US10227687B2
A hard lubrication film, with which a surface of a base material is coated, has two or more alternately laminated layers that are one or more A-layers made of (CraMobWcVdBe)1−x−yCxNy and one or more B-layers made of (CraMobWcVdBe)1−x−y−zCxNyOz. Atom ratios a, b, c, d, e=1−a−b−c−d, x+y, and y related to A-layers satisfy 0.2≤a≤0.7, 0.05≤b≤0.6, 0≤c≤0.3, 0≤d≤0.05, 0≤e≤0.05, 0.3≤x+y≤0.6, and 0≤y≤0.6, respectively. Atom ratios a, b, c, d, e=1−a−b−c−d, x, y, z, and x+y+z related to B-layers satisfy 0.2≤a≤0.7, 0.05≤b≤0.6, 0≤c≤0.3, 0≤d≤0.05, 0≤e≤0.05, 0≤x≤0.6, 0≤y≤0.6, 0
US10227685B2
A method for forming an iron sprayed coating on a substrate with droplets of a wire molten by an electric arc includes: a step of forming a first iron sprayed coating on the substrate, the wire for arc spraying being a first wire containing iron and 0.03 to 0.10% by mass of carbon and the compressed gas being inert gas; and a step of forming a second iron sprayed coating on the first iron sprayed coating, the wire for arc spraying being a second wire containing iron and 0.03 to 0.10% by mass of carbon and the compressed gas containing 10 to 21% by volume of oxygen gas.
US10227678B2
A high-temperature, high-strength, oxidation-resistant cobalt-nickel base alloy is disclosed. The alloy includes, in weight percent: about 3.5 to about 4.9% of Al, about 12.2 to about 16.0% of W, about 24.5 to about 32.0% Ni, about 6.5% to about 10.0% Cr, about 5.9% to about 11.0% Ta, and the balance Co and incidental impurities. A method of making an article having high-temperature strength, cyclic oxidation resistance and corrosion resistance is disclosed. The method includes forming a high-temperature, high-strength, oxidation-resistant cobalt-nickel base alloy as described herein; forming an article from the alloy; solution-treating the alloy by a solution heat treatment; and aging the alloy by providing at least one aging heat treatment at an aging temperature that is less than the gamma-prime solvus temperature, wherein the alloy is configured to form a continuous, protective, adherent oxide layer on an alloy surface upon exposure to a high-temperature oxidizing environment.
US10227675B2
A wet smelting method for nickel oxide ores from which nickel, cobalt, etc. are recovered is provided with which it is possible to reduce the consumption of an acid in leaching, such as sulfuric acid, and to recover valuable metals. The method comprises: step (A) in which nickel oxide ores as a raw material are separated into a limonite-type ore having a low magnesium content and a saprolite-type ore having a high magnesium content; step (B) in which the saprolite-type ore is subjected to normal-pressure leaching under given standardized leaching conditions using the pressure leachate obtained by pressure leaching in step (C); and step (C) in which the limonite-type ore obtained in step (A) is mixed with the normal-pressure leaching residue obtained in step (B) and the mixture is reacted with sulfuric acid in an acidic atmosphere having a high temperature and a high pressure, thereby conducting pressure leaching.
US10227672B2
A high-strength hot-dip galvanized steel sheet having a surface coated with a hot-dip galvanized coating, the steel sheet having a chemical composition comprising C: more than 0.10% and less than 0.18%, Si: 0.01 to 1.00%, Mn: 1.5 to 4.0%, P: 0.100% or less, S: 0.020% or less, Al: 0.010 to 0.500%, Cr: 0.010 to 2.000%, Nb: 0.005 to 0.100%, Ti: 0.005 to 0.100%, B: more than 0.0005% and 0.0030% or less, and Fe and incidental impurities, and a method for producing the same. The steel sheet has a microstructure including ferrite having an area fraction in the range of 0 to 10%, martensite having an area fraction in the range of 15 to 60%, tempered martensite having an area fraction in the range of 20 to 50%, and bainitic ferrite having an area fraction in the range of 20 to 50%.
US10227665B2
A method for identifying a risk factor for diseases, disorders or conditions, such as those caused by human immunodeficiency virus, using the polymerase chain reaction and specific primers. Methods for treating patients having these diseases, disorders or conditions by antimicrobial treatment of the risk factor by combined antiviral and antibacterial treatment or by sustaining or stimulating the subject's immune system. Methods for screening biological products including red blood cell preparations. Primers and methods for detecting nucleic acids or microbial agents associated with red blood cells, such as those associated with red blood cells in subjects infected with HIV and undergoing antiretroviral therapy.
US10227663B2
Methods and systems are provided for packaging reporter nucleic acid molecules into non-replicative transduction particles for use as reporter molecules. The non-replicative transduction particles can be constructed from viruses and use viral transduction and replication systems. The reporter nucleic acid molecules include a reporter gene, such as a reporter molecule or selectable marker, for detecting target genes or cells. Methods and systems are provided for detection of cells and target nucleic acid molecules using the non-replicative transduction particles as reporter molecules.
US10227660B2
A method for detecting toxigenic Clostridium difficile (C. difficile) by strand-invasion based DNA amplification is provided, together with oligonucleotides, compositions and kits suitable for use in this method.
US10227659B2
The invention relates to the identification of genetic signatures and expression profiles that are a part of the Base Excision Repair (BER) pathway, a major DNA repair pathway that modifies base lesions. In one embodiment, the present invention provides a method of determining responsiveness of treatment by BER inhibitors for malignant glioma by determining the presence of a low level of expression of Apex 1, a low level of expression of Apex 2, and a high level of expression of MPG.
US10227657B2
A method for increasing sensitivity for detecting minority mutations in MYD88 uses a locked nucleic acid oligo to block amplification of wild-type DNA in DNA isolated from patient FFPE tissue, bone marrow aspirate or peripheral blood samples during PCR while still allowing sequencing and visualization of the PCR product. Further improvement to the sensitivity may be achieved by using a uracil DNA-glycosylase treatment to remove sequence artifacts commonly found in formalin-fixed, paraffin-embedded tissue.
US10227654B2
The present invention provides methods for discovering agents that are effective in reversing epigenetic silencing by inhibiting the interaction of methyl-binding (MBD) proteins with methylated genomic DNA. Also provided are methods for reactivating silenced genes having CpG island hypermethylation along with methods for treatment and prevention of diseases, such as cancer and sickle cell anemia, by administering an agent that modulates methyl-binding domain (MBD) protein-mediated transcriptional repression, thereby increasing gene transcription to prevent or treat disease. Additionally, compounds identified by the present invention useful for treatment and prevention of diseases, such as cancer and sickle cell anemia, are provided.
US10227652B2
A system and method for determining the genetic data for one or a small set of cells, or from fragmentary DNA, where a limited quantity of genetic data is available, are disclosed. Genetic data for the target individual is acquired and amplified using known methods, and poorly measured base pairs, missing alleles and missing regions are reconstructed using expected similarities between the target genome and the genome of genetically related subjects. In accordance with one embodiment of the invention, incomplete genetic data is acquired from embryonic cells, fetal cells, or cell-free fetal DNA isolated from the mother's blood, and the incomplete genetic data is reconstructed using the more complete genetic data from a larger sample diploid cells from one or both parents, with or without genetic data from haploid cells from one or both parents, and/or genetic data taken from other related individuals.
US10227641B2
Methods and compositions are provided for improving specificity during amplification of a target DNA sequence. The methods and compositions rely upon the use of an RNase H enzyme, a polymerase, and RNase H enzyme-sensitive, blocked-cleavable oligonucleotide primers in the amplification reactions, wherein the reaction mixtures include either an optimized final concentration of a divalent metal salt comprising 2.0 mM or less of free Mg++ cation and/or an optimized final concentration of a non-ionic detergent comprising at least about 0.001% polyethylene glycol hexadecyl ether.
US10227635B2
The invention generally relates to methods of performing a capture reaction. In certain embodiments, the method involves obtaining a nucleic acid, fragmenting the nucleic acid, and capturing a target sequence on the nucleic acid fragment using a capture moiety, such as a molecular inversion probe.
US10227633B2
The present disclosure provides a portable device for purifying biological sample. The device comprises a housing and a cartridge holder accommodated in the housing for holding at least one cartridge configured to purify the biological sample. At least one pump is positioned in the housing which is fluidly connectable to the cartridge to circulate the sample and one or more fluids through the cartridge. Further, at least one heating element is configured to heat a matrix chamber in the cartridge. At least one actuator is disposed in the housing to actuate one or more valves to selectively route the biological sample and the one or more fluids in the cartridge. A control unit is interfaced with the actuator, the heating element and the pump and is configured to regulate operation of the actuator, the pump and the heating element during purification of the biological sample.
US10227631B2
The present invention generally relates to air sampling of biological compounds. Specifically, the present invention relates to a device and method for sampling the ambient air for detecting microbial propagules, microbial propagules being any spore, vegetative cell, or virion of microbiological origin including all bacteria, fungi, viruses, protozoans, molds, slime molds, chlamydospores, hyphae, and cysts.
US10227630B2
We describe a method for mining microbial genomes to discover antimicrobial genes and proteins having broad spectrum of activity. Also described are antimicrobial genes and their expression products from various microbial genomes that were found using this method. The products of such genes can be used as antimicrobial agents or as tools for molecular biology.
US10227629B2
Methods for diagnosing, treating, and monitoring the treatment of invasive aspergillosis (IA) are described. The methods can include detecting the presence of one or more volatile organic compounds (VOCs) in the breath of subjects suspected of having IA.
US10227621B2
The present invention relates to methods for preparing an aqueous acrylamide solution having a low acrylic acid concentration. In addition, the present invention relates to methods for reducing the acrylic acid concentration of an aqueous acrylamide solution. The methods involve a bioconversion of acrylonitrile to acrylamide in the presence of a biocatalyst, wherein during the bioconversion the content of acrylonitrile is maintained at 0.3 w/w % or more referred to the total weight of the composition in the reactor. Also provided is an aqueous acrylamide solution which is obtained by the methods of the present invention. Furthermore, the present invention is related to an acrylamide homopolymer or copolymer obtained by polymerizing the acrylamide of the aqueous solution.
US10227618B2
The present application relates to a microorganism of the genus Saccharomyces producing lactic acid and a method for preparing lactic acid using the same. More specifically, the present application relates to a microorganism of the genus Saccharomyces producing lactic acid, wherein the microorganism is modified to weaken or inactivate the activity of pyruvate decarboxylase (PDC) compared to its endogenous activity, to introduce the activity of ATP-citrate lyase (ACL), and to enhance pyruvate biosynthetic pathway compared to its endogenous biosynthetic pathway, and a method for producing lactic acid using the microorganism.
US10227606B2
The present invention pertains to a method for increasing the photosynthesis and yield/growth of plants, and a transgenic plant which is used in the method.
US10227602B2
A genetically modified fruit-producing plant, said plant having sufficiently reduced total Polyphenol Oxidase (PPO) activity relative to a wild type of said plant to reduce browning in the fruit of said plant relative to said wild type, wherein the reduced total PPO activity results from a reduction in activity of at least two PPO isoenzymes in said plant relative to said wild type, or a cell, seed, seedling, part, tissue, cell, fruit or progeny of said plant.
US10227596B2
A translational control method using an RNA-protein interaction motif is provided. The method comprises a step of introducing an mRNA having: a 5′UTR regulation structure comprising: (1) a cap structure at the 5′ terminus, (2) a spacer positioned on the 3′ side of the cap structure, and (3) one or more RNA motifs positioned on the 3′ side of the spacer, which comprises an RNA-protein interaction motif-derived nucleotide sequence or a variant thereof; and a nucleotide sequence encoding a target protein gene on the 3′ side of the 5′UTR regulation structure, into a cell in the presence of a protein specifically binding to the RNA motifs, wherein a translational level is decreased as the number of bases of the spacer decreases, and the translational level is decreased as the number of the RNA motifs increases.
US10227595B2
Provided is a ramp tag capable of solving instability in translation rate resulting from poor compatibility between codons in a foreign gene and a host when expressing a recombinant protein in E. coli. Unlike the conventional codon optimization or codon deoptimization method for solving the problem of rare codons, the present invention increases an expression efficiency of a target protein by merely having the ramp tag be fused with a target gene or independently expressed, without changing the original codon sequence, thereby allowing tRNA to be reused. Thus, the present invention provides a novel method for increasing recombinant protein expression which is capable of reducing costs and time in comparison to the codon optimization method that artificially synthesizes DNA sequences. Therefore, it is expected that the method of the present invention will be able to be used in production of high value-added pharmaceuticals or industrial enzymes.
US10227593B2
Some embodiments comprise methods, systems, and compositions to produce and/or administer modified exosomes or other vesicles containing one or more selected microRNAs, including but not limited to, miR-146b. Some embodiments also comprise the therapeutic administration and use of such modified exosomes and/or producer cells to treat mammalian brain or neurologic injuries and diseases, including in human beings.
US10227592B2
Provided is an RNA interference-inducing nucleic acid comprising at least one nucleic acid strand, the at least one nucleic acid strand comprising a modification substituted to a spacer, which is unable to form a base pair, in the 5′ end or the 3′ end region. The RNA interference-inducing nucleic acid is a modified form of nucleotide provided to prevent off-target effects, offering a method to selectively repress target gene expression. The RNA interference-inducing nucleic acid provides modified forms with target selectivity and specificity as a method to block the off-target effects while silencing the target gene expression, whereas the usage of conventional RNA interference-inducing nucleic acids cause inaccuracy and adverse effects through off-targets, thereby the RNA interference-inducing nucleic acid was offered to solve the problem, wherein it will be widely used as a method for repressing gene expression in research and for gene therapy without concerning the off-target effects.
US10227591B2
The present invention relates to miR145, miR132, miR212, and the genes or gene products regulated by these miRNAs. miR145 is downregulated in cells infected with HCMV. This downregulation modulates expression of miR145 target genes, including IRS-1. Transfection of cells with a miR145 agent, such as a miR145 mimetic, reduces HCMV replication and protein expression. miR132 and miR212 are upregulated in cells infected with HCMV. This upregulation modulates expression of miR132 and miR212 target genes, including MeCP2 and RICS. Transfection of cells with a miR132 and/or a miR212 antagonist reduces HCMV replication and protein expression. Accordingly, the invention provides methods of attenuating HCMV replication by modulating, for example, miR145, miR132, and/or miR212, and targets thereof. Also provided are methods of detecting an HCMV infection, and compositions and kits useful for attenuating HCMV replication.
US10227590B2
An antisense molecule capable of binding to a selected target site to induce exon skipping in the dystrophin gene, as set forth in SEQ ID NO: 1 to 214.
US10227585B2
The invention provides methods for preparing DNA sequencing libraries by assembling short read sequencing data into longer contiguous sequences for genome assembly, full length cDNA sequencing, metagenomics, and the analysis of repetitive sequences of assembled genomes.
