanger positioned therein, at least one dehumidification system arranged in fluid communication with the ram air circuit, a compressing device arranged in fluid communication with the ram air circuit and the dehumidification system, and an expansion device separate from the compressing device and arranged in fluid communication with the ram air circuit and the at least one dehumidification system. The environmental control system receives a flow of a first medium and a flow of a second medium. The environmental control system is operable in a plurality of modes and in a first mode, a flow of the first medium is provided to the compressing device and the expansion device in series.
US11136127B2
A supervision system for an aircraft for monitoring a safe charging of portable electrical devices of a passenger who may be in an attentive or an inattentive state, comprising a passenger seat, a power supply station assigned to the seat and used to supply electrical power to the portable electrical device, the portable electrical device being connected to the power supply station, a camera, which detects the state of the passenger situated on the seat, and an arrangement to distinguish whether the passenger is in an attentive or inattentive state. A method for safe charging of portable electrical devices is also presented and described, comprising the steps of detecting a passenger with a camera, analyzing whether the passenger is in an attentive state or in an inattentive state, and, if the passenger is in an attentive state, supplying a power supply station with electrical power to be provided to a portable electrical device connected to the power supply station.
US11136116B2
Embodiments are directed to a double Hooke's joint gimbal in a rotor system. An upper Hooke's joint has four arms extending radially outward to define first and second axes, and a lower Hooke's joint has four arms extending radially outward to define third and fourth axes. A pair of connectors couple the upper Hooke's joint and the lower Hooke's joint. A first set of bearings are positioned between arms on the upper and lower Hooke's joints and the connectors. The first set of bearings comprise an elastomer, such as elastomeric journal bearings. The upper Hooke's joint is coupled to a yoke and rotor blades by a driver assembly that allows rotor blade flapping. The lower Hooke's joint is coupled to and driven by a mast. A spherical bearing allows the upper Hooke's joint to move laterally along the mast.
US11136112B2
Aircraft landing gear forward trunnion support assemblies and related methods are described herein. An example aircraft wing disclosed herein includes a rear spar having a rear side and a front side opposite the rear side and a forward trunnion support assembly. The forward trunnion support assembly includes first and second vertical support fittings coupled to the rear side of the rear spar, and a trunnion housing with a bearing. The trunnion housing is coupled between the first and second vertical support fittings. The trunnion housing also includes first and second shoulders formed on a top side of the trunnion housing, each of the first and second shoulders having a respective open trough formed on a respective top surface thereof, thereby defining first and second cradles. A fuse pin is received within the troughs and has first and second ends extending through the first and second vertical support fittings respectively.
US11136107B2
An aircraft includes an aircraft body including a longitudinal axis and a wing box extending through the aircraft body. The aircraft also includes an attachment assembly coupled to the aircraft body and to the wing box. The attachment assembly includes a first attachment member coupled to the aircraft body and a second attachment member coupled to the wing box. The second attachment member is configured to couple to the first attachment member. The attachment assembly also includes a plurality of fasteners extending through the first attachment member and the second attachment member such that the plurality of fasteners are loaded in shear during a wing loading condition.
US11136099B2
An underwater scooter includes a scooter body, a duct, a motor, and a propeller. The scooter body includes a body part, a side part defining a first through hole, and a plurality of stopping members disposed on an inner wall of the first through hole. A gap is defined between every two adjacent stopping members. The duct includes a surrounding member defining a second through hole, a supporting member connected to an inner wall of the surrounding member, and a plurality of engaging members disposed on an outer wall of the surrounding member and spaced apart from each other. Each of the plurality of engaging members passes through a corresponding gap between two adjacent stopping members and abuts against two opposite sides of a corresponding one of the plurality of stopping members after rotating with respect to the corresponding one of the plurality of stopping members.
US11136095B2
Fender for protecting an object from damage comprising a core of at least a closed cell foam part, an intermediate layer fully enclosing the core comprising at least a fiber reinforced cloth, a coating that at least partly covers the intermediate layer. The invention also relates to a fixed or floating maritime structure provided with such a fender and to a method for manufacturing such a fender.
US11136094B2
A construction method for a column platform barrel deck and topside facilities, and a column platform. The construction method includes: prefabricating topside facilities in form of modules one by one, lifting each module to a predetermined position on the topmost deck of the upright barrel, and then connecting the modules to each other and forming a module-integration bottom deck at the bottom; during construction of the upright barrel, a skylight opening is reserved on the barrel topmost deck for the installation of the topsides, and the skylight opening allows the modular-integration bottom deck to be placed inside; an on-site closing gap is formed between the edge of the skylight opening and the outer edge of the modular-integration bottom deck perimeter; using the on-site closing gap connection structures to fill the on-site closing gap, so that the modular-integration bottom deck and the barrel topmost deck jointly form an integrated platform deck.
US11136087B2
An increase in the size of a leaning vehicle that has a double wishbone-type link mechanism is suppressed. A caliper is supported by a vehicle body frame. A disk includes: a disk contact part with which pads are allowed to be brought into contact; and a disk support part that, when the vehicle body frame is in an upright state, is supported by a support arm at a position that is further upward in an upward direction than an arm central shaft. When seen from a frontward direction, the disk support part supports the disk contact part so that an arm passing region through which a portion located between the arm central shaft in the support arm and a second end part of a left shock absorber and a second end part of a right shock absorber passes overlaps with the pads.
US11136085B2
A luggage rack for a motorcycle has a central body, a first wing element to one side of the central body, with a first fin extending at a right angle from the first wing element at an end of the first wing element, a second wing element to an opposite side of the central body, with a second fin extending at substantially a right angle from the second wing element at an end of the second wing element, a first and a second planar panel, spaced equally apart, parallel, and oriented vertically, extending downward and forward, each planar panel having a first notch facing forward at the forward extremity, and each planar panel having a second notch at a position rearward from the first notch, the second notch for each panel having a spring-loaded locking mechanism.
US11136083B2
A bicycle telescopic apparatus includes a first tube having a receiving space, a second tube telescopically received in the receiving space of the first tube, a position detector configured to detect a relative position between the first tube and the second tube in a longitudinal direction of the bicycle telescopic apparatus, and an output device configured to output a signal based on a detected result of the position detector. The signal can control a bicycle component other than the bicycle telescopic apparatus. A detecting point of the position detector is located in the receiving space of the first tube.
US11136081B2
A device for joining a lens to a housing of a lighting device of a motor vehicle, having a receptacle device for accommodating and securing the housing, a pre-centering device for aligning and clamping the lens on the housing during an alignment procedure, and having a holding device for accommodating the lens after the alignment procedure and for holding the lens during an adjustment process, wherein the holding device is releasably attached to the pre-centering device by fastening elements during the alignment operation, and wherein the pre-centering device, together with the accommodated lens and the holding device attached to the pre-centering device is movable relative to the receptacle device during the alignment procedure such that the lens and the holding device can be aligned on the housing accommodated in the receptacle device.
US11136073B2
A container including a first panel with a first edge having a first protrusion with a first contoured profile with at least one projection, a second panel with a second edge having a second protrusion with a second contoured profile with at least one projection, and a spline with a first channel that defines a recess with an interior profile, and a second channel separate from the first channel that defines a recess with an interior profile. The first and second channels receive the first and second protrusions, respectively, such that the first contoured profile is complementary to a portion of the interior profile and the second contoured profile is complementary to a portion of the interior profile. The first and second panel include a mid-section extending from the first and second edges, respectively. The first and second edges have a greater thickness than the thickness of the mid-sections.
US11136072B2
A cargo body panel includes an interior side, an exterior side, a primary recess, a secondary recess positioned within the primary recess, and a logistics track. The interior side defines an interior plane. The exterior side defines an exterior plane. The primary recess includes a primary recess interior side defining a primary recess interior plane and a primary recess exterior side defining a primary recess exterior plane. The primary recess interior plane is recessed from the interior plane in a direction toward the exterior plane. The secondary recess includes a secondary recess interior side defining a secondary recess interior plane and a secondary recess exterior side defining a secondary recess exterior plane. A distance between the secondary recess interior plane and the interior plane is greater than a distance between the primary recess interior plane and the interior plane. The secondary recess exterior plane is non-coplanar with the exterior plane.
US11136066B2
To improve bending rigidity of a side sill against an inward load during a lateral collision while suppressing a weight increase of the side sill, a vehicle side body structure includes a side sill that has a closed cross-sectional space extending in a vehicle longitudinal direction and a center pillar. A pillar inner provided in the center pillar has a pillar inner upper and a pillar inner lower. In a longitudinal direction of the side sill, an overlapping portion in which the pillar inner upper and the pillar inner lower overlap each other in side view in the closed cross-sectional space of the side sill is provided. The closed cross-sectional space further includes sections, each of which partitions the closed cross-sectional space in the longitudinal direction. These sections are joined to the overlapping portion and an inner surface, which faces the closed cross-sectional space, in the side sill.
US11136064B2
A rotation detection device includes a plurality of detectors each including a plurality of calculators respectively calculating a detection value. A control unit of the rotation detection device monitors abnormality of detection values respectively detected by the plurality of detectors, and, when determining abnormality, identifies a calculator calculating an abnormal detection value based on a result of comparison between the detection values of the plurality of calculators. Then, the control unit continues calculation of an absolute angle by using the detection values from the calculators other than the identified calculator.
US11136061B2
A vehicle of a steer-by-wire type includes a steering wheel and a turning device configured to turn a wheel. A control device for the vehicle is configured to: calculate a target turn angle being represented as a function of a steering angle of the steering wheel, and control the turning device such that a turn angle of the wheel becomes the target turn angle; receive driver-specified information indicating a specified maximum steering angle that is a maximum value of the steering angle specified by a driver of the vehicle; and flexibly set the function such that the target turn angle calculated according to the specified maximum steering angle is equal to a predetermined maximum turn angle.
US11136059B1
Embodiments described herein are for a position sensor system integrated into a steering column assembly of a vehicle. The position sensor includes an elongated target comprising a sloping top surface, a first arcuate lateral surface, a second arcuate lateral surface, and an attachment feature for connecting the elongated target to a moveable part of the steering column assembly. The position sensor also includes a sensor device comprising an attachment feature for connecting the sensor device to a stationary part of the steering column assembly and a sensor situated over the sloping top surface of the elongated target. The sensor is configured to detect a position of the elongated target relative to the sensor, where the position of the elongated target corresponds to a position of a steering column of the steering column assembly.
US11136058B2
A steering apparatus having inner and outer columns. The outer column includes a pair of side plate sections respectively extending in the axial direction, located on both sides in the width direction of the inner column, and has a column-side through hole that passes through in the width direction on one side of the inner column with respect to the height direction in a part in the axial direction thereof, and a column pressing section provided in at least one of the pair of plate sections and able to press the inner column in a direction away from the column-side through holes with respect to the height direction when displaced inward in the width direction, and a widening section in at least one of the pair of plate sections and pressed outward in the width direction via the inner column that is pressed by the column pressing sections.
US11136056B2
A planar carrier for mounting on a rim of a steering wheel without wrinkles, the planar carrier including a portion of planar flexible foil of roughly rectangular shape having two longitudinal sides and two lateral sides, wherein the length B of the lateral sides is 0.96 to 1.00 times the perimeter of the rim, and wherein N cut-outs per unit length are provided on each of the longitudinal sides. The cut-outs of one side are located in a staggered fashion relative to opposing cut-out portions on the opposite side. The optimum shape and size of the cut-outs may be determined as described. The planar carrier may be implemented as a heat carrier, a heating device and/or a sensing device.
US11136046B2
The present disclosure relates to a system and method of alarm for a vehicle. The present disclosure describes a alarm system for a vehicle for allowing a driver to practice a defensive drive in a weather environment which is hard to recognize the situation around the vehicle. An embodiment provides a alarm system for a vehicle including a camera operable to be disposed at the vehicle so as to have a field of view exterior of the vehicle, where the camera configured to capture image data, an image processor operable to process image data captured from the camera; a plurality of sensors disposed at the vehicle for sensing at least one of a front, side, or rear so as to capture sensing data, an alarm device for alerting a driver when detecting an object located in blind spot of the rear of the vehicle, and controller including at least one of processor configured to process at least one of (i) processing result of the captured image data and (ii) sensing data captured by the plurality of sensors.
US11136042B1
A method of assessing driver capability for operating an autonomous vehicle includes identifying, by one or more processors, a human operator of the vehicle, the human operator being associated with a driving capability profile. The method also includes determining human operator parameters associated with the human operator and determining an alertness level of the human operator based on the human operator parameters. The method further includes signaling, by a notification server of the vehicle, to the human operator with the signal, the signal requesting a response from the human operator. The method also includes updating, based on the response from the human operator to the signal, the driving capability profile to indicate a level of skill of the human operator at responding to the signal at the determined alertness level.
US11136040B2
A method of determining wheel slippage condition in a work vehicle includes moving the work vehicle from a first position to a second position, determining a drivetrain ground speed of the work vehicle using a drivetrain component, determining a predicted ground speed of the work vehicle using a sensor, detecting a wheel slippage condition by comparing the drivetrain ground speed to the predicted ground speed, and generating a driveline modification command to adjust propulsion power of the drivetrain component until the wheel slippage condition reaches a specified target. A method of adjusting acceleration for a work vehicle includes measuring a drivetrain acceleration, measuring an absolute acceleration, using the absolute acceleration to predict a ground speed, determining a steady state condition based on the commanded machine motion, the drivetrain speed, and the absolute acceleration, and modifying the predicted ground speed based on determination of the steady state condition.
US11136031B2
A method for controlling a trailer driven by an electric motor comprises defining a distance between the trailer and a towing vehicle as a neutral position and determining an actual distance between the trailer and the towing vehicle. A deviation between the actual distance and the neutral position is determined and output as a distance value. The braking of the trailer is electrically-actuated when the actual distance is decreased relative to the neutral position by at least a first distance value. The braking of the trailer is mechanically-actuated when the actual distance is decreased relative to the neutral position by at least a second distance value, wherein the second distance value is greater than the first distance value. The trailer is accelerated by the electric motor when the actual distance is increased relative to the neutral position by a third distance value.
US11136018B2
A speed planning device is disclosed. The speed planning device may perform a method including obtaining elevation information associated with a route for a vehicle; identifying a section of the route based on the elevation information, wherein the section is associated with a change in elevation; determining subsections of the section; determining respective slopes of the subsections and respective lengths of the subsections; obtaining information identifying a mass associated with the vehicle; generating a speed plan for the vehicle to traverse the section, wherein the speed plan indicates one or more speeds at which the vehicle is to correspondingly traverse the subsections based on the respective slopes of the subsections, the respective lengths of the subsections, and the mass associated with the vehicle; and providing the speed plan to permit the vehicle to be controlled to traverse the section according to the one or more speeds of the speed plan.
US11136011B2
Methods and systems are provided for mitigating reverse vehicle rollback. In one example, in response to a request to shift a transmission from reverse to forward when vehicle speed is elevated, vehicle brakes are applied and the actual transmission shift is delayed until the vehicle motion in the reverse direction is sufficiently decelerated. Additionally, the engine may be stalled and restarted before the transmission shift is performed.
US11136005B2
A vehicle wash system includes a vehicle treatment area and an overhead frame portion supporting a pair of side brushes. The side brushes are configured to treat the lateral sides of the vehicle and may also treat the front and back of the vehicle. The side brushes are configured to pivot between a vertical position, an outwardly angled position, and inwardly angled position. The side brushes may travel along the side of the vehicle in both the vertical and pivoted orientations. The side brushes may make multiple passes along the side of the vehicle, and the side brushes may change orientation during or between passes to treat different segments of the vehicle. The side brushes may be actively pivoted or may pivot in response to contacting the vehicle when shifted laterally into contact with the vehicle.
US11136002B2
A wiper blade is presented having a wiper strip, a primary frame, and a pair of secondary frames. The primary frame having a connection device capable of connecting the wiper blade to a wiper arm disposed on a top side of the primary frame, and a connection structure disposed, on opposite ends of the primary frame. The pair of secondary frame, each have a central pivot connection portion and two leg portions extending from the central pivot connection portion, a pivot structure disposed on the central pivot connection portion of the secondary frames wherein the pivot structure of the secondary frames are connected to the connection structures on the ends of the primary frame. A wiper blade is also presented having a wiper strip, a force distribution structure having opposite ends, and a cover.
US11136000B2
A system and method for providing access to a vehicle is provided. The system includes a plurality of capacitive sensors circumferentially spaced from one another in a circular arrangement defining a plurality of sensor nodes for receiving a touch input from a user in the form of a touch or a swipe. A controller unit is coupled to the plurality of capacitive sensors and a power source and is in communication with a plurality of vehicle systems and a latch mechanism. The controller unit detects a plurality of changes in capacitance of the plurality of capacitive sensors due to the touch input and determines whether the plurality of changes in capacitance matches a gesture sequence within a predetermined amount of time. The controller unit controls the latch mechanism in response to the communication with vehicle systems and changes in capacitance matching the gesture sequence within the predetermined amount of time.
US11135990B2
A method of using a support accessory rack includes aligning a first mounting portion of the support accessory rack with a first pin of a rollover protective structure. The method includes aligning a second mounting portion of the support accessory rack with a second pin of a second rollover protective structure. The method includes actuating the first pin to secure the first mounting portion to the rollover protective structure. The method further includes actuating the second pin to secure the second mounting portion to the rollover protective structure. The method includes pivoting a rotating support member of the support accessory rack away from the first mounting portion and the second mounting portion, and supporting the rotating support member onto a lateral bar of the rollover protective structure.
US11135988B2
A passenger restraint system for roller coasters, designed to maintain a passenger in an essentially upright posture, the passenger restraint system including a fixed column and a seat column designed to support and hold the passenger, which seat column is coupled to the fixed column so as to be movable relative to the fixed column and to be adjustable to the size of the passenger during an embarkation phase. The seat column is coupled to the fixed column by an articulated linkage, and the passenger restraint system further includes a device for balancing the seat column, which balancing device includes a cylinder fixed, at a first articulated end, to the fixed column and, at a second articulated end, to the seat column.
