Disclosed embodiments pertain to a method of generating a Positioning Reference Signal (PRS) sequence for a system comprising a plurality of physical transmitting antenna elements serving a single cell. In some embodiments, the method may comprise: assigning a distinct Physical Antenna Port (PAP) identifier (ID) to a subset of the plurality of physical transmitting antenna elements; and generating PRS sequences for the subset of the plurality of physical transmitting antenna elements, wherein each PRS sequence corresponds to a physical transmitting antenna element in the subset of the plurality of physical transmitting antenna elements, and each PRS sequence has a corresponding frequency shift based, at least in part, on the PAP ID (h) of the corresponding physical transmitting antenna element.