Invention Grant
- Patent Title: High molecular weight, post-translationally modified protein brushes
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Application No.: US15155933Application Date: 2016-05-16
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Publication No.: US09963492B2Publication Date: 2018-05-08
- Inventor: Brian M. Seifried , Bradley D. Olsen
- Applicant: Brian M. Seifried , Bradley D. Olsen
- Applicant Address: US MA Cambridge
- Assignee: Massachusetts Institute of Technology
- Current Assignee: Massachusetts Institute of Technology
- Current Assignee Address: US MA Cambridge
- Agency: Foley Hoag LLP
- Agent Dana M. Gordon
- Main IPC: A61K38/00
- IPC: A61K38/00 ; C07K14/47 ; C07K1/107 ; C07K1/113
Abstract:
Disclosed are protein brushes that mimic mucin in physical and functional characteristics. The protein brushes have a variable number of tandem repeats similar to natural mucin and are modified at a number of their tyrosine residues to introduce brush substituents that mimic the hydrogel nature of mucin.
Public/Granted literature
- US20170029478A1 High Molecular Weight, Post-Translationally Modified Protein Brushes Public/Granted day:2017-02-02
Information query
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