US10253504B2
A system for securing one or more heating cables to a roof and having one or more apparatuses, each apparatus including a metal base panel and a continuous metal C-shaped channel integrally-formed with the base panel. The channel includes a pair of opposing continuous channel walls creating and surrounding a continuous cavity having a cross-sectional cavity shape substantially identical for at least a majority thereof to the cross-sectional shape of the cable. The channel walls are resiliently flexible to enable receipt of a continuous length of the heating cable within the cavity such that the heating cable is in snug continuous contact with the channel to enhance heat conductance from the heating cable to the base panel.
US10253494B2
A wall construction has a number of spaced upright channel-shaped studs and a number of concrete panels that form an exterior wall. The lower end of the studs are mounted on a concrete foundation member, and are provided with respective lower plates that enable moisture to drain away from the from the lower ends of the studs.
US10253493B2
A reflective particulate composition includes a particulate mixture that includes a particulate substrate, a hardness enhancer and a pigment. The reflective particulate substrate has a hydrophobic coating on the particulate mixture. The composition may have a solar reflectance of 70% or greater. The pigment may include a clay, and the particulate substrate may include a feldspar. A method of making the composition may include mixing the particulate substrate, the hardness enhancer, and the pigment to form a particulate mixture, heat treating the particulate mixture, and coating the heat treated mixture with the hydrophobic coating.
US10253491B2
A leaching tube includes a tube base for burial in the earth to disperse or gather liquids, the tube base having a semi-rigid spiral, or helical, form with spiral, or helical, ribs, and spiral, or helical, openings along the length of the tube, a water permeable covering wrapped around the tube base, and a vertical frame inside the tube. The frame is a pipe frame that supports the spiral tube base and also provides an air conduit for air injection inside the tube. The frame is fixed to the spiral ribs on the top and bottom of the frame. End plates can be fixed to the frame by bridge pieces and pins. Sections of tubes can be connected end to end by bridge pieces and pins. The pins can be pipe pieces that can also provide air connections between the tube sections. One of the end plates can provide an inlet opening for an effluent inlet pipe.
US10253487B2
According to one embodiment, a sanitary washing apparatus includes: a nozzle including a jetting port and configured to squirt water from the jetting port to wash a user's body; a flow channel configured to guide water supplied from a water supply source to the jetting port; an electrolytic cell provided midway along the flow channel and being operable to produce sterilizing water; a heating device provided on the flow channel on upstream side of the electrolytic cell; a nozzle cleaning device configured to clean or sterilize the nozzle with the water heated by the heating device or the sterilizing water produced by the electrolytic cell; and a controller configured to perform control for stopping energization of the heating device or reducing an amount of energization of the heating device when energizing the electrolytic cell.
US10253474B2
The invention provides components, structures, methods, and assemblies for controlling sedimentation and debris flow associated with soil erosion. The invention also provides components, structures, methods, and assemblies that are useful for anchoring fiber rolls along a sloped surface.
US10253472B2
A method for transforming existing ground of a given site into a more stable foundation ground is provided. The method includes the steps of defining an outlined area about a surface of the existing ground, excavating soil throughout the outlined area to a depth extending through layers of different soil types; conditioning the excavated soil by mixing together layers of different soil types homogeneously, including in some cases soil imported from an external source; returning the conditioned soil to the outlined area to fill the excavated depth, and compacting the conditioned soil returned to the outlined area, thereby forming the stable foundation ground of high structural capacity and low compressibility.
US10253466B2
A ground level illumination system such as a road stud comprises a light source (12) positioned below ground level (8). An optics block (9) and a top block (2) transmit light from the source (12) to the exterior, the light rising at a shallow angle as a collimated beam in the top block (2) to emerge at a window (4) above the ground level (8). The window (4) is shaped to refract the light into a beam (16) that descends at a shallow angle relative to the ground level (8). The emerging beam (16) may be used to illuminate road markings (26) formed from luminous paint that can be re-charged by the illumination system. A feedback mechanism (82) can measure reflected light levels to maintain the optimal “charge” in the paint. A further element (84) of the system may also compare the intensity of reflected light at different wavelengths to detect the presence of fog.
US10253463B2
The line striper comprises a material deployment system configured to receive a material from a material source and deliver the received material to a deployment mechanism, wherein the deployment mechanism is configured to apply the received material to a surface. The line striper also comprises a mechanical debris removal system configured to, when actuated, move along an application path ahead of the deployment mechanism such that debris is dislodged from the surface, wherein the mechanical debris removal system comprises a contact mechanism configured to facilitate dislodging of the debris from the surface.
US10253462B1
A concrete patching robot has a multi-axis robotic manipulator mounted on a powered, movable, platform that can be raised and lowered to access the underside of structures that may be substantial distances above the ground, for example, the underside of an elevated highway. The entire assembly is maneuverable under the work area and the platform may be raised to access the concrete. Once the work area is in reach of the arm, the device is able to use numerous tools to complete essential steps to repair the concrete.
US10253448B2
A laundry dryer (2) has a casing, a laundry storing compartment (18) arranged within the casing for receiving laundry (19) to be dried by passing process air (A) through the laundry storing compartment (18), and a heat exchanger (10) for dehumidifying the process air (A) after passing the laundry storing compartment (18). Furthermore, the dryer (2) has a condensate collecting device (30) for collecting condensate formed at the heat exchanger (10), and a removable condensate reservoir (40) for storing condensed water formed at the heat exchanger (10). Moreover, the dryer has a control unit (42) for controlling the operation of the laundry dryer (2), and a pumping and feeding arrangement (36) for pumping condensate collected in the condensate collecting device (30) through an internal line (38) to the removable condensate reservoir (40). The pumping and feeding arrangement (36) is fluidly connected to a draining line (39) for pumping condensate collected in the condensate collecting device (30) selectively through said internal line (38) and/or through said draining line (39). The draining line (39) is adapted to be selectively connected to an external sink for discharging the condensate outside the dryer casing or to the removable condensate reservoir (40) to supply the condensate pumped through the draining line (39) to the removable condensate reservoir (40).
US10253440B2
A laundry system includes a laundry appliance having a front-loading wash chamber in which a first clothes load can be washed and a module above the front-loading wash chamber. The module includes a rotatably mounted wash basket defining a top-loading wash chamber in which a second clothes load can be washed.
US10253438B2
A net includes at least two ropes (2, 4), at least one mesh, wherein at least one corner of a mesh is formed by a knot (15) formed by two of the ropes (2, 4). The knot includes a first and a second opening (6, 8) in the first rope (2) through which the second rope (4) passes, and a first opening (10) in the second rope (4) through which the first rope (2) passes. A part of the first rope (2) is being positioned in the first opening (10) in the second rope (4) being in between the first and second opening (6, 8) of the first rope (2).
US10253431B2
A silicon carbide single crystal includes a spiral dislocation. The spiral dislocation includes a L dislocation having a burgers vector defined as b, which satisfies an equation of b><0001>+1/3<11-20>. The L dislocation has a density equal to or lower than 300 dislocations/cm2, preferably, 100 dislocations/cm2, since the L dislocation has large distortion and causes generation of leakage current. Thus, the silicon carbide single crystal with high quality is suitable for a device production which can suppress the leakage current.
US10253423B2
A three-dimensional porous composite structure comprises a porous structure and at least one carbon nanotube structure. The porous structure has a plurality of metal ligaments and a plurality of pores. The at least one carbon nanotube structure is embedded in the porous structure and comprising a plurality of carbon nanotubes joined end to end by van der Waals attractive force, wherein the plurality of carbon nanotubes are arranged along a same direction.
US10253414B2
A processing system and method for depositing a film on a substrate by liquid phase ALD is disclosed in various embodiments. The method includes providing the substrate in a process chamber, spinning on the substrate a first reactant in a first liquid to form a self-limiting layer of the first reactant on the substrate, spinning on the substrate a second reactant in a second liquid, where the second reactant reacts with the self-limiting layer of the first reactant on the substrate to form a film on the substrate, and repeating the spinning steps at least once until the film has a desired thickness. Other embodiments of the invention further include rinsing the substrate to remove excess first and second reactants from the substrate, and heat-treating the substrate during and/or following the film deposition.
US10253413B2
The invention provides a thin film deposition system and a method, and relates to the field of thin film deposition. The deposition method comprises the following steps: 1) heating metal substrate; carrying out deposition. The method is characterized in the step 1) that a current is conducted into the metal substrate at one end of the growth zone by one electrode, and out of the metal substrate at the other end of the growth zone by the other electrode, so that the metal substrate is heated by the heat emitting of the resistant of the metal substrate itself. According to the method, the quality of the prepared thin film is improved, while the preparation cost of the thin film is reduced. In addition, the consistent double-sided thin films can be easily prepared on two surfaces of the metal substrate by employing the system and method.
US10253406B2
The present disclosure generally relates to methods of electro-chemically forming yttria or yttrium oxide. The methods may include the optional preparation of a an electrochemical bath, the electrodepositon of yttria or yttrium oxide onto a substrate, removal of solvent form the surface of the substrate, and post treatment of the substrate having the electrodeposited yttria or yttrium oxide thereon.
US10253405B2
A Cu—Ni—Si-based copper alloy sheet of the invention has excellent mold abrasion resistance and shear workability while maintaining strength and conductivity, in which 1.0 mass % to 4.0 mass % of Ni is contained, 0.2 mass % to 0.9 mass % of Si is contained, the remainder is made up of Cu and inevitable impurities. The number of the Ni—Si precipitate particles having a grain diameter in a range of 20 nm to 80 nm in a surface layer that is as thick as 20% of the entire sheet thickness from the surface is represented by a particles/mm2, and the number of the Ni—Si precipitate particles having a grain diameter in a range of 20 nm to 80 nm in a portion below the surface layer is represented by b particles/mm2, a/b is in a range of 0.5 to 1.5.
US10253402B2
The invention relates to the use of a sheet made of an aluminium alloy for manufacturing a stamped bodywork or structural part of a motor vehicle body, also referred to as a “body in white”, wherein said sheet has a yield strength Rp0.2 no lower than 60 MPa and a tensile elongation Ag0 no lower than 34%. The invention also relates to a method for making such a stamped bodywork or structural part for a motor vehicle body, made from said sheet and selected in the group including inner panels or linings for car doors, a passenger compartment floor, a boot floor, a spare wheel housing, or even a passenger compartment side.
US10253401B2
A method for relieving residual stress in cast-in-place liners of high pressure die cast (HPDC) engine blocks to prevent cracking in the liners during the machining process. The method includes locally heating up the liners and the surrounding engine block material through rapid induction heating and then cooling down the liners and surrounding engine block material with still ambient air to a predetermined temperature after the residual stress has been reduced to a desired threshold.
US10253398B2
The high-strength steel for steel forgings according to the present invention has a composition that includes, as basic components, C: 0.35 mass % to 0.47 mass %; Si: 0 mass % to 0.4 mass %; Mn: 0.6 mass % to 1.5 mass %; Ni: more than 0 mass % up to 2.0 mass %; Cr: 0.8 mass % to 2.5 mass %; Mo: 0.10 mass % to 0.7 mass %; V: 0.035 mass % to 0.20 mass %; Al: 0.015 mass % to 0.050 mass %; N: 30 ppm to 100 ppm, and O: more than 0 ppm up to 30 ppm, the balance being Fe and inevitable impurities. The metal structure is mainly bainite, martensite or a mixed structure of bainite and martensite. Among cubic B1-type precipitates, the number of coherent precipitates having a diameter equal to or smaller than 30 nm is equal to or smaller than 50/μm2.
US10253393B2
Method for heat treating magnetic wire includes a wire supply unit, a wire property measuring unit, a wire tensile force measuring unit, a heat treatment unit, and a wire winding unit. The wire supply unit includes a supply bobbin, a supply rotary part, a wire reel, and a tension roller. The wire property measuring unit includes a size measuring device, an after measurement capstan, and a wire reel and measures a size of the wire prior to the heat treatment. The wire tensile force measuring unit includes a tensile force measuring device, a tension roller, and a wire reel. The wire heat treatment unit includes a heat treatment furnace, a temperature measuring device, an after heat treatment capstan, and a wire reel. The wire winding unit includes a winding bobbin, a winding rotary part that rotates the winding bobbin, a tension roller, and a wire reel.
US10253388B2
The present invention provides: a steel sheet capable of manufacturing a formed product having superior bendability and ultra-high strength when compared with conventional steel sheets for manufacturing a hot press formed product; the formed product having superior bendability and ultra-high strength by using the same; and a method for manufacturing the same.
US10253387B2
A hot-pressed steel sheet member includes a specific chemical composition and further includes a steel structure in which an area ratio of ferrite in a surface layer portion ranging from a surface to 15 μm in depth is equal to or less than 1.20 times an area ratio of ferrite in an inner layer portion being a portion excluding the surface layer portion, and the inner layer portion contains a steel structure represented, in area %, ferrite: 10% to 70%; martensite: 30% to 90%; and a total area ratio of ferrite and martensite: 90% to 100%. A concentration of Mn in the martensite is equal to or more than 1.20 times a concentration of Mn in the ferrite in the inner layer portion, and a tensile strength of the hot-pressed steel sheet member is 980 MPa or more.
US10253386B2
The invention provides a steel sheet for hot press-forming that can reliably give hot press-formed parts having excellent paint adhesiveness, perforation corrosion resistance and joint corrosion resistance, and also provides a method for manufacturing the steel sheet for hot press-forming, and a method for producing hot press-formed parts using the steel sheet for hot press-forming. The steel sheet for hot press-forming includes a base steel sheet and a Zn-based coating layer with a mass of coating of 10 to 90 g/m2 on the base steel sheet, wherein the average ferrite grain diameter in the surface microstructure of the base steel sheet is not more than 20 μm.
US10253384B2
A cold-rolled steel sheet includes, by mass %: C: 0.020% or more and 0.080% or less; Si: 0.20% or more and 1.00% or less; Mn: 0.80% or more and 2.30% or less; and Al: 0.010% or more and 0.100% or less; and further includes: one or more of Nb and Ti which satisfy a requirement of 0.005%≤Nb+Ti<0.030%, in which a structure consists of, ferrite, bainite, and other phases, an area ratio of the ferrite is 80% or more and less than 95%, an area ratio of a non-recrystallization ferrite in the ferrite is 1% or more and less than 10%, an area ratio of the bainite is 5% or more and 20% or less, a total amount of the other phases is less than 8%, an equivalent circle diameter of a carbonitride including one or both of Nb and Ti is 1 nm or more and 10 nm or less, and a tensile strength is 590 MPa or more.
US10253383B2
The present invention is about the design and manufacturing method of constructing nano-structured lattices. The design of the four periodic two-dimensional lattices (hexagonal, triangulated, square and Kagome) is described; and the process of making nano-structured lattices is outlined in the present invention.
US10253381B2
Solid saccharides are produced from an aqueous saccharide solution in a process, where the aqueous saccharide solution is admixed with a carrier liquid in which the saccharides are insoluble and that has a boiling point higher than that of water to obtain an aqueous admixture, and where the aqueous admixture is subjected to an evaporation step. The heat for the evaporation is at least partially supplied by a heated surface area to yield a vapor fraction including water and a residue fraction including solid saccharides and carrier liquid.
US10253378B2
Quantitative analysis method using microorganism 16S rDNA gene having single nucleotide polymorphism
The present invention relates to utilization of an artificially synthesized nucleic acid, and more particularly, to a quantitative analysis method capable of quantitatively adjusting gene-based microbial community analysis results by preparing a microorganism 16S rDNA gene, which has a single nucleotide polymorphism (SNP) at a particular location so as to be differentiated from a gene of a target microorganism on the nucleotide sequence, and then using the microorganism 16S rDNA gene as an internal standard material which is quantifiable through nucleotide sequencing.
US10253376B2
LAMP primer sets for detecting eight mastitis pathogens are disclosed. Methods and kits of using the primer sets to simultaneously detect at least two of the eight mastitis pathogens are also described.
US10253372B2
The present invention relates to the methods and products for detection of colorectal cancer. Additionally, the present invention relates to methods and products for determining the probability, risk or incidence of colorectal cancer and of colorectal cancer metastasis. The products and methods of the present invention include detecting the level of expression of COL10A1 or MMP11, in combination, from samples, including tissue samples, from humans who currently have been diagnosed with cancer or who were previously diagnosed with cancer and those who are thought to have cancer and are undergoing diagnosis.
US10253371B2
A method of treating leukemia in a patient, the method including obtaining a plasma sample from a patient at a first time point and at a second time point, measuring a gene expression level of a set of core clock genes, and at least one of a first set of peripheral clock genes and a second set of peripheral clock genes, each in the plasma sample at the first time point and in the plasma sample at the second time point. Then determining that a first treatment is effective or ineffective for the patient when a correlation of the gene expression level of the set of core clock genes, the first set of peripheral clock genes, and the second set of peripheral clock genes, and treating the patient accordingly.
US10253369B2
Provided are methods of determining whether a subject having ER+ breast cancer is expected to benefit from treatment with combination endocrine therapy and mTOR inhibitor therapy. Also provided are methods of treating a subject having ER+ breast cancer.
US10253366B2
The present invention provides a method for detecting the presence or absence of, or for discriminating between, blood type variants, including RHD*r′s, RHD*DIIIa and RHD*DIVa-2. The method comprises amplifying by PCR a sample obtained from a human subject at intron 3 of the RHD gene locus. The invention also provides products, in particular, probes, primers and kits for use in the method of the invention.
US10253365B1
Provided are compositions and methods for detecting a target DNA (double stranded or single stranded) in a sample. In some embodiments, a subject method includes: (a) contacting the sample with: (i) a type V CRISPR/Cas effector protein (e.g., a Cas12 protein such as Cas12a, Cas12b, Cas12c, Cas12d, Cas12e); (ii) a guide RNA (comprising a region that binds to the type V CRISPR/Cas effector protein, and a guide sequence that hybridizes with the target DNA); and (iii) a detector DNA that is single stranded (i.e., a “single stranded detector DNA”) and does not hybridize with the guide sequence of the guide RNA; and (b) measuring a detectable signal produced by cleavage (by the type V CRISPR/Cas effector protein) of the single stranded detector DNA. Also provided are compositions and methods for cleaving single stranded DNAs (e.g., non-target ssDNAs), e.g., inside of a cell.
US10253364B2
The present disclosure provides compositions, methods, systems, and devices for polynucleotide processing. Such polynucleotide processing may be useful for a variety of applications, including polynucleotide sequencing.
US10253355B2
A system for automated microorganism identification and antibiotic susceptibility testing comprising a reagent cartridge, a reagent stage, a cassette, a cassette, stage, a pipettor assembly, an optical detection system, and a controller is disclosed. The system is designed to dynamically adjust motor idle torque to control heat load and employs a fast focus process for determining the true focus position of an individual microorganism. The system also may quantify the relative abundance of viable microorganisms in a sample using dynamic dilution, and facilitate growth of microorganisms in customized media for rapid, accurate antimicrobial susceptibility testing. Automated quality control test components and methods of their use are also disclosed.
US10253351B2
A method for preserving and processing cell-free nucleic acids located within a blood sample is disclosed, wherein a blood sample containing cell-free nucleic acids is treated to reduce both blood cell lysis and nuclease activity within the blood sample. The treatment of the sample aids in increasing the amount of cell-free nucleic acids that can be identified and tested while maintaining the structure and integrity of the nucleic acids.
US10253348B2
Provided is a method for capture and release of microorganisms using microstructures. The method includes providing microstructures coated with a protein for attachment/detachment of microorganisms, mixing the microstructures with a solution containing substances assisting in attachment of microorganisms in a solution containing microorganisms to prepare a mixed solution, stirring the mixed solution to attach the microorganisms to the microstructures, separating the microorganism-attached microstructures from the mixed solution; and exposing the microstructures to an environment where the substances assisting in attachment of the microorganisms are present at a low concentration to detach the microorganisms from the microstructures.
US10253340B2
Disclosed is a method for the isomerization of glucose by reduction to sorbitol and subsequent oxidation to fructose, in which the redox cofactors NAD+/NADH and NADP+/NADPH are regenerated in a one-pot-reaction, wherein one of the two redox cofactors is obtained in the reduced form thereof and the other redox cofactor in the oxidized form thereof as a result of at least two additional enzymatically catalyzed redox reactions (product forming reactions) taking place in the same reaction batch, wherein a) in the regeneration reaction, which transfers the reduced cofactor back to its originally oxidized form, oxygen or a compound of the general formula R1C(O)COOH is reduced, and b) in the regeneration reaction, which transfers the oxidized cofactor back to its originally reduced form, a compound of the general formula R2CH(OH)R3 is oxidized, wherein R1, R2 and R3 have different meanings in the compounds, characterized in that a mixture of glucose and fructose is used as a starting material. Furthermore, the use of fructose thus produced in a method for producing furan derivatives is disclosed.
US10253338B2
An aspect of the present disclosure is a microbial cell that includes a genetic modification resulting in the expression of a deficient form of an endogenous dioxygenase, and a gene encoding an exogenous dioxygenase and a promoter sequence, where the endogenous dioxygenase includes PcaH and PcaG, the exogenous dioxygenase includes LigA and LigB, the microbial cell is capable of growth utilizing at least one of a cellulose decomposition molecule or a lignin decomposition molecule, and the microbial cell is capable of producing 2-hydroxy-2H-pyran-4,6-dicarboxylic acid.
US10253335B2
The present invention provides a method of producing β-santalene, said method comprising contacting at least one polypeptide with farnesyl pyrophosphate (FPP). In particular, said method may be carried out in vitro or in vivo to produce β-santalene, a very useful compound in the fields of perfumery and flavoring. The present invention also provides the amino acid sequence of a polypeptide useful in the method of the invention. A nucleic acid encoding the polypeptide of the invention and an expression vector containing said nucleic acid are also part of the present invention. A non-human host organism or a cell transformed to be used in the method of producing β-santalene is also an object of the present invention.
US10253333B2
Disclosed herein are polypeptides, polynucleotides encoding, cells and organisms comprising novel DNA-binding domains, including TALE DNA-binding domains. Also disclosed are methods of using these novel DNA-binding domains for modulation of gene expression and/or genomic editing of endogenous cellular sequences.
US10253332B2
The invention relates to the use of a protein with recombinase activity to catalyze a site-specific DNA recombination and a method for producing a site-specific DNA recombination. The invention is applicable alone or in combination with other recombinase systems for genetic manipulation, for example in medical research. The objective of the invention is solved by the use of a protein with recombinase activity to catalyze a site-specific DNA recombination at, preferably at two, recognition sites that are identical or reverse complementary to each other. The invention also includes a method for producing a site-specific DNA recombination comprising the steps of a) providing a cell comprising at least two recognition sites that are identical or reverse complementary to each other; and b) contacting a protein with recombinase activity with the recognition sites, thereby producing the site-specific DNA-recombination.
US10253324B2
Two novel cDNAs for two different genes, HDT1 and HDT2, are isolated from red clover and sequenced. Both HDT1 and HDT2 encode hydroxycinnamoyl-CoA:L-DOPA/tyrosine hydroxycinnamoyl transferase (HDT) which enzymatically produces clovamide and/or related hydroxycinnamoyl amides. Clovamide and related hydroxycinnamoyl amides reduce post-harvest protein degradation. Genetically altered alfalfa plants containing an expression cassette containing a cDNA encoding HDT1 or HDT2 are generated. These genetically altered alfalfa plants produce hydroxycinnamoyl-CoA:L-DOPA/tyrosine hydroxycinnamoyl transferase, which in turn produces clovamide and/or related hydroxycinnamoyl amides.
US10253322B2
Mesocotyl meristem explants that contain multiple primary meristems are transformed via particle bombardment or Agrobacterium-mediated methods. Regeneration is through an organogenesis pathway that allows for secondary multiple bud formation. This method allows for the genotype independent transformation of varieties of wheat.
US10253317B2
Disclosed are particles which are introduced into target cells and suppress the expression of specific genes, and a method of manufacturing such particles. More particularly, the present invention relates to DNA-RNA hybrid particles that comprise a DNA strand and an RNA strand that binds to the DNA strand through partial complementary base pairing, in which the DNA strand comprises an aptamer sequence that is able to bind to a target protein produced in a target cell, and the RNA strand comprises an siRNA sequence that binds to a target RNA in the target cell to suppress protein expression from the target RNA. Such hybrid particles are capable of effectively delivering an siRNA therapeutic agent into target cells for the treatment of disease, and have resistance against digestion by in vivo nucleases, DNase and RNase, owing to complementary binding formed between DNA and RNA strands. Also, the present invention relates to a method of manufacturing such DNA-RNA hybrid particles.
US10253315B2
The present invention concerns a method for in vitro or ex vivo transfection of a nucleic acid into a eukaryotic cell in 3D scaffold by contacting eukaryotic cells in 3D scaffold with a formulation in nanoemulsion form which comprises a continuous aqueous phase and a least one dispersed phase, and which comprises said nucleic acid. The invention further relates to a method of screening implementing said method of transfection, and to 3D scaffold comprising eukaryotic cells and said formulation in nanoemulsion form which comprises a continuous aqueous phase and a least one dispersed phase, and which comprises said nucleic acid.
US10253309B2
The present invention relates to an apparatus for separating fine particles using magnetophoresis, and to a method for separating fine particles using same, and particularly, to an apparatus for separating fine particles using magnetophoresis, which includes a fine, patterned magnetic structure capable of quickly and efficiently separating even particles that are weakly magnetized and coupled to fine particles, and to a method for separating fine particles using same.
US10253306B2
The present invention relates to pharmaceuticals and modified beta-lactamases. Specifically, the invention relates to novel recombinant beta-lactamases and pharmaceutical compositions comprising the beta-lactamases. Also, the present invention relates to methods for modifying a beta-lactamase, producing the beta-lactamase and treating or preventing beta-lactam antibiotic induced adverse effects. Furthermore, the present invention relates to the beta-lactamase for use as a medicament and to the use of the beta-lactamase in the manufacture of a medicament for treating or preventing beta-lactam antibiotics induced adverse effects.Still further, the invention relates to a polynucleotide and a host cell comprising the polynucleotide.
US10253303B2
The present disclosure relates to engineered ketoreductase polypeptides for the preparation of hydroxyl substituted carbamate compounds, and polynucleotides, vectors, host cells, and methods of making and using the ketoreductase polypeptides.
US10253299B2
The present invention relates to a sulfated cellulose hydrate membrane, a method for the preparation thereof and the use of the membrane as adsorption membrane for the purification of viruses.
US10253292B2
System, including methods and apparatus, for identifying and picking spectrally distinct colonies. In an exemplary method, a filter may be received in an optical path extending from a light source to a grayscale image detector. The filter may be configured to increase an intensity difference between a first type of colony and a spectrally distinct second type of colony. Colonies including both types may be received in the optical path. An image of the colonies may be obtained with the grayscale image detector. At least one of the types of colony may be identified in the image. One or more colonies of the at least one type may be picked robotically.
US10253285B2
The present invention a method for simultaneously reducing urethane and its precursors levels during Chinese liquor production process, which relates to the field of fermented food production. The present invention is carried out through inoculating Bacillus amyloliquefaciens JP21 or combines with urease into the grains for fermentation. The content of EC and urea in the fermented grains after 5-day fermentation could reduce 30.16% and 50.05% respectively, With an addition of the B. amyloliquefaciens during grains fermentation, EC and urea levels are successfully controlled, and at the same time aroma and tastes of Chinese liquor hasn't been affected.
US10253284B2
A system or arrangement for making and using a modular keg and bottom is disclosed. The modular keg includes one of a domed bottom or a conical bottom. An improved sealing system is also disclosed to sealably affix the bottom to the keg body.
US10253275B2
Disclosed is a method of treating a used hydrocarbon lubricant of ISO Viscosity Grade 46 or higher comprising oxidation products that adversely affect lubricant performance. The hydrocarbon lubricant has a Group II hydrocarbon oil or Group III hydrocarbon oil, optionally one or more lubricant additives, and an amount of varnish. The hydrocarbon lubricant is free of zinc-containing additives. The method comprises adding to the used hydrocarbon lubricant from about 2 percent by weight to about 20 percent by weight of a polyhydroxy polypropylene oxide homopolymer that has a hydroxyl number of from about 12 mg KOH/g to about 58 mg KOH/g as measured according to ASTM D4274.
US10253264B2
A method of producing low CTE graphite electrodes from needle coke formed from a coal tar distillate material having a relatively high initial boiling point.
US10253263B2
The invention belongs to the field of biomass energy utilization, and a continuous pyrolysis and carbonization method of agricultural and forestry biomass is disclosed. The method comprises the following steps: feeding biomass feedstock to a dryer for drying, then transporting to a continuous pyrolysis apparatus for pyrolyzing to obtain pyrolysis semicoke and pyrolysis volatiles; and transporting the pyrolysis semicoke to a carbonization apparatus for carbonization to obtain biomass charcoal and semi-coke carbonized volatiles; then discharging the pyrolysis volatiles and the semi-coke carbonized volatiles, and cooling to obtain tar, wood vinegar and pyrolysis gas; introducing the pyrolysis gas into a combustion apparatus for combustion to obtain a high temperature flue gas; and finally transporting the high temperature flue gas into pyrolysis apparatus and carbonization apparatus for supplying heat, then the flue gas after supplying heat is delivered to the dryer and discharging tail gas. In the method, continuous and stable pyrolysis and carbonization of biomasses is realized, the pyrolysis step and the carbonization step are finished in the same system with separate step, transport efficiency is significantly increased, reaction conditions are steady and controllable, and the energy utilization efficiency is high.
US10253255B2
Size-tunable phosphorescent particles may be formed through self-assembly of biocompatible linear polymers, such as chitosan and other linear polymers, that bear positive surface charges, through polyelectrolytic complexation to a polyanionic metal phosphor, such as polyanionic gold(I) phosphor (AuP). The phosphorescent hydrogel nanoparticles and thin films thereof are useful for imaging, sensing of biological molecules, detection of hypoxia, and light-emitting devices. The phosphorescent hydrogel particles can be formed from a variety of linear polymers by physical cross-linking using polyelectrolytic light-emitting species, without the need for the phosphorescent complex to be entrapped in an existing microsphere or nanosphere polymer particle.
US10253248B2
Treating fluid compositions for use in hydrocarbon recovery operations from subterranean formations are described, as well as methods for their preparation and use. In particular, treating fluid compositions are described which comprise a liquid, a crosslinkable organic polymer material that is at least partially soluble in the liquid, a crosslinking agent that is capable of increasing the viscosity of the treating fluid by crosslinking the organic polymer material in the liquid, and a crosslinking modifier additive which can delay or accelerate the crosslinking of the treating fluid composition. Such compositions may be used in a variety of hydrocarbon recovery operations including fracturing operations, drilling operations, gravel packing operations, water control operations, and the like.
US10253245B1
A method of preventing formation of a water and oil emulsion in a downhole formation containing oil, the method comprises preparing a dispersion of water and a plurality of nanoparticles, each nanoparticle in the plurality of nanoparticles having a size of at least 300 nanometers, and injecting the mixture downhole into contact with the oil downhole. Presence of the plurality of nanoparticles prevents formation of an emulsion between the injected water and the oil.
