A multi-part air data probe sensor assembly facilitating rapid replacement is provided. One example air data probe sensor assembly comprises a mount plate interface including at least one mount plate electrical connector configured to mate with electrical lines of an aircraft and at least one mount plate pneumatic connector configured to mate with pneumatic tubes of an aircraft; and a detachable sensor body having at least one sensor electrical connector that is coupled with the at least one mount plate electrical connector and at least one sensor pneumatic connector that is coupled with the at least one mount plate pneumatic connector; and a mechanical seal provided between the mount plate interface and the detachable sensor body, wherein the mechanical seal is composed of a moisture blocking material.