US10227580B2
Methods, devices and kits for the physical separation of plankton into its component parts utilizing phototactic behavior are described. The methods utilize positive phototactic behavior and negative contrast orientation of the zooplankton for maximal in situ separation of phytoplankton and zooplankton for use in further studies and evaluation of separation efficiency. The devices provide effective conditions for use in the separation of plankton into component parts.
US10227579B2
The present invention relates to GH61 polypeptide variants. The present invention also relates to polynucleotides encoding the variants; nucleic acid constructs, vectors, and host cells comprising the polynucleotides; and methods of using the variants.
US10227577B2
Methods for the production, capturing and purification of recombinant human lysosomal proteins are described. Such recombinant human lysosomal proteins can have high content of mannose-6-phosphate residues. Also described are pharmaceutical compositions comprising such recombinant human lysosomal proteins, as well as methods of treatment and uses of such recombinant human lysosomal proteins.
US10227574B2
This disclosure provides various TcBuster transposases and transposons, systems, and methods of use.
US10227571B2
The present invention relates to a Siphoviridae bacteriophage Lac-PLP-1 that is isolated from the nature and can kill Lactobacillus plantarum cells specifically, which has a genome represented by the nucleotide sequence of SEQ. ID. NO: 1 (Accession NO: KCTC 12665BP), and a method for preventing and treating the contaminations of Lactobacillus plantarum by using the composition comprising the bacteriophage as an active ingredient.
US10227559B2
The present invention provides a compounded cell culture medium powder formulation comprising: a basal medium powder and a cell culture media supplement, wherein the cell culture media supplement comprises and one or more salts; one or more growth factors; one or more inorganic ions; an amino acid supplement comprising one or more of asparagine, glutamine, histidine, and serine; one or more buffers; and one or more anti-foaming agents. The invention further provides methods of making a compounded cell culture medium powder formulation methods of making a cell culture medium for growing mammalian cells and methods of producing a protein of interest by culturing cells in the cell culture medium and isolating the protein of interest.
US10227558B2
The invention relates to a zinc-enriched biomass comprising living or subsequently killed micro-organisms, selected from the group consisting of Streptococcus thermophilus and Bifidobacterium animalis subsp. lactis and combinations thereof, a method for the manufacture of said zinc-enriched biomass, as well as food preparations, nutraceutic products, functional foods, cosmetic and cosmeceutic products, and food supplements, comprising the said biomass. Furthermore, new micro-organism strains are described which are able to concentrate zinc within the cell in very high amounts and therefore are particularly suitable for use in the method of the invention.
US10227546B2
Disclosed is a lubricating oil composition comprising the reaction product of a nitrogen containing reactant wherein the nitrogen containing reactant comprises an alkyl di-alkanolamide, an alkyl di-alkanolamine, or mixtures thereof; an acidic molybdenum compound; and a salicylate compound.Also disclosed is a method for operating an internal combustion engine comprising said lubricating composition and a method for preparing a molybdenum containing friction modifier.
US10227545B2
The present invention relates to new ether carboxylic acids as high temperature stable rheology modifier, viscosifier, lubricant or emulsifier additives in oilfield and industrial applications. In particular, the invention relates to an ether carboxylic acid or a derivative thereof obtainable by reacting a branched polyol alkoxylate with a halogen carboxylic acid or a halogen carboxylic acid derivative. Further aspects of the invention relate to a lubricant composition comprising an ether carboxylic acid of the invention and the use of said ether carboxylic acid.
US10227542B2
Disclosed is an oil composition with improved fuel economy and durability. The oil composition may be effective in improving fuel economy by reduction of friction on sliding parts of vehicle engines and in preventing abrasion of the engines by effective dispersion of soot in respective parts of the engines. The oil composition comprises a detergent dispersant, a friction reducer and a viscosity controller, which are suitably optimized at a mix ratio of those components.
US10227533B2
Paraffins and waxes are produced from a gaseous feed stream comprising hydrogen and carbon monoxide in a Fischer-Tropsch reactor using a fixed bed of reduced Fischer-Tropsch catalyst having cobalt as catalytically active metal. A nitrogen-containing compound is added to the gaseous feed stream in a concentration of up to 10 ppmV and the mixture if fed to the reactor to obtain paraffins having from 5 to 300 carbon atoms. The product is subjected to a hydrogenation step, to obtain a hydrogenated fraction comprising 5 to 300 carbon atoms. The hydrogenated product is separated into C5-C9, C10-C17, and C18-300 fractions. The C18-C300 fraction is separated to obtain one or more first light waxes having a congealing point in the range of 30 to 75° C. and a second heavy wax having a congealing point in the range of 75 to 120° C.
US10227528B2
The present invention relates to compounds which are suitable for use in electronic devices, and to electronic devices, in particular organic electroluminescent devices, comprising these compounds.
US10227521B2
Methods for selectively replacing the larger particles screened from a drilling fluid may include: circulating a drilling fluid comprising a base fluid and a plurality of particles through a wellbore penetrating a subterranean formation; passing the drilling fluid over a screen having a mesh size, thereby separating the plurality of particles into screened particles having a diameter greater than or equal to the mesh size and retained particles having a diameter smaller than the mesh size; adding a concentration of replenishment particles to the drilling fluid that comprises the base fluid and the retained particles, wherein a PSD of the replenishment particles has a d25REP greater than or equal to the mesh size; and re-circulating the drilling fluid including the replenishment particles back into the wellbore.
US10227510B2
The present invention relates to an optical adhesive film including plate-type inorganic nanoparticles and a curable resin. The optical adhesive film has improved barrier characteristics to moisture and gas, improved light-transmittance, and excellent durability and peel characteristics.
US10227504B2
The present invention describes new crosslinkers for coating compositions, their preparation, and their use.
US10227503B2
A cationic-stabilized dispersion for use in fabricating an in-mold coated article including at least one of a cationic-stabilized polyurethane dispersion, a cationic-stabilized acrylic dispersion, a cationic-stabilized polyacrylamide dispersion, a cationic-stabilized polyallylamine dispersion, a cationic-stabilized polyetheramine dispersion, and a cationic-stabilized chitosan dispersion.
US10227501B2
A UV-curable hard coating composition and a coated article coated with the coating composition are provided herein. The UV-curable hard coating composition can be coated on a plastic material such as polycarbonate to form a coated film having excellent material adhesion, abrasion resistance, and weather resistance. The coating composition may be coated by a general coating method. In some instances, inorganic particles as a coating component are not included in the coating composition. Few foreign substances are generated during spray-coating using the composition. The coating composition can be easily stored. Also, the coated article can be polished or recoated with the UV-curable hard coating composition if needed.
US10227500B2
A latex polymer of multi-stage polymerization comprising a first stage polymer and a second stage polymer wherein the first stage polymer comprises a first portion of an acrylic monomer and a first portion of a phosphorus acid monomer, and the second stage polymer comprises a second portion of an acrylic monomer and a second portion of a phosphorus acid monomer. A process of making such latex polymer.
US10227497B2
An active energy ray curable composition is provided. The active energy ray curable composition includes a polymerizable monomer, a polymer component, a polymeric dispersant, and a pigment. The active energy ray curable composition is non-aqueous. The active energy ray curable composition has a yield value of 0.1 Pa or less either when having an initial weight or when being dried to have a weight 70% by mass of the initial weight.
US10227496B2
A composite conductive particle according to the present invention includes a first conductive particle having a particle diameter of greater than or equal to 0.1 μm and less than or equal to 50 μm; and a second conductive particle adhering to the surface of the first conductive particle and having a particle diameter of greater than or equal to 50 nm and less than or equal to 1000 nm, and the first conductive particle is composed of a first particle and a first metal coating covering the surface of the first particle, the second conductive particle is composed of a second particle and a second metal coating covering the surface of the second particle, a particle diameter of the first conductive particle is larger than a particle diameter of the second conductive particle, and an adhering rate of the second conductive particle.
US10227490B2
Embodiments herein relate to a composite material including about 10 to 80 wt. % of a polymer phase, the polymer phase comprising a thermoplastic polymer with a density of less than about 1.9 g-m−2; and about 20 to 90 wt. % of a dispersed mixed particulate phase, the dispersed mixed particulate phase comprising a mixed particulate and about 0.005 to 8 wt. % of a coating of at least one interfacial modifier. The mixed particulate including a portion of a reinforcing fiber and a portion of a particle. The composite material having a Young's modulus of greater than 700 MPa. In various embodiments, structural building components made from the composite are included as well as additive manufacturing components made from the composite.
US10227489B2
Disclosed are a thermoplastic resin composition including (A) about 100 parts by weight of a base resin including (A-1) about 65 wt % to about 85 wt % of a polycarbonate resin, (A-2) about 5 wt % to about 15 wt % of a polybutylene terephthalate resin, (A-3) about 5 wt % to about 20 wt % of a methyl methacrylate-styrene-acrylonitrile copolymer, and (A-4) greater than about 0 wt % and less than or equal to about 10 wt % of an aromatic vinyl compound-vinyl cyanide compound copolymer; and (B) about 5 parts by weight to about 10 parts by weight of a methyl methacrylate-butadiene-styrene copolymer, and a molded article using the same.
US10227481B2
The invention relates to a rubber composition having a good processability, and simultaneously having a rolling resistance performance and hardness after vulcanization at high levels, with which the contamination of the mold for processing due to the bleeding-out of the plasticizer can be suppressed, and in which the migration of the plasticizer and so on is suppressed to a low level; a vulcanized rubber obtained by vulcanizing the rubber composition; and to a tire including the rubber composition as at least a part thereof. The rubber composition contains 100 parts by mass of rubber component (A) composed of at least one of a synthetic rubber and a natural rubber, 0.1 to 50 parts by mass of a diene polymer (B), 20 to 150 parts by mass of a filler (C), 0.1 to 10 parts by mass of a vulcanizing agent (D), 0.1 to 15 parts by mass of a vulcanization accelerator (E) and 0.1 to 15 parts by mass of vulcanization aid (F).
US10227478B2
Disclosed is a resilient foam and methods of making the foam. The resilient foam includes a derivatized polyanionic polysaccharide and has an open-cell structure. When the resilient foam is contacted with water, the foam forms a thixotropic hydrogel.
US10227473B2
Propylene-ethylene random copolymers with improved long-term mechanical properties, especially improved impact strength retention, their manufacture as well as their use, e.g. for the production of moulded articles, particularly injection moulded articles, such as thin-walled plastic containers for packaging.
US10227471B2
A degradable polymer composite comprises a polyurethane comprising one or more of the following groups: ester groups; carbonate groups; or ether groups, in a backbone of the polyurethane; and about 1 to about 30 parts by weight of an acidic or basic powder comprising particles having an average size of about 5 microns to about 1 millimeter per 100 parts of the polyurethane.
US10227457B2
It is an object to provide a compound that can provide a molded article and a coating film excellent not only in solubility in an organic solvent, but also in miscibility with/dispersibility in a matrix resin, causing no aggregation in a matrix resin, excellent in surface modification property, and having high transparency. A fluorine-containing highly branched polymer obtained by polymerizing a monomer A having two or more radical polymerizable double bonds in the molecule thereof with a monomer B having a fluoroalkyl group and at least one radical polymerizable double bond in the molecule thereof in the presence of a polymerization initiator C in a content of 5% by mol or more and 200% by mol or less, based on the total molar amount of the monomer A and the monomer B; and a resin composition comprising the polymer.
US10227454B2
Disclosed herein are a phenyl-modified hybrid prepolymer, a phenyl-modified polydimethylsiloxane-based hybrid prepolymer, and a phenyl-modified polydimethylsiloxane-based hybrid polymer capable of controlling material hardness or surface tackiness depending on the intended use or purpose. A phenyl-modified hybrid prepolymer (B) is prepared by subjecting polydimethylsiloxane having trialkoxysilyl groups at both ends, phenyltrialkoxysilane, and diphenyldialkoxysilane to hydrolysis and condensation reaction. A phenyl-modified polydimethylsiloxane-based hybrid prepolymer (C) comprises (B), and is preferably prepared by mixing (B) and a phenyl-modified hybrid prepolymer (A) prepared by condensation reaction between polydimethylsiloxane having silanol groups at both ends and phenyltrialkoxysilane. The phenyl-modified polydimethylsiloxane-based hybrid polymer is obtained by heating and solidifying (C).
US10227449B2
A polymer includes a first structural unit represented by formula (1-1), (1-2) or (1-3) and a second structural unit represented by formula (2) or (3). In the formulae (1-1) to (1-3), (2) and (3), R1, R10 and R11 each represent a halogen atom, a monovalent hydrocarbon group having 1 to 20 carbon atoms, a monovalent halogenated hydrocarbon group having 1 to 20 carbon atoms, a nitro group or a cyano group; Zs each represent —O— or —S—; R4s each represent a methylene group or an alkylene group having 2 to 4 carbon atoms; and L represents a divalent group represented by formula (2-1). In the formula (2-1), Ra represents a divalent alicyclic hydrocarbon group having 5 to 30 ring atoms or a divalent fluorinated alicyclic hydrocarbon group having 5 to 30 ring atoms.
US10227447B2
Provided are: an antistatic agent and an antistatic agent composition which are capable of providing excellent antistatic effect in a small amount and have sufficient persistence and wiping resistance without impairing the intrinsic physical properties of a resin; and an antistatic resin composition and a molded article using the same.The antistatic agent includes a polymer compound (E) having a structure in which a diol, an aliphatic dicarboxylic acid, an aromatic dicarboxylic acid, a compound (B) which comprises at least one group represented by the following Formula (1) and has hydroxyl groups at both ends, and a polyhydric alcohol (D) having three or more hydroxyl groups are bound via ester bonds: —CH2—CH2—O— (1).
US10227439B2
A curable polyisocyanate composition comprising at least one or more polyisocyanate compounds, at least one or more trimerization catalyst compounds, at least one or more aldehyde compounds wherein the aldehyde compound is selected from compounds with the structure R—CHO wherein CHO is an aldehyde group and R is a hydrocarbyl group selected from an alkyl, alkenyl or aryl having 1-50 carbon atoms, preferably 1-20 carbon atoms, and at least one or more compounds selected from compounds which comprise a carboxamide group having the structure —CO—NH2 and/or from compounds which comprise a group having the structure —CO—NH—CO—.
US10227437B2
The present application provides the block copolymers and their application. The block copolymer has an excellent self assembling property and phase separation and various required functions can be freely applied thereto as necessary.
US10227436B2
The present application provides the block copolymers and their application. The block copolymer has an excellent self assembling property and phase separation and various required functions can be freely applied thereto as necessary.
