- Patent Title: Substituted imidazo[1,5-a]pyrazines as CGRP receptor antagonists
-
Application No.: US14433693Application Date: 2013-10-14
-
Publication No.: US09695176B2Publication Date: 2017-07-04
- Inventor: Andrew P. Degnan
- Applicant: BRISTOL-MYERS SQUIBB COMPANY
- Applicant Address: US NJ Princeton
- Assignee: Bristol-Myers Squibb Company
- Current Assignee: Bristol-Myers Squibb Company
- Current Assignee Address: US NJ Princeton
- Agent James Epperson
- International Application: PCT/US2013/064791 WO 20131014
- International Announcement: WO2014/062548 WO 20140424
- Main IPC: A61K31/4985
- IPC: A61K31/4985 ; C07D487/04
![Substituted imidazo[1,5-a]pyrazines as CGRP receptor antagonists](/abs-image/US/2017/07/04/US09695176B2/abs.jpg.150x150.jpg)
Abstract:
The disclosure generally relates to the novel compounds of formula I, including pharmaceutically acceptable salts, which are CGRP receptor antagonists. The disclosure also relates to pharmaceutical compositions and methods for using the compounds in the treatment of CGRP related disorders including migraine and other headaches, neurogenic vasodilation, neurogenic inflammation, thermal injury, circulatory shock, flushing associated with menopause, airway inflammatory diseases such as asthma, and chronic obstructive pulmonary disease (COPD).
Public/Granted literature
- US20150274734A1 CGRP RECEPTOR ANTAGONISTS Public/Granted day:2015-10-01
Information query
IPC分类: