- Patent Title: Anti-HIV dual specificity antibodies and methods of HIV treatment
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Application No.: US14907360Application Date: 2014-07-23
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Publication No.: US09988438B2Publication Date: 2018-06-05
- Inventor: Seth Pincus , Ryan Craig
- Applicant: Board of Supervisors of Louisiana State University and Agricultural and Mechanical College
- Applicant Address: US LA Baton Rouge
- Assignee: Board of Supervisor of Louisiana State University and Agricultural and Mechanical College
- Current Assignee: Board of Supervisor of Louisiana State University and Agricultural and Mechanical College
- Current Assignee Address: US LA Baton Rouge
- Agency: Thomas | Horstemeyer, LLP
- International Application: PCT/US2014/047787 WO 20140723
- International Announcement: WO2015/013390 WO 20150129
- Main IPC: A61K39/21
- IPC: A61K39/21 ; C07K16/10 ; C07K16/46 ; A61K38/17 ; A61K39/00
Abstract:
Dual variable domain immunoglobulins (DVD Igs) are provided capable of tetravalent binding to bispecific sites of the human immunodeficiency virus (HIV). The DVD Igs may be asymmetric and may have more variable domains on either the light chain or the heavy chain of the Igs. The DVD Igs may have specificity for gp41 and gp120. Therapies are provided using DVD Igs to neutralize HIV viral loads.
Public/Granted literature
- US20160280771A1 ANTI-HIV DUAL SPECIFICITY ANTIBODIES AND METHODS OF HIV TREATMENT Public/Granted day:2016-09-29
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