Invention Grant
- Patent Title: Broadly neutralizing human antibody that recognizes the receptor-binding pocket of influenza hemagglutinin
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Application No.: US14171322Application Date: 2014-02-03
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Publication No.: US09718873B2Publication Date: 2017-08-01
- Inventor: James Whittle , Stephen C. Harrison , Barton F. Haynes , Hua-Xin Liao , M. A. Moody , Thomas B. Kepler , Aaron G. Schmidt
- Applicant: Children's Hospital Boston , Duke University
- Applicant Address: US NC Durham US MA Boston
- Assignee: Duke University,Children's Medical Center Corporation
- Current Assignee: Duke University,Children's Medical Center Corporation
- Current Assignee Address: US NC Durham US MA Boston
- Agency: Mintz Levin Cohn Ferris Glovsky and Popeo, P.C.
- Agent Peter F. Corless; Christopher R. Cowles
- Main IPC: C07K16/10
- IPC: C07K16/10 ; A61K38/02 ; A61K31/713 ; A61K47/48 ; A61K51/10
Abstract:
The invention features a novel influenza antibody that specifically binds to influenza hemagglutinin and reduces or inhibits hemagglutinin binding to sialic acid. The invention also provides methods, compositions, and kits featuring the novel antibody and its use in preventing or treating influenza infection.
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