US10253239B2
Wellbore fluid compositions containing a base fluid; at least one synthetic fiber; and a particulate solid are provided. In another aspect, methods of reducing loss of wellbore fluid into and strengthening of a formation are provided, including: introducing into the wellbore a fluid composition comprising one or more synthetic fibers and one or more particulate solids.
US10253226B2
A urethane adhesive composition of the present technology contains: a urethane prepolymer having isocyanate groups; and a monosulfide compound which has a monosulfide bond and a hydrolyzable silyl group and in which the monosulfide bond and a silicon atom in the hydrolyzable silyl group are bonded to each other.
US10253221B2
To provide an adhesive excellent in heat resistance and adhesive property. An adhesive comprising a fluorinated polymer having a weight average molecular weight (Mw) of from 6×103 to 3×104 and having iodine atoms at both terminals, and a radical generator. The fluorinated polymer has structural units derived from at least one monomer selected from the group consisting of tetrafluoroethylene, vinylidene fluoride, hexafluoropropylene and a perfluoro(alkyl vinyl ether).
US10253209B2
A paint replacement film comprising a polymer layer comprising a polyurethane produced from a formulation comprising at least one blocked isocyanate. The paint replacement film comprises a liner layer and the formulation comprises at least two polyols in OH weight equivalent ratio in the range 4.5:1 to 1:4.5. The formulation may comprise a colorant and the polyurethane may have a glass transition temperature (Tg) below 42° C. Also disclosed is a method of producing a paint replacement film, by providing a backing layer, providing the liquid formulation, cast-coating the backing layer with the liquid formulation, and gelling the liquid formulation, thereby forming a polymer layer comprising polyurethane. The paint replacement films are useful for replacing paint on surfaces especially in automotive applications.
US10253194B2
There is provided an ink including a pigment, resin particles, a surfactant, water-soluble organic compound, and water, in which: the content of the water-soluble organic compounds is 35 mass % or less based on a total mass of the ink; the water-soluble organic compound contains a first water-soluble organic compound being liquid at 25° C. and having a surface tension at 25° C. of 40 mN/m or less, and the content of the first water-soluble organic compound is 5 mass % or less based on a total mass of the ink; and the surfactant is a surfactant represented by the following formula (1):
US10253184B2
Provided is a composition comprising a) at least one semi-crystalline polyamide, b) at least one conductive material, and c) at least one amorphous polyamide, and optionally d) at least one polyester. The composition may further comprise e) at least one filler and f) at least one additive.
US10253173B2
Provided herein are polymerization processes and polymer compositions including reactor blends formed by such polymerization processes. The polymerization processes include copolymerization using two metallocene catalyst systems: the first catalyst system capable of producing polymers having 60% or more vinyl terminations, the second catalyst system capable of producing high molecular weight polymers, preferably incorporating at least some of the polymers produced by the first catalyst system into the high molecular weight polymers. The reactor blends formed thereby therefore include first and second copolymer components, which may differ in monomer content and weight-average molecular weight (Mw). Furthermore, the reactor blends may exhibit advantageous rheological properties, at least some of which are consistent with long-chain branching. Preferred reactor blends comprise ethylene-propylene-diene (EPDM) terpolymers.
US10253168B2
The invention relates to an additive composition, which comprises a thickener and a thixotropic agent and is characterized in that the thickener is cellulose or a derivative thereof and that the thixotropic agent is a pyrogenically produced silicic acid, the surface of which is modified with groups of general formula (I) —SiRaR1bOR2c (I), in which a can equal 1, 2, or 3, b can equal 0, 1, or 2, and c can equal 0, 1, or 2, wherein a+b+c=3, and R can be a monovalent, optionally monounsaturated or polyunsaturated, optionally branched hydrocarbon group having 1 to 24 carbon atoms, R1 can be a likewise monovalent, optionally monounsaturated or polyunsaturated, optionally branched hydrocarbon group having 1 to 20 carbon atoms, and R2 can be a hydrogen atom, a monovalent, optionally monounsaturated or polyunsaturated, optionally branched hydrocarbon group having 1 to 20 carbon atoms, or a bond to another Si atom, with the stipulation that at least one of the groups R or R1 is a hydrocarbon group having more than 3 carbon atoms.
US10253167B2
The present invention relates to a preparing method of a polyolefin resin mono chip including: forming a thermoplastic resin composite by impregnating a fiber reinforcing agent having a length of 5 mm to 20 mm into a molten mixture including a propylene homopolymer of which a molecular weight distribution Is 3 to 6, and a colorant, wherein a cooling speed at room temperature of the thermoplastic resin composite is 19° C./min or more. In addition, the present invention relates to a polyolefin resin mono chip including: a thermoplastic resin composite including a polymer substrate including a propylene homopolymer of which a molecular weight distribution is 3 to 6, and a colorant; and a fiber reinforcing agent having a length of 5 mm to 20 mm and impregnated into the polymer substrate, wherein an impact strength measured according to ASTM D256 is 200 J/m or more.
US10253165B2
Polymerization processes comprising melt polymerizing a carbonate and a dihydroxy compound in the presence of an amount of a beta organic catalyst so as to give rise to a polycarbonate product, wherein the amount of beta organic catalyst comprises at least one onium salt and also comprises triphenyl phosphonium oxide (TPPO), and wherein the TPPO represents less than about 0.3 weight % of the sum of the weights of the at least one onium salt and the TPPO in the amount of beta organic catalyst.
US10253161B2
Provided is a thermoformed container having a superior appearance as a result of inhibition of coloring and generation of defects during the melt molding, having sufficient strength, and further having a self-purge feature in a production process. The thermoformed container includes an EVOH layer (A) containing an ethylene-vinyl alcohol copolymer (I) as a principal component, wherein the EVOH layer (A) contains a carbonyl compound (II), the carbonyl compound (II) is an unsaturated aldehyde (II-1), a saturated aldehyde (II-2), a saturated ketone (II-3) or a combination thereof, and the content of the carbonyl compound (II) in the EVOH layer (A) is 0.01 ppm or greater and 100 ppm or less. The carbonyl compound (II) is preferably an unsaturated aldehyde (II-1), and the unsaturated aldehyde (II-1) is preferably an unsaturated aliphatic aldehyde.
US10253159B2
The present disclosure provides an aerogel composition which is durable and easy to handle, which has favorable performance in aqueous environments, and which also has favorable combustion and self-heating properties. Also provided is a method of preparing an aerogel composition which is durable and easy to handle, which has favorable performance in aqueous environments, and which has favorable combustion and self-heating properties. Further provided is a method of improving the hydrophobicity, the liquid water uptake, the heat of combustion, or the onset of thermal decomposition temperature of an aerogel composition.
US10253153B2
The present invention provides a linker for solid phase synthesis of nucleic acid, which consists of a compound represented by the formula (I) or the formula (II), a support for solid phase synthesis of nucleic acid, which has a structure represented by the formula (III), and a production method of a nucleic acid, which uses the support: wherein each symbol is as defined in the SPECIFICATION.
US10253147B2
A polymer electrolyte composition has excellent practicality and excellent chemical stability as to be able to withstand a strong oxidizing atmosphere during fuel cell operation and is able to achieve excellent proton conductivity under a low-humidified condition and excellent mechanical strength and physical durability, and a polymer electrolyte membrane, a membrane-electrode assembly, and a polymer electrolyte fuel cell produced therefrom. The polymer electrolyte composition includes an ionic group-containing polymer (A), an azole ring-containing compound (B), and a transition metal-containing additive (C), the transition metal being one or more selected from the group consisting of cobalt, nickel, ruthenium, rhodium, palladium, silver, and gold.
US10253146B2
The disclosure relates to a nanocomposite polymeric film including a thermoplastic polymer matrix such as polypropylene or other polyolefin, a coupling agent-modified organoclay reinforcement, and a polymeric compatibilizer bound to the coupling agent-modified organoclay, in particular as a thin film with controllable thicknesses. The disclosure further relates to masterbatch additives formed from the coupling agent-modified organoclay and the polymeric compatibilizer bound to the coupling agent-modified organoclay as well as related methods for making the nanocomposite polymeric film and/or processing recycled plastics. The inclusion of the coupling agent-modified organoclay reinforcement improves the mechanical properties of the nanocomposite polymeric film and the rheological properties of polymer melts including the nanocomposite polymeric film components. The coupling agent-modified organoclay leads to strain-hardening behavior for the polymer melts, which in turn can improve extensional viscosity values and melt processability for film blowing.
US10253143B2
An object of the present invention is to provide a novel monolayer and multilayer film that can be employed also for use in interior and exterior members of vehicles, and that have excellent transparency, surface hardness, chemical resistance, and stain resistance such as lactic acid resistance and sunscreen resistance. The present invention is directed to a fluororesin film formed with (C) a fluororesin comprising (B) a fluorinated (meth)acrylic resin that contains a fluorine-containing alkyl(meth)acrylate polymer component; and a fluororesin-laminated acrylic resin film, wherein the fluororesin film layer is laminated on at least one face of a film layer comprising (A) an acrylic resin.
US10253141B2
A method for producing a wet rubber masterbatch uses a single-screw extruder. The single-screw extruder includes a screw, and an external cylinder in which a slit extended along the length direction of the external cylinder (the screw-shaft direction) is formed in an internal wall surface of the external cylinder, and when the width of the slit is represented by A and the clearance between a crest of the screw and the internal wall surface of the external cylinder is represented by B, the following expression (1) is satisfied: 0
US10253131B2
Dimethoxyphenol-based monomers containing polymerizable functional groups such as [meth]acrylate groups are useful for the preparation of polymers, wherein one or more dimethoxyphenyl moieties are part of side chains pendant to the backbones of the polymers. The polymers thereby obtained may have different, improved properties, such as higher glass transition temperatures, thermal stability and solvent resistance, as compared to polymers based on other types of lignin-derived monomers.
US10253130B2
The present application provides the block copolymers and their application. The present application may provide the block copolymers that have excellent self assembling and phase separation properties and therefore that can be effectively used in various applications. The present application may also provide applications of the block copolymers.
US10253120B2
The present invention provides as steam barrier resin, a steam barrier coating agent, a steam barrier film, and a steam barrier laminate that exhibit an improved steam barrier property. The steam barrier resin is obtained by reacting a carboxylic acid group and/or an acid anhydride group of a copolymer (C) with an organometallic complex (D). The copolymer (C) is obtained by polymerizing an unsaturated hydrocarbon monomer (A) and an unsaturated carboxylic acid and/or an unsaturated dicarboxylic anhydride (B). Further, the steam barrier resin includes metal bridging between the copolymers (C). The steam barrier coating agent contains the steam barrier resin and a solvent (B). The steam barrier film of the present invention is a film containing the steam barrier. The steam barrier laminate is obtained by laminating the steam barrier film of the present invention on at least one surface of a substrate film.
US10253112B2
The invention is related to a method for producing silicone medical devices, in particular, silicone contact lenses, having consistent mechanical properties in a cost-effective manner. The invention is also related to a silicone medical device, especially a soft silicone contact lens.
US10253108B2
The present invention provides a mutated antibody of the fully humanized HER2 antibody GB235-019, wherein the amino acid sequence of the heavy chain variable region and the amino acid sequence of the light chain variable region of the mutated antibody are respectively SEQ ID NO: 10, SEQ ID NO: 2; SEQ ID NO: 11, SEQ ID NO: 2; or SEQ ID NO: 12, SEQ ID NO: 2. The mutated antibody has the ability to specifically bind to human HER2 antigen, similar to the GB235-019 antibody. They can also be used in combination with additional HER2 positive tumor therapeutic agents for treating HER2 positive tumor, weakly positive tumor or negative tumor.
US10253106B2
This invention relates to the use of monoclonal and polyclonal antibodies that specifically bind to and have the ability in the alternative to become internalized by cells expressing folate receptor alpha (FRA) and to induce an immune effector activity such as antibody-dependent cellular cytotoxicity. The antibodies are useful in specific delivery of pharmacologic agents to FRA-expressing cells as well as in eliciting an immune-effector activity particularly on tumor cells and precursors. The invention is also related to nucleotides encoding the antibodies of the invention, cells expressing the antibodies; methods of detecting cancer cells; and methods of treating cancer using the antibodies.
US10253102B2
The present invention provides antibodies and antigen-binding fragments of antibodies that bind to leptin receptor (LEPR), and methods of using the same. According to certain embodiments, the invention includes antibodies and antigen-binding fragments of antibodies that bind LEPR and activate LEPR signaling. In other embodiments, the invention includes antibodies and antigen-binding fragments of antibodies that bind to LEPR and enhance sensitization of LEPR to an antigen. In certain embodiments, the invention includes antibodies and antigen-binding fragments of antibodies that bind LEPR in the presence and absence of leptin. In certain embodiments, the invention includes antibodies and antigen-binding fragments of antibodies that induce signaling in cells expressing LEPR mutants that otherwise exhibit defective or impaired signaling in the presence of leptin. The antibodies and antigen-binding fragments of the present invention are useful for the treatment of lipodystrophies and other diseases and disorders associated with or caused by leptin deficiency or leptin resistance.
US10253095B2
Compositions comprising anti-KIR antibodies and one or more secondary anti-cancer agents or anti-viral agents and methods of using such combinations (as combination compositions or in separate administration protocols) in the treatment of cancers (e.g., lung cancer) or viral infection (e.g., HIV or HCV infection) are provided.
US10253088B2
The present invention provides a modified polypeptide which binds Factor VIII. The modified polypeptide comprises a sequence as shown in SEQ ID NO:3 in which the sequence comprises at least a modification at position 1 or 3 such that the modified polypeptide binds to Factor VIII with an off rate at least 5 fold lower than a reference polypeptide comprising an unmodified SEQ ID NO:3.
US10253083B2
Therapeutic uses of modified relaxin polypeptides for the treatment of cardiovascular disease, treatment of heart failure, and decreasing fibrotic disorders are provided. Exemplary embodiments provide for the use of relaxin polypeptides which include one or more amino acid substitutions with natural or non-naturally encoded amino acids, and/or linkage to a water-soluble polymer, such as polyethylene glycol.
US10253079B2
The present invention relates to exendin-4 derivatives and their medical use, for example in the treatment of disorders of the metabolic syndrome, including diabetes and obesity, as well as reduction of excess food intake.
US10253075B2
[Problem] To provide a polypeptide which enables stimulation of numerous T cells of different derivation, and to induce strong immunological response against numerous types of cancers.[Solution] Provided is a fused polypeptide that includes a helper epitope derived from the WT1 protein, and a killer epitope derived from the WT1 protein, wherein the polypeptide includes a total of 3 to 6 of the helper epitopes and the killer epitopes per molecule of the fused polypeptide.
US10253066B2
The present invention relates to a process for the purification of Carfilzomib of Formula I that reduces the level of an acetamide impurity of Formula II preferably below 0.10 wt %.
US10253065B2
Provided herein are methods for the production of native and reconstituted hyaluronan (HA) complexes containing pentraxin-3 (PTX3) and heavy chain 1 (HC1) of inter alpha inhibitor (IαI). Compositions containing the complexes and therapeutic methods using the complexes are provided. Combinations and kits for use in practicing the methods also are provided.
US10253052B2
The present invention relates to compounds according to Formula I or Formula II, which are potential bone imaging agents. Certain compounds labeled with 68Ga displayed excellent bone uptake and retention. The present invention also relates to pharmaceutical compositions comprising a pharmaceutical acceptable carrier and a compound of Formula I or Formula II or a pharmaceutically acceptable salt thereof.
US10253049B2
Compounds of formula (I) are inhibitors of LMP7 and can be employed, inter alia, for the treatment of an autoimmune disorder or hematological malignancies.
US10253041B2
Phenylethylamino-4H-pyrimido[4,5-d][1,3]oxazin-2-one compounds of Formula I, formulations containing those compounds, and their use as mutant isocitrate dehydrogenase 1 enzyme inhibitors.
US10253039B2
The present invention provides N-benzyl-3-sulfonamidopyrrolidines and related compounds, as well as pharmaceutical compositions and sanitizing compositions containing the same. The compounds and compositions are useful as antibiotic agents. Methods for making and using the compounds and compositions are also described.
US10253038B2
Provided are fusicoccane derivatives and methods of making fusicoccane derivatives. The methods may include contacting a tethered chromophore with light to initiate a photoinduced pericyclic reaction cascade to form a 5-8-5 carbotricycle. The 5-8-5 carbotricycle may be further functionalized.
US10253037B2
The invention relates to the field of organic chemistry and medicine, and more particularly to synthetic substances of the pyrimidine series, namely 2-chloro-5-phenyl-5H-pyrimido[5′,4′:5,6]pyrano[2,3-d]pyrimidine-4-ol derivatives, having antiviral activity. Claimed are a drug with antiviral activity against HIV infection and hepatitis B virus, containing 2-chloro-5-phenyl-5H-pyrimido[5′,4′:5,6]pyrano[2,3-d]pyrimidine-4-ol derivatives of the general formula shown, where: X is selected from the group: H, NO2, Hal, OMe; R1 is selected from the group: Cl, OH; and R2 is selected from the group: Cl, SH, OH; and a drug with antiviral activity against HIV infection, containing a 2-chloro-5-phenyl-5H-pyrimido[5′,4′:5,6]pyrano[2,3-d]pyrimidine-4-ol derivative of the general formula shown, where: X is selected from the group: H, NO2, Hal, OMe; R1 is selected from the group: Cl, OH; and R2 is selected from the group: Cl, SH, OH in combination with a reverse transcriptase inhibitor selected from Retrovir, or in combination with a protease inhibitor selected from Lopinavir, in an effective amount. The result is an effective drug with antiviral activity.
US10253028B2
The compound 3,3,3-trifluoro-N-((1,4-trans)-4-((3-((S)-2-methylmorpholino)-IH-pyrazolo[3,4-d]pyrimidin-6-yl)amino)cyclohexyl)propane-1-sulfonamide having the Formula (I) or a salt thereof, its opposite enantiomer, compositions comprising the compound and its use in the treatment or prevention of leishmaniasis, particularly visceral leishmaniasis.
US10253024B2
The present invention relates to indoline and indolenine alkaloid compounds. In particular, indoline and indolenine alkaloid compounds of the invention have antibacterial activity and/or are capable of re-sensitizing the susceptibility of methicillin-resistant S. aureus to a β-lactam antibiotic. The present invention also relates to a method for producing and using the same.
US10253019B2
Compounds having the following formula (I) and methods of their use and preparation are disclosed:
US10253016B2
The present specification provides a heterocyclic compound and an organic light emitting device comprising the same.
US10253011B1
This present invention relates to novel Lubiprostone crystals and methods for preparing the same. The preparation methods provided by the invention can effectively reduce or eliminate impurity in the obtained Lubiprostone crystals.
US10253010B2
The present invention involves a compound represented by general formula (I), a derivative thereof and a use thereof: wherein R1, R2, R3, R4, R5a, R5b, R5c and X are defined as in the description.
US10252997B2
The present invention relates to a compound which may be useful as an agent for the prophylaxis or treatment of cancer, hepatitis, hepatic fibrosis, fatty liver and the like.
US10252993B2
The present invention provides a novel crystalline form of [R—(R*,R*)]-2-(4-fluorophenyl)-β,δ-dihydroxy-5-(1-methylethyl)-3-phenyl-4-[(phenylamino)carbonyl]-1H-pyrrol-1-heptanoic acid hemi-calcium salt (atorvastatin hemi-calcium salt) of the following formula 1, which is known to be useful as a drug, a hydrate thereof and a preparation method thereof:
US10252992B2
Provided is a compound having a formyl peptide receptor like 1 (FPRL1) agonist effect.The present invention relates to a compound represented by the general formula (I) or a pharmacologically acceptable salt thereof. The present invention also relates to a pharmaceutical composition containing the compound represented by the general formula (I) or a pharmacologically acceptable salt thereof.
US10252989B2
The invention relates to picolinamides of Formula I and their use as fungicides.
US10252986B2
The present invention provides an improved process for the preparation of exametazime, which is used as ligand in preparation of technetium-99m complex.
US10252982B2
The present invention is directed to novel neuro-attentuating norketamine (NANKET) compounds according to any one of formulas (I-shown below), (I-A) and (I-B)), or any of the compounds described in Tables A-D, or in any of the Examples provided herein, and pharmaceutically acceptable salts thereof, novel pharmaceutical formulations and novel methods of uses thereof. The present invention also features novel oral neuro-attenuating ketamine (NAKET) and neuro-attenuating norketamine (NANKET) modified-release pharmaceutical formulations, and novel methods of administration thereof, which ensure the steady release of a therapeutically effective amount of ketamine, norketamine, or derivatives thereof from the oral modified-release pharmaceutical formulations without neurologically toxic spikes in plasma concentration of the ketamine, norketamine, or derivatives during the release periods.
US10252977B2
The present invention relates to halogen-substituted phenoxyphenylamidines of the general formula (I), to a process for their preparation, to the use of the amidines according to the invention for controlling unwanted microorganisms and also to an agrochemical formulation for this purpose, comprising the halogen-substituted phenoxyphenylamidines according to the invention. Furthermore, the invention relates to a method for controlling unwanted microorganisms by applying the compounds according to the invention to the microorganisms and/or their habitat.
US10252974B2
The present invention provides a technology which enables introduction of an active ingredient (e.g. nucleic acids) into various cells with a high efficiency, and compounds used therefor. The present invention provides a compound represented by the formula: [wherein, each symbol is as defined in the present description] or a salt thereof.
US10252972B2
A method of chemically extending a carbon chain of an unsaturated fatty acid for conversion into a different unsaturated fatty acid has been reported. The present invention shortens reaction steps of conventional methods, and completes a carbon chain extending reaction in a shorter time. The present invention provides a method of extending a carbon chain of an unsaturated fatty acid by two carbons, comprising steps of four stages including a short-path conversion reaction of an unsaturated fatty chain obtained from an unsaturated fatty acid into a malonic ester derivative, and heating of the malonic ester derivative to reflux in a lower fatty acid solution. The method of the present invention can complete a carbon chain extending reaction in a shorter time.
US10252971B2
To provide a novel method for producing a halogenated acrylic acid derivative.A compound represented by the formula (1): (wherein each of R1 and R2 which are independent of each other, is a hydrogen atom or a monovalent group essentially containing a carbon atom, or R1 and R2 together form a ring, R3 is a monovalent group capable of being desorbed by R3OH removal reaction, and each of R4 and R5 which are independent of each other, is a hydrogen atom or a monovalent group essentially containing a carbon atom) and having a boiling point of at most 500° C., is subjected to R3OH removal reaction in a vapor phase in the presence of a solid catalyst to obtain an ethene derivative represented by the formula (2): the ethene derivative represented by the formula (2) and a halogenated methane represented by the formula (3): CHXYZ (3) (wherein each of X, Y and Z which are independent of one another, is a halogen atom) are reacted in the presence of a basic compound and a phase transfer catalyst, to obtain a cyclopropane derivative represented by the formula (4): and the cyclopropane derivative represented by the formula (4) is reacted by heating in a liquid phase or in a vapor phase to obtain a halogenated acrylic acid ester derivative represented by the formula (5):
US10252970B2
The invention relates to a process for dehydrating aqueous 3-hydroxypropionic acid to acrylic acid in the liquid phase, wherein aqueous acrylic acid is removed continuously from the liquid phase and the aqueous 3-hydroxypropionic acid and/or the liquid phase have a high content of oligomeric 3-hydroxypropionic acid.
US10252965B2
A vinylbenzylated phenol compound represented by General Formula (1) below is provided. (In General Formula (1), Ar0 is a bifunctional phenol compound residue having one or more monocyclic or polycyclic aromatic nuclei, R1 to R5 may be the same or different and are each hydrogen or a methyl group, and p is an integer of 1 to 4.)
US10252961B2
A process is described for directly converting a high fructose feedstock to a product mixture including one or more lower polyols in which 1,2-propanediol is produced in preference to any other lower polyols, wherein a high fructose feed and a source of hydrogen are supplied to a reaction vessel and reacted in the presence of a copper-containing, supported ruthenium catalyst to provide the product mixture.
US10252960B2
The invention concerns a method for converting a feedstock selected from sugars or sugar alcohols, alone or in a mixture, into mono- or polyoxygenated compounds, wherein the feedstock is contacted with at least one heterogeneous catalyst comprising a support selected from perovskites of formula ABO3, in which A is selected from the elements Mg, Ca, Sr and Ba and B is selected from the elements Fe, Mn, Ti and Zr, and the oxides of elements selected from lanthanum, neodymium, yttrium and cerium, alone or in a mixture, which oxides can be doped with at least one element selected from alkali metals, alkaline earths and rare earths, in a reducing atmosphere, at a temperature of 100° C. to 300° C. and at a pressure of 0.1 MPa to 50 MPa.
US10252958B2
A method for producing xylenes from a heavy reformate feed includes the steps of introducing the heavy reformate feed and a hydrogen feed to a dealkylation reactor, reacting the heavy reformate feed with the hydrogen gas in the presence of the dealkylation catalyst in the dealkylation reactor to produce a dealkylation effluent, introducing the dealkylation effluent to a splitter unit, separating the dealkylation effluent into a light gas stream, a toluene stream, a benzene stream, a C9 aromatics stream, a C10+ aromatics stream, and a mixed xylene stream in the splitter unit, introducing the toluene stream, the C9 aromatics stream, and a hydrogen stream into a transalkylation reactor, reacting the toluene stream and the C9 aromatics stream in the presence of the transalkylation catalyst to produce a transalkylation effluent, introducing the transalkylation effluent to the splitter unit, and separating the transalkylation effluent in the splitter unit.
US10252954B1
The present invention is directed to propellant grains having multiple layers consisting of an outer, slow burning, layer composition and an inner, fast burning, layer with desirable progressivity burn rates. The outer, slow burning, layer comprising a first energetic material, a first plasticizer and a first binder and an inner, fast burning, layer comprising a second energetic material, and the same plasticizer as the outer layer, and a second binder. The compositions in the propellant grain provided herein provides for a burn rate energy differential between the outer, slow burning, layer and inner, fast burning, layer of at least 2.
US10252948B2
A method for manufacturing a plugged honeycomb structure, includes: a forming raw material preparation step of mixing and kneading a partition wall base material raw material at least including cordierite powder and binder with water to obtain a partition wall base material forming raw material; a forming/drying step of forming the partition wall base material forming raw material to obtain a honeycomb formed body, and drying the honeycomb formed body to obtain a honeycomb dried body; a slurry application step of applying trapping layer forming slurry including a cordierite forming raw material or alumina to a surface of a not-fired partition wall base material of the obtained honeycomb dried body; a firing step of firing the slurry-applied honeycomb dried body; and a plugging step of disposing a plugging portion at open ends of predetermined cells of the slurry-applied honeycomb dried body or of the honeycomb fired body.
US10252945B2
This invention relates to compositions and applications for a bioceramic composition that includes from about 45 to about 55% by weight of kaolinite (Al2Si2O5(OH)4); from about 5 to about 15% by weight of tourmaline; from about 3 to about 13% by weight of aluminum oxide (Al2O3); from about 11 to about 19% by weight of silicon dioxide (SiO2); and from about 3 wt % to about 13 wt % zirconium oxide (ZrO2).
US10252938B2
The present invention aims at providing a lead-free glass composition that can be soften and flowed at a firing temperature that is equal to or lower than that of conventional low melting point lead glass. Furthermore, the present invention aims at providing a lead-free glass composition having fine thermal stability and fine chemical stability in addition to that property. The lead-free glass composition according to the present invention is characterized by comprising at least Ag2O, V2O5 and TeO2 when the components are represented by oxides, wherein the total content ratio of Ag2O, V2O5 and TeO2 is 75 mass % or more. Preferably, the lead-free glass composition comprises 10 to 60 mass % of Ag2O, 5 to 65 mass % of V2O5, and 15 to 50 mass % of TeO2.
US10252937B1
A vitreous frit comprising the following by weight percentage ranges: SiO240-60 Al2O3 5-20 Na2O10-35 Li2O0-6 CaO 0-10 SrO0-5 BaO0-5 CeO20-5 TiO2 0-9.
US10252926B2
This disclosure provides methods and compositions for removing COD-causing contaminants from water, such as cosmetic product manufacturing wastewater and personal care product manufacturing wastewater. The methods involve controlling system parameters in order to hold iron as an iron(II) species. Iron(II) has increased solubility and therefore is more active against the specific contaminants present in the wastewaters.
US10252924B2
A water stream is passed between two juxtaposed similar ion exchange membranes (AEMs or CEMs), forming an ion depletion and ion enrichment zones when an electric field is applied. As cations are selectively transferred through the CEMs, for example, anions are relocated in order to achieve electro-neutrality, resulting in the concentration drop (increase) in ion depletion (enrichment) zone. Trifurcation of the output channel allows collection of concentrated, dilute and intermediate streams, with the intermediate stream serving as input to the next stage of a serialized implementation.
US10252922B2
Disclosed is an electrolysis device including: an electrolyzing tank generating electrolyzed water and hydrogen gas as by-product gas by electrolyzing raw water supplied from a raw water supply unit; and a catalyst reaction tank having therein a hydrophobic catalyst, and receiving the hydrogen gas generated from the electrolyzing tank, and removing the hydrogen gas by a catalyst reaction.
US10252920B2
Data relating to fluid dynamics is obtained using a flow field sensor that measures acceleration and angular velocity of the sensor on three axes. Ballast control allows the sensor to obtain neutral buoyancy within the fluid. The sensor is effective in opaque fluids and closed containers as data is stored in a removable memory. Froth flotation systems are among the applications for the sensor. The small size, the geometry, and the center of mass of the sensor allow it to follow the flow field in a vessel without material disruption of the flow field or weight-induced angular displacement.
US10252919B2
Powder of particles, more than 95% by number of said particles exhibiting a circularity greater than or equal to 0.85, wherein said powder contains more than 99.8% of a rare earth oxide and/or of hafnium oxide and/or of yttrium aluminum oxide, as percentage by weight relative to the oxides, and has: a median particle size D 50 of between 10 and 40 microns and a size dispersion index (D 90−D 10)/D 50 of less than 3; a percentage by number of particles having a size less than or equal to 5 μm which is less than 5%; an apparent-density dispersion index (P<50−P)/P of less than 0.2, the cumulative specific volume of the pores which have a radius of less than 1 μm being less than 10% of the apparent volume of the powder, in which the percentiles Dn of the powder are the particle sizes corresponding to the percentages, by number, of n %, on the curve of cumulative distribution of the particle size of the powder, the particle sizes being classified in increasing order, the density P<50 being the apparent density of the fraction of particles having a size less than or equal to D50, and the density P being the apparent density of the powder.
US10252909B2
The present invention relates to a method for dry reforming of at least one alkane carried out in at least one reaction chamber, preferably with a catalytic bed, having a stream of gas passing through same. According to the invention, said at least one reaction chamber comprises a catalytic solid which is cyclically and alternatively exposed to a stream of at least one alkane and a stream containing carbon dioxide, such that said catalytic solid is used as an oxidation vector.