US10227431B2
Binder compositions and methods for making and using same are provided. In at least one specific embodiment, the binder composition can include at least one unsaturated compound having two or more unsaturated carbon-carbon bonds and at least one free radical precursor. At least one of the unsaturated carbon-carbon bonds can be a pi-bond that is not conjugated with an aromatic moiety and can be capable of free radical addition. The free radical precursor can be present in an amount of about 7 wt % to about 99 wt %, based on the weight of the one or more unsaturated compounds.
US10227426B2
Antistatic polymers include divalent segments represented by the formula wherein R1 represents an alkyl group having from 6 to 18 carbon atoms, R2 and R3 represent alkyl groups having from 1 to 4 carbon atoms, and R4 represents an alkylene group having from 2 to 8 carbon atoms. Methods of making antistatic polymers are also disclosed.
US10227420B2
A method for preparation of decontaminated natural rubber is provided. The method is characterized in that it comprises a decontamination step in which wet natural rubber coagulum passes through a system comprising an extruder and a filter installed at the extruder outlet, the extruder comprising an axially symmetrical grooved sheath comprising in its thickness grooves opening on the inner surface of the sheath.
US10227417B2
It is intended to provide an antitumor drug having an excellent therapeutic effect, which is excellent in terms of antitumor effect and safety. There is provided an antibody-drug conjugate in which an antitumor compound represented by the following formula is conjugated to an anti-TROP2 antibody via a linker having a structure represented by the following formula: -L1-L2-LP-NH—(CH2)n1-La-(CH2)n2-C(═O)— wherein the anti-TROP2 antibody is connected to the terminal of L1, and the antitumor compound is connected to the carbonyl group of the —(CH2)n2-C(═O)— moiety with the nitrogen atom of the amino group at position 1 as a connecting position.
US10227416B2
The present invention relates generally to the fields of molecular biology and protein technology. More specifically, the invention concerns signal sequences for the secretion of heterologous polypeptide from bacteria. The invention also concerns recombinant polypeptides and uses thereof.
US10227415B2
Novel polypeptide combinations, polynucleotides encoding the polypeptides, and related compositions and methods are disclosed for zcytor17-containing multimeric or heterodimer cytokine receptors that may be used as novel cytokine antagonists, and within methods for detecting ligands that stimulate the proliferation and/or development of hematopoietic, lymphoid and myeloid cells in vitro and in vivo. The present invention also includes methods for producing the multimeric or heterodimeric cytokine receptor, uses therefor and antibodies thereto.
US10227414B2
Described herein are compositions and methods related to antigen binding proteins that bind to human ST2, including antibodies. In particular embodiments, the disclosure provides fully human anti-ST2 antibodies and deriviatives and variants thereof. Further provided are nucleic acids encoding such antibodies and antibody fragments, variants, and derivatives. Also, provided are methods of making and using such antibodies including methods of treating and preventing autoimmune and inflammatory disorders.
US10227410B2
The present invention is directed to heterodimeric antibodies that bind CD3 and PSMA.
US10227402B2
Antibodies and antibody fragments thereof with binding specificity to human Nerve Growth Factor (NGF) and methods of use for treating pain. Methods of treating pain or eliciting an analgesic effect comprising administering an effective amount of an anti-human NGF antibody or antibody fragment thereof, which inhibits the association of NGF with TrkA, and/or p75. These methods may optionally further comprising administering an effective amount of a second anti-human NGF antibody or fragment thereof (e.g., one which inhibits the association of NGF with p75, or one that inhibits the association of NGF with TrkA.)
US10227394B2
Disclosed are compositions and methods for accelerating wound closure and preventing inhibiting or reducing scarring or fibrosis. The methods of the present invention include administering to a person in need thereof an effective amount of a pharmaceutical composition comprising collagen 7 and/or one or more functional fragments or variants thereof. The functional fragments generally comprise at least one of the nine Fibronectin Type III-like Region of the NC1 region of collagen 7.
US10227389B2
Variant IL-13 polypeptides are provided, which are engineered to have one or more of the following properties: (a) altered affinity for IL-13Rα2, relative to the native human IL-13 protein; (b) altered affinity for IL-13Rα1 relative to the native human IL-13 protein; (c) a disruption in the binding site for IL-4Rα relative to the native human IL-13 protein.
US10227386B2
Disclosed is a recombinant polypeptide for facilitating membrane fusion. The recombinant polypeptide having a sequence with at least 80% sequence identity with the ectodomain of p14 fusion-associated small transmembrane (FAST) protein and having a functional myristoylation motif, a transmembrane domain from a FAST protein and a sequence with at least 80% sequence identity with the endodomain of p15 FAST protein. A targeting ligand can be added to the recombinant polypeptide for selective fusion. The recombinant polypeptide can be included in the membrane of a liposome, or the like, to facilitate the delivery of bioactive compounds, such as siRNA, or the recombinant polypeptide can be mixed with a lipid carrier and added to cultured cells to induce cell-cell fusion and heterokaryon formation.
US10227380B2
Provided herein are peptidomimetic macrocycles and methods of using such macrocycles for the treatment of disease.
US10227378B2
The present invention pertains to a method for loading a crystallization device and for manufacturing a crystallization device comprising multiple receptacles with a pre-defined amount of at least one matrix-forming compound capable of forming a crystallization matrix for a membrane protein, said method comprising the following steps: a) Modifying the state of aggregation of said at least one matrix-forming compound to a fluidic state which allows dispensing said at least one matrix-forming compound, and b) dispensing a defined amount of said at least one matrix-forming compound into at least one receptacle of the crystallization device, wherein said dispensed matrix-forming compound solidifies within said receptacle. Thereby prefilled crystallization devices are obtained which can be used as consumables in particular in automated crystallization processes. Also provided are protein crystallization methods using respectively prepared crystallization devices.
US10227370B2
The present disclosure provides for methods and compositions comprising a series of synthetic glycopolymers. The disclosure also relates to a kit which is suitable for carrying out the inventive methods.
US10227366B2
The present invention relates to novel bis-iridium-based Ir(III) complexes, labels manufactured using these complexes and a method for producing such complexes.
US10227359B2
The present disclosure relates to tricyclic heterocycles which are inhibitors of BET proteins such as BRD2, BRD3, BRD4, and BRD-t and are useful in the treatment of diseases such as cancer.
US10227357B2
Compounds active on c-kit protein kinases or mutant c-kit protein kinases having any mutations are described, as well as methods of making and using such compounds to treat diseases and conditions associated with aberrant activity of the c-kit protein kinases and mutant c-kit protein kinases.
US10227356B2
Compounds that inhibit CNKSR1, pharmaceutical compositions including compounds that inhibit CNKSR1 and methods of treating disease or disorders that respond to CNKSR1 inhibition are described herein. Additionally, methods of identifying inhibitors of CNKSR1 are described.
US10227354B2
Synthetic methods are provided for preparation of oxycodone and salts thereof with an improved impurity profile. Thebaine is converted to 14-hydroxycodeinone sulfate intermediate to minimize a 7,8-dihydro-8,14-dihydroxycodeinone impurity. Efficient methods for conversion of oxycodone base to oxycodone hydrochloride are provided to minimize 14-hydroxycodeinone impurity in the final product.
US10227353B2
Methods that may be used for the manufacture of a class of chemical compounds known as morphinans, including neopine, are provided. Compositions useful for the synthesis of morphinans, including neopine, are also provided.
US10227352B2
Disclosed are new small molecules having a 4-methylpyrrrolo[1,2-a]pyrimidine-8-carboxamide core structure and the uses thereof for modulating glucocerebrosidase activity. Also disclosed are pharmaceutical compositions comprising the small molecules which may be administered in methods of treating diseases or disorders associated with glucocerebrosidase activity, including neurological diseases and disorders such as Gaucher's disease and Parkinson's disease. The small molecules may contain a fluorophore or may be conjugated to a fluorophore in order to prepare a fluorescent probe for use in high throughput screening methods to identify new modulators of glucocerebrosidase activity via fluorescence polarization.
US10227348B2
Use of 10H-benzo[g]pteridine-2,4-dione derivatives as photosensitizers in the inactivation of microorganisms.
US10227335B2
Provided herein are processes for forming sufentanil citrate from sufentanil base. One process comprises forming sufentanil citrate in the presence of a polar non-aqueous solvent. Other processes comprise forming sufentanil citrate in the presence of water.
US10227330B2
The present invention provides a diaminopyrimidine derivative or its pharmaceutically acceptable salt, a process for the preparation thereof, a pharmaceutical composition comprising the same, and a use thereof. The diaminopyrimidine derivative or its pharmaceutically acceptable salt functions as a 5-HT4 receptor agonist, and therefore can be usefully applied for preventing or treating dysfunction in gastrointestinal motility, one of the gastrointestinal diseases, such as gastroesophageal reflux disease (GERD), constipation, irritable bowel syndrome (IBS), dyspepsia, post-operative ileus, delayed gastric emptying, gastroparesis, intestinal pseudo-obstruction, drug-induced delayed transit, or diabetic gastric atony.
US10227329B2
Described herein are compounds that inhibit wild-type RET and its resistant mutants, pharmaceutical compositions including such compounds, and methods of using such compounds and compositions.
US10227327B2
Compounds according to formula I are provided: A-L-B wherein A represents a lipophilic chelating moiety which is selective for Zn2+ ions; L is a covalent bond or a linker; and B is a vector which is either a moiety capable of interacting with one or more biological structures found in a bacterium (preferably in a bacterial cell wall), for example a penicillin-binding protein such as a metallo-β-lactamase or DD-transferase, or a moiety capable of enhancing transport of the compound across a bacterial cell membrane. A method of treating and/or preventing a bacterial infection in a human or non-human mammal employing such compounds are also provided. In such a method, the compound of formula I may be administered in combination with (either simultaneously, separately, or sequentially) a β-lactam antibiotic.
US10227323B2
Described herein are compounds of Formula I, methods of making such compounds, pharmaceutical compositions and medicaments containing such compounds, and methods of using such compounds to treat or prevent diseases or conditions associated with the enzyme glucosylceramide synthase (GCS).
US10227322B2
Process for increasingly producing D-Lactide and meso lactide by depolymerizing by back biting polylactide (PLA) said process which comprises: (i) Depolymerizing polylactide into its corresponding dimeric cyclic esters by heating the polylactide in the presence of a catalyst system comprising a catalyst and a co-catalyst in a reaction zone at temperature and pressure at which the polylactide is molten; (ii) Forming a vapor product stream from the reaction zone; (iii) Removing the vapor product stream and optionally condense it; (iv) Recovering, either together or separately meso-lactide, D-lactide and L-lactide.
US10227321B2
The invention relates to a compound of general formula (I) (in configuration Z or E) and to pro-pheromonal compositions and formulations comprising said compound, in addition to the uses thereof for soothing purposes for non-human mammals such as sheep, pigs, sheep, cattle, felines, equines and canines.
US10227318B2
Provided is a method for producing γ-valerolactone that is hard to elute metallic components and has high productivity. γ-Valerolactone is synthesized by bringing a levulinic acid compound represented by the formula (1) (where R represents a hydrogen atom, a linear alkyl group of 1 to 6 carbon atoms or a branched alkyl group of 3 to 6 carbon atoms) into contact with hydrogen in the presence of a catalyst in which two or more different kinds of metals of Group VIII to Group X metals in the periodic table are supported on a support.
US10227312B2
Described herein are compounds of Formula I, methods of making such compounds, pharmaceutical compositions and medicaments containing such compounds, and methods of using such compounds to treat or prevent diseases or conditions associated with the enzyme glucosylceramide synthase (GCS).
US10227307B2
Described herein are compounds of Formula (I), pharmaceutically acceptable salts thereof, and pharmaceutical compositions thereof. Compounds described herein are useful for inhibiting PRMT1 activity. Methods of using the compounds for treating PRMT1-mediated disorders are also described.
US10227306B2
Disclosed are novel compounds of specific chemical structures having inhibitory activity on c-Myc/Max/DNA complex formation or pharmaceutically acceptable salts thereof.
US10227305B2
The present invention relates to a process for preparing indacaterol or salts thereof. The process comprises of forming compound of Formula 1 by reacting compound of Formula 2 and compound of Formula 3 in the presence of a solvent to Form compound of Formula 4, which on removal of the protecting groups forms compound of Formula 1.
US10227302B2
What is described is a compound wherein R1 and R2 are the same or different, each a linear or branched alkyl consisting of 1 to 20 carbons, or a linear or branched alkenyl or alkynyl consisting of 2 to 20 carbons; L1 and L2 are the same or different, each a bond, a linear alkylene of 1-18 carbons, or a linear alkenylene consisting of 2 to 18 carbons; L3 is a bond or a linear or branched alkylene consisting of 1 to 6 carbons; L4 is a bond or a methylene; X is S or O, R3 is a linear or branched alkylene consisting of 1 to 6 carbons, and R4 and R5 are the same or different, each a hydrogen or a linear or branched alkyl consisting of 1 to 6 carbons; or a pharmaceutically acceptable salt thereof.
US10227301B2
The invention relates to the compounds of formula I, formula II, formula III, formula IV and formula V or its pharmaceutical acceptable polymorphs, solvates, enantiomers, stereoisomers and hydrates thereof. The pharmaceutical compositions comprising an effective amount of compounds of formula I, formula II, formula III, formula IV or formula V and methods for the treatment of inflammation and pain may be formulated for oral, buccal, rectal, topical, transdermal, transmucosal, intravenous, oral solution, buccal mucosal layer tablet, parenteral administration, syrup, or injection. Such compositions may be used to treatment of pain, oral mucosal inflammatory or oral infectious diseases.
US10227297B2
Disclosed are pulverulent compositions of a complex between an acid and a metal, having a high organosulfur compound content, and method for preparing same.
US10227294B2
The invention relates to a method for preparing an aromatic polyisocyanate in an isocyanate plant comprising a reaction section for a phosgenation reaction, wherein a primary aromatic amine is reacted with phosgene compounds in a reaction section to obtain an isocyanate comprising reaction product and wherein CO2 concentration in the gases coming from the reaction section is measured and analyzed, and wherein the conditions in the phosgenation reaction are adjusted in case the CO2 concentration in the gases coming from the reaction section is higher than a background CO2 concentration.
US10227293B2
The present invention relates to a method for preparing a citalopram diol represented by formula IV, comprising the following steps: in the existence of an auxiliary reagent of metal salt, allowing 5-cyanophthalide to sequentially subjected to Grignard addition reactions with p-fluorophenyl magnesium halide and N, N-dimethylaminopropyl magnesium halide in an organic solvent; and after the reactions are completed, performing hydrolysis and separation to obtain citalopram diol represented by formula IV. In the present invention, by adding an auxiliary reagent of metal salt, the activity and the selectivity of the Grignard reactions are remarkably improved, and the reaction yield is obviously enhanced.
