Invention Grant
- Patent Title: Process for the preparation of halo-substituted trifluoroacetophenones
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Application No.: US15515303Application Date: 2015-10-07
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Publication No.: US09862937B2Publication Date: 2018-01-09
- Inventor: Denis Gribkov
- Applicant: SYNGENTA PARTICIPATIONS AG
- Applicant Address: CH Basel
- Assignee: Syngenta Participations AG
- Current Assignee: Syngenta Participations AG
- Current Assignee Address: CH Basel
- Agent R. Kody Jones
- Priority: EP14188743 20141014
- International Application: PCT/EP2015/073119 WO 20151007
- International Announcement: WO2016/058882 WO 20160421
- Main IPC: C07C45/63
- IPC: C07C45/63 ; C07C45/46 ; C07C201/12 ; C12N9/10 ; C12P19/44

Abstract:
The invention relates to a process for the preparation of a compound of formula I (I), wherein R1 is hydrogen, fluoro or chloro; which process comprises a) reacting a compound of formula II (II), wherein R1 is hydrogen, fluoro or chloro; with a nitration agent to the compound of formula (III), wherein R1 is hydrogen, fluoro or chloro; and b) reacting the compound of formula III with chlorine gas at temperature from 180° C. to 250° C. to the compound of formula I.
Public/Granted literature
- US20170218347A1 PROCESS FOR THE PREPARATION OF HALO-SUBSTITUTED TRIFLUOROACETOPHENONES Public/Granted day:2017-08-03
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