US10252904B2
Systems and methods of custom condiment dispensing include a reservoir of base condiment and a plurality of flavoring reservoirs. A first pump is pneumatically connected to the reservoir of base condiment. The second pump is pneumatically connected to at least one flavoring reservoir of the plurality of flavoring reservoirs. A nozzle is fluidly connected to the reservoir of base condiment and fluidly connected to the plurality of flavoring reservoirs. The nozzle is configured to simultaneously dispense the base condiment and at least one flavoring therethrough. A controller receives the user selections of the base condiment and the at least one flavoring and operates the first pump and the second pump to dispense base condiment and at least one flavoring.
US10252903B2
A device for pulling a hose and nozzle assembly comprises a laterally-extending grip manually engageable by one or both hands to grip the device and pull a hose and nozzle assembly attached thereto. A lock is spaced below the grip and is releasably engageable with the hose and nozzle assembly. The lock or hose and nozzle assembly is movable relative to the other between (i) a locked position, wherein the hose and nozzle assembly is secured by the lock to the device and the hose and nozzle assembly is supported therefrom, and (ii) an unlocked position, wherein the hose and nozzle assembly is released from the lock and detached from the device. In the locked position, the laterally-extending grip is manually engageable to pull the device, including in a position behind the back, and thereby pull the hose and nozzle assembly secured thereto.
US10252896B2
The invention relates to a lifting gear having a flexible drive and a traction drive movable by the flexible drive. The flexible drive can be actuated by a lever arm arranged to pivot, and in the region of the free end of the lever arm, a handle is connected to the lever arm by an articulated joint. The handle can be pivoted from a starting position into an operating position.
US10252894B2
A self-homing hoist includes a controller configured to initiate a self-homing process to return the hook assembly to a homed position in response to each of at least one homing factor being true. Each homing factor is true or false based on a comparison of the current condition of the homing factor with a threshold requirement. If the current condition satisfies the threshold requirement, then the homing factor is true. If the current condition does not satisfy the threshold requirement, then the homing factor is false. Where all homing factors are true, the controller can initiate the self-homing process by activating a hoist motor to drive the cable drum and reel the hook assembly into the homed position.
US10252893B2
System, apparatus, device, kit, method and associated technique for safely and securely lifting wall and other structures to a vertical position. An electronic winch device that when connected to an end of a wall structure lifts the structure. A keeper or catchment such that when the electronic winch has hoisted the wall structure to a substantially vertical position, catches and keeps the wall structure in place, allowing the technician to more properly secure the wall structure. The apparatuses are also designed for portability and collapsibility, with structural members telescoping inside one another to minimize size in transport but securely configurable when extended and locked into place.
US10252891B2
An apparatus including a base, a guide arm pivotable relative to the base, the guide arm movable between a raised position and a lowered position. A tension linkage having a distal end extending away from the base, the tension linkage supported by the guide arm when the arm is in the raised position. A tension linkage guide disposed on the guide arm, the tension linkage guide movable along the tension linkage as the guide arm moves between raised and lowered positions. A lid hook connected to the distal end of the tension linkage. When the lid hook is engaged with a cargo vessel lid, the tension linkage forms a first tension angle and a second tension angle when the guide arm is in the raised position and the lowered position respectively, the second tension angle being less than the first tension angle.
US10252888B2
A drive machine for an elevator includes a motor module including at least a motor, a drive shaft, and a first transmission wheel, which are provided with a common rotational axis and connected coaxially to each other. The drive machine further includes a traction module including at least a traction wheel engageable with elevator hoisting ropes, and a second transmission wheel, which are provided with a common rotational axis and connected coaxially to each other. The motor module and the traction module are positioned side by side with their rotational axes parallel, such that the traction wheel and the drive shaft are side by side, and the first and second transmission wheels are side by side. The drive machine further includes an endless drive member passing around the first and second transmission wheels. An elevator comprising said drive machine is also disclosed.
US10252885B2
An elevator system that may be ropeless is in a structure and includes a guide rail and a guide rail extension that may generally guide a car between a hoistway and a transfer station of the system. The rail extension may generally project telescopically downward from the first rail and toward the transfer station. The telescopic relationship between the guide rail extension and the guide rail may generally compensate for vertical structure compression that may occur over a period of time.
US10252878B1
A storage system for containing at least one of a spool defining a spool passageway and at least one bobbin defining a bobbin passageway comprising first and second containers. The first container contains at least one spool and defines at least one of a first upper connecting portion and a first lower connecting portion. The second container contains at least one bobbin and defines at least one of a second upper connecting portion and a second lower connecting portion. The first upper connecting portion engages the second lower connecting portion to detachably attach the first and second containers in a first configuration. The second upper connecting portion engages the first lower connecting portion to detachably attach the first and second containers in a second configuration.
US10252873B2
An image forming apparatus includes a main body and a processing apparatus. The processing apparatus includes a first processing unit and a second processing unit. The main body has a manual-feed tray at one lateral face. The first processing unit and the second processing unit are stacked in the vertical direction on the same lateral face side of the main body as the manual-feed tray provided. The second processing unit is slidable in a toward-away direction between a connecting position and a separate position, and has a hollow to insert the manual-feed tray therein at the connecting position.
US10252872B2
A sheet conveying apparatus includes: a feeding unit configured to feed a sheet member; a conveying roller that is provided downstream of the feeding unit in a conveying direction, and that is configured to convey the sheet member fed by the feeding unit downstream in the conveying direction; a motor configured to drive the conveying roller. In a state where the conveying roller is conveying a first sheet member that was fed by the feeding unit, if a value of a torque current component of a drive current flowing in a winding of the motor changes from a value greater than or equal to a predetermined value to a value less than the predetermined value, the feeding unit starts feeding of a second sheet member that is to be fed after the first sheet member.
US10252863B2
A drive for a belt conveyor system includes a permanently excited synchronous motor having a stator and a rotor, wherein a gap size is formed between the rotor and the stator, and a holding device is provided, which is secured to the stator via a first securing device and to the rotor via a second securing device in order to provide secure assembly of the drive, such that the gap size is maintained, where the first securing device and/or the second securing device are detachably formed, such that an uninterrupted operation of the belt conveyor system is guaranteed.
US10252862B2
A system and method for a picking station operation, provides switched flexibly between single-step- and dual-step-picking into various types of order containers. The task is solved by the provision of a second order container conveyor technique for transporting second order containers, in particular boxes, for receiving articles into order container bays, arranged also in the arrangement row, of the picking station.
US10252859B2
An automated storage and retrieval system including a storage structure with storage racks having a seating surface configured to support case units where a position of each case unit is non-deterministic for each storage location on the storage racks, each case unit has a predetermined storage position and a controller is configured to determine the predetermined storage position, a picking aisle configured to provide access to the case units within the storage structure, and a seismic disturbance restorative system including seismic disturbance motions sensors disposed on the storage racks, a seismic disturbance control module in communication with the seismic disturbance sensors and configured to identify a seismic disturbance, and an automated case mapper configured to traverse the picking aisle, the automated case mapper being in communication with and initialized by the seismic disturbance control module to identify a seated position of at least one case unit within the storage structure.
US10252856B2
Various implementations of a fluid collection system having a flexible liner are disclosed. In one exemplary variation, the fluid collection system may include a container having a top opening, a lid configured to close the top opening, and a flexible liner attached to the lid. The liner may be interposed between the lid and the container when the lid closes the top opening. The liner and the lid may define a substantially sealed interior space therebetween. The lid may include an access port through which the interior space receives fluid. The flexible liner may also be configured to controllably collapse as the fluid is removed from the interior space.
US10252850B2
A redox composition includes a carbohydrate material and a catalytic molar amount of an organic compound positioned in catalytic relationship with the carbohydrate material to catalyze oxidation of the carbohydrate material in an environment in which the carbohydrate material would not otherwise oxidize.
US10252848B2
A flexible pouch having a pair of spaced apart flaps is provided. The flexible pouch includes a pouch body having a generally cylindrical shape. The flaps are disposed along the longitudinal length of the pouch body as to help prevent the pouch body from rolling over when laid on its length. The pouch may further include a fitment and an intermediate portion having a ramp shaped portion. The ramp shaped portion is opposite the fitment and slanted so as to direct fluids towards the fitment.
US10252843B2
An indexable dispenser extracts single-serving doses from a multi-serving supplements cartridge for delivery as a drinkable solution. The indexable dispenser includes a lance that punctures one serving chamber at a time so that its granulated contents can be drained into a mixing cup. The lance is attached to a rotatable flap, along with a spur. The spur punctures a membrane covering a marker zone when the flap is closed to enable machine readability. The granulated supplements are mixed with water before consumption. The indexable dispenser is configured with a dispensing window to reveal only one serving chamber at a time. The supplements cartridge is manually positioned so that an unopened serving chamber is presented in the dispensing window each time for extracting its supplements. The mixing cup may be collapsible, and together with a cap, stored in a cavity of the supplements cartridge for travel.
US10252835B2
A method for using an attachment tag with a product includes affixing an adhesive layer of the attachment tag to the product. The attachment tag includes an elastomer portion and a tag portion bonded to the elastomer portion along a bond zone, wherein the adhesive layer is disposed on the tag portion. The method also includes expanding the elastomer portion by at least partially separating at least two of a plurality of leg segments of the elastomer portion and securing the expanded elastomer portion around at least a portion of the product.
US10252833B2
The present disclosure relates to a package box and a liner for the same. The package box includes a hexahedral outer box body; a cover configured to cover an opening of the outer box body; a substantially hexahedral liner placed in the outer box body and having six side walls, at least one of which side walls is configured to be a movable side wall, each movable side wall being slidably coupled with the adjacent four side walls to change the volume of the liner; and at least one resilient member disposed between each movable side wall and the wall of the outer box body facing the movable side wall, or between each movable side wall and the cover respectively, to drive each movable side walls to move towards and to get in close contact with articles placed within the liner.
US10252827B2
A packaging system and method for receiving articles from a first location, such as a product delivery system, transporting the articles to a second location for unloading the articles such that they are placed in a desired orientation and number of columns, rows, and stacks.
US10252821B2
A processing station for registering a piece of passenger's luggage for a trip, wherein the processing station comprises: an injector for receiving the piece of luggage associated with the passenger; at least one sensor associated with the injector, the at least one sensor, in combination with at least the floor of the injector, creating a zone around the piece of luggage; and a controller associated with the sensor being adapted to: monitor, via the at least one sensor, intrusions through the zone to determine one or more of whether a predetermined limit on dimensions of the piece of luggage has been exceeded or whether a foreign object has intruded the zone from outside, and allow further processing of the piece of luggage only if no intrusion of the zone is detected; and wherein the controller adjusts the area of the zone to accommodate different sizes of luggage.
US10252816B2
An EM emitter includes at least three orthogonal coils driven by an oscillating voltage source, with the coils being electrically in parallel or series. When used in a vehicle, particularly an airplane, and the vehicle is lost, e.g., sinks, the emitter's EM signal passes through water with little attenuation and can be detected and the vehicle located.
US10252810B2
A propulsion system for an aircraft is provided having a propulsion engine configured to be mounted to the aircraft. The propulsion engine includes an electric machine defining an electric machine tip speed during operation. The propulsion system additionally includes a fan rotatable about a central axis of the electric propulsion engine with the electric machine. The fan defines a fan pressure ratio, RFP, and includes a plurality of fan blades, each fan blade defining a fan blade tip speed. The electric propulsion engine defines a ratio of the fan blade tip speed to electric machine tip speed that is within twenty percent of the equation, 1.01×RFP−0.311, such that the propulsion engine may operate at a desired efficiency.
US10252806B2
An electrothermal heater mat (3) is provided for an ice protection system for an aircraft (1) or the like. The heater mat (3) is a laminated heater mat and comprises dielectric layers (50-58), a heater element (501) and a conductive ground plane (71-74) for detecting a fault with the heater element (501). The dielectric layers (50-58) are made of thermoplastic material, and the ground plane (71-74) is formed by spraying metal such as copper onto the thermoplastic material of one of the dielectric layers.
US10252805B2
A flow duct able to be connected to a ram outlet header includes a band having an annular shape and a glove connected to the band. The glove can include a first end that is annular in shape and connected to the band, a body that is curved and has a substantially U-shaped cross section with a first opening, and a second end that has a substantially U-shaped cross section and a second opening that is an extension of the first opening.
US10252800B1
A aerial drone deployed NDE scanner test unit (12) has a yoke to which four sets of offset pins (294, 354) pivotally secure a sensor probe (232) in a configuration for rotating about the X-axis and the Y-axis with constrained rotation. Each set of the offset pins (294, 354) are spaced apart, with the ends closest to the terminal ends of the sensor probe (232) and an EUT (26) being more closely spaced than opposite ends of the offset pins (294, 354). The NDE scanner (16) is deployed from an aerial drone (14) with a cable (18) and an umbilical (20) connecting there-between. The cable (18) selectively secures the NDE scanner (16) to the aerial drone (14) and the umbilical (20) provides data and fluid connections. The NDE scanner (16) has a stand-off mechanism (118) which is selectively operated to engage and disengage the magnetic wheels (94) of the NDE scanner (16) from a metal surface of the EUT (26).
US10252796B2
An aircraft includes a wing where a first rotor and a second rotor are coupled to the wing at a fixed position relative to the wing. The aircraft also includes a fuselage and a bearing. The bearing mechanically couples the wing and the fuselage and permits the wing and the fuselage to rotate with respect to each other about an axis of rotation. The bearing permits the fuselage to rotate under the influence of gravity to be in a same orientation relative to ground when the wing is in a first orientation relative to the ground as well as a second orientation relative to the ground.
US10252776B2
A vessel with three platforms—an outer hull, an inner deck hull and a passenger carriage, having four independent suspension systems there between so as to accommodate for the multi axis movements of the outer hull. This multi axis suspension system spread between the three platforms will offer the passenger carriage stability against the pitch, yaw and roll rotations a vessel makes as it twists and turns going up and down the slope of a wave as well as the heave, sway and surge movements induced by the waves pushing the vessel around and or the ship sliding down the face of a wave.
US10252765B2
A handle attachment of the present invention is attached to a bullhorn handle of a time trial bike equipped with downhill bars, armrests and bullhorn handles. The handle attachment includes a locking part attached to the vicinity of the tip end of the bullhorn handle. Moreover, the locking part has a wall surface portion protruding outward from the surface of the bullhorn handle and forming a wall surface.
US10252755B2
Embodiments provide an aerodynamic fairing system that may comprise a base configured to mount to a vehicle, an arm coupled to the base at a proximate end and extending laterally, an a fairing mounted to the arm having an inboard and an outboard surface. The fairing outboard surface may provide an aerodynamic outer surface to direct flow to an angle to the rear. The arm may a fixed or adjustable length arm. The arm may provide a mounting area for a mud flap such that aerodynamic system may act as a mud flap hanger. Embodiments also provide an adjustable mud flap hanger.
US10252753B2
A mud flap assembly includes a mud flap with a mounting surface and an exposed surface, where the exposed surface is on an opposite side of the mud flap from the mounting surface. A foam tape is adhesively mounted to the mounting surface and a spring clip contacts the exposed surface of the mud flap when the mud flap is mounted to a vehicle so as to compress the foam tape.
US10252745B2
There are provided a motor control apparatus, an electric power steering apparatus, and a vehicle, capable of controlling the driving of an electric motor accurately even when a failure occurs in a motor electric angle detecting unit that detects a motor electric angle. The motor control apparatus includes: a relative offset amount estimating unit that estimates a relative offset amount between a reference value of an output shaft rotational angle detection value of a steering shaft, detected by an output-side rotational angle sensor, and a motor electric angle original point of a three-phase electric motor; and a motor electric angle estimating unit that calculates a motor electric angle estimate (θme) based on the output shaft rotational angle and the relative offset amount, wherein when at least either one of a resolver and an angle computing unit is abnormal, the driving of the three-phase electric motor is controlled based on the motor electric angle estimate estimated by the motor electric angle estimating unit.
US10252742B2
An electromechanical power steering system for a motor vehicle may include a driving worm that is driven by an electric motor and acts on a worm gear that is coupled to a steering shaft. The driving worm may be mounted in such a way that it can rotate about its worm axis. More particularly, the driving worm may be mounted in a bearing that is held in a mount. The mount may prestress the driving worm in a direction of the worm gear. In some examples, the mount is torsionally weak about a torsion axis that is positioned perpendicularly with respect to the worm axis.
US10252741B2
An electrostatic steering wheel hold detection device includes: a first heater element located in a steering wheel, and has one end electrically connected to a power source; an inductor—that is electrically connected to an other end of the first heater element; a second heater element that is included in the steering wheel, and has one end electrically connected to the other end of the first heater element via the inductor; and a sensor circuit that is electrically connected to a connection point between the first heater element and the inductor, and detects, from a change in capacitance at the connection point, whether or not the steering wheel is held. An other end of the second heater element is electrically connected to a ground. The second heater element is located lower than the first heater element in the steering wheel when the steering wheel is in a neutral position.
US10252737B2
A shelf for a trolley comprising a plate providing a surface for carrying goods, such as potted plants and flowers, and hooks for mounting the shelf in the trolley. One or more of the hooks are formed from a metal strip bent about an axis extending perpendicular to the central plane of the plate.
US10252735B2
A monitoring method and system monitor a transmitted current that is injected into conductive components of a route traveled by vehicle systems, monitor a received current that represents a portion of the transmitted current that is conducted through the conductive components of the route, examine changes in the transmitted and/or received current over time to determine when the vehicle systems are on the route between a first location where the transmitted current is injected into the conductive components and a second location where the received current is monitored, and examine the changes in the transmitted and/or received currents. The changes are examined to identify (a) a contaminated portion of a surface on which the route is disposed, (b) a foreign object other than the vehicle systems that is contacting the route, and/or (c) a damaged or broken portion of at least one of the conductive components of the route.
US10252732B2
A vehicle restraint system for an auto-rack railroad car which includes an active chock and an anchor chock configured to co-act to secure a vehicle in the auto-rack railroad car. In various embodiments, each chock has a chock body including a substantially diamond shaped elongated tube which includes four integrally connected elongated walls. In various embodiments, for each chock, various components of that chock extend substantially along longitudinal axis that lie in the same or substantially the same vertical plane as the apex and trough of the substantially diamond shaped elongated tube of the chock body. The active and anchor chocks: (a) have a lower height than known commercially available vehicle restraints; (b) have a smaller width than known commercially available vehicle restraints; (c) position the strap and the torque tube closer to the tire of the wheel than any known commercially available vehicle restraints; (d) take up a smaller area of each safe zone adjacent to the wheel than known commercially available vehicle restraints; (e) provide a greater strength to size ratio than known commercially available vehicle restraints; and (f) are easy to operate, install, and remove.
US10252731B2
A loading train (1) consists of at least two loading wagons (2, 3) for transporting and storing bulk material, each having a wagon frame (5) supported on on-track undercarriages (4), a storage box (6) with a bottom conveyor belt (8) which is situated in the bottom region of the storage box and extends in the longitudinal direction (7) of the wagon, and a pivotable transfer conveyor belt (9) adjoining the bottom conveyor belt (8) and projecting beyond the wagon frame (5). A tilt protection device (11) is provided between the front-most, first loading wagon (3)—with regard to a transport direction (10) of the bottom conveyor belt (8)—and the following, second loading wagon (2). The tilt protection device (11) is designed for contacting the rearward wagon frame end of the first loading wagon (3) in order to block an upward movement of the wagon frame (5).
US10252730B2
A railcar system that includes a railcar having a first longitudinal gate and a second longitudinal gate. The system further includes a first beam and a second beam configured to move longitudinally with respect to the railcar. The system further includes a driving system configured to transition the first beam from a first position to a second position. The first longitudinal gate and the second longitudinal gate are both closed when the first beam is in the first position. The first longitudinal gate is at least partially open and the second longitudinal gate are closed when the first beam is in the second position. The driving system is also configured to transition the first beam from the second position to a third. The first longitudinal gate and the second longitudinal gate are both at least partially open when the first beam is in the third position.
US10252726B2
The driving assistance device acquires, from an autonomous driving controller that determines an action of a vehicle during autonomous driving of the vehicle, action information indicating a first action that the vehicle is caused to execute. The driving assistance device acquires, from a detector that detects a surrounding situation and a travel state of the vehicle, detection information indicating a detection result. The driving assistance device determines a second action which is executable in place of the first action, based on the detection information. The driving assistance device generates a first image representing the first action and a second image representing the second action. The driving assistance device outputs the first image and the second image to a notification device such that the first image and the second image are displayed within a fixed field of view of a driver of the vehicle.
US10252721B1
A computer-implemented method and system for controlling vehicles in a vehicle convoy. The vehicles in the vehicle convoy include a following vehicle and a preceding vehicle positioned immediately ahead of the following vehicle. The method includes receiving vehicle convoy data about an environment surrounding the vehicle convoy, and detecting an intention of a remote vehicle to execute a cut-in maneuver into a path of the following vehicle. The method includes controlling a vehicle system of the following vehicle to project a status indication to a ground surface between the following vehicle and the preceding vehicle. Further, the method includes determining whether the cut-in maneuver is acceptable based on the intention of the remote vehicle and a distance between the following vehicle and the preceding vehicle, and controlling the following vehicle based on whether the cut-in maneuver is acceptable.
US10252720B2
A method for operating a motor vehicle that has at least one driving engine which is operatively connected to at least one drive wheel and is controlled as a function of an accelerator-pedal position in order to generate a drive torque, an engine drag-torque control being carried out to avoid skidding of the drive wheel when the accelerator pedal is moved in the direction of a neutral position. It is provided that a maximum permissible engine drag torque is specified to the engine drag-torque control as a function of a currently effective coefficient of friction of the road surface which is determined as a function of a present position of the motor vehicle.
US10252719B2
A control device for a continuously variable transmission includes a lock-up clutch of a torque converter which is arranged to connect and disconnect a power transmission between a power source and the driving wheel, and a control section configured to output a hydraulic pressure command value. The control section is configured to control a transmission gear ratio of the continuously variable transmission and an engagement state of the lock-up clutch in accordance with a traveling state of a vehicle. The control device includes a learning control section configured to perform a learning control of the engagement state of the lock-up clutch with respect to the hydraulic pressure command value, an oil vibration sensing section configured to sense oil vibration of a line pressure, and a learning control prohibiting section configured to prohibit the learning control when the oil vibration sensing section senses the oil vibration.
US10252717B2
The disclosure includes embodiments for modifying the acceleration of an ego vehicle based on wireless vehicle data included in a wireless message. A method includes receiving the wireless message that includes wireless vehicle data that describes one or more physical properties of a downstream vehicle. The wireless vehicle data indicates a presence of a traffic obstruction. The method includes determining a modification for an acceleration of the ego vehicle based on the wireless vehicle data and the indication of the traffic obstruction. The method includes modifying the acceleration of the ego vehicle based on wireless vehicle data compliant with the DSRC standard. The modified acceleration causes the ego vehicle to travel at a velocity consistent with a preceding vehicle and the downstream vehicle so that the ego vehicle does not collide with the preceding vehicle or the other downstream vehicle, which are in the same lane as the ego vehicle.
US10252712B2
A vehicle includes an engine and at least one controller. In response to a change in a rate of change of a driver control input to the vehicle, the at least one controller is programmed to alter conditions under which the engine will be started and stopped such that engine-on time increases due to the rate increasing and decreases due to the rate decreasing.
US10252699B2
A method for operating a passive radio-based locking apparatus of a transportation vehicle wherein the locking apparatus enables at least one access function of the transportation vehicle, wherein the passive radio-based locking apparatus includes a mobile device embodied as a radio key unit and a transceiver at the transportation vehicle, between which at least two electromagnetic radio signals are exchanged for the electromagnetic radio connection, and for the operation, one parameter of each of the radio connections of the passive radio-based locking apparatus is modified. Prior to enabling the access function, an identification feature of at least two data communication interfaces for setting up communication for the radio connections at the radio key unit and/or at the transceiver is modified and also each is set to a latest value, and the access function is enabled only in response to the relevant identification feature having the latest value.
US10252680B2
In one aspect the present disclosure relates to a cargo management system for use in a cargo area of a vehicle. The system may use a track secured to a wall of the cargo area. An articulating system is secured to the track and adjustably positionable at a plurality of positions along the track. The articulating system includes a mounting panel adapted to be secured to the track, at least a first frame section, and a first articulating hinge system for supporting the first frame section for movement on the mounting plate. The first articulating hinge system has a first actuating element normally held in a locked orientation to hold the first frame section stationary, and movable into an unlocked position by a rotational force applied by a user, to enable the first articulating hinge system to be rotated on the mounting plate into a new orientation, and then held in the new orientation when the first actuating element is released by the user.
US10252677B2
A footwear and accessory retention pouch serves to segregate and retain footwear and accessories in an organized, accessible manner in a vehicle. The pouch is specially adapted for suspension between the seatbacks of a vehicle having individual or split seats. The pouch comprises a container defined by container sidewalls that form an opening at one end, and at least one interior barrier that segregates the container into chambers that receive footwear. A depressed cap covers the opening in the container. The depressed cap comprises cap sidewalls and a cap platform for retaining an accessory while the cap is covering the opening in container. A rechargeable recharging device operatively connects to the depressed cap for charging a communication device. A plurality of straps and a central adjustable cable are length adjustable and extend from the sidewalls of the container for fastening container between, behind, or in front of the vehicle seats.
US10252676B2
A storage bag for use with a tonneau cover is provided. The storage bag has a main body having at least one pocket, and at least one first fastener secured to the main body for releaseably fastening the main body to a bottom surface of a tonneau cover.
US10252667B2
A vehicle trim assembly (2), comprising: a storage compartment (6) defining a storage space (8) emerging through an opening (26); and a shutter (10) moving relative to the storage compartment between a closing position, in which it closes off the opening, and an open position, in which it is freed from the opening. The shutter (10) comprises at least one transmission zone (50) able to be steered between a viewing configuration, in which the transmission zone allows the visible light to pass through the shutter and makes it possible to distinguish the contents of the storage space through the shutter, and a concealing position, in which the transmission zone does not make it possible to distinguish the contents of the storage space through the shutter.
US10252666B2
A vehicle lighting system includes a laser lighting device configured to provide a light source for a vehicle lighting device of the vehicle, and an indicator having a laser light icon. An indicator light source is configured to illuminate the laser light icon based on an operating state of the laser lighting device.
US10252651B2
Seat assemblies having seat heater wire harnesses connected to child restraint brackets for vehicles
A seat assembly includes a seatback, a seatback heater, a child restraint bracket, and a wire harness. The seatback is moveable between a seated position and a folded position. The seatback heater is connected to the seatback. The child restraint bracket includes a pair of isofix anchors. The wire harness includes a first end and an opposite second end. The first end is connected to the child restraint bracket. The second end is connected to the seatback heater. The wire harness accommodates movement of the seatback between the seated position and the folded position.
US10252650B2
A thermal comfort system for use with a vehicle seat includes an airflow management system and a thermal-electric device (TED) system. The TED system operates to conduct thermal energy between the seat occupant and the vehicle seat to enhance the thermal comfort of the seat occupant. The airflow management system operates to route a stream of conditioned air along the body of the seat occupant via cooperating air intake and air discharge ports to further enhance the comfort of the seat occupant. The conditioned air may also be routed along the TED system to enhance TED performance. The HVAC system of the vehicle can provide the conditioned air and/or a non-ambient pressure source that induces air flow along one or more portions of the thermal comfort system.
US10252639B2
Provided are an external power supply apparatus and a vehicle power supply method, whereby a power reception circuit of an electric vehicle can be projected or a configuration of the electric vehicle can be simplified. An external power supply apparatus is provided with: a power supply unit, which is provided along a traveling path, and which supplies power to a power reception unit of an electric vehicle while the vehicle is traveling; and a voltage applying unit that applies a voltage to the power supply unit. The power supply unit includes a plurality of divided power supply units that are divided along the traveling path. The voltage applying unit applies the voltage such that the voltage to be applied to the divided power supply units becomes higher in the traveling direction of the electric vehicle.
US10252634B2
A power supply apparatus and method for providing electric energy to a target system are provided. The power supply apparatus includes: a capacitor module configured to store electric charge and provide electric energy to a target system based on the stored electric charge; an internal battery module configured to be operably connected with the capacitor module in series; and an output interface configured to couple the internal battery module with the capacitor module. The internal battery module and the capacitor module provide electric energy to the target system in controllable series connection through the output interface.
US10252628B2
An electric control system for an electric vehicle operable in a plurality of modes. The control system includes an electric motor having a plurality of motor coils, an energy storage device providing energy to the electric control system, transistor modules selectively coupling the electric motor to the energy storage device, a connector selectively coupling to an AC power source, a controllable switching device configured to selectively couple the connector to the electric motor; and a microcontroller controlling the switching device to couple the connector to at least one of the motor coils during a detected charging mode, and control one or more of the plurality of transistor modules to couple the motor coil to the energy storage device during the detected charging mode.
US10252604B2
According to an attaching structure of a roof side weather strip, a retainer includes a vehicle upper side wall, a connecting part, and an inboard side wall. A first tip locking part, formed in a tip of the vehicle upper side wall, is engaged in a tip locking groove, formed in a tip of a vehicle upper side wall of the weather strip. The vehicle upper side wall of the weather strip is held by the vehicle upper side wall of the retainer. The inboard side wall of the retainer is allowed to abut on an inboard side wall of the weather strip, and a tip of a second tip locking part formed by bending the tip obliquely in the inboard direction is engaged in the engaging groove, so that the inboard side wall of the weather strip is held by the inboard side wall of the retainer.
US10252600B2
There is disclosed an air-conditioning apparatus for vehicle which is capable of selecting an appropriate operation mode while inhibiting the operation mode from being unnecessarily changed, and achieving rapid and stable vehicle interior air conditioning. A controller has respective operation modes of a heating mode, a dehumidifying and heating mode, a dehumidifying and cooling mode, and a cooling mode, and selects and executes these operation modes. The controller has a dehumidifying and heating mode maximum radiator temperature MAP and a dehumidifying and cooling mode maximum radiator temperature MAP. The controller selects an operation mode in which a radiator target temperature TCO is achievable by heat radiation in a radiator 4 with reference to each MAP, on startup or at a time of change of the operation mode.
US10252596B2
Vehicle climate control system and method for control of the vehicle climate control system for temperature regulation of a vehicle battery, the vehicle climate control system includes a refrigerant circuit containing at least a compressor, a gas cooler/condenser, an expansion element, an evaporator, as well as refrigerant lines to connect the components, wherein an intermediate expansion element is arranged upstream from the expansion element in the refrigerant flow direction and a heat exchanger for the temperature regulation of a vehicle battery is arranged between the expansion elements.
US10252585B1
A self-inflation device for maintaining pressure in a tire, the self-inflation device includes a body having a piston compartment and an intake opening external to an inner space of the tire and a piston housed in the piston compartment and having a piston opening internal to the inner space. The piston is moved to a pulled position by centrifugal force applied by rotation of the tire to open the intake opening, and moved to a pushed position by air pressure from the inner space to block the intake opening and create a compression chamber within the piston compartment. The self-inflation device further includes a valve separating the compression chamber and the piston opening. The valve is opened when the piston is in the pushed position to allow airflow between the compression chamber and the inner space.