US10227290B2
Provided herein are sphingolipid compounds that are useful for activating natural killer T cells. Also provided are methods for treating or preventing a disease or disorder that is treatable by activating the immune system by stimulating natural killer T cells. The compounds are therefore useful for treating or reducing the likelihood of occurrence of an immune diseases and disorders, such as autoimmune diseases or disorders. The compounds may also be used for treating or reducing the likelihood of occurrence of a microbial infection or for treating or reducing the likelihood of occurrence of a cancer in a subject by administering the sphingolipid compounds described herein.
US10227281B2
A composition comprising a compound of formula (Va) wherein n is 1 or 2 and wherein m is 1 or 2, with n and m preferably both being 1 or both being 2, more preferably both being 1, and/or, preferably and, a compound of formula, wherein n is 1 or 2 and wherein m is 1 or 2, with n and m preferably both being 1 or both being 2, more preferably both being 1, and wherein at least 90 weight-% of the composition consist of compounds of formula (Va) and formula (Vb).
US10227270B2
Provided are a separation method for easily recovering normal butene from an olefin fraction including isobutene, isobutane, 1-butene, 2-butene, and normal butane, and a separation process system using the method. Since the separation method according to the present invention may easily convert 1-butene included in the olefin fraction to 2-butene, normal butene may be effectively separated and recovered by factional distillation and each recovered fraction may be easily refluxed even if the use of a reflux system using a refrigerant is reduced or excluded. Thus, economic efficiency may be improved and simultaneously, separation efficiency may be increased.
US10227265B2
Disclosed is a method of making a granulate of a urea product comprising urea and a salt, such as urea ammonium sulfate, having a high content of the salt. The high content is such as to provide an amount of the salt above the limit of solubility of the salt in urea. The granulate of the invention is characterized by having a smooth surface, which, e.g. in the event of urea ammonium sulfate, is not normally the case for granulate having the aforementioned high ammonium sulfate content. According to the invention this is realized by dividing the feed liquids to granulation. This division is based on non-final granulation liquids of a sufficiently high content of the salt, and a final granulation liquid (determining the surface) having a salt content of below the solubility limit of the salt, or no salt at all. E.g. in the event of urea ammonium sulfate, the non-final granulation liquids possibly are a slurry of urea and more than 20 wt. % of ammonium sulfate. The final granulation liquid then has 0-20 wt. % of ammonium sulfate, i.e. below the solubility limit.
US10227262B2
A thermal barrier coating for a turbine engine component contains neodymia, optionally alumina, and zirconia. The thermal barrier coating has resistance to CMAS attack and a low thermal conductivity.
US10227257B2
The invention provides a binder composition comprising: (a) ground granulated blast furnace slag (GGBS), (b) basic oxygen slag (BOS), and (c) an alkaline inorganic waste material selected from by-pass dust (BPD), cement kiln dust (CKD), and mixtures thereof. The use of such a composition as a binder in a concrete mix, concrete mixes comprising such a composition, methods of manufacturing concrete articles, and concrete articles such as paving blocks are also provided.
US10227253B2
A method of strengthening an alkali aluminoborosilicate glass. A compressive layer extending from a surface of the glass to a depth of layer is formed by exchanging larger metal cations for smaller metal cations present in the glass. In a second step, metal cations in the glass are exchanged for larger metal cations to a second depth in the glass that is less than the depth of layer and increase the compressive stress of the compressive layer. Formation of the compressive layer and replacement of cations with larger cations can be achieved by a two-step ion exchange process. An alkali aluminoborosilicate glass having a compressive layer and a crack indentation threshold of at least 3000 gf is also provided.
US10227252B2
Disclosed is a method for the production of a tube having, in sections, a non-circular profile by deforming, comprising: a) providing a tube, which has a circular initial profile; b) conveying the tube in a hot, malleable state through a nip, which is formed by squeezing rollers and has a first nip width, which is larger than or equal to an outer dimension of the initial profile; c) adjusting the squeezing rollers for setting a second nip width, which is smaller than the outer dimension of the initial profile, and deforming the initial profile in said hot, malleable state for obtaining said non-circular cross section; and d) adjusting the squeezing rollers for setting a third nip width, which is larger than or equal to the outer dimension of the initial profile, and severing said tube in a region having a circular cross section; so that respective end portions of said tube have a circular cross section According to the invention, the tubes can be connected reliably with connecting-members or other tubes via the end portions having the circular profile using proven tube connection technologies. At the same time there is at least one central section having a non-circular cross section which is of advantage, for example for applications in photobioreactors.
US10227249B2
The present invention relates to mixing apparatus for crushing sludge comprising a motor part in which a rotary shaft is inserted into the motor part and the motor part is rotated, a moving part formed to penetrate the motor part from one side to another side and move a chemical which is flowed through an outside chemical feeder to the another side, and a paddle mounted on the another side of the motor part to rotate based on the rotation of the motor part and spray the chemical.
US10227245B2
A system and method for applying an advanced oxidation process to a UV fluid reactor. An L-shaped electrode is connected to a UV reactor hatch and inserted into the reactor upstream from a UV radiation source.
US10227244B2
A fast acting water purification system containing a source of silver ions which is suitable for use in personal or household water containers, where the non-potable water may contain halides or other materials that limit the solubility of silver in the non-potable water, with the purification agent including a source of silver ions and a compound containing a hydantoin ring increase the presence of silver ions in the non-potable water to a level sufficient to quickly kill harmful microorganisms in the non-potable water without the need to add additional biocides to the non-potable water or pretreat the non-potable water.
US10227240B2
A system may include a catch tray coupled with a flow distributor. A mesh screen and carriage may be positioned within the catch tray. A drive bar may be coupled with the carriage and a pitman arm. A gear box may be coupled with a motor and the pitman arm. A process may include distributing contaminated fluid onto the mesh screen. A screen plane of the mesh screen may be at a screen angle that is oblique relative to the direction of the force of gravity. The screen plane is defined by a top surface of the mesh screen. The process may include moving the carriage in a reciprocating linear motion by rotating the pitman arm, and spraying a liquid onto the mesh screen. Liquid may flow through the mesh screen forming clarified liquid, and contaminate may move along the top of the mesh screen to a contaminate outlet.
US10227231B2
The present disclosure relates to a wafer-level package that includes a first thinned die, a multilayer redistribution structure, a first mold compound, and a second mold compound. The first thinned die resides over a top surface of the multilayer redistribution structure. The multilayer redistribution structure includes at least one support pad that is on a bottom surface of the multilayer redistribution structure and vertically aligned with the first thinned die. The first mold compound resides over the multilayer redistribution structure and around the first thinned die, and extends beyond a top surface of the first thinned die to define an opening within the first mold compound and over the first thinned die. The second mold compound fills the opening and is in contact with the top surface of the first thinned die.
US10227229B2
A headrest in which a pad layer is integrally formed, including a portion with a narrow gap, between a mechanism having various types of incorporated functions and a skin member. A shock absorbing member that is an injection-passage-forming member having a foaming raw material injection passage formed so as to run substantially along a direction that is the vertical direction of the headrest in orientation of when a seat is attached, is set in the inside of a skin member, and a foaming raw material for forming the pad layer is injected through the foaming raw material injection passage. The configuration preferably causes the foaming raw material to spread by the foaming start time, as the foaming raw material spreads to the outer side of the headrest, that is, to the inner surface of the skin member, where the pad layer is required to be formed.
US10227220B2
Methods and apparatus for constructing refractory structures, e.g., glass furnace regenerator structures and/or glass furnace structures having walls formed of refractory block and buck stays externally supporting the walls are provided. Opposed pairs of supports are connected to at least a respective one of the vertically oriented buck stays with cross-support beams spanning the refractory structure between a respective pair of the supports. An overhead crane assembly is supported by the cross-support beams. In such a manner, refractory components of the refractory structure (e.g., refractory wall blocks and/or refractory checker bricks) may be installed using the overhead crane assembly.
US10227208B2
A safety apparatus for elevator apparatuses which can move a cab via a drive including a monitoring unit for monitoring at least one of the drive and/or the motor regulation system of the drive, a safety device having at least two sensors, which can be switched between at least two switching states depending on a state, in particular a closing state. In order to be able to reduce operating costs, at least one of the safety device and the monitoring unit includes a controller, which is designed to identify the respective switching states of the sensors, and to transmit at least one of data and monitoring signals to the monitoring unit.
US10227205B2
A reel assembly includes a housing, an axle within the housing, a reel within the housing, a first spring and a second spring. The housing has a fixed connection portion. The fixed connection portion is fixed from rotation relative to the housing. The axle is configured to rotate about an axis of rotation. The reel is configured to rotate about the axis of rotation and the axle. The first spring is coupled between the axle and the fixed connection portion of the housing. The second spring is coupled between the axle and the reel. The second spring has a torque profile associated therewith different from a torque profile of the first spring. Rotation of the reel relative to the housing in a direction tending to tension the second spring transmits rotational movement to the axle through the tensioning of the second spring. Such rotational movement of the axle is applied to the first spring to tension the first spring.
US10227201B2
Presently disclosed embodiments are directed to a system and method for loading mail trays in a sorter without human intervention. Specifically, the disclosed embodiments utilize an automated mail tray having a bottom plate that is selectively moveable between an elevated position and a lowered position. The automated mail tray may be positioned on a shelf under a corresponding output pocket of a mail stacker, and the bottom plate may be elevated to receive mail product transferred from the output pocket to the automated mail tray. After receiving the mail product on the elevated bottom plate, the bottom plate of the mail tray may be lowered so that the mail product is transferred from the output pocket to a position fully situated in the automated mail tray. The mail tray filled with mail product may then be removed from the shelf and replaced with an empty automated mail tray.
US10227197B2
A method for reducing the effects of variations in an unwinding, convolutely wound roll of web material is disclosed. The method utilizes the steps of: a. selecting a reference objective relating to a downstream operation, b. choosing at least one feedback device correlated to the reference objective, c. collecting process data from the at least one feedback device at different positions within a time-varying operation cycle for at least one operation cycle at a learning speed, d. calculating an error as the difference between the collected process data from step (c) and a reference signal related to the selected reference objective, e. generating a correction signal based upon the calculated error from step (d) and, f. applying the correction signal to the actuator during a succeeding time-varying operation cycle.
US10227192B2
An image forming apparatus including: a sheet feeding tray configured to support a sheet; and an apparatus main body configured to support the sheet feeding tray so as to be moveable in a direction parallel with a sheet feeding direction, the apparatus main body including a chute configured to guide the sheet that is fed from the sheet feeding tray, wherein the sheet feeding tray includes a guiding member configured to be displaced between an engaging position at which the guiding member engages with the chute and restrains movement of the sheet feeding tray and a separation position at which the guiding member separates from the chute and permits movement of the sheet feeding tray, and wherein the guiding member is configured to guide the sheet that is fed from the sheet feeding tray toward the chute when the guiding member is located at the engaging position.
US10227181B2
A conveyor (1) has rollers (12) for conveying a load (100) along a conveying direction (C). A stop (20) is configured to be arranged in a separating configuration, in which the load (100) is impeded from being conveyed along the conveying direction (C), and a conveying configuration, in which the load (100) can be conveyed along the conveying direction (C). A trigger (30) is configured to move between a triggered position and an idle position. The trigger (30) is configured so that the load (100) moving in the conveying direction (C) onto the trigger (30) moves the trigger (30) out of the idle position and into the triggered position, thereby arranging the stop (20) in the separating configuration. A counter element (50) is configured to move the trigger (30) out of the idle position when the load (100) is conveyed on the rollers (12) against the conveying direction (C).
US10227180B2
A robotic placement machine including a base operably connected to the Y axis actuator and the X axis actuator, a first Z axis actuator coupled to the first end of the base, the first Z axis actuator capable of moving up and down a first Z axis, a second Z axis actuator coupled to the second end of the base, the second Z axis actuator capable of moving up and down a second Z axis, and a pick and place plate operably connected to the first Z axis actuator and the second Z axis actuator, wherein the first Z axis actuator and the second Z axis actuator are each capable of moving independently of each other to tilt the pick and place plate is provided. Furthermore, a system comprising a first machine, second machine, and third machine to eliminate air bubbles when bonding two substrates is also provided. A method of optical bonding is further provided.
US10227177B2
An autonomous transport vehicle including a transfer arm including at least one finger and a movable finger support member, at least one sensor configured to detect movement of the at least one finger, the at least one sensor having a registration member and a detection member where one of the registration member and detection member is mounted to each of the at least one finger so as to be movable with a respective one of the at least one finger and the other one of the registration member and detection member is stationary relative to the at least one finger, and a controller in communication with the at least one sensor, the controller being configured to determine a position of the at least one finger along the second direction based on a proximity of the registration member relative to the detection member.
US10227171B2
The present disclosure relates generally to systems and methods for creating protective packaging. A device comprises a processor and a memory. The memory contains computer readable instructions that, when executed by the processor, cause the processor to receive, from an external sensor, data that is indicative of physical characteristics for an object to be packaged, determine a type of object to which the object to be packaged corresponds based on the physical characteristics, select one or more type of packaging elements for packaging the object based on the type of object, and cause a packaging machine to create packaging elements of the selected type.
US10227167B2
A dispensing assembly for a liquid container including a ring part configured to be mounted to a liquid container, a resilient member positioned in the ring part to be in contact with the liquid contents of the liquid container, a ring member mountable to the ring part to secure the resilient member to the ring part, and a hollow connecting member with an outlet. The connecting member is releasably securable to the ring member and includes a hollow projecting member which, when the connecting member is secured to the ring member, engages the resilient member so as to urge an opening in the resilient member to permit liquid in the container to pass into the connecting member and subsequently out through the outlet.
US10227159B2
A container (10) comprises a base (12), upstanding walls (14) on the base and a lid arrangement (16) pivotally attacked to at least one of the walls at a hinge (17). The lid arrangement is pivotally moveable about the hinge from an open position to a closed position. When the lid arrangement (16) is in the open position, the container (10) can be nested within a similar further container having a similar further lid arrangement, and the lid arrangement (16) can be received within the further lid arrangement in a nested condition of the lid arrangements.
US10227157B2
A plastic egg carton having features that enable aligning and stacking of multiple cartons for transport, and providing easy-to-view print and labeling areas in multiple directions. In one embodiment, the egg carton has a unique lid including a flat diagonal stacking panel (also referred to as a diagonal lid panel) that extends between two opposing corners of the rectangular shaped carton. The top wall of the diagonal lid panel can receive labeling or printing. The diagonal lid panel also includes a sidewall extending downwardly from the top wall toward a bottom perimeter edge of the lid, the sidewall having at each of the two opposing corners at least one flat side panel that can also receive printing or labeling. In one embodiment, each of the opposing corners includes a rounded corner portion and two flat side panels disposed on either side of the rounded corner, thus providing a total of four side viewing areas (each in a different direction) for labeling or printing, enabling the consumer to view information such as egg size, date, nutritional information, retail information, or UPC labels.
