Invention Grant
- Patent Title: Monoclonal antibody which specifically recognizes B cell lymphoma and use thereof
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Application No.: US14639679Application Date: 2015-03-05
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Publication No.: US09862775B2Publication Date: 2018-01-09
- Inventor: Byoung Se Kwon , Kwang-Hui Kim , Young-Ho Kim , Ho-Sik Oh , Don-Gil Lee , Seung-Joo Lee , Beom-Kyu Choi , Insoo Park , Chungyong Han
- Applicant: Eutilex Co., Ltd.
- Applicant Address: KR Seoul
- Assignee: Eutilex Co., Ltd.
- Current Assignee: Eutilex Co., Ltd.
- Current Assignee Address: KR Seoul
- Agency: McDermott Will Emery LLP
- Priority: KR10-2014-0026252 20140305
- Main IPC: C07K16/00
- IPC: C07K16/00 ; C07K16/30 ; A61K47/48 ; G01N33/577 ; C07K16/28 ; G01N33/574 ; A61K39/00

Abstract:
Provided is a monoclonal antibody which specifically recognizes B cell lymphoma cells and a use thereof. More specifically, provided are the monoclonal antibody; a pharmaceutical composition for preventing or treating B cell lymphoma including the monoclonal antibody; a composition for diagnosing B cell lymphoma including the monoclonal antibody; a method for providing information for diagnosing B cell lymphoma using the monoclonal antibody; a chimeric antigen receptor (CAR) protein including i) the antibody, ii) a transmembrane domain, and iii) an intracellular signaling domain; a recombinant vector which expresses the CAR protein; a CAR-modified T cell transformed with the recombinant vector; a pharmaceutical composition for preventing or treating B cell lymphoma including the CAR-modified T cell; and an antibody-drug conjugate wherein the monoclonal antibody and a drug are conjugated.
Public/Granted literature
- US20170306043A9 Monoclonal Antibody Which Specifically Recognizes B Cell Lymphoma and Use Thereof Public/Granted day:2017-10-26
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