Systems and methods for enhancing aircraft performance are provided. In one example, a method can include accessing an initial model that defines operating cost of an aircraft at a series of model operating states. The method also can include identifying one or more sample operating states for analyzing aircraft cost during flight. The method also can include receiving one or more real-time flight performance parameters indicative of aircraft operating cost while the aircraft is operating at the identified sample operating states. The method also can include generating an updated model that defines operating cost of the aircraft using the initial model as well as data defined by the real-time flight performance parameters. The method also can include determining an enhanced operating state based at least in part on the updated model and outputting the enhanced operating state for control of the aircraft.