Invention Grant
- Patent Title: Compositions and methods related to graft versus host disease and treatments thereof
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Application No.: US14266535Application Date: 2014-04-30
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Publication No.: US09884096B2Publication Date: 2018-02-06
- Inventor: Shapiro Leland , Eli C. Lewis , Charles A. Dinarello
- Applicant: THE REGENTS OF THE UNIVERSITY OF COLORADO, A BODY
- Applicant Address: US CO Denver
- Assignee: THE REGENTS OF THE UNIVERSITY OF COLORADO, A BODY CORPORATE
- Current Assignee: THE REGENTS OF THE UNIVERSITY OF COLORADO, A BODY CORPORATE
- Current Assignee Address: US CO Denver
- Agency: Faegre Baker Daniels, LLP.
- Main IPC: A61K38/57
- IPC: A61K38/57 ; A61K39/00 ; A61K38/19 ; A61K38/21 ; A61K45/06 ; A61K35/39 ; C07K16/40 ; C07K16/46
Abstract:
Embodiments of the present invention illustrate methods of treating and preventing transplantation and side effects associated with transplantation. In particular, the present invention relates to compositions and methods for inhibition of graft rejection and promotion of graft survival. Thus, the invention relates to modulation of cellular activities, including graft rejection, promotion of graft survival, graft versus host rejection and conditions commonly associated with graft rejection. More particularly, the present invention relates to the inhibitory compounds comprising naturally occurring and man-made inhibitors of serine protease and inducers of other alpha1-antitrypsin activities.
Public/Granted literature
- US20140242096A1 COMPOSITIONS AND METHODS RELATED TO GRAFT VERSUS HOST DISEASE AND TREATMENTS THEREOF Public/Granted day:2014-08-28
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