Invention Grant
- Patent Title: Antibody neutralizing human respiratory syncytial virus
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Application No.: US15335560Application Date: 2016-10-27
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Publication No.: US09963500B2Publication Date: 2018-05-08
- Inventor: Kalpit A. Vora , Kara S. Cox , Aimin Tang , Zhifeng Chen , Daniel DiStefano , Lan Zhang , Hua-Poo Su
- Applicant: Merck Sharp & Dohme Corp.
- Applicant Address: US NJ Rahway
- Assignee: Merck Sharp & Dohme Corp.
- Current Assignee: Merck Sharp & Dohme Corp.
- Current Assignee Address: US NJ Rahway
- Agent John David Reilly; Gloria Fuentes
- Main IPC: A61K39/395
- IPC: A61K39/395 ; A61K39/00 ; C07K16/00 ; C07K16/28 ; C12P21/06 ; C07K16/10 ; A61K39/42

Abstract:
The present invention relates to monoclonal antibodies which have high anti-RSV neutralizing titers. The invention further provides for isolated nucleic acids encoding the antibodies of the invention and host cells transformed therewith. The invention yet further provides for diagnostic, prophylactic and therapeutic methods employing the antibodies and nucleic acids of the invention, particularly as a passive immunotherapy agent in infants and the elderly.
Public/Granted literature
- US20170121394A1 ANTIBODY NEUTRALIZING HUMAN RESPIRATORY SYNCYTIAL VIRUS Public/Granted day:2017-05-04
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