Invention Grant
![Pyrrolo[2,1-F[1,2,4]triazine compounds, preparation methods and applications thereof](/docs/US/2017-08-08/US09724352B2/abs.jpg.600x600.jpg)
- Patent Title: Pyrrolo[2,1-F[1,2,4]triazine compounds, preparation methods and applications thereof
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Application No.: US15269069Application Date: 2016-09-19
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Publication No.: US09724352B2Publication Date: 2017-08-08
- Inventor: Chunhao Yang , Linghua Meng , Yanhong Chen , Xiang Wang , Cun Tan , Jiapeng Li , Jian Ding , Yi Chen
- Applicant: Shanghai Institute of Materia Medica, Chinese Academy of Sciences , Shanghai Haihe Pharmaceutical Co., Ltd.
- Applicant Address: CN Shanghai CN Shanghai
- Assignee: Shanghai Institute of Materia Medica, Chinese Academy of Sciences,Shanghai Haihe Pharmaceutical Co., Ltd.
- Current Assignee: Shanghai Institute of Materia Medica, Chinese Academy of Sciences,Shanghai Haihe Pharmaceutical Co., Ltd.
- Current Assignee Address: CN Shanghai CN Shanghai
- Agency: Wolf, Greenfield & Sacks, P.C.
- Priority: CN201210177980 20120531
- Main IPC: A61K31/53
- IPC: A61K31/53 ; A61K31/5377 ; C07D419/04 ; A61P35/00 ; A61K31/5386 ; C07D419/14
![Pyrrolo[2,1-F[1,2,4]triazine compounds, preparation methods and applications thereof](/abs-image/US/2017/08/08/US09724352B2/abs.jpg.150x150.jpg)
Abstract:
The present invention relates to a pyrrolo[2,1-f][1,2,4]triazine compound, an isomer thereof or a pharmaceutically acceptable salt, ester or hydrate thereof, and a preparation method and application thereof. The pyrrolo[2,1-f][1,2,4]triazine compound has a structure expressed in general formula (I). The pyrrolo[2,1-f][1,2,4]triazine compound expressed in general formula (I) can inhibit a phosphatidylinositol-3 kinase (PI3K) signal pathway, thereby being used to prepare medicine for treating phosphatidylinositol-3 kinase related diseases such as cancer.
Public/Granted literature
- US20170000800A1 PYRROLO[2,1-F[1,2,4]TRIAZINE COMPOUNDS, PREPARATION METHODS AND APPLICATIONS THEREOF Public/Granted day:2017-01-05
Information query