US10227153B2
Medicine packaging apparatuses and methods for accurately determining a remaining sheet amount of a medicine packaging sheet are described. The apparatus includes: a roll support section to which a core tube of a medicine packaging sheet roll is attached; a sensor disposed in the roll support section for outputting a count value according to a rotation amount; a wireless reader-writer unit for writing information to a core tube IC tag and reading said information; an information generation section for generating information to be written to the core tube IC tag; a remaining sheet amount estimation section for estimating a current amount of remaining sheet based on the information and dimensional information of the core tube; and a controller which selectively performs an operation if a reference time-point count value is not yet written to the core tube IC tag and another operation if the count value is already written thereto.
US10227148B2
A method of combining groups of articles to form packaging units includes wrapping a packaging unit along a running direction thereof on a transporting path with a sheet material, concurrently with the wrapping, forming a sheet-material overlap and folding flaps that each project beyond the packaging unit along transverse peripheries thereof, positioning the folding flaps against the packaging unit as the packaging unit passes through a folding unit, and fixing the folding flaps to each other, thereby forming a sheet-material wrapper that is closed on all sides.
US10227145B2
A spacecraft includes a 3-D closed truss structure including at least four coupling nodes and at least six strut elements, attached together by a plurality of joints, each coupling node including at least two legs, each strut element disposed between and attached with a respective pair of the plurality of coupling nodes. Each coupling node is attached, at respective ones of the plurality of joints, with at least two strut elements. Each strut element is attached at a first end with a first leg of a first coupling node and is attached at a second end with a second leg of a second coupling node, the first leg being substantially longer than the second leg.
US10227143B2
Described herein is a system that includes an actuator with a movable input, a first summing mechanism with an input, a first output, and a second output. The input of the first summing mechanism is movably driven by the movable input of the actuator and the first output of the first summing mechanism is movably coupled to a first actuatable element. The system also includes an end mechanism with an input and a first output. The input of the end mechanism is movably driven by the second output and the first output of the end mechanism is movably coupled to a second actuatable element. The system further includes a sensor that senses a position of the rotational input of the actuator. A status of the first and second actuatable elements is based on a sensed position of the movable input of the actuator.
US10227142B1
A vehicle, includes a vehicle and a strain gauge. The vehicle includes a vehicle body component exposed to an exterior of the vehicle. The strain gauge is coupled with the vehicle body component.
US10227140B2
A method detects an impendent situation of an operating aircraft. The method comprises receiving data corresponding to a plurality of parameters related to an operation of the aircraft. It is determined if any of the plurality of parameters is at or beyond at least a first respective threshold by comparing the plurality of parameters with the first respective thresholds. If at least one of the parameters is an outlier parameter at or beyond its first respective threshold, another or others of the plurality of parameters associated to the at least one outlier parameter is identified, the at least one other parameter being selected based on a predetermined combination of parameters representative of an adverse condition. The associated parameters are compared with a stored data combination threshold specific to the associated parameters. A signal indicative of an impending situation is output if the associated parameters are on or beyond the data combination threshold. A system and an aircraft detecting an impendent situation are also provided.
US10227135B1
A redundant clustered parachute apparatus includes a harness and a plurality of lines operatively coupled to the harness. Each line has a length and a plurality of canopies coupled to and along the length. The plurality of canopies, across the plurality of lines, create an aggregated force of air resistance to slow a falling object in the harness. Loss of some of the canopies or some of the lines does not significantly affect the performance of the redundant clustered parachute apparatus to safely deliver the object to the ground.
US10227121B2
A propulsion system (102) for an aquatic vessel (100) is provided. The propulsion system includes a plurality of Magnus-type rotors (108) and a drive arrangement (147) for rotating the plurality of Magnus-type rotors. The plurality of Magnus-type rotors are operable to rotate about corresponding substantially upright axes. The propulsion system also includes a control arrangement (150) for controlling the drive arrangement to vary rates of rotations of the plurality of Magnus-type rotors. Each of the plurality of Magnus-type rotors includes a hollow region (116) therein. Each of the Magnus-type rotors is rotationally supported onto a support arrangement (118) which extends into the hollow region. The drive arrangement includes at least one motor (148) disposed in the hollow region and located outside the support arrangement such that the at least one motor is accessible for maintenance. Furthermore, the at least one Magnus-type rotor includes a ventilation aperture arrangement (132) for enabling an upward movement of air to occur in operation within the at least one Magnus-type rotor for ventilating and cooling the drive arrangement and/or other internal components.
US10227119B2
Systems and methods are described where odometry information that is obtained from a video camera mounted on an underwater vehicle is used to estimate the velocity of the underwater vehicle. The techniques described herein estimate the velocity of the underwater vehicle passively without emitting sound or other energy from the underwater vehicle.
US10227118B2
A buoyant apparatus and method of use buoyancy to offset the weight of a load during immersion of the load in a fluid medium such as a payload manipulated by a cable and crane or by a remotely operated undersea vehicle. Buoyancy modules that can be of different size and shape have elongated supports that are attachable via complementary connection fixtures at the ends. The attached supports form a skeleton of the array. The connection fixtures are axially resiliently compressible and maintain the buoyancy modules in abutment notwithstanding shrinkage or expansion of the buoyant material due to hydrostatic pressure that increases with depth.
US10227108B2
Apparatus and methods to couple fuel components to a fuel tank are described. An example method includes coupling a carrier to a guide suspended in a cavity of a fuel tank, where the guide extends in a longitudinal direction between a first end of the guide adjacent a first side wall of the fuel tank and a second end of the guide adjacent a second side wall of the fuel tank opposite the first side wall, and moving the carrier along the guide between the first end of the guide and the second end of the guide.
US10227107B1
A method and tool provide for removal of a rear bicycle wheel of a bicycle having a rear derailleur. A securing device maintains the tool in a fixed position with respect to the bicycle. A chain disengagement element is moveably attached to the securing device whereby moving the chain disengagement element moves a portion of the chain away from an axel mounted gear cassette sufficiently to completely disengage the chain from the axel mounted cassette. This allows for easy removal of the wheel.
US10227106B2
A bicycle controller and bicycle drive device that improves the stability of the behavior of a bicycle. The bicycle controller includes an electronic control unit that reduces the output of a motor, which is configured to assist in propulsion of the bicycle, in accordance with an angular acceleration of a rotary body. The rotary body is included in a human power transmission path extending from an input for human power to a coupling portion coupled to a drive wheel.
US10227098B2
A transporter for transporting a load over a surface. The transporter includes a support platform for supporting the load. The support platform is characterized by a fore-aft axis, a lateral axis, and an orientation with respect to the surface, the orientation referred to as an attitude. At least one ground-contacting element is flexibly coupled to the support platform in such a manner that the attitude of the support platform is capable of variation. One or more ground-contacting elements are driven by a motorized drive arrangement. A sensor module generates a signal characterizing the attitude of the support platform. Based on the attitude, a controller commands the motorized drive arrangement.
US10227095B2
A vehicle having one or more guide vanes each disposed at each of a respective front and/or rear quarter of the vehicle for guiding the airflow in the vicinity of an adjacent wheel of the vehicle.
US10227092B2
A flap assembly for a motor vehicle includes a front flap which closes an assembly space of the motor vehicle and can be pivoted between a closed state and an open state. The front flap has a flap wall which, in the closed state of the front flap, extends substantially in a vehicle vertical direction, and the assembly space has an assembly space wall. The flap wall and the assembly space wall are designed to be located opposite each other in the closed state of the front flap. They form a sealing action in order to prevent entry of contaminants into the assembly space.
US10227091B2
A method is provided for accident prevention with the following traffic during an automated parking procedure of a motor vehicle having a parking assistance system with at least one automated transverse guide. In order to park, a first parking movement into the transverse parking space is provided in the backwards or forwards direction, and, if necessary, at least one subsequent correction movement in the forwards or backwards direction. A need for a correction movement in the forward or backward direction is determined according to the method. In response to the fact that a need for a correction movement is determined, the method prevents the vehicle from pulling so far into the transverse parking space during the parking movement so that afterwards, when beginning the correction movement in the forward or backward direction, the driver does not have an obstructed view of the following traffic due to the visual blocking by a vehicle adjacent to the transverse parking space.
US10227088B2
A method for managing a power steering system, including a step (a) of detecting a reversal in the steering direction which involves acquiring a signal, referred to as a “motor torque signal” (CMot), representative of the assistance force (Cassist) delivered by the power steering motor, then evaluating the time derivative (δCMot/δt) of the motor torque signal, then comparing the time derivative of the motor torque signal to a predefined variation threshold (Spic) in order to detect a derivative peak, greater than the variation threshold (Spic), that indicates a reversal in the steering direction. The method next includes a friction evaluation step (b) which involves evaluating the friction from the drop, during the reversal in the steering direction, in a so-called “actuation force signal” (Caction), which is representative of the total actuation force exerted together on the power steering by the driver and by the power steering motor.
US10227087B2
A steering control device that can set and cancel an automatic driving mode includes a steering control unit, a cancellation instruction detection unit, a stop detection unit, and a steering angle reduction unit. The steering control unit controls a steering angle in the automatic driving mode so that a vehicle travels along an intended route. The cancellation instruction detection unit detects a cancellation instruction to cancel the automatic driving mode. The stop detection unit detects a stop of the vehicle. The steering angle reduction unit reduces the steering angle set by the steering control unit, if the cancellation instruction detection unit detects the cancellation instruction and the stop detection unit detects the stop of the vehicle.
US10227085B2
A rotary electrical machine control apparatus is provided which controls drive of a rotary electrical machine having a plurality of winding sets. The apparatus includes inverters that are provided so as to respectively correspond to the winding sets, a temperature detection element that detects a base element that is used as a base for estimation of inverter temperatures, which are temperatures of the inverters, and a control section that has a temperature estimation section that estimates the inverter temperatures based on the base temperature and a temperature change amount generated due to current application to the inverters. On-resistance of the switching elements of the first inverter is smaller than on-resistance of the switching elements of the second inverter. The temperature detection element is disposed in an area, a distance between the area and the first inverter being shorter than a distance between the area and the second inverter.
US10227081B2
Exemplary embodiments are directed to pool cleaners that remove debris from water using a plurality of cyclonic flows, or that include a removable impeller subassembly, a check valve for a debris canister, a particle separator assembly having a handle that locks to the pool cleaner, a modular roller drive gear box, or a roller latch that secures a roller to the pool cleaner. Exemplary embodiments are also directed to the check valve and the roller latch themselves. Exemplary embodiments are directed to a filter medium for pool cleaners that includes embossments providing flow channels for water, and to roller assemblies for pool cleaners. Exemplary embodiments are directed to pool cleaners including alternative pump motor engagements. Exemplary embodiments are directed to pool cleaners power supplies that include a potted and contoured power board assembly, and to kickstands therefor. Exemplary embodiments are directed to a pool cleaner caddy, and removable wheels therefor.
US10227078B2
A luggage cart assembly including multiple luggage containers which are vertically arranged, and one or more of the containers are pivotable such that the container can be accessed without having to move the other containers, where the container includes first and second attachment members to attach the container to the luggage cart. When the first attachment member is detached from the luggage cart and the second attachment member remains attached to the luggage cart, the container is pivotable relative to luggage cart and the container is supported by the second attachment member. The first and second containers may be vertically separated from one another in some embodiments.
US10227067B2
A hybrid electric vehicle includes an internal-combustion engine (ICE) and an electric machine coupled to a battery, an off-board power (OBP) system, and a controller, which are configured to power internal vehicle and battery charge electrical loads, and external electrical loads. The controller monitors the electrical loads, and responds to an OBP signal identifying an external electrical load, and commands the ICE and electric machine to generate a combined-power greater than or equal to the loads. This ensures that a battery state-of-charge is sustained and not depleted by power delivery to the external loads. The controller also generates a power-difference signal that identifies a difference between power generated by the electric machine and power consumed by the internal and external OFB electrical loads, such that the controller can adjusted the generated combined-power to minimize the power-difference signal and battery charge-discharge-cycles.
US10227063B2
A medical device for monitoring biological parameters through an Abreu Brain Thermal Tunnel (ABTT) is provided. By monitoring and analyzing the temperature of the ABTT, it is possible to diagnosis changes in a patient or subject under a variety of conditions, including predicting the course of medical conditions. Furthermore, since the ABTT is predictive, analysis of the ABTT may be used to control mechanisms for safety when an impending medical condition makes such operation hazardous.
US10227058B2
One aspect of the present invention is a vehicle state monitoring device including: a transmission unit configured to wirelessly transmit a state signal providing a notification of a vehicle state; a power generator fixed to the vehicle body, and comprising a vibration power generation element configured to perform vibration power generation by vibration from the vehicle body; and a controller configured to start up the transmission unit when power generated by the vibration power generation is supplied from the power generator, and configured to wirelessly transmit the state signal to the transmission unit.
US10227052B2
An elastic tubular body includes a grommet fitted to an opening edge of a mounting hole of a support body, a flared portion formed in a flare shape and deformable so as to invert an inner face and an outer face and having a large diameter edge coupled to the grommet; and a bellows-like tube of a bellows-like tubular shape having a smaller diameter than an inner diameter of a small diameter edge of the flared portion, a first end of the bellows-like tube connected with the small diameter edge of the flared portion. The flared portion is configured to be in a state projecting from the grommet or in a state where the outer face is reversed to enter inside the inner face and store the flared portion in a storage space of the grommet. The bellows-like tube is stored inside the flared portion stored in the storage space.
US10227044B2
A movement mechanism comprising a substantially spherical holder and a substantially bowl-shaped ring, which are rotatable relative to each other about a first axis and a second axis enclosing an angle of approximately 90° to the first axis. Driving means are provided for enabling movement of the holder relative to the ring and comprise a first non-straight driving rod bearing-mounted in the holder, as well as means for activating the driving rod and a second non-straight driving rod bearing-mounted in the holder, as well as means for activating the driving rod. The first driving rod and the second driving rod are rotatable about a third and a fourth axis, respectively, which third and fourth axes are mutually parallel and lie in a plane equal or parallel to the top face of the holder and which third and fourth axes are parallel to or coincide with the first axis.
US10227038B2
The invention relates to a regulation speed display apparatus of a vehicle. The apparatus causes a display device to display a detected regulation speed as a standard regulation speed when a traffic sign in a shot landscape is not a traffic sign with an auxiliary sign. The apparatus causes the display device to display the detected regulation speed as the standard regulation speed when the traffic sign in the shot landscape is the traffic sign with the auxiliary sign and the detected regulation speed is larger than an already displayed standard regulation speed. The apparatus causes the display device to maintain the display of the already displayed standard regulation speed when the traffic sign in the shot landscape is the traffic sign with the auxiliary sign and the detected regulation speed is equal to or smaller than the already displayed standard regulation speed.