US11135984B2
A vehicle body rear structure includes: a cross member and a curvature portion each formed by a part of a floor panel, the part projecting downward at a rearward portion (spare tire pan) of the floor panel, wherein the cross member and the curvature portion each constitute a projected portion; and an underbody coating applied to the projected portions and having a first step and a second step which are oriented perpendicular to a front-rear direction.
US11135980B2
The invention relates to a folding interior lining panel of a motor vehicle comprising a first flap and a second flap which are articulated to one another along two articulation edges. The flaps have edge faces of similar thicknesses. The flaps being articulated to one another by two strips positioned some distance apart. Each of the strips has a middle part, a first end part pressed closely against the first edge face by a first plate and a second end part pressed firmly against the second edge face by a second plate. A second strip is positioned between the first strips, the second strip has a middle part, a first end part pressed firmly against the first edge face by a third plate and a second end part pressed firmly against the second edge face by a fourth plate.
US11135979B2
An emergency exit door assembly for a vehicle. The door assembly can include a door panel that is movably coupled to the wall of the vehicle. The door panel can have an inner surface and an outer surface. The door panel can be configured for selective movement between a closed position and an open position in which an opening within the wall is exposed. A headboard component can be incorporated into the door panel, and a bed pedestal within the vehicle can be positioned in proximity to the headboard component when the door panel is in a closed position.
US11135965B2
An optical axis control apparatus includes: an optical axis controlling unit for calculating, during stop of the vehicle, a pitch angle using an acceleration sensor provided in a vehicle and controlling, using the pitch angle, optical axis angles of headlights provided in the vehicle; and a rolling motion determination unit for determining, when the vehicle has started traveling, whether there has been a rolling motion during the stop of the vehicle. When the pitch angle has been changed during the stop of the vehicle and the rolling motion determination unit determines that the rolling motion exists, the optical axis controlling unit corrects, when the vehicle has started traveling and the rolling motion has been terminated, the amount change in pitch angle, using the amounts of correction set for each roll angle, and controls the optical axis angles using the corrected pitch angle.
US11135964B2
An apparatus for controlling an intelligent headlamp may include: a capturing unit configured to capture a forward image of a vehicle; a lamp driving unit configured to independently drive LEDs of a headlamp configured as a matrix LED; a storage unit configured to store an initial origin point, a changed origin point and an offset for adjusting the position of the headlamp; and a control unit configured to control the lamp driving unit to turn on the headlamp, detect an origin point from the forward image inputted from the capturing unit, set the offset for adjusting the position of the headlamp by comparing the detected origin point to the initial origin point or the changed origin point stored in the storage unit, and store a changed origin point, newly set based on the detected origin point, and the offset in the storage unit.
US11135958B2
A frame assembly for a vehicle seat includes a headrest frame including at least one support pole extending downwardly from the headrest frame and a seatback frame having a central body and a pair of outer brackets extending outwardly from the central body in spaced relationship to one another. A crossbar extends between and is rotatable relative to the pair of outer brackets. The at least one support pole is secured to the crossbar for facilitating concurrent rotation of the headrest frame with the crossbar. A locking mechanism is operably interconnected with the crossbar. An actuator is movable from a first actuator position to a second actuator position to engage the locking mechanism and move the locking mechanism from a locked condition to an unlocked condition. A slide shaft extends between the pair of outer brackets and supports the actuator during movement between the first and second actuator positions.
US11135952B2
A seat cover for a vehicle may include a lower or bench portion sized and configured to extend over a horizontally-oriented top of a bench of a vehicle seat. The lower portion may include a first section and a second section separated by a slit. The seat cover for the vehicle may also include an upper or backrest portion coupled to the lower portion. The upper portion may be sized and configured to extend upwardly over a backrest of the vehicle seat.
US11135942B2
A railway direct-current system according to the present invention is provided with: a feeding line that is connected to a plurality of electric power substations arranged along a railway; and a trolley line that is connected to the feeding line via feeding branch lines at an arbitrarily defined interval, wherein a superconductive feeding cable is connected to somewhere midway in each of railroad lines extending from the substations to the trolley line via the feeding lines, so as to be parallel with the railroad line.
US11135917B2
A head-up-display (HUD) device is disclosed and includes a plurality of light-emitting diodes (LEDs) configured to emit light beams in response to a control module of a vehicle generating a safety warning. The control module includes a processor that is configured to execute instructions stored in a nontransitory computer-readable memory. The HUD device also includes a first mirror that includes a transparent portion on a first side of the first mirror and a diffusive portion on a second side of the first mirror, and the light beams are configured to pass through the first mirror. The HUD device also comprises a second mirror that is configured to reflect the light beams toward a first reflective surface, and the second mirror is configured to reflect the light beams subsequent to the light beams passing through the first mirror.
US11135911B2
A heavy haul vehicle has a chassis capable of supporting a load to be transported by the vehicle. A first group of one or more first drive axles and a second group of one or more second drive axles are coupled to the chassis. The vehicle also has a first engine and a second engine. The first engine drives each axle in the first group of drive axles. The second engine drives each axle in the second group drive axles.
US11135910B2
An electric kart has a frame, a seat, four wheels, an electric motor operatively connected to two of the wheels, and at least one battery operatively connected to the electric motor. The at least one battery has a support structure mounted to the frame of the electric kart, and battery cells positioned on the support structure such that there is at least one air passage defined between the battery cells. Air passes through the at least one air passage when the electric kart is in motion to cool at least some of the battery cells. A battery for an electric kart is also disclosed.
US11135906B2
A side door assembly is provided for an automotive vehicle body having a side opening. The side door assembly includes a one-piece casting for hinged connection to the vehicle body. The casting forms a frame. At least one panel insert is selectively connected from the interior of the vehicle outward by a plurality of rotary attachment features to the frame. The frame includes a plurality of reinforcement features to add structure and rigidity, while reducing weight, to the side door assembly.
US11135905B2
A side door assembly is provided for an automotive vehicle body having a side opening. The side door assembly includes a front casting for hinged connection to the vehicle body. A rear casting is also provided for latch connection of the vehicle door assembly to the vehicle. An extrusion and/or extrusions connect the front and rear castings providing a side door assembly that is extremely light, enhancing the ability of the driver to enjoy the vehicle.
US11135898B2
A remote air conditioning start system includes a terminal of a user, a center server, and a vehicle that includes an air conditioner and is configured to communicate with the center server. The remote air conditioning start system includes first and second transmission units, first and second reception units, a start controller provided in the vehicle and configured to, when the second reception unit receives a start request, start the air conditioner, a determination unit provided in one of the terminal, the center server, and the vehicle and configured to determine necessity of defrosting of a window of the vehicle, and a notification unit provided in the terminal and configured to, when the determination unit determines that defrosting of the window is needed, notify the user that defrosting of the window is needed.
US11135897B2
An air duct system for passing an air flow emanating from an air outlet to a measurement device for detecting parameter measurement values for at least one parameter of the air flow, includes at least one collecting unit for collecting the air flow emanating from the air outlet. That one collecting unit can be disposed on the air outlet so that a contact surface of the collecting unit encloses at least one outlet opening of the air outlet circumferentially. The collecting unit includes a wall defining a continuous air duct with an inlet end section and an outlet end section. In order to improve the measurement of the parameter of the air flow, the air duct system includes at least one measurement chamber that is communicatively connected to a section of the air duct enclosed by the inlet end section, which, as a measurement chamber that is otherwise closed relative to the surroundings, either contains at least one pressure sensor or comprises at least one connection for communicatively connecting the measurement chamber to a pressure measurement device.
US11135892B2
An air conditioning system comprises a compressor, a rotary engine, and a condenser. The rotary engine comprises at least one drive shaft. The at least one drive shaft is operatively connected to the compressor and to the fuel tank. The condenser is operatively connected to the compressor. The evaporator is operatively connected to the condenser and to the compressor. The rotary engine combusts fuel to rotate the at least one drive shaft. Rotation of the at least one drive shaft operates the compressor to cause working fluid to flow such that the evaporator air conditions the passenger compartment.
US11135886B2
A vehicle includes a front wheel, a front wheel mounting portion, a vehicle body, and a roll mechanism. The wheels are disposed in a pair of the left and right and rotatable about the steering shaft as a rotation center. The portion is disposed in a pair of left and right, and the wheel rotatably mounted and includes a suspension. The body includes a seat on which an occupant sits. The mechanism connects the body and the portion. In the upright state, the roll axis of the mechanism is located at a position higher than the vehicle center of gravity when the occupant is not riding. When the body receives a centrifugal force at the time of turning, only the body among the body and the wheel rolls around the roll axis as the rotation center, whereby the body is inclined inward in the turning direction.
US11135875B2
A resin-metal composite member for a tire, the member including: a metal member; an adhesive layer; and a covering resin layer in this order, wherein: the adhesive layer includes a continuous phase containing a polyester-based thermoplastic elastomer having a polar functional group, and a discontinuous phase containing a styrene-based elastomer, and a ratio of the continuous phase with respect to an entirety of the adhesive layer is from 60% by mass to 93% by mass.
US11135869B1
The present invention relates to a recreation supplies container. The container comprises a body having a substantially triangular cross section defined by a first surface, a second surface, an inclined surface, a first flat surface adjoining operative top ends of the first surface and the inclined surface, and a second flat surface adjoining an operative bottom end of the inclined surface and a free end of the second surface; a first plurality of cavities is configured on the inclined surface, wherein the first plurality of cavities have a rectangular configuration; a second plurality of cavities is configured on the first flat surface, wherein the second plurality of cavities have a circular cross section; a working platform provided within the second flat surface, wherein the working platform is drawn out in an operational configuration thereof; a storage space defined by the surfaces of the body.
US11135866B2
A method of performing foil sleeking after printing for UV inkjet printer is disclosed, which comprises steps of: positioning a workpiece with printed patterns or words; then printing an undercoat layer on areas to be foil-sleeked of the patterns or words, then irradiate the undercoat by a UV lamp with a low irradiation intensity to allow the undercoat layer to form a viscosity; and finally sticking a foil on the undercoat layer.
US11135861B2
A printing apparatus provided with a detection circuit executes: printing a first undercoat color on a printing medium; performing a calibration with respect to the printed first undercoat color; printing an adjustment pattern using a first pattern color that has a complementary-color relationship with the first undercoat color; detecting the adjustment pattern using the detection circuit; and making an adjustment based on the detected adjustment pattern.
US11135858B2
A printer includes a medium supplier including a shaft support, to which a supply shaft of a roll medium is detachably attached, a medium temporary placement support located below the shaft support of the medium supplier and that receives and supports the roll medium prior to being attached to the medium supplier, and a conveyor that conveys a medium in a conveyance direction that is perpendicular or substantially perpendicular to an axial direction of the supply shaft, the medium being unwound from the supply shaft. The medium temporary placement support includes a support bar that extends in the axial direction, and a placement seat supported by the support bar. The placement seat includes a placement surface on which the roll medium is placed and that extends in the conveyance direction, and a curved portion that includes a convex curve in an upstream end portion of the placement surface in the conveyance direction.
US11135857B2
A system for a partially dried inkjet media conditioner can include a heated pressure roller to apply pressure to a first side of partially dried inkjet media and apply heat to a second side of the partially dried inkjet media.
US11135855B2
An image forming apparatus includes: a line head including multiple ink jet nozzles arrayed in a line direction; a storage device; and a controller circuit configured to determine an image width, the image width being a width of an image to be formed in the line direction, mandatorily eject ink from an ink jet nozzle group before forming the image, the ink jet nozzle group including multiple ink jet nozzles used to form the image having the image width out of the multiple ink jet nozzles, and store the image width in the storage device as a mandatory ejection width.
US11135853B1
The present invention relates to an ink circulation supply system for an inkjet head. The system is configured to supply ink to the inkjet head having a plurality of nozzles for ejecting the ink, and includes: a meniscus reservoir; a circulation reservoir; and an ante reservoir, the reservoirs where a first pressure connection pipe with a first pressure valve, a second pressure connection pipe with a second pressure valve, a first ink connection pipe, and a second ink connection pipe with an ink valve are provided, wherein when the internal pressure of the circulation reservoir is controlled to be lower than that of the meniscus reservoir, the ink stored in the meniscus reservoir is moved to the circulation reservoir without requiring use of a separate pump.
US11135841B2
A liquid discharge head includes a discharge port member including a discharge port, a flow path member including a pressure chamber and a liquid flow path, a substrate, and a structure that is arranged on the substrate on an upstream side of a center of the discharge port and that is configured to generate a flow of the liquid toward the discharge port. The liquid in the pressure chamber circulates. A position corresponding to a portion of the structure having a greatest height from a surface of the substrate is located on the upstream side of the center of the discharge port in a flow direction of the liquid. A thickness of the structure in a discharge direction of the liquid is 0.1 times or greater than a thickness of the liquid flow path in the discharge direction of the liquid.
US11135834B1
Certain examples describe a method of calibrating a printer and a printing system. An interferential pattern is printed in the form of a print calibration image on a print medium. Data representative of the interferential pattern as printed on the print medium is detected using an optical sensor. The printer is calibrated based on the captured data. The interferential pattern is based on a waveform that varies in amplitude along an axis perpendicular to a printing axis under calibration and has repeated sets of multiple patterns based on the waveform, the repeated sets having a varying pattern spacing in the printing axis under calibration.
US11135833B2
The invention relates to a method for verifying a printing plate, specifically a gravure cylinder, for errors in an engraving of the printing plate, comprising the following steps: Generating at least two proofs using a printing plate to be verified, capturing at least one digital image each of the at least two proofs with an image-capturing unit, comparing each of the digital images of the at least two proofs with the engraving template of the printing plate, wherein the comparison comprises the following steps: Detecting deviations between each of the images and the engraving template, and verifying that the detected deviations occur in identical fashion on the digital images of all of the at least two proofs, wherein a pseudo error is indicated if the comparison does not show identical deviations between the digital images of the at least two proofs, and wherein identical deviations indicate an engraving defect in the printing plate.
US11135830B2
The present invention relates to a filament suitable to be used in a 3D printing device, wherein the filament comprises a metal and/or ceramic powder, a thermoplastic binder and additives. The invention also relates to a process for producing a shaped body comprising the step of printing a shaped green body using the filament according to the invention. Also provided is the use of a filament according to the invention in a 3D printing device and a green body producible by mixing a metal and/or ceramic powder and a thermoplastic binder. The invention also relates to the use of a binder of the invention for the production of a filament for 3D printing devices.
US11135827B2
A nanofiber forest that includes a pattern or shape can be transferred to a substrate. The nanofiber forest can be configured to have any perimeter and/or internal shape or pattern using a stencil technique and/or using an engraving technique. This pattern can be transferred as a “negative image” of a corresponding pattern in a stencil or as a “positive image” by engraving the pattern directly into the nanofiber forest. For either type of pattern formation, the patterned nanofiber forest is transferred by applying a substrate to the pattern or to a nanofiber forest covered by a patterned stencil. Pressure is then applied causing the exposed surface of the nanofiber forest or pattern of nanofiber forest to adhere to the substrate.
US11135825B2
According to the present invention, a surface of a prepreg (104), said surface being provided with a partially fused structure (102A), and a surface of a metal member (110) are brought into contact with each other, and heat and pressure are subsequently applied thereto. After completely melting a resin containing a thermoplastic resin and adhering to the prepreg (104) so that a reinforcing fiber substrate (101) is impregnated with the molten resin, the resin is cured to obtain a matrix resin (105), thereby forming a CFRP layer (120) that serves as a fiber-reinforced resin material, and the CFRP layer is simultaneously compression-bonded to the metal member (110), so that a metal-CFRP composite body (100) in which the CFRP layer (120) and the metal member (110) are firmly bonded to each other is formed.
US11135823B2
The invention relates to novel processes for the lamination of semi-crystalline, high-melting point, low glass transition polymeric films, which are extruded and subsequently laminated on various thermally sensitive substrates to form laminated medical device constructs in a specific time interval to allow low processing temperatures to avoid polymer film and/or substrate degradation or heat-related distortions. Also disclosed are laminated medical device constructs made from such processes.
US11135820B2
Disclosed are compositions and methods for multilayer films, which, in one embodiment may include a core layer comprising a polyethylene stabilizer optionally in a masterbatch solution and at least 50 wt. % of high-density polyethylene. Further, the multilayer film may include a first skin layer comprising at least 90 wt. % ethylene-propylene polymer and antiblock, and a second skin layer consisting of an ethylene-propylene copolymer or terpolymer. Further still, the multilayer film may include a primer layer on the second skin, an aqueous barrier layer of ethylene vinyl alcohol polymer, polyvinyl alcohol polymer, or combinations thereof on the primer layer. And, further still, multilayer film may include a metallization layer on the aqueous barrier layer, wherein the multilayer film may be oriented in at least one direction.
US11135799B2
Disclosed is a fitment holder that includes a base, a hub extending from the base, and a fitment positioning structure comprising a plurality of pins. The plurality of pins may be configured to engage a wing of the fitment and the plurality of pins may include a plurality of heads residing in a plurality of countersunk areas formed in the base. The plurality of pins may also include a plurality of ends extending from a top surface of the base.
US11135794B2
A method for managing a carcass structure building line, a plant and a process for building tyre carcass structures, wherein the plant includes a carcass structure building line provided with a plurality of stations including an unloading station and n building stations. A group of forming drums being processed includes m forming drums being processed defining a first size of carcass structure being processed. Three groups of entering forming drums include respective entering forming drums, defining a second size of carcass structure being processed. A pair of support elements being processed includes a first and a second support element being processed and three pairs of entering support elements respectively include a first and a second entering support element. The invention also relates to a method for managing a carcass structure building line.
US11135792B2
The present application relates to a tire repairing system, comprising: an inflation device including an inflation housing and a motor; and a sealant container having a container housing, an air outlet of the inflation device can be connected to an air inlet of the sealant container, wherein the inflation housing is able to connect to the container housing in such a way that the container housing acts as a pedestal and the inflation housing is arranged on the container housing.
