Invention Grant
- Patent Title: Process for the production of hyaluronic acid in Escherichia coli or bacillus megaterium
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Application No.: US14884274Application Date: 2015-10-15
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Publication No.: US09695453B2Publication Date: 2017-07-04
- Inventor: Vincenza Corsa , Alessandro Negro , Sonia Bisicchia
- Applicant: FIDIA FARMACEUTICI S.P.A.
- Applicant Address: IT Abano Terme
- Assignee: FIDIA FARMACEUTICI S.P.A.
- Current Assignee: FIDIA FARMACEUTICI S.P.A.
- Current Assignee Address: IT Abano Terme
- Agency: Birch, Stewart, Kolasch & Birch, LLP
- Priority: ITMI2010A1641 20100909
- Main IPC: C12P19/26
- IPC: C12P19/26 ; C12P19/04 ; C08B37/08 ; C12N9/04 ; C12N9/10 ; C12N9/12 ; C12N9/92 ; C12N15/75
Abstract:
A method of producing hyaluronic acid (HA) in Escherichia coli and Bacillus megaterium through episomal plasmid vectors wherein the gene is under the control of strong promoter T7, preferably under the control of strong promoter T7 of bacteriophage T7, and a system for the selection of stable bacterial strains producing high levels of hyaluronic acid, are provided.
Public/Granted literature
- US20160032337A1 PROCESS FOR THE PRODUCTION OF HYALURONIC ACID IN ESCHERICHIA COLI OR BACILLUS MEGATERIUM Public/Granted day:2016-02-04
Information query