US10227037B2
A lamp device for a vehicle includes a lamp housing and a light-emitting unit disposed therein. The light-emitting unit includes a light-emitting surface adjustable in at least one of a shape, an intensity of illumination, or a color of illumination. The lamp device further includes a bracket that supports the light-emitting unit to be mounted in the lamp housing, and that is configured to change the shape of the light-emitting surface of the light-emitting unit. The lamp device further includes a driving unit configured to apply a driving force to the bracket that changes the shape of the light-emitting surface of the light-emitting unit. The lamp device is configured to at least partially change, based on a plurality of lighting modes, at least one of the shape of the light-emitting surface, the intensity of illumination emitted from the light-emitting surface, or the color of illumination emitted from the light-emitting surface.
US10227026B2
A vehicle seat includes a frame member (13) of the seat, a cushion material (14) covering the frame member, a soft member (25) that is softer than the cushion material and secured to the frame member, and a weight (24) located in the soft member.
US10227024B2
A seat cover, comprising: a cover main body that is formed by stitching together a plurality of covering pieces at a plurality of seam allowances, and that covers a padding material of a vehicle seat, with a portion of the plurality of seam allowances disposed at a back face side of the cover main body facing the padding material being turned over to lie along a surface of the padding material; and a low friction cloth that is attached to the back face side of the cover main body in a state straddling across the portion of the plurality of seam allowances, and that is interposed between the cover main body and the padding material, with a surface of the low friction cloth that contacts the portion of the plurality of seam allowances having a lower coefficient of friction than a coefficient of friction of the surface of the padding material.
US10227002B2
A vehicle display system includes a display device, a driver state determiner, and a display controller. The display device is configured to provide a display on a window in a rear portion of a vehicle. The driver state determiner is configured to determine whether a driver of the vehicle checks a rear area of the vehicle. The display controller is configured to control displaying of the display device to change the display provided by the display device in accordance with a determination result of the driver state determiner.
US10226995B2
Provided is a working vehicle comprising: a fuel tank; a tank support member configured to receive and support the fuel tank from below; and an inverse U-shaped hood support member provided upright in a state of spanning left and right of the fuel tank, the hood support member including an elastic member that acts on an upper portion side of the fuel tank so as to hold the fuel tank at a predetermined position on the tank support member.
US10226993B2
An assembly (20) comprising a radial piston hydraulic motor (10), comprising a fixed housing (15), a shaft (14) that can be driven in rotation by the hydraulic motor (10), a wheel hub (30) comprising a hub barrel (31) that engages on the shaft (14), a bearing (40), a bearing support (41), in which the bearings (40) are housed between the hub barrel (31) and the bearing support (41) of the hydraulic motor (10), the bearing support (41) forming part of the housing (15), such that the bearing function is carried out by the housing (15), the shaft (14) supporting only the weight of same and having only a torque function.
US10226977B2
A vehicle suspension comprises an assembly of a hub carrier and a support arm, the support arm being attached to the hub carrier at two points spaced from each other in the direction of travel and extending inwardly therefrom to a support arm attachment point for fixing to a chassis, and a trailing link extending from the assembly in a direction transverse to that of the support arm, toward a trailing link attachment point for fixing to the chassis. The trailing link preferably extends from the assembly in a forward direction, and is preferably connected directly to the hub carrier. A strut can extend upwardly toward an attachment point for fixing to a chassis, to provide a spring and damper. The support arm can comprise a pair of arms extending divergently from the attachment point to each of the two points. A toe control link extends generally parallel to but spaced from the rear arm, linking the hub carrier to the chassis to provide geometry control under high load conditions. The invention further relates to a vehicle, comprising a chassis and at least two wheels, one on each side of the vehicle, each wheel being attached to the chassis via such a suspension.
US10226976B2
A ball hitch cover. The ball hitch cover includes a front tab and a pair of side tabs connected to a lower end of the front tab. Each side tab includes a first edge having a first width and a second edge having a second width, wherein the second edge width is greater than the first edge width. A pair of rear tabs are disposed opposing the front tab, such that each rear tab is disposed adjacent to the second edge of one of the side tabs of the pair of side tabs. A length of each rear tab of the pair of rear tabs is greater than a length of the front tab. The ball hitch cover is flexible and configured to conform to the shape of a ball hitch and is securable thereto via an adhesive disposed on an inner side of the ball hitch cover.
US10226972B2
A pressure medium supply device for a tire of a wheel unit, a wheel unit, and a valve arrangement for a rotationally fixed transition of a pressure medium supply device for a wheel unit are provided. The valve arrangement has a housing part through which a pressure medium can flow, a control piston, in particular an axially movable control piston which is received on the housing part, and a discharge element with an outlet for conducting the pressure medium. The housing part and the discharge element are received in a rotatable manner relative to each other. The control piston has a flow channel for the pressure medium, has a force application surface to which the pressure medium can be applied, and can be moved between a disengaged position and an engaged position. A pressure medium line can be established between the housing part and the discharge element in the engaged position.
US10226971B2
The air transmission structure includes a stator—having an annular outer wall with at least one aperture, an air inlet, and an air passage between the air inlet and the at least one aperture on the annular outer wall—biased against the non-rotating spindle. A housing includes interior annular walls mounted in radially spaced relation with the annular outer wall of the stator to form an annular cavity therebetween, and at least one aperture formed through the interior annular wall, and air outlet, and an air passage between the at least one aperture and air outlet. A seal is inserted within the annular cavity and defines a radial air passage between the apertures defined within the stator annular outer wall and the housing interior annular wall. An annular bearing between the stator and housing is configured to allow the housing to rotate with respect to the stator.
US10226966B2
The present invention provides: a pneumatic radial tire for a passenger car, the tire having cross sectional width SW and outer diameter OD satisfying a predetermined relationship formula when the tire is assembled with a rim and inflated at internal pressure of at least 250 kPa; a tire-rim assembly formed by assembling bead portions of said tire with the rim; and a method for using a tire, including preparing a pneumatic radial tire for a passenger car in which cross sectional width SW and outer diameter OD of the tire satisfy a predetermined relationship formula, and using the tire at internal pressure of at least 250 kPa.
US10226961B2
This soundproof wheel includes a soundproofing device (3) which is mounted to an inner peripheral surface (6) of a rim section (5) of the wheel. The soundproofing device (3) is provided with: a fixing ring (10) which is fitted in and fixed to a groove (8) formed in the inner peripheral surface (6); a first elastic body section (11A) which is stuck to an outer peripheral surface (10a) of the fixing ring (10), is disposed within the groove (8), and has a plurality of first elastic body pieces; an additional mass section (12) which is stuck to a side of the first elastic body section (11A) opposite to the fixing ring (10), is disposed within the groove (8), and has a plurality of additional mass pieces; and a second elastic body section (11B) which is stuck to a side of the additional mass section (12) opposite to the first elastic body section (11A), is disposed within the groove (8), and has a plurality of second elastic body pieces. The soundproofing device (3) includes a plurality of dynamic vibration absorbers. Each of the dynamic vibration absorbers has first and second elastic body pieces and an additional mass piece. This soundproof wheel allows for significant reduction in wheel vibration noise and is highly durable.
US10226960B2
A method for the refinement of a panel and an apparatus for the refinement of a panel according to a method of this type. The method for the refinement of a panel includes: unpacking of a panel having a core made from wood material from a transport-safe packaging, a grounding in the form of at least one synthetic resin layer pressed together with the core and, if appropriate, a primer being arranged on a top side of the core, and a coating being arranged on a core underside lying opposite the top side of the core, and connection and locking means being attached to at least two mutually opposite side faces; application of a decorative layer having a decoration to the grounding or primer; and application of at least one wear layer to the decorative layer.
US10226946B2
A post-processing device is provided with a post-processing unit which performs post-processing of a recording medium on which recording is performed, a transport path through which the recording medium is transported, or a deformation suppressing unit which suppresses deformation of the recording medium on a mounting unit on which the recording medium is mounted, in which the deformation suppressing unit is controlled based on a predetermined parameter related to recording processing with respect to the recording medium.
US10226943B2
A printing apparatus includes: a main body; a cassette including a cassette case and a printing medium accommodated in the cassette case; an installing portion provided on the main body for installing the cassette detachably; a thermal head arranged on a substrate provided in the installing portion and having heating elements arranged along a predetermined arrangement direction; a conveyor which conveys the printing medium of the cassette installed in the installing portion along a conveyance path orthogonal to the arrangement direction; a first temperature sensor provided, in the installing portion, on a side of the thermal head with respect to the conveyance path; a second temperature sensor provided in the interior of the cassette case or the installing portion; and a processor which corrects an amount of applying energy to be applied to the heating elements, based on first and second temperatures detected by the first and second temperature sensors.
US10226924B2
A printer for printing on a print medium as said print medium advances through a print zone, the printer including a number of print heads extending over the print zone, each print head including at least one nozzle array wherein at least two adjacent nozzle arrays overlap forming at least one stitching zone in the overlap region; and a printer controller for generating a sequence of nozzle firing commands for each nozzle array to selectively deposit droplets of print fluid on said print medium from said nozzle arrays in accordance with an image to be printed, wherein the printer controller further applies masks having decorrelated patterns to said sequence of firing commands for at least those overlapping nozzles of the nozzle arrays coinciding with the at least one stitching zone to obtain a predetermined optical parameter of the printed image in the stitching zone, irrespective of an offset between two adjacent nozzle arrays.
US10226922B2
An ink jet head includes a substrate having a pressure chamber formed therein, the pressure chamber being in communication with a nozzle through which ink is to be discharged, a first plate that is deformable to change a volume of the pressure chamber, and a second plate between the first plate and the pressure chamber, that stretches in response to an electric signal applied thereto. The second plate contracts in an in-plane direction to cause the first plate to deform and thereby the volume of the pressure chamber to be enlarged, when the electric signal is applied, and the second plate returns to an original shape thereof to cause the first plate to return to an original shape thereof and thereby the volume of the pressure chamber to return to an original volume thereof, when the electric signal is no longer applied.
US10226912B2
An interlayer film for laminated glass that can improve a sound insulation property of an obtained laminated glass when the interlayer film for laminated glass is used for configuring the laminated glass is provided. The interlayer film for laminated glass according to the present invention includes a first layer and a second layer laminated on a first surface of the first layer. The first layer includes a polyvinyl acetate resin and a plasticizer.
US10226899B2
A mandrel assembly is configured to receive one or more layers of composite material to form a component. The mandrel assembly may include a tower having an outer forming wall surrounding a central passage, and an upper ring removably secured to the tower. The upper ring is configured to be removed from the tower after the layer(s) of composite material are wrapped around the outer forming wall and at least a portion of the upper ring. The component is removed from the tower after the upper ring is removed from the tower.
US10226897B2
Apparatus and methods for impinging a heated fluid onto the surface of a substrate and then locally removing the impinged fluid. The apparatus and methods may be used to heat a surface of a substrate e.g. so that the substrate can be melt-bonded to another substrate.
US10226894B2
The invention relates to a method and a production line for making tangible products by layerwise manufacturing.The production line comprises (i) a first and a second building platform (102, 112) for carrying a tangible product, (ii) a deposition head (101) for providing a layer of construction material onto the building platforms, (iii) a conveyor (103) for conveying the building platforms in a conveying plane towards and away from the deposition head repeatedly, (iv) height adjustment means (107) to adjust the distance between the deposition head and the building platforms by displacing the building platforms relative to the conveyor in a direction (104) perpendicular to the conveying plane. The production line may further comprise a picking unit (106) for picking a product from the building platforms.The method allows making different tangible products in a continuous process by layerwise manufacturing. The method comprises a step of moving the platforms on which a product is made repeatedly past a material providing device for depositing subsequent layers and a step of adjusting the distance between such device and the building platforms by moving the platforms in a vertical direction.
US10226892B2
Method for manufacturing a continuous composite tube comprising translating a tube liner through a manufacturing station wherein the manufacturing station comprises a winding station and a consolidation station located at a distance downstream of the winding station; winding a composite tape on the tube liner at the winding station for forming a tape layer; consolidating the composite tape on the tube liner at a consolidation zone of the consolidation station by pressing and heating to the tape.
US10226878B2
A food slicing machine is provided for slicing food products such as bacon, cheese or cooked meat for sale as groups of slices in separate packs. The food slicing machine includes a cutter for cutting slices from the food product and a controller for controlling the thickness of the slices. The machine cuts slices according to a first value of a slicing parameter until the controller determines when the amount of food product remaining to be sliced in an end portion of the food product is less than a predetermined group weight threshold. The controller causes a slice to be cut according to a second, different value of the slicing parameter from the end portion for addition to an under-weight group of slices, so that its weight at least equals the predetermined group weight threshold.
US10226874B2
A handle for a razor cartridge is provided. The handle includes a head and the head has a cartridge engaging end configured to receive a razor cartridge, and an attachment end includes a stem, a pair of posts disposed on opposite sides of the stem, and at least one protrusion, the at least one protrusion being configured to interact with a handle body to facilitate attachment of the attachment end thereto. The stem defines a centerline and the protrusion extends away from the stem and the centerline. In an embodiment where the attachment end includes a pair of protrusions, one of the protrusions may be longer than the other protrusion.
US10226872B2
An electric shaving assembly for shaving decorative designs in hair includes a shaver. A cutting assembly is operationally coupled to the shaver and is configured to cut hair. Each of a plurality of masks is selectively couplable to the shaver to cover the cutting assembly. Each of a plurality of openings is positioned in a top of a respective mask. Each opening has a shape so that the plurality of openings has a variety of shapes, such as letters of the alphabet and designs. Each mask is configured to contact skin of a user to position the cutting assembly to shave a respective shape into the hair on the skin.
US10226868B2
The present disclosure provides a post position adjustment device, a cassette adjustment device and a substrate conveyance system. The post position adjustment device includes: a post-picking-and-placing unit configured to pick a post out from current positioning hole and install the post into a target positioning hole; a movement mechanism configured to move the post-picking-and-placing unit; and a movement control unit configured to control the movement mechanism to move the post-picking-and-placing unit to a source position where the post is currently located, and after the post has been picked out from the current positioning hole by the post-picking-and-placing unit, control the movement mechanism to move the post-picking-and-placing unit to a target position.
US10226867B2
A robot capable of substituting a plurality of parameter candidates in a point by a single-kind instruction sequence in accordance with the point is provided. A robot stores a main program, a sub program referred when the main program is executed, and a plurality of parameters. The sub program contains an instruction sequence containing a variable, and defines control details. The parameters are substitution candidates for the single kind of variable. The parameter to be substituted in the single kind of variable is determined, and one of the memory areas where the parameter is stored is interlinked with the variable in accordance with a determination result.
US10226863B2
The present invention is to provide an industrial robot, which is placed in vacuum for use, capable of efficiently cooling down hand- or arm-driving motors which are arranged inside the arm in air. The industrial robot is provided with a motor for rotating a second arm unit with respect to a first arm unit, a motor for rotating a hand with respect to the second arm unit, a reduction gear for reducing the rotation of the motor and transmitting it to the second arm unit, and a reduction gear for reducing the rotation of the motor and transmitting it to the hand; the hand and the arm are placed in vacuum. The reduction gears and are coaxially arranged so that the center of rotation of the second arm unit with respect to the first arm unit coincides with the axial centers of the reduction gears. The interior space of the hollow first arm unit is kept at atmospheric pressure in which the motors and the reduction gears are arranged.
US10226854B1
In an embodiment, a polycrystalline diamond compact (“PDC”) includes a substrate and a polycrystalline diamond (“PCD”) table bonded to the substrate. The PCD table includes an upper surface. The PCD table includes a first PCD region including bonded-together diamond grains and exhibits a first diamond density. At least a portion of the first PCD region extending inwardly from the working surface is substantially free of metal-solvent catalyst. The PCD table includes an intermediate second PCD region bonded to the substrate, which is disposed between the first PCD region and the substrate. The second PCD region includes bonded-together diamond grains defining interstitial regions, with at least a portion of the interstitial regions including metal-solvent catalyst disposed therein. The second PCD region exhibits a second diamond density that is greater than that of the first diamond density of the first PCD region.
US10226845B2
A machine tool capable of facilitating a process of mounting a fluid supplying unit to a spindle supporting unit is provided. The machine tool has a rotating unit including a spindle provided with a workpiece chucking unit, a supporting unit which rotatably supports the spindle around a spindle axis, and a fluid supplying unit removably mounted on a rear end of the supporting unit to allow fluid flow inside the spindle toward the chucking unit. The fluid supplying unit has an insert to be received in the rotating unit in the direction of the spindle axis. A labyrinth clearance is formed between the outer circumferential surface of the insert and the inner circumferential surface of the rotating unit when the fluid supplying unit is mounted on the rear end of the supporting unit. The labyrinth clearance allows rotation of the rotating unit and restricts leakage of the supplied fluid from inside the spindle when the rotating unit is rotated.
US10226832B2
A power supply for welding, cutting and similar operations includes a dual two-switch forward converter. The converter has two inverter circuits coupled in parallel but controlled to provide output power in an interleaved fashion. To avoid “walking” of the circuits (which could result in different duty cycles and imbalance of the load sharing), control signals are determined and applied to a first of the inverter circuits, and “on” times of the first circuit is monitored, such as by augmenting a counter to determine the number of clock cycles the first circuit is “on”. The same duration is then used for commanding output from the second inverter circuit. The duty cycles of both circuits is thus ensured to be the same regardless of changes in the total output power.
US10226825B2
A tool holding apparatus for interfacing a machine spindle receiver of a milling machine, which includes a holder nose connected to a holder body configured with a first divided section integrally connecting to a second divided section and a centralized axial bore for housing therewithin a tension bolt, a lock nut, and a thrust nut. The holder nose includes an axial bore incorporating a reverse-tapered configuration and three flat sectors to correspond with an equally configured shaft portion of a tool, whereupon the threaded attachment of the thrust nut to the holder nose furthers a locking arrangement of the tool within the axial bore to prevent inadvertent axial and rotational movement thereof during aggressive milling operations.
US10226818B2
A process for joining two or more powder injection molded parts by preparing at least two green parts from a feedstock including a binder and an injection powder. Placing the two or more green part into intimate contact, and maintaining the two green parts in intimate contact at a position with a linkage between the at least two green parts to produce an interconnected green assembly. Placing the assembly under shape retaining conditions, melting the binder of the interconnected green assembly under shape retaining conditions to produce a seamless body.
US10226816B2
A method and an assembly for production of a mechanical component by sintering a pulverulent material, the method including: providing a pulverulent metallic material including grains, the pulverulent metallic material having a determined melting temperature; agglomerating a given quantity of the pulverulent metallic material under pressure inside a cavity; providing thermal energy to the given quantity of pulverulent metallic material to bring it to a given temperature below the melting temperature; and shocking the given quantity of agglomerated pulverulent metallic material and brought to the given temperature to bind the grains of the pulverulent metallic material to each other to obtain one solid body. The one solid body is thus maintained under pressure and thermal energy accumulated in the solid body is made to dissipate to obtain the mechanical component.
US10226815B2
A core discharge device is provided for discharging a sand core from a cast material in which the sand core contains a binder having water glass. The core discharge device includes a humidified gas supply device that supplies humidified gas to the sand core inside the cast molded article. The humidified gas is a gas to which humidity has been added and from which droplets have been removed.
US10226814B2
A cast component includes a cast body that has a single crystal microstructure and an internal corner bounding an internal cavity. The single crystal microstructure defines a critical internal residual stress with respect to investment casting of the cast body using a refractory metal core beyond which the single crystal microstructure recrystallizes under a predetermined condition. The internal corner has a corner radius that is greater than a critical corner radius below which an amount of internal residual stress in the single crystal microstructure exceeds the critical internal residual stress. The internal cavity includes a cross section less than about 20 mils near the corner radius.
US10226813B2
Provided are a method of manufacturing an aluminum-zinc-based alloy sheet using twin-roll casting and an aluminum-zinc-based alloy sheet manufactured thereby. Specifically, a method of manufacturing an aluminum-zinc-based alloy sheet, including preparing a melt by melting elements corresponding to an aluminum alloy including 0.5 wt % to 10 wt % of zinc, inevitable impurities and aluminum as a balance (step 1); and twin-roll casting by introducing the melt prepared in step 1 between a pair of rotating cooling rolls (step 2), and an aluminum-zinc-based alloy sheet manufactured thereby are provided.The present invention may manufacture an aluminum-zinc-based alloy sheet, in which twin-roll casting is known to be difficult due to a wide solid-liquid coexistence region, by twin-roll casting by using cooling rolls having high thermal conductivity and controlling a reduction force by the rotational speed of the rolls.
US10226805B2
Provided is a cam type press capable of controlling deformation of a flange of a panel in the course of processing the flange, thus reducing deformation such as a crease, or the like, of the flange. The cam type press includes a padding cam installed to be movable in a slope direction. A slider is installed to be movable toward the padding cam, with a process gap into which a portion of a panel is inserted to form a flange between one side of the padding cam and one side of the slider. An adjustment block adjusts the process gap provided between the other side of the padding cam and the other side of the slider.
US10226790B2
A scanning laser having a wavelength compatible with a coating binder so as to cure it as the laser scans and irradiates the coating on a moving web. A system and method for curing flakes by providing a scanning laser which scans across a moving coated substrate in a magnetic field allows images to be formed as magnetically aligned flakes are cured into a fixed position. The images have regions of cured aligned flakes. The scanning laser cures the magnetically aligned flakes within it region it irradiates. Alternatively an array of lasers can be used wherein individual lasers can be switched on and off to fix irradiated coating as a moving web is moved at a high speed.
US10226789B2
A novel method of forming thin films of carbon nanotubes (CNTs) is described. In this method, carbon nanotubes are dispersed in a superacid solution and laid down on a substrate to form a conductive and transparent CNT network film. The superacid, in its deprotonated state, is an anion that has a permanent dipole moment. The superacid solution may be a pure superacid or have additional solvent. Preferably, the superacid solution does not contain an oxidizing agent. Novel, highly conductive and transparent CNT network films are also described.
US10226778B2
A lance for powder injection resulting in reduced agglomeration, including an outer tubular member having a first end, a second end, and an inner flowpath extending from the first end to the second end; an inner tubular member having a first end, a second end, and a, inner flowpath extending from the first end to the second end, the inner tubular member disposed within the inner flowpath of the outer tubular member for providing an annular space between the outer tubular member and the inner tubular member; and one or more orifices in the inner tubular member for providing a flowpath between the annular space and the inner flowpath of the inner tubular member. Additional lances, systems, and methods are also included.
US10226777B2
A showerhead bracket having a fluid inlet, a fluid outlet, a valve and a valve housing. The valve may be operably connected between the fluid inlet and the fluid outlet. The valve includes a valve inlet port, a low flow exit port and a high flow exit port. The valve housing is disposed between the fluid inlet and the valve inlet port. The valve can selectively rotate within the valve housing.
US10226774B2
A multi-zoned paddle screen apparatus 100 is disclosed for separating fiber from a liquid medium during, for example, a grain wet mill or dry grind process. The apparatus includes a housing 106 having first and second zones 108a, 108b situated adjacent one another along a length (L) of the housing 106. First and second screen sections 102a, 102b having a plurality of openings 104 may be situated lengthwise within the housing 106 corresponding with the first and second zones 108a, 108b, respectively. The first and second screen sections 102a, 102b have a circular cross-section, and the second screen section 102b has a larger diameter than the first screen section 102a. An elongated shaft 130 situated lengthwise within the screen sections 102a, 102b includes first and second conveyors 128a, 128b, which correspond with the first and second zones 108a, 108b, respectively, having a plurality of paddles 132. Each conveyor 128a, 128b is configured to move material in a direction along a length of the screen 102a, 102b. There may be more than two zones 108a, 108b.
US10226773B2
A micro heating device according to an embodiment of the inventive concept comprises a support part having at least one or more heating part, an oil chamber positioned over the support part and filled with oil therein, a specimen chamber having a reaction space into which a specimen is loaded and which is provided so as to be dipped into the oil, and a drive part configured to move the specimen chamber in the oil. The specimen chamber includes a temperature sensor for measuring a temperature of the specimen chamber.
US10226772B2
The invention relates to systems and methods including a combination of thermal generating device technologies to achieve more efficiency and accuracy in PCR temperature cycling of nucleic samples undergoing amplification.
US10226770B2
A thermal cycler for a microfluidic device includes a controller operable to provide a series of electrical signals, a heat sink, and a heating element in thermal communication with the heat sink and operable to receive the series of electrical signals from the controller. The thermal cycler also includes a thermal chuck in thermal communication with the heating element. The thermal chuck comprises a heating surface operable to make thermal contact with the microfluidic device. The heating surface is characterized by a temperature ramp rate between 2.5 degrees Celsius per second and 5.5 degrees Celsius per second and a temperature difference between a first portion of the heating surface supporting a first portion of the microfluidic device and a second portion of the heating surface supporting a second portion of the microfluidic device is less than 0.25° C.
US10226768B2
In certain embodiments this invention provides a pulsed-laser triggered microfluidic switching mechanism that can achieve a switching time of 70 μs. This switching speed is two orders of magnitude shorter than that of the fastest switching mechanism utilized in previous μFACS.
US10226764B2
A hydroprocessing catalyst composition that comprises a chelant treated metal containing support material having incorporated therein a polar additive. The catalyst composition is prepared by incorporating at least one metal component into a support material followed by treating the metal incorporated support with a chelating agent and thereafter incorporating a polar additive into the chelant treated composition.
US10226754B2
A lean NOx trap composition for the treatment of exhaust gas emissions, such as the oxidation of unburned hydrocarbons (HC), and carbon monoxide (CO), and the trapping and reduction of nitrogen oxides (NOx) is disclosed. The lean NOx trap composition can have a washcoat layer on a carrier substrate including a first support material comprising greater than 50% by weight of a reducible metal oxide; 10 to 30% by weight of alkaline earth metal supported on a second support material comprising a refractory metal oxide and 50% or less by weight of a reducible metal oxide and; and a platinum group metal component supported on at least one of the first support material and/or the second support material. A portion of the first support material may further include 0.5% to 10% by weight of an alkaline earth metal.
US10226753B2
The invention relates to a process for producing superabsorbents, comprising the preparation of partly neutralized acrylic acid by the steps (i) preparing an over-neutralized acrylic acid having a degree of neutralization of at least 100.1 mol-% by mixing of an acrylic acid 1 and a base and (ii) preparing a neutralized acrylic acid having a degree of neutralization from 50 to 85 mol-% by mixing of the over-neutralized acrylic acid and an acrylic acid 2, wherein the content of dimeric acrylic acid in the acrylic acid 2 is lower than the content of dimeric acrylic acid in the acrylic acid 1.
US10226751B2
Provided are a core material for a vacuum insulation panel including porous aluminosilicate, and a vacuum insulation panel provided with the same. The core material for the vacuum insulation panel according to the present disclosure has superior long-term durability and improved gas adsorption ability (particularly, superior water absorption ability) while requiring a low raw material cost. The vacuum insulation panel including the core material may exhibit more improved insulation performance by minimizing a reduction in the vacuum degree without an additional getter or absorbent.
US10226749B2
A fluid catalytic cracking (FCC) unit for the production of hydrocarbon products includes a fluid injection system coupled to a reactor by a standpipe. The fluid injection system includes a plurality of nozzles for injecting oil feedstock into the standpipe to react with a catalyst flowing therethrough.
US10226746B2
The present technology relates to a gas transfer system having removable nozzle assemblies, ejectors or other gas transfer device(s). The nozzle assemblies are removably connected to a monolithic liquid/gas manifold. The present technology also provides nozzle assemblies having an inner nozzle, an outer nozzle adapted for connection to the inner nozzle, and a pipe adapter for connecting the inner nozzle to a liquid manifold.
US10226744B2
The present disclosure provides methods, compositions, kits and apparatuses for stabilizing membranes, membrane proteins, and/or membranes containing membrane proteins using hydrophobin.
US10226737B2
In one aspect, catalyst modules and catalytic reactors are provided which, in some embodiments, mitigate inefficiencies and/or problems associated with fluid stream pressure drop A catalyst module comprises a layer of structural catalyst bodies arranged in a pleated format, the structural catalyst bodies forming pleat inlet faces and pleat outlet faces, wherein fluid flow channels defined by inner partition walls of the structural catalyst bodies extend from the pleat inlet faces to the pleat outlet faces. The pleat inlet faces form an angle (δ) with an inlet face of the module.
US10226731B2
A method and system for collecting xenon (Xe) is described. A microchannel heat exchanger is used in combination with a mechanical cooler and an absorbent. A combination of components makes up a Xe Collection Subsystem that is adapted for use in an efficient process for collecting, purifying, and measuring Xe isotopes collected from air as part of the International Monitoring System.
US10226727B2
A filter assembly may include a housing and a cover movably connected to the housing and movable between an open position and a closed position. The filter assembly may also include at least one projection extending from the cover towards an interior of the housing and a filter element that fits at least partially within the housing. When the cover is moved from the open position to the closed position, at least one projection interfaces with the filter element and causes the filter element to pivot within the housing, such that the at least one projection seals the filter element and the housing together when the cover is in the closed position.
US10226720B2
An apparatus and a method is described to facilitate separation of hydrocarbons from solid particles (29) being contaminated with hydrocarbons. The apparatus (1) includes a container (3) having a closeable inlet portion (20) for solid particles; a support body (11) in fluid communication with the closeable inlet portion (20), where the support body (11) is arranged to carry the solid particles (29) led in through the inlet portion (20), as the container is connected to an under-pressure generating device (7) to provide an under-pressure in the container (3).