US11135781B2
Aspects of the disclosure relate to manufacturing a balloon envelope for use in a stratospheric balloon system. For instance, a stream of polyethylene mixture us extruded through an extruder in order to orient molecules of polymer chains of polyethylene and to provide an oriented film. The oriented film is passed through an electron beam and thereby crosslinking the polymer chains to provide a cross-linked film. The cross-linked film is heat sealed to form the balloon envelope.
US11135778B2
A method for optimizing a welding process to produce a weld joint having a predetermined strength includes measuring a plurality of melt layer thicknesses of weld joints for a plurality of sample assemblies formed by the welding process, measuring a plurality failure loads of weld joints for the plurality of sample assemblies, each of the measured plurality of failures loads being associated with one of the measured plurality of melt layer thicknesses, selecting a first failure load from the plurality of measured failure loads responsive to determining that the first failure load corresponds to a predetermined weld strength, and selecting a first melt layer thickness from the plurality of measured melt layer thicknesses that is associated with the selected first measured failure load.
US11135763B2
An assembly formed by additive manufacturing comprises a top face sheet, a bottom face sheet, and a core structure between the top face sheet and the bottom face sheet, the core structure comprising a plurality of cells, wherein structural elements of the core structure defining the plurality of cells exhibit at least one electrical property in at least one direction varying from at least one electrical property in a second, different direction and at least one structural property in at least one direction varying from at least one structural property in a second, different direction, wherein at least a portion of the structural elements comprises a radar absorbing structure, the structural elements comprising a matrix material and at least one additive dispersed in or on the matrix material. Related radar absorbing structures and related methods of fabricating the radar absorbing structures are also disclosed.
US11135759B2
A temperature adjustment part is configured to stretch a preform by moving a temperature adjustment rod toward a bottom surface portion (lower body portion) side of a body portion by a predetermined distance, after inserting the temperature adjustment rod into the preform to bring the temperature adjustment rod into contact with an inner surface of the body portion of the preform other than a boundary portion between the body portion and a neck portion.
US11135735B2
A precut module with one or more profiling heads and/or circular saws may be provided upstream of a saw module. The precut module may be used to implement a portion of a cut that would otherwise be made by the saw module, thereby reducing the depth of cut required at the saw module. In some embodiments, profiling heads may be used to profile a block that is wider than a desired side board. The block may be cut from the workpiece and sent to the edger. This may provide the same or better wood volume recovery and/or throughput speed than profiling the side board or cutting the side board from a flitch. In some embodiments, cut patterns for the precut module and other machine centers may be calculated and/or selected based on a desired depth of cut at the saw module, desired throughput speed, wood volume recovery, and/or other parameters.
US11135723B2
Systems and methods presented herein include a robotic wearable device testing system with a track drive system that includes one or more tracks having a plurality of attachment pads configured to attach to one or more wearable devices. Each track of the one or more tracks is configured to move along a path defined by the track. In addition, the robotic wearable device testing system includes a tap point drive system that includes one or more tap point sliders configured to slide laterally with respect to the track drive system. Each tap point slider of the one or more tap point sliders includes a tap point configured to wirelessly communicate with the one or more wearable devices when the one or more wearable devices are in close proximity with the tap point. Each tap point slider of the one or more tap point sliders also includes an electronic interference door configured to block wireless signals between the one or more wearable devices and the tap point. The robotic wearable device testing system also includes control circuitry configured to control relative movement of the one or more tracks and the one or more tap point sliders to position one or more wearable devices attached to respective attachment pads of the plurality of attachment pads in close proximity with a tap point of the one or more tap point sliders, and to control movement of the electronic interference door to allow or block the wireless signals between the one or more wearable devices and the tap point of the one or more tap point sliders.
US11135722B2
A simulation device for simulating the operations of a robot that follows a workpiece when the workpiece is conveyed by a conveyer that conveys workpieces along an arc-shaped track. The simulation device includes a robot model arranging section that arranges a robot model in virtual space; a conveyer model arranging section that arranges a conveyer model in the virtual space, the conveyer model being capable of conveying a workpiece model along an arc-shaped virtual track; a workpiece model arranging section that arranges a workpiece model on the conveyer model in the virtual space; a detection device model arranging section that arranges a detection device model in the virtual space capable of detecting the workpiece model; an operation range setting section that sets a following operation range of the robot model in the virtual space; and a simulation execution section that executes simulations.
US11135717B2
A detachable modular mobile autonomy module (MAM) for a modular autonomous bot apparatus includes a housing with latching points, an autonomous controller, location circuitry, external sensors monitoring an environment external to the MAM and providing sensor data to the controller, multi-element light panels on the housing driven by the controller; and a modular component power and data bus. The bus has a bottom side modular component electronics interface disposed on the housing that mates to a corresponding interface on another proximately-attached modular component of the bot. The MAM receives sensor data from the external sensors, receives outside sensor data from additional sensors disposed on a mobility unit of the bot, generates steering and propulsion control output signals based on location data from the location circuitry, external sensor data, mobility unit sensor data, and destination information data maintained by the controller, and generates transport and delivery information for the light panels.
US11135708B2
The present invention provides a screw feeding/fastening unit of a continuous screw fastening device which enables assuredly pulling screws out of a screw strip in tandem with a screw fastening operation even in case of using the screws each of which has, e.g., a flat shape below its head portion.
A screw feeding/fastening device of a continuous screw fastening device according to the present invention is a screw feeding/fastening unit 1 of a continuous screw fastening device which fastens screws 4, and it is configured to include a screw strip binding piece unbinding section 51 which supports a screw strip guide unit 2 to be rotatable in a direction orthogonal to a longitudinal direction of a bit by a shaft body 53 provided at a position before a feed case 22 in a feeder unit 21 and to be restorable to its original position by a spring 54, has on the screw strip guide unit a turning receiver 6 which abuts on a part of a slide frame and receives turning force at the time of a slide operation of the slide frame 31 toward the screw strip guide unit, and turns the screw strip guide unit together with the turning receiver around the shaft body as a spindle in a direction along which a tip side gets away from a screw at the fastening acting position to impart unbinding force to a screw strip binding piece 3a at the time of fastening the screw.
US11135699B2
Systems and methods of providing run-time quality control and monitoring of a single or multiple sequencing runs are provided herein. In some embodiments, the run-time system includes or is in communication with a processor capable of determining various types of run-time information relating to the quality, progress, etc. of various sequencing runs. In some embodiments, the system can also be in communication with a user interface, for example, a GUI, capable of representing and communicating various types of information to a user regarding the quality of the individual or multiple runs, the functioning of the instrument, an error event, etc. Additionally, the system can capable of receiving actionable information from a user via the GUI thereby allowing the user to terminate or repeat various sequencing steps in a particular run, terminate a entire run, terminate all runs, allow a run to proceed, etc.
US11135698B2
Disclosed is a processing apparatus that includes a chamber accommodating a workpiece, a nozzle provided within the chamber, a measuring unit measuring the supply flow rate of the processing fluid supplied to the nozzle, an opening/closing unit performing opening/closing of the flow path of the processing fluid, and a controller. The controller sends an opening/closing operation signal that causes the opening/closing unit to perform an opening/closing operation according to recipe information that indicates processing contents. After sending the opening/closing operation signal to the opening/closing unit according to the recipe information, the controller starts the integration of the supply flow rate based on the measurement result of the measuring unit, monitors the rise of the supply flow rate based on the calculated integrated amount, and when supplying a specific flow rate, monitors the supply flow rate based on a value actually measured by the measuring unit.
US11135695B2
A rotary table device according to the present invention includes: a spindle that supports a table; a driving mechanism that drives the spindle; a load detection portion that detects a load of the driving mechanism; a clamp mechanism that inhibits rotation of the spindle; a rotation control portion that causes the driving mechanism to drive the spindle with a predetermined inspection pattern after the clamp mechanism starts releasing clamping; and a determination portion that determines whether good or not with respect to an operation of the clamp mechanism based on of change over time in the load detected by the load detection portion when the spindle is driven with the inspection pattern.
US11135693B2
This machine tool system is provided with a tool holder adaptor that has a flange having formed therein: a hole part that contains a tool holder; and an engagement part that engages with a hand of a self-propelled robot, wherein when transporting the tool holder to a machine tool from a tool storage that contains a plurality of tool holder adaptors, the self-propelled robot grasps the tool holder adaptor to transport the tool.
US11135689B2
There is provided a tool blade, comprising a backing strip particles of abrasive material and a binder layer of binding material which binds the abrasive particles along an edge of the backing strip, wherein the edge of the backing strip is pre-formed with teeth, on which the abrasive particles are bound by the binding material. A profiled cutting portion extends beyond the pre-formed teeth. The pre-formed teeth are shaped as generally triangular waves or are flattened at least partially along an upper edge on which the cutting portion is at least partially disposed. A method of making such a blade is also provided.
US11135688B2
A method for producing a microchannel bundle heat exchanger (1) includes providing a multiplicity of tubular microchannels (2); incorporating the microchannels (2) in a weaving device; interweaving the tubular microchannels (2) with a plurality of warp wires (3) in the weaving device, and generating at least one heat exchanger mat (4) from the tubular microchannels (2) which are connected to one another by means of the warp wires (3); shaping at least one heat exchanger pack (8) from the at least one heat exchanger mat (4), in particular by folding and/or rolling up the heat exchanger mat (4); and adhesively bonding the tubular microchannels (2) at two mutually opposite end sides (9, 10) of the heat exchanger pack (8).
US11135686B2
A method is for positioning a hollow workpiece obtained by casting and that enables the workpiece obtained in this way to be machined in accurate manner. The workpiece is obtained by a casting method involving a mold and a sacrificial core inserted inside the mold and serving to form at least one cavity in the workpiece. The workpiece includes surfaces of a first type defined during casting by the surfaces of the mold, and surfaces of a second type defined during casting by the surfaces of the core. A frame of reference for positioning the workpiece is constructed that includes at least three reference points (P1-P3) belonging to surfaces of the second type of the workpiece.
US11135680B2
Methods and computer-readable media for producing at least one portion of a layer of a three-dimensional component by irradiating at least one powder layer by at least one high-energy beam, e.g., a laser beam are disclosed. The methods include irradiating the powder layer by the at least one high-energy beam in a processing field, wherein the at least one high-energy beam is moved in a continuous oscillating movement over the powder layer in a first direction to produce a line-shaped irradiation region in which the powder layer is melted, and wherein the line-shaped irradiation region is moved over the powder layer in a second direction that differs from the first to produce the portion of the layer of the three-dimensional component.
US11135670B2
A submerged arc welding apparatus includes a first wire feeder feeding a first hot wire towards a work piece; a first contact tube transferring current to the first hot wire for arc generation to create a weld puddle; a second wire feeder feeding a cold wire at a variable feed speed towards the weld puddle; one or more sensors configured to continuously measure, during a welding phase, at least a first active welding parameter related to at least the first hot wire; and a control unit. The control unit is configured to determine different target values for the variable feed speed of the cold wire based on different values of the at least a first active welding parameter such that a different target value for the variable feed speed of the cold wire is determined according to a different value of the at least a first active welding parameter.
US11135665B2
A handheld power tool (100) comprising at least one orientation sensor (150) is provided. The handheld power tool (100) is operatively connected to a controller (160; 210) and said controller (160; 210) is configured to receive orientation data from the at least one orientation sensor (150), wherein the orientation data comprises information associated with an orientation of at least a portion of the handheld power tool (100) and to determine operational data based on the orientation data, said operational data representing work performed using the handheld power tool (100). The operational data is determined by determining the orientation of the power tool based on the received orientation data from the at least one orientation sensor (150).
US11135660B2
A cutting processing system includes: a spindle mounted with a cutting tool in which a lubrication discharge path is formed along the central axis thereof for rotating the cutting tool; a lance provided inside the spindle in order to supply oil and air to the cutting tool; and a rotary union mounted on the end portion of the spindle for supplying the oil and the air to the lance in a non-mixed state.
US11135658B1
A first section for connecting a tool holder to the machining center and a tool holding section for receiving and holding a shank of a tool therein. A cavity is provided at the bottom of the retaining bore opposite from the front face of the tool holding section with a diameter larger than a diameter of the retaining bore near the front face of the tool holding section for disrupting induction of heating of the first section reducing the time to heat the tool holding section.
US11135646B2
A plate, a plate-holding apparatus, and a holding method for the plate for facilitating work to attach the plate to a plate-receiving metal frame of a sliding nozzle device. A gap is ensured between a to-be-held portion of the plate and an inner wall surface of an engagement groove such that, when the plate is held by engaging the to-be-held portion of the plate with the engagement groove of a holding portion of the plate-holding apparatus, the plate is movable in the longitudinal direction, the width direction, and the thickness direction of the plate.
US11135640B2
The present invention relates to a press-type composite internally and externally threaded portion forming system. In this case, the press-type composite internally and externally threaded portion forming system includes an expansion-type collet core unit (10) and a contraction-type collet core unit (20) as its principal components so that internally and externally threaded portions are formed by means of a press method in a composite manner in such a way that the expansion forming force of the expansion-type collet core unit (10) and the contraction forming force of the contraction-type collet core unit (20) simultaneously act on the inner and outer circumferential surfaces of a workpiece in opposite directions.
US11135639B2
A device for guiding and directing a metal sheet in a bending machine to form continuously a conical structure, in particular a frustoconical structure, comprises: resting and contrasting arrangement extending along a closed path, and suitable for restingly receiving a longitudinal edge of the metal sheet and contrasting a movement of the edge in a direction that is transverse to a preset advancement trajectory of the metal sheet; a supporting body for the resting and contrasting arrangement, having at least one oblong lateral portion that is suitable for facing the edge and configured for conforming the resting and contrasting arrangement to the longitudinal profile of the edge so as to obtain an extended zone of contact with said edge and impose resting and contrasting pressure distributed along the edge; the resting and contrasting arrangement is movable around the supporting body along the closed path to accompany the edge of the metal sheet by a distributed contact devoid of relative sliding and rolling, so as to impose on the metal sheet the advancement along the desired advancement trajectory to and through the bending machine. The corresponding method is also provided.
US11135635B2
Disclosed is a process for the blanking of metal parts, in which a multi-layered basic material with a number of mutually stacked, preferably essentially identical, individual layers is placed and clamped partly between a blanking die and a blank holder and partly between a blanking punch and a counter punch and wherein the blanking punch and the counter punch that are moved relative to the blanking die and the blank holder over a distance corresponding to at least a thickness of the multi-layered basic material whereby several blanked parts are cut and separated from the multi-layered basic material.
US11135634B2
To reduce warping of vertical wall portions without causing buckling occurring in a component shape not having a flange portion. A punch and a pad sandwiching a top sheet portion therebetween in the sheet thickness direction, bending blades for bend-forming the vertical wall portions, and stoppers facing the bending blades in the press direction and constraining end portions of a material to be machined are provided. The punch is supported by a first cushion component elastically expandable and contractible in the press direction. The bending blades each have an upper die component and a lower die component disposed facing each other in the press direction with an interval (D) equal to or larger than a set compression amount and a second cushion component interposed between the upper die component and the lower die component, maintaining the interval (D), and contractible in the press direction at a predetermined pressure or more. The cushion pressure of the second cushion component is lower than the cushion pressure of the first cushion component and has such cushion pressure that the second cushion component does not contract during the bend-forming of the vertical wall portions.
US11135633B2
A method or apparatus to produce an L-shaped pressed component includes, where a portion of a blank, having tensile strength of 1180 MPa or more, is held in a state of being clamped by a blank holder and a die, and a portion of the blank, to be formed into a top plate is held in a state of being clamped by a pad and a punch; the second step where a vertical wall, a concave ridge and a flange on the inner side of a curved portion are formed by, bend forming with a bending die, forming one, two or more material inflow promoting portion; and the third step where the die is moved in a direction toward a side where the blank holder is disposed to form a vertical wall, a concave ridge, and a flange on the outer side of the curved portion by draw forming.
US11135631B2
In a cooling path, hot rolled material composed of metal is cooled. The cooling path has a pump which extracts coolant from a coolant reservoir and feeds said coolant via a line system to a number of coolant outlets which are controlled by means of valves positioned upstream of the coolant outlets. A control device of the cooling path determines activation states (Ci) for the valves for a respective point in time taking into consideration coolant flows (Wi) which are intended to be discharged via the coolant outlets at the respective point in time, in conjunction with a working pressure (pA) of the coolant prevailing at the inlet side of the valve. By adding the coolant flows (Wi), said control device determines a total coolant flow (WG).
US11135629B2
A hazardous material storage repository includes a drillhole extending into the Earth and including an entry. The drillhole includes a vertical drillhole portion, a transition drillhole portion coupled to the vertical drillhole portion, and a hazardous material storage drillhole portion coupled to the transition drillhole portion. The hazardous material storage drillhole portion is located below a self-healing geological formation and is vertically isolated, by the self-healing geological formation, from a zone that comprises mobile water. The repository includes a storage canister positioned in the hazardous material storage drillhole portion and sized to fit from the drillhole entry through the vertical drillhole portion, the transition drillhole portion, and into the hazardous material storage drillhole portion. The storage canister includes an inner cavity sized to enclose hazardous material.
US11135626B2
A substrate dry cleaning apparatus, a substrate dry cleaning system, and a method of cleaning a substrate are disclosed. The substrate dry cleaning system includes a substrate support and a reactive species generator. The reactive species generator includes a first conduit defining a first flow channel that extends to an outlet of the first conduit, the outlet of the first conduit facing the substrate support, a first electrode, a second electrode facing the first electrode, the first flow channel disposed between the first electrode and the second electrode, a first inert wall disposed between the first electrode and the first flow channel, and a second inert wall disposed between the second electrode and the first flow channel.
US11135625B2
The invention provides an anti-fouling lighting system (1) configured for preventing or reducing biofouling on a fouling element (1201) of an object (1200). The fouling element (1201) is during use at least partly moving and at least temporarily exposed to water. Fouling is prevented by irradiating an anti-fouling light (211) onto said fouling element (1201). The anti-fouling lighting (1) system comprises at least one laser light source (2) configured to generate the anti-fouling light (211) and to provide said anti-fouling light (211) to said fouling element (1201) during use, wherein the system (1) is arranged such that during use the fouling element (1201) at least partly moves with respect to the laser light source (2).
