- Patent Title: Vaccine prepared utilizing human parainfluenza virus type 2 vector
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Application No.: US14655417Application Date: 2013-12-25
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Publication No.: US09695444B2Publication Date: 2017-07-04
- Inventor: Masayuki Fukumura , Junpei Ohtsuka , Tetsuya Nosaka , Masato Tsurudome , Mitsuo Kawano , Ken-ichiro Hara
- Applicant: BioComo, Inc. , Mie University
- Applicant Address: JP Mie JP Mie
- Assignee: BIOCOMO INC.,MIE UNIVERSITY
- Current Assignee: BIOCOMO INC.,MIE UNIVERSITY
- Current Assignee Address: JP Mie JP Mie
- Agency: Pearne & Gordon LLP
- Priority: JP2012-283421 20121226
- International Application: PCT/JP2013/007598 WO 20131225
- International Announcement: WO2014/103310 WO 20140703
- Main IPC: C12N15/00
- IPC: C12N15/00 ; C12N15/86 ; C12N7/00 ; A61K39/00 ; A61K39/145 ; C12N15/09 ; A61K39/12 ; A61K39/155
Abstract:
Disclosed are: a virus vector in which a gene encoding an antigenic polypeptide is integrated in human parainfluenza virus type 2 gene, wherein the antigenic polypeptide is expressed in the form of a fusion protein with a viral structural protein; and a method for producing the same. The virus vector of the present invention contains a quantitatively large amount of the antigenic peptide on the virus particle and can efficiently deliver the antigenic polypeptide to a target cell.
Public/Granted literature
- US20150329874A1 VACCINE PREPARED UTILIZING HUMAN PARAINFLUENZA VIRUS TYPE 2 VECTOR Public/Granted day:2015-11-19
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