Invention Grant
- Patent Title: 20(S)-sulfonylamidine derivatives of camptothecin and the use thereof as a potent antitumor agent
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Application No.: US15025296Application Date: 2014-09-26
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Publication No.: US09718835B2Publication Date: 2017-08-01
- Inventor: Kuo-Hsiung Lee , Keduo Qian , Xiaoming Yang , Masuo Goto , Ying-Qian Liu , Yong-Long Zhao , Liu Yang , Mei-Juan Wang , Zhi-Jun Zhang , Tian-Shung Wu , Che-Ming Teng , Chih-Ya Wang , Shiow-Lin Pan , Sheng-Chu Kuo , Hsin-Yi Hung , Ling-Chu Chang , Yang-Chang Wu , Min-Tsang Hsieh , Chung Y. Hsu , Woei-Cherng Shyu , Chen-Huan Lin
- Applicant: China Medical University Hospital
- Applicant Address: TW Taichung US NC Chapel Hill
- Assignee: CHINA MEDICAL UNIVERSITY HOSPITAL,THE UNIVERSITY OF NORTH CAROLINA AT CHAPEL HILL
- Current Assignee: CHINA MEDICAL UNIVERSITY HOSPITAL,THE UNIVERSITY OF NORTH CAROLINA AT CHAPEL HILL
- Current Assignee Address: TW Taichung US NC Chapel Hill
- Agency: Bacon & Thomas, PLLC
- International Application: PCT/US2014/057575 WO 20140926
- International Announcement: WO2015/048365 WO 20150402
- Main IPC: C07D491/12
- IPC: C07D491/12 ; C07D471/04 ; C07D491/22 ; C07F9/6561 ; C07F7/08
Abstract:
The present invention is related to novel 20-sulfonylamidine derivatives of camptothecin (1), method of synthesizing the same, and use thereof as an antitumor agent, for examples an antitumor agent for treating nasopharyngeal, lung, breast or prostate cancer.
Public/Granted literature
- US20160229862A1 NOVEL 20(S)-SULFONYLAMIDINE DERIVATIVES OF CAMPTOTHECIN AND THE USE THEREOF AS A POTENT ANTITUMOR AGENT Public/Granted day:2016-08-11
Information query