US10252575B2
A pneumatic tire includes a first projection formed on a buttress portion, and projecting toward the outside in a tire width direction. The first projection includes a projection body projecting outwardly in the tire width direction from the buttress portion, a first side portion adjacent to the projection body in a tire circumferential direction, and a second side portion adjacent to the first side portion in the tire circumferential direction. The projection body has a main surface extending along the surface of the buttress portion. The first side portion has a first stepped surface positioned away from the main surface toward the inside in the tire width direction by a first distance. The second side portion has a second stepped surface positioned away from the main surface toward the inside in the tire width direction by a second distance which differs from the first distance.
US10252573B2
A tire, wherein, in a cross section in the tire width direction thereof in a state where the tire has substantially not been inflated with no load applied thereon, provided that the maximum height in the tire radial direction of the carcass is h, a radius of curvature of the carcass within a height range 0.91 h-h measured from the radially innermost position of the carcass is R7, an acute inclination angle specifically defined in the height range 0.91 h-h is θ7, the intermediate value of a radius of curvature in the height range 0.82 h-0.91 h is R6, a radius of curvature in the height range 0.63 h-0.82 h is R5, and an acute inclination angle specifically defined in the height range 0.63 h-0.82 h is θ5, R7≥0.26h, θ7≥14°, R6
US10252572B2
An airless tire includes a tread ring, a hub positioned on radially inner side of the ring, and a spoke structure including polymer material and connecting the ring and hub, the structure including spoke pieces arrayed in circumferential direction. Each spoke piece has a tread connecting portion, a hub connecting portion, and a spoke curved portion between the tread and hub connecting portions, each spoke piece has straight radial length LSb of at least 1.05 times straight radial length LSa and curved radial length LLb of at least 1.03 times LSb when positioned at 0° on coordinate around the tire axis where a perpendicular line extending vertically upward from the tire axis is set 0°, LSb is measured along the base line under base-load condition, LSa is measured along the base line under no-load condition, and LLb is measured along a curve of each spoke piece under the base-load condition.
US10252564B2
Provided is a paper clip. The paper clip includes: a paper fixing part having a base plate and a clip coupled to the base plate to fix sheets of paper to the base plate; and a fixture for fixing the paper fixing part thereto in such a manner as to allow the base plate to be separably disposed therefrom. The base plate has locking protrusions formed protrudingly from both end portions of one side thereof, and the fixture has locking hooks adapted to separably support the locking protrusions thereagainst. The base plate has a fixing protrusion formed on the region where the locking protrusions are formed, and the fixture has a fixing groove formed on a position corresponding to the fixing protrusion in such a manner as to fixedly insert the fixing protrusion thereinto.
US10252559B2
An assembly for realizing in continuous covering jackets of book elements of different dimensions starting from a film wrapped up in a coil. The assembly includes a mechanism for cutting the film unrolling from the coil for realizing pieces of the film; a first folding device of a first end of the pieces; a second folding device of a second end of the pieces; a control and command unit and a longitudinal welder suitable for both superiorly and inferiorly closing folded pockets and for regulating the height of the cover itself by trimming the parts in excess.
US10252554B2
Apparatuses, methods, and computer program products are described herein. An example disclosed printing device includes a printer body; a cradle engagement surface configured to interface with a cradle, the cradle engagement surface defining a first recess and a second recess disposed proximate a first side of a battery compartment; and a bumper attachment extending from the printer body and disposed proximate a front side of the printer body, the bumper attachment defining at least two capture cavities structured to slideably receive reciprocally structured first and second printer capture flanges extending from the cradle.
US10252534B2
A recording head recovery system has a recording head, a tank, and a control portion. The control portion can perform a recovery operation of the recording head including a cleaning solution feeding operation where cleaning solution is fed through cleaning solution feed ports by locating the tank such that the solution surface of the cleaning solution in the tank is above a first position which is the height of the cleaning solution feed ports, a wiping operation where a wiper wipes an ink ejection surface, and a non-feeding operation where the cleaning solution is sucked into the cleaning solution feed ports by locating the tank such that the solution surface of the cleaning solution in the tank is below the first position.
US10252504B2
A method for producing a smooth coating on a substrate includes applying a release coating to a first side of a film, applying an application layer to said first side of said film over said release coating, bonding said first side of said film to a first substrate, applying a printable coating to a second side of said film while said first side of said film is bonded to said first substrate, and removing said film from said first substrate leaving said application layer deposited on said first substrate and said printable coating on said second side of said film.
US10252501B2
A polyvinyl chloride (PVC) flooring, includes a wear-resistant layer, a decorative layer and a substrate layer from top to bottom in order, wherein the substrate layer comprises a flexible layer, a strength layer and a correction layer from top to bottom in order and the hardness of the strength layer is 1.05-1.10 times that of the flexible layer and the correction layer.
US10252500B2
Multilayered interlayers comprising stiff skin or outer layers and a soft core layer(s) are disclosed. The multilayered interlayers comprise: a first polymer layer (skin layer) comprising plasticized poly(vinyl butyral) resin; a second polymer layer (core layer) comprising a blend of two (or more) plasticized poly(vinyl butyral) resins having different residual hydroxyl content; and optionally a third polymer layer (skin layer) comprising plasticized poly(vinyl butyral) resin.
US10252499B2
A process includes forming a transfer film without a release layer in which the transfer film includes a substrate layer to be peeled off during a transfer process, and a transfer layer to be transferred to an article to be decorated. The transfer layer has a protective layer, a printed or vapor-deposited decorative layer, and an adhering layer, which are laminated in this order. The substrate layer is a base film of a synthetic resin formed by extruding a molten synthetic resin. The substrate layer is so laminated and thermally compressed in direct contact with the protective layer such that the substrate layer does not peel off the protective layer before the transfer process and peels off the protective layer from a peeled end portion of the substrate layer as a trigger during the transfer process, by thermally pressing the substrate layer and the protective layer between rolls.
US10252495B2
There is provided an interlayer film for laminated glass with which a low yellow index value, low excitation purity and high heat shielding properties can be achieved in spite of the thickness varying with places. The interlayer film for laminated glass according to the present invention has a thickness of one end thinner than a thickness of the other end at the opposite side of the one end and includes a thermoplastic resin, an ultraviolet ray screening agent and tungsten oxide particles, and the ultraviolet ray screening agent is a benzotriazole-based ultraviolet ray screening agent.
US10252484B2
A dunnage conversion system includes a machine for converting a stock material (14) into a strip of relatively lower-density dunnage, a coiling mechanism (20) for winding the strip into a coil, a taping mechanism (22) for automatically securing a trailing end of the strip to the coil, and a coil ejecting mechanism (24) for automatically removing the coil from the coiling mechanism. The taping mechanism includes a guide surface (70) between an outlet of the machine and the coiling mechanism to guide the strip to the coiling mechanism and to guide tape for engagement with a trailing end of the strip and to secure the trailing end of the strip to the coil. The coil ejecting mechanism includes a lever arm (126) that pivots to push the completed coil off the coiling mechanism.
US10252480B2
A method and apparatus for making reflective surfaces within optically transmissive materials. The method includes steps of providing a blade having a sharp cutting edge, penetrating an optically transmissive material with the cutting edge to a predetermined penetration depth and moving the blade relative to the transmissive material to produce a continuous slit with reflective walls. The apparatus includes a material feeding mechanism configured to feed a flexible sheet in predefined stepped increments, a slitting blade with a surface portion having a root mean square surface profile roughness parameter below 100 nanometers, and a linear drive operatively associated with the slitting blade to reciprocally move the slitting blade perpendicular to a feed direction of the flexible sheet, where a stepped feed operation of the material feeding mechanism is alternating with a reciprocal operation of the linear drive.
US10252470B2
An automated edge band application machine has a board drive assembly and an opposed caster wheel that together capture and move a work piece edge into engagement with a rotating roller banding guide with edge banding captured between. An adhesive affixes the edge banding to the work piece responsive thereto. An edging detector is located along the path of the work piece edge, in a position in advance of the board drive assembly, and is configured to detect a presence of edge band on the edge of the work piece. When the edging detector detects edging, or at a precise distance along the edge band thereafter, a cutting die assembly severs the edge band. The board drive assembly automatically adjusts to varying thickness work pieces, engages with a work piece major surface, and rotates in synchrony with a drive spindle assembly and the rotating roller banding guide.
US10252469B2
A method is provided for producing a component connection. The method includes the following steps: providing a first component, providing a first ball, pressing the first ball against the first component by a sonotrode, vibrating the first ball by the sonotrode such that material of the first ball and/or material of the first component melts, and the first ball is welded to the first component, providing a second ball, pressing the second ball against the first ball by the same sonotrode or another sonotrode, and vibrating the second ball by the same sonotrode or the other sonotrode such that material of the second ball and/or material of the first ball melts, and the second ball is welded to the first ball.
US10252464B2
A slicing printing method for color 3D model is disclosed. The method comprises following steps of: building a color 3D object into a coloring model; dividing the coloring model into a plurality of color cells, wherein a shell of each of the color cells forms an accommodating space configured to accommodate a color material; setting respectively the color of the color material accommodated by each color cell according to the color of the color 3D object and generating a printing color data corresponding to the color 3D model; generating a printing object data associated with the printing color data according to the color cells. The disclosed example can effectively realize the printing of the color 3D model through the inkjet manner via generating color cells configured to accommodate color materials.
US10252448B2
Provided are methods for heat curing of various materials, such as heat curable materials or more specifically potting compounds, which are disposed within cavities with limited access to these materials. Also provided are curing for executing such methods. In some embodiments, a heat curable material disposed within a cavity may be heated by a heating rod protruding into the cavity or through the cavity. The heating rod is thermally coupled to the heat curable material and is used to transfer heat to the heat curable material. For example, the heating rod may include a resistive heating element. The heating element may be positioned in such a way that the heat curable material is selectively heated within the cavity without significant heating of surrounding components. In some embodiments, the heating rod may be also used to compress the part containing the cavity or a stack including this part.
US10252442B2
A manufacturing method includes: a dry mixing step of dry mixing a raw material by batch processing; a wet mixing step of adding liquid to a dry mixture obtained at the dry mixing step, the liquid including at least one type of water, surfactant, lubricant and plasticizer, while wet mixing; a kneading step of kneading a wet mixture obtained at the wet mixing step; and a forming step of extruding a kneaded mixture (forming raw material) obtained at the kneading step to make a ceramic formed body. In the kneading step, the liquid is further added during kneading of the wet mixture.
US10252428B2
A utility knife includes a blade holder slidably connected to the handle. A blade lock pivotally connects to the blade holder for movement relative to the blade holder about a blade lock axis between a locked position and a released position. The blade lock axis forms an acute angle α with a lateral direction of the knife so that a surface of the blade lock that is configured to engage the utility blade moves both laterally and vertically as the blade lock moves between its locked and released positions. A blade release trigger is conveniently disposed well rearwardly of a front of the handle. The knife includes a sealed blade storage compartment with a manually openable cover. A seal disposed between the compartment and cover discourages water and/or debris from getting into the compartment when the cover is closed.
US10252426B2
A handling module for handling vehicle wheels in an installation for the surface treatment thereof and having at least two gripping units which are supported by a frame structure and each of which comprises a plurality of press-on elements which are pressable onto one or more counter surfaces of an individual vehicle wheel. At least one of the gripping units includes a translation device by which the press-on elements are movable in relation to the frame structure with a movement component which is parallel to the axis of rotation of a gripped vehicle wheel.
US10252415B2
A human-collaborative robot system includes a first force detection section that detects external force acting on a robot; a second force detection section that detects only an operating force acting on the robot when a human manually operates the robot; and a safety assurance operation command section that, in the case where the external force detected by the first force detection section exceeds a predetermined threshold value, commands a safety assurance operation of causing the robot to move in a direction that reduces the external force or causing the robot to stop. When the human is manually operating the robot while the robot is in the stopped state, the safety assurance operation command section compares a value obtained by subtracting the operating force detected by the second force detection section from the external force detected by the first force detection section with a predetermined threshold value.
US10252411B2
A tool rack includes a main body and a magnetic assembly. The main body includes a first face, at least one first clamping portion disposed at an end of the first face, and a receiving space disposed at another end of the first face and forming an opening. The magnetic assembly includes at least one magnetic member arranged in the receiving space of the main body. A portion of a tool can be clamped by the first clamping portion, and another portion of the tool can be attached to the magnetic member via a magnetic force to prevent the tool from being detached from the tool rack due to vibration or swaying.
US10252408B2
A staple removal device for removing a staple and wire arrangement from a fence post includes a main body having a first jaw and a second jaw spaced apart from each other. The first jaw and second jaw provide a first and second elongate channel respectively for receiving the wire. Both the first and second elongate channels comprise a closed end in which the wire may be received. A gripping portion is moveably connected to the main body and a lever causes movement of the gripping portion. Beneficially, a first and second block portion is configured at a surface of the main body wherein a side edge of the first and second block portion is substantially in alignment with the closed end of the first and second channel respectively so as to, in use, increase the surface area of the contact region between the staple removal device and the wire.
US10252401B2
A clamping and spreading device for separating layers of a substrate includes a C-clamp that is configured to fixedly couple to a substrate. A second rod is coupled to and extends from the C-clamp. The second rod is selectively extensible from the C-clamp. A first wedge is coupled to and extends bidirectionally from the second rod distal from the C-clamp. A second wedge is coupled to and extends from the C-clamp. An actuator is coupled to the C-clamp and is operationally coupled to the second rod. The first wedge and the second wedge are configured to insert into a first gap defined by two layers of the substrate. The actuator is positioned to compel the second rod to extend from the C-clamp. The first wedge is compelled distally from the second wedge to separate the two layers of the substrate.
US10252396B2
The present disclosure relates to polishing pads which include a polishing layer, wherein the polishing layer includes a working surface and a second surface opposite the working surface. The working surface includes at least one of a plurality of precisely shaped pores and a plurality of precisely shaped asperities. The present disclosure further relates to a polishing system, the polishing system includes the preceding polishing pad and a polishing solution. The present disclosure relates to a method of polishing a substrate, the method of polishing including: providing a polishing pad according to any one of the previous polishing pads; providing a substrate, contacting the working surface of the polishing pad with the substrate surface, moving the polishing pad and the substrate relative to one another while maintaining contact between the working surface of the polishing pad and the substrate surface, wherein polishing is conducted in the presence of a polishing solution.
US10252389B2
A clamping unit includes a drawbar having an interior surface defining a fluid transport channel. A fluid transport pipe is at least partially disposed within the interior of the drawbar and is in fluid communication with a fluid transport adapter and a fluid transport channel to enable high pressure fluid to be provided directly to a toolholder. The clamping unit further comprises at least one spring-like member positioned around the outer surface of the drawbar to provide a biasing force against an end plate. The drawbar is movable along a longitudinal axis between a locked position and a tool release position by applying and not applying hydraulic pressure against the end plate, thereby providing a quick-change feature of the invention.
US10252385B2
A tool changer is composed of a support shaft, a forward/backward movement drive motor moving the support shaft upward and downward, a rotation drive motor rotating the support shaft about an axis, a tool change arm having tool grippers formed at both ends thereof, and an air blow mechanism discharging compressed air to a tool and a next tool gripped by the tool grippers. In tool change using this tool changer, in a positioning operation, the tool change arm is rotated by degrees and compressed air is discharged toward the tool and the next tool by the air blow mechanism.
US10252380B2
A method of remanufacturing a turbine component includes electrical discharge machining a puck via the turbine component to form an electrical discharged machined puck; and brazing the electrical discharged machined puck to the turbine component.
US10252375B2
A laser processing system including a laser processing unit, a controller controlling the processing unit according to a laser processing program, and a restart preparation apparatus performing a preparation process of the controller to resume the program execution after being suspended. The restart preparation apparatus includes an operating state judging section judging whether an operating state of the processing unit when suspending the program execution is in course of laser processing, and a restart condition specifying section specifying a restart condition of the processing unit when resuming the program execution, from among predetermined conditions, based on a judgment result. The operating state judging section judges that the operating state is in course of laser processing, if a predetermined operation command for processing the workpiece is output from the controller, or predetermined external information for processing the workpiece is input to the controller, at the instant of suspending the program execution.
US10252364B2
A soldering apparatus which can keep an interior of a chamber at a specified vacuum pressure and can perform soldering in the chamber, the vacuum pressure of which is optimally adjusted, is provided with a chamber (40) in which a work (1) is solderable under vacuum environment, an operation part (21) that inputs and sets vacuum pressure in the chamber (40), a pump (23) that performs vacuum drawing on the interior of the chamber (40), a pressure sensor (24) that detects pressure in the chamber (40), and a control portion (61) that adjusts the set vacuum pressure in the chamber (40) based on a pressure detection signal (S24) output from the pressure sensor (24), and keeps the set vacuum pressure for a predetermined period of time, as shown in FIG. 4.
US10252363B2
Forming a solder joint between metal layers by preparing a structure having solder material placed between two metal layers and heating the structure to grow an intermetallic compound in a space between the two metal layers. Growing the intermetallic compound includes setting a first surface, in contact with the solder material between the two metal layers, to a first temperature, thereby enabling growth of the intermetallic compound; setting a second surface, in contact with the solder material between the two metal layers, to a second temperature, wherein the second temperature is higher than the first temperature; and maintaining a temperature gradient (temperature/unit thickness) between the two metal layers at a predetermined value or higher until the intermetallic compound substantially fills the space between the two metal layers.
US10252362B2
A method for machining a gearwheel by means of stock removal using a numerical-control machine tool with at least five machining axes. Also described are an apparatus for producing commands and a machining system which comprises a machine tool with at least five axes, data input means and calculation and processing and command units.
US10252360B2
Methods for machining may include: (a) providing a bevel gear on a workpiece spindle of a machine, the gear having a tooth having a head, (b) rotationally driving the gear about an axis of the spindle, (c) providing a first machining tool on a tool spindle of the machine, (d) machining the gear by means of the first machining tool, (e) providing a grinding tool as a second machining tool on the tool spindle or on a further spindle, (f) driving the grinding tool to rotate about a tool axis of the tool spindle, wherein the grinding tool comprises a concave machining region that has a ring shape and is arranged concentrically in relation to the tool axis, and (g) advancing the grinding tool in relation to the gear to bring the machining region into chip-removing operational connection with an edge in a region of the head to produce a chamfer on the edge by grinding.
US10252347B2
A self-locking drill chuck includes rotating sleeve provided with a convex leaf spring fixed on a rotating sleeve on both ends, its nut or the ring fixedly connected with the nut provided with a first groove and a second groove matching with the convex portion of the convex leaf spring, and the self-locking structure including a ring tooth on the drill body and a rotatable locking block disposed on the nut or ring fixedly connected to the nut. The nut or ring fixedly connected to the nut is also provided with a leaf spring, and the rotating sleeve is provided with a first part compressing the leaf spring and a second part compressing the locking block. The self-locking drill chuck can achieve positioning fit of metals, and self-locking and unlocking switching is realized by the lever without the interference phenomenon in the self-locking structure.
US10252335B2
The present disclosure provides three-dimensional (3D) printing methods, apparatuses, and systems using, inter alia, a controller that regulates formation of at least one 3D object (e.g., in real time during the 3D printing); and a non-transitory computer-readable medium facilitating the same. For example, a controller that regulates a deformation of at least a portion of the 3D object. The control may be in situ control. The control may be real-time control during the 3D printing process. For example, the control may be during a physical-attribute pulse. The present disclosure provides various methods, apparatuses, systems and software for estimating the fundamental length scale of a melt pool, and for various tools that increase the accuracy of the 3D printing.
US10252326B2
A method to manufacture reticulated metal foam via a dual investment solid mold, includes pre-investment of a precursor with a diluted pre-investment ceramic plaster then investing the encapsulated precursor with a ceramic plaster.
US10252315B2
A metal punch assembly for use with a ridged metal sheet includes a base member that defines a plurality of grooves. A plurality of punches are movably connected to the base member and are translatable from a retracted position to an extended position. The grooves formed by the base member are engageable with the ridges on the sheet such that the motion of the apparatus is limited to translation in two opposite directions.
US10252312B2
A manufacturing method for a pressed component of the present disclosure is a manufacturing method for a pressed component configured including an elongated top plate, ridge line portions at both short direction ends of the top plate, and vertical walls that face each other in a state extending from the ridge line portions. A punch and a die are employed to curve a blank into a convex profile bowing from the punch side toward the die side in a state in which the punch is caused to contact a first portion of the blank where the two end ridge line portions are to be formed, and to sandwich a second portion of the blank where the top plate is to be formed between the die and the punch and indent the second portion from the die side toward the punch side.
US10252308B2
A paintless dent removal tool having a handle with a side and two opposing ends. The tool having a substantially rigid stem with a proximal segment and a distal segment opposite the proximal segment, and configured with the proximal segment extending from the side of the handle between the two opposing ends. The stem comprises an elongated curve between the proximal segment and the distal segment of the stem, and a substantially rigid tip extends in an angular fashion from the distal segment of the stem.
US10252307B2
Each time a highly-viscous substance is extruded, a variation in weight of each cut piece of the highly-viscous substance is minimized. Metallic sodium (5) loaded in an extruder main body (3) is extruded from a nozzle (7) of the extruder main body (3) with a pressing tool (4) and, when it is detected that the metallic sodium (5) is extruded to a predetermined position, the movement of the pressing tool (4) is stopped and the extruded metallic sodium (5) is cut. In this case, an impulse (P) after stop is brought closer to a constant value until a load no longer acts on the metallic sodium (5) in the extruder main body (3) after stopping the movement of the pressing tool (4) by adjusting the movement speed of the pressing tool (4).
US10252306B2
Methods and Apparatus to increase the efficiency of roll-forming and leveling systems are described herein. An example strip material processing apparatus includes a first drive system to drive an exit workroll at an exit of the strip material processing apparatus, and a second drive system to drive an entry workroll at an entry of the strip material processing apparatus, where the strip material is to travel through the strip material processing apparatus from the entry to the exit. The example strip material processing apparatus also includes a controller to provide a first command reference to the first drive system to drive the exit workroll at the first command reference. The controller is to determine a first torque value of the first drive system when the first drive system operates at the first command reference, and the controller is to determine a second torque value based on a ratio of the first torque value to the second torque value such that the first torque value and the second torque value are different. The controller is to also drive the entry workroll via the second drive system to maintain the ratio.
US10252304B2
A method of remediating an environmental contaminant and device for performing the same is disclosed herein. The device uses a liquid carrier source with a venturi pump in liquid communication with the liquid carrier source and an output for the venturi pump and at least one injection port in fluid communication with the output of the venturi pump. The injection port injects a remediator, such as an oxidizing material or chemical, into the liquid carrier, which is then contacted with the environmental contaminant and permitted to degrade or dispose of the environmental contaminant.
US10252298B2
A classifying wheel for a centrifugal-force air classifier where the flow pattern of the classifying air is contrary to its centrifugal direction, namely centripetal, and which is equipped with extensions fitted to the classifying wheel vanes within the flow channels which influence the flow pattern is to be executed in wear-protected design. This is achieved in that the classifying wheel has at least one reinforcing ring which has uniformly spaced hooks arranged around its periphery which fix the classifying wheel vanes to the extensions so that the outside radial edge of the classifying wheel vanes is not in contact with the reinforcing ring.
US10252293B2
A method for coating a surface of a closed cooling channel, having a plurality of oil supply bores and a plurality of oil discharge bores, of a piston for an internal combustion engine, having a coating medium containing hexagonal boron nitride may include introducing a defined quantity of a coating medium comprising a suspension of hexagonal boron nitride with a solution on a basis of at least one thermally curable inorganic binder and at least one solvent into the cooling channel, spreading the coating medium over the surface of the cooling channel by moving the piston about at least two spatial axes, using a laminar air flow to dry the coating medium spread over the surface of the cooling channel, and thermally curing the coating medium to complete a coating adhering to the surface of the cooling channel.
US10252284B2
An actuator for a hand operated foam dispensing pump that utilizes a folding nozzle is presented. The folding nozzle of the actuator is configured so as to lock the actuator in place and prevent operation of the pump when the nozzle is folded. The actuator substantially reduces pump closure loosening (back-off) and nozzle breakage during shipping of a filled product by eliminating trigger handles or other conventional nozzle types which protrude from the side of the actuator. As such, the new actuator is particularly well-suited for use in e-commerce where the shipping of unboxed products is becoming increasingly common. The actuator is configured such that actuator depression (actuation) cannot occur when the folding nozzle is in a folded position.
US10252281B2
The present application belongs to fluid control equipment, in particular, relates to directional controlling mechanism of fluidic sprinkler, comprising a rear reversing mechanism, a front reversing mechanism and a signal stream switching mechanism. A limiting shift rod of the rear mechanism rotate around a locating rod as the center after touching a limiting ring, then realize the reversing of the limiting shift rod. The reverse action of the limiting rod will finally lead a reversing arm to rotate by way of driving a reversing locating block, a rear reversing rod and a front reversing rod to rotate. The rear reversing mechanism, the front reversing mechanism and the signal stream switching mechanism act together, so as to switch a left-side signal stream nozzle and a right-side stream nozzle of a fluidic sprinkler, and bring about the reversing of the rotation direction of the fluidic sprinkler. Directional controlling mechanism of fluidic sprinkler is in a stepping state respectively in the clockwise and the counter clockwise working modes, so that the impact force on a rotary body is small, critical components tend to have a longer working life, an intermediate position does not exist during the reversing of the sprinkler, and the switching of the sprinkler is stable and reliable.
US10252274B2
The present invention relates generally to wood chippers and baling machines and methods of operation therefor, and more specifically, to an apparatus and a method for chipping tree branches and the like and baling wood chips formed from such chipping activities. The apparatus includes a chipper assembly having a chipping mechanism operable to reduce the trimmed branches to wood chips. Also provided is a bale forming assembly operatively connected to the chipper assembly. The bale forming assembly has a housing and a baling mechanism contained within an interior space of the housing. The housing has an opening defined therein for receiving wood chips from the chipper assembly. The opening provides access to the interior space of the housing. The baling mechanism is operable to form a bale from the wood chips produced by the chipper assembly.
US10252273B2
A valve for dispensing a fluid comprising a dry portion and a wet portion is presented. Only the wet portion is contacted by the fluid. The wet portion comprises a fluid dispenser unit having a inlet opening, a capillary nozzle providing a fluid outlet, a cavity, the capillary nozzle having an end within the cavity, and a plunger. The plunger moves within the cavity into an opening position allowing an inflow of the fluid through the inlet opening through the cavity and an outflow of the fluid through the capillary nozzle. The plunger has a sealing surface directed towards the end of the capillary nozzle. The plunger moves into a closing position for sealing the end of the capillary nozzle with the sealing surface. The dry portion comprises a closing component for exercising a magnetic closing force onto the plunger for attracting the plunger into the closing position.
US10252266B2
In some aspects, the present disclose provides methods for amplifying and quantifying nucleic acids. Methods for amplifying and quantifying nucleic acids comprise isolating a sample comprising nucleic acid molecules into a plurality of microchambers, performing a polymerase chain reaction on the plurality of microchambers, and analyzing the results of the polymerase chain reaction. In some aspects, the present disclosure provides devices consistent with the methods herein.
US10252263B2
Microfluidic devices are provided for conducting fluid assays, for example biological assays, that have the ability to move fluids through multiple channels and pathways in a compact, efficient, and low cost manner. Discrete flow detection elements, preferably extremely short hollow flow elements, with length preferably less than 700 micron, preferably less than 500 micron, and internal diameter preferably of between about 50+/−25 micron, are provided with capture agent, and are inserted into microfluidic channels by tweezer or vacuum pick-and-place motions at fixed positions in which they are efficiently exposed to fluids for conducting assays. Close-field electrostatic attraction is employed to define the position of the elements and enable ready withdrawal of the placing instruments. The microfluidic devices feature flow elements, channels, valves, and on-board pumps that are low cost to fabricate accurately, are minimally invasive to the fluid path and when implemented for the purpose, can produce multiplex assays on a single portable assay cartridge (chip) that have low coefficients of variation. Novel methods of construction, assembly and use of these features are presented, including co-valent bonding of selected regions of faces of surface-activatable bondable materials, such as PDMS to PDMS and PDMS to glass, while contiguous portions of one flexible sheet completes and seals flow channels, fixes the position of inserted analyte-detection elements in the channels, especially short hollow flow elements through which sample and reagent flow, and other portions form flexible valve membranes and diaphragms of pumps. A repeated make-and-break-contact manufacturing protocol prevents such bonding to interfere with moving the integral valve diaphragm portions from their valve seats defined by the opposed sheet member, which the flexible sheet material engages. Preparation of two subassemblies, each having a backing of relatively rigid material, followed by their assembly face-to-face in a permanent bond is shown. Hollow detection flow elements are shown fixed in channels, that provide by-pass flow paths of at least 50% of the flow capacity through the elements; in preferred implementations, as much as 100% or more. Metallized polyester film is shown to have numerous configurations and advantages in non-permanently bonded constructions. A method of preparing detection elements for an assay comprises batch coating detection elements, or hollow flow elements by mixing and picking and placing the elements in flow channels of a microfluidic device, capturing the flow elements by bonding two opposed layers while sealing the flow channels.
US10252250B2
A process of producing a catalyst based on pentasil-type crystalline aluminosilicate is described, including the steps of (a) treating hydrous aluminum oxide with an aqueous, acid-containing medium, (b) mixing the hydrous aluminum oxide treated with aqueous, acid-containing medium from step (a) with an H-zeolite and (c) calcining the mixture obtained in step (b). In addition, a catalyst is disclosed which is obtained by such a process, as well as its use in CMO and OTO processes.
US10252243B2
A process for producing black powder oxygen carriers for use in a chemical looping combustion unit includes the steps of: (a) removing and collecting the black powder waste material that was formed in a gas pipeline; (b) pre-treating the collected black powder to adjust its spherical shape to avoid attrition and fines production; and (c) activating the black powder to increase its reactivity rate and produce the black powder oxygen carrier that is suitable for use in the chemical looping combustion process as an oxygen carrier.
US10252233B1
In an embodiment, a cell assembly for use in a high-pressure cubic press may include at least one can assembly containing a diamond volume. The at least one can assembly may include an end surface in proximity to the diamond volume. The cell assembly may include at least one heating element including a major surface generally opposing and positioned adjacent to the end surface of the at least one can assembly. The at least one heating element may be positioned and configured to heat the diamond volume. The cell assembly may include at least one pressure transmitting medium extending about the at least one can assembly, and a gasket medium that defines a receiving space configured to receive the at least one can assembly, the one or more heating elements, and the at least one pressure transmitting medium.
