Provided are a driving circuit and its operation method and a display apparatus. The driving circuit comprises a boost circuit unit, a load unit and a voltage monitoring unit, the load unit is connected to a power source providing an initial input voltage, the boost circuit unit is connected to both the load unit and the voltage monitoring unit, the load unit is connected to the voltage monitoring unit; the load unit provides a resistor of fixed resistance value; and the voltage monitoring unit determines whether an actual voltage input into the boost circuit unit is smaller than a predetermined voltage, and generates a reset signal which is used to control the driving circuit to restart if it is determined that the actual voltage is smaller than the predetermined voltage. The driving circuit can perform self-detection of its own electro-static electricity, and perform self-recovery when detecting that an electro-static current exceeds the maximum current that the driving circuit can withstand, such that the capability of anti electro-static electricity of the display apparatus is improved.