US11135623B2
A wafer transport container interior atmosphere measurement device is arranged in wafer transport container. The device detects an atmosphere in the wafer transport container and communicates the atmosphere. The device includes a detector, a transmitter, and a power source. The detector detects the atmosphere in the wafer transport container. The transmitter wirelessly transmits a first information including a detection result by the detector to an external receiver. The power source supplies electric power to the detector and the transmitter.
US11135613B2
A metering valve has a closing member and a valve seat. The closing member is movable between a closed position on the valve seat sealing a material outlet, and an open position raised above the valve seat leaving the outlet clear. An actuating element rigidly connected to the closing member is arranged between first and second piezo-actuators at a distance from the first piezo-actuator in the closed position less than the maximum length change of the first piezo-actuator, or lies loosely thereon and at a distance from the second piezo-actuator longer than the maximum length change of the first piezo-actuator. The actuating element in the open position is arranged at a distance from the second piezo-actuator less than the maximum length change of the second piezo-actuator, or lies loosely thereon and at a distance from the first piezo-actuator greater than the maximum length change of the second piezo-actuator.
US11135612B2
Rotating applicators are disclosed. A disclosed example apparatus includes an inlet to receive a surface coating to be applied to a surface of a workpiece, a shaft having a fluid channel extending therethrough, where the fluid channel is in fluid communication with the inlet, and an applicator coupled to an end of the shaft, where the applicator has an opening in fluid communication with the fluid channel. The apparatus also includes a pump to cause the surface coating to flow from the inlet to the opening, and a motor to rotate the shaft while the applicator dispenses the surface coating from the opening.
US11135611B2
The present invention provides an automated system for spraying an wall of a building. The automated system comprises a carrier; a robotic mechanism mounted on the carrier, the robotic mechanism further having an end effector adapted to support a spray nozzle thereon; a visual monitoring system configured to scan structural characteristics and profiles of the wall; a computing device disposed in communication with the visual monitoring system and the robotic mechanism, wherein the computing device is configured to receive the scanned structural characteristics and profile of the wall from the visual monitoring system; and a controller communicably coupled to the computing device, the controller configured to independently control operation of respective ones of the robotic mechanism, and the spray nozzle according to the scanned structural characteristics and profiles of the wall.
US11135608B2
A dispensing device for paste products, including toothpaste, is provided. The dispensing device includes a container, a pumping diaphragm and a head applied to the container. The head is equipped with a tube and a button for acting on the diaphragm and deforming it for dispensing. The button has a pressure surface for a user's dispensing action. An extension element which, in an active position, is arranged as an extension of the pressure surface of the button, increases a leverage effect.
US11135603B2
There is provided a method of forming a hydrocyclone body including assembling sintered alumina blocks (27) against a form (37), holding the blocks (27) in place with tape (40), locating a hydrocyclone housing over the blocks (27), filling a space between them with settable epoxy/ceramic composite to secure the blocks (27) to the casing, and removing the form (37), resulting in a substantially continuous, wear resistant surface.
US11135599B2
A centrifugal separator recovers high specific gravity solids such as whole cells while at the same time enabling sedimentation of low specific gravity solids such as cell debris. The separator is provided with a dual zone separator liner with concentric separator shells or zones. Feed fluid is introduced into an inner shell. High specific gravity solids accumulate against the inner wall of the inner shell. Feed fluid flows into the coaxial outer shell where lower specific gravity solids accumulate on the inner wall of the outer shell under higher g-force relative to that within the inner shell for the same rotational speed. Feed fluid flows out an exit channel. Longitudinal, planar vanes are radially disposed between an outer shell inner wall and an inner shell outer wall. After centrifugation, feed fluid in the inner shell is drained, then accumulated solids are drained from the inner shell into an appropriate receptacle.
US11135594B2
Assay cartridges are described that have a plurality of chambers and a fluidic network that includes fluidic conduits and a multi-port valve designed to selectively connect the valve inlet and one valve outlet through a fluidic connector in the valve as the remaining valve outlets are sealed.
US11135589B2
Large bioreactors based on microfluidic technology, and methods of manufacturing the same, are provided, The big microbioreactor can include a chip or substrate having the microfluidic channels thereon, and the chip can be manufactured by forming a master mold, forming a male mold from a photopolymer plate using replica molding with the Fmold, and transferring features of the male to a polymer material.
US11135577B2
The invention provides: an exhaust-gas-purifying metal substrate capable of achieving both low pressure loss and high purification performance; and an exhaust gas purification device using the metal substrate. The invention relates to an exhaust-gas-purifying perforated metal substrate in which a corrugated foil and a flat foil are layered and made into a cylindrical shape, wherein: the perforated metal substrate includes from 50/in2 to 800/in2 of cells; the corrugated foil includes a plurality of first holes having an area that is from 2.0 to 50 times the average opening area of the cells; the flat foil includes a plurality of second holes having an area that is from 3.0 to 100 times the average opening area of the cells; and the average value of the area of the first holes in the corrugated foil is smaller than the average value of the area of the second holes in the flat foil.
US11135574B2
The present invention relates to a catalyst system comprising: i. a first layer of a hydrocarbon conversion catalyst, the hydrocarbon conversion catalyst comprising: a first composition comprising a platinum group metal on a solid support; and a second composition comprising a transition metal on an inorganic support; ii. a second layer comprising a cracking catalyst; and to a process for conversion of a hydrocarbon feed utilizing this catalyst system.
US11135573B2
An oligomerization catalyst, oligomer products, methods for making and using same. The catalyst can include a supported nickel phosphate compound. The catalyst is stable at oligomerization temperatures of 500° C. or higher and particularly useful for making oligomer products containing C4 to C26 olefins having a boiling point in the range of 170° C. to 360° C.
US11135568B1
The present disclosure relates to methods and systems for regenerating molecular sieves used in an alcohol dehydration process after the molecular sieves have become saturated with water.
US11135564B2
The present invention discloses novel porous polymeric compositions comprising random copolymers of amides, imides, ureas, and carbamic-anhydrides, useful for the synthesis of monolithic bimodal microporous/macroporous carbon aerogels. It also discloses methods for producing said microporous/macroporous carbon aerogels by the reaction of a polyisocyanate compound and a polycarboxylic acid compound, followed by pyrolytic carbonization, and by reactive etching with CO2 at elevated temperatures. Also disclosed are methods for using the microporous/macroporous carbon aerogels in the selective capture and sequestration of carbon dioxide.
US11135557B2
An apparatus, system and method to capture water power from head or pressure is provided utilizing pipes, inlets, and outlets. The apparatus comprises a central bore having an internal diameter suitable for a fluid flow, the fluid flow moves inside the central bore through the apparatus, and at least one outlet, the fluid flow exits the apparatus through the at least one outlet, optionally, a plurality of inlets for flowing additional fluid to the central bore mix the fluid flow with the additional fluid from the plurality of inlets. The apparatus can further mix the fluid through additional mixing devices and additional devices can be used to recapture energy such as hydroelectric power from the fluid flow. The system and method can capture water energy from the fluid flow.
US11135548B2
A heat exchange flow path portion is formed by alternately winding two spirally-shaped first and second heat transfer walls, with a predetermined gap interposed therebetween in the radial direction of the flow path pipe, around the outer periphery of a cylindrical flow path pipe, in which a cooling heat source is disposed in a main heat transfer flow path inside thereof. An inlet flow path and an outlet flow path for introducing compressed air into the flow path pipe and discharging compressed air from the flow path pipe are alternately formed, in the radial direction, from the gap between the heat transfer walls. Heat exchange is performed between compressed air that flows in the flow path and compressed air that flows in the flow path.
US11135547B1
An air-cooled condensing heat exchanger system (“ACHX”) installed in a fossil power plant flue gas treatment system recovers water and low temperature waste heat from boiler flue gas for advanced coal fired power plant applications. More particularly, the ACHX system recovers water from combustion flue gas by phase change. To recover water from flue gas, the ACHX system uses ambient air from an air intake installed on the stack to cool down the flue gas in the ACHX.
US11135542B2
This present disclosure relates to processes and apparatuses for removing contaminants from hydrogen streams. More specifically, the present disclosure relates to processes and apparatuses wherein hydrogen is used in units that utilize catalysts that are sensitive to oxygenates. The contaminants like carbon oxides and water are removed simultaneously from the hydrogen stream to provide a rich hydrogen stream with high purity to units that utilizes catalysts that are sensitive to oxygenates.
US11135540B2
A dust collecting device includes a cylindrical filter, a backwash auxiliary member that is disposed at an end portion of the filter and of which at least a part is disposed in a cylinder of the filter, and an air current generation unit that generates a backwash air current that passes through the backwash auxiliary member and flows into the cylinder of the filter, in which the backwash auxiliary member includes a rectification unit that extends spirally in an axial direction of a center axis of the filter.
US11135536B2
The present disclosure provides a purification device comprising: a main body, and a water-outlet module, wherein the module includes a fixed cover fixed to the main body so as to protrude forward of the main body, a vertically-movable cover moving vertically while bearing against the fixed cover, and a water-outlet nozzle mounted on a bottom of the vertically-movable cover, wherein a stopping protrusion protrudes outward from a bottom lateral face of the vertically-movable cover.
US11135534B2
A modular support structure comprising multiple chord or arc modules configured to selectively fixedly engage adjacent modules to define a completed annular support structure configured to support a rotary element of a rotary filter. The modular chord or arc segments may fixedly engaged an adjacent chord or arc segment through a fixing mechanism selected from the group consisting of: fasteners, clamps, pins, bolts, locks, locking mechanisms, key and socket mechanisms, spot welding, welding, adhesives, and other fastening mechanisms configured to engage and disengage adjacent chord or arc modules with ease.
US11135531B2
A filter device with a removable termination part (81; 82) and a housing (3) that receives a replaceable filter element (5) having two end caps (25,47). Between the end caps, a filter material (12) extends. A positioning device (65) is arranged between the termination part (81; 82) and one end cap (47). The positioning device positions the filter element (5) within the housing (3), at least when viewed in the circumferential direction of the filter element, in interaction with at least one corresponding positioning element (71) of the end cap (47).
US11135524B2
An excavator shovel assembly has an excavator shovel and a shovel arm. A shovel swivel locking device locks the excavator shovel relative to the shovel arm. It has a shovel connecting lever, a shovel arm connecting lever and a rocker connecting lever. The shovel connecting lever is connected to the excavator shovel via a shovel connecting joint. The shovel arm connecting lever is connected to the shovel arm via a shovel arm connecting joint. The rocker connecting lever is connected to the shovel connecting lever via a shovel rocker connecting joint and to the shovel arm connecting lever via a shovel arm rocker connecting joint. The shovel connecting joint and the rocker connecting joints are arranged such that the rocker connecting lever is displaceable between a shovel lifting position and a shovel delivery position through a dead center position, defined by the shovel connecting joint and a rocker connecting joint.
US11135522B2
A vertical wind tunnel for raising persons by use of air flow, comprising a flight platform (1), an air flow generating device (2) associated with the flight platform (1) and generating a vertical air flow through a channel (3) arranged in a middle of the flight platform (1). The flight platform (1) comprises a safety mattress (4) positioned around the channel (3); a net assembly (5) comprising a flexible net ring (6) and a net (7). The flexible net ring (6) is positioned around the channel (3) and above the safety mattress (4). The vertical wind tunnel further comprises an upholstery ring (8) arranged above the flexible net ring (6) for further absorption of impacts. The present invention increases a safety of its users effectively absorbing impacts of falling flyers.
US11135520B2
Methods and systems for content processing are described. In one embodiment, gaming data is received from a gaming source server. The gaming data associated with a game. A content signal is received from a signal source during presentation of programming content. The programming content is associated with the content signal and the game. A determination of whether the content signal includes the trigger is made. The device content is presented using the gaming data. The device content is in synchronization with the presentation of the programming content based on a determination that the content signal includes a trigger. Additional methods and systems are disclosed.
US11135519B2
A non-limiting example game system includes a processor incorporated within a main body apparatus, and the processor creates, based on operation inputs of a player, a game stage by selecting components corresponding to a virtual room and by arranging panels corresponding to the components on a grid-shaped arrangement area. In the virtual room, a passage, a stairs, a door with lock blocking the passage and a treasure chest are arranged. A key for releasing the door with lock is contained in the treasure chest. The player creates the game stage by connecting all of the passages and the stairs from a start room that a game is started to a room where a boss enemy object is arranged and by taking arrangement of the doors with lock and the treasure chests containing the key into consideration.
US11135508B2
An example of an information processing system includes a vibrator. The information processing system is configured to store a frequency model function representing a model of vibration frequency transition, wherein the frequency model function includes, as variables thereof, a frequency variable representing a frequency for a period in the model and a period variable for that period. The information processing system is configured to determine a value of the frequency variable and a value of the period variable. The information processing system is configured to generate vibration information representing a vibration pattern that is defined by a frequency transition obtained by applying the value of the frequency variable and the value of the period variable to the frequency model function. The information processing system is configured to control vibration of the vibrator based on the vibration information.
US11135506B2
An apparatus for installing and removing glass panels and methods of using the apparatus are disclosed. The apparatus includes a base portion, a back support structure secured to the base portion, and a glass adjustment system moveably coupled to the back support structure. Methods for using the apparatus to install and remove glass panels from, for example, ice rink boards, are also disclosed.
US11135505B2
A smart mirror can show live or recorded streaming video of an instructor performing a workout in a package that is attractive and unobtrusive enough to hang in a living room. The smart mirror includes a mirror surface with a fully reflecting section and a partially reflecting section. A display behind the partially reflecting section shows the video when the smart mirror is on and is almost invisible when the smart mirror is off. The smart mirror also has a speaker, a microphone, and a camera to enable a user to view the video content and interact with the instructor. The smart mirror may connect to the user's smart phone, a peripheral device (e.g., a Bluetooth speaker) to augment user experience, a biometric sensor to provide biometric data to assess user performance, and/or a network router to connect the smart mirror to a content provider, an instructor, and/or other users.
US11135502B2
A motional state of a player in a video displaying the player in motion is easily determined. This player state display system includes a display device which displays a player video that includes information related to a motional state of the player. A processor generates, based on information that is obtained from an analysis video obtained by capturing the player in motion, a player state display image obtained by visualizing a movement zone corresponding to at least one predetermined motion of the player, and generates, as the player video, a video obtained by superimposing the player state display image on the video including the player in motion.
US11135500B1
A basketball shot counter includes a mounting shaped and sized to connect the basketball shot counter to a portion of a basketball goal having a basketball hoop; a vibration sensor; a processor in data communication with the vibration sensor, wherein the processor is configured to receive, from the vibration sensor, a datastream of vibration sensor readings; determine, from the datastream of vibration sensor readings, that a first basketball shot was attempted without successfully going through the basketball hoop; and determine, from the datastream of vibration sensor readings, that a second basketball shot was attempted and successfully went through the basketball hoop.
US11135498B2
A system for analyzing a putting motion includes: mat markers attached to a mat on which a ball is placed; a putter marker attached to a putter for applying an impact to the ball; a mat having a color contrasting with colors of the mat markers, the putter marker and the ball; a camera for photographing the mat markers, the ball, and the putter marker; a mat detection unit for detecting a position of the mat from an image photographed by the camera; an object detection unit for detecting positions of the putter and the ball in real time; a ball calculation unit for calculating a speed and a moving direction of the ball based on the detected ball; and a pointer calculation unit for calculating a pointer position for a menu selection function necessary for a simulator operation by using coordinates of the detected putter.
US11135496B2
A golf training club has a shaft having a proximal end and a distal end. The shaft defines a longitudinal axis. A club head is coupled to the distal end, the club head having a sole, a club face, and an upper surface. An address alignment gauge extends along the longitudinal axis of the shaft. The club face defines a closed face angle about the longitudinal axis of the shaft with respect to the address alignment gauge that is between about 20 degrees and about 40 degrees. A lie angle between the shaft and ground surface is between about 55 and 75 degrees.
US11135492B2
This disclosure provides a method, a terminal and a running shoe for prompting a user to adjust a running posture. The method comprises: obtaining running posture information of the user in real time; determining a current running status of the user based on the running posture information; and generating a feedback for prompting the user to adjust the running posture based on the current running status of the user. By using the technical solutions of this disclosure, the user can know his/her own running posture and running status intuitively in real time when running, so as to adjust his/her own running posture timely. This not only increases operation convenience of the user but also reduces hurt to knees or feet of the user.
US11135489B2
A three-dimensional golf ball marker for marking a position of a golf ball on a putting green includes a housing with a bottom surface and a spherical cap including a texture selected from the group consisting of golf ball like dimples, smooth, grooved, ridged, rubbery, and polished. The spherical outer surface of the housing may rotate and includes an alignment mark formed around at least part of a diameter of the housing. The three-dimensional golf ball marker may include a removable marking disc, with an alignment mark formed on at least one side, which is retained adjacent the bottom surface of the housing by a magnet or retained within a slot. The three-dimensional golf ball marker may include a wireless location device that transmits a wireless signal to allow a tracking device to determine a location of the three-dimensional golf ball marker and to generate information of the golfer.
US11135482B2
A golf ball with improved durability is disclosed herein. The golf ball has a mantle layer comprising a blend of ionomers and methyl methacrylate, butadiene, styrene (MBS) with a weight percentage of MBS ranging from 5 to 15 weight percent of the mantle layer.
US11135472B2
The present invention relates to a treadmill. The treadmill includes a treadmill frame, an endless belt, a strap member and a retracting device. The strap member is located above the endless belt. The strap member has a first end, a second end, and a middle section. The first end of the strap member is operably connected to a right side of the treadmill frame, and the second end of the strap member is removably connected to a left side of the treadmill frame. The retracting device is configured to retract the strap member into the retracting device when the second end of the strap member is disconnected from the treadmill frame. When the second end of the strap member is connected to the left side of the treadmill, the middle section of the strap member constrains a position of a user on a top surface of the endless belt.
