Methods and apparatus for acknowledgment of multiple user uplink are provided. In one aspect, a method of wireless communication includes receiving a first wireless message from a first station at least partially concurrently with receiving a second wireless message from a second station, generating a first acknowledgment message in response to receiving the first wireless message, generating a second acknowledgement message in response to receiving the second wireless message, and transmitting the first acknowledgment message to the first station at least partially concurrently with transmitting the second acknowledgement message to the second station.