Gesture-based communication systems and methods for communicating with healthcare personnel are disclosed. According to an aspect, a system is disclosed that includes a movement detector configured to detect movement of muscle and to generate a wireless signal in response to detection of the muscle movement. The system also includes a base station in wireless communication with the movement detector, and configured to implement a predetermined action based on the wireless signal. The base station may be configured to interface with a healthcare call system such as in a hospital environment. The base station may control the healthcare call system to communicate a notification signal based on the wireless signal.