Invention Grant
- Patent Title: Indolinone compounds and uses thereof
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Application No.: US15357876Application Date: 2016-11-21
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Publication No.: US09987251B2Publication Date: 2018-06-05
- Inventor: Jean-Michel Vernier
- Applicant: Oncternal Therapeutics, Inc.
- Applicant Address: US CA San Diego
- Assignee: Oncternal Therapeutics, Inc.
- Current Assignee: Oncternal Therapeutics, Inc.
- Current Assignee Address: US CA San Diego
- Agency: Knobbe, Martens, Olson & Bear, LLP
- Main IPC: C07D209/38
- IPC: C07D209/38 ; C07D403/10 ; A61K31/404 ; C07D401/06 ; C07D401/10 ; C07D209/34 ; A61K31/4155 ; A61K31/4439 ; A61K31/5377
Abstract:
Indolinone derivative compounds that act as EWS-FLI1 transcription factor inhibitors are provided. Also provided are pharmaceutical compositions of the indolinone derivatives, methods of synthesizing the same, methods of treating using same, and assays for identifying the inhibitors of EWS-FLI1 oncoprotein.
Public/Granted literature
- US20170066720A1 INDOLINONE COMPOUNDS AND USES THEREOF Public/Granted day:2017-03-09
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