US11135465B1
The exercise vehicle seat cover comprises a vest portion, an apron portion, a seat and leg portion, and a plurality of resistance bands. The vest portion, the apron portion, and the seat and leg portion may couple to a car seat to cover and protect a back cushion and a seat cushion and may detachably couple to each other. The plurality of resistance bands may couple to a plurality of vest grommets, a plurality of seat grommets, or both. The plurality of resistance bands may be adapted for use by a driver to perform a resistance exercise while sitting in a vehicle while stationary. The vest portion and the plurality of resistance bands may be adapted to be removed from the car seat and worn by the driver while the driver is standing outside of the vehicle to exercise while standing.
US11135459B1
A mask includes: an intake valve panel comprising one or more intake valves, the intake valve panel further comprising an intake filter configured to filter the user's intake breath, the intake valve panel positioned in a center of the mask; one or more exhaust tubes, at least one of the one or more exhaust tubes comprising at least one of the exhaust valves, at least one of the exhaust tubes configured to conduct the user's exhale breath through the at least one of the exhaust valves and then out of the mask, at least one exhaust tube holding the at least one exhaust valve tightly while allowing the at least one exhaust valve to open and close freely; and a soft foam lining configured to tightly hold the mask against the user's face.
US11135448B2
Systems and methods for implementing an adaptive therapy workflow that minimizes time needed to create a session patient model, select an appropriate plan for the treatment session, and treat the patient.
US11135446B2
The present invention concerns a medical device (10) intended to be worn by a human wearer, the medical device (10) defining a first area (26) and a second area (28), each area being intended to be positioned in front of a respective eye of the wearer. The medical device (10) comprises a frame (10), comprising a rear shell (34). The rear shell (34) defines a hole (54) facing the first area (26) and the rear shell (34) is opaque facing the second area (28). The medical device (10) also comprises an optical module (20) in the first area (26). The optical module (20) comprises a light source (70) and an optical system (72). The optical module (20) is arranged to send a light beam through the hole (54). The medical device (10) further comprises an electronic circuitry (18), adapted to command the optical module (20).
US11135443B2
System (1) for treatment by photodynamic therapy comprising an illuminating member (6) which comprises: —a core (35) carrying a light emitting surface (37), and —a hollow sheath (10) adapted to receive the core (35) with the light emitting surface (37) arranged within a balloon (11), the balloon (11) comprising a wall (12) which has an inner surface delimiting an internal space, and an outer surface, the wall (12) being flexible, wherein the internal space of the balloon (11) has a variable capacity, the wall (12) of the balloon (11) being elastically extendible and the balloon (11) presenting a plurality of inflated states in each of which the internal space is filled with a volume of light diffusing solution, and wherein the system further comprises a support provided with a transfer function relating the volume of light diffusing solution of each inflated state with at least one of a corresponding distribution of light power at the outer surface of the wall (12) of the balloon (11) and a corresponding time of illumination for providing a determined dose of light energy.
US11135432B2
Systems and methods are provided for optimizing hemodynamics within a patient's heart, e.g., to improve the patient's exercise capacity. In one embodiment, a system is configured to be implanted in a patient's body to monitor and/or treat the patient that includes at least one sensor configured to provide sensor data that corresponds to a blood pressure within or near the patient's heart; at least one adjustable component designed to cause blood to flow in a direction opposite to the normal direction (regurgitation) within the patient's heart; and a controller configured for adjusting the function of the at least one adjustable component based at least in part on sensor data from the at least one sensor.
US11135431B2
An implantable medical device (IMD) includes multiple stimulation engines for independently stimulating respective electrode sets of a lead system while avoiding collisions and/or channel contention during stimulation delivery. A first voltage multiplier is configured to generate an adjustable target voltage having sufficient headroom at an output node that is commonly coupled to anodic nodes of respective stimulation engines. Each stimulation engine includes a secondary voltage multiplier to drive the respective anode and a current regulator powered by a floating voltage supply, wherein the current regulator is coupled to a cathodic node and configured to control how much stimulation current is pulled from the patient tissue.
US11135429B2
Techniques are described to determine a location of at least one oscillatory signal source in a patient. Processing circuitry may determine expected electrical signal levels based on a hypothetical location of the at least one oscillatory signal source. Processing circuitry may determine the electrical signal levels and determine an error value based on the expected electrical signal levels and the determined electrical signal levels. Processing circuitry may adjust the hypothetical location of the at least one oscillatory signal source until the error value is less than or equal to a threshold value, including the example where the error value is minimized.
US11135419B1
A method, apparatus and computer system product for improving cardiac output from the heart is presented. A balloon is placed within a chamber of a heart wherein the balloon encloses a mechanical expansion device and air. During a first time epoch in which the heart chamber is volumetrically contracting (during emptying), a mechanical expansion device causes the balloon to increase in size, which improves ejection fraction. During a second time epoch in which the heart chamber is volumetrically expanding (during filling), the mechanical expansion device causes the balloon to decrease in size, which improves filling.
US11135417B2
A medical valve which is able to more reliably support an outer peripheral part of an elastic valve body with respect to a housing, and prevent a problem of the elastic valve body becoming dislodged inward. A medical valve includes an elastic valve body with annular grooves formed thereon and a tubular support part formed at an outer peripheral side of an annular joining part positioned between the annular grooves. Inside and outside holding parts engage the annular grooves provided to the valve inside and outside surfaces of the annular joining part. The outside holding part and inside holding part are provided to an opening member, and with the tubular support part, a part projecting inward in an axial direction is sandwiched and supported between the inside holding part and outside holding part.
US11135416B2
An example of a method of enabling medical fluid transfer between a source container and a destination container can comprise the steps of providing a closed-system fluid transfer module comprising a first closeable, resealable medical connector and a second closeable, resealable medical connector, a multidirectional fluid control valve with a driving interface configured to interface with an electromechanical driver of an electronic medical fluid transfer device, and an intermediate container or an intermediate pumping region; and instructing a user to couple the closed-system fluid transfer module to the electronic medical fluid transfer device.
US11135414B2
Disclosed are medical devices that incorporate siRNA. In addition to one or more siRNA constructs, devices include nanostructures fabricated on a surface to form a nanotopography. A random or non-random pattern of structures may be fabricated such as a complex pattern including structures of differing sizes and/or shapes. Microneedles may be incorporated on devices. The pattern including nanostructures may be formed on the surface of the microneedles.
US11135391B2
Condensation or “rain-out” is a problem in breathing circuits and especially neonatal breathing circuits. The subject patent provides an improved breathing tube component for managing rain-out particularly in neonatal applications. In particular the breathing tube has a smooth inner bore, and an outer insulating layer containing stagnant gas and a heater wire.
US11135386B2
An air delivery system for providing a supply of air from a source of air at positive pressure to an interfacing structure located at the entrance to the airways of a patient includes a manifold adapted to connect with the supply of positive air pressure and at least one tube connected to the manifold and adapted to deliver the supply of air to the interfacing structure. Each tube is structured to allow movement between an open phase in which the tube allows the passage of air and a collapsed phase in which the tube is collapsed. Each tube is structured such that weight of a typical patient's head against bedding apparel is sufficient to collapse the tube from the open phase to the collapsed phase.
US11135382B2
A medical device is provided with an alarm organization. A process for alarm organization of a medical device is also provided. Based on pressure measured values and flow measured values and with a comparison criterion, it is determined whether an elevation of an airway pressure of an anesthesia device or of a ventilator is caused by a coughing event. A visual and/or acoustic output of a warning or alarm is adapted, indicating the elevated airway pressure PAW_High.
US11135381B2
A patient interface mask for use with a breathing assistance apparatus includes a seal that, in use, circumscribes a nose, mouth, or nose and mouth of a patient and defines an interior space of the mask. The mask includes an inlet into the interior space and an outlet from the interior space. A sensor is positioned outside of the interior space and in the path of exit gases exiting the interior space through the outlet. The sensor detects a parameter of the exit gases, such as temperature, humidity or both.
US11135366B2
An ambulatory medical device can detect a device condition and determine if the device condition satisfies a set of normal operating parameters. If the normal operating parameters are not satisfied, the ambulatory medical device can determine if the device condition stratifies a set of minimum operating parameters. If the minimum operating parameters are satisfied, the ambulatory medical device can maintain a delivery of therapy to a subject and generate an alert based on the device condition.
US11135364B2
Systems and methods are disclosed herein for monitoring the status of an ambulatory medical device and the health condition of a subject that receives therapy from the ambulatory medical device. The ambulatory medical device can have a touchscreen display user interface to receive input signals from a user and display alarm conditions associated with the status of an ambulatory medical device or health condition of a subject. The disclosed methods and systems can determine whether status information received from a monitoring system interface satisfies an alarm condition for the ambulatory medicament device or for the subject. If the status information satisfies an alarm condition, the touchscreen user interface can display one or more alarm status indicators corresponding to the alarm condition. The user can activate a therapy change interface on the touchscreen display and modify a control parameter of the ambulatory medical device that controls the therapy delivery to the subject.
US11135363B2
Systems and methods relate to an ambulatory medicament device that can generate a dose control signal to cause a medicament pump to infuse medicament into a subject. The system can analyze status to determine whether an alarm condition for the ambulatory medicament device or for a subject is already present in a list of pending alarm conditions. If the alarm is not present, the system can determine a severity level of the alarm condition from among a plurality of severity levels and annunciate the alarm condition using one or more annunciation patterns selected based on the severity level of the alarm condition for the medicament device or for the subject. The system may maintain an indication of the alarm condition on the list of pending alarm conditions until the alarm condition is resolved.
US11135350B2
The disclosure relates to a system of circumferentially (preferably helically) arranging indicia on the elongate body of a medical device such as a catheter. The disclosure also relates to an anchor drain for securing a surgical drain to a fluid collection device. The anchor drain resists disconnection of the surgical drain from the fluid collection device and also resists occlusion of the conduit connecting the surgical drain and the fluid collection device, even when a suture is tied about a portion of the anchor drain inserted within the surgical drain, and resists unintentional withdrawal of the surgical drain from the body or a body cavity.
US11135342B2
New and useful systems, apparatuses, and methods for providing negative-pressure therapy with instillation of topical treatment solutions are described. An apparatus may comprise an exudate container, a solution source, and a pneumatically-actuated instillation regulator. The instillation regulator may be coupled to the exudate container and to the solution source, and negative pressure from a negative-pressure source can actuate the instillation regulator. In some embodiments, a negative-pressure source may be configured for a negative-pressure interval and a venting interval, and the instillation regulator can be configured to draw instillation solution from the solution source during a negative-pressure interval and to instill the solution to a dressing during a venting interval.
US11135340B2
The presently disclosed subject matter provides a coating composition which allows for the co-delivery of two or more bioactive agents with independent control of loading level and release profile for each bioactive agent, an implantable medical device coated with the coating composition, and methods for preparing the coating composition.
US11135339B2
An orthopaedic implant comprising a titanium substrate having silver deposited thereon, wherein the silver is operable to be eluted at a rate of at least 0.25 μg/cm2 24h-1, for at least 14 consecutive days, in use. The invention also extends to a method of producing an orthopaedic implant and use of the same.
US11135333B1
A pathogen disinfection fan system includes a fan having blades or other motive device to induce airflow in a particular direction and a motor coupled to the fan. The motor configured for rotating the fan blades or motive device to induce the airflow in the particular direction. The system further includes a ceiling mount and a connecting member connecting the ceiling mount to the fan and motor. Further, the system includes a pathogen disinfection apparatus mounted to the connecting member. The apparatus including at least one ultraviolet (UV) light source configured to emit UV light having a mean peak wavelength between 200-280 nanometer in a target volume, in a substantially horizontal path substantially normal to the direction of the induced airflow to at least partially inactivate pathogens exposed to the emitted UV light in the path of the emitted light in the target volume.
US11135332B1
A system for chemosensory disorder testing includes a scanner for scanning a unique identifier associated with a test subject. A scent dispensing unit dispenses a predetermined scent for the test subject responsive to receipt of a dispensing control signal. A user interface receives a test response input from the test subject based on a perception of the test subject of the predetermined scent dispensed by the scent dispensing unit. A central controller generates the dispensing control signal responsive to the unique identifier scanned by the scanner. The central controller further determines at least one of a pass test result or a fail test result responsive to a comparison of the test response input to a predetermined response associated with the predetermined scent. A relational database stores the pass test result or the fail test result at a location associated with the unique identifier associated with the test subject.
US11135328B2
Embodiments of the invention relate generally to disinfection and, more particularly, to methods, devices, and systems for disinfection of a space. In one embodiment, the invention provides a disinfecting system comprising: a disinfecting composition; and a device for producing a fog of the disinfecting composition, the fog comprising liquid droplets having diameters between about 0.5 micron and about 20 microns. In some embodiments, the invention includes a dehumidifying device for removing the fog of the disinfecting composition from the space.
US11135318B2
Provided herein are curcumin analogues that are able to interact with amyloid beta (Aβ) and to attenuate the copper-induced crosslinking of Aβ. Also provided herein are methods of using the compounds as imaging agents of amyloid beta and for the treatment of diseases associated with amyloid beta. Methods of preparing unlabeled and radiolabeled compounds useful for interacting with amyloid beta and pharmaceutical compositions are also provided.
US11135314B2
The present invention relates to compositions, kits and methods for making and using RNA compositions comprising in vitro-synthesized ssRNA inducing a biological or biochemical effect in a mammalian cell or organism into which the RNA composition is repeatedly or continuously introduced. In certain embodiments, the invention provides compositions and methods for changing the state of differentiation or phenotype of a human or other vertebrate cell. For example, the present invention provides mRNA and methods for reprogramming cells that exhibit a first differentiated state or phenotype to cells that exhibit a second differentiated state or phenotype, such as to reprogram human somatic cells to pluripotent stem cells.
US11135313B2
A composition comprising at least one AAV vector formulated for intrathecal delivery to the central nervous system is described. The composition comprises at least one expression cassette which contains sequences encoding an immunoglobulin construct linked to expression control sequences therefor and a pharmaceutically acceptable carrier. The immunoglobulin construct may be an immunoglobulin modified to have decreased or no measurable affinity for neonatal Fc receptor (FcRn).
US11135307B2
The present disclosure relates generally to antibody-drug conjugates comprising peptide-containing linkers and to methods of using these conjugates as therapeutics and/or diagnostics. Also disclosed herein are peptide-containing scaffolds useful to conjugate with a targeting moiety (e.g., an antibody), a drug, or both to produce the antibody-drug conjugates.
US11135306B2
An antibody-drug conjugate (ADC) has a structure represented by Formula (I): [D2-L2-Cn2yG2-Ab-Sg1G1-L1-D1]x Formula (I) or a pharmaceutically acceptable salt thereof, wherein Ab is an antibody without glycans (i.e., the protein portion of an antibody); G1 and G2 are glycan moieties, which may be the same or different; Cn1 and Cn2 are conjugation moieties, which may be the same or different; L1 and L2 are linker moieties, which may be the same or different; D1 and D2 are drug units which may be the same or different; and x and y are independently an integer from 0 to 8, provided that x+y≠0.
US11135298B2
The present invention relates to compounds of Formulas I-IV and compositions comprising same, including pharmaceutical compositions. The compounds of Formulas I-IV represent new salt forms of specialized pro-resolving mediators (“SPMs”) which include lipoxins, resolvins, protectins, and their aspirin-triggered counterparts. The SPM salts described here contain at least one or two SPM molecules ionically bound to at least one basic function that is provided by a scaffold as described in Formulas I-IV. Also provided are methods for pharmaceutical and non-pharmaceutical uses of such compounds and compositions describing same.
US11135296B2
Pharmaceutical compositions and dosage forms of (N,N-diethylcarbamoyl)methyl methyl (2E)but-2-ene-1,4-dioate and/or methyl 4-morpholin-4-ylbutyl (2E)but-2-ene-1,4-dioate, containing low levels of certain impurities are disclosed.
US11135280B2
Provided herein are methods of incorporating substitutions of specified residues into a filovirus GP in order to increase immunogenicity and/or broaden the cross-reactivity of the protective immune response against other filovirus members. Also provided herein are mutant filovirus GPs comprising such substitutions.
US11135277B2
The invention provides peptide vaccines comprising the signal peptide domain of selected target antigens of intracellular pathogens. The peptide vaccines of the invention contain multiple class II and class I-restricted epitopes and are recognized and presented by the majority of the vaccinated human population. The invention provides in particular anti tuberculosis vaccines. The invention further provides compositions comprising the vaccines as well as their use to treat or prevent infection.
US11135274B2
Compositions for modulating the expression of a protein in a target cell comprising at least one RNA molecule which comprises at least one modification 5 conferring stability to the RNA, as well as related methods, are disclosed.
US11135270B2
A medicament for preventing or treating heart failure containing an antagonist of the corticotropin releasing hormone receptor 2 as an active ingredient.
US11135264B2
The present invention relates to pre-formulations comprising: a) at least one di-acyl lipid; b) at least one phospholipid; c) at least one biocompatible, organic solvent; d) an alkyl ammonium EDTA salt; and e) at least one somatostatin receptor agonist; wherein the pre-formulation has a water content in the range of 0 to 1.0 wt %. The invention further relates to methods of treatment comprising administration of such pre-formulations, to pre-filled administration devices and kits containing the formulations, to the use of an alkylammonium EDTA salt to reduce the decomposition of the lipid components and/or any active agent contained within the pre-formulation.
US11135260B2
A composition is provided for promoting skeletal muscle oxidative muscle fiber generation. The composition comprises a Lycium barbarum water extract. The Lycium barbarum extract comprises polysaccharide, Lycium barbarum flavone, carotenoid, polyphenol, and Lycium barbarum pigment. The composition may further comprise one or more pharmaceutically acceptable excipients selected from such as a solvent, a co-solvent, an emulsifier, a preservative, a buffer, a protein powder, or a combination thereof. The composition may be used as medicine, functional product, or food supplement.