US10252228B2
The present invention concerns a method and a device for feeding at least one chemical substance into a main process stream. The method of the invention comprises the steps of providing a concentrated stream of said chemical substance, mixing said concentrated stream with a diluent stream to provided a diluted stream of said chemical substance, injecting said diluted stream of said chemical substance into said main process stream, wherein said mixing of said concentrated stream with said diluent stream is effected by injecting a jet of either one of said concentrated stream or said diluent stream into the respective other stream. The device of the invention comprises a first pipe segment (21) having a first inlet (22) for a first fluid and a first outlet (23) for a mixed fluid, a second pipe segment (24) having a second inlet (25) for a second fluid and a second outlet (26) connected to and leading into said first pipe segment (21) between said first inlet (23) and said first outlet (24), and first connection means (27) for connecting said first outlet (23) of said first pipe section (21) to a main pipe (14) of said main process stream, wherein said second pipe segment (24) comprises at least one nozzle (28) for generating a jet (29) of said second fluid arranged upstream of said second outlet (26).
US10252223B2
To make membranes, a plurality of membrane substrates are each wetted with a curable liquid mixture, arranged in a stack such that every pair of substrates are separated by at least one film, and moved simultaneously through a common curing region. Each wetted substrate sheet may be sandwiched between two films. After curing, the stack comprises two or more membranes with each pair of membranes separated by a film. An apparatus for making membranes comprises at least two substrate feeding devices, at least one film feeding device, one or more chemical wetting devices, a curing region, optionally, a stack separating region, and, optionally, a membrane binding or fusing region. Membrane production rate may be increased while the curing energy required per unit area of membrane is decreased. The method can make, for example, ion exchange membranes.
US10252214B2
A carbon dioxide separation and recovery system includes: an adsorption reactor, which adsorbs, by an adsorbent, carbon dioxide contained in a to-be-treated gas, discharges the to-be-treated gas from which the carbon dioxide has been removed, and discharges the adsorbent that has adsorbed the carbon dioxide; a desorption reactor, which receives the adsorbent discharged from the adsorption reactor, condenses desorbing steam on the adsorbent to cause carbon dioxide to desorb from the adsorbent, and then discharges the adsorbent; and an adsorbent dryer, which receives the adsorbent discharged from the desorption reactor, dries the adsorbent until a water content ratio thereof becomes a predetermined value greater than or equal to a water content ratio limit by causing, with use of a drying gas, condensation water contained in the adsorbent to evaporate as steam, and then discharges the adsorbent.
US10252213B2
Provided is a dehumidification apparatus with good energy efficiency. A moisture absorbing material (polymeric moisture absorbing material 24), which absorbs moisture and swells at a temperature not higher than a predetermined temperature sensitive point, while shrinking and releasing condensed water at a temperature higher than the temperature sensitive point as a result of phase transition, is formed so as to be divided into a plurality of segments which are made apart from each other during dehydration. A rotation motor (21) is used to move the moisture absorbing material (polymeric moisture absorbing material 24) between a moisture absorption region (14a) and a dehydration region (14b). In the dehydration region (14b), the moisture absorbing material (polymeric moisture absorbing material 24) is heated by the heater (25).
US10252211B2
A process for removing halogen compounds, particularly chlorine compounds, from a process fluid, includes the steps of (i) passing a process fluid containing hydrogen halide over a first sorbent to remove hydrogen halide and generate a hydrogen halide depleted process fluid and then, (ii) passing the hydrogen halide depleted process fluid over a second different sorbent to remove organic halide compounds therefrom. A purification system suitable for removing hydrogen halide and organic halide compounds from process fluids is also described.
US10252204B2
An air conditioner including a suction inlet configured to suction air, a filter movably arranged at one side of the suction inlet, a first dust elimination member provided within a movement section of the filter to eliminate dust thereof by coming in contact with the filter when the filter is moved and a second dust elimination member provided adjacent to one side of the first dust elimination member to eliminate dust collected at the first dust elimination member, wherein the first dust elimination member is reversely rotated with respect to a movement direction of the filter to come in contact with the second dust elimination member, thereby eliminating the dust collected at the first dust elimination member.
US10252201B2
The prevent invention addresses the problem of providing a multilayer filter medium for a filter having low pressure loss and high collection efficiency, a method for producing the same, and an air filter not only having low pressure loss and high collection efficiency but also being excellent in pleatability and wind-pressure deformation resistance. The multilayer filter medium for a filter as a means for resolution is obtained by laminating a wet-laid nonwoven fabric layer (2) on a wet-laid nonwoven fabric layer (1). The wet-laid nonwoven fabric layer (1) includes a nanofiber A having a single-fiber diameter within a range of 200 to 800 nm and a fiber length within a range of 0.4 to 0.7 mm, a fiber B having a greater single-fiber diameter than the nanofiber A, and a binder fiber C. The wet-laid nonwoven fabric layer (2) includes a nanofiber A having a single-fiber diameter within a range of 200 to 800 nm and a fiber length within a range of 0.4 to 0.7 mm, a fiber B having a greater single-fiber diameter than the nanofiber A, and a binder fiber C, the weight proportion of the nanofiber fiber A being greater than in the wet-laid nonwoven fabric layer (1).
US10252197B2
A filter assembly includes a manifold with a base and a support ring. The support ring is received within the base such that the support ring is rotatable relative to the base. A housing of the filter cartridge has an interface positioned at an outer surface of the housing. The interface is configured to engage with a post of the support ring in order to mount the filter cartridge to the manifold.
US10252196B2
A filtering apparatus includes a screen assembly removably positioned within an inner cavity of a screen chamber. The screen assembly includes a frame portion at a first end and a screen portion extending from the frame portion to a second end. The frame portion includes an end block and frame members interconnecting the end block and the screen portion. The screen portion includes an outer screen and an inner screen disposed within an interior space of the outer screen. An outer wall of the outer screen and an outer wall of the inner screen each includes a plurality of openings. The screen chamber includes a removable end cover with a key for rotationally locking the screen assembly in the inner cavity. A screen manifold may include a first fluid path including the screen chamber, and further including a bypass fluid path having a bypass valve.
US10252183B2
Improvements in biological conversion processes and associated apparatuses are disclosed for the generation of useful end products such as ethanol, through metabolic pathways of C1-fixing bacteria that utilize, as a nutrient, a C1-carbon source from a C1-containing substrate such as an industrial waste gas. Particular aspects of the disclosure relate to the downstream recovery of ethanol and/or isopropanol from bleed and permeate streams and more particularly to performing such recovery with improved efficiency that can advantageously reduce capital (e.g., equipment) and/or operating (e.g., utility) costs.
US10252175B2
There is provided an article, the article being moveable between a first position and a second position and biased to the second position. The article is retained in the first position until a predetermined condition is met, and wherein when said predetermined condition is met the article moves from the first position to the second position.
US10252174B2
A balloon includes two joined plastic films. The balloon includes: a gas supply valve sandwiched between and joined to the first film and the second film; a first chamber receiving air supplied from the gas supply valve for expansion; and a second chamber communicating to the first chamber. The gas supply valve includes a gas passage that extends from a gas inlet positioned on an outer side of the second chamber to an inside of the first chamber through the second chamber. Part of the first film and the second film between the first chamber and the second chamber and between the gas passage and a peripheral edge of the balloon are joined together to form a first weld portion and a second weld portion. The first weld portion is formed on an opposite side of the second weld portion with the gas passage sandwiched therebetween.
US10252173B2
An adapter for use in a video game controller includes a housing having a shape adapted to be securely placed in a compartment or attached to the controller; a console port adapted to interface with a game console for transmitting game information and actions to the game console; a controller port adapted to interface with the controller to receive game functions from the controller; at least one game actuator; and a function control module operatively connected to the console port, the controller port and the at least one game actuator mechanism.
US10252172B2
An example information sharing system includes: an executing unit that executes an application program according to operations of one of a plurality of users; a recording unit that records replay data for replicating an execution process of the application program; a generating unit that generates shared information associated with the application program based on operations of the one of the plurality of users; and a sharing unit that shares the generated shared information and the recorded replay data with the plurality of users.
US10252164B2
A game system has a server managing a game to a first platform comprising a head-mounted display (HMD) and a three-axis controller, where a movement of a first avatar is made by marking a position to move and teleporting the to the marked position, and managing the same game to a second platform comprising a pointer device and a display screen, where movement of a second avatar is by the pointer device at a pre-programmed rate. Procession of the game is displayed in the HMD from viewpoint of the first avatar, and in the display of the second platform from viewpoint of the second avatar, both avatars being displayed in both displays, and wherein the game server, executing the SW, constrains teleportation at the first platform only to positions within a radius that the second avatar is enabled to attain in a single continuous move at the pre-programmed rate.
US10252163B2
A music based video game provides a user directed sound generation feature. In some embodiments, the user is provided a video game controller simulating a musical instrument, which the user may operate similarly to its real musical instrument counterpart. A free play feature is provided for users to operate the video game controller, where a processor of a video game console receives input signals from the video game controller and outputs audio samples based on the received input signals. During the free play feature, multiple suggestions as to how to operate the video game controller are simultaneously provided to give users some guidance as to what to play using the video game controller.
US10252160B2
Customized wait state experiences for an avatar in a virtual universe are provided by determining user alternative wait context preferences, selecting alternative wait state content objects accordingly, creating a wait state context in the virtual universe system using the alternative wait state content objects, and transporting the waiting avatar to the newly created wait state context for the duration of the wait. The custom context can include scenery, sounds, and even information streams and feeds. The avatar is optionally returned to the original context upon an event, such as a customer service representative, being available and ready to interact with the user. Artificial intelligence processes are optionally used to determine probable wait state context preferences for the user. Rewards may be given to the user for waiting, and for completing games or challenges.
US10252154B2
In one aspect, a device includes a processor and storage accessible to the processor. The storage bears instructions executable by the processor to determine a user of a headset and transmit, based on the determination of the user, a first portion of content of a first rating to the headset for presentation at the headset concurrently with presentation of a second portion of the content on a display separate from the headset. The second portion is of a second rating different from the first rating of the first portion.
US10252143B1
An aquatic timing system includes a plurality of timing apparatuses, each timing apparatus including a primary portion with a front touch area and a display for presenting visual information, the display forming part of the front touch area. Each timing apparatus further includes a flange portion extending from an edge of the primary portion and a sensor for detecting a touch event occurring on the front touch area of the primary portion. An enclosure is mounted on the flange portion and contains a controller in communication with the sensor. The controller is configured to receive a signal from the sensor and identify a touch event from the signal, communicate a wireless signal to an external device including event time information associated with the timing apparatus, and receive a wireless signal containing event information and cause the display to present the event information.
US10252128B2
A ball throwing machine can include a hopper for receiving one or more balls and a ball delivery device. The ball delivery device can be used to throw or pitch a ball from the hopper to a user of the machine. The ball delivery device can include wheels to impart speed to the ball and a direction system to control the projection angle of the ball. The direction system can control at least one of the up and down angle and the side to side angle of the ball as it is thrown, among possibly other throwing parameters. A controller may be provided for controlling operation of the ball throwing machine.
US10252126B2
A lacrosse head having string holes and/or sidewall openings that are offset at an angle relative to a longitudinal axis of the lacrosse head, and a related method of manufacture, are provided. The lacrosse head includes a pair of sidewalls extending from the base and joined with one another distal from the base at the scoop. A longitudinal axis can extend from the base toward the scoop. The sidewalls can define string holes, each having a string hole axis disposed at a non-perpendicular angle relative to the longitudinal axis, optionally 5° to 75°, further optionally 25° to 35°, and even further optionally 30°. The sidewalls can define one or more sidewall openings each having a sidewall opening axis disposed at a non-perpendicular angle relative to the longitudinal axis, such as those noted above. A related method of manufacture also is provided.
US10252123B2
Embodiments of golf club heads and methods to manufacture golf club heads are generally described herein. In one example, the method of manufacturing a golf club head may include providing a body portion and providing a plurality of weight portions. The body portion may include a front portion, a rear portion, a toe portion, a heel portion, a top portion, a bottom portion having an outer surface associated with an outer surface curve, and a weight port region located at or proximate to the bottom portion. Other examples and embodiments may be described and claimed.
US10252122B2
A golf club head has a high COR, is durable, and has desirable acoustic qualities. The club head includes a body portion, a striking face and a crown forming a hollow cavity of at least 150 cc in volume. The body portion defines a front opening and an upper opening, and it includes a sole and a side section that extends rearward of the front opening. The striking plate is secured to the body portion, enclosing the front opening. While partially assembled, final weighting and/or other attachment of other members to the inner surface of the club head can be preformed, as desired. The crown is secured to the body portion, enclosing the upper opening. A surface veil may also be provided about a junction of the crown and body.
US10252110B2
A hand cover apparatus with a tensioning mechanism that tensions a portion of the apparatus such that it is urged to retract to an open position, freeing a portion of the user's hand. Said system has one stationary piece and at least one additional piece that moves relative to it and can be triggered to free the hand by using only the hand to which it is mounted.
US10252109B2
A treadmill includes a deck, a first pulley disposed in a first portion of the deck, a second pulley disposed in a second portion of the deck, a tread belt surrounding the first pulley and the second pulley, and a platform incorporated into the deck.
US10252104B2
The invention relates to a sports mat which consists of a flexible material and has a longitudinal direction (L) and a transverse direction (Q) perpendicular thereto, comprising a rectangular mat longitudinal subarea (2) and a rectangular mat transverse subarea (3) which intersects the mat longitudinal subarea (2) forming a T shape, an extension of the mat longitudinal subarea (2) in the transverse direction (Q) along a leg section (6) of the T being not more than half the size than a longest transverse extension of the mat transverse subarea (Q).
US10252096B2
An adjustably-tensioned, transverse-suspended elastic element exercise device is disclosed. The transverse element is suspended between frame elements sized so as to enable full range of motion exercises. The tension and height of the elastic member can be adjusted so as to accommodate varying exercise levels and positions. The assembly may include handgrips and attachments to augment workouts. Electronic adjustability, metrics, programmability and Internet connectivity enhance the user experience. A method of using the device is also disclosed.
US10252089B2
A monitoring apparatus for monitoring a wearer of a breathing apparatus including a source of breathable gas which is supplied to a delivery device via a fluid line, the monitoring apparatus including a breathing detector arranged to determine if breathing using the breathing apparatus has commenced, and a mobile monitoring device arranged to be associated with the wearer and which can be activated to monitor the motion of the wearer. The monitoring apparatus is arranged to activate the mobile monitoring device when it is determined that breathing has commenced.
US10252082B2
A method is disclosed for irradiation planning for the irradiation of a moving target volume located in a body with a particle beam irradiation facility by means of rescanning, which method has the steps of defining the target volume in a reference condition of the motion, dividing the target volume among a plurality of target points that can be individually approached with a particle beam, calculating a nominal dose to be deposited in each of the target points of the target volume, defining a number of rescanning passes in which each of the target points of the target volume are approached, calculating a mean motion to be expected of the target points of the target volume based on a motion model, taking into account the mean motion to be expected of the target points of the target volume in the irradiation planning in such a manner that the deviation of the expected dose deposition from the nominal dose for each target point is determined, and the nominal dose for each target point is corrected on the basis of the deviation, and generation of control parameters for the irradiation facility, wherein the control parameters comprise a particle count per target point and rescanning pass to be applied.
US10252078B2
Provided herein are ophthalmic phototherapy devices and associated phototherapy methods for promoting healing of damaged or diseased eye tissue. An ophthalmic phototherapy device includes a light emitting mechanism for transmitting light of at least one preselected wavelength to the eye tissue. An ophthalmic phototherapy method includes directing light of at least one wavelength for a selected period of time to a portion of damaged or diseased eye tissue, whereby the light transmitted to the damaged or diseased eye tissue stimulates cellular activity in the eye tissue to promote healing.
US10252075B2
The invention relates to an ocular therapy device having a radiation source emitting UV light and an optical imaging system disposed downstream of the radiation source for imaging a therapy beam coming from the radiation source in an ocular imaging plane, wherein an optical condenser unit is disposed downstream of the radiation source and comprising a diaphragm unit, an optical means for influencing a spatial energy distribution which can be associated with the therapy beam and is oriented along the therapy beam cross-section, and comprising an optical means for influencing a beam form, which can be associated with the therapy beam.
US10252069B1
Systems and methods for detecting lead anomalies by detecting overcurrent conditions caused by the delivery of high voltage test pulses configured to minimize patient sensation. Patient sensation is minimized by limiting the total charge delivered in either a positive or negative test pulse by limiting duration, and/or by cancelling nerve activations by delivery of an opposite phase cancellation pulse as part of a biphasic test pulse. Embodiments include high-speed H-bridge switches, and micro-coulomb test capacitors to control total charge and duration. Embodiments detect anomalies when an overcurrent circuit detects a current above a threshold passing through an electrode that is not directly energized.
US10252067B2
A method and medical device for adjusting a blanking period that includes sensing cardiac signals from a plurality of electrodes, the plurality of electrodes forming a plurality of sensing vectors, determining whether to adjust a blanking period during a first operating state, advancing from the first operating state to a second operating state in response to the sensed cardiac signals, determining, while in the second operating state, whether the blanking period was adjusted while in the first operating state, and adjusting the blanking period while in the second operating state in response to the blanking period being adjusted while in the first operating state.
US10252064B2
Disclosed is a plug-in accessory for operating a mobile device as an external controller for an Implantable Medical Device (IMD). The accessory includes a connector insertable into a port on the mobile device. Accessory circuitry can be powered by a battery or by the mobile device. An application on the mobile device in conjunction with the accessory configures the mobile phone for immediate use as an IMD external controller. When the accessory is inserted into the port or a switch on the accessory pressed, the application operates to validate the accessory; to unlock the phone; to secure the mobile device; and to render a graphical user interface on the mobile device for communicating with the IMD. The accessory can additionally include telemetry circuitry and an antenna for communicating with the IMD, rather than using short-range communication means provided in the mobile device itself.
US10252057B2
A method of reducing bronchial constriction in a subject includes delivering energy to create one or more lesions on a main bronchus so as to transect pulmonary nerves sufficiently to reduce bronchial constriction in a lung of the patient distal to the main bronchus.
US10252052B2
The invention contemplates, inter alia, the use of remote ischemic conditioning in the treatment of a variety of disorders.
US10252048B2
Described here are devices, systems, and methods for treating one or more conditions, such as allergic rhinitis, non-allergic rhinitis, nasal congestion, ocular allergy, and/or symptoms associated with these conditions, by providing stimulation to nasal or sinus tissue. In some variations, the handheld devices may have a stimulator body and a stimulator probe having one or more nasal insertion prongs, and the nasal insertion prongs may be configured to deliver an electrical stimulus to the tissue.
US10252047B2
The neural interface system of one embodiment includes a cylindrical shaft, a lateral extension longitudinally coupled to at least a portion of the shaft and having a thickness less than a diameter of the shaft, and an electrode array arranged on the lateral extension and radially offset from the shaft, including electrode sites that electrically interface with their surroundings. The method of one embodiment for making the neural interface system includes forming a planar polymer substrate with at least one metallization layer, patterning on at least one metallization layer an electrode array on a first end of the substrate, patterning conductive traces on at least one metallization layer, rolling a portion of the substrate toward the first end of the substrate, and securing the rolled substrate into a shaft having the first end of the substrate laterally extending from the shaft and the electrode array radially offset from the shaft.
US10252046B2
A peelable lid system includes a peelable lid, a seal configured to seal the peelable lid to a container, a handle coupled to the peelable lid, and a lifting mechanism coupled to handle. The lifting mechanism can be coupled to the peelable lid at a plurality of attachment points, including at least one attachment point coupled to the peelable lid away from the handle. The lifting mechanism can be configured to lift at least one portion of the peelable lid near each of the plurality of attachment points.
US10252045B2
The invention relates to a connector/cap assembly comprising locking means and coupling means allowing the cap to be removed from the connector using only one hand and preferably without the cap coming into contact with the hand of the practitioner.
US10252029B2
A catheter or guide wire manipulating device with two-point-clamping for vascular intervention is provided, comprising a thumb component (3), a forefinger component (4), a driving component (1) and a catheter/guide wire support component (2); the thumb component (3) comprises a pair of rollers (9, 10) configured to advance or retreat the catheter/guide wire; the thumb component (3) is configured to drive the catheter/guide wire to rotate clockwise or counterclockwise through a combination motion of the components; the forefinger component (4) is configured to implement the rotation and the advancement of the catheter/guide wire by moving manually away from the thumb component (3), and returning by a pull force of a spring (27) after being released; the driving component (2) is configured to drive the thumb component (3) and the forefinger component (4); the catheter/guide wire support component comprises a Y adapter fixation configured to install a Y adapter and an entry support configured to support and guide the catheter/guide wire into a mechanism.
US10252025B2
A urinary prosthesis can include an elongate tube that can extend from outside a patient's body, through the patient's urethra, and into the patient's bladder. A funnel can be coupled to a terminal end portion of the elongate tube, and can be positioned inside the patient's bladder so that a surface of the funnel contacts tissue within the patient's bladder surrounding the patient's urethra across a full 360° contact profile.
US10252022B2
A lighting control device for influencing thermoregulation of a vertebrate is disclosed. In one example, the lighting control device configured to select, on the basis of a predetermined criterion, a particular group of colors of groups having been categorized into groups on the basis of dominant wavelength, where each group of colors is arranged to influence a vertebrate's thermoregulation in a particular manner, and configured to generate a control signal for controlling the dominant wavelength of light emitted from at least one light source in accordance with the selected group of colors. The lighting control device is configured to transmit the generated control signal to said at least one light source for said at least one light source to emit light of the selected group of colors, thereby influencing the thermoregulation of the vertebrate being exposed to the light on the basis of said predetermined criterion.
US10252018B2
Various implementations include a gas delivery and monitoring apparatus that can be used, for example, to deliver oxygen and monitor exhaled carbon dioxide in a subject while under anesthesia. One advantage of the disclosed apparatus is the ability to deliver oxygen directly to the back of the mouth instead of in front of the face. Another advantage of the disclosed apparatus over existing nasal cannulas is the ability to capture carbon dioxide exhaled from both the nose and mouth.
US10252015B2
In one embodiment, a nasal cannula is shaped to fit within a user's nares, where the nasal cannula includes at least one prong allowing high flow delivery of humidified gases and creates positive airway pressure in the patient's airway. The prongs have angled ends such that, in use, gases flowing through the prongs are directed to the user's nasal passages. The nasal cannula body is partially swivelling and preferably has a ball joint connector. In another embodiment the nasal cannula may have at least one flared end prong that preferably seals within a patient's nare.
US10252004B2
Methods and apparatus for the reproducible, consistent and efficacious delivery of a therapeutic agent to a patient. The invention comprises means for the controlled administration of the therapeutic agent through an orifice to the patient, a plurality of penetrating electrodes arranged with a predetermined spatial relationship relative to the orifice, and means for generating an electrical signal operatively connected to the electrodes.
US10251996B2
A variable rate controlled delivery drive mechanism includes a drive mechanism housing, at least partially within which initially resides a biasing member positioned in an initially energized state within an inner cavity of a piston. The drive mechanism may include a gear drive having one or more screws and one or more corresponding nuts. The piston contacts a plunger seal and is configured to axially translate the plunger seal, by force asserted upon it from the biasing member, from a first position to a second position within a drug container for drug delivery. The biasing member is metered from free expansion from its energized state by the gear drive and a gear assembly mechanism having a motor. A drug delivery pump utilizes such variable rate controlled delivery mechanisms. A status reader configured to recognize one or more corresponding status triggers is utilized to provide feedback to a user.
US10251992B2
A chamber for a blood treatment system having a blood inlet and a blood outlet, a filter element for air separation which is arranged at the head side with respect to the position of the chamber in the operating state, and which can be decoupled from the blood present in the chamber in the operating state via a further liquid.
US10251983B2
Methods and apparatuses for automatically switching different aspiration levels to an ocular probe are disclosed herein. The probe may be a phacoemulsification probe. A first aspiration level, supplied by a first pump, may be applied to the probe simultaneously with ultrasonic energy. A second aspiration level, supplied by a second pump, may be automatically switched from the first aspiration level. Control feed back of the pumps may be varied according to set thresholds.
US10251982B2
New ampholyte biomaterial compounds containing ampholyte moieties are synthesized and integrated into polymeric assemblies to provide hydrophilic polymers exhibiting improved biocompatibility, haemocompatibility, hydrophilicity non-thrombogenicity, anti-bacterial ability, and mechanical strength, as well as suitability as a drug delivery platform.
US10251977B2
Described herein are compositions comprising decellularized extracellular matrix derived from skeletal muscle or other suitable tissue, and therapeutic uses thereof. Methods for treating, repairing or regenerating defective, diseased, damage, ischemic, ulcer cells, tissues or organs in a subject preferably a human, with diseases, such as PAD and CLI, using a decellularized extracellular matrix of the invention are provided. Methods of preparing culture surfaces and culturing cells with absorbed decellularized extracellular matrix are provided.
US10251969B2
An HVAC fluid dispersant system. The HVAC fluid dispersant system includes one or more fluid lines, the one or more fluid lines configured to allow movement of a fluid and a pump, the pump configured to move the fluid through the one or more fluid lines. The HVAC fluid dispersant system also includes a source line, the source line configured to provide the fluid to the pump and a nozzle. The nozzle is configured to receive the fluid from the one or more fluid lines, create a mist composed of the fluid and attach to a duct vent.
US10251967B1
An aromatherapy candle waterlamp including: a waterlamp main body, a container, a bottom case and a top-cover. The main body is filled with a flowing liquid and set a hollow channel. The container is set in the top of the main body and the bottom case is fixedly connected with the bottom of the main body. A control circuit, a power module for supplying power, a light source, an electricity conductive wire, and an electric heating piece are set inside the bottom case. The light source irradiates toward the bottom of the main body. The electricity conductive wire is partially set through the hollow channel of the waterlamp main body and is electrically connected with an electric heating piece. The top-cover having a three-dimensional shape is set for correspondingly covering the top of the main body and is alternately set with a plurality of through holes.
US10251952B2
Herein is reported a non-covalent complex of a haptenylated antibody that specifically binds to human tau(pS422) and an anti-blood brain barrier receptor/hapten bispecific antibody.
US10251942B2
An immunity-inducing agent comprising as an effective ingredient(s) a polypeptide(s) selected from the polypeptides: (a) a polypeptide consisting essentially of not less than 7 consecutive amino acids in any one of the amino acid sequences shown in SEQ ID NOs:2, 4, 6, 8, 10, 12 and 44 in SEQUENCE LISTING; (b) a polypeptide having a sequence identity of not less than 90% with the polypeptide (a) and consisting essentially of not less than 7 amino acids; and (c) a polypeptide comprising the polypeptide (a) or (b) as a partial sequence thereof; which polypeptide(s) has/have an immunity-inducing activity/activities, or as an effective ingredient(s) a recombinant vector(s) which comprise(s) a polynucleotide(s) encoding the polypeptide(s) and is/are capable of expressing the polypeptide(s) in vivo, is useful as a therapeutic and/or prophylactic agent for cancer, and/or the like.
US10251940B2
A composition comprising a complex of Factor VIII and one or more Von Willebrand Factor peptides, wherein the Von Willebrand Factor peptides comprise at least the amino acids 764 to 1035 and 1691 to 1905 of SEQ ID No. 1 but not amino acids 2255 to 2645 of SEQ ID No. 1.
US10251938B2
The present invention provides methods for treating, preventing or reducing the severity of cerebral malaria. The methods of the present invention comprise administering to a subject in need thereof a therapeutically effective amount of a pharmaceutical composition comprising a modified angiopoietin molecule such as AngF1-Fc-F1.
US10251936B2
The present invention relates to an EBV antigen specific T-cell receptor and the use thereof. Specifically, the present invention provides T cells specific for LMP1 of EBV using a T-cell receptor which is highly specific for specific epitopes derived from an EBV antigen, LMP1. In addition, the EBV antigen specific T-cell can be used in the prevention or treatment of EBV-associated diseases.
US10251930B2
The invention provides a method of treating a degenerative joint disease. The method comprises administering an effective amount of a pharmaceutical composition comprising a diketopiperazine with amino acid side chains of aspartic acid and alanine (DA-DKP). The invention also provides a pharmaceutical product as well as a kit comprising DA-DKP.
US10251928B2
The present disclosure relates to nutritional supplement including a peptide component. The nutritional supplement further includes a source of long-chain polyunsaturated fatty acids and Lactobacillus rhamnosus GG. The disclosure further relates to methods of protecting against obesity and its related metabolic disorders and inflammatory diseases in a target subject by providing the nutritional supplement(s) disclosed herein to a target subject, which includes a pediatric subject.
US10251926B2
The present invention relates to a process for preparing an extract from one or more botanical raw materials, such as Indigo Naturalis and the extract itself. The present invention also relates to a composition comprising the extract, as well as the use of composition in medical or cosmetic applications.
US10251923B2
The invention relates to therapeutic uses of gum mastic, and compounds found therein including polymeric myrcene. More particularly, the invention relates to methods of treating impaired neurological function using compositions comprising polymeric myrcene.
US10251922B2
Described herein are chimeric Newcastle disease viruses engineered to express an agonist of a co-stimulatory signal of an immune cell and compositions comprising such viruses. Also described herein are chimeric Newcastle disease viruses engineered to express an antagonist of an inhibitory signal of an immune cell and compositions comprising such viruses. The chimeric Newcastle disease viruses and compositions are useful in the treatment of cancer. In addition, described herein are methods for treating cancer comprising administering Newcastle disease viruses in combination with an agonist of a co-stimulatory signal of an immune and/or an antagonist of an inhibitory signal of an immune cell.
US10251920B2
The invention relates to new isolated Lactobacillus and Bifidobacterium strains which have been isolated from fresh honey having a water content above 18% by weight or from the honey producing tract of at least one bee. The bacterial strains have unique properties rendering them useful in many products such as in food and beverage products, feed products, and medica products.
US10251913B2
The present invention relates to a composition comprising polysaccharides and whey protein micelles for use in the treatment or prevention of a disorder linked to an increase in plasma postprandial insulin in a subject. The invention relates also to the non-therapeutic use of a composition comprising polysaccharides and whey protein micelles to decrease plasma postprandial insulin concentration. A further aspect of the invention is a process for forming polysaccharide-whey protein micelle complexes.
US10251904B2
Provided are methods for treating Arenaviridae and Coronaviridae virus infections by administering nucleosides and prodrugs thereof, of Formula I: wherein the 1′ position of the nucleoside sugar is substituted. The compounds, compositions, and methods provided are particularly useful for the treatment of Lassa virus and Junin virus infections.
US10251902B2
The present invention provides a pharmaceutical composition or a food composition comprising, as active ingredients, flavone-6-C-glucose derivatives or galenical extracts containing flavone-6-C-glucose derivatives. The composition of the present invention shows a functional effect of effectively treating or preventing cognitive dysfunction disorders such as delirium, dementia or amnesia, stroke, palsy, attention disorders, anxiety disorders or sleep disorders.
US10251901B2
The present invention relates to a formulation of thermosensitive liposomes, and more specifically to a formulation of liposomes comprising phospholipids and a surface active agent, wherein the liposomes support long term storage at temperatures less than or equal to about 8° C., control degradate formation to maximize product potency and release their contents at mild hyperthermic temperatures. Methods of making formulations are also described.