US10226715B2
A display panel system is provided and includes a plurality of planar polygonal display panels, each display panel removably connectible along at least one edge to an edge of an adjacent display panel with connectible zipper assemblies. Each display panel system may be composed of uniform material or of various materials. The display panel system may be draped as desired by use of suspension mechanisms and rigging lines.
US10226710B2
A virtual-reality navigation controller includes a base, a seat, a vertical support to support the seat on the base, and a rotatable connector between the seat and the vertical support to tilt the seat about a rotational center of the rotatable connector in response to directional forces exerted by a user seated on the seat. The virtual-reality navigation controller further includes a motion-detection controller to measure pitch corresponding to the tilt of the seat resulting from the directional forces.
US10226708B2
The disclosure provides a video playback system for use within a game application and/or other interactive computing environments. The video playback system can be used to capture gameplay during execution of a game application. The captured gameplay video can be processed and stored within the game application or in a network accessible location.
US10226695B2
Methods and systems are provided for independent audio volume control. For example, an audio component (e.g., implemented in an element of an audio setup) may control generation and/or outputting of a combined-game-and-chat audio signals. The audio component may receive user input comprising one or both of: a setting for a desired volume of a chat audio component of the combined-game-and-chat audio signal, and a setting for a desired volume of a game audio component of the combined-game-and-chat audio signal. The audio component may determine, based on the user input, a corresponding mix setting for mixing together of the chat audio component and the game audio component in an audio source to generate the combined-game-and-chat audio signal and a corresponding volume setting applicable at an audio output element; provide the mix setting to the audio source; and provide the volume setting to the audio output element.
US10226689B2
A game and a method of playing the game are disclosed. The game comprises a board having a domain region and a plurality of theme regions. Each theme region is associated with a theme. The game also provides each player with a plurality of game pieces, and each game piece of the plurality of game pieces is associated with an identifier. Each information bearing member of a plurality of information bearing members is associated with a theme and an identifier. Placing one game piece of the plurality of game pieces in one of the theme regions causes one of the plurality of information bearing members to be selected in accordance with the identifier associated with the placed game pieces and the theme associated with theme region in which such game piece was placed. Information specified by the selected information bearing member is presented to all of the players.
US10226688B1
A weighted chess piece, comprising a base having a first cavity and a second cavity therein, wherein the first cavity is filled with loose particles of metal and the second cavity contains an electronic sensor.
US10226683B2
A wheeled board device with forward and rearward in-line wheel structures attached to a user platform. The forward wheel may have a forward tilt axle or be otherwise direction-biased to permit lean-based turning. The rear wheel may be singular or comprise two tires or the like and be motorized or not. The wheels are preferably large to more readily handle surface irregularities. A self-balancing wheelie mode is disclosed in one embodiment. Other embodiments include placement of the forward tilt axle within or without the envelope of the front wheel. The user platform is below the top of the rear wheel and preferably near the axis of the rear wheel, among other features.
US10226671B2
A golf club head includes a club body including a crown, a sole, a skirt disposed between and connecting the crown and the sole and a face portion connected to a front end of the club body. The face portion includes a geometric center defining the origin of a coordinate system when the golf club head is ideally positioned, the coordinate system including an x-axis being tangent to the face portion at the origin and parallel to a ground plane, a y-axis intersecting the origin being parallel to the ground plane and orthogonal to the x-axis, and a z-axis intersecting the origin being orthogonal to both the x-axis and the y-axis. The golf club head defines a center of gravity CG, the CG being a distance CGY from the origin as measured along the y-axis and a distance CGZ from the origin as measured along the z-axis.
US10226662B1
A multipurpose exercise device including a frame and a panel. The frame includes a plurality of legs, and a support assembly that secures the legs in a vertical position, or allows the legs to freely rotate to allow the frame to fold flat. The support assembly includes an adjustment mechanism to adjust a distance between the legs. A panel is detachably securable to the frame in a flat or inclined position.
US10226660B2
A weight stand assembly for use in assisting a user prior to performing an exercise movement or repetition by way of holding exercise weights used by the user in a relatively stable and proper starting position for the user. More particularly, the weight stand assembly is retractable in that it pivotally falls in a relatively backwards direction away from the user and towards a ground surface after the exercise weights have been lifted by the user, thereby preventing injury and thus enhancing performance of the user by allowing the user to complete a full set of exercise repetitions without being inhibited by a placement and location of the weight stand assembly.
US10226658B2
An apparatus for physical exercise comprising a resistance arrangement having at least one hydraulic cylinder adapted for providing resistance forces in at least a first and a second direction, the apparatus having a force transmission assembly through which the resistance forces are operable. The force transmission assembly having at least one actuation member being in operable engagement therewith and being adapted to transfer forces generated by a user in at least two directions of motion to the at least one hydraulic cylinder via the force transmission assembly. The resistance forces created by the at least one hydraulic cylinder opposing the user generated forces.
US10226651B2
A test cell for an aircraft turbojet, wherein the test cell comprises a U-shaped configuration, with a passageway in the form of an elongated corridor, an inlet chimney, and an outlet chimney. The corridor includes a securing area with a securing arm for holding the turbojet during its test. The passageway furthermore reveals an upstream shutter and a downstream shutter, the two shutters including one pivoting flap or a series of pivoting flaps. In the event of a fire, the shutters close due to autonomous return means. Gravity allows the flap(s) to come down to the closed position and to confine the turbojet in order to rapidly stifle the fire.
US10226642B2
Systems and methods for restructure and stabilization of bones that provide an anti-microbial effect are disclosed herein. A device includes a delivery catheter having an inner void for passing at least one light sensitive liquid, and an inner lumen; an expandable member releasably engaging the distal end of the delivery catheter; at least one channel positioned in the expandable member; and a light conducting fiber sized to pass through the inner lumen of the delivery catheter and into the expandable member, wherein, when the light conducting fiber is in the at least one channel, the light conducting fiber is able to disperse light energy to provide an anti-microbial effect. When the light conducting fiber is in the expandable member, the light conducting fiber is able to disperse the light energy to initiate hardening of the light sensitive liquid within the expandable member to form a photodynamic implant.
US10226639B2
A method and medical device for detecting a cardiac event that includes sensing cardiac signals from a plurality of electrodes, the plurality of electrodes forming a first sensing vector sensing a first interval and a second sensing vector simultaneously sensing a second, determining, for each of the first interval and the second interval, whether each beat of the plurality of beats is one of a match beat and a non-match beat, determining whether each beat of the plurality of beats is one of a high confidence beat and a low confidence beat, determining, for each of the first interval and the second interval, the number of beats determined to be both a non-match beat and a high confidence beat is greater than a non-match threshold, and determining whether to deliver therapy for the cardiac event in response to identifying of each of the first interval and the second interval as being one of shockable and not shockable.
US10226636B2
Devices, systems, and techniques for estimating energy transfer to tissue of a patient during battery charging for an implantable medical device are disclosed. Implantable medical devices may include a rechargeable power source that can be transcutaneously charged. An external charging device may calculate an estimated energy transfer to tissue of the patient that may include a resistive heat loss from the rechargeable power source and/or electromagnetic energy transfer directly to tissue. Based on the estimated energy transfer, the external charging device may select a power level for charging of the rechargeable power source. In one example, the charging device may select a high power level when the estimated energy transfer has not exceeded an energy transfer threshold and select a low power level when the estimated energy transfer has exceeded the energy transfer threshold.
US10226629B2
Embodiments are directed to a computer implemented neural stimulation system having a first module configured to derive neural data from muscle contractions or movements of a subject. The system further includes a second module configured to derive a neural state assessment of the subject based at least in part on the neural data. The system further includes a third module configured to derive at least one neural stimulation parameter based at least in part on the neural state assessment. The system further includes a fourth module configured to deliver neural stimulations to the subject based at least in part on the at least one neural stimulation parameter.
US10226626B2
Selective high-frequency spinal cord modulation for inhibiting pain with reduced side effects and associated systems and methods are disclosed. In particular embodiments, a programmer has instructions that, in response to an input, select between a paresthesia-inducing therapy program that includes a frequency of less than 1,500 Hz, and a non-paresthesia-inducing therapy program that includes a frequency in range from 1.5 kHz to 50 kHz.
US10226603B1
Methods and devices are disclosed for passing Chronic Total Occlusion (CTO) from subintimal location and re-entry into a true-lumen of the patient using transient fenestration approach. The transient fenestration is induced by balloon dilatation within the CTO, and a guidewire quickly trails into a true lumen.
US10226599B2
An inflatable balloon is provided. The balloon includes a central lumen open at both ends of the balloon and connected to a gap formed in one sidewall of the balloon. This arrangement may provide the balloon with a generally C-shaped profile with the open central lumen within the balloon along a center axis thereof, such as to allow for perfusion. The balloon may also include an inflation port offset from a central axis and a shaft including an inflation lumen connected to the inflation port. A sheath may also be provided with a window through which the balloon may project in use.
US10226598B2
An interventional catheter is adapted for treating a blood vessel. In an embodiment, the catheter includes an elongate shaft sized for insertion in a blood vessel and a stent positioned on a distal region of the elongate shaft. An expandable dilation member is coupled to a distal region of the elongate shaft. The expandable dilation member is adapted to expand outward. A stent containment member is positioned over the elongate shaft and the stent to contain the stent in a collapsed state.
US10226591B1
The present invention pertains to a system, method, and device for treating sleep disorders. The present invention is particularly useful in the delivery of carbon dioxide (CO2) to a subject and in the treatment of sleep apnea. Furthermore, integration of components with various sensors and apparatuses associated therewith and attached thereto preferably complete a rebreathing circuit in the present invention. In various embodiments of the present invention where the above components are integrated as a rebreathing circuit, a subject is both the source and recipient of a controlled concentration of carbon dioxide. In such embodiments, treatment of sleep disorders becomes much more efficient and effective.
US10226590B2
A pressure support device implements compensation for variations in air density of its operating environment. A pressurized flow of breathable gas is generated for delivery to the airway of a subject. One or more parameters associated with the ambient environment of the pressure support device are determined. These parameters can include one or more of an ambient barometric air pressure, an ambient air temperature, or ambient air humidity. In some embodiments, one or more assumed parameters associated with the ambient environment of the pressure support device are determined based on typical sleeping conditions of the subject. An ambient air density of the ambient environment of the pressure support device is estimated based on one or more of the parameters and/or assumed parameters. A flow rate of the pressurized flow of breathable gas is adjusted based on the estimated ambient air density of the ambient environment of the pressure support device.
US10226576B2
Sensors are attached to a living being so as to generate corresponding sensor signals. A monitor is in communications with the sensors so as to derive physiological parameters responsive to the sensor signals. Predetermined limits are applied to the physiological parameters. At least one indicator responsive to the physiological parameters and the predetermined limits signal the onset of a sepsis condition in the living being.
US10226556B2
An apparatus for extracting at least one blood component contained in a primary bag of a system of bags, said system of bags comprising at least one bag of solution containing an additive solution for said blood component and at least one collecting satellite bag configured to collect said blood component to which said additive solution has been added, said bags being connected to one another by tubes, said apparatus comprising an extraction device configured to extract the blood component by compressing the primary bag, and a control device configured to transfer said extracted component or of said extracted component and of the additive solution, to the collecting satellite bag by the intermediary of tubes, further comprising: an agitation device, and a drive system, said system being designed to enable the uniform mixing of the extracted blood component and of the additive solution in said collecting satellite bag.
US10226555B2
An illumination element such as an optical waveguide for illuminating a surgical field in a patient has a light input section, a light transmitting section, and a light output section. The light input section is optically coupled to a proximal section of the light transmitting section and inputs light into the illumination element. The light transmitting section transmits the light preferably by total internal reflection or by other transmission means. The light output section is adjacent a distal section of the light transmitting section which has a light extraction area from which the light exits with an energy density. The light extraction area is large enough to maintain the energy density at a level that prevents melting of the illumination element or burning of the patient, and the light extraction area has a profile that does not interfere with access to the surgical field.
US10226550B2
This disclosure relates to dermal treatment compositions, such as dermal fillers and tissue glues, and injectable compositions that incorporate one or more cationic steroidal antimicrobials (CSAs). The CSAs are incorporated into the dermal treatment compositions to provide effective antimicrobial, anti-inflammatory, analgesic, anti-swelling and/or tissue-healing properties. A treatment composition includes a component formed from a biologically compatible material suitable for injection into and/or application onto tissue at a treatment site. One or more CSA compounds are mixed with the biologically compatible material so that the one or more CSA compounds are incorporated within the composition, forming a reservoir of CSA compounds within the resulting bolus of the treatment composition after injection and/or application.
US10226549B2
There is provided a thermosensitive biodegradable hydrogel including MPEG-PCL to which a cell-adhesive peptide binds, and MPEG-PCL. The thermosensitive biodegradable hydrogel has excellent cellular adhesiveness while maintaining thermosensitivity of polymers intact, and is biodegradable in vivo after a predetermined period of time.
US10226534B2
The invention provides semi-solid systems for delivering biologically active materials that include a polymer comprising 1) one or more polycaprolactone (PCL) units and 2) at least one or more polyethylene glycol (PEG) units; wherein at least one of said polycaprolactone units is conjugated to a PEG forming an acetal group.
US10226533B2
Polymers are described herein comprising: a reaction product of a prepolymer solution including at least one macromer and at least one visualization agent; and an active agent electrostatically bound to the polymer filament or chemically bound to the at least one monomer; wherein the polymer filament does not include metallic support members.
US10226529B2
An object of the present invention is to provide an adjuvant for a mucosal vaccine with high safety that induces a sufficient immune response in a mucosal membrane. According to the present invention, an adjuvant for a mucosal vaccine containing a protein complex composed of hemagglutinin (HA) subcomponents HA1 and HA2, and mutant subcomponent HA3 of botulinum toxin is provided.
US10226525B2
The invention relates to immunogenic polysaccharide-protein conjugates comprising a capsular polysaccharide (CP) from Streptococcus agalactiae, commonly referred to as group B streptococcus (GBS), and a carrier protein, wherein the CP is selected from the group consisting of serotypes Ia, Ib, II, III, IV, V, VI, VII, VIII, and IX, and wherein the CP has a sialic acid level of greater than about 60%. The invention also relates to methods of making the conjugates and immunogenic compositions comprising the conjugates. The invention also relates to immunogenic compositions comprising polysaccharide-protein conjugates, wherein the conjugates comprise a CP from GBS serotype IV and at least one additional serotype. The invention further relates to methods for inducing an immune response in subjects against GBS and/or for reducing or preventing invasive GBS disease in subjects using the compositions disclosed herein. The resulting antibodies can be used to treat or prevent GBS infection via passive immunotherapy.