Invention Grant
- Patent Title: Process for the preparation of drospirenone
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Application No.: US14768659Application Date: 2013-02-20
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Publication No.: US09695213B2Publication Date: 2017-07-04
- Inventor: Roberto Lenna , Johannes Bernardus Maria Rewinkel , Francesco Barbieri , Maria Giovanna Luoni
- Applicant: Industriale Chimica S.r.l.
- Applicant Address: IT
- Assignee: INDUSTRIALE CHIMICA S.R.L.
- Current Assignee: INDUSTRIALE CHIMICA S.R.L.
- Current Assignee Address: IT
- Agency: Fish & Tsang, LLP
- International Application: PCT/IB2013/051377 WO 20130220
- International Announcement: WO2014/128525 WO 20140828
- Main IPC: C07D307/94
- IPC: C07D307/94 ; C07J53/00
Abstract:
A process is described wherein, by employing 17α-(3-hydroxypropyl)-6β,7β;15β,16β-dimethylene-5β-androstane-3β,5,17β-triol (II) as starting product, in a single stage reaction there is obtained drospirenone, (I), a synthetic steroid with progestogenic, antimineralocorticoid and antiandrogenic action, that is useful for preparing pharmaceutical compositions with contraceptive action.
Public/Granted literature
- US20160002284A1 Process for the Preparation of Drospirenone Public/Granted day:2016-01-07
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