US10251892B2
The present disclosure relates to bicyclic heterocycles of Formula (I′), and pharmaceutical compositions of the same, that are inhibitors of the FGFR3 and/or FGFR4 enzyme and are useful in the treatment of FGFR-associated diseases.
US10251890B2
The present invention provides compounds of the formula (I) wherein: X1, X2 and X3 are heteroatoms; R4, R5, R6, R7, R8, R9 and R10 are independently selected from H, halo, —OH, —NO2, —CN and optionally substituted aliphatic, cycloalkyl, heterocycloalkyl, aryl or heteroaryl; and Z is optionally substituted C1-8 straight-chained or branched aliphatic, optionally containing 1 or more double or triple bonds, wherein one or more carbons are optionally replaced by R* wherein R* is optionally substituted cycloalkyl, heterocycloalkyl, aryl or heteroaryl; an amino acid residue, H, —CN, —C(O)—, —C(O)C(O)—, —C(O)NR1—, —C(O)NR1NR2—, —C(O)O—, —OC(O)—, —NR1CO2—, —O—, —NR1C(O)NR2—, —OC(O)NR1—, —NR1NR2—, —NR1C(O)—, —S—, —SO—, —SO2—, —NR1—, —SO2NR1—, —NR1R2, or —NR1SO2—, wherein R1 and R2 are independently selected from H and optionally substituted aliphatic, cycloalkyl, heterocycloalkyl, aryl or heteroaryl; or where R* is NR1R2, R1 and R2 optionally together with the nitrogen atom form an optionally substituted 5-12 membered ring, said ring optionally comprising 1 or more heteroatoms or a group selected from —CO—, —SO—, —SO2— and —PO—; or a pharmaceutically acceptable salt, ester or prodrug thereof.
US10251889B2
Compounds of Formula I: and salts thereof in which R1, R2, R3, R4, X, Y and n have the meanings given in the specification, are inhibitors of Trk kinases and are useful in the treatment of diseases which can be treated with a Trk kinase inhibitor such as pain, cancer, inflammation, neurodegenerative diseases and certain infectious diseases.
US10251885B2
The present invention relates generally to antifugal compositions. In an embodiment, the antifungal compositions are effective for application to nails and surrounding skin, and comprise at least one volatile solvent, at least one film forming substance, and at least one pyrimidone derivative of formula I, such as albaconazole. These compositions are capable of treating an infection caused by fungi, such as onychomychosis.
US10251882B2
Disclosed herein are aza-pyridone compounds, pharmaceutical compositions that include one or more aza-pyridone compounds, and methods of synthesizing the same. Also disclosed herein are methods of ameliorating and/or treating a disease and/or a condition, including an orthomyxovirus infection, with an aza-pyridone compounds. Examples of an orthomyxovirus viral infection include an influenza infection.
US10251881B2
Embodiments of the invention relate to particles of active substances, methods for preparing the particles, formulations containing the particles, and metered dose inhalers containing such particles or formulations. In one embodiment, a composition of an aerosol formulation is provided and contains a particulate active substance of non-micronized, solid particles having a mass median aerodynamic diameter of less than 10 μm suspended in a hydrofluorocarbon fluid vehicle at a concentration within a range from about 0.2% w/v to about 5% w/v. The aerosol formulation exhibits a flocculation volume of about 85% or greater about 1 minute after mixing the particulate active substance and the hydrofluorocarbon fluid vehicle. The particulate active substance contains an alkaloid ergotamine, pharmaceutically acceptable salts thereof, analogues thereof, or derivatives thereof. In some examples, the alkaloid ergotamine contains dihydroergotamine, such as dihydroergotamine mesylate and the hydrofluorocarbon fluid vehicle contains HFA 134a, HFA 227ea, or mixtures thereof.
US10251880B2
Provided herein are methods of utilizing bile acid transport inhibitors and/or enteroendocrine peptide enhancing agents for the treatment of obesity, diabetes, and inflammatory gastrointestinal conditions.
US10251869B2
A method of treating a bacterial infection in a subject in need thereof includes administering to the subject therapeutically effective amounts of at least one β-lactam antibiotic and at least one bisthiazolidine metallo-β-lactamase inhibitor.
US10251866B2
The present invention in general relates to a pharmaceutical suspension comprising nano-sized cocrystals of at least one active ingredient and at least one dicarboxylic acid. It in particular relates to a pharmaceutical suspension comprising nano-sized cocrystals of at least one anthelmintic drug and at least one dicarboxylic acid. The invention further relates to uses, methods for use and methods for manufacturing the pharmaceutical suspension according to this invention.
US10251863B2
The invention relates to oral, topical or injectable compositions for combating liver fluke parasites in mammals, comprising at least one indole derivative active agent. The invention also provides for an improved method for eradicating and controlling liver fluke parasite infections and infestations in a mammal comprising administering the compositions of the invention to the mammal in need thereof.
US10251862B2
The present invention relates to a cosmetic composition containing a hydroxypyranone derivative compound as an active ingredient for promoting the differentiation of adipocytes. The composition according to the present invention has an effect of promoting the differentiation of adipocytes, and thus allows the differentiation of adipocyte in a skin layer, thereby increasing the skin volume or elasticity. Therefore, the composition of the present invention can be variously used as a cosmetic composition or a pharmaceutical composition in the field, such as skin damage.
US10251858B1
A pharmaceutically active composition suitable for topical application to the nails contains undecylenic acid and tolnaftate. The composition also employs a urea-based component, a monohydric alcohol such as isopropanol, a diol such as propylene glycol, dimethyl isosorbide, and a carboxylic acid other than undecylenic acid, preferably lactic acid.
US10251846B2
The invention describes a pharmaceutical association of active ingredients comprising: curcumin, quercetin, chondroitin sulfate and hyaluronic acid, used for the prevention or treatment of bladder, pelvic and urogenital apparatus pathologies.
US10251842B1
Nanocapsules of bioactive compounds derived from natural products as an adjunct treatment for cancer. Nanocapsules of bioactive compounds showed synergy in the treatment of cancer therapy-induced toxicity.
US10251840B2
The invention relates to an improved method of manufacturing substantially spherical/ball-shaped tartaric acid starter pellets which are suitable for preparing active substance-containing medicament formulations, as well as the pellets as such that may be obtained in this way, and their use as starting material for the preparation of active substance-containing medicament formulations.
US10251839B2
Novel lipid vesicle compositions comprising lipids derived from olive oil fatty acids known as olivates, methods of their preparation, and methods of their use in cosmetics, food, dermatologics, and pharmaceuticals.
US10251836B2
A method and intravaginal drug delivery device for reducing size of endometrial implants in a female in need thereof are provided. The method includes administering intravaginally to the female a therapeutically effective amount of an active agent, wherein the agent is delivered on a delivery device directly to the endometrial implants, wherein said amount is able to significantly reduce the size of endometrial implants, wherein the active agent is any one of selective progesterone receptor modulator (SPRM), an anti-progestin agent, and an anti-progestational agent.
US10251833B2
Described herein are compositions that contract and reduce pore size. The compositions of the disclosure are also useful for collagen contraction of the skin, calming skin, and reducing oil on the skin. The compositions comprise cosmetic ingredients such as glycerin; cyclopentasiloxane; polysilicone-11; pentaerythrityl tetraethylhexanoate; dipropylene glycol; methyl methacrylate crosspolymer; betaine; bis-PEG/PPG-16/PPG-16/16 PEG/16 dimethicone; Albizia julibrissin bark extract; Evodia rutaecarpa fruit extract; hydrolyzed soy flour; sea whip extract; and a dermatologically acceptable vehicle.
US10251829B2
Cosmetic composition having a heating effect and used for the care and temporary shaping of keratin fibers and related methods are provided. The cosmetic composition can include at least one polyethylene glycol comprising 4 to 20 oxyethylene units; a copolymer composed of hydrogenated castor oil and an n-alkyl dicarboxylic acid comprising 4 to 10 C atoms; and at least one film-forming agent.
US10251805B2
Systems and methods for use with haptic devices. A control system for haptic devices determines a first course of action based on a user's motion. Prior to implementing the first course of action, the control system determines if the first course of action would lead to instability in the haptic device which could cause an unsafe situation such as failure of its components. If the first course of action would lead to instability, the control device determines a second course of action that would not lead to instability and implements this second course of action. To assist in this second course of action and to prevent potential oscillation in the haptic device, the control system also selectively dampens a projected action of the haptic device. A haptic device using such a control system is also disclosed.
US10251802B2
An apparatus for vibration of a person via a vibrating platform. The apparatus includes a support structure that has a fulcrum and a plurality of vibration isolators, a platform that has a central portion and lateral portions, a power assembly coupled to the platform to operably oscillate the platform about the fulcrum, and a base shell that extends around one or more sides of the platform. The central portion of the platform is pivotally coupled to and operably oscillates about the fulcrum of the support structure so that oscillation about the fulcrum causes the lateral portions to alternately rise and fall in a substantially vertical direction. Further, the base shell is mounted to the support structure free-from connectors other than the vibration isolators.
US10251790B2
A method for external ear canal pressure regulation to alleviate one or more symptoms associated with a disorder or treat one or more disorders, the method including providing a fluid transfer device which generates a fluid flow of a fluid through an earplug, the earplug having an earplug external surface configured to sealably engage an external ear canal wall as a barrier between an external ear canal pressure and an ambient pressure; sealably engaging the earplug of the fluid transfer device with the external ear canal wall as the barrier between the external ear canal pressure and the ambient pressure; and operating the fluid transfer device to generate the fluid flow of the fluid through the earplug to achieve an external ear canal pressure differential between the external ear canal pressure and the ambient pressure effective to alleviate a disorder symptom or treat a disorder.
US10251783B2
Methods and systems for tracking a position and torsional orientation of a patient's eye. In one embodiment, the present invention provides methods and software for registering a first image of an eye with a second image of an eye. In another embodiment, the present invention provides methods and software for tracking a torsional movement of the eye. In a particular usage, the present invention tracks the torsional cyclorotation and translational movement of a patient's eye so as to improve the delivery of a laser energy to the patient's cornea.
US10251779B2
Injection devices for delivering pharmaceutical formulations into the eye are described. The devices may be integrated to include features that allow safe and atraumatic manipulation of the devices with one hand. For example, accurate placement, including proper angulation, of the device on the eye and injection of a pharmaceutical formulation into the eye can be performed using one hand. The devices may also include improved safety features. For example, the devices may include an actuation mechanism that controls the rate and depth of injection into the eye. Some devices include a dynamic resistance component capable of adjusting the amount of pressure applied to the eye surface. Related methods and systems comprising the devices are also described.
US10251770B2
A valve for a pouch for collecting biological fluids includes a valve stem, at least a portion of which is formed from a polymeric material including oleamide.
US10251765B2
A stent delivery system, and associated manufacturing method, are such that the outer diameter of the distal portion of the stent delivery system is relatively small. The stent delivery system includes a hollow shaft portion, an inflatable balloon disposed on the outer periphery of a distal portion of the shaft portion, and a stent disposed on the outer periphery of the balloon and having struts expanded by inflation of the balloon. The balloon has a ridge portion with which the stent is engaged. The ridge portion is sandwiched in a space between the struts, and a top portion of the ridge portion has a concave portion recessed toward the axis of the shaft portion.
US10251756B2
Prosthesis for a shoulder joint including a humeral component equipped with a stem, a head component and connection or articulation means of the humeral component with the head component, wherein the prosthesis according to the invention can be used both as a conventional prosthesis and as a reverse-type prosthesis.
US10251754B2
A medical device for creating an artificial knee joint or an artificial cruciate ligament in a mammal patient, the medical device comprising a transversal member adapted to be placed through at least three layers of cortical bone of the distal portion of the femoral bone, out of totally four cortical layers along a prolongation of the transversal member. The transversal member is adapted to be involved in the artificial knee joint or the artificial cruciate ligament, wherein the transversal member comprises at least one fixation portion adapted to be involved in fixation of the transversal member to at least one of the at least four layers of femoral cortical bone.
US10251751B2
A customized allograft that is bendable and suitable for allo-grafting of an articular joint, including the thumb.
US10251730B2
The present invention provides an implant body formed from metal or ceramics as a raw material, the implant body including a modified surface, provided with a plurality of projections and a plurality of crevasse-like nanoscale grooves, by which focal adhesion formation, penetration of collagen fibers, arrangement of the collagen fibers in a single direction to thereby adhere to connective tissue, and soft tissue sealablity are possible. According to such a surface modification, focal adhesion formation and the arrangement of the cell cytoskeleton can be enhanced, and penetration of collagen fibers into the surface internal portion is possible.
US10251727B2
A method and system for producing a dental implant surgical guide is disclosed. A patient-specific virtual model is generated using image data specific to a patient and virtual dental implants. The virtual model aligns the image data with the virtual dental implants using modeling software. A virtual mold is generated from the virtual model, and a physical mold is generated from the virtual mold. The physical mold is covered with a thermoplastic sheet via a thermoforming process. Excess thermoplastic material is trimmed off after the thermoforming process to produce a thermoformed piece. Metal tubes corresponding to each the virtual dental implants are placed onto the physical mold denoting the position, trajectory, and depth of the one or more virtual dental implants. A dental implant surgical guide that contains the thermoformed piece with the one or more tubes is produced.
US10251726B2
A method for generating a dental preparation guide configured for validating the preparation of at least one tooth for a dental restoration. A tooth is virtually removed from a digital 3D representation of the patient's pre-prepared set of teeth to form a digital 3D representation of a remaining set of teeth. A virtual target dental restoration expressing a target shape of the dental restoration is obtained and a virtual validation surface for the dental preparation guide is created based on the virtual target dental restoration, where the validation surface is such that the preparation of the tooth can be validated by the dental preparation guide. A virtual preparation guide surface is created by combining the virtual validation surface and part of the surface of the digital 3D representation of the remaining set of teeth.
US10251716B2
Robotic surgical systems are provided for control of an end effector in response to actuation of a user interface device based upon different control states. In each control state, selected movement directions of the user interface device are either coupled to or decoupled from corresponding movements directions of the end effector. Decoupled movement directions can be recoupled by positioning the user interface device within a range of where the user interface device and the end effector were decoupled. To assist with such recoupling, a graphical image estimating a position of the end effector that would be achieved, based upon a current position of the user interface device, if the decoupled movement direction was recoupled can be overlaid upon a current position of the end effector.
US10251713B2
A robotized surgery system (10) comprises at least one robot arm (11) which acts under the control of a control console (12) intended for the surgeon. The console (12) comprises an eye tracking system (21) for detecting the direction of the surgeon's gaze and for entering commands depending on the directions of the gaze detected. The console (22) comprises advantageously a screen (23) with at least one zone (23) for viewing the operating field and, among the commands which can be performed depending on the gaze directions, there is advantageously an automatic command for enabling or disabling the movement of the robot arm (11) when a gaze direction which falls within or outside of said zone (23) of the screen is detected.
US10251708B2
A method of generating a 4D model includes capturing imagery of a catheter and a vessel as the catheter is directed through the vessel to a location of interest, wherein the catheter is disposed on a guidewire, constructing a 3D time varying reference curve describing a trajectory of the guidewire, and constructing a time varying 3D model of the artery using the reference curve.
US10251707B2
A method of generating a computerized bone model representative of at least a portion of a patient bone in a pre-degenerated state. The method includes: generating at least one image of the patient bone in a degenerated state; identifying a reference portion associated with a generally non-degenerated portion of the patient bone; identifying a degenerated portion associated with a generally degenerated portion of the patient bone; and using information from at least one image associated with the reference portion to modify at least one aspect associated with at least one image associated the generally degenerated portion. The method may further include employing the computerized bone model representative of the at least a portion of the patient bone in the pre-degenerated state in defining manufacturing instructions for the manufacture of a customized arthroplasty jig.
US10251703B2
Treatment systems are provided, which comprise a treatment element applying a treatment to a tissue, a stimulation element optically stimulating nerves in the tissue, a sensing unit sensing an electrical signal produced by nerves in the tissue in response to the optical stimulation, and a control unit controlling the application of the treatment according to the sensed signal. The systems and methods are used to avoid damaging nerves by sensing them during operation and immediately before local treatment application and preventing energy emission when the treatment tool is too close to specified nerves. Additional electric stimulation may be provided to enable avoidance of nerve damages on a larger scale, the treatment may be applied by a cold laser, and the control unit may control the treatment in realtime and in a closed loop and immediate prevent further treatment upon sensing optically stimulated nerves.
US10251702B2
In some embodiments, the instant invention provides for a system that includes at least the following components: (i) an Alexandrite laser pumping subsystem; where the Alexandrite laser pumping subsystem is configured to: 1) produce wavelengths between 700 and 820 nm, and 2) produce a pump pulse having: i) a duration between 1 to 10 milliseconds, and ii) an energy measuring up to 100 Joules; where the Alexandrite laser pumping subsystem includes: 1) an optical fiber, and 2) a Lens system, (ii) a Thulium doped Yttrium Aluminum Garnet (Tm:YAG) laser subsystem; where the Tm:YAG laser subsystem includes: 1) a Tm:YAG gain medium, 2) a rod heat sink, and 3) at least one cooling device, (iii) a wavelength selecting device, where the wavelength selecting device is configured to deliver a wavelength between 1.75 microns to 2.1 microns; and where the system is configured to produce a high energy conversion efficiency.
US10251700B2
Cardiac tissue ablation catheters including an inflatable and flexible toroidal or spherically shaped balloon disposed at a distal region of an elongate member, a flexible circuit carried by an outer surface of the balloon, the flexible circuit including, a plurality of flexible branches conforming to the radially outer surface of the balloon, each of the plurality of flexible branches including a substrate, a conductive trace carried by the substrate, and an ablation electrode carried by the substrate, the ablation electrode in electrical communication with the conductive trace, and an elongate shaft comprising a guidewire lumen extending in the elongate member and extending from a proximal region of the inflatable balloon to distal region of the inflatable balloon and being disposed within the inflatable balloon, wherein a distal region of the elongate shaft is secured directly or indirectly to the distal region of the inflatable balloon.
US10251698B2
An ablation catheter includes a control handle and a catheter sheath removably connectable to the control handle, the catheter sheath defining a fluid lumen and having a plurality of perforations proximal the distal end of the catheter sheath. The ablation catheter further includes a shape-imparting element inserted into the fluid lumen of the catheter sheath and removably connectable to the control handle. The shape-imparting element is connectable to an RF energy source so that, in use, the shape-imparting elements act as an electrode charging fluid into the fluid lumen to be expelled through the plurality of perforations on the catheter sheath.
US10251695B2
An electrosurgical device for recognizing tissue by means of spectral analysis of the light generated at an electrode. An acoustic or optical indicator device displays the tissue type permanently or when detecting certain tissue. Indicators, in particular optical indicators, are arranged in the application field of view, so as to support the user in response to making an incision.
US10251689B2
A placement tool for positioning a multipart cannulated screw assembly to fixate first and second bone elements. The placement tool includes a stem and a head carried on the stem. The head has an outer shank engagement provision that engages the proximal end of an outer shank of a bone screw assembly and permits selective rotation of the outer shank. The head also has an inner shank engagement provision that engages the proximal end of an inner shank of the bone screw assembly and permits selective rotation of the inner shank. The inner shank and outer shank engagement provisions are connectable to one another such that the inner shank and outer shank engagement provisions rotate together.
US10251680B2
An implantable device may include a barrel, the barrel having an upper portion and a lower portion. The implantable device may further include an actuator assembly disposed in the barrel, and a central screw that extends from a rear ramped actuator through a front ramped actuator. The implantable device may further include a first plate having multiple projections extending from one side of the first plate. The implantable device may further include a second plate having multiple projections extending from one side of the second plate, the second plate configured to be received on the central screw. The barrel may be configured to transition from a collapsed form having a first height to an expanded form having a second height and wherein the second height is greater than the first height.
US10251677B2
The invention relates to a uniplanar bone anchoring element (10) comprising an anchoring screw (12) with a bone thread (14) and a screw head (18), which is flattened on at least one side (17); a receiving element (20) that has a through-bore which tapers in a lower region (21) and in which the anchoring screw (12) can be received; and two limbs (25, 26) which extend upwards and which comprise a threaded profile (27) in an upper region, said threaded profile being designed for screwing on a securing screw. The receiving element (20) has an inner groove (24) which partly runs at least in the circumferential direction in the seat region of the anchoring screw head (18). The bone anchoring element also comprises a bearing element (40) for inserting into the inner groove (24) of the receiving element (20). The bearing element (40) is partly flattened on at least one side (47), and the groove and the bearing element are designed in a complementary manner such that the bearing element is positioned in the groove in a specified position.
US10251673B2
A medical device insertion system, and a method of using the system, to mate trocars inside a patient during a medical procedure, the system including a first trocar having a first end to insert into a patient, and a second end at which a first user control is provided, and a second trocar having a first end to insert into a patient, and a second end at which a second user control is provided, wherein the respective first ends of the first and second trocars are formed so as to mate to one another inside the patient to form a continuous path between the respective second ends.
US10251669B2
A system and method for holding a cutting tool at a predetermined distance from a defined cutting surface to prepare a tissue flap of substantially uniform thickness for optimal viability. A tissue holder plate having a vacuum chamber is provided to stabilize the tissue mass, and a cutting tool holder and guide plate restrict the movement of the cutting tool with respect to the tissue holder plate.
US10251656B2
Surgical techniques, instruments and systems for bone fusions and repairs (for example, phalangeal fusion) which allow alignment of small bones (for example, phalanges) without the use of guidewire and cannulated instrumentation such as, for example, drills and drivers, and cannulated screws. A drill/driver hybrid instrument (a combined drill/driver device) may be used in fusion of two small bones (for example, in interphalangeal fusion). One end of the hybrid instrument is provided with a plurality of flutes so that the instrument can be used as a drill to remove bone. The other end is shaped to mate with a device to be inserted intraarticularly (for example, interphalangeally), acting as a driver for that device.
US10251650B2
Described here are closure devices and methods for ligating tissue, such as the left atrial appendage. The closure devices may comprise a snare loop assembly comprising a snare and a suture loop releasably attached thereto. The snare may be releasable from an elongate body of the closure device. In some instances, the closure device may comprise one or more markers to allow a user to determine whether the snare loop assembly is twisted.
US10251649B2
A buttress applier cartridge includes a housing, a platform, a buttress assembly, and a data communication feature. The housing defines a gap that is configured to receive a portion of an end effector of a surgical stapler. A portion of the platform is exposed in the gap defined by the housing. The buttress assembly is positioned on the platform. The buttress assembly is exposed in the gap defined by the housing. The data communication feature is configured to provide communication of data relating to the cartridge. The data communication feature may communicate with a complementary data communication feature of the surgical stapler.
US10251642B2
Surgical instruments and their methods of use are disclosed. In some embodiments, the surgical instrument may include a handle and an elongated shaft assembly extending distally from the handle. The surgical instrument may also include a fastener deployment system for deploying fasteners from the elongated shaft assembly including a reciprocating driveshaft disposed within the elongated shaft assembly. The driveshaft may include an internal channel and at least one guide surface shaped and arranged to maintain an orientation of at least one fastener in the channel of the driveshaft. In other embodiments, the fastener deployment system may include a follower disposed within the elongated shaft assembly for displacing one or more fasteners within the elongated shaft assembly towards a distal fastener deployment position.
US10251640B2
A device to assist in securing a holding a portion of a suture during an intra-abdominal suturing procedure, the device including an elongated tubular body, a handle, an inner member element, and a push button. The inner member element may include at least one grasping element that expands as the at least one grasping element is extended beyond a distal end of the elongated tubular. The device may include a proximal spring disposed within the push button and abutting against a proximal end of the inner member element to allow the at least one grasping element to retract into the elongated tubular body in a proximal direction.
US10251636B2
Devices and methods for cleaning a surgical device, and or end effectors associated with the device, are provided. In one exemplary embodiment, a surgical device includes a housing, a plurality of shafts extending distally from the housing, a port disposed at a proximal end of the shafts to form a proximal compartment and an end effector receiver disposed at a distal end of the shafts to form a distal compartment. A fluid and/or a vacuum source can be supplied at the port, through the proximal compartment and shafts, and to the distal compartment. The supplied fluid or vacuum source can be effective to remove fluid and/or tissue from the distal compartment. A plurality of seals can be provided on an outer-most shaft in the compartments to seal fluid from the compartments from entering a housing and/or an outside environment. Other devices and exemplary methods are also provided.
US10251635B2
The invention relates in some aspects to a device for use in anchoring an implant, including anchors, sutures, implants, clips, tools, lassos, and methods of anchoring among other methods. Anchors as disclosed herein could be utilized to secure a coaptation assistance device, an annuloplasty ring, an artificial valve, cardiac patch, sensor, pacemaker, or other implants. The implant could be a mitral valve ring or artificial mitral valve in some embodiments.
US10251630B2
An excision device including a guide rod assembly and methods of operating the same are disclosed. An excision device includes a housing coupled to a coring cannula, a stylet with a blade, and a guide rod assembly. A hollow central passageway extends through the center of the excision device. The guide rod assembly is coupled to the housing and includes a guide element having first and second ends and comprised of a guide rod and a locking member. The guide rod is slidably disposed within the central passageway. The locking member is fixed to the second end of the guide rod. The guide rod assembly further includes an anchor stabilization rod slidably disposed within the central passageway. A coupling device, a first portion of which is fixed to the guide rod and a second portion fixed to the anchor stabilization rod, couples the anchor stabilization rod to the guide rod.
US10251627B2
The present invention relates to an ultrasound elastography system (10) for providing an elastography measurement result of an anatomical site (32) a corresponding method. The system (10) is configured to visualize a suitability for shear wave elastography of the region of interest (33) to the user within the ultrasound image (52) and/or to recommend an elastography acquisition plane (48, 50) for conducting shear wave elastography to the user. By this, proper selection of a location for an elastography measurement may be supported.
US10251624B2
A delta-sigma beamformer includes a beamsummer and a plurality of delta-sigma modules. Each of the delta sigma modules includes a delta-sigma modulator configured to receive analog ultrasound signals from one or more transducer elements and output a delay line including a plurality of samples based on the analog ultrasound signals. Each delta-sigma modulator includes a comb filter connected to the delta-sigma modulator and configured to output a difference between two of the plurality of samples in the delay line. Each delta-sigma modulator includes an accumulator module. Each accumulator module includes an accumulator connected to the comb filter. Each accumulator module is configured to integrate signals received from the comb filter during a non-delay-expansion period and transmit the integrated signals to the beamsummer during the non-delay-expansion period. Each accumulator module is configured to output a zero to the beamsummer during a delay-expansion period.
US10251623B2
A support apparatus of an ultrasound probe, a handsfree ultrasound probe including the support apparatus, and a method of operating the support apparatus. The support apparatus includes: a housing including an accommodation unit capable of accommodating an ultrasound probe and an adhesion unit capable of contacting a target object; and a first control unit for controlling an adhesive force with respect to the target object of the adhesion unit according to whether a user touches at least one of the ultrasound probe and the housing.
US10251608B2
A system (10) for detecting and displaying baropostural parameters comprises a platform (11) with a footplate (15) intended to accommodate a person standing on it and provided with sensors for detecting the pressure distribution of the imprint of the two feet on the footplate. An electronic acquisition device (32) is connected to the sensors for digital acquisition of the pressure distribution in order to create a map of the pressure points of the feet on the footplate. Calculation means (33a) are designed to calculate, for each foot and for both feet on the footplate, the geometric centers (52, 53, 54) and the barycenters (55, 56, 57) of the map of the pressures and display means (33b) display on a screen (31) a graphical representation of the imprints of the two feet on the footplate together with the corresponding geometric centers (52, 53, 54) and barycenters (55, 56, 57) calculated by the calculation means. The footplate may have a rear part (15) which can be raised for simulating shoe heels underneath the heels. Front and/or lateral telecameras (19, 20) may be provided in order to provide further postural data.
US10251607B2
A physiological signal measurement apparatus includes a battery cover covering an area where a battery of a terminal device is detachably attached, a sensor unit detecting a physiological signal, the sensor unit being included in the battery cover, and a control unit controlling the sensor unit to detect the physiological signal, wherein the physiological signal measurement apparatus is detachably attached to the terminal device as the battery cover is detachably attached to the terminal device.
US10251602B2
A health monitoring system, and methods of use and manufacture thereof are disclosed. The health monitoring system may include a computing system and a diagnostic test coupled to a diaper. The diagnostic test may include one or more sensors configured to produce a visual indication of one or more analytes contained in a sample produced by a subject. The diagnostic test may include a machine-readable code. The computing system may be configured to read the machine-readable code to allow an application running on the computing system to automatically perform at least one task related to a production of a data point based on the visual indication. The health monitoring system may aid in identifying a potential abnormal health condition of the subject by providing automatic longitudinal analysis of analytes contained in samples produced by the subject over a period of time.
US10251600B2
A surgical system used to determine if a vessel is within a region proximate to a working end of a surgical instrument includes at least one light emitter disposed at the working end of the surgical instrument, the at least one light emitter adapted to emit light of at least two different wavelengths. The system also includes at least one light sensor disposed at the working end of the surgical instrument opposite the at least one light emitter, the at least one light sensor adapted to detect light at the at least two different wavelengths. The system further includes a controller coupled to the at least one light sensor and adapted to determine a ratio of the light absorbed at the least two different wavelengths, and to indicate if an artifact within a region proximate to the working end of the surgical instrument is a vessel based on the ratio.
US10251593B2
A method and system for monitoring and preventing a patient from developing pressure ulcers, comprising (1) a sensing unit, which includes a pressure sensor, attachable to a body part of a patient and having a unique identifier, for detecting pressure exerted by a supporting surface and outputting pressure data indicative of pressure as a function of time; and a wireless transceiver for transmitting the pressure data and/or the unique identifier; (2) a controller unit configured for receiving the pressure data and the unique identifier, associating the unique identifier with the body part of the patient, and for transmitting the pressure data and the unique identifier; and (3) a central server device configured for (i) receiving the unique identifier and the pressure data from the controller unit; (ii) determining whether the pressure data exceeds a predetermined value associated with the body part of the patient; and (iii) transmitting to the controller unit a determination that the pressure data exceeded the predetermined value, the controller unit outputting a signal indicative of the determination.
US10251592B2
Systems and methods for noninvasively determining the function capacity of the kidney are provided. In the methods, first contrast agent is injected into the vasculature of a subject. The contrast agent is to be bound with functioning glomeruli of the kidney of the subject. Then, the kidney is imaged with a magnetic resonance imaging (MRI) system to acquire MRI images of the kidney. In the images, signal magnitudes or phases of voxels of regions bound with the contrast agent are different from signal magnitudes or phases of voxels of regions not bound with the contrast agent. Afterwards, the function capacity of the kidney is determined using the MRI images. Lastly, a report of the function capacity of the kidney is generated.
US10251588B2
Disclosed are methods, apparatuses, etc. for glucose sensor signal reliability analysis.