US11135259B2
Compositions for improving erectile function or treating erectile dysfunction include active ingredients of Muira Puama extract, Quercetin, Chlorophytum borivilianum (Safed Musli), Dimethylethanolamine (DMAE), niacin, Tribulus terrestris extract, alpha-lipoic acid, Horny Goat Weed (Epimedium grandfiflorum), Panax ginseng, and saw palmetto berry extract, and may also include magnesium aspartate, Zinc oxide, and Maca root (Lepidium meyenii). Additional active ingredients include Avena sativa extract (oat straw), L-Taurine, L-Lysine hydrochloride (HCl), a L-Arginine, and/or L-Carnitine.
US11135257B2
In a multi-step process for selectively purifying various pharmacologically-relevant components of a source plant such as cannabis, an initial step of the process provides a low-temperature, robust essential oil/terpene capture that also dehydrates and decarboxylates the starting product—fresh raw cannabis—by means of a vacuum-assisted microwave distillation process. By doing the terpene capture under vacuum distillation temperature may be kept low. The low distillation temperature maximizes yields of thermally-sensitive components such as terpenes and cannabinoids. The process includes additional steps of: extract cannabinoids from the dehydrated cannabis to produce a crude extract via a supercritical CO2 extraction process; purify crude extract of fats, lipids, plant material; and distill relevant cannabinoids from the purified crude extract via a wiped-film process. Selected terpenes and cannabinoids are then recombined in predetermined proportions to achieve extracts of unusual purity and having targeted therapeutic profiles.
US11135248B2
Provided herein are stem cells and methods for producing a culture of stem cells from urine. The stem cells may be differentiated into an osteogenic, chondrogenic, adipogenic, endothelial, neurogenic or myogenic lineage. Methods of use of the cells are provided, including methods of treating a subject in need of a cell based therapy.
US11135237B2
Lipophosphonoxins of general Formula I are described, in which R1 is C8-C22, preferably C10-C18 and more preferably C12-C16 alkyl, or hexadecyloxypropyl, tetradecyloxypropyl, tetradecyloxyethyl or hexadecyloxyethyl, R2 is uracil, thymine, or cytosine, and R3 is selected from a group which contains compounds of general formulas II and III.
US11135229B2
Methods, compositions and systems are presented to deliver estradiol benzoate to an animal so as to sterilize the animal. A physiologically acceptable oil or other carrier in a capsule is used to deliver the estradiol benzoate. The estradiol benzoate is delivered intraperitoneally, intramuscularly, or subcutaneously to a companion or livestock animal.
US11135219B2
This document relates to methods and materials for treating a mammal having a Zika virus (ZIKV) infection. For example, a composition including one or more non-nucleoside RNA polymerase inhibitors can be administered to a mammal having, or at risk of developing, a ZIKV infection to treat the mammal
US11135218B2
Described herein are compounds, compositions and methods for treatment of cancer. Also described are methods and uses for identifying subject with cancer that are suitable for treatment with the compounds, composition and methods are described herein. In one aspect of the present invention, there is provided a method of treating a subject having a cancer deficient in NMT2, comprising: administering to said subject an NMT inhibitor.
US11135217B2
The present invention offers the manufacturing method of the solid formulation wherein the standard deviation of the active ingredient content in the solid formulation becomes 5% or less by mixing the excipients which have a median particle size of 15 or more times, preferably 20 times or more to the median particle size of an active ingredient.
US11135213B2
The present invention provides novel compounds that are quinoline foldamers. Such foldamers stabilize and bind to islet amyloid polypeptide (IAPP). In certain embodiments, the quinoline foldamers of the invention are soluble and cross biological membranes without cellular assistance. The present invention further provides novel method of preventing or treating diabetes in a subject in need thereof by administering to the subject an effective amount of at least one quinoline foldamer of the invention. The present invention further provides novel method of preventing or treating a neurodegenerative disease caused by a misfolded and/or unstructured protein in a subject in need thereof by administering to the subject an effective amount of at least one quinoline foldamer of the invention.
US11135210B2
Compounds are provided that are useful as immunomodulators. The compounds have the Formula (I) including stereoisomers and pharmaceutically acceptable salts thereof, wherein R1, R2a, R2b, R2c, R3, R4, R5, R6a, R6b, m and n are as defined herein. Methods associated with preparation and use of such compounds, as well as pharmaceutical compositions comprising such compounds, are also disclosed.
US11135191B2
The invention features a pharmaceutical suspension containing drug particles, a drug delivery device anchored in the mouth for continuously administering the pharmaceutical suspension, and methods of their use.
US11135186B2
The invention provides compounds for activating the activating transcription factor 6 (ATF6) arm of the unfolded protein response (UPR), or activating the transcriptional targets of ATF6, in the endoplasmic reticulum of a cell, the compounds being of any of formulas (I) through (IX) as described herein. The compounds can be used for treatment of conditions involving gain-of-toxic-function and loss-of-function folding disorders including lysosomal storage diseases, antitrypsin-associated emphysema and similar diseases. These molecules are also expected to have disease-ameliorating effects in Alzheimer's disease and diabetes.
US11135178B2
The invention provides therapeutic methods comprising the administration of thymol or carvacrol, or a pharmaceutically acceptable salt or prodrug thereof. The methods are useful for modulating muscle atrophy, performance, recovery, generation, or maintenance in animals.
US11135176B1
A continuous process for preparing a solid lipid nanoparticle of ibuprofen utilizing hot melt extrusion which avoids additional steps such as high-pressure homogenization, ultrasonication, or solvent evaporation. The continuous process includes preparing a pre-emulsion comprising a lipid, and continuously processing the pre-emulsion through a hot melt extruder device.
US11135170B2
A solid dosage form for injection and a method of making said dosage form wherein the dosage form has a moisture content of 5% (w/w) or less. The solid dosage form comprises a dried matrix including a first excipient and 0.01 to 50% (w/w) or more than 50% and up to 80% (w/w) of a therapeutic peptide; and one or more additional excipients and at least 5% (w/w) of CMC, based on the total weight of the solid dosage form, wherein the dosage form has a width of 0.5 mm to 2 mm.
US11135162B2
The invention relates to a pharmaceutical composition in the form of an aqueous solution, preferably a syrup, containing inosine pranobex and zinc gluconate, characterised in that it contains a sweetener selected from the group of disaccharides, preferably sucrose or/and from the group of polyols, preferably maltitol, a solubilizer from the group of hydroxy alcohols or mixtures thereof, preferably propylene glycol, glycerol, preservatives selected from the group of parahydroxybenzoic acid esters and mixtures thereof, preferably methyl parahydroxybenzoate, propyl parahydroxybenzoate, a sweetener, preferably sodium saccharine or sucralose, and pH regulators in the range from 5.7 to 12.0 preferably aroma, and a method of preparation thereof.
US11135159B2
The present invention relates to an oral enteric high-dose tablet comprising mesalazine as the active substance as well as its use.
US11135136B2
Vinylcyclopropane of general formulae I in which X, Y in each case are O or NH, wherein X and Y cannot have the same meaning, R1 is a linear or branched C1-C8-alkyl radical, which can be interrupted by O, S, an ester group or a urethane group, R2 is a linear or branched C2-C10-alkylene radical, which can be interrupted by O, S, an ester group or a urethane group, R3 is a hydrocarbon radical with 1 to 20 carbon atoms, which additionally can contain one or more N, O or S atoms, and n is 1, 2, 3 or 4, preferably 1 or 2. The vinylcyclopropanes are characterized by a low shrinkage and a high reactivity on radical polymerization and are suitable in particular for the preparation of dental materials.
US11135131B2
A medication bottle includes an outer container wall, an inner container wall and a fluid, such as an aversive liquid, located between the walls. In another aspect, the fluid is located within separate compartments or channels located between the walls where the walls contact or are secured to each other. A further aspect provides a removeable cap including multiple sensors, at least one of which is a biometric sensor.
US11135125B2
A cup holder assembly for a portable and handheld walking apparatus and having a fastener assembly with an annular clasp having an upper edge, defining an annular recess operably configured to selectively increase and decrease in diameter over a portion of a tubular framing structure of a portable and handheld walking apparatus, and having at least one hinge member assembly directly and hingedly coupled to the annular clasp and operably configured to rotate and have a locked position along a rotation path with respect to the upper edge of the annular clasp. A cantilevered support rod is coupled to the at least one hinge member assembly and a cylindrical container member with a container fastener directly coupled thereto and a portion of the cantilevered support rod disposed and compressively retained thereon, the bottom wall and the sidewall defining a cylindrical container cavity.
US11135122B2
Examples of a self-supported device for guiding motions of a target joint of a target body are disclosed. The device comprises a motion generator, a motion transfer system, a target body interfacing system, a load bearing system and a controller. The load bearing system comprises a plate connected to the motion transfer system and a network of joints and links configured to constrain the plate to rotate in three dimensions about a center of rotation of the load bearing system. A position of the center of rotation of the load bearing system being adjustable by adjusting a connection point between the links. The plate of the load bearing system is connected to an adjustable target body interfacing system that is configured to be mounted to the target body. The center of rotation of the load bearing system coincides (or nearly coincides) with a center of rotation of the target joint of the target body.
US11135118B2
A passive range of motion device is disclosed. The passive range of motion device is configured to deliver passive rotational motion to a joint, such as a hip joint. Although the use of passive range of motion devices to deliver postoperative physical therapy to hip or shoulder joints is widespread, these devices deliver motion therapy in only one plane. The hip and shoulder joints, however, allowing motion of the leg or arm in multiple planes. A device for delivering passive range of motion therapy in multiple planes to a joint, such as a hip joint or a shoulder joint, is described. The device may have a processing unit for storing user information and device status information. The device may be controlled by a controller attached to the device, or remotely, such as by a remote desktop computer or a mobile computing device.
US11135111B2
A patient monitoring and repositioning system includes a mattress, a sheet residing on an upper surface of the mattress, a housing containing a drive mechanism, and a sensor adapted to sense a position of a patient resting on the mattress. The drive mechanism is operable to pull the sheet and thereby pull the patient resting thereon. The housing receives the sheet through a slot. In the event that the patient is in an undesirable position on the mattress as detected by the sensor, a controller directs the drive mechanism to pull the sheet so as to pull the patient thereon from the undesirable position to a desirable, predetermined position. The controller may direct the drive mechanism automatically or indicate the undesirable position to a caregiver so that the caregiver may direct the drive mechanism accordingly.
US11135110B2
A patient support apparatus includes a base frame, lift mechanism supporting an upper frame relative to the base frame, a load frame, and a plurality of deck sections, a patient support surface, and a number of barriers positioned about the patient supporting surface. The patient support apparatus includes a notification system for visually notifying a caregiver of a condition or status of a component of the patient support apparatus.
US11135106B2
Disclosed is a tampon applicator package assembly having a tampon applicator and a cap having a closed end and an open end. The tampon applicator has a barrel for housing a pledget and a plunger. The plunger has an end portion that is a cap cover that connects to a remainder of the plunger and mates with the cap at the open end to provide a seal with the cap that completely encloses the tampon applicator in the cap. Also disclosed is an assembly having a tampon applicator, a cap having both a closed end and open end, and a cap cover for covering the open end of the cap. When the cap cover is placed on the open end, the open end is sealed and the tampon applicator is completely enclosed in the cap.
US11135104B2
Diapers adapted for use in the collection of stool samples from infants are disclosed. Such diapers may include a backsheet comprising an effectively liquid impermeable material, a transverse perineal barrier comprising an effectively liquid impermeable material and sealingly connected to another component of the diaper, and a liquid control structure disposed over the backsheet and forward of the transverse perineal barrier. The diaper may include other features adapted to contain exudates, isolate urine from fecal material following discharge, avoid absorption of liquid components of fecal material and enhance likelihood of collecting a fecal sample that is sufficiently representative of its composition immediately following discharge.
US11135101B2
An absorbent article having a longitudinal axis extending in a longitudinal direction and a transversal axis extending in a transversal direction perpendicular to the longitudinal direction. The absorbent article comprises a fluid-permeable topsheet, a lotion on the topsheet having a lotion pattern covering a lotion pattern area, a fluid-impermeable backsheet, and an absorbent core between the topsheet and the backsheet. The core wrap defines a core footprint in a plane parallel to the longitudinal direction and transversal direction. The ratio of the lotion pattern area relative to the area of the footprint of the absorbent core ranges from 5% to 25%.
US11135090B2
Ophthalmic treatment systems and methods of using the systems are disclosed. The ophthalmic treatment systems include (a) a light source device; (b) at least one optical treatment head operatively coupled to the light source device, comprising a light source array, and providing at least one treatment light; and (c) a light control device, which (i) provides patterned or discontinuous treatment light projection onto an eye (e.g., the cornea and/or sclera of an eye); or (ii) adjusts intensity of part or all of the light source array, providing adjusted intensity treatment light projection onto an eye (e.g., the cornea and/or sclera of an eye). The at least one treatment light promotes corneal and/or scleral collagen cross-linking.
US11135084B2
An ostomy bag can include one or more sensors for measuring one or more metrics. An ostomy wafer can also include one or more sensors for measuring one or more metrics. The sensors can be temperature sensors and/or capacitive sensors, for example, and the metrics can include bag fill, leakage, skin irritation, and phase of stoma output, among others.
US11135080B2
A frame assembly includes a first longitudinal member, a second longitudinal member spaced apart from the first longitudinal member, and a plurality of distance maintaining members connected between the first longitudinal member and the second longitudinal member, and configured to maintain a distance between the first longitudinal member and the second longitudinal member.
US11135073B2
A gait assistance apparatus including at least one sensor configured to sense a step motion of a user, and an operator configured to determine assistance forces of a right step and a left step of the user based on step motion information of the user and adjust the assistance force for at least one of the right step or the left step of the user based on a result of proportionally adding together the assistance forces of the right step and the left step based on a variable ratio may be provided.
US11135067B2
Systems, devices and methods for providing orthopedic augments having recessed pockets that receive a fixation material. The orthopedic augments include an outer surface that interfaces with a patient's tissue or bone, an inner surface that interfaces with an implant and having a recessed pocket configured to receive a fixation material, a rim around at least a portion of the recessed pocket, and a port in the rim, wherein the recessed pocket extends along the inner surface in at least a lateral direction from the port.
US11135062B2
Methods, systems, and apparatuses for treating a heart are provided. Methods can include obtaining and using an implant. One or more catheters can be used to properly position and attach the implant in a desired location in a chamber of the heart, for example, on a ventricular wall of the left ventricle between one or more papillary muscles of the left ventricle and the annulus. Then a distance along the implant or a region of the heart, for example, between the papillary muscle and the annulus, can be reduced by contracting the implant along its longitudinal axis by applying tension to a contraction member of the implant. Other embodiments are described.
US11135059B2
Apparatus is provided, including: (A) a valve body (204) including a first frame (206) shaped to define a lumen therethrough, and a valve member (205) disposed within the lumen, (B) an upstream support (210), configured to be placed against an upstream surface of a native heart valve, and (C) a flexible sheet (214) that couples the upstream support to the valve body. The valve body has a compressed state in which the first frame has a first diameter, and an expanded state in which the first frame has a second diameter that is greater than the first diameter. The support includes a second frame (212) that has a compressed state, and an expanded state in which the second frame is annular, has an inner perimeter that defines an opening through the second frame, and has an outer perimeter. Other embodiments are also described.
US11135056B2
A prosthetic heart valve includes an annular frame including a plurality of strut members that is radially collapsible and expandable. A leaflet structure is situated within the frame, and includes a plurality of leaflets having opposing commissure tab portions on opposite sides of the leaflet. Each commissure tab portion is paired with an adjacent commissure tab portion of an adjacent leaflet to form one or more commissures. A commissure support element is positioned at each of the commissures, and comprise a first member and a second member that are separable from each other and configured to receive leaflets therebetween. The first and second members are detached from the frame and spaced radially inwardly from the frame such that the members contact the leaflets radially inward from the frame and limit movement of the leaflets so that they articulate at a location that is spaced radially inwardly from the frame.
US11135055B2
This invention relates to the design and function of a compressible valve replacement prosthesis, collared or uncollared, which can be deployed into a beating heart without extracorporeal circulation using a transcatheter delivery system. The design as discussed focuses on the deployment of a device via a minimally invasive fashion and by way of example considers a minimally invasive surgical procedure preferably utilizing the intercostal or subxyphoid space for valve introduction. In order to accomplish this, the valve is formed in such a manner that it can be compressed to fit within a delivery system and secondarily ejected from the delivery system into the annulus of a target valve such as a mitral valve or tricuspid valve.
US11135049B2
An inferior vena cava filter (340) for use in the inferior vena cava (4) to capture thrombus (8) passing through the inferior vena cava (4) towards the heart and lungs to prevent pulmonary embolism comprises a proximal support hoop (302), a distal support hoop (312) and a plurality of support struts (303) extending between the proximal support hoop (302) and the distal support hoop (312). The filter (340) also comprises a plurality of capture arms (121) which are movable from a capturing configuration to an open configuration. The capture arms (121) are biased towards the open configuration. A biodegradable suture holds the capture arms (121) in the capturing configuration.
US11135042B2
The invention discloses a tooth cleaner mainly composed of a brace and a handle, the brace comprises an upper tooth socket and a lower tooth socket, a plurality of small open holes which are arranged at intervals are distributed in the upper tooth socket and the lower tooth socket, one end of each of the small open holes is connected with a first guide pipe embedded into the brace, the other ends of the first guide pipes extend into the handle and are connected with a pump outlet of a pump module arranged inside the handle, the pump module also comprises a pump air inlet and a pump water inlet, the pump water inlet of the pump module is connected with a water storage module in the handle by a guide pipe, and the pump air inlet of the pump module communicates with an air inlet in the surface of the handle by a guide pipe. By using the tooth cleaner, the problems of poor cleaning and atomizing effects and poor user experience of the original tooth cleaner are solved.
US11135031B2
User interface devices for manipulating a robotic surgical tool in a surgical robotic system are described. A user interface device can includes a device body containing a tracking sensor to generate a spatial state signal in response to movement of the device body. The spatial state signal can be used to control a spatial motion of a surgical robotic system actuator. Several grip linkages can be pivotally coupled to the device body. A grip linkage displacement sensor may monitor movement of the grip linkages relative to the device body, and generate a grip signal in response to the movement. The grip signal can be used to control a grip motion of a robotic surgical tool mounted on the surgical robotic system actuator. Other embodiments are also described and claimed.
