The present invention provides apparatus for assisting change-over of take-up rolls in a printing system, especially in a roll-to-roll printing system. The apparatus comprises a guide device for directing or guiding printed sheet output from the printing system along a transport path towards a take-up roll for winding or taking up a length of the printed sheet, and a first clamping device for holding a new leading edge region of the printed sheet formed after the printed sheet is cut to terminate the length of the sheet to be wound or taken up onto the take-up roll. The first clamping device is configured to hold or clamp the new leading edge region of the printed sheet against movement along the transport path towards the take-up roll. The guide device is movable to redirect the printed sheet output from the printing system to a buffer zone, and the guide device is configured to redirect the printed sheet to the buffer zone when the first clamping device holds or clamps the new leading edge region of the printed sheet. Furthermore, the invention provides a corresponding method of handling take-up rolls in a printing system.