US10251580B2
This disclosure relates to a flexible circuit for insertion into a pill capsule. The flexible circuit has a first portion having an electrical contact to electrically connect with a battery, a second portion having an electrical contact to electrically connect with the battery, a first arm separating the first portion and second portion, a third portion comprising a first antenna, a second arm separating the first portion and third portion, a fourth portion comprising a second antenna, a third arm separating the first portion and fourth portion, a third arm separating the first portion and fourth portion, and a fifth portion comprising a third antenna. The first portion, second portion, and first arm form a first receptacle to receive a battery. The third portion, fourth portion, and fifth portion form a second receptacle to receive a cube ferrite core.
US10251570B2
A wearable electronic device comprising a wearable component and a device body is provided. The device body is connected to the wearable component. The device body includes a processor, a main light source, an auxiliary light source and a light sensor. The light sensor is electrically connected to the processor. An absorptivity to main rays from the main light source by human blood is more than twice of the absorptivity to auxiliary rays from the auxiliary light source. The light sensor detects intensities of the main rays and the auxiliary rays reflected by the human body. The processor corrects an error of the intensity of the main rays received by the light sensor according to the intensity of the auxiliary rays received by the light sensor to obtain a heart rate. A method for detecting a heart rate is also provided.
US10251569B2
Intravascular devices, systems, and methods are disclosed. In some embodiments, a method of assembling an intravascular device is provided that includes positioning a first tubular member around a plurality of conductors and a core member; advancing a first of the plurality of conductors through an opening of the first tubular member; positioning a first conductive member around the first tubular member; and electrically coupling the first of the plurality of conductors to the first conductive member. In some embodiments, an intravascular device is provided that includes an insulating member positioned around a plurality of conductors and a core member and a conductive member positioned around the insulating member, wherein at least one of the plurality of conductors extends through an opening in the insulating member and is electrically coupled to the first conductive member.
US10251565B2
An integrated vitals device capable of acquiring multiple data streams, allowing for comprehensive measurement of whole health status using a single, compact device. This allows for simplification of traditional healthcare delivery where multiple devices are required for acquisition of vital signs. A sensor stack up, occupying the approximate physical footprint and volume allows this approach to be possible. This application describes how these simultaneous vitals data streams can be acquired using an integrated device with small mass and volume.
US10251562B2
Discussed herein are an apparatus and a corresponding method for classifying a murmur detected in a heart signal as a Still's murmur. Circuitry included in the apparatus segments a heart signal to detect a first lobe (S1) and a second lobe (S2) of the heart signal. Further, the circuitry computes a spectral width of an extracted feature of the heart signal that lies in a portion of a time interval between the S1 lobe and the S2 lobe based on an estimated power spectral density. Additionally, a peak frequency of the extracted feature of the heart signal and a shape of an envelope of the extracted feature of the heart signal are computed. The extracted feature of the heart signal is classified as the Still's murmur based on the spectral width, the peak frequency, the shape of the envelop, and additional murmur discriminant features.
US10251560B2
An image forming apparatus has acoustic transducers; and an image processing unit which calculates intensity of acoustic waves irradiated from regions inside a subject respectively by processing received signals, which are output from the acoustic transducers, by a Fourier-domain method. The image processing unit includes: a coefficient memory which stores coefficients computed in advance, the coefficient being a value determined only by a position of the acoustic transducer, position of the region and a time of receipt of the acoustic wave; a multiplier unit which multiplies the received signal of the acoustic transducer by the corresponding coefficient; and a voxel memory which accumulates multiplication results of the multiplier unit for each region.
US10251549B2
En face views of OCT volumes provide important and complementing visualizations of the retina and optic nerve head investigating biomarkers of diseases affecting the retina. We demonstrate the combination of real time processing of OCT volumetric data for axial tracking. In combination with a Controllable Optical Element (COE), this invention demonstrates acquisition, real time tracking, automated focus on depth resolved en face layers extracted from a volume, and focus stacked OCT volumes with high resolution throughout an extended depth range.
US10251544B2
Various embodiments relate to systems and methods for performing eye examinations using an HMD that is able to present an image to each eye individually and then to both eyes simultaneously. Because the HMD, rather than a patient, controls conditions (e.g., glare, brightness) during the examination, test results are more likely to be accurate and reliable. In some embodiments, the HMD employs voice recognition to replicate the conversational exchange that would typically occur between the patient and the ophthalmologist or optometrist. The HMD may also be configured to change the visual environment experienced by the patient during testing. Further yet, the HMD, or another distinct computing system, may be configured to identify abnormal test results in real-time and, in some embodiments, the examination is modified accordingly. For example, tests scheduled to be performed during the examination can be modified or removed and new tests can be added.
US10251533B2
The outer tube includes two insertion holes which are formed in a cross-sectional D-shape via a partition wall provided in the central part in a cross-section vertical to respective axial directions of the insertion holes. A slit of a valve body located in the insertion hole is disposed along reference line passing through centers of respective arcs of the insertion holes as seen from the axial directions of the insertion holes. Therefore, two leaflets of the slit abut on an arc edge of the insertion hole and a D-shaped cut part of the partition wall respectively when the insertion part of the treatment tool is internally fitted, and they are deformed into the same shape. Since there is no difference in stress applied to two leaflets, it is possible to secure the airtightness by the slit over a long period of time.
US10251531B2
The present disclosure relates to a control device, a medical device, and a medical device system that enable to provide a user who tries to connect the medical device to the control device with user support information including a result of compatibility determination between the devices.A control device according to one aspect of the present disclosure is provided with a connector joint to which a connector unit provided on a cable extending from a medical device is connected, a communication unit that performs radio communication with the connector unit by proximity radio communication, and a notification unit that notifies a user of user support information based on information from the medical device received by the communication unit. The present disclosure is applicable to an endoscopic surgical system, for example.
US10251525B2
A method for forming compression-bonding portions in a continuous body including a fiber bundle while conveying the continuous body includes: rotating a rotator to convey the continuous body; compressing a target part of each of the compression-bonding portions in the continuous body using a first compression-bonding apparatus and the rotator to form the compression-bonding portions of a first stage; and further compressing each of the compression-bonding portions of the first stage using a second compression-bonding apparatus and the rotator to form the compression-bonding portions of a second stage. At least one of the compression-bonding portions is positioned between the first compression-bonding apparatus and the second compression-bonding apparatus in the direction of rotation of the rotator when the second compression-bonding apparatus compresses the compression-bonding portion of the first stage.
US10251522B2
A riding floor cleaning machine having an intelligent system including a main frame sub-assembly, a steering and drive wheel sub-assembly, a solution tank sub-assembly, a recovery tank sub-assembly, a recovery tank cover sub-assembly, a control panel sub-assembly, a main controller sub-assembly, a seat and detergent system sub-assembly, a battery sub-assembly, a scrub head sub-assembly, a scrub head lift sub-assembly, a squeegee sub-assembly, a solution and detergent sub-assembly, and an intelligent system associated with at least one of the above-identified sub-assemblies, wherein the intelligent system selectively gathers, obtains, monitors, stores, records, and/or analyzes data associated with components of the riding floor cleaning machine, and controllably communicates and/or disseminates such data with another system and/or user.
US10251518B2
A dispensing system for dispensing cleaning product for hand sanitization comprises a cartridge having an internal reservoir for containing hand sanitization product, a nozzle configured in one of a plurality of key shapes, and a dispenser having a receptacle opening adapted to receive and engage the nozzle of the cartridge when the receptacle opening is configured in one of a plurality of key shapes corresponding to the key shape of the nozzle, the dispenser having a fluid communication passage for dispensing fluid for hand washing, whereby only cartridges and dispensers which have matched key shapes will engage each other for operative discharge of the hand wash cleaning product. The system includes a valve insert member which prevents leakage of fluid unless the nozzle key matches the receptacle opening. The valve insert member is in the form of a cup shaped member of elastomeric material, said member having a curved top having at least one slit having two slit edges, said slit defining a valve which is normally closed when the two slit edges are in mutual contact, but which slit edges separate when the curved top is penetrated, to thereby open the valve. Two slits can be provided in a cross-pattern.
US10251516B2
A container system for separately storing and mixing two or more substances. The container system comprises a mixing container having a main container that stores one or more first substances. The main container has a first upper opening. The container system also includes a storage repository coupled to main container, and which stores one or more second substances. The storage repository includes a lip defining a second upper opening, which has an outside diameter smaller than the diameter of the first upper opening. Additionally, the container system includes a mixing blade having an outside diameter smaller than the diameter of the first upper opening. The mixing blade also has a plurality of openings. The container system includes a releasable liner placed over the storage repository's lip, and the storage repository's lip forms a seal with a lower surface of the releasable liner.
US10251506B1
An apparatus used in a cooking pot and holding up to thirteen small-to-large chicken eggs for the purpose of steaming the eggs until cooked. The apparatus has a bottom surface with six lower egg supports and one center egg support. Six additional upper egg supports are located radially and alternatingly between six perimeter wall sections. The bottom surface is elevated on legs that allow a small volume of water to be placed under it and heated to steam the eggs. The perimeter walls extend upwardly from the bottom surface above eggs seated on the lower egg supports, each wall section having a beginning slicing guide slot aligned with the centers of seated eggs. Finishing slicing guide slots also extend through the center egg support and each of the lower egg supports to allow a slicing device inserted into the vertically-extending slicing guide slots to cut peeled eggs in half.
US10251504B1
A Christmas tree disposal casing, having an upper end and a lower end, and a first panel and a second panel that each have an inner edge, an outer edge, an upper edge, and a lower edge. The casing has a flat configuration and also has a sleeve configuration for encasing a tree therein when the first panel is joined to the second panel at or near their outer edges. An expansion panel is affixed near and extends between the inner edges. The inner edges are selectively joined directly together along an expansion seam. When the expansion seam is opened, the expansion panel provides additional circumference to the casing for holding larger trees. The outer edge of the first panel is selectively joined to a secondary zipper edge on the second panel, located inwardly of the outer edge of the second panel, to reduce the circumference of the casing.
US10251494B1
A retail merchandise tray is provided. The retail merchandise tray includes a pair of load bearing members, a front stop mounted to the load bearing members, a wire support structure removably attached to the front stop and load bearing members, a pusher that slides along the wire support structure, and a pair of movable divider assemblies.
US10251492B2
Sleeping accessories such as mattress pads, mattress topper covers, and sheet savers are disclosed herein comprising integrated padded mesh material. Integrated padded mesh material, when used in the sleeping accessories, results in improved air flow for the user, which can reduce complications during sleep such as sudden infant death syndrome. The material may have one or multiple layers, and may include a moisture wicking fabric, allergy-blocking fabric, or water resistant fabric. Certain layers are padded to provide more comfort for the user and in some embodiments, the padded layer may be sloped to assist with reflux.
US10251491B2
In order to provide a seat having enhanced apparent quality by covering a connecting part, the present invention is a seat 1 wherein a coating cover 40 for coating a first fastening part 30 is provided to an end of a surface cover 4.
US10251487B2
A seat assembly having a seat back and a thoracic support mechanism. The thoracic support mechanism may have a flex plate that may be movably disposed on a support member of the seat back frame. A first actuator may flex the flex plate. A second actuator may actuate the flex plate along the support member.
US10251485B2
Disclosed herein is an easily to assemble seating furniture of the present disclosure includes a back assembly, side assemblies, a front assembly, legs, and a seating assembly. The legs are used to secure the back assembly and the front assembly to the side assemblies.
US10251484B2
Furniture is described having an extendable footrest. The footrest has a main panel and a flipper panel. In an extended position of the footrest, the top surfaces of the panels are approximately horizontal and co-planar, the main panel being proximate to a seat portion of the furniture. In a retracted position of the footrest, the top surface of the main panel is approximately vertical and the top surface of the flipper panel is approximately horizontal and facing in a downward direction. The footrest projects substantially 20″ or more from the front of the seat portion in the extended position, and substantially 7″ or less is provided between the floor and the apparent bottom edge of the footrest when retracted.
US10251481B2
A retraction device includes an entrainment member to be releasably coupled to the movable furniture part, and a spring device for applying a force to the entrainment member in a direction opposite to an extension direction of the entrainment member. The spring device can be tensioned in the extension direction of the entrainment member by a spring holder separate from the entrainment member. A coupling device can couple a movement between the entrainment member and the spring holder, and can vary the distance of a fastening location of the spring device relative to the entrainment member as the entrainment member extends in the extension direction. The coupling device includes a control element having a longitudinal axis extending in the extension direction. To vary the distance between the fastening location and the entrainment member, the control element rotates about its longitudinal axis when the entrainment member is extended in the extension direction.
US10251472B1
An infinity brush has a flaccid belt configured to define a lemniscate. A plurality of work-contacting segments protrude from and are carried by the flaccid belt. A mechanical drive rotates the flaccid belt. Various embodiments of the flaccid belt include a single lemniscate, a plurality of lemniscates, and various simulated lemniscates. In one embodiment, the infinity brush bristle includes non-cylindrical brush bristles with a longitudinal shaft having at least one diameter transition, while other bristles comprise beads of various oval, circular, and cylindrical geometries.
US10251464B2
The backpack has a main body that unfolds to lie flat providing ready access to the contents of the pack and various separate accessory pouches carried within the main body of the pack. The main body of the backpack is formed by a flat back panel, a pair of flat side panels and a top panel. The side panels and the top panel are integrally connected to the back panel and fold together to fashion the main body of the backpack in a folded orientation and unfold to lie flat side-by-side in an unfolded orientation. The panels are adapted to selectively support a variety of detachable accessory pouches. They provide compartment for stowing items to be carried in the backpack.
US10251463B2
In order to appropriately assist with the application of makeup, including technical improvements in makeup techniques, a makeup application assistance device includes: an image acquisition unit that acquires an image obtained by photographing a face to which makeup has been applied; an applied makeup technique acquisition unit that acquires applied makeup techniques, which are makeup application methods, from the image; a makeup technique evaluation unit that evaluates the applied makeup techniques by comparing the applied makeup techniques with reference makeup techniques that are to be referenced by a user who applied the makeup; and an evaluation presentation unit that presents the results of the evaluation to the user.
US10251459B2
According to an aspect of the present invention, there is provided an air vibration apparatus which is coupled to a blowing port of a hair dryer to vibrate air, the air vibration apparatus including: a pipe-shaped adapter which is coupled to a blowing port and into which air flows; a rotating unit which includes a pipe-shaped rotating body which is rotatably coupled to the inside of the adapter, into which the air flows from one end, and which rotates by means of the air, and a control bar coupled to the rotating body to be extended from the rotating body; and a rotating blade unit which is hinge-coupled to an end portion of the adapter by means of a hinge portion and comes in contact with the control bar to vibrate based on the hinge portion according to the rotation of the rotating body.
US10251457B2
Provided is a luggage piece that can be coupled to a second luggage piece to be transported together as a joined unit, and a luggage system including such luggage pieces. The luggage piece includes a housing for storing items to be transported therein, and a retractable handle provided to the housing. A plurality of rollers coupled to the housing allow the luggage piece to be rolled, and include at least two in-line rollers having a generally-fixed rolling direction. The second luggage piece includes two or more adjustable rollers having a variable rolling direction. A plurality of tethers couple the luggage piece and the second luggage piece together to form a joined unit that can be steered through adjustment of the rolling direction of the adjustable rollers.
US10251452B2
Articles of footwear may include selectively engageable traction elements that engage with a surface or the ground during certain activities and do not engage with the surface or the ground during other activities. The selectively engageable traction elements are caused to engage with the ground or surface when a portion of the footwear is flexed. When the footwear is in its unflexed position, the selectively engageable traction elements may not engage with the ground or surface. Selectively engageable traction elements may be desired or may be useful during particular, targeted movements such as sharp turns, pivoting, sudden or abrupt starting and stopping motions, and the like and in changing environmental conditions, such as on various surfaces having different characteristics. Wearers of such footwear may benefit from the extra traction provided by the selectively engageable traction elements when performing the targeted movements and/or when wearing the footwear on surfaces with varying conditions.
US10251449B2
An article of footwear may have a sole structure and an upper that includes a foundation element, a tensile strand, and a securing strand. The tensile strand is located adjacent to an exterior surface of the foundation element and substantially parallel to the exterior surface for a distance of at least five centimeters. The securing strand joins or secures the tensile strand to the foundation element. Although the thicknesses may vary, a thickness of the tensile strand may be at least three times the thickness of the securing strand. In some configurations, a backing strand may also assist with joining the securing strand to the foundation element.
US10251445B2
An improved article of footwear includes a midsole, an upper, and a support member. The midsole of the footwear contains a forefoot region, a heel region, a middle region. The midsole contains a medial recess and a lateral recess in the sidewall, and a central opening in the bottom surface, where the recesses and the central opening are in fluid communication with one another. The upper of the footwear is disposed on the midsole, but the bottom surface of the upper that is proximate to the central opening, the medial recess, and the lateral recess of the midsole is exposed. A support member is disposed on the bottom surface of the upper proximate to the central opening of the midsole. The support member is configured to extend from the bottom surface of the upper through the central opening of the midsole.
US10251432B2
The present invention is directed to a golf shirt with two laterally-opposed textile bands affixed thereto that are less stretchable than a textile used to construct the torso portion and the shoulder portion of the shirt. A first end of each band is adhered to a skirt of the collar portion, and a second end is adhered to a free end of the shirt. One side of the length of the pair of bands is adhered to the shirt at each point between the first and second end. When the shirt is worn by a person, and the person addresses a golf ball (e.g., extends his arms in front of his body and/or partially clasps his hands together around a golf club), the textile used to construct the bands pulls the sleeve portion away from the wearer and/or decreases a movement associated with the sleeve portion.
US10251427B2
A multi-part aerosol-generating assembly system has a mouth end and a distal end, and includes a first part having a housing and a power supply disposed in the housing. The system also includes a second part releasably connectable with the first part. The second part includes a heating element and a liquid transfer element. The heating element is operably coupled to the power supply when the second part is connected with the first part. The system further includes a third part releasably connectable with the second part. The third part includes a reservoir containing a liquid aerosol generating substrate. The liquid aerosol generating substrate is in fluid communication with the liquid transfer element when the third part is connected with the second part. The system further includes a cover disposable over the third part. The cover is releasably securable in a position relative to the third part.
US10251415B2
Some embodiments relate to nutritional supplements comprising rice protein isolate. Some embodiments of the nutritional supplement comprise less than about 90 mg of leucine per gram of rice protein isolate and less than about 50 mg of lysine per gram of rice protein isolate. Some embodiments pertain to methods of using the nutritional supplements described herein to achieve one or more of weight gain, weight maintenance, growth, muscle growth, muscle maintenance, decreased muscle loss, or improved exercise training results.
US10251408B2
The present invention provides a composition comprising a tea extract or a catechin and a citrus fruit extract or a flavanone or a glycoside thereof.
US10251403B2
A baking pan for baking a tilted cake for producing a whimsical or mad-hatter cake, the pan includes a rim defining a first plane and a tilted bottom defining a second plane, the rim and bottom being interconnected by a sidewall, the two planes intersect at an acute angle and a support for positioning the pan on an oven surface so that the first plane is parallel to the oven surface.
US10251401B2
The present invention is directed to non-aqueous, non-oil liquid compositions comprising Bacillus amyloliquefaciens and a liquid carrier. The present invention is further directed methods of controlling nematodes comprising applying an effective amount of a non-aqueous, non-oil liquid composition comprising Bacillus amyloliquefaciens and a liquid carrier to an area in need of nematode control.
US10251400B2
The present invention relates to pesticidal mixtures comprising as active components the Bacillus strains AP-136, AP-188, APP-218, AP-219, AP-295, AP-209 and/or AP-217 as defined herein and a pesticide II as defined herein and respective agricultural uses thereof.
US10251398B2
Methods of forming antimicrobial resin compositions comprising silver nanoparticles are disclosed, wherein the resin compositions that are generated exhibit lower initial color, reduced color shift upon storage and reduced levels of spontaneous polymerization. Such methods generally comprise: combining a silver-containing material with a self-cure and dual-cure base resin in situ wherein the base resin does not contain a catalytic amine; and adding a catalytic resin to the mixture of the resin and silver-containing material in order to form the final cured resin. Antimicrobial polymeric materials formed by said methods are also disclosed.
US10251387B2
The present invention is a method for enhancing the quality and survival of red blood cells during storage by depleting the red blood cells of both carbon dioxide and oxygen and maintaining 2,3-diphosphoglycerate acid levels.
US10251377B2
The present invention relates to humanisation of antibodies in vivo. The invention provides non-human vertebrates, cells, populations and methods useful for humanising chimaeric antibodies in vivo. Using the present invention it is possible straightforwardly and rapidly to obtain antigen-specific antibodies that are fully human (ie, comprising human variable and constant regions) and have undergone recombination, junctional diversification, affinity maturation and isotype switching in vivo in a non-human vertebrate system. Furthermore, such antibodies are humanised (eg, totally human)—and selected—totally in vivo, and as such the present invention harnesses in vivo filtering for expressibility, affinity and biophysical characteristics in the context of the desired human variable and constant region pairings. This is avoids problems of down-grading antibody characteristics when humanising the constant region of chimaeric antibodies in vitro.
US10251374B2
An animal relocation system and method comprising a perimeter net system a trapping net system, and a flushing device, wherein the flushing device channels the animal through the perimeter net system and into the trapping net.
US10251372B2
This invention relates to a method for promoting growth of young chicken comprising the step; offering feed in a layered manner in subsequent order of pellet-size for adjusting the pellet-size to the size of the young chicken during a whole brooding cycle for the feed being attractive during the whole brooding cycle as perceived by the young chicken.
US10251369B1
The pet carrying case is luggage adapted for use with pets. The pet carrying case is subdivided into a plurality of compartments and a plurality of dispensers that are used to organize the provisions, supplies, and equipment necessary for the care of the domestic animal during travel. The pet carrying case comprises a plurality of compartments, a plurality of dispensers, one or more bungees, a document envelope, a picture frame, a plurality of fasteners, a plurality of D rings, a handle, and a strap. The plurality of fasteners are used to open and close the plurality of compartments. The plurality of dispensers, the one or more bungees, the document envelope, the plurality of fasteners, the plurality of D rings, the handle, and the strap are attached to the exterior of the plurality of compartments. The picture frame is mounted within a compartment selected from the plurality of compartments.
US10251360B1
The present invention relates to a new and distinctive canola, designated G1562823A. Also included are seeds of canola G1562823A, to the plants, or plant parts, of canola G1562823A and to methods for producing a canola plant produced by crossing the canola G1562823A with itself or another canola genotype, and the creation of variants by mutagenesis or transformation of canola G1562823A.
US10251354B2
The invention relates to the soybean variety designated 01064596. Provided by the invention are the seeds, plants and derivatives of the soybean variety 01064596. Also provided by the invention are tissue cultures of the soybean variety 01064596 and the plants regenerated therefrom. Still further provided by the invention are methods for producing soybean plants by crossing the soybean variety 01064596 with itself or another soybean variety and plants produced by such methods.
US10251352B2
The present invention relates to methods for identifying cucumber lines having increased resistance to Downy Mildew, and identification of genetic markers linked to gene(s) conditioning such increased disease resistance. The present invention also relates to methods of breeding cucumber plants from lines having increased Downy Mildew resistance by marker-assisted selection, compositions including nucleic acid probes or primers which are useful for such marker assisted selection, and plants and plant parts produced by such methods.
US10251350B2
Growing system for growing plants, for example vegetables and ornamental plants, includes a container tray (1) which is floatably arranged in a liquid reservoir (14). The container tray (1) is configured to float on nutrient water (6) during use and has at least one opening (4) which is arranged in a tray bottom (2) of the container tray (1) for bringing a growth substrate (11) which is arranged on the container tray (1) into contact with the nutrient water (6). The container tray (1) is a substantially flat container tray (1) which includes an upright tray edge (3), and wherein the at least one opening (4) has an upright opening edge (5) having a height which is such that the growth substrate (11) is situated above a water line of the nutrient water (6) during use.
US10251346B2
Top furling automated retractable greenhouse cover is a retractable cover for a greenhouse that is mounted on top of the greenhouse. Top furling automated retractable greenhouse cover comprises: a spine clamp, a left furling cover assembly, a right furling cover assembly, a hinge pin assembly, and an electrical control box. Left and right furling assemblies each comprise a curtain or cover, a furling rod, a furling motor, and a support arm. Electrical control box sends electronic signals to cause left and right covers or curtains to furl above the greenhouse when retracted and to unfurl down to the ground when extended to cover the greenhouse. The top-mounted design allows efficient use of gravity to apply tension to the furled rolls.
US10251342B2
A chopping module which pulls plants inside the module and chops them into billets, comprising a box-shaped body with three open sides, a front inlet for plants to be chopped, a rear outlet for chopped plants and a lower outlet for residues. Plants are pulled by two crosswise pairs of rollers, after which plants are chopped by a rotating blade assembly and a fixed shearbar, which are aligned parallel to the pulling rollers. Between the pulling rollers, a passageway is formed for the plants to be chopped. After the fixed shearbar, said passageway continues in the form of a slide sloping downwards to the rear outlet. The rotating blade assembly is located above the slide and next to the fixed shearbar.
US10251333B2
A hydraulic control system for controlling the down force on an agricultural implement comprises a hydraulic cylinder containing a movable ram, a source of pressurized fluid coupled to the hydraulic cylinder on a first side of the ram by a first controllable valve, a fluid sump coupled to the hydraulic cylinder on the first side of the ram by a second controllable valve, and an electrical controller coupled to the valves for opening and closing the valves. The valves may be self-latching valves that remain in an open or closed position until moved to the other position in response to a signal from the controller.
US10251328B2
An agricultural tillage implement is provided which includes an electronic sensor assembly supported by a harrow frame and in communication with a hydraulic system. The electronic sensor assembly includes a pivoting arm movable in conjunction with the movement of a first set of smoothing tools and is configured to generate an electrical signal corresponding to the angle of the first set of smoothing tools. The electrical signal is transmitted to a controller and/or an operator in the tractor cab for continuously monitoring the angle of the smoothing tools. The electrical signal is used to allow for the continuous adjustment of the smoothing tools during a tilling session.
US10251324B2
An agricultural device associated with reduced tillage techniques in a field includes a frame and a separator supported by the frame. The separator is configured to form a strip of exposed soil in residual plant matter in the field. A crimping device associated with the separator is configured to at least partially crush stems of residual plant matter while maintaining the strip.
US10257965B1
The electromagnetic shielding of an enclosable building structure is provided by applying a shielded covering to overlay optical openings in the building structure. The shielded covering comprises a metal-coated woven substrate and a shielding coupling. The metal-coated woven substrate has a woven substrate and a metal coating. The woven substrate may be organic and comprise threads of intermingled fibers such as silk fibers. The metal-coated woven substrate may also have a protection feature such as transparent resin, of barriers of glass or transparent polymeric material. The shielded coupling connects the shielded covering to other shielding components of a shielded building structure to preserve shielding continuity over the interface between shielding components.
US10257955B2
A cable backplane system includes cable backplanes each including a tray configured to be coupled to a chassis and a plurality of cable connector assemblies mounted to the tray. The tray has a plate extending between a front and a rear with mounting locations receiving corresponding cable connector assemblies. The trays are oriented parallel to each other with front openings between the fronts of the plates and rear openings between the rears of the plates. Each cable connector assembly has a housing holding contacts terminated to corresponding cables. Each cable connector assembly has a holder mounted to the corresponding mounting location of the plate. The holder is mounted to the plate and removable from the plate through the rear opening at the rear of the plate.
US10257950B2
An electronic device or electronic device assembly may comprise a first portion and a second portion, a first magnet disposed inside the first portion and rotatable about a pivot axis with respect to the first portion, and a second magnet disposed inside the second portion and rotatable about a pivot axis with respect to the second portion. The first and second magnet may be configured to rotate so that the first and second magnets magnetically engage each other when the distance between the first and second magnet is equal to or smaller than a first distance.
US10257946B2
One embodiment provides an electronic device, comprising: a main body component; an adjustable display component comprising a display area, a first shape, a second shape, and an assembly that is partially changeable in shape; and at least one accommodating component; wherein the main body component supports the adjustable display component and the at least one accommodating component. Other aspects are described and claimed.
US10257942B1
A stackable variable height via package includes a substrate having a first surface and terminals thereon. The terminals include a first terminal and a second terminal. Vias are on the terminals, the vias including a first via on the first terminal and a second via on the second terminal. The first via has a height from the first surface of the substrate less than a height of the second via from the first surface of the substrate. The package further includes a package body and via apertures in the package body to expose the vias. Forming the stackable variable height via package with variable height vias readily accommodate stacking of additional packages having different types of terminals, e.g., LGA and BGA type packages, as well as variable degrees of warpage on the stackable variable height via package. Further, the vias are formed with a minimum pitch.
US10257940B2
In an example, a process for reversibly bonding a conformal coating to a dry film solder mask (DFSM) material is disclosed. The process includes applying a first conformal coating material to a DFSM material. The first conformal coating material includes a first functional group, and the DFSM material includes a second functional group that is different from the first functional group. The process also includes reversibly bonding the first conformal coating material to the DFSM material via a chemical reaction of the first functional group and the second functional group.
US10257938B2
The present invention provides a surface-treated copper foil capable of imparting the profile shape of the substrate surface after removal of the copper foil, the profile shape maintaining fine wiring formability and achieving satisfactory adhesion of electroless copper plating coating. The present invention also provides a resin substrate provided with a profile shape of the surface maintaining fine wiring formability and achieving satisfactory adhesion of electroless copper plating coating. The surface-treated copper foil of the present invention is a surface-treated copper foil, wherein a surface-treated layer is formed on a copper foil, and the proportion of the area corresponding to the particles of the surface of the surface-treated layer is 0.1 to 0.85.
US10257932B2
A light source module comprising a semiconductor light source mounted directly to a conducting trace of a multilayer printed circuit board having a core comprising a plurality of core layers electrically and thermally coupled by a plurality of buried vias wherein at least one of the core layers comprises a heat sink plane.
US10257925B2
A method for manufacturing an electronic assembly and electronic assemblies are presented. The method includes obtaining a substrate film for accommodating electronics, providing at least an electrical contact pad to the substrate film, coupling an electrically conductive member to the electrical contact pad, and molding, such as injection molding, a material layer onto the substrate film to embed the elastic electrically conductive member utilizing a mold structure defining a cavity for molding. The elastic electrically conductive member is arranged to extend during the molding from the electrical contact pad through the cavity to be in contact with an element on a different side of the cavity with respect to the electrical contact pad for maintaining at least a part of the elastic electrically conductive member accessible after the molding to provide an electrical connection through the material layer to the electrical contact pad.
US10257907B2
The invention describes an LED lighting module (1) comprising input terminals (13hi, 13lo) for connecting to an input voltage (Uin); an LED load (10) realized to operate at an upper threshold voltage level (Vdim); and a regulation circuit (11, 12) realized to decrease LED current (ILED) through the LED load (10) when the input voltage (Uin) is greater than the upper threshold voltage level (Vdim). The invention further describes an LED lighting arrangement (4) and a method of driving an LED load (10).