US11135030B2
User interface devices for manipulating a robotic surgical tool in a surgical robotic system are described. A user interface device can include a device housing having a gripping surface symmetrically disposed about a central axis. The gripping surface can include a surface of revolution about the central axis. A tracking sensor can be mounted within the device housing to generate spatial state signals in response to movement of the device housing. The spatial state signals can be used to control motion of robotic system actuators. A finger clutch can be disposed at an end of the device housing, and can generate a clutch signal in response to a touch by a user. The clutch signal can be used to pause the motion of the robotic system actuators. Other embodiments are also described and claimed.
US11135024B2
A robotic surgical system is configured to determine whether a surgical instrument has been properly mounted to an arm of the surgical system. As the surgical instrument is moved into engagement with the arm, a magnet on the arm exerts an attractive force on a plate on the surgical instrument. As the instrument engages to the arm, load cell measurements and inertial measurement unit (IMU) information from one or more sensors on the arm are monitored to determine the mass of the instrument as well as the acceleration of the instrument as it mates with the instrument engagement interface. The system compares the load cell measurements and IMU information with what those parameters are expected to be when a surgical device assembly or instrument of that type is mounted. If the load cell measurements and IMU information deviates from what is expected, the system provides a notification to the user and prevents use of the manipulator arm until the surgical device assembly or instrument is properly positioned.
US11135017B2
A method for enhancing a surgical procedure includes providing a three-dimensional model of a patient's organ of a patient based on pre-operative image data of the patient's organ; identifying positional data corresponding to a first position of at least one target treatment anatomy of the patient relative to a second position of an ancillary target anatomy of the patient based on an analysis of the three-dimensional model of the patient's organ of the patient; selecting a puncture location based on the identified positional data; and displaying, by an augmented reality device, a virtual organ object via an augmented reality display system overlaying a real-world environment, the virtual organ object corresponding to the three-dimensional model and visually indicating the selected puncture location.
US11135016B2
The disclosed method encompasses pre-registering an anatomical body part with a coordinate system used by an augmented reality device (such as augmented reality glasses) for outputting (e.g. displaying or projecting) augmentation information. An example of the augmentation information is the position (in the real image captured by the augmented reality device) of a fine registration area on the anatomical body part which a user is supposed to identify for fine registration of the anatomical body part with a tracking coordinate system used by a medical position tracking system. The disclosed method is usable in a medical environment such as for surgery or radiotherapy.
US11135012B2
Embodiments include a system for determining cardiovascular information for a patient. The system may include at least one computer system configured to receive patient-specific data regarding a geometry of the patient's heart, and create a three-dimensional model representing at least a portion of the patient's heart based on the patient-specific data. The at least one computer system may be further configured to create a physics-based model relating to a blood flow characteristic of the patient's heart and determine a fractional flow reserve within the patient's heart based on the three-dimensional model and the physics-based model.
US11135011B2
The device comprises an outer tubular structure (21) having a closed terminal end, and an inner tubular structure (23) positioned in the outer tubular structure (21) and having a side wall with a terminal end and defining an inner volume. A first gap for circulation of a coolant is formed between the outer tubular structure and the inner tubular structure. A light guide (27) is housed in the inner volume of the inner tubular structure (23). The light guide comprises an optical fiber (28) and a diffuser (30) optically coupled to a distal end of the optical fiber. The diffuser is at least partially made of a material diffusing to the electromagnetic radiation conveyed by the light guide, and has a curved shape.
US11134991B2
A stabilization device for bones or vertebrae includes a rod having a rod axis and a plurality of distinct external surfaces that extend parallel to the rod axis, such that for a cross-section of the rod, the distinct external surfaces are arranged at respective angles relative to one another around the rod axis, a bone anchoring device including a receiving part having a channel for receiving the rod and a contact surface for supporting the rod, and a fixation member with a contact surface for fixing the rod in the channel. When the rod is fixed in the channel with the fixation member, the contact surfaces of the receiving part and the fixation member together form surface portions that are shaped to correspond to at least three of the distinct external surfaces, such that the rod is clamped along the at least three distinct external surfaces.
US11134988B2
In an example, a clamping assembly includes a longitudinal member having a first end and a second end, the second end defining a first clamp, a second clamp configured to attach to the first end of the longitudinal member and connect to a rod assembly, a clamping member including a first end, a second end defining a spherical portion, and a third clamp, where the first clamp of the longitudinal member is configured to receive the second end of the clamping member.
US11134982B2
A rapid exchange type medical elongated body is disclosed in which an outer diameter of a distal portion of a tubular member is set smaller than an outer diameter of a proximal portion of the tubular member, which prevents an occurrence of a kink in a physical property change region of the medical elongated body which has a relatively large change in physical property. A tubular member forming a second region of a distal member of a medical elongated body is integrally formed with a shaft portion. The distal member has a reinforcement layer containing a metallic material and formed between an inner layer and an outer layer from a first region to the second region. The reinforcement layer is disposed inside the tubular member in the second region. An outer diameter of the first region is set smaller than an outer diameter of the second region.
US11134981B2
A device for providing access to a nodule, lesion, or pathological area in a lung or other body organ or lumen. The device includes a sheath portion having a proximal end and a distal end and a plurality of stabilization wires. The sheath portion includes a primary lumen that extends from the proximal end to the distal end and a plurality of secondary lumens that extend from the proximal end to the distal end. The stabilization wires are configured to be slidably received within the secondary lumens. The length of the stabilization wires is greater than the length of the secondary lumens.
US11134979B2
A surgical knife safety device having a handle, a blade connected to the handle, and a guard carried by the handle for sliding movement between a retracted position in which the blade is exposed for use, and an extended position for covering the sharp cutting edge of the blade. In the retracted position, an enlarged guard radius is provided at the distal end of the handle to allow improved handle control and blade orientation. The enlarged guard radius is positioned to allow the user to firmly grip a large distal handle portion which is preferably molded as a single piece with the blade holder, preventing unwanted blade or handle movement due to guard mechanism tolerances.
US11134977B2
An ultrasound probe includes a probe body, and a treatment unit. The treatment unit includes: a cutter that is provided at a distal end part of the treatment unit and that cuts the bone according to move of the treatment unit along a longitudinal axis in a state where ultrasonic vibration is being transmitted to the probe body; and a path that is provided in the treatment unit and through which debris of a bone that is cut by the cutter are discharged along the longitudinal axis toward a proximal end side with respect to the cutter. The path includes a first opening that is provided in a distal end surface of the cutter; and a second opening that is provided in a side surface part of the treatment unit, wherein the path allows the first opening and the second opening to communicate.
US11134970B2
A forceps includes jaws, a first shaft having a first slot, a second shaft extending along the first shaft and having a second slot, and a rod that extends along the second shaft. The rod has a third slot including a locking portion and a guide track portion. A pin extends through the first slot, the second slot, and the third slot to prevent deployment of the rod when the pin is in the locking portion and to permit deployment of the rod when the pin is in the guide track portion. A first actuator produces relative movement of the first and second shafts to move the jaws relative to each other and move the pin from the locking portion to the guide track portion of the third slot. A second actuator produces movement of the rod to deploy the rod when the pin is in the guide track portion.
US11134964B2
A device comprises a base. A support is attached to the base. The support is shaped to receive a calf of a person and adapted to receive a wire or pin for securing a tibia of a person. A foot plate is attachable to the base. The foot plate has a plurality of attached members. The members are configured for receiving at least a first wire or pin to fix a foot of the person relative to the foot plate while the foot plate is oriented normal to a superior-inferior direction of the foot. The foot plate is rotatable relative to the base while the foot plate is attached to the base.
US11134959B2
A patient matched instrument is disclosed. The patient matched instrument includes a body having an interior patient matched surface; a cutting slot extending through at least a portion of the body; a first paddle extending from the body; and a second paddle spaced apart from the first paddle and extending from the body; and wherein at least one of the first paddle and the second paddle further comprises a hook.
US11134956B2
A surgical clip applier is provided including a housing, at least one handle pivotably connected to the housing, an outer support channel extending distally from the housing, a drive channel sliadably disposed within the outer support channel, a jaw assembly including a first and second pair of jaws extending from an end of the outer support channel in a parallel configuration, and an integrated cutting mechanism disposed within a gap defined between the first and second pair of jaws. The jaw assembly is capable of effectuating formation of a pair of clips disposed within a respective first and second pair of jaws in response to movement of the at least one handle and the cutting mechanism is independently operable of the at least one handle. At least one jaw member of each of the pair or jaws includes a curved distal end. A method of operating same is also provided.
US11134947B2
A surgical stapling device that comprises an end effector that is configured to receive various control motions from a robotic system.
US11134946B2
A surgical stapler, cartridge assembly, and related methods are disclosed. A cartridge assembly for a surgical stapler has a first cartridge portion; and a second cartridge portion; wherein each of the first and second cartridge portions has an upper surface for engaging tissue, and a slot to house a staple. A proximal portion of each of the first and second cartridge portions has a guide portion having at least one of a channel or a protrusion for guiding at least a portion of an i-beam. The second cartridge portion is removably couplable to the first cartridge portion to form a channel.
US11134941B2
A method is used to manufacture a lower jaw of an end effector of a surgical instrument. The method includes providing a lower jaw that includes a U-shaped body portion. The U-shaped body portion includes a bottom wall interposed between first and second opposing side walls. The method also includes forming at least one feature into at least one of the first and second side walls, wherein the at least one feature has a near net shape. The method also includes subsequently machining the at least one feature to have a machined shape.
US11134939B2
A surgical instrument including a handle portion, a body portion, a movable handle, a tool assembly, a drive beam and a closure apparatus is disclosed. At least one of the closure apparatus and a contact surface of the tool assembly include a plastic surface. The body portion extends distally from the handle portion. The movable handle is located on the handle portion and is in mechanical cooperation with a drive member. The tool assembly includes an anvil, a cartridge assembly and a contact surface. The drive beam includes a proximal engagement portion and is configured to engage a portion of the drive member. The closure apparatus is configured to engage the contact surface of the tool assembly. At least a partial actuation of the movable handle moves the closure apparatus distally into engagement with the contact surface to approximate the anvil and the cartridge assembly.
US11134937B2
Disclosed suture clips include a generally disk-shaped body having an annular outer body, first and second tabs extending radially inwardly from opposing sides of the annular outer body, first and second slots passing through a thickness of the suture clip and separating the annular outer body from lateral sides of the first and second tabs, and the first and second slots include stepped portions configured to align the suture clip on a rail of a clip deployment device. The stepped slots create bracketing surfaces that interface with the rail on which the clips are mounted, such that the bracketing surfaces prevent or limit the freedom of the clips from tilting or shifting relative to the rail. The disclosed clips can also include rounded edges on engagement surfaces of the tabs to minimize particulate formation.
US11134927B2
An endoscopic treatment tool includes a sheath; a treatment portion; and a manipulation main body which includes a distal end-fixing portion capable of being fixed to a proximal end side-opening portion, an intermediate portion connected to a proximal end of the sheath and advances and retracts in a longitudinal axis direction of the sheath, a proximal end-manipulating unit which slides with respect to the intermediate portion, a fixing member, and a support member. One of the distal end-fixing portion and the intermediate portion is inserted and connected to the other thereof to partially overlap each other in the longitudinal axis direction, the support member is rotatably engaged with a member disposed on an outer side among the distal end-fixing portion and the intermediate portion, and the support member is configured to be able to fix the fixing member at an arbitrary-position of the manipulation main body in the circumferential direction.
US11134926B2
Provided is a spiral soft tissue biopsy needle, comprising a puncture needle rod (1), a sampling needle rod (2), and a hand shank (3) for fixing the puncture needle rod (1) and the sampling needle rod (2), wherein the sampling needle rod (2) comprises a spiral needle rod (21) for fixing the sampling site and a cutting needle rod (22) for separating the sample from the sampling site, the spiral needle rod (21) has a hollow structure, the front end of the spiral needle rod (21) is provided with a spring spiral tube (211), and the front end of the cutting needle rod (22) is provided with a cutting edge (221). The spiral soft tissue biopsy needle of the present invention can improve the success rate of one-time sampling and achieve a multi-point sampling in different positions.
US11134925B2
A disposable diaper product useful for collecting a urine sample from an infant is disclosed. In one example the product may have a liquid control structure overlying a liquid impermeable backsheet, with a plan surface area defining a volume coextensive therewith, wherein a portion of the volume defined by at least 50 percent of the plan surface area contains no more than 50 percent by weight absorbent material. In another example the product may have a liquid control structure overlying a liquid impermeable backsheet, and have an average Liquid Release Ratio of at least 3 percent. A method for collecting a urine sample from an infant is also disclosed, in which a diaper is used for collection.
US11134921B2
An ultrasonic diagnostic device and ultrasonic three-dimensional image generation method generate a three-dimensional image by expressing interaction by dispersion, absorption, or the like of light in tissue or between tissues. The ultrasonic diagnostic device displays a three-dimensional image of a target object based on at least one piece of volume data among luminance volume data, blood flow volume data, and elasticity volume data. The ultrasonic diagnostic device includes: a light source setting unit to set light source data indicating characteristics of a light source set in a three-dimensional space; an optical characteristic setting unit to set characteristics of the volume data related to the light source; an illumination calculation unit calculates illumination of coordinates of the volume data based on the light source data and optical characteristics and generate illumination volume data based on calculated illumination; and a projection processing unit generates the three-dimensional image from the illumination volume data.
US11134918B2
A modular array includes modular array includes one or more array modules. Each array module includes one or more transducer arrays, where each of the one or more transducer arrays includes a plurality of piezoelectric elements; a conducting interposer arranged and configured to provide acoustic absorbing backing for the one or more transducer arrays; and one or more Application Specific Integrated Circuits (ASICs). The conducting interposer and the one or more ASICs are in electrical contact with each other at a first direct electrical interface. Additionally, the conducting interposer and the one or more transducer arrays are in electrical contact with each other at a second direct electrical interface.
US11134914B2
Disclosed are ultrasound devices and methods for use in guiding a subdermal probe during a medical procedure. A device can be utilized to guide a probe through the probe guide to a subdermal site. In addition, a device can include a detector in communication with a processor. The detector can recognize the location of a target associated with the probe. The processor can utilize the data from the detector and create an image of a virtual probe that can accurately portray the location of the actual probe on a sonogram of a subdermal area. In addition, disclosed systems can include a set of correlation factors in the processor instructions. As such, the virtual probe image can be correlated with the location of the actual probe.
US11134908B2
Technologies for determining the spatial orientation of input imagery to produce a three-dimensional model includes a device having circuitry to obtain two-dimensional images of an anatomical object (e.g., a bone of a human joint), to determine candidate values indicative of translation and rotation of the anatomical object in the two-dimensional images, and to produce, as a function of the obtained two-dimensional images and the candidate values, a candidate three-dimensional model of the anatomical object. The circuitry is also to determine a score indicative of an accuracy of the candidate three-dimensional model, to determine whether the score satisfies a threshold, and to produce, in response to a determination that the score satisfies the threshold, data indicating that the candidate three-dimensional model is an accurate representation of the anatomical object.
US11134905B2
A device for attaching an x-ray grid holder to a commercial structure such as a pipe so that the modern digital grid can be used in analysis and inspection. The x-ray grid holder attach device is constructed to be attached to a structure and can include a flat grid holder part, the grid holder part having at least one peripheral slot; a structure contact part constructed to be strapped to a structure to be x-rayed, the structure contact part having a key sized to mate with the peripheral slot, the key having a lock constructed to hold the key in the peripheral slot; the structure contact part can a means to attach it to the structure to be x-rayed such as a strap or suction cups.
US11134881B2
A system for detecting an atrial tachyarrhythmia episode includes a medical device having sensing circuitry configured to receive a cardiac electrical signal from electrodes coupled to the medical device and a processor configured to detect an atrial tachyarrhythmia episode in response to a time duration of the cardiac electrical signal classified as an atrial tachyarrhythmia being greater than or equal to a first detection threshold. The processor is configured to determine if detection threshold adjustment criteria are met based on at least the detected first atrial tachyarrhythmia episode and adjust the first detection threshold to a second detection threshold different than the first detection threshold in response to the detection threshold adjustment criteria being met.
US11134879B2
Arrhythmic foci and other driver sites can be mapped using a multi-dimensional catheter. For instance, using a clique of three or more electrodes on the multi-dimensional catheter, an electroanatomical mapping system can identify a maximum bipolar voltage and an average unipolar voltage. The ratio of the average unipolar voltage to the maximum bipolar voltage can be interpreted as an indication of whether a cardiac location is an arrhythmic focus. Alternatively, an evaluation region can be defined about location in the patient's heart. The evaluation includes a plurality of rods, each associated with a respective E-field loop having a respective maximum and minimum amplitude bipole axes, with the rods being defined by the maximum amplitude bipole axes. For a sufficient number of rods within the evaluation region, a focus score for the evaluation region can be computed to reflect rod orientation consistency within the evaluation region.
US11134866B2
A garment including: fabric configured to conform to a body portion of a wearer; at least one front-transverse segmental marker visible on a front exterior surface of the garment in use and extending parallel to a transverse axis of the body portion; at least one rear-transverse segmental marker visible on a rear exterior surface of the garment in use and extending parallel to the transverse axis of the body portion; at least one front-longitudinal segmental marker visible on a front exterior surface of the garment in use and extending parallel to a longitudinal axis of the body portion; at least one rear-longitudinal segmental marker visible on a rear exterior surface of the garment in use and extending parallel to the longitudinal axis of the body portion; and at least one side-longitudinal segmental marker visible on each side exterior surface of the garment in use and extending parallel to the longitudinal axis of the body portion.
