In an example, there is provided a system and method for execution profiling detection of malicious software objects. An execution profiling (EXP) engine may be provided in conjunction with a binary translation engine (BTE). Both may operate within a trusted execution environment (TEE). Because many malware objects make assumptions about memory usage of host applications, they may cause exceptions when those assumptions prove untrue. The EXP engine may proactively detect such exceptions via the BTE when the BTE performs its translation function. Thus, malicious behavior may be detected before a binary runs on a system, and remedial measures may be provided.