US10257896B2
Systems and methods for of dimming generally considered to be non-dimmable with conventional dimmers. An exemplary dimming module accepts a power source for a light source and a dimming signal. The dimming module modifies the power signal and generates a modified power signal capable of dimming LED light sources (and other light sources) that are generally considered to be non-dimmable with conventional dimmers. The dimming signal can be a wireless signal. Exemplary embodiments include a computer application executing on a computer or handheld computer that can be used to remotely dim, via the dimming module, one or more LED light sources (and other light sources) that are generally considered to be non-dimmable with conventional dimmers.
US10257888B2
An electric heating pad for a water tank includes a substrate, a heating layer paved on the substrate, a leading wire that is electrically connected to the heating layer, and a fastener that fixes the leading wire. The substrate is configured with a first through hole that latching to the leading wire. The fastener includes a first fixed part and a second fixed part that are arranged on two faces of the substrate. The second fixed part is configured with a clamp part, and a second through hole matching to the leading wire is arranged at the clamp part. The fastener further includes a connecting rod that connects the first fixed part to the second fixed part, the substrate is configured with a third through hole, and the connecting rod passes through the third through hole to make the substrate be clamped between the first fixed part and the second fixed part.
US10257881B2
Embodiments of the present invention relate to a radio resource control RRC message processing method, apparatus, and system. The method includes: setting up, by a first serving node, a connection to a first anchor node, and setting up, by the first anchor node, a connection to a mobility management entity MME; receiving, by the first serving node, a radio resource control RRC message sent by first user equipment UE, where the RRC message includes an RRC message carried by a signaling radio bearer SRB1 or an RRC message carried by an SRB2; and sending, by the first serving node, the RRC message to the first anchor node.
US10257879B2
A method for establishing at least one control rule for a communication session between a packet communication network and a mobile terminal linked to a mobile network, referred to as a user session, which is carried by a connection between the mobile terminal and a gateway of the mobile network. The gateway is connected to the packet communication network, and a control session is carried by a connection between the gateway and a control entity of the mobile network. The method is implemented by the control entity.
US10257867B2
Systems and methods for allocating a physical cell identifier (PCI) to a cell are described. In one implementation, the method comprises identifying allocated physical cell identifiers based on PCI data and generating a near PCI list and a far PCI list based on the allocated PCIs and a RSRP threshold value. Further, the method comprises determining cell group IDs and a cell IDs from the near PCI list and the far PCI list. Further, the method comprises assigning the cell group IDs to a first bin and the cell IDs to a second bin. Further, the method comprises prioritizing the cell group IDs in the first bin based on effective distance and the cell IDs in the second bin based on an effective RSRP value. Further, the method comprises allocating the PCI, to the cell, determined based on the prioritized cell group IDs and the cell IDs.
US10257866B2
Disclosed is a method and terminal for wireless network access point connection. The method for wireless network access point connection includes: establishing at least one wireless network access point group in a terminal, and setting a common password of the wireless network access point group; and detecting whether a password of each wireless network access point in the wireless network access point group is the common password, and connecting to one wireless network access point with a password which is the common password in the wireless network access point group according to the common password.
US10257861B2
A method of communicating in a wireless network comprises controlling a bandwidth or a transmission mask of a PPDU transmitted by a transmitting STA to a receiving STA within a TXOP based on bandwidth information in at least one preceding frame within the TXOP. The method and associated devices allow a control of TXOP bandwidth or transmission mask where devices capable of both dynamic and static bandwidth operation may be present within the network. The preceding frame may include a non-HT frame of a non-HT duplicate frame exchange, such as a non-HT duplicate RTS/CTS exchange or a BAR/BA exchange, where the bandwidth or the transmission mask would be controlled by being limited to be less than or equal to a bandwidth of the non-HT frame. The preceding frame may include a preceding PPDU, where the bandwidth or the transmission mask would be limited to be less than or equal to a bandwidth of the preceding PPDU.
US10257857B2
A method is implemented by a station (STA) in a Wireless Local Area Network (WLAN) to update a Network Allocation Vector (NAV) maintained by the STA. The method includes receiving a first Physical Layer Protocol Data Unit (PPDU), determining whether a duration indicated in a control field of a preamble portion of the first PPDU is greater than a current NAV value, determining whether the first PPDU is received as an immediate response to a second PPDU previously transmitted by the STA, and updating the NAV maintained by the STA using the duration in response to a determination that the duration is greater than the current NAV value and the first PPDU is not received as an immediate response to the second PPDU previously transmitted by the STA.
US10257856B2
Disclosed is a 5G or pre-5G communication system for supporting a data transmission rate higher than that of a 4G communication system such as LTE. Disclosed are: a method for transmitting a signal in an unlicensed band channel on the basis of a counter reduction in the unlicensed band channel of a mobile communication system and a clear channel assessment (CCA) of the channel; and a mobile communication system, and according to an embodiment of the present disclosure, the method for transmitting a signal in an unlicensed band channel on the basis of a counter reduction in the unlicensed band channel of a mobile communication system and a clear channel assessment (CCA) of the channel comprises the steps of: reducing the counter and performing a CCA for the channel, during a first period of transmitting a discovery signal and data; storing the reduced counter when a second period of transmitting only the discovery signal without the data is started; reducing the counter by using the stored counter and performing the CCA for the channel when a third period of transmitting the discovery signal and the data is started; and transmitting the discovery signal or the data on the channel on the basis of the counter value.
US10257848B2
Methods, systems, and devices for wireless communication are described. A base station may communicate with multiple user equipments (UEs) in a wireless system supporting directional transmission in shared spectrum (e.g., in millimeter wave (mmW) spectrum). The base station may contend for the channel (e.g., using a listen-before-talk (LBT) procedure) and, upon success, transmit a directional channel reservation (CR) signal to each of the multiple UEs. The CR signal may reserve the channel for a specific time period and indicate a start time, an end time, or both. The UE may respond with another CR transmission. In some examples, the base station may transmit CR signals to each of the UEs in a single burst transmission. In other examples, the base station may transmit CR signals to the UEs sequentially, so that if a UE does not respond, the reserved time may be allotted to another UE.
US10257843B2
A digital media device is provided. The digital media device includes a processor, a transceiver configured to be operationally connected with the processor, and a sensor configured to be operationally connected with the processor. The processor may be configured to receive identification information of an object when an event occurs, obtain state information of a user within a specific distance from the object, and create reaction information with respect to the object based on the state information.
US10257842B2
A method and an apparatus for providing zone based prediction. The method includes determining, by a base station, a plurality of zones by dividing a coverage area of a cell, receiving, by the base station, channel state information (CSI) from a user equipment (UE), identifying, by the base station, a first zone from the plurality of zones where the UE encounters an obstructed area based on the CSI at a time domain, and allocating, by the base station, at least one resource to the UE to compensate for signal losses if the UE enters the obstructed area.
US10257836B1
The described technology is generally directed towards a joint procedure in wireless communications for reporting a partial beam failure or performing beam management when no beams have failed. The joint procedure reports the beam management reference signal received power and control beam recovery on a common feedback channel, which avoids the need for a reserved, dedicated feedback channel resource for beam recovery. Also described is configuring a possibly different failure threshold for each selected beam, whereby the network can configure different beams to have different reliability/quality-of-service levels for example.
US10257835B2
Enhanced beam management for a wireless communication system is provided. In one example, a method comprises: determining, by a device comprising a processor, first beam information for a selected first beam of beams associated with a base station device, wherein the selected first beam is for downlink transmission; determining, by the device, second beam information for a selected second beam of the beams associated with the base station device, wherein the selected second beam is an alternative to the selected first beam for transmission of downlink data to the device, and the determining the second beam information is performed during a random access channel procedure; and transmitting, by the device, to a network device, the first beam information and the second beam information.
US10257824B2
The present disclosure generally relates to the field of resource allocation. More specifically, the present disclosure relates to a technique of allocating communication resources in a wireless communication network. The wireless communication network comprises a plurality of access nodes, each of the plurality of access nodes being connected to one or more of the plurality of access nodes via one or more links to provide a plurality of routes for routing data through the wireless communication network. A method embodiment comprises the step of receiving, for one or more links (180, 182) of at least one access node (100) of the plurality of access nodes, allocation information. The allocation information indicates how available communication resources are to be allocated. The method comprises allocating, for the one or more links (180, 182) of the at least one access node (100), the available communication resources based on the received allocation information and a status of one or more data buffers of the at least one access node (100) for buffering data related to one or more of the plurality of routes.
US10257822B2
In a terminal, a control unit transmits a bundle response signal using a resource in a basic region of an uplink control channel in an uplink unit band of a unit band group when no error is detected in each of a plurality of pieces of downlink data of the unit band group, the uplink control channel in the uplink unit band being associated with a downlink control channel in a basic unit band that is a downlink unit band in which a broadcast channel signal including information relating to the uplink unit band is transmitted, and the control unit transmits the bundle response signal using a resource in an additional region of the uplink control channel when an error is detected in each of the plurality of pieces of downlink data.
US10257820B2
The present disclosure relates to the field of mobile communications technology. A Method and a device for transmitting data in an unauthorized frequency band are provided. The method includes: determining a starting position of to-be-transmitted data in a radio frame in the unauthorized frequency band; determining position indication information based on the starting position; and transmitting the position indication information, to enable a terminal to obtain the starting position of the to-be-transmitted data in the radio frame in the unauthorized frequency band based on the position indication information.
US10257817B2
One embodiment of the present invention is a method for a device-to-device (D2D) terminal to transmit and receive a signal in a wireless communication system, the method comprising: receiving downlink control information (DCI) comprising resource allocation information; checking the cyclic redundancy check (CRC) of the DCI by using a D2D radio network temporary identifier (RNTI); and, if there is no error in the result of the CRC check, performing D2D communication on resources denoted in the resource allocation information, wherein if the TPC field of the DCI is a pre-set value, a downlink signal is received from a base station on resources denoted in the resource allocation information.
US10257813B2
Various aspects of the present disclosure enable a plurality of mobile devices (UEs) within a cell to spread out in time their respective transmissions of signaling messages, such as cell update messages, when the network enables or disables enhanced uplink (EUL, sometimes referred to as high-speed uplink packet access or HSUPA) while the UE is in the CELL_FACH state, by changing SIB5 or SIB5bis. In this way, the network load may be reduced, and a network blockage that otherwise might result from large numbers of UEs simultaneously transmitting the cell update message can be avoided. According to one example, a network node may be configured to distribute CELL_UPDATE messages or procedures to UEs when the network node enables or disables EUL in CELL_FACH by changing SIB5 or SIB5bis over time to reduce the network load. According to another example, a UE may be configured for utilizing a random timer or back-off timer to defer cell updates.
US10257806B2
A first communication device allocates respective sub-channels of an orthogonal frequency division multiplexing (OFDM) channel to two or more second communication devices for uplink orthogonal frequency division multiple access (OFDMA) transmission from the two or more second communication devices. A first sub-channel is allocated to a first one of the second communication devices and a second sub-channel is allocated to a second one of the second communication devices. The first communication device provides, to the second communication devices, indications of the respective sub-channels allocated to the second communication devices. The first communication device receives an uplink OFDMA data unit that includes a first OFDM data unit transmitted from the first one of the second communication devices via the first sub-channel, and a second OFDM data unit transmitted from the second one of the second communication devices via the second sub-channel.
US10257805B2
Driving condition data is determined. The driving condition data identifies one or more driving actions that require more driver attention and one or more driving actions that require less driver attention. An indication is received that a user has a mobile device and is driving a vehicle. The surrounding environment of the vehicle is monitored. An incoming notification on the mobile device is received. A distraction value is determined. The distraction value is based on the one or more driving actions and the surrounding environment. The incoming notification is modified based on the distraction value.
US10257799B2
A transport network (20) is connected to a first wireless base station (3, 4) and to a second wireless base station (6). The first wireless base station comprises a remote radio unit (3) and a baseband processing unit (4) which are connected by the transport network (20). A node (16) of the transport network (20) receives a synchronous time division multiplexed communication signal which carries at least a first communication signal between the baseband processing unit (4) and the remote radio unit (3). The node (16) determines a frequency synchronisation signal from the synchronous time division multiplexed communication signal. The node (16) transmits the synchronous time division multiplexed communication signal to the remote radio unit (3) of the first wireless base station. The node (16) transmits the frequency synchronisation signal to the second wireless base station (6). The node (16) also assists with providing phase/time synchronisation to the second wireless base station (6).
US10257798B1
Disclosed are methods, devices and systems for generating accurate timestamps for wireless communications signals that can be used to correct the clocks of base stations for wireless communications systems. A radio signal timestamping unit (RSTU) receives a wireless signal including timing information broadcast by a base station. The RSTU includes a local clock that is in communication with a high-precision time source and provides high-accuracy timing information to one or more base stations to maintain accurate clock synchronization among the plurality of base stations. The timing synchronization information can be determined at least in part based on the propagation delay of the wireless signals received at the RSTU.
US10257793B2
A method for use in a user terminal in a cellular communications system. According to the method, the user terminal applies a first timing advance value to its transmissions to a controlling node, and the user terminal requests communication with the controlling node in a contention based procedure by transmitting an access request (MSG 1), in response to which the controlling node transmits an initiation message (MSG 2) along with a second timing advance value. According to the method, the user terminal uses the first timing advance value if the user terminal loses the contention based procedure, i.e. if the controlling node subsequently continues the initiated communication with said other user terminal.
US10257790B2
Provided is a terminal with which it is possible, in a heterogeneous cell network, to transmit a Periodic-Sounding Reference Signal (P-SRS) at a transmission bandwidth and power density necessary for carrying out both a process of selection of a transceiving participating base station and a process of frequency scheduling of a Physical Uplink Shared Channel (PUSCH). A terminal (300) comprises a receiving unit (301) which receives control information which includes information which denotes a P-SRS transmission parameter, and a transmission unit (303) which, using a transmission parameter which is included in the received control information, transmits a first P-SRS provided with a first bandwidth and a first power density at a first period, and transmits a second P-SRS provided with a second bandwidth which is narrower than the first bandwidth and second power density which is higher than the first power density at a second period.
US10257784B2
Disclosed are a method and an apparatus for generating an STF signal usable in a wireless LAN system. The STF signal is included in a field used to improve AGC estimation of a MIMO transmission. A portion of the STF signal is used to transmit an uplink, and can be used for uplink MU PPDUs transmitted from a plurality of STAs. The STF signal that is disclosed, for example, is used for a 40 MHz band or an 80 MHz band, is desirably usable for the 40 MHz band, and can be generated based on a sequence in which a predetermined M sequence is repeated. The predetermined M sequence can be a binary sequence of which the length is 15 bits.
US10257779B2
The present invention relates to a method and an apparatus for searching for an access point of a terminal in a wireless communication system, and the method for searching for an access point of a terminal in a wireless communication system according to the present invention comprises the steps of: transmitting a probe request frame including an identifier for searching for a specific access point; receiving a probe response frame transmitted from the access point related to the identifier; and connecting to the access point having transmitted the probe response frame.
US10257778B2
A wireless communication system includes a terminal configured to perform wireless communication concurrently using a cell of a first type enabling connection without association with another cell and a cell of a second type enabling connection by being associated with the cell of the first type; and a base station configured to form a first cell of the second type and when detecting that the terminal selects the first cell for the cell of the first type, the base station notifies the terminal of a second cell of the first type different from the first cell so as to allow the terminal to change connection to the second cell.
US10257777B2
A method embodiment includes receiving, by a virtual user-specific service gateway (v-u-SGW) on a processor, a packet, processing the packet, and forwarding the packet to a user equipment (UE). The v-u-SGW is created in accordance with registration of the UE in a network. The method further includes processing the packet in accordance with a configuration of the UE and/or a configuration of the network.
US10257776B2
Embodiments herein provide a method of performing a cell search by user equipment (UE). The method includes receiving a signal from the base station. The method includes estimating a fractional frequency offset (FFO) along with a coarse timing using a cyclic prefix (CP) in the received signal. The method includes compensating the received signal with the estimated FFO. Further, the method includes applying a correlation on the compensated received signal with each of a plurality of primary synchronization signals (PSSs) generated by the UE. Furthermore, the method includes determining a plurality of cell search parameters based on the applied correlation.
US10257772B2
A method of system information (SI) acquisition with reduced signaling overhead is proposed. To reduce SI broadcast overhead, the quantity of periodic SI broadcast and the frequency of on-demand SI acquisition need to be reduced. In order to reduce the quantity of periodic SI broadcasting, on-demand SI delivery is enabled. With on-demand SI delivery, signaling overhead is proportional to the frequency of SI acquisition. From the network side, the base stations proactively provide SI delivery options and delivers SI over unicast or scheduled broadcast. From the UE side, UE determines how to acquire SI, i.e., by listening to broadcast or by sending an on-demand request via existing procedures such as a random-access procedure over a random-access channel (RACH).
US10257761B2
Embodiments relate to systems, methods, and computer readable media to enable a millimeter wave capable small cell (MCSC) devices to receive a handover of a user equipment from a universal mobile telecommunications system terrestrial radio access node B (eNB.) In particular, systems and methods are described for user equipment (UE) association with a MCSC operating as a booster for an eNB, including identification of and communication on preferred cell sector between the UE and the MCSC.
US10257758B2
The claimed subject matter includes techniques for migrating wireless channels. An example method includes initiating, via a first media access controller on an integrated circuit chip, a first connection on a first wireless channel. The example method also includes performing, via a second media access controller on the integrated circuit chip, a scan on additional wireless channels using a second media access controller. The example method also includes detecting, via the second media access controller, an available wireless channel from the additional wireless channels. The method further includes migrating, via the first media access controller, the first connection from the first wireless channel to the available wireless channel. The method further includes combining the second access media controller with the first media access controller to provide increased throughput or signal quality on the available wireless channel.
US10257746B2
Methods and apparatus for reducing and/or canceling signal interference between receiver and transmitter components of a wireless communications device are described. The methods and apparatus are well suited for use in a wide range of devices including user equipment devices such as cell phones as well as in network equipment such a base stations. Opto-mechanical devices are used in some embodiments as part of an apparatus which performs interference cancelation on RF (Radio Frequency) signals.
US10257744B2
According to an embodiment of the present invention, disclosed is a method for supporting, by a serving base station, cancellation of interference signals from signals received at a target terminal in a wireless communication system. The method comprises the steps of: receiving scheduling information of at least one neighboring base station from the at least one neighboring base station; configuring a set of auxiliary information for canceling the interference signals of a target terminal on the basis of the scheduling information of the at least one neighboring base station; and transmitting the set of auxiliary information for canceling the interference signals of the target terminal to the target terminal, wherein the auxiliary information comprises at least one of demodulation reference signal (DM-RS) related information and cell-specific reference signal (CRS) related information in association with interference signals from respective neighboring base stations.
US10257741B2
A base station transmits configuration parameters of a plurality of cells to a wireless device. The plurality of cells comprise: a primary cell with a primary physical uplink control channel (PUCCH); and a PUCCH secondary cell with a secondary PUCCH; a transmit power control (TPC) radio network temporary identifier (RNTI); a primary TPC index for the primary PUCCH; and a secondary TPC index for the secondary PUCCH. An activation control element indicating activation of the PUCCH secondary cell is transmitted. A downlink control information (DCI) associated with the TPC RNTI is transmitted via a common search space of the primary cell. The DCI comprises an array of TPC commands. The secondary TPC index determines a TPC command in the array. An uplink signal with an uplink signal transmission power determined based on the TPC command is received from the wireless device and via the secondary PUCCH.
US10257734B2
A method and apparatus for indicating a logged multimedia broadcast multicast service (MBMS) measurement availability in a wireless communication system is provided. A user equipment (UE) determines whether to inform a serving cell that the UE has logged MBMS measurement results to be reported based on a first condition and a second condition, and when both the first condition and the second condition are met, the UE informs the serving cell that the UE has the logged MBMS measurement results. The first condition corresponds to that the UE 0has the logged MBMS measurement results to be reported. The second condition includes at least one MBMS minimization of drive tests (MDT) related condition.
US10257731B2
For determining operational status of components of a wireless signal transmission environment, a signal is received from a client power receiver (CPR), and at least one waveform characteristic value of the signal is calculated. Based on the determined waveform characteristic value(s), a current transceiver system operational status is computed for the CPR at a current location. The determined current transceiver system operational status is compared with a prior-stored last known good transceiver system operational status for the CPR at the current location, and it is determined if, as a result of the comparing, the current transceiver system operational status matches the prior-stored last known good transceiver system operational status for the CPR at the current location. Determining a presence or an absence of the match facilitates identifying one of a presence and an absence of: functional problem(s) in: at least one of the transceiver system and the CPR.
US10257727B2
Systems and methods are disclosed for providing at least one report relating to a wireless communications spectrum. At least one device is operable for wideband scan; to detect and measure at least one signal transmitted from at least one signal emitting device autonomously, thereby creating signal data; to analyze the signal data in near real-time, thereby creating analyzed data; generate the at least one report in near real-time; and to communicate at least a portion of the at least one report over a network to at least one remote device.
US10257722B2
A method and system are provided. The system includes a communication system including a first transmitter/receiver operating on a first frequency and a second transmitter/receiver operating on a second frequency. The system also includes a controller monitoring at least one of interference and throughput on the first and second transmitter/receiver and shifting demand based on the monitoring.
US10257713B2
Improved systems and techniques for communication in an environment in which muting of resources is used to avoid interference between cells. If a cell, represented by a macro eNB for example, is muting resources, those resources can be made available, under appropriate conditions, to user devices, such as UEs, engaging in device to device communication. Allocation of muted resources to D2D UEs can be based on meeting of conditions, such as that the D2D UEs be outside of a specified proximity to a cell, such as a small cell, using the resources, or that the D2D UEs transmit at less than a specified power. The UEs may take measurements to determine if the conditions are met and report the measurements to their base stations, which then determine whether to allocate the muted resources and configure the UEs with resource allocation information.
US10257712B2
According to one embodiment of the invention, a non-transitory computer readable medium comprising instructions which, when executed by one or more hardware processors, cause performance of operations comprising entering, by a first access point associated with a wireless network, a first mode for collecting network data from one or more access points associated with the wireless network, entering, by the first access point, a second mode for transmitting data to and from one or more client devices associated with the wireless network, and when a number of access points associated with the wireless network is greater than or equal to a number of channels of the wireless network, (i) collecting, by the first access point, network data of a first channel of the wireless network and (ii) receiving, by the first access point, network data of a second channel of the wireless network from a network coordination device is shown.
US10257711B2
In order for making MTC more efficient and/or secure, a base station forming a communication system connects a UE to a core network. A node serves as an entering point to the core network for a service provider, and transmits traffic between the service provider and the UE. The node establishes, as a connection to the base station, a first connection for directly transceiving messages between the node and the base station. Alternatively, the node establishes a second connection for transparently transceiving the messages through a different node that is placed within the core network and has established a different secure connection to the base station.
US10257709B2
Some embodiments provide a method for bypassing device security protections to communicate with a contact of a secure device. The method displays a selectable user interface object on the device enabling a user to bypass the security protections of the device. Upon receiving a selection of the user interface object, the method initiates a communication to a contact that is preselected from a list of contacts.
US10257701B2
Mechanisms for authenticating a connection between a user device and a streaming media content device comprising: identifying a collection of candidate streaming media content devices based on beacon(s) detected by a user device; receiving an indication that one of the content devices is to be selected for connection to the user device; transmitting instructions to the content devices to broadcast a signal, wherein the signal broadcast by each of the content devices contains a value that indicates an identity of the content device; receiving, from the user device, an audio signal that includes a detected signal; processing the audio signal to extract the value indicating the identity of a particular content device associated with the detected signal contained in the received audio signal; identifying the particular content device based on the determined value; and transmitting an indication that the user device and the particular content device are authenticated to communicate.
US10257696B2
Methods and apparatus are provided for sharing device capabilities of Universal Plug and Play (UPnP) devices with a service provider entity. Device capabilities of one or more UPnP devices in a UPnP home network environment are obtained. The device capabilities are aggregated. The aggregated device capabilities are mapped in a user agent profile. The user agent profile including the device capabilities is communicated to the service provider entity so that the service provider entity delivers telephony services to the one or more UPnP devices according to respective device capabilities.
US10257682B2
A method at a computing device for dedicated short range communication with traffic offload, the method including utilizing a radio in a communications subsystem on the computing device for a first category of communications; determining, at the computing device, that a trigger condition has been met; and splitting operation of the radio in the communications subsystem of the computing device, the splitting comprising utilizing a first portion of the radio for the first category of communications and a second portion of the radio for a second category of communications.
US10257678B2
Data discovery for sensor data in an M2M network uses probabilistic models, such as Gaussian Mixing Models (GMMs) to represent attributes of the sensor data. The parameters of the probabilistic models can be provided to a discovery server (DS) that respond to queries concerning the sensor data. Since the parameters are compressed compared to the attributes of the sensor data itself, this can simplify the distribution of discovery data. A hierarchical arrangement of discovery servers can also be used with multiple levels of discovery servers where higher level discovery servers using more generic probabilistic models.
US10257672B2
In one example, a method includes receiving, from a client application executing on a client device, a message transmission request including a number assigned to a recipient device. The message transmission request is added to an outbound queue based on determining the message transmission request is valid. The message request is caused to be transmitted to the recipient device based on the message transmission request being included in the outbound queue. Status information is obtained specifying a status of transmission of the message, the status information including an indication of successful transmission of the message. A record of the message transmission request responsive to the causing the transmission of the message is stored, the storing including storing the message and the indication of successful transmission of the message.
US10257671B2
A system and method for sending text messages and, more particularly, a system and method for forcing SMS capable devices to communicate via SMS using, for example, SS7 protocol. A method includes providing a tag forcing a return text message to be sent via SS7 protocol. In use, the system and method is configured to force the use of SMS messages via the SS7 protocol. The system and method can be implemented over any network, for example, and any existing mobile device and related infrastructure can be modified to take advantage of the benefits and functionality of the system and method of the invention.
US10257667B2
A data transmission method and device, where the method includes determining, by a first station device, that a second station device supports a first service, receiving a device group join request message that is sent by the second station device according to a media access control (MAC) address of a first device group, where the first device group is a device group of the first service and is a device group to which the first station device belongs, sending a device group join response message to another station device in the first device group and the second station device according to the multicast MAC address of the first device group in a contention transmission manner, and performing data transmission of the first service with the second station device in a service window of the first service, where the service window includes a time and/or a channel of service transmission.
US10257650B2
The disclosure relates to a method, performed by at least one apparatus. The method may include obtaining new opportunity signal data pertaining to an opportunity signal source and indicating opportunity signal values for particular locations at a site; obtaining previous opportunity signal data pertaining to said opportunity signal source and indicating opportunity signal values for particular locations at said site; comparing at least a part of said opportunity signal values of said new opportunity signal data pertaining to said opportunity signal source of said site and said opportunity signal values of said previous opportunity signal data pertaining to said opportunity signal source of said site for corresponding locations at said site; and classifying said opportunity signal source based at least in part on said comparing.
US10257647B2
This specification describes a method comprising detecting presence of a portable device in a vicinity of a first vehicle based on an identifier of the portable device which is detected at first user equipment, UE, located at the first vehicle, and further comprising causing transmission, from the first UE to a second UE located at a second vehicle in the vicinity of the first vehicle, of the identifier of the portable device and measurement data relating to the portable device and collected at the first vehicle, the measurement data being for use at the second vehicle to determine the location of the portable device relative to the second vehicle.
US10257645B2
Some demonstrative embodiments include apparatuses, systems and/or methods of Neighbor Awareness Networking (NAN) Geo-Fencing. For example, an apparatus may include circuitry configured to cause a Neighbor Awareness Networking (NAN) device to process a plurality of geo-fencing parameters of a geofence from an application on the NAN device; and perform geo-fencing with another NAN device based on the geo-fencing parameters.
US10257641B2
The present application relates to a method whereby the communication traffic between a wireless communication apparatus such as a smartphone and another device such as a map information providing server and/or server managed by mobile virtual network operator MVNO. According to a first aspect, the communication traffic can be reduced by dividing items of geographical information that are sent to the smartphone are divided into static information and dynamic information and the two types of information are separately processed in that the map data is updated less often than information such as traffic congestion, weather information or the congestion level of a base station. According to a second aspect, congestion information is derived by averaging over time the number of vehicles which pass through a certain point. According to a third aspect, the updating interval, i.e. the frequency by which new information will be downloaded from the server, is adapted to degree of change of the dynamic information over time. According to a fourth aspect, the updating interval is adapted to the movement speed of the smartphone. According to a fifth aspect, download rates of a communication carrier are displayed on top of a map, thereby providing some sort of geobrowsing. According to a sixth aspect, an MVNO informs its subscribers about base station related information, such as signal intensity and the base station's congestion level. According to a seventh aspect, the smartphone selects, on the basis of the various items of information received, another network, either manually or automatically.
US10257636B2
Described herein is a method (30) of rendering an audio signal (17) for playback in an audio environment (27) defined by a target loudspeaker system (23), the audio signal (17) including audio data relating to an audio object and associated position data indicative of an object position. Method (30) includes the initial step (31) of receiving the audio signal (17). At step (32) loudspeaker layout data for the target loudspeaker system (23) is received. At step (33) control data is received that is indicative of a position modification to be applied to the audio object in the audio environment (27). At step (38) in response to the position data, loudspeaker layout data and control data, rendering modification data is generated. Finally, at step (39) the audio signal (17) is rendered with the rendering modification data to output the audio signal (17) with the audio object at a modified object position that is between loudspeakers within the audio environment (27).
US10257635B2
The invention improves HOA sound field representation compression. The HOA representation is analysed for the presence of dominant sound sources and their directions are estimated. Then the HOA representation is decomposed into a number of dominant directional signals and a residual component. This residual component is transformed into the discrete spatial domain in order to obtain general plane wave functions at uniform sampling directions, which are predicted from the dominant directional signals. Finally, the prediction error is transformed back to the HOA domain and represents the residual ambient HOA component for which an order reduction is performed, followed by perceptual encoding of the dominant directional signals and the residual component.
US10257632B2
Higher Order Ambisonics (HOA) signals can be compressed by decomposition into a predominant sound component and a residual ambient component. The compressed representation comprises pre-dominant sound signals, coefficient sequences of the ambient component and side information. For efficiently combining HOA decompression and HOA rendering to obtain loudspeaker signals, combined rendering and decoding of the compressed HOA signal comprises perceptually decoding the perceptually coded portion and decoding the side information, without reconstructing HOA coefficient sequences. For reconstructing components of a first type, fading of coefficient sequences is not required, while for components of a second type fading is required. For each second type component, different linear operations are determined: one for coefficient sequences that in a current frame require no fading, one for those that require fading-in, and one for those that require fading-out. From the perceptually decoded signals of each second type component, faded-in and faded-out versions are generated, to which the respective linear operations are applied.
US10257626B2
Disclosed herein, among other things, are systems and methods for fitting hearing assistance devices. One aspect of the present subject matter includes a method for assisting wearers in adjusting settings of hearing assistance devices using a mobile adaptation tool. The method includes providing a mobile adaptation tool for a wearer of a hearing assistance device. The wearer is guided using gamification to adjust settings of the hearing assistance device using the mobile adaptation tool, including providing an update to the wearer via the adaptation tool with an indication of a level of matching between current settings and target settings, according to various embodiments.
