Invention Grant
- Patent Title: Cytochrome P450 and cytochrome P450 reductase polypeptides, encoding nucleic acid molecules and uses thereof
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Application No.: US14440122Application Date: 2013-10-31
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Publication No.: US09885023B2Publication Date: 2018-02-06
- Inventor: Carl Joerg Bohlmann , Maria Luisa Diaz Chavez , Jessie Moniodis
- Applicant: THE UNIVERSITY OF BRITISH COLUMBIA , THE UNIVERSITY OF WESTERN AUSTRALIA
- Applicant Address: CA Vancouver AU Nedlands
- Assignee: University of British Columbia,The University of Western Australia
- Current Assignee: University of British Columbia,The University of Western Australia
- Current Assignee Address: CA Vancouver AU Nedlands
- Agency: McDonnell Boehnen Hulbert & Berghoff LLP
- International Application: PCT/CA2013/050828 WO 20131031
- International Announcement: WO2014/067007 WO 20140508
- Main IPC: C12N15/53
- IPC: C12N15/53 ; C12N9/02 ; C12P5/00 ; C11B9/00 ; C12P7/02 ; C12P15/00

Abstract:
Provided are cytochrome P450 polypeptides, including cytochrome P450 santalene oxidase polypeptides, cytochrome P450 bergamotene oxidase polypeptides and cytochrome P450 reductase polypeptides. Also provided are nucleic acid molecules encoding the cytochrome P450 polypeptides. Cells containing the nucleic acids and/or the polypeptides are provided as are methods for producing terpenes, such as santalols and bergamotols, by culturing the cells.
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