- Patent Title: Crystal form of Dabrafenib mesylate and preparation method thereof
-
Application No.: US15247086Application Date: 2016-08-25
-
Publication No.: US09884856B2Publication Date: 2018-02-06
- Inventor: Haiping Lao , Xiaoxia Sheng , Xiaohong Sheng
- Applicant: Hangzhou Pushai Pharmaceutical Technology Co., LTD.
- Applicant Address: CN Hangzhou
- Assignee: HANGZHOU PUSHAI PHARMACEUTICAL TECHNOLOGY CO., LTD.
- Current Assignee: HANGZHOU PUSHAI PHARMACEUTICAL TECHNOLOGY CO., LTD.
- Current Assignee Address: CN Hangzhou
- Agency: Sterne, Kessler, Goldstein & Fox PLLC
- Priority: CN201310283705 20130708
- Main IPC: C07D239/02
- IPC: C07D239/02 ; C07D277/04 ; A61K31/505 ; A61K31/425 ; C07D417/04
Abstract:
The present invention involves novel crystal forms of Dabrafenib mesylate and preparation method thereof, wherein the novel crystal forms are more stable in water or an aqueous system, and have greater solubility and dissolution rate in water, thus having better stability and bioavailability compared with the existing crystal forms.
Public/Granted literature
- US20160368909A1 Novel Crystal Form of Dabrafenib Mesylate and Preparation Method Thereof Public/Granted day:2016-12-22
Information query
