The present disclosure provides a display substrate, a driving method thereof and a display device. The display substrate includes a touch region. Multiple touch electrodes are arranged in columns at the touch region, and the touch electrodes in each column are connected together. At a touch detection stage, the 5 touch electrodes in each column at the touch region are disconnected from the touch electrodes in the other columns, and at a display stage, the touch electrodes in the columns at the touch region are connected together and serve as common electrodes.