US11134863B2
A method to generate orthotic product recommendations for users includes receiving interactions from a user including identification of one or more extremity areas of the user's body, the one or more extremity areas relevant to selection of one or more orthotic products. On-screen cues and interactions are provided to assist in positioning of the one or more extremity areas relative to one or more imaging sensors. Scan data is received from the one or more imaging sensors. A model of the one or more extremity areas is generated based on the scan data including estimating one or more complete circumferences of the one or more extremity areas. One or more orthotic products are identified based on a comparison of the model of the one or more extremity areas and one or more factors associated with the user and a plurality of orthotic products. A recommendation is provided that includes the one or more orthotic products.
US11134862B2
Methods may be provided to identify a medical implant from a plurality of medical implants to be fixed to an anatomical surface. Dimensional parameters for each of the plurality of medical implants may be provided, and dimensional parameters corresponding to the anatomical surface may be provided. The dimensional parameters for each of the plurality of medical implants may be compared with the dimensional parameters corresponding to the anatomical surface, and one of the medical implants may be selected from the plurality of medical implants based on comparing the dimensional parameters for each of the plurality of medical implants with the dimensional parameters corresponding to the anatomical surface. An identification of the medical implant selected from the plurality of medical implants may be provided through a user interface. Related devices and computer program products are also discussed.
US11134858B1
A method of locating a source of vibrational cardiac energy within a human, includes acquiring time synchronized vibrational cardiac data noninvasively from a surface of the human's body with at least three transducer channels. A time-to-frequency transformation is performed on the vibrational cardiac data to obtain a sequence of heart cycle ensemble averaged power spectral density (PSD) estimates. A feature is identified in the PSD estimates. A vernier band (VB) in frequency is established for the feature. The VB portion of the PSI) estimates that correspond to the feature are processed to obtain a vibrational energy intensity level estimate at a spatial location within the human's body. A metric of clinical significance is obtained from the strength of the estimated vibration intensity within a VB and at a location relative to a background noise level.
US11134855B2
An optoelectronic sensor, a control method for the optoelectronic sensor, and a pulse monitor including the optoelectronic sensor. The optoelectronic sensor may include a light source, a first receiver, a second receiver, and a phantom material layer that is facing a light-emitting side of the light source and at least partially overlapping with the second receiver.
US11134848B2
A mobile hyperspectral camera system is described. The mobile hyperspectral camera system comprises a mobile host device comprising a processor and a display: a plurality of cameras, coupled to the processor, configured to capture images in distinct spectral bands; and a hyperspectral flash array, coupled to the processor, configured to provide illumination to the distinct spectral bands. A method of implementing a mobile hyperspectral camera system is also described.
US11134846B2
The various embodiments described herein include methods, devices, and systems for providing ultrasound treatment to a patient. In one aspect, a method for adjusting a magnetic resonance guided focused ultrasound (MRgFUS) treatment plan with a magnetic resonance imaging (MRI) system and an ultrasound system includes: (1) identifying a location in a subject that is to receive treatment; (2) applying pulses of focused ultrasound to the identified location with the ultrasound system in order to modulate a level of naturally occurring hormones; (3) concurrently with applying the pulses of focused ultrasound, acquiring with the MRI system functional image data from the subject; (4) obtaining a series of functional images of the subject using the functional image data, the functional images indicative of the modified neuronal activity; and (5) adjusting one or more parameters of the MRgFUS treatment plan using the reconstructed series of functional images.
US11134837B2
Disclosed is a method for determining an updated visual correction need for designing a new vision correcting device of an individual already having a previous vision correcting device previously designed to correct his/her vision, wherein, in a first step, a previous level of correction of the previous vision correcting device is acquired, in a second step, a current vision acuity parameter of the individual wearing the previous vision correcting device is assessed, and, in a third step, the updated visual correction need is determined based on the previous level of correction of the previous vision correcting device acquired in the first step and on the current vision acuity parameter assessed in the second step. A complementary visual correction need can also be determined.
US11134835B2
A vessel dissector used in conjunction with an endoscope is provided with a lumen for receiving the endoscope; a blunt dissecting tip provided on a distal end of an elongated cannula permitting tissue dissection while viewing internal body structures via an objective lens of the endoscope; and a vessel severing tool extending through at least a portion of the elongated cannula and translatable longitudinally relative to the elongated cannula, and the vessel severing tool comprises an electrode-carrying member translatable circumferentially within an arcuate slot extending through an outer surface of the vessel dissector, wherein the arcuate slot comprises an inner radius, an outer radius and a central radius, wherein the outer radius is greater than the inner radius and the central radius is located between the outer radius and the inner radius so the arcuate slot provides a uniform opening through which the electrode-carrying member can extend and retract.
US11134833B2
A method is provided for reprocessing an internal channel of a medical device with a reprocessing system having a valve, a fluid line fluidly coupled with the valve, and at least one sensor coupled with the fluid line. The method includes performing an actuation of the valve to direct liquid through the fluid line and into the internal channel, and detecting with the at least one sensor a predetermined condition within the fluid line while the liquid is being directed into the internal channel. In response to detecting the predetermined condition, a time duration measured from the actuation of the valve is recorded. The method further includes purging the liquid from the internal channel, and directing liquid through the fluid line and into the internal channel for the time duration.
US11134830B2
Embodiments of the disclosure are drawn to a medical device delivery system. The system may include a shaft having a proximal end and a distal end. The device may also include a visualization system at a distal region of the shaft. The system may further include at least one latching structure configured to extend beyond the distal end of the shaft and retract within the distal region of the shaft and at least one advancement mechanism configured to extend beyond the distal end of the shaft to pull the shaft in a distal direction.
US11134802B2
Disposable three dimensional serving utensils that can be incorporated into a pizza box, a cake box or other container, via incised and scored blanks, from which disposable utensils, such as spatulas and knives, can be formed.
US11134801B2
This invention represents converting a conventional pillow into a therapeutic brio top head pillow in conjunction with a body pillow by creating a base for the pillow embodiment apparatus comprising of assembling two or more pieces, as necessary, of the embodiment and encasing the entire configuration with corpulent materials which would become comparable to a standard/queen conventional pillow along with a body pillow. Each piece of the embodiment comprises a flat face on one side and three tiered layers of bilateral symmetrical configuration from the center toward the outwards-opposing directions laterally. The assembly can be done as a face to face or back to back attachment of each side and encasing with materials. This pillow comprises a soft foam and/or other types of corpulent soft cushion for both the interior embodiment and/or casing. This system and method induces and compliments self adjustments of depth and width of indentation to fit the occiput, which is based on the pressure, size, and weight of a person's head, neck, and body.
US11134798B1
A vison-based self-checkout terminal is provided. Purchased items are placed on a base and multiple cameras take multiple images of each item placed on the base. A location for each item placed on the base is determined along with a depth and the dimensions of each item at its given location on the base. Each item's images are then cropped, and item recognition is performed for each item on that item's cropped images with that item's corresponding depth and dimension attributes. An item identifier for each item is obtained along with a corresponding price and a transaction associated with items are completed.
US11134789B2
Active comfort controlled bedding systems and processes include an air blower assembly for variable climate control. The air blower assembly generally includes a unidirectional air blower configured to flow air to and from a mattress surface overlaying the bucket assembly.
US11134780B2
A chair, such as a conference or office chair, includes a seat support; a backrest support; a storage member formed as a force storage element; and a transmission coupling the seat support with the backrest support which allows a pivoting of the backrest support and the seat support between an upright position and a backwardly pivoted position according to a predetermined sequence of movements. The force storage element is coupled with the seat support and the backrest support such that the predetermined sequence of movements is facilitated and the storage member provides a force restoring in the upright position and wherein the flexibly elastic storage member forms in conjunction at least with a first articulated rotation point of the transmission a kinematic chain.
US11134777B2
A cubicle screen includes a first mounting assembly, a second mounting assembly, a fabric roll, a tensioning mechanism, and a retention mechanism. The first mounting assembly has a first clamp configured to be secured to a work surface and a first mounting post secured to the first clamp. The fabric roll is positionable on the first mounting post and has an inner tube and a fabric rolled about the inner tube. The tensioning mechanism is adapted to prevent rotation of the fabric roll about the mounting post and maintain a desired tension in the fabric. The second mounting assembly includes a second clamp configured to be secured to the work surface and a second mounting post secured to the second clamp. The retention mechanism is adapted to secure an end of the fabric to the second mounting post.
US11134773B1
A desktop workspace that adjusts vertically includes a work surface platform, a base configured to sit on an existing platform, such as a desk, a height adjustable mechanism including at least one set of arms that connect at a pivot point(s) creating a scissoring motion to raise and lower the said work surface platform to various heights. A locking and unlocking mechanism may connect to the height adjustable mechanism. In some cases, the apparatus includes an adjustable mechanism to support items such as a keyboard. In some cases, the apparatus includes elements to raise items such as a monitor to an additional height.
US11134768B2
Disclosed herein are embodiments of hydration bladders that include flexible wall portions along with relatively more rigid structural portions that are shaped to help define the shape of the bladder and can also help a user grip and manipulate the bladder. The structural portions can also support or incorporate other bladder features, such as inlet ports, caps, outlet ports, valves, tubes, attachment points, graphic designs, and/or other features. Some embodiments include an outlet tube that is retractable and extendable through an upper port at the top of the bladder.
US11134745B2
A sole structure for an article of footwear includes a first midsole body and a second midsole body. The first midsole body defines a ground-facing surface and a foot-facing surface opposite the ground-facing surface and includes a first midsole material, which has a first hardness. The second midsole body extends through the first midsole body. As such, the second midsole body extends beyond the ground-facing surface of the first midsole body. The second midsole body includes a second midsole material, which has a second hardness, and the first hardness is greater than the second hardness.
US11134734B2
The present invention describes a muscle enhancement device comprises a pad sandwiched between two pieces of fabric. The pad is surround by a transitional edge. When muscle enhancement device is being worn properly, the muscle enhancement device is changed from a relaxed state to a stretched state and pad provides a soft, comfortable diffused and obscure edge.
US11134733B2
Embodiments of the invention provide a garment liner that couples to the interior of a clothing article. The garment liner can replace typical underwear. The garment liner can shield clothing from a person's body, and can improve comfort by conforming to the shape of the clothing instead of to the body.
US11134731B2
A garment having a protective hood joined to a collar at an attachment point above a neck seam on the collar, the protective hood having a perimeter defining a hood opening, a rigid, transparent visor attached to the protective hood at the perimeter such that the visor is configured to cover eyes during normal wear.
US11134730B1
A cushion used for uniform compression of a surface with varied topography with minimal stress concentrations. The cushion includes a shaped base and a plurality of flexible projections extending from the shaped base. Each of the plurality of projections has a proximal end attached to the shaped base, a distal end opposite the shaped base, and an axial section extending between the proximal and distal ends. The plurality of flexible projections can individually flex. In an aspect, a facial cushion for use with a mask brace that secures a face mask to a patient's face includes a shaped base and a plurality of flexible projections extending from the shaped base. The individually flexing projections provide greater comfort to a wearer of the mask brace because the flexible projections can conform to the structure of the wearer's face while still providing a seal of the face mask to the face.
US11134727B2
The invention features a scented mask system to provide a pleasant smell in an unpleasant environment. The mask is a one-piece stretchable material with openings sized to fit aelliptical the user's ears. The mask becomes fragrant when nestled inside of a pod having an area sized to receive at least one fragrance component such as a fragrant discs or strips which cause the mask to become scented.
US11134726B2
In one embodiment, a neck support device includes: first and second leg attachment portions; a head cradle; and a first coupling portion attaching the first leg attachment portion to the head cradle and a second coupling portion attaching the second leg attachment portion to the head cradle. In another embodiment, a method of supporting the neck of a user when the user is laying on his or her back or supporting the back of a user when the user is in a seated position includes: attaching the first leg attachment portion to the first leg of the user; attaching the second leg attachment portion to the second leg of the user; and fixing the head cradle.
US11134723B2
Far-infrared fibers, and components and uses of the same are provided. The far-infrared fibers can be used together with other optional fibers to provide a product containing far-infrared fibers. The product does not emit harmful radiation and could raise a user's body temperature safely to increase the volume and rate of the user's blood flow without affecting the blood pressure and pulse of the user. Furthermore, the product can be male underpants that can improve male sexual function without affecting the physiological state.
US11134721B2
A power supply unit for an aerosol inhaler includes: a first series circuit; a second series circuit connected in parallel with the first series circuit; a first operational amplifier including a non-inversion input terminal connected to one of a first node and a second node, and an inversion input terminal connected to the other of the first node and the second node; and an adjustment circuit connected to the first operational amplifier and configured to prevent a differential input value of the first operational amplifier from being equal to a potential of a negative power supply terminal of the first operational amplifier or a minimum value acquirable by the first operational amplifier, in a state where a potential of the node connected to the non-inversion input terminal is less than a potential of the node connected to the inversion input terminal.
US11134717B2
An apparatus arranged to heat smokable material to volatilize at least one component of the smokable material has a housing. The housing has a first opening at a first end through which smokable material can pass so as to be received within and removed from the apparatus in use. The housing has a second opening at a second end opposed from the first end. The housing further has a chamber between the first and second openings. At least one heater is arranged within the housing for heating smokable material removably received within the chamber in use. A user can access the chamber through at least the second opening to clean within the apparatus.
US11134712B2
An adjustable breading machine for applying a coating material onto a food product, the machine includes a frame and a breading chamber enclosure through which the food product travels along the food path to receive a coating material. The adjustable breading machine may also include a hopper fixedly connected to the frame to deliver a coating material into the breading chamber enclosure. At least partially within the breading chamber enclosure is a main conveyor and an outfeed conveyor. In a first mode of operation, the outfeed conveyor lies in the food path and receives food product from the main conveyor. The adjustable breading machine includes a drum assembly operatively disposed above the outfeed conveyor having a rotatable drum for transporting food product and coating material to the outfeed conveyor. The adjustable breading machine also includes a drum adjustment assembly for moving the drum assembly between modes of operation.
US11134707B2
The invention is directed to a nanostructured composite material comprising a mixture of at least one metal particle such as iron and a carbon material from biomass such as D-glucose, D-glucosamine hydrochloride or a-cyclodextrin. The invention is also directed to a composition comprising the composite material comprising the composite material and an inorganic salt, and a method for synthesizing the composite material comprising immersing the carbon material into a solution of metal ions, drying the impregnated carbon particle and subjecting the impregnated carbon particle to a carbothermal reduction process. The nanostructured composite material is useful as an oxygen scavenging layer in a multi-layer film which comprises the oxygen scavenging layer and an oxygen barrier layer that retards the permeation of oxygen from an external environment.
US11134706B2
Disclosed are starch-based powdered clouding agents for dry beverage mixes and beverage mixes including such powdered clouding agents. The starch-based powdered clouding agent may consist essentially of retrograded maltodextrin and is substantially free of titanium dioxide. Methods of preparing beverage mixes including such powdered clouding agents are disclosed. The powdered clouding agents may be added to water to form a cloudy solution or to a dry beverage mix that may form a beverage having an opacity substantially the same as a comparable natural beverage when reconstituted with water.
US11134697B2
The present invention discloses a preparation method of instant bone milk, including: washing edible animal bones and then crushing, adding a certain amount composite effect enhancer, performing two high pressure hydrolysis-instantaneous pressure relief in high pressure hydrolysis chamber, collecting liquid-phase materials, performing centrifugation for degreasing, wet sieving, homogenizing, spray drying to obtain powdered instant bone milk. A device for preparation method of instant bone milk comprises a high-pressure hydrolysis tank, a grading conveying pipe and a gas-liquid separator. The instant bone milk prepared by the present invention has stable chemical structure, uniform particle size distribution and regular normal distribution, high protein solubility and good solution stability. And the preparation method has simple process, low cost equipment and good versatility.
US11134693B2
The present invention provides a multi-layered coextruded thermoplastic food casing comprising: at least one thermoplastic porous absorbing layer; and at least one layer having a barrier effect for water vapor and/or oxygen, wherein the at least one layer having a barrier effect for water vapor and/or oxygen has an average layer thickness in a range of from 5 to 60 μm over the entire surface area, wherein the at least one thermoplastic porous absorbing layer comprises as a main component at least one thermoplastic polymer material selected from the group consisting of (co)polyamides and (co)polyolefins, wherein the at least one thermoplastic porous absorbing layer comprises areas having a reduced average layer thickness and areas having a non-reduced average layer thickness, wherein the average layer thickness of the at least one thermoplastic porous absorbing layer in areas having a non-reduced average layer thickness is in a range of from 10 to 200 μm, wherein the average layer thickness in areas having a reduced average layer thickness is lower by 7 to 140 μm and is reduced by a range of from 30 to 85% compared to the areas having a non-reduced average layer thickness of the at least one thermoplastic porous absorbing layer, and wherein both areas having a reduced average layer thickness and a non-reduced average layer thickness comprise pores which are able to absorb a functional additive.
US11134680B2
The invention relates to an aqueous disinfectant for disinfecting inanimate surfaces, a concentrate for producing the application solution, and the use of the disinfectant to eliminate microorganisms. The combination of a plurality of organic acids according to the invention is, surprisingly, a synergistic composition and enables adequate germicidal action. Surprisingly, adequate microbicidal effectiveness against a broad spectrum of microorganisms can thereby be achieved in a short exposure time without further active ingredients.
US11134678B2
A disinfectant formulation is provided imparting a residual biocidal property. The disinfectant formulation is used to treat a surface to impart a film having a capacity to quickly kill bacteria and other germs for at least 24 hours after deposit of the film on a treated surface. The disinfectant formulation comprises a polymer binder, wherein the polymer binder is an oxazoline homopolymer or an extended or a modified polymer based on an oxazoline homopolymer, and a biocidal compound. The disinfectant formulation further comprises a carrier. An article having the disinfectant formulation is provided as well as methods of making, using and applying the disinfectant formulation.
US11134673B2
A game call includes a first resonant member. A second resonant member is telescopically operable within the first resonant member between a plurality of telescopic positions. A harmonic carriage has a body and a reed assembly. The harmonic carriage is slidably operable within the second resonant member. The first and second resonant members and the harmonic carriage are slidably operable relative to one another to adjust a resonant length defined between the reed assembly and a resonating end of the first resonant member.