Invention Grant
- Patent Title: Site-specific integration of transgenes into human cells
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Application No.: US14539909Application Date: 2014-11-12
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Publication No.: US09932607B2Publication Date: 2018-04-03
- Inventor: Michele Pamela Calos , Ruby Yanru Tsai , Fangfang Zhu , Matthew Gamboa , Alfonso P. Farruggio , Simon Hippenmeyer , Bosiljka Tasic , Birgitt Schüle
- Applicant: The Board of Trustees of the Leland Stanford Junior University
- Applicant Address: US CA Stanford
- Assignee: The Board of Trustees of the Leland Stanford Junior University
- Current Assignee: The Board of Trustees of the Leland Stanford Junior University
- Current Assignee Address: US CA Stanford
- Agency: Bozicevic, Field & Francis LLP
- Agent Edward J. Baba; Shweta Chandra
- Main IPC: C12N15/90
- IPC: C12N15/90
Abstract:
Methods for inserting a polynucleotide sequence into the genome of a human cell are provided. The present methods result in insertion of a polynucleotide sequence of interest into the H11 locus in the genome of a human cell. Also provided are nucleic acids that include sequences for integrating a polynucleotide sequence of interest into the H11 locus in the genome of a human cell. A transgenic human cell including site specific recombination sites at the H11 locus is also disclosed.
Public/Granted literature
- US20150140665A1 Site-Specific Integration of Transgenes into Human Cells Public/Granted day:2015-05-21
Information query
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