Disclosed is a frame for a secondary battery, which has an improved structure to prevent a cooling plate from being deformed or distorted due to shrinkage of a main frame. The frame for a secondary battery includes a cooling plate made of a thermally conductive material with a plate shape, and a main frame having a plurality of unit frames spaced apart from each other in a horizontal direction by a predetermined distance, the main frame being configured to surround a rim of the cooling plate and made of a material different from the cooling plate.