Invention Grant
- Patent Title: Proteins with repetitive bacterial-IG-like (Big) domains present in Leptospira species
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Application No.: US15334128Application Date: 2016-10-25
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Publication No.: US09932391B2Publication Date: 2018-04-03
- Inventor: Albert I. Ko , Mitermayer Galvão Reis , Julio Henrique Rosa Croda , Isadora Cristina Siqueira , David A. Haake , James Matsunaga , Lee W. Riley , Michele Barocchi , Tracy Ann Young
- Applicant: The United States of America represented by the Department of Veterans Affairs , The Regents of the University of California , Cornell Research Foundation, Inc. , Fundação Oswaldo Cruz—FIOCRUZ
- Applicant Address: US NY Ithaca US CA Oakland US DC Washington BR Rio de Janeiro
- Assignee: Cornell Research Foundation, Inc.,The Regents of the University of California,The United States of America represented by the Department of Veterans Affairs,Fundaçäo Oswaldo Cruz—FIOCRUZ
- Current Assignee: Cornell Research Foundation, Inc.,The Regents of the University of California,The United States of America represented by the Department of Veterans Affairs,Fundaçäo Oswaldo Cruz—FIOCRUZ
- Current Assignee Address: US NY Ithaca US CA Oakland US DC Washington BR Rio de Janeiro
- Agency: Klarquist Sparkman, LLP
- Main IPC: G01N33/53
- IPC: G01N33/53 ; C07K16/12 ; C12Q1/68 ; C07H21/04 ; C07K14/20 ; G01N33/569 ; A61K39/00
Abstract:
The invention relates to three isolated DNA molecules that encode for proteins, BigL1, BigL2 and BigL3, in the Leptospira sp bacterium which have repetitive Bacterial-Ig-like (Big) domains and their use in diagnostic, therapeutic and vaccine applications. According to the present invention, the isolated molecules encoding for BigL1, BigL2 and BigL3 proteins are used for the diagnosis and prevention of infection with Leptospira species that are capable of producing disease in humans and other mammals, including those of veterinary importance.
Public/Granted literature
- US20170037114A1 PROTEINS WITH REPETITIVE BACTERIAL-IG-LIKE (BIG) DOMAINS PRESENT IN LEPTOSPIRA SPECIES Public/Granted day:2017-